Nitric Oxide Insufficiency, Platelet Activation, and Arterial Thrombosis

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Furchgott, R. F., & Zawadzki, J. V. (1980) · Nature · doi:10.1038/288373a0 · Cited by 12,064

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704

Biochemistry of nitric oxide and its redox-activated forms

Stamler, J. S., Singel, D. J., & Loscalzo, J. (1992) · Science · doi:10.1126/science.1281928 · Cited by 2,744

Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

Laufs, U., Fata, V. L., Plutzky, J., & Liao, J. K. (1998) · Circulation · doi:10.1161/01.cir.97.12.1129 · Cited by 1,837

ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91481-4 · Cited by 1,437

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

Rubbo, H., Radí, R., Trujillo, M., Telleri, R., Kalyanaraman, B., Barnes, S., KIRK, M. C., & Freeman, B. Α. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47160-8 · Cited by 1,350

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

Stamler, J. S., Jaraki, O., Osborne, J., Simon, D. I., Keaney, J., Vita, J., Singel, D., Valeri, C. R., & Loscalzo, J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.16.7674 · Cited by 1,238

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

Ignarro, L. J., Byrns, R. E., Buga, G. M., & Wood, K. S. (1987) · Circulation Research · doi:10.1161/01.res.61.6.866 · Cited by 1,164

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1987.tb11310.x · Cited by 811

Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine.

Katsuki, S., Arnold, W. P., Mittal, C. K., & Murad, F. (1977) · PubMed · Cited by 700

Lipid-based carriers for controlled delivery of nitric oxide

Elnaggar, M. A., Subbiah, R., Han, D. K., & Joung, Y. K. (2017) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2017.1285904 · Cited by 37

Oxidative stress, the renin-angiotensin system, and atherosclerosis

Landmesser, U. (2003) · European Heart Journal Supplements · doi:10.1016/s1520-765x(03)90057-5 · Cited by 37

IL-37 Attenuates Platelet Activation and Thrombosis Through IL-1R8 Pathway

Chen, Y., Hong, J., Zhong, H., Zhao, Y., Li, J., Shen, W., Luo, X., Shi, H., Hu, L., Liu, J., et al. (2023) · Circulation Research · doi:10.1161/circresaha.122.321787 · Cited by 37

Platelet Oxidative Stress and its Relationship with Cardiovascular Diseases in Type 2 Diabetes Mellitus Patients

Haouari, M. E. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867324666171005114456 · Cited by 37

Characterization of the Oxidative Stress in Renal Ischemia/Reperfusion‐Induced Cardiorenal Syndrome Type 3

Caio‐Silva, W., Dias, D. D. S., Junho, C. V. C., Panico, K., Neres-Santos, R. S., Pelegrino, M. T., Pieretti, J. C., Seabra, A. B., Angelis, K. D., & Carneiro‐Ramos, M. S. (2020) · BioMed Research International · doi:10.1155/2020/1605358 · Cited by 36

eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering

McIlhenny, S. E., Zhang, P., Tulenko, T. N., Comeau, J. A., Fernandez, S., Policha, A., Ferroni, M. C., Faul, E. J., Bagameri, G., Shapiro, I. M., et al. (2013) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1645 · Cited by 36

Cardiovascular Effects of Losartan and Its Relevant Clinical Application

Xu, F., Mao, C., Hu, Y., Rui, C., Xu, Z., & Zhang, L. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709789178046 · Cited by 36

Risk of venous and arterial thromboembolic events associated with VEGFR-TKIs: a meta-analysis

Liu, B., Ding, F., Zhang, D., & Wei, G. (2017) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-017-3386-6 · Cited by 35

Nitric oxide inhibits von Willebrand factor‐mediated platelet adhesion and spreading through regulation of integrin αIIbβ3 and myosin light chain

Roberts, W., Michno, A., Aburima, A. A., & Naseem, K. M. (2009) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2009.03619.x · Cited by 35

The Potential of Flavanol and Procyanidin Intake to Influence Age-Related Vascular Disease

Holt, R. R., Heiß, C., Kelm, M., & Keen, C. L. (2012) · Journal of Nutrition in Gerontology and Geriatrics · doi:10.1080/21551197.2012.702541 · Cited by 35

Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow

Rogers, N. M., Seeger, F., Garcin, E. D., Roberts, D. D., & Isenberg, J. S. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00134 · Cited by 39

Near-Infrared II Photobiomodulation Preconditioning Ameliorates Stroke Injury via Phosphorylation of eNOS

Yokomizo, S., Kopp, T., Roeßing, M., Morita, A., Lee, S., Cho, S., Ogawa, E., Komai, E., Inoue, K., Fukushi, M., et al. (2024) · Stroke · doi:10.1161/strokeaha.123.045358 · Cited by 34

Vasomotor Regulation of Coronary Microcirculation by Oxidative Stress: Role of Arginase

Kuo, L., & Hein, T. W. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00237 · Cited by 33

Potential therapeutic action of nitrite in sickle cell disease

Wajih, N., Basu, S., Jailwala, A., Kim, H. W., Ostrowski, D., Perlegas, A. S., Bolden, C. A., Buechler, N. L., Gladwin, M. T., Caudell, D. L., et al. (2017) · Redox Biology · doi:10.1016/j.redox.2017.05.006 · Cited by 33

Comparison of Copper(II)–Ligand Complexes as Mediators for Preparing Electrochemically Modulated Nitric Oxide-Releasing Catheters

Konopińska, K. K., Schmidt, N. J., Hunt, A. P., Lehnert, N., Wu, J., Xi, C., & Meyerhoff, M. E. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b05917 · Cited by 33

Noncoding RNAs in Vascular Aging

Cao, Q., Wu, J., Wang, X., & Song, C. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/7914957 · Cited by 33

Peripheral Arterial Disease: A Review of Disease Awareness and Management

Watson, K., Watson, B. D., & Pater, K. S. (2006) · The American Journal of Geriatric Pharmacotherapy · doi:10.1016/j.amjopharm.2006.12.006 · Cited by 33

Endothelial vasodilatation in newborns is related to body size and maternal hypertension

Touwslager, R. N. H., Houben, A. J. H. M., Gielen, M., Zeegers, M. P., Stehouwer, C. D. A., Zimmermann, L. J. I., Kessels, A. G. H., Gerver, W. M., Blanco, C. E., & Mulder, A. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834d75c6 · Cited by 33

Inhibition of inducible nitric oxide synthase attenuates platelet adhesion in subpleural arterioles caused by lung ischemia-reperfusion in rabbits

Ovechkin, A. V., Lominadze, D. G., Sedoris, K. C., Gozal, E., Robinson, T., & Roberts, A. M. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01302.2004 · Cited by 33

Matrix metalloproteinase-7 in platelet-activated macrophages accounts for cardiac remodeling in uremic mice

Yang, Y., Lu, M., Wang, C., Song, M., Li, C., Chen, M., Zhou, J., & Mei, C. (2020) · Basic Research in Cardiology · doi:10.1007/s00395-020-0789-z · Cited by 32

T-786C Polymorphism of the nos-3 Gene and the Endothelial Cell Response to Fluid Shear Stress—A Proteome Analysis

Asif, A. R., Oellerich, M., Armstrong, V. W., Hecker, M., & Cattaruzza, M. (2009) · Journal of Proteome Research · doi:10.1021/pr800998k · Cited by 32

Comparative angioprotective effects of magnesium compounds

Kharitonova, M. V., Iezhitsa, I. N., Zheltova, A. A., Ozerov, A. A., Спасов, А. А., & Skalny, A. V. (2014) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2014.06.026 · Cited by 32

Endothelial Cell Aging: How miRNAs Contribute?

Yamakuchi, M., & Hashiguchi, T. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7070170 · Cited by 32

Antiplatelet Agents for the Prevention of Cardiovascular Disease in Diabetes Mellitus

Colwell, J. A. (2004) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200404020-00003 · Cited by 32

Young male smokers have altered platelets and endothelium that precedes atherosclerosis

Casey, R. G., Joyce, M., Roche‐Nagle, G., Cox, D. M., & Bouchier‐Hayes, D. J. (2004) · Journal of Surgical Research · doi:10.1016/s0022-4804(03)00343-3 · Cited by 31

The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1

Fledderus, J., Vanchin, B., Rots, M. G., & Krenning, G. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11020103 · Cited by 31

Nitric Oxide–Eluting Polyurethanes — Vascular Grafts of the Future?

Verma, S., & Marsden, P. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmcibr052030 · Cited by 31

Gasotransmitters and platelets

Truss, N. J., & Warner, T. D. (2011) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.07.001 · Cited by 31

Balancing role of nitric oxide in complement‐mediated activation of platelets frommCd59aandmCd59bdouble‐knockout mice

Qin, X., Hu, W., Song, W., Blair, P. S., Wu, G., Hu, X., Song, Y., Bauer, S. M., Feelisch, M., Leopold, J. A., et al. (2009) · American Journal of Hematology · doi:10.1002/ajh.21363 · Cited by 31

S-Nitrosocaptopril prevents cancer metastasis in vivo by creating the hostile bloodstream microenvironment against circulating tumor cells

Lu, Y., Lian, S., Ye, Y., Yu, T., Liang, H., Cheng, Y., Xie, J., Zhu, Y., Xie, X., Yu, S., et al. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.10.020 · Cited by 31

Platelet-derived NO slows thrombus growth on a collagen type III surface.

Williams, R. H., & Nollert, M. U. (2004) · Thrombosis Journal · doi:10.1186/1477-9560-2-11 · Cited by 31

AGEING, OESTROGEN, PLATELETS AND THROMBOTIC RISK

Miller, V. M., Jayachandran, M., & Owen, W. G. (2007) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2007.04685.x · Cited by 31

Regulation by Nitric Oxide of Endotoxin-Induced Tissue Factor and Plasminogen Activator Inhibitor-1 in Endothelial Cells

Ruiz, A. P., Montes, R., Velasco, F., López-Pedrera, C., Páramo, J. A., Orbe, J., Hermida, J., & Rocha, E. A. V. (2002) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1613355 · Cited by 31

Drug Insight: statins for nonischemic heart failure—evidence and potential mechanisms

Lipinski, M. J., Abbate, A., Fuster, V., & Vetrovec, G. W. (2007) · Nature Clinical Practice Cardiovascular Medicine · doi:10.1038/ncpcardio0855 · Cited by 31

Methotrexate and cardiovascular prevention: an appraisal of the current evidence

Mangoni, A. A., Sotgia, S., Zinellu, A., Carru, C., Pintus, G., Damiani, G. B., Erre, G. L., & Tommasi, S. (2023) · Therapeutic Advances in Cardiovascular Disease · doi:10.1177/17539447231215213 · Cited by 31

Eplerenone improves vascular function and reduces platelet activation in diabetic rats.

Schäfer, A., Vogt, C., Fraccarollo, D., Widder, J., Flierl, U., Hildemann, S. K., Ertl, G., & Bauersachs, J. K. (2010) · PubMed · Cited by 30

NO in Viral Infections: Role and Development of Antiviral Therapies

Sodano, F., Gazzano, E., Fruttero, R., & Lazzarato, L. (2022) · Molecules · doi:10.3390/molecules27072337 · Cited by 30

Do Statins have a Role in Reduction/Prevention of Post‐PCI Restenosis?

Prasad, K. (2011) · Cardiovascular Therapeutics · doi:10.1111/j.1755-5922.2011.00302.x · Cited by 32

Nonlipid-lowering effects of statins

Sorrentino, S. A., & Landmesser, U. (2005) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-005-0031-1 · Cited by 31

N-Ethylmaleimide-sensitive factor: a redox sensor in exocytosis

Lowenstein, C. J., & Tsuda, H. (2006) · Biological Chemistry · doi:10.1515/bc.2006.173 · Cited by 30

SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency

Carrizzo, A., Iside, C., Nebbioso, A., Carafa, V., Damato, A., Sciarretta, S., Frati, G., Nonno, F. D., Valenti, V., Ciccarelli, M., et al. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04429-5 · Cited by 29

The Impact of an Aging Population on the Diagnosis of Pulmonary Embolism: Comparison of Young and Elderly Patients

Castelli, R., Bergamaschini, L. C., Sailis, P., Pantaleo, G., & Porro, F. (2007) · Clinical and Applied Thrombosis/Hemostasis · doi:10.1177/1076029607308860 · Cited by 29

Antithrombogenic properties of a nitric oxide-releasing dextran derivative: evaluation of platelet activation and whole blood clotting kinetics

Damodaran, V. B., Leszczak, V., Wold, K. A., Lantvit, S. M., Popat, K. C., & Reynolds, M. M. (2013) · RSC Advances · doi:10.1039/c3ra45521a · Cited by 29

Intravenous release of NO from lipidic microbubbles accelerates deep vein thrombosis resolution in a rat model

Wang, C., Yang, F., Xu, Z., Shi, D., Chen, D., Dai, J., Gu, N., & Jiang, Q. (2013) · Thrombosis Research · doi:10.1016/j.thromres.2012.11.002 · Cited by 28

2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells

Ladurner, A., Atanasov, A. G., Heiß, E. H., Baumgartner, L., Schwaiger, S., Rollinger, J. M., Stuppner, H., & Dirsch, V. M. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.06.029 · Cited by 28

Paraoxonase 1 Gene Polymorphism Does Not Affect Clopidogrel Response Variability but Is Associated with Clinical Outcome after PCI

Park, K. W., Park, J. J., Kang, J., Jeon, K., Kang, S., Han, J., Lee, S. E., Yang, H., Lee, H., Kang, H., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0052779 · Cited by 28

African Adders: Partial Characterization of Snake Venoms from Three Bitis Species of Medical Importance and Their Neutralization by Experimental Equine Antivenoms

Paixão-Cavalcante, D., Kuniyoshi, A. K., Portaro, F. C. V., da Silva, W. D., & Tambourgi, D. V. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003419 · Cited by 28

Regulation of protein kinase C by nitroarachidonic acid: Impact on human platelet activation

Bonilla, L., O’Donnell, V. B., Clark, S., Rubbo, H., & Trostchansky, A. (2013) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2013.03.001 · Cited by 29

Sickle Cell Disease: New Insights into Pathophysiology and Treatment

Inati, A. C., Koussa, S., Taher, A. T., & Perrine, S. P. (2008) · Pediatric Annals · doi:10.3928/00904481-20080501-07 · Cited by 28

Mean platelet volume, platelet distribution width and platelet count in erectile dysfunction: A systematic review and meta-analysis

Ren, Z., Ren, P., Yang, B., Liao, J., Liu, S.-Z., Lu, D., Wei, X., Liu, L.-R., & Dong, Q. G. (2017) · Andrologia · doi:10.1111/and.12777 · Cited by 28

Particulate Pollution and Endothelial Function

Rajagopalan, S., Sun, Q., & Chen, L. (2005) · Circulation · doi:10.1161/circulationaha.105.540872 · Cited by 28

Modulation of cellular bioenergetics by CO-releasing molecules and NO-donors inhibits the interaction of cancer cells with human lung microvascular endothelial cells

Stojak, M., Kaczara, P., Motterlini, R., & Chłopicki, S. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.09.005 · Cited by 27

Low levels of nitric oxide promotes heme maturation into several hemeproteins and is also therapeutic

Ghosh, A., Sumi, M. P., Tupta, B., Okamoto, T., Aulak, K. S., Tsutsui, M., Shimokawa, H., ERZURUM, S. C., & Stuehr, D. J. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102478 · Cited by 27

Mononuclear cell therapy reverts cuff-induced thrombosis in apolipoprotein E-deficient mice

Freitas‐Lima, L. C., Porto, M. L., Campagnaro, B. P., Tonini, C. L., Nogueira, B. V., Pereira, T. M., Vasquez, E. C., & Meyrelles, S. S. (2012) · Lipids in Health and Disease · doi:10.1186/1476-511x-11-96 · Cited by 27

The effect of reactive oxygen species on whole blood aggregation and the endothelial cell-platelet interaction in patients with coronary heart disease

Watt, J., Ewart, M., Greig, F. H., Oldroyd, K. G., Wadsworth, R. M., & Kennedy, S. (2012) · Thrombosis Research · doi:10.1016/j.thromres.2012.03.024 · Cited by 27

Anti-inflammatory and antioxidant activity of Trachyspermum ammi seeds in collagen induced arthritis in rats.

Umar, S., Asif, M., Sajad, M., Ansari, M. M., Hussain, U., Ahmad, W., Siddiqui, S. A., Ahmad, S., & Khan, H. A. (2012) · International Journal of Drug Development and Research · Cited by 27

Soluble Guanylyl Cyclase Activation With HMR1766 Attenuates Platelet Activation in Diabetic Rats

Schäfer, A., Flierl, U., Kobsar, A. L., Eigenthaler, M., Ertl, G., & Bauersachs, J. K. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000249407.92147.12 · Cited by 27

Preventive effect of l-carnitine and its derivatives on endothelial dysfunction and platelet aggregation

Mohammadi, M. R., Talasaz, A. H., & Alidoosti, M. (2016) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2016.06.009 · Cited by 26

Fluid-structure coupled biotransport processes in aortic valve disease

Sadrabadi, M. S., Hedayat, M., Borazjani, I., & Arzani, A. (2021) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2021.110239 · Cited by 26

Regulation of the functional and mechanical properties of platelet and red blood cells by nitric oxide donors

Shamova, E. V., Бичан, О. Д., Drozd, E. S., Gorudko, I. V., Чижик, С. А., Шумаев, К. Б., Cherenkevich, S. N., & Vanin, A. F. (2011) · BIOPHYSICS · doi:10.1134/s0006350911020278 · Cited by 26

Thiol-metabolizing proteins and endothelial redox state: differential modulation of eNOS and biopterin pathways

Sugiyama, T., & Michel, T. M. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00767.2009 · Cited by 26

Genetics of thrombophilia: impact on atherogenesis

Voetsch, B., & Loscalzo, J. (2004) · Current Opinion in Lipidology · doi:10.1097/00041433-200404000-00006 · Cited by 26

Roles and current applications of S-nitrosoglutathione in anti-infective biomaterials

Hu, Q., Ye, Z., Pi, L., & Ao, J. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100419 · Cited by 28

Inhibition of Platelet Function by the Endothelium

Beaulieu, L. M., & Freedman, J. E. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-387837-3.00017-1 · Cited by 26

Functional Tetrahydrobiopterin Synthesis in Human Platelets

Franscini, N., Bächli, E., Blau, N., Fischler, M., Walter, R. B., Schaffner, A., & Schoedon, G. (2004) · Circulation · doi:10.1161/01.cir.0000134281.82972.57 · Cited by 25

Pharmacodynamic Hybrids Coupling Established Cardiovascular Mechanisms of Action with Additional Nitric Oxide Releasing Properties

Martelli, A., Breschi, M. C., & Calderone, V. (2009) · Current Pharmaceutical Design · doi:10.2174/138161209787315611 · Cited by 26

Endothelial nitric oxide synthase is up-regulated in the umbilical cord in pregnancies complicated with intrauterine growth retardation.

Hracskó, Z., Hermesz, E., Ferencz, Á., Orvos, H., Novàk, Z., Pál, A., & Varga, I. (2009) · PubMed · Cited by 25

S-nitrosocaptopril interrupts adhesion of cancer cells to vascular endothelium by suppressing cell adhesion molecules via inhibition of the NF-кB and JAK/STAT signal pathways in endothelial cells

Lian, S., Lu, Y., Cheng, Y., Yu, T., Xie, X., Liang, H., Ye, Y., & Jia, L. (2016) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2016.08.018 · Cited by 25

INHIBITORY EFFECTS OF ENDOGENOUS l ‐ARGININE ANALOGUES ON NITRIC OXIDE SYNTHESIS IN PLATELETS: ROLE IN PLATELET HYPERAGGREGABILITY IN HYPERTENSION

de Meirelles, L. R., Mendes‐Ribeiro, A. C., Santoro, M. M., Mendes, M. A. P., Silva, M. N. D., Mann, G. E., & Brunini, T. M. C. (2007) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2007.04712.x · Cited by 26

Primary hemostasis

McMichael, M. (2005) · Journal of Veterinary Emergency and Critical Care · doi:10.1111/j.1476-4431.2005.04021.x · Cited by 25

Review: Endothelial dysfunction and pre-symptomatic atherosclerosis in type 1 diabetes — pathogenesis and identification

Browne, D., Meeking, D. R., Shaw, K. M., & Cummings, M. H. (2003) · The British Journal of Diabetes · doi:10.1177/14746514030030010401 · Cited by 24

The role of red blood cell S-nitrosation in nitrite bioactivation and its modulation by leucine and glucose

Wajih, N., Liu, X., Shetty, P., Basu, S., Wu, H., Hogg, N., Patel, R. P., Furdui, C. M., & Kim‐Shapiro, D. B. (2016) · Redox Biology · doi:10.1016/j.redox.2016.04.004 · Cited by 25

Effects of Virgin Olive Oil and Phenol-Enriched Virgin Olive Oils on Lipoprotein Atherogenicity

Farràs, M., Canyelles, M., Fitó, M., & Escolá‐Gil, J. C. (2020) · Nutrients · doi:10.3390/nu12030601 · Cited by 25

Endogenous Nitric Oxide-Releasing Microgel Coating Prevents Clot Formation on Oxygenator Fibers Exposed to In Vitro Blood Flow

Winnersbach, P., Hosseinnejad, A., Breuer, T., Fechter, T., Jakob, F., Schwaneberg, U., Rossaint, R., Bleilevens, C., & Singh, S. (2022) · Membranes · doi:10.3390/membranes12010073 · Cited by 24

Endothelial NOS-Mediated Relaxations of Isolated Thoracic Aorta of the C57BL/6J Mouse

Horváth, B., Örsy, P., & Benyó, Z. (2005) · Journal of Cardiovascular Pharmacology · doi:10.1097/01.fjc.0000154377.90069.b9 · Cited by 24

Effects of Bak Foong Pill on Blood Coagulation and Platelet Aggregation.

Gou, Y., Ho, A. L. S., Rowlands, D. K., Chung, Y. W., & Chan, H. C. (2003) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.26.241 · Cited by 24

Nitric oxide-donating aspirin (NCX 4016): an overview of its pharmacological properties and clinical perspectives

Bolla, M., Momi, S., Gresele, P., & Soldato, P. D. (2005) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-005-0026-6 · Cited by 24

Pink pressure: beetroot (Beta vulgaris rubra) as a possible novel medical therapy for chronic kidney disease

Moreira, L. D. S. G., Fanton, S., Cardozo, L., Borges, N. A., Combet, E., Shiels, P. G., Stenvinkel, P., & Mafra, D. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab074 · Cited by 23

Platelet proteomics in cardiovascular diseases

Vélez, P., & García, Á. G. (2014) · Translational Proteomics · doi:10.1016/j.trprot.2014.09.002 · Cited by 23

Nitrosyl-hemoglobin formation in rodent and human venous erythrocytes reflects NO formation from the vasculature in vivo

Zotti, F. D., Lobysheva, I. I., & Balligand, J. (2018) · PLoS ONE · doi:10.1371/journal.pone.0200352 · Cited by 23

Effect of hypercholesterolemia and of oxidative stress on the nitric oxide-cGMP pathway

Francois, M., & Kojda, G. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2004.03.026 · Cited by 23

An experiment of nature: genetic l-arginine deficiency and NO insufficiency

Loscalzo, J. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13848 · Cited by 23

Nitric Oxide and Other Novel Therapies for Pulmonary Hypertension

Claudio Napoli, A., & Loscalzo, J. (2004) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/107424840400900i101 · Cited by 23

Estrogen therapy and thrombotic risk

Miller, V. M., Jayachandran, M., Heit, J. A., & Owen, W. G. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.01.001 · Cited by 23

Trigeminal Nerve Stimulation Improves Cerebral Macrocirculation and Microcirculation After Subarachnoid Hemorrhage: An Exploratory Study

Shah, K. A., White, T. G., Powell, K., Woo, H. H., Narayan, R. K., & Li, C. (2022) · Neurosurgery · doi:10.1227/neu.0000000000001854 · Cited by 22

Nitric Oxide Dysregulation in Platelets from Patients with Advanced Huntington Disease

Carrizzo, A., Pardo, A. D., Maglione, V., Damato, A., Amico, E., Formisano, L., Vecchione, C., & Squitieri, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089745 · Cited by 22

Platelet resistance to the antiaggregating effect of N-acetyl-l-cysteine in obese, insulin-resistant subjects

Anfossi, G., Russo, I., Massucco, P., Mattiello, L., & Trovati, M. (2003) · Thrombosis Research · doi:10.1016/s0049-3848(03)00284-6 · Cited by 22

Current molecular aspects in the development and treatment of diabetes

Álvarez-Almazán, S., Filisola-Villaseñor, J. G., Alemán-González-Duhart, D., Cach, F. T., & Mendieta‐Wejebe, J. E. (2020) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-019-00717-0 · Cited by 22

Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin-induced diabetes mellitus

Schäfer, A., Fraccarollo, D., Vogt, C., Flierl, U., Hemberger, M., Tas, P. W. L., Ertl, G., & Bauersachs, J. K. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.01.013 · Cited by 22

Prothrombotic determinants of coronary atherothrombosis

Ruberg, F. L., & Loscalzo, J. (2002) · Vascular Medicine · doi:10.1191/1358863x02vm448ra · Cited by 22

ADMA and arginine derivatives in relation to non-invasive vascular function in the general population

Baum, C., Johannsen, S. S., Zeller, T., Atzler, D., Ojeda, F. M., Wild, P. S., Sinning, C. R., Lackner, K. J., Gori, T., Schwedhelm, E., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.10.101 · Cited by 21

Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products

Peck, M. J., Sanders, E. B., Scherer, G., Lüdicke, F., & Weitkunat, R. (2018) · Biomarkers · doi:10.1080/1354750x.2017.1419284 · Cited by 21

Flow adhesion of whole blood to P‐selectin: a prognostic biomarker for vaso‐occlusive crisis in sickle cell disease

Hines, P. C., Callaghan, M. U., Zaidi, A. U., Gao, X., Liu, K., White, J. U., & Tarasev, M. (2021) · British Journal of Haematology · doi:10.1111/bjh.17643 · Cited by 21

Nitric oxide: A potential etiological agent for vaso-occlusive crises in sickle cell disease

Gupta, P., & Kumar, R. (2024) · Nitric Oxide · doi:10.1016/j.niox.2024.01.008 · Cited by 21

Effects of Tadalafil on Platelets and Endothelium in Patients With Erectile Dysfunction and Cardiovascular Risk Factors: A Pilot Study

Bon, E. D., Bonanni, G., Saggiorato, G., Bassi, P., & Cella, G. (2010) · Angiology · doi:10.1177/0003319710362977 · Cited by 21

Platelet Redox Balance in Diabetic Patients With Hypertension Improved by n-3 Fatty Acids

McDonald, D., O’Kane, F., McConville, M., Devine, A. B., & McVeigh, G. E. (2012) · Diabetes Care · doi:10.2337/dc12-0304 · Cited by 21

Effects of nitrite and far-red light on coagulation

Wajih, N., Alipour, E., Rigal, F. J., Zhu, J., Perlegas, A. S., Caudell, D. L., & Kim‐Shapiro, D. B. (2020) · Nitric Oxide · doi:10.1016/j.niox.2020.11.005 · Cited by 21

Should hyperhomocysteinemia be treated in patients with atherosclerotic disease?

Maron, B. A., & Loscalzo, J. (2007) · Current Atherosclerosis Reports · doi:10.1007/s11883-007-0048-x · Cited by 22

Effects of Prasterone (dehydroepiandrosterone) on markers of cardiovascular risk and bone turnover in premenopausal women with systemic lupus erythematosus: a pilot study

Marder, W., Somers, E. C., Kaplan, M. J., Anderson, M. D., Lewis, E., & McCune, W. J. (2010) · Lupus · doi:10.1177/0961203310371156 · Cited by 21

The Role of Oxidative Stress in Endothelial Dysfunction and Vascular Inflammation

Osto, E., & Cosentino, F. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-373866-0.00022-8 · Cited by 23

Vascular nitric oxide: formation and function

Loscalzo, J., & Jin (2010) · Journal of Blood Medicine · doi:10.2147/jbm.s7000 · Cited by 240

Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis.

Freedman, J. E., Loscalzo, J., Benoit, S. E., Valeri, C. R., Barnard, M. R., & Michelson, A. D. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118522 · Cited by 171

Nitric oxide signalling in the regulation of cardiovascular and platelet function

Gkaliagkousi, Ε. (2010) · Frontiers in bioscience · doi:10.2741/3828 · Cited by 124

Platelet-Derived Nitric Oxide Signaling and Regulation

Gkaliagkousi, Ε., Ritter, J. M., & Ferro, A. (2007) · Circulation Research · doi:10.1161/circresaha.107.158410 · Cited by 175

Nitric oxide insufficiency and atherothrombosis

Voetsch, B., Jin, R. C., & Loscalzo, J. (2004) · Histochemistry and Cell Biology · doi:10.1007/s00418-004-0675-z · Cited by 121