Nitric Oxide Insufficiency, Platelet Activation, and Arterial Thrombosis

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Furchgott, R. F., & Zawadzki, J. V. (1980) · Nature · doi:10.1038/288373a0 · Cited by 12,064

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704

Biochemistry of nitric oxide and its redox-activated forms

Stamler, J. S., Singel, D. J., & Loscalzo, J. (1992) · Science · doi:10.1126/science.1281928 · Cited by 2,744

Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

Laufs, U., Fata, V. L., Plutzky, J., & Liao, J. K. (1998) · Circulation · doi:10.1161/01.cir.97.12.1129 · Cited by 1,837

ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91481-4 · Cited by 1,437

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

Rubbo, H., Radí, R., Trujillo, M., Telleri, R., Kalyanaraman, B., Barnes, S., KIRK, M. C., & Freeman, B. Α. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47160-8 · Cited by 1,350

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

Stamler, J. S., Jaraki, O., Osborne, J., Simon, D. I., Keaney, J., Vita, J., Singel, D., Valeri, C. R., & Loscalzo, J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.16.7674 · Cited by 1,238

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

Ignarro, L. J., Byrns, R. E., Buga, G. M., & Wood, K. S. (1987) · Circulation Research · doi:10.1161/01.res.61.6.866 · Cited by 1,164

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1987.tb11310.x · Cited by 811

Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine.

Katsuki, S., Arnold, W. P., Mittal, C. K., & Murad, F. (1977) · PubMed · Cited by 700

Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase

Ni, R., Peleg, T., & Gross, P. L. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.300090 · Cited by 20

The ratio of eicosapentaenoic acid to arachidonic acid is a critical risk factor for acute coronary syndrome in middle-aged older patients as well as younger adult patients

Serikawa, T., Miura, S., Okabe, M., Hongo, H., Tokutome, M., Yoshikawa, T., Takesue, K., Adachi, S., Osaka, K., Matsukawa, R., et al. (2013) · Journal of Cardiology · doi:10.1016/j.jjcc.2013.06.016 · Cited by 20

Microvascular Vasodilator Plasticity After Acute Exercise

Robinson, A. T., Fancher, I. S., Mahmoud, A. M., & Phillips, S. A. (2017) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000130 · Cited by 20

The potential of Angeli's salt to decrease nitric oxide scavenging by plasma hemoglobin

He, X., Azarov, I., Jeffers, A. B., Presley, T. D., Richardson, J., King, S. B., Gladwin, M. T., & Kim‐Shapiro, D. B. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.038 · Cited by 20

Impaired Flow-Mediated Vasodilation in vivo and Reduced Shear-Induced Platelet Reactivity in vitro in Response to Nitric Oxide in Prothrombotic, Stroke-Prone Spontaneously Hypertensive Rats

Taka, T., Ohta, Y., Seki, J., Giddings, J. C., & Yamamoto, J. (2002) · Pathophysiology of Haemostasis and Thrombosis · doi:10.1159/000070425 · Cited by 20

Influences of Increased Oxidative Stress on Endothelial Function, Platelets Function, and Fibrinolysis in Hypertension Associated with Glucose Intolerance

Tomiyama, H., Kushiro, T., Okazaki, R., Yoshida, H., Doba, N., & Yamashina, A. (2003) · Hypertension Research · doi:10.1291/hypres.26.295 · Cited by 20

Prostacyclin prevents nitric oxide‐induced megakaryocyte apoptosis

Pozner, R. G., Negrotto, S., D’Atri, L. P., Kotler, M. L., Lazzari, M. A., Gomez, R. M., & Schattner, M. A. (2005) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706200 · Cited by 20

High glucose rapidly activates the nitric oxide/cyclic nucleotide pathway in human platelets via an osmotic mechanism

Massucco, P., Mattiello, L., Russo, I., Traversa, M., Doronzo, G., Anfossi, G., & Trovati, M. (2005) · Thrombosis and Haemostasis · doi:10.1160/th04-06-0375 · Cited by 20

Phosphodiesterases as Targets for Intermittent Claudication

Liu, Y., Shakur, Y., & Kambayashi, J. (2011) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-17969-3_9 · Cited by 19

Pretreatment with β-Boswellic Acid Improves Blood Stasis Induced Endothelial Dysfunction: Role of eNOS Activation

Wang, M., Chen, M., Ding, Y., Zhu, Z., Zhang, Y., Wei, P., Wang, J., Qiao, Y., Li, L., Li, Y., et al. (2015) · Scientific Reports · doi:10.1038/srep15357 · Cited by 19

Normalization of Multiple Hemostatic Abnormalities in Uremic Type 1 Diabetic Patients After Kidney-Pancreas Transplantation

Fiorina, P., Folli, F. B., D’Angelo, A., Finzi, G., Pellegatta, F., Guzzi, V., Fedeli, C., Valle, P. D., Usellini, L., Placidi, C., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.9.2291 · Cited by 19

Effect of aspirin treatment on abacavir-associated platelet hyperreactivity in HIV-infected patients

Falcinelli, E., Francisci, D., Schiaroli, E., Minuz, P., Orsini, S. I., Malincarne, L., Sebastiano, M., Mezzasoma, A. M., Pasticci, M. B., Guglielmini, G., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.04.052 · Cited by 19

Endothelial function in normal and pathological conditions

Pizov, A. V., Pizov, N. A., Skachkova, O. A., & Пизова, Н. В. (2019) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2019-6-154-159 · Cited by 19

Advanced-glycation end-products axis: A contributor to the risk of severe illness from COVID-19 in diabetes patients

Armando Rojas, R., Lindner, C., González, I., & Morales, M. A. (2021) · World Journal of Diabetes · doi:10.4239/wjd.v12.i5.590 · Cited by 19

Review: Nutriceuticals as Antithrombotic Agents

Chakrabarti, S., & Freedman, J. E. (2010) · Cardiovascular Therapeutics · doi:10.1111/j.1755-5922.2010.00161.x · Cited by 19

The Effects of Long-term Smoking on Endothelial Nitric Oxide Synthase mRNA Expression in Human Platelets as Detected With Real-time Quantitative RT-PCR

Shimasaki, Y., Saito, Y., Yoshimura, M., Kamitani, S., Miyamoto, Y., Masuda, I., Nakayama, M., Mizuno, Y., Ogawa, H., Yasue, H., et al. (2007) · Clinical and Applied Thrombosis/Hemostasis · doi:10.1177/1076029606296402 · Cited by 19

Platelet activation patterns are different in mouse models of diabetes and chronic inhibition of nitric oxide synthesis

Różalski, M., Kassassir, H., Siewiera, K., Klepacka, A., Sychowski, R., & Watała, C. W. (2014) · Thrombosis Research · doi:10.1016/j.thromres.2014.03.041 · Cited by 18

Selenium, Stroke, and Infection: A Threefold Relationship; Where Do We Stand and Where Do We Go?

Liampas, A., Zis, P., Hadjigeorgiou, G. M., & Vavougios, G. D. (2023) · Nutrients · doi:10.3390/nu15061405 · Cited by 18

Cardiac catheterization: consequences for the endothelium and potential for nanomedicine

Sobolewski, P., & Fray, M. E. (2014) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1316 · Cited by 19

Glucose in platelet additive solutions: To add or not to add?

Gyöngyössy‐Issa, M. I. C. (2011) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2011.03.003 · Cited by 18

Mechanisms involved in platelet hyperactivation and platelet-endothelium interrelationships in diabetes mellitus

Trovati, M., & Anfossi, G. (2002) · Current Diabetes Reports · doi:10.1007/s11892-002-0020-7 · Cited by 18

Clinical haemorheology and microcirculation.

Mannini, L., Cecchi, E., Fatini, C., Marcucci, R., Liotta, A. A., Matucci‐Cerinic, M., Abbate, R., & Gensini, G. F. (2007) · PubMed · Cited by 18

The implications of biologic therapy for elective foot and ankle surgery in patients with rheumatoid arthritis

Diaper, R., Wong, E., & Metcalfe, S. A. (2017) · The Foot · doi:10.1016/j.foot.2017.01.009 · Cited by 18

Telmisartan improves vascular function and reduces platelet activation in rats with streptozotocin-induced diabetes mellitus

Schäfer, A., Flierl, U., Vogt, C., Menninger, S., Tas, P. W. L., Ertl, G., & Bauersachs, J. K. (2007) · Pharmacological Research · doi:10.1016/j.phrs.2007.05.009 · Cited by 18

Nitric Oxide Signaling and Atherothrombosis Redux

Loscalzo, J. (2018) · Circulation · doi:10.1161/circulationaha.117.032901 · Cited by 18

Identification of the Antithrombotic Mechanism of Leonurine in Adrenalin Hydrochloride-Induced Thrombosis in Zebrafish via Regulating Oxidative Stress and Coagulation Cascade

Liao, L., Zhou, M., Wang, J., Xue, X., Deng, Y., Zhao, X., Peng, C. Y., & Li, Y. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.742954 · Cited by 17

Impact of ultraviolet radiation on cardiovascular and metabolic disorders: The role of nitric oxide and vitamin D

Quan, Q., Yoon, K.-N., Lee, J. S., Kim, E. J., & Lee, D. H. (2023) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12914 · Cited by 17

Evaluating the impact of type 2 diabetes mellitus on pulmonary vascular function and the development of pulmonary fibrosis

Mzimela, N., Dimba, N. R., Sosibo, A. M., & Khathi, A. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1431405 · Cited by 17

Prevalence of Unresponsiveness to Aspirin and/or Clopidogrel in Patients With Stable Coronary Heart Disease

Lordkipanidzé, M., Diodati, J. G., Schampaert, É., Palisaitis, D., & Pharand, C. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.06.025 · Cited by 17

Hemodynamic and Hematologic Effects of Histotripsy of Free-Flowing Blood: Implications for Ultrasound-Mediated Thrombolysis

Devanagondi, R., Zhang, X., Xu, Z., Ives, K. A., Levin, A. M., Gurm, H. S., & Owens, G. E. (2015) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2015.03.022 · Cited by 19

Influence of Different β-Blockers on Platelet Aggregation in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy

Ignjatović, V., Pavlović, S. U., Miloradović, V., Andjelkovic, N. V., Davidović, G., Djurdjevic, P. M., Stolic, R. V., Irić-Ćupić, V., Simić, I., Ignjatović, V., et al. (2015) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248415581175 · Cited by 17

Fractalkine promotes platelet activation and vascular dysfunction in congestive heart failure

Hildemann, S. K., Schulz, C., Fraccarollo, D., Schöpp, C., Flierl, U., Wissel, K., Pelisek, J., Maßberg, S., Bauersachs, J. K., & Schäfer, A. (2013) · Thrombosis and Haemostasis · doi:10.1160/th13-08-0640 · Cited by 17

Hemorheologic profile in systemic sclerosis: Role of NOS3 −786T>C and 894G>T polymorphisms in modulating both the hemorheologic parameters and the susceptibility to the disease

Fatini, C., Mannini, L., Sticchi, E., Rogai, V., Guiducci, S., Conforti, M. L., Cinelli, M., Pignone, A. M., Bolli, P., Abbate, R., et al. (2006) · Arthritis & Rheumatism · doi:10.1002/art.21933 · Cited by 17

Endogenous Nitric Oxide Protects against T Cell-Dependent Lethality during Graft-versus-Host Disease and Idiopathic Pneumonia Syndrome

Hongo, D., Bryson, J. S., Kaplan, A. M., & Cohen, D. A. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.3.1744 · Cited by 17

Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin

Solomon, S. B., Bellavia, L., Sweeney, D. J., Piknova, B., Perlegas, A. S., Helms, C. C., Ferreyra, G. A., King, S. B., Raat, N. J. H., Kern, S. J., et al. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.10.548 · Cited by 16

Inflammation and thrombosis new insights

Myers, D. D. (2012) · Frontiers in Bioscience-Scholar · doi:10.2741/s289 · Cited by 16

Proteomic Signature of Thrombin-Activated Platelets After In Vivo Nitric Oxide–Donor Treatment

Peña, E., Padró, T., Molins, B., Vilahur, G., & Badimón, L. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.231852 · Cited by 16

Exogenous in vivo NO-donor treatment preserves p53 levels and protects vascular cells from apoptosis

Durán, X., Vilahur, G., & Badimón, L. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.11.016 · Cited by 16

TP508 (Chrysalin ® ) Reverses Endothelial Dysfunction and Increases Perfusion and Myocardial Function in Hearts With Chronic Ischemia

Fossum, T. W., Olszewska-Pazdrak, B., Mertens, M. M., Makarski, L. A., Miller, M. W., Hein, T. W., Kuo, L., Clubb, F. J., Fuller, G. M., & Carney, D. H. (2008) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248408321468 · Cited by 16

Endothelial Cell Activity in Chronic Obstructive Pulmonary Disease Without Severe Pulmonary Hypertension

Cella, G., Saetta, M. P., Baraldo, S., Turato, G., Papi, A. A., Casoni, G. L., & Rigno, M. (2005) · Clinical and Applied Thrombosis/Hemostasis · doi:10.1177/107602960501100410 · Cited by 16

Bioactive Peptides from Meat Proteins as Functional Food Components

Wu, J., Jahandideh, F., Yu, W., & Majumder, K. (2015) · Wiley eBooks · doi:10.1002/9781119108580.ch9 · Cited by 16

Enhancing anticoagulation and endothelial cell proliferation of titanium surface by sequential immobilization of poly(ethylene glycol) and collagen

Pan, C., Hou, Y., Ding, H., & Dong, Y. (2013) · Applied Surface Science · doi:10.1016/j.apsusc.2013.09.176 · Cited by 15

Adenylic Dinucleotides Produced by CD38 Are Negative Endogenous Modulators of Platelet Aggregation

Magnone, M., Basile, G., Bruzzese, D., Guida, L., Signorello, M. G., Chothi, M. P., Bruzzone, S., Millo, E., Qi, A., Nicholas, R. A., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m710568200 · Cited by 15

Pro-healing drug-eluting stents: a role for antioxidants?

Watt, J., Wadsworth, R. M., Kennedy, S., & Oldroyd, K. G. (2008) · Clinical Science · doi:10.1042/cs20070207 · Cited by 15

New insights into the molecular basis of the antiphospholipid syndrome

Mineo, C., & Shaul, P. W. (2011) · Drug Discovery Today Disease Mechanisms · doi:10.1016/j.ddmec.2011.12.002 · Cited by 15

Influence of intermittent hypoxia interval training on exercise-dependent erythrocyte NOS activation and blood pressure in diabetic patients

Ladage, D., Braunroth, C., Lenzen, E., Berghöfer, S., Gräf, C., Bloch, W., & Brixius, K. (2012) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y2012-138 · Cited by 15

Cholesterol-reducing agents for aneurysmal subarachnoid haemorrhage

Liu, Z., Liu, L., Zhang, Z., Chen, Z., & Zhao, B. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008184.pub2 · Cited by 14

Coombs-negative hemolytic anemia and elevated plasma hemoglobin levels in COVID-19

Lancman, G., Marcellino, B. K., Thibaud, S., & Troy, K. M. (2020) · Annals of Hematology · doi:10.1007/s00277-020-04202-3 · Cited by 14

The renaissance of nitric oxide: from improvement of stability to enhancement of endocytosis

Jia, F., Deng, Y., & Ji, J. (2018) · Materials Chemistry Frontiers · doi:10.1039/c8qm00013a · Cited by 14

A Brief History of Ideas About Platelets in Health and Disease

Coller, B. S. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-387837-3.00069-9 · Cited by 14

NO detection in biological samples: Differentiation of 14NO and 15NO using infrared laser spectroscopy

Fritsch, T., Brouzos, P., Heinrich, K., Kelm, M., Rassaf, T., Hering, P., Kleinbongard, P., & Mürtz, M. (2008) · Nitric Oxide · doi:10.1016/j.niox.2008.03.002 · Cited by 14

Ornithine transcarbamylase deficiency: A possible risk factor for thrombosis

Venkateswaran, L., Scaglia, F., McLin, V. A., Hertel, P. M., Shchelochkov, O. A., Karpen, S. J., Mahoney, D. H., & Yee, D. L. (2009) · Pediatric Blood & Cancer · doi:10.1002/pbc.22016 · Cited by 14

Loss of protease activity of ADAM15 abolishes protective effects on plaque progression in atherosclerosis

Bültmann, A., Li, Z., Wagner, S., Gawaz, M., Ungerer, M., Langer, H. F., May, A. E., & Münch, G. (2011) · International Journal of Cardiology · doi:10.1016/j.ijcard.2011.08.013 · Cited by 14

Inhibition of Platelet Function by the Endothelium

Rex, S., & Freedman, J. E. (2007) · Elsevier eBooks · doi:10.1016/b978-012369367-9/50775-8 · Cited by 14

Evidence mounts that red cells and deoxyhemoglobin can reduce nitrite to bioactive NO to mediate intravascular endocrine NO signaling: commentary on “Anti-platelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex”

Corti, P., Tejero, J., & Gladwin, M. T. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.09.020 · Cited by 13

Platelet-Inspired Nanotherapeutics for Biomedical Applications

Yang, F., Kong, Z., Ji, Q., Li, S., Sun, J., He, Z., Zhang, S., & Luo, C. (2023) · ACS Materials Letters · doi:10.1021/acsmaterialslett.2c00832 · Cited by 13

The role of fibrinolysis in the development of prediabetes-associated coronary heart disease: a focus on the plasminogen activator inhibitor -1 and its potential use as a predictive marker in diet-induced prediabetes

Gumede, N. P., & Khathi, A. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1256427 · Cited by 13

Endothelial dysfunction in young healthy men is associated with aspirin resistance

Doroszko, A., Szahidewicz-Krupska, E., Januś, A., Jakubowski, M., Turek, A., Ilnicka, P., Szuba, A., Mazur, G. J., & Derkacz, A. (2015) · Vascular Pharmacology · doi:10.1016/j.vph.2015.02.001 · Cited by 13

Plaqueta: fisiología de la activación y la inhibición

López-Farré, A. J., & Macaya, C. (2013) · Revista Española de Cardiología Suplementos · doi:10.1016/s1131-3587(13)70073-6 · Cited by 13

Towards Biohybrid Lung: Induced Pluripotent Stem Cell Derived Endothelial Cells as Clinically Relevant Cell Source for Biologization

Pflaum, M., Dahlmann, J., Engels, L., Naghilouy-Hidaji, H., Adam, D., Zöllner, J., Otto, A., Schmeckebier, S., Martin, U., Haverich, A., et al. (2021) · Micromachines · doi:10.3390/mi12080981 · Cited by 13

Are Microparticles the Missing Link between Thrombosis and Autoimmune Diseases? Involvement in Selected Rheumatologic Diseases

Cunningham, M. A., Marks, N., Barnado, A., Wirth, J. R., Gilkeson, G. S., & Markiewicz, M. (2014) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0034-1387924 · Cited by 13

The Quest for Nonthrombotic Surface Modifications to Achieve Hemocompatibility of Implantable Devices

Tchouta, L., & Bonde, P. (2015) · ASAIO Journal · doi:10.1097/mat.0000000000000283 · Cited by 14

Ascorbate attenuates red light mediated vasodilation: Potential role of S-nitrosothiols

Keszler, Á., Lindemer, B. J., Hogg, N., & Lohr, N. L. (2018) · Redox Biology · doi:10.1016/j.redox.2018.09.008 · Cited by 13

Erythrocytic bioactivation of nitrite and its potentiation by far-red light

Wajih, N., Basu, S., Ucer, K. B., Rigal, F. J., Shakya, A., Rahbar, E., Vachharajani, V., Guthold, M., Gladwin, M. T., Smith, L. M., et al. (2018) · Redox Biology · doi:10.1016/j.redox.2018.11.001 · Cited by 13

Accelerated RBC senescence as a novel pathologic mechanism of blood stasis syndrome in traditional East Asian medicine.

You, S., Park, B., & Lee, M. S. (2015) · PubMed Central · Cited by 14

Screening of the GPX3 Gene Identifies the “T” Allele of the SNP −861A/T as a Risk for Ischemic Stroke in Young Asian Indians

Akhter, M. S., Biswas, A., Rashid, H., Devi, L., Behari, M., & Saxena, R. (2014) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2014.03.010 · Cited by 13

Nitridergic Platelet Pathway Activation by Hementerin, a Metalloprotease from the Leech Haementeria depressa

Chudzinski-Tavassi, A. M., Bermejo, E., Rosenstein, R. E., Faria, F., Sarmiento, M. I. K., Alberto, F. A. R., Sampaio, M. U., & Lazzari, M. A. (2003) · Biological Chemistry · doi:10.1515/bc.2003.150 · Cited by 13

Modulation of l-arginine transport and nitric oxide production by gabexate mesylate

Leoncini, G., Pascale, R., & Signorello, M. G. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01108-5 · Cited by 13

Clinical Benefits of a Metabolic Approach in the Cardiac Rehabilitation of Patients with Coronary Artery Disease

Belardinelli, R., Lacalaprice, F., Faccenda, E., & Volpe, L. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.07.006 · Cited by 13

Downregulation of Antioxidants and Phase 2 Proteins

Zhu, H., Wang, J., Santo, A., & Li, Y. (2013) · Wiley eBooks · doi:10.1002/9781118355886.ch5 · Cited by 13

Photocontrolled release of nitric oxide for precise management of NO concentration in a solution

Zhermolenko, E. O., Karogodina, T. Y., Vorob’ev, A. Y., Панфилов, М. А., & Moskalensky, A. E. (2023) · Materials Today Chemistry · doi:10.1016/j.mtchem.2023.101445 · Cited by 12

Disinhibition of SOD-2 Expression to Compensate for a Genetically Determined NO Deficit in Endothelial Cells–Brief Report

Asif, A. R., Hecker, M., & Cattaruzza, M. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.190678 · Cited by 12

Reduction of Death Rate Due to Acute Myocardial Infarction in Subjects with Cancers through Systemic Restoration of Impaired Nitric Oxide

Ghosh, R., Ray, U., Jana, P., Bhattacharya, R., Banerjee, D., & Sinha, A. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088639 · Cited by 12

Atherosclerosis and vascular calcification in uraemia - a new experimental model.

Ivanovski, O., Nikolov, I. G., Drueke, B. T., & Massy, A. Z. (2007) · PubMed · Cited by 12

Plasma glutathione peroxidase in pediatric stroke families

Nowak‐Göttl, U., Fiedler, B., Huge, A., Niederstadt, T., Thedieck, S., Seehafer, T., & Stoll, M. (2010) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2010.04103.x · Cited by 12

Asymmetric Dimethylarginine (ADMA) Levels Display a Morning Peak in Patients with Acute Myocardial Infarction

Bergheanu, S. C., van der Laarse, A., van der Bom, J. G., van der Hoeven, B. L., le Cessie, S., de Jong, M. G., Liem, S., Schalij, M. J., & Jukema, J. W. (2011) · Disease Markers · doi:10.1155/2011/941895 · Cited by 13

Inflammation

Bergmeier, W., & Wagner, D. D. (2007) · Elsevier eBooks · doi:10.1016/b978-012369367-9/50801-6 · Cited by 12

Neuropathology and pathophysiology of stroke

Hossmann, K. A., & Heiss, W. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511691768.002 · Cited by 12

Relationship between endothelial dysfunction, oxidant stress and aspirin resistance in patients with stable coronary heart disease

Cheng, G., Shan, J., Xu, G. M., Liu, P., Zhou, Y., Zhu, Y., & Lu, X. (2007) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/j.1365-2710.2007.00823.x · Cited by 12

El consumo de nitrato y su potencial efecto benéfico sobre la salud cardiovascular

Brayan Moreno, C., Karen Soto, O., & González, D. R. (2015) · Revista chilena de nutrición · doi:10.4067/s0717-75182015000200013 · Cited by 13

GPx3 deficiency exacerbates maladaptive right ventricular remodeling in experimental pulmonary artery banding

Covington, T. A., Pilz, P. M., Mulhern, R. M., Ngoy, S., Loscalzo, A., Liu, J., Fisch, S., & Grune, J. (2023) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00379.2022 · Cited by 11

Endothelium-Mimetic Surface Modification Improves Antithrombogenicity and Enhances Patency of Vascular Grafts in Rats and Pigs

Wei, Y., Jiang, H., Chai, C., Liu, P., Qian, M., Sun, N., Gao, M., Zu, H., Yu, Y., Ji, G., et al. (2023) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.12.009 · Cited by 11

Towards use of MRI-guided ultrasound for treating cerebral vasospasm

Bonow, R. H., Silber, J. R., Enzmann, D. R., Beauchamp, N. J., Ellenbogen, R. G., & Mourad, P. D. (2016) · Journal of Therapeutic Ultrasound · doi:10.1186/s40349-016-0050-2 · Cited by 11

Is there a link between mean platelet volume and thrombotic events in antiphospholipid syndrome?

Korkmaz, S., Uslu, A. U., Şahin, Ş., Şenel, S., & Şencan, M. (2013) · Platelets · doi:10.3109/09537104.2013.824563 · Cited by 11

Inhibition by Ethanol of Shear Stress-Induced Formation of Platelet Thrombi in Whole Blood

Ekawa, K., Marumo, M., & Wakabayashi, I. (2018) · Alcohol and Alcoholism · doi:10.1093/alcalc/agy081 · Cited by 11

A new mechanism of action of thienopyridine antiplatelet drugs – A role for gastric nitrosthiol metabolism?

Anderson, R. A., Bundhoo, S. S., & James, P. E. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.08.045 · Cited by 11

Chronic cerebrovascular diseases and neuroprotection: the clinical efficacy of meldonium (Mildronat)

Tanashyan, M. M., Maksimova, M. Y., Шабалина, А. А., Федин, П. А., Medvedev, R. B., & Болотова, Т. А. (2020) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202012010114 · Cited by 11

Reactivity and Structure of Complexes of Small Molecules: Nitric Oxide

Harland, J. B., Manickas, E. C., Hunt, A. P., & Lehnert, N. (2021) · Elsevier eBooks · doi:10.1016/b978-0-08-102688-5.00111-2 · Cited by 11

NCX4016: a novel antithrombotic agent

Gresele, P., Momi, S., & Mezzasoma, A. M. (2003) · Digestive and Liver Disease · doi:10.1016/s1590-8658(03)00048-3 · Cited by 11

Diagnostic Ultrasound High Mechanical Index Impulses Restore Microvascular Flow in Peripheral Arterial Thromboembolism

Porter, T. R., Radio, S. J., Lof, J., Everbach, E. C., Powers, J., Vignon, F., Shi, W. T., & Xie, F. (2016) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2016.02.001 · Cited by 10

The effects of nitric oxide on coagulation and inflammation in ex vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass

Malfertheiner, M. V., Garrett, A., Passmore, M. R., Haymet, A. B., Webb, R. I., von Bahr, V., Millar, J. E., Schneider, B., Obonyo, N. G., Black, D. M., et al. (2023) · Artificial Organs · doi:10.1111/aor.14608 · Cited by 10

A novel ultrasound-triggered cardiac patch for targeted nitric oxide delivery to promote angiogenesis and reduce inflammation for the treatment of myocardial infarction

Xu, L., Jin, Q., Chen, Y., Cui, N., Bai, Y., Wang, Y., Li, W., Wang, W., Wang, L., Yang, Y., et al. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.164172 · Cited by 10

Phenotypic switching prevention and proliferation/migration inhibition of vascular smooth muscle cells by the ruthenium nitrosyl complex trans -[Ru(NO)Cl(cyclam](PF6)2

de Oliveira, M. G., Doro, F. G., Tfouni, E., & Krieger, M. H. (2017) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12755 · Cited by 10

Beetroot juice intake with different amounts of nitrate does not change aerobic exercise-mediated responses in heart rate variability in hypertensive postmenopausal women: A randomized, crossover and double-blind study

Carrijo, V. H. V., Amaral, A. L., Mariano, I. M., de Souza, T. C. F., Batista, J. P., de Oliveira, E. P., & Puga, G. M. (2020) · Journal of Exercise Science & Fitness · doi:10.1016/j.jesf.2020.12.001 · Cited by 12

High-intensity statin treatment is associated with reduced plaque structural stress and remodelling of artery geometry and plaque architecture

Gu, S. Z., Costopoulos, C., Huang, Y., Bourantas, C. V., Woolf, A. K., Sun, C. J., Teng, Z., Losdat, S., Räber, L., Samady, H., et al. (2021) · European Heart Journal Open · doi:10.1093/ehjopen/oeab039 · Cited by 10

Detecting Thrombophilia, Hypofibrinolysis and Reduced Nitric Oxide Production in Osteonecrosis

Glueck, C. J., Freiberg, R. A., & Wang, P. (2007) · Seminars in Arthroplasty JSES · doi:10.1053/j.sart.2007.06.005 · Cited by 10

Sterile Inflammatory Role of High Mobility Group Box 1 Protein: Biological Functions and Involvement in Disease

Gonelevue, S., Bandyopadhyay, A., Bhagat, S., Alam, I., & Khan, G. A. (2018) · Journal of Vascular Research · doi:10.1159/000491390 · Cited by 10

Oxidants and Endothelial Dysfunction

Lund, A. K. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.00712-0 · Cited by 12

Normalization of nitric oxide flux improves physiological parameters of porcine kidneys maintained on pulsatile perfusion

Gage, F. A., & Yoram Vodovotz, B. (2003) · Nitric Oxide · doi:10.1016/j.niox.2003.10.001 · Cited by 10

The biological role and future therapeutic uses of nitric oxide in extracorporeal membrane oxygenation, a narrative review

Brinkley, L. M., Brock, M. A., Stinson, G. P., Bilgili, A., Jacobs, J. P., Bleiweis, M. S., & Peek, G. J. (2024) · Perfusion · doi:10.1177/02676591241228169 · Cited by 9

Vascular nitric oxide: formation and function

Loscalzo, J., & Jin (2010) · Journal of Blood Medicine · doi:10.2147/jbm.s7000 · Cited by 240

Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis.

Freedman, J. E., Loscalzo, J., Benoit, S. E., Valeri, C. R., Barnard, M. R., & Michelson, A. D. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118522 · Cited by 171

Nitric oxide signalling in the regulation of cardiovascular and platelet function

Gkaliagkousi, Ε. (2010) · Frontiers in bioscience · doi:10.2741/3828 · Cited by 124

Platelet-Derived Nitric Oxide Signaling and Regulation

Gkaliagkousi, Ε., Ritter, J. M., & Ferro, A. (2007) · Circulation Research · doi:10.1161/circresaha.107.158410 · Cited by 175

Nitric oxide insufficiency and atherothrombosis

Voetsch, B., Jin, R. C., & Loscalzo, J. (2004) · Histochemistry and Cell Biology · doi:10.1007/s00418-004-0675-z · Cited by 121