Obesity-induced inflammatory changes in adipose tissue

Obesity is associated with macrophage accumulation in adipose tissue

Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837

A central role for JNK in obesity and insulin resistance

Hirosumi, J., Tuncman, G., Chang, L., Görgün, C. Z., Uysal, K. T., Maeda, K., Karin, M., & Hotamisligil, G. S. (2002) · Nature · doi:10.1038/nature01137 · Cited by 3,359

Differential Significance of Plasma Visfatin Concentrations according to Adiposity in Children and Adolescents

Kim, H. J., Park, S. Y., Choi, Y. J., Han, S. J., Lee, K. W., & Kim, D. J. (2013) · Hormone Research in Paediatrics · doi:10.1159/000348848 · Cited by 3,061

Protection from obesity-induced insulin resistance in mice lacking TNF-α function

Uysal, K. T., Wiesbrock, S. M., Marino, M. W., & Hotamisligil, G. S. (1997) · Nature · doi:10.1038/39335 · Cited by 2,234

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

Maeda, N., Shimomura, I., Kishida, K., Nishizawa, H., Matsuda, M., Nagaretani, H., Furuyama, N., Kondo, H., Takahashi, M., Arita, Y., et al. (2002) · Nature Medicine · doi:10.1038/nm724 · Cited by 2,114

Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ

Yuan, M., Konstantopoulos, N., Lee, J., Hansen, L., Li, Z.-W., Karin, M., & Shoelson, S. E. (2001) · Science · doi:10.1126/science.1061620 · Cited by 1,884

PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

Tontonoz, P., Nagy, L., Alvarez, J. G. A., Thomázy, V. A., & Evans, R. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81575-5 · Cited by 1,815

Effect of vitamin D supplementation along with weight loss diet on meta‐inflammation and fat mass in obese subjects with vitamin D deficiency: A double‐blind placebo‐controlled randomized clinical trial

Lotfi‐Dizaji, L., Mahboob, S., Aliashrafi, S., Vaghef‐Mehrabany, E., Ebrahimi‐Mameghani, M., & Morovati, A. (2018) · Clinical Endocrinology · doi:10.1111/cen.13861 · Cited by 55

Waist circumference is positively correlated with markers of inflammation and negatively with adiponectin in women with metabolic syndrome

Ackermann, D., Jones, J. L., Barona, J., Calle, M. C., Kim, J. E., LaPia, B. J., Volek, J. S., McIntosh, M. S., Kalynych, C. J., Najm, W. I., et al. (2011) · Nutrition Research · doi:10.1016/j.nutres.2011.02.004 · Cited by 51

Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue

Walley, A. J., Jacobson, P., Falchi, M., Bottolo, L., Andersson‐Assarsson, J. C., Petretto, E. G., Bonnefond, A., Vaillant, E., Lecœur, C., Vatin, V., et al. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.22 · Cited by 53

Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm

Kugo, H., Zaima, N., Tanaka, H., Mouri, Y., Yanagimoto, K., Hayamizu, K., Hashimoto, K., Sasaki, T., Sano, M., Yata, T., et al. (2016) · Scientific Reports · doi:10.1038/srep31268 · Cited by 51

Anthocyanins from colored maize ameliorated the inflammatory paracrine interplay between macrophages and adipocytes through regulation of NF-κB and JNK-dependent MAPK pathways

Zhang, Q., Luna‐Vital, D. A., & de Mejı́a, E. G. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.01.016 · Cited by 51

The Cardiovascular Continuum in Asia-A New Paradigm for the Metabolic Syndrome

Cheung, B. M. Y. (2005) · Journal of Cardiovascular Pharmacology · doi:10.1097/01.fjc.0000171752.43564.35 · Cited by 50

Adiposopathy is a more rational treatment target for metabolic disease than obesity alone

Bays, H. E., & Dujovne, C. A. (2006) · Current Atherosclerosis Reports · doi:10.1007/s11883-006-0052-6 · Cited by 51

SERPINA3C ameliorates adipose tissue inflammation through the Cathepsin G/Integrin/AKT pathway

Li, B., Guo, Y., Xiao, G., Guo, L., & Tang, Q. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101500 · Cited by 50

Constitutive and regulated expression and secretion of interferon-γ-inducible protein 10 (IP-10/CXCL10) in human adipocytes

Herder, C., Hauner, H., Kempf, K., Kolb, H., & Skurk, T. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803432 · Cited by 50

Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes

Sullivan, T. J., Miao, Z., Zhao, B. N., Ertl, L. S., Wang, Y., Krasinski, A., Walters, M. J., Powers, J. P., Dairaghi, D. J., Baumgart, T., et al. (2013) · Metabolism · doi:10.1016/j.metabol.2013.06.008 · Cited by 56

Hematological Disorders following Gastric Bypass Surgery: Emerging Concepts of the Interplay between Nutritional Deficiency and Inflammation

Chen, M., Krishnamurthy, A., Mohamed, A. R., & Green, R. (2013) · BioMed Research International · doi:10.1155/2013/205467 · Cited by 50

Monocyte Chemoattractant Protein‐1 in Obesity and Type 2 Diabetes. Insulin Sensitivity Study

Chacón, M. R., Fernández‐Real, J. M., Richart, C., Megía, A., Gómez, J. M., Miranda, M., Caubet, E., Pastor, R., Noguera, C. M., Vilarrasa, N., et al. (2007) · Obesity · doi:10.1038/oby.2007.578 · Cited by 51

Risk Factors for Preeclampsia in Women from Colombia: A Case-Control Study

Reyes, L. M., Garcia, R. G., Ruiz, S. L., Camacho, P. A., Ospina, M. B., Aroca, G., Accini, J., & López-Jaramillo, P. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041622 · Cited by 50

Oxidative Stress Regulates Adipocyte Apolipoprotein E and Suppresses Its Expression in Obesity

Espiritu, D. J. D., & Mazzone, T. (2008) · Diabetes · doi:10.2337/db08-0592 · Cited by 51

Impact of Physical Inactivity on Adipose Tissue Low-Grade Inflammation in First-Degree Relatives of Type 2 Diabetic Patients

Højbjerre, L., Sonne, M. P., Alibegovic, A. C., Nielsen, N. B., Dela, F., Vaag, A. A., Bruun, J. M., & Stallknecht, B. M. (2011) · Diabetes Care · doi:10.2337/dc11-0631 · Cited by 50

Function and Dysfunction of Adipose Tissue

Matafome, P. N., & Seiça, R. M. F. (2017) · Advances in neurobiology · doi:10.1007/978-3-319-63260-5_1 · Cited by 51

Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1–Dependent Manner

Josephrajan, A., Hertzel, A. V., Bohm, E. K., McBurney, M. W., Imai, S., Mashek, D. G., Kim, D., & Bernlohr, D. (2019) · Diabetes · doi:10.2337/db18-1367 · Cited by 50

Prediabetes is associated with abnormal circadian blood pressure variability

Gupta, A., Greenway, F. L., Cornélissen, G., Pan, W., & Franz Halberg, A. (2008) · Journal of Human Hypertension · doi:10.1038/jhh.2008.32 · Cited by 50

Modifying Effects of IL‐6 Polymorphisms on Body Size–Associated Breast Cancer Risk

Slattery, M. L., Curtin, K., Sweeney, C., Wolff, R. K., Baumgartner, R., Baumgartner, K. B., Giuliano, A. R., & Byers, T. (2008) · Obesity · doi:10.1038/oby.2007.44 · Cited by 47

The role of urotensin II in the metabolic syndrome

Ong, K. L., Wong, L. Y. F., & Cheung, B. M. Y. (2007) · Peptides · doi:10.1016/j.peptides.2007.06.003 · Cited by 50

From a glucocentric to a lipocentric approach towards metabolic syndrome

Mittra, S., Bansal, V. S., & Bhatnagar, P. K. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2008.01.006 · Cited by 48

Protein Array Reveals Differentially Expressed Proteins in Subcutaneous Adipose Tissue in Obesity

Škopková, M., Penesová, A., Sell, H., Rádiková, Ž., Vlček, M., Imrich, R., Koška, J., Ukropec, J., Eckel, J., Klimeś, I., et al. (2007) · Obesity · doi:10.1038/oby.2007.285 · Cited by 51

Comparison of Isotope-labeled Amino Acid Incorporation Rates (CILAIR) Provides a Quantitative Method to Study Tissue Secretomes

Roelofsen, H., Dijkstra, M., Weening, D., de Vries, M. P., Hoek, A., & Vonk, R. J. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m800254-mcp200 · Cited by 49

Inflammation, Atherosclerosis, and Aspects of Insulin Action

Bloomgarden, Z. T. (2005) · Diabetes Care · doi:10.2337/diacare.28.9.2312 · Cited by 48

Haplotypes in the urotensin II gene and urotensin II receptor gene are associated with insulin resistance and impaired glucose tolerance

Ong, K. L., Wong, L. Y. F., Man, Y. B., Leung, R. Y. H., Song, Y., Lam, K. S. L., & Cheung, B. M. Y. (2006) · Peptides · doi:10.1016/j.peptides.2006.02.008 · Cited by 49

Attenuation of inflammation and cellular stress‐related pathways maintains insulin sensitivity in obese type I interleukin‐1 receptor knockout mice on a high‐fat diet

de Roos, B., Rungapamestry, V., Ross, K., Rucklidge, G. J., Reid, M., Duncan, G., Horgan, G. W., Toomey, S., Browne, J. A., Loscher, C. E., et al. (2009) · PROTEOMICS · doi:10.1002/pmic.200800761 · Cited by 48

Non-alcoholic fatty liver disease: From insulin resistance to mitochondrial dysfunction

Herruzo, J. A. S., Ruiz, I. G., Carreras, M. P., & Muñoz-Yagüe, M. T. (2006) · Revista Española de Enfermedades Digestivas · doi:10.4321/s1130-01082006001100006 · Cited by 48

Targeting PGC-1α to control energy homeostasis

Wu, Z., & Boss, O. (2007) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.11.10.1329 · Cited by 50

Effect of a high-fat diet in development of colonic adenoma in an animal model

Zhu, Q. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i25.8119 · Cited by 48

Differential Effects of High-Fish Oil and High-Lard Diets on Cells and Cytokines Involved in the Inflammatory Process in Rat Insulin-Sensitive Tissues

Lionetti, L., Mollica, M. P., Sica, R., Donizzetti, I., Gifuni, G., Pignalosa, A., Cavaliere, G., & Putti, R. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15023040 · Cited by 49

Obesity-Induced Endothelial Dysfunction Is Prevented by Deficiency of P-Selectin Glycoprotein Ligand-1

Wang, H., Luo, W., Wang, J., Guo, C., Wang, X., Wolffe, S. L., Bodary, P. F., & Eitzman, D. T. (2012) · Diabetes · doi:10.2337/db12-0162 · Cited by 47

Prediabetes and prehypertension in disease free obese adults correlate with an exacerbated systemic proinflammatory milieu

Gupta, A., & Johnson, W. D. (2010) · Journal of Inflammation · doi:10.1186/1476-9255-7-36 · Cited by 47

Recent advances in orally administered cell-specific nanotherapeutics for inflammatory bowel disease

Si, X., Merlin, D., & Xiao, B. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i34.7718 · Cited by 48

Pro-resolving actions of SPM in adipose tissue biology

Clària, J., López‐Vicario, C., Rius, B., & Titos, E. (2017) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2017.03.004 · Cited by 49

Retinoic acid receptor-related orphan receptor α stimulates adipose tissue inflammation by modulating endoplasmic reticulum stress

Liu, Y., Chen, Y., Zhang, J., Liu, Y., Zhang, Y., & Su, Z. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.782391 · Cited by 48

The Beneficial Effect of Anthocyanidin‐Rich Vitis vinifera L. Grape Skin Extract on Metabolic Changes Induced by High‐Fat Diet in Mice Involves Antiinflammatory and Antioxidant Actions

da Costa, G. F., Santos, I. B., de Bem, G. F., Cordeiro, V. S. C., da Costa, C. A., de Carvalho, L. C. R. M., Ognibene, D. T., Resende, Â. C., & de Moura, R. S. (2017) · Phytotherapy Research · doi:10.1002/ptr.5898 · Cited by 53

The Targeted Impact of Flavones on Obesity-Induced Inflammation and the Potential Synergistic Role in Cancer and the Gut Microbiota

Sudhakaran, M., & Doseff, A. I. (2020) · Molecules · doi:10.3390/molecules25112477 · Cited by 49

Long term effects of high fat and sucrose diets on obesity and lymphocyte proliferation in mice

Sato‐Mito, N., Suzui, M., Yoshino, H., Kaburagi, T., & Sato, K. (2009) · The journal of nutrition health & aging · doi:10.1007/s12603-009-0170-2 · Cited by 48

Visceral adipose tissue: emerging role of gluco‐ and mineralocorticoid hormones in the setting of cardiometabolic alterations

Boscaro, M., Giacchetti, G., & Ronconi, V. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06597.x · Cited by 49

Effects of obesity, physical activity, and cardiorespiratory fitness on blood pressure, inflammation, and insulin resistance in the National Health and Nutrition Survey 1999–2002

Lin, C., Chen, P., Kuo, H.-K., Lin, L., Lin, J.-W., & Hwang, J. (2009) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2009.06.005 · Cited by 48

Potential Clinical Implications of the Urotensin II Receptor Antagonists

Tsoukas, P., Kane, É., & Giaid, A. (2011) · Frontiers in Pharmacology · doi:10.3389/fphar.2011.00038 · Cited by 47

Adiponectin Protein Exists in Aortic Endothelial Cells

Komura, N., Maeda, N., Mori, T., Kihara, S., Nakatsuji, H., Hirata, A., Tochino, Y., Funahashi, T., & Shimomura, I. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071271 · Cited by 47

Association between Change in Body Composition and Change in Inflammatory Markers: An 11-Year Follow-Up in the Whitehall II Study

Fransson, E. I., Batty, G. D., Tabák, Á. G., Brunner, E. J., Meena Kumari, B., Shipley, M. J., Singh‐Manoux, A., & Mika Kivimaki, B. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0730 · Cited by 47

Obesity-metabolic derangement preserves hemodynamics but promotes intrarenal adiposity and macrophage infiltration in swine renovascular disease

Zhang, X., Li, Z.-L., Woollard, J. R., Eirin, A., Ebrahimi, B., Crane, J. A., Zhu, X.-Y., Pawar, A. S., Krier, J. D., Jordan, K. L., et al. (2013) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00043.2013 · Cited by 47

Responsiveness to curcumin intervention is associated with reduced aortic stiffness in young, obese men with higher initial stiffness

Campbell, M. S., Berrones, A. J., Krishnakumar, I. M., Charnigo, R. J., Westgate, P. M., & Fleenor, B. S. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.12.013 · Cited by 47

Silybum marianum oil attenuates hepatic steatosis and oxidative stress in high fat diet-fed mice

Zhu, S. Y., Jiang, N., Yang, J., Tu, J., Zhou, Y. H., Xiao, X., & Dong, Y. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.01.144 · Cited by 47

Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration

Wang, L., Wang, Y., Zhang, C., Li, J., Meng, Y., Dou, M., Noguchi, C. T., & Di, L. (2018) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.118.311363 · Cited by 47

Serum amyloid A3 expression is stimulated by dexamethasone and interleukin-6 in 3T3-L1 adipocytes

Faßhauer, M., Klein, J. C., Kralisch, S., Klier, M., Lössner, U., Blüher, M., & Paschke, R. (2004) · Journal of Endocrinology · doi:10.1677/joe.1.05699 · Cited by 46

Impact of treating the metabolic syndrome on chronic kidney disease

Agrawal, V., Shah, A., Rice, C., Franklin, B. A., & McCullough, P. A. (2009) · Nature Reviews Nephrology · doi:10.1038/nrneph.2009.114 · Cited by 62

Use of nonsteroidal anti-inflammatory drugs and reduced breast cancer risk among overweight women

Cui, Y., Deming-Halverson, S. L., Shrubsole, M. J., Beeghly-Fadiel, A. C., Cai, H., Fair, A. M., Shu, X., & Zheng, W. (2014) · Breast Cancer Research and Treatment · doi:10.1007/s10549-014-3030-7 · Cited by 46

Obesity Programs Macrophages to Support Cancer Progression

Singh, A., Mayengbam, S. S., Yaduvanshi, H., Wani, M. R., & Bhat, M. K. (2022) · Cancer Research · doi:10.1158/0008-5472.can-22-1257 · Cited by 49

Modulation of metabolic syndrome‐related inflammation by cocoa

Gu, Y., & Lambert, J. D. (2013) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200837 · Cited by 47

Omega-3-derived mediators counteract obesity-induced adipose tissue inflammation

Titos, E., & Clària, J. (2013) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2013.05.003 · Cited by 51

Polycystic Ovary Syndrome as a systemic disease with multiple molecular pathways: a narrative review

Carvalho, L. M. L., dos Reis, F. M., Cândido, A. L., Nunes, F. F. C., Ferreira, C. N., & Gomes, K. B. (2018) · Endocrine Regulations · doi:10.2478/enr-2018-0026 · Cited by 48

Ghrelin receptor regulates HFCS-induced adipose inflammation and insulin resistance

Ma, X., Lin, L., Yue, J., Pradhan, G., Qin, G., Minze, L. J., Wu, H., Sheikh‐Hamad, D., Smith, C. W., & Sun, Y. (2013) · Nutrition and Diabetes · doi:10.1038/nutd.2013.41 · Cited by 46

A potential association between obesity and reduced effectiveness of COVID‐19 vaccine‐induced neutralizing humoral immunity

Faizo, A. A., Qashqari, F. S., El-Kafrawy, S. A., Barasheed, O., Almashjary, M. N., Alfelali, M., Bawazir, A. A., Albarakati, B. M., Khayyat, S. A., Hassan, A. M., et al. (2022) · Journal of Medical Virology · doi:10.1002/jmv.28130 · Cited by 46

Insulin, leptin, and adiponectin receptors in colon: regulation relative to differing body adiposity independent of diet and in response to dimethylhydrazine

Drew, J. E., Farquharson, A. J., Padidar, S., Duthie, G. G., Mercer, J. G., Arthur, J. R., Morrice, P. C., & Barrera, L. N. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00231.2007 · Cited by 45

Circulating Markers of Inflammation and Their Link to Indices of Adiposity

Browning, L. M., Krebs, J. D., Magee, E. C., Frühbeck, G., & Jebb, S. A. (2008) · Obesity Facts · doi:10.1159/000169832 · Cited by 45

Incremental Predictive Value of Serum AST-to-ALT Ratio for Incident Metabolic Syndrome: The ARIRANG Study

Yadav, D., Choi, E. H., Ahn, S. V., Baik, S. K., Cho, Y. Z., Koh, S. B., Huh, J. H., Chang, Y., Sung, K., & Kim, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161304 · Cited by 45

The Adipose Tissue as an Endocrine Organ – A Nephrologists’ Perspective

Chudek, J. T., Adamczak, M., Nieszporek, T., & Więcek, A. (2006) · KARGER eBooks · doi:10.1159/000095320 · Cited by 46

Metabolic Syndrome and Serum Liver Enzymes Level at Patients with Type 2 Diabetes Mellitus

Musić, M., Dervišević, A., Pepic, E., Lepara, O., Fajkić, A., Buturović, B. A. –., & Tuna, E. (2015) · Medical Archives · doi:10.5455/medarh.2015.69.251-255 · Cited by 45

Electronic health technology for the assessment of physical activity and eating habits in children and adolescents with overweight and obesity IDA

Schiel, R., Kaps, A., & Bieber, G. (2011) · Appetite · doi:10.1016/j.appet.2011.11.021 · Cited by 45

Insulin resistance is not related to plasma homocysteine concentration in healthy premenopausal women

Tanrıkulu-Kılıç, F., Bekpınar, S., Ünlüçerçi, Y., & Orhan, Y. (2006) · Physiological Research · doi:10.33549/physiolres.930745 · Cited by 45

Surfactant Protein D of the Innate Immune Defence is Inversely Associated with Human Obesity and SP‐D Deficiency Infers Increased Body Weight in Mice

Sørensen, G. L., Hjelmborg, J., Leth‐Larsen, R., Schmidt, V., Fenger, M., Poulain, F. R., Hawgood, S. B., Sørensen, G. L., Kyvik, K. O., & Holmskov, U. (2006) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.2006.01853.x · Cited by 45

Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes

Chang, H.-P., Wang, M.-L., Hsu, C.-Y., Liu, M.-E., Chan, M.-H., & Chen, Y.-H. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.12 · Cited by 46

Monomeric Tartrate Resistant Acid Phosphatase Induces Insulin Sensitive Obesity

Lång, P., van Harmelen, V., Rydén, M., Kaaman, M., Parini, P., Carneheim, C., Cassady, A. I., Hume, D. A., Andersson, G. N., & Arner, P. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001713 · Cited by 45

Elevated soluble ICAM‐1 levels induce immune deficiency and increase adiposity in mice

Wang, H., Babic, A. M., Mitchell, H. A., Liu, K., & Wagner, D. D. (2005) · The FASEB Journal · doi:10.1096/fj.04-3094fje · Cited by 45

Obesity and Dyslipidemia

Franssen, R., Monajemi, H., Stroes, E. S. G., & Kastelein, J. J. P. (2008) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2008.06.003 · Cited by 45

Specialized Perinodal Fat Fuels and Fashions Immunity

Knight, S. C. (2008) · Immunity · doi:10.1016/j.immuni.2008.01.003 · Cited by 45

Comparison of Gene Transcription between Subcutaneous and Visceral Adipose Tissue in Chinese Adults

Zha, J., Di, W. J., Zhu, T., Xie, Y., Yu, J., Liu, J., Chen, P., & Ding, G. (2009) · Endocrine Journal · doi:10.1507/endocrj.k09e-091 · Cited by 44

Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor α

Takahashi, H., Goto, T., Yamazaki, Y., Kamakari, K., Hirata, M., Suzuki, H., Shibata, D., Nakata, R., Inoue, H., Takahashi, N., et al. (2014) · Journal of Lipid Research · doi:10.1194/jlr.m052464 · Cited by 46

Obesity and Asthma

Beuther, D. A. (2009) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2009.05.002 · Cited by 44

C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer

Byun, J. S., & Gardner, K. L. (2013) · International Journal of Cell Biology · doi:10.1155/2013/647975 · Cited by 44

The impact of the Standard American Diet in rats: Effects on behavior, physiology and recovery from inflammatory injury

Totsch, S. K., Quinn, T. L., Strath, L. J., McMeekin, L. J., Cowell, R. M., Gower, B. A., & Sorge, R. E. (2017) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2017.08.009 · Cited by 46

Lipid metabolism, inflammation, and foam cell formation in health and metabolic disorders: targeting mTORC1

Cheon, S. Y., & Cho, K. (2021) · Journal of Molecular Medicine · doi:10.1007/s00109-021-02117-8 · Cited by 45

Cytokine release from adipose tissue of nonobese individuals

Sopasakis, V. R., Nagaev, I., & Smith, U. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803002 · Cited by 44

Developing dendritic cells become ‘lacy’ cells packed with fat and glycogen

Maroof, A., English, N. R., Bedford, P. A., Gabrilovich, D. I., & Knight, S. C. (2005) · Immunology · doi:10.1111/j.1365-2567.2005.02181.x · Cited by 44

Role of adipocytokines in metabolism and disease

Frühbeck, G., & Salvador, J. (2004) · Nutrition Research · doi:10.1016/j.nutres.2004.07.002 · Cited by 42

Metabolic Syndrome Pathophysiology

Das, U. N. (2010) · Wiley eBooks · doi:10.1002/9780813820637 · Cited by 44

Insulin and its role in chronic kidney disease

MAK, R. H. K. (2007) · Pediatric Nephrology · doi:10.1007/s00467-007-0611-2 · Cited by 42

Dietary Saponins of Sea Cucumber Ameliorate Obesity, Hepatic Steatosis, and Glucose Intolerance in High-Fat Diet–Fed Mice

Hu, X., Li, Z., Xue, Y., Xu, J., Xue, C., Wang, J., & Wang, Y. (2012) · Journal of Medicinal Food · doi:10.1089/jmf.2011.2042 · Cited by 43

A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome

Chu, S.-L., Fu, H., Yang, J.-X., Liu, G., Dou, P., Zhang, L., Tu, P., & Wang, X. (2011) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-011-0781-4 · Cited by 43

N-Acetylcysteine Supplementation Decreases Osteoclast Differentiation and Increases Bone Mass in Mice Fed a High-Fat Diet

Cao, J., & Picklo, M. J. (2013) · Journal of Nutrition · doi:10.3945/jn.113.185397 · Cited by 46

Ginsenoside Rb1 inhibits free fatty acids-induced oxidative stress and inflammation in 3T3-L1 adipocytes

Wang, M., Chen, Y., Xiong, Z., Yu, S., Zhou, B., Ling, Y., Zheng, Z., Shi, G., Wu, Y., & Qian, X. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7710 · Cited by 43

Role of wnt5a in Metabolic Inflammation in Humans

Relling, I., Akcay, G., Fangmann, D., Knappe, C., Schulte, D. M., Hartmann, K., Müller, N., Türk, K., Dempfle, A., Franke, A., et al. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-01007 · Cited by 44

Association between C-Reactive Protein and Metabolic Syndrome in Korean Adults

Song, Y., Yang, S. K., Kim, J., & Lee, D. (2018) · Korean Journal of Family Medicine · doi:10.4082/kjfm.17.0075 · Cited by 43

Effect of Weight Loss on High‐Molecular Weight Adiponectin in Obese Children

Martos‐Moreno, G. Á., Barrios, V., Martínez, G., Hawkins, F. G., & Argente, J. (2010) · Obesity · doi:10.1038/oby.2010.68 · Cited by 41

Obesity-associated cancer: an immunological perspective

Conroy, M. J., Dunne, M. R., Donohoe, C. L., & Reynolds, J. V. (2015) · Proceedings of The Nutrition Society · doi:10.1017/s0029665115004176 · Cited by 44

Relevance of omental pericellular adipose tissue collagen in the pathophysiology of human abdominal obesity and related cardiometabolic risk

Michaud, A., Tordjman, J., Pelletier, M., Liu, Y., Laforest, S., Noël, S., Naour, G. L., Bouchard, C., Clément, K., & Tchernof, A. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.173 · Cited by 45

CTLA-4Ig immunotherapy of obesity-induced insulin resistance by manipulation of macrophage polarization in adipose tissues

Fujii, M., Inoguchi, T., Batchuluun, B., Sugiyama, N., Kobayashi, K., Sonoda, N., & Takayanagi, R. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.07.034 · Cited by 42

AIMing at Metabolic Syndrome - Towards the Development of Novel Therapies for Metabolic Diseases via Apoptosis Inhibitor of Macrophage (AIM) -

Miyazaki, T., Kurokawa, J., & Arai, S. (2011) · Circulation Journal · doi:10.1253/circj.cj-11-0891 · Cited by 41

Differential effects of high fat diet and diet-induced obesity on skeletal acquisition in female C57BL/6J vs. FVB/NJ Mice

Devlin, M. J., Robbins, A. E., Cosman, M. N., Moursi, C., Cloutier, A. M., Louis, L. D., Vliet, M. V., Conlon, C., & Bouxsein, M. (2018) · Bone Reports · doi:10.1016/j.bonr.2018.04.003 · Cited by 43

Relationship between epicardial adipose tissue adipocyte size and MCP-1 expression

Eiras-Penas, S., Teijeira‐Fernández, E., Salgado‐Somoza, A., Couso, E., García‐Caballero, T., Sierra, J., & González‐Juanatey, J. R. (2010) · Cytokine · doi:10.1016/j.cyto.2010.05.009 · Cited by 42

Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients

Cardellini, M., Marini, M. A., Frontoni, S., Hribal, M. L., Andreozzi, F., Perticone, F., Federici, M., Lauro, D., & Sesti, G. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00291.2006 · Cited by 42

Plasma cytokines, glomerular filtration rate and adipose tissue cytokines gene expression in chronic kidney disease (CKD) patients

Spoto, B., Leonardis, D., Parlongo, R. M., Pizzini, P., Pisano, A., Cutrupi, S., Testa, A., Tripepi, G. L., Zoccali, C., & Mallamaci, F. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2011.01.005 · Cited by 42

Adipose Tissue Has Anti‐Inflammatory Properties

Dayer, J.-M., Chicheportiche, R., Juge-Aubry, C. E., & Meier, C. A. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1351.043 · Cited by 42

TNF-alpha Is Required for the Attraction of Mesenchymal Precursors to White Adipose Tissue in Ob/ob Mice

Gálvez, B. G., Martín, N. S., & Rodríguez, C. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004444 · Cited by 41

Oral health behaviors and metabolic syndrome: the 2008–2010 Korean National Health and Nutrition Examination Survey

Kim, Y., Kim, D., Lim, K. S., Ko, B.-J., Han, B.-D., Nam, G. E., Park, Y. G., Han, K., Kim, J., & Cho, K.-H. (2013) · Clinical Oral Investigations · doi:10.1007/s00784-013-1112-2 · Cited by 40

Differential Effects of Grape Powder and Its Extract on Glucose Tolerance and Chronic Inflammation in High-Fat-Fed Obese Mice

Chuang, C., Shen, W., Chen, H., Xie, G., Jia, W. P., Chung, S., & McIntosh, M. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf3028107 · Cited by 41

Endocannabinoid signaling and energy metabolism: A target for dietary intervention

Kim, J. J., Li, Y., & Watkins, B. A. (2011) · Nutrition · doi:10.1016/j.nut.2010.11.003 · Cited by 41

[New trends in macrophages, inflammation and adipose tissue].

Rico-Rosillo, M. G., & Vega-Robledo, G. B. (2012) · PubMed · Cited by 2

Review article: Is obesity an inflammatory illness? Role of low‐grade inflammation and macrophage infiltration in human white adipose tissue

Cancello, R., & Clément, K. (2006) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2006.01004.x · Cited by 418

Papel do tecido adiposo e dos macrófagos no estado de inflamação crónica associada à obesidade: implicações clínicas.

Ramalho, R., & Guimarães, C. (2008) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · Cited by 5

Le tissu adipeux

Dalmas, É., Tordjman, J., Guerre-Millo, M., & Clément, K. (2011) · médecine/sciences · doi:10.1051/medsci/20112711016 · Cited by 17

Adipose Tissue Inflammation in Obesity

Poitou, C., Dalmas, É., & Clément, K. (2012) · Springer eBooks · doi:10.1007/978-2-8178-0343-2_20 · Cited by 2