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Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases
Open accessAbstract
Classic atopic dermatitis is complicated by asthma, allergic rhinitis, and food allergies, cumulatively referred to as atopic diseases. Recent discoveries of mutations in the filaggrin gene as predisposing factors for atopic diseases have refocused investigators' attention on epidermal barrier dysfunction as a causative mechanism. The skin's barrier function has three elements: the stratum corneum (air-liquid barrier), tight junctions (liquid-liquid barrier), and the Langerhans cell network (immunological barrier). Clarification of the molecular events underpinning epidermal barrier function and dysfunction should lead to a better understanding of the pathophysiological mechanisms of atopic diseases.
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“Either too much or too little EGFR activity at TJs will impair barrier function and alter cytokine expression, both of which contribute to skin inflammatory skin diseases3 as well as skin cancer54.”
From E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning (2017) · cites this paper as [3]
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“Perturbed barrier function is critical for the development of not only atopic dermatitis but also other allergic disorders, namely, atopic march [8,9,10,11].”
From Antioxidant Artemisia princeps Extract Enhances the Expression of Filaggrin and Loricrin via the AHR/OVOL1 Pathway (2017) · cites this paper as [9]
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Cites
Williams, H. C., Leung, D. Y. M., Thestrup‐Pedersen, K., & David, T. J. (2000) · Cited by 4,597
Unravelling the pathogenesis of inflammatory bowel disease
Xavier, R. J., & Podolsky, D. K. (2007) · Nature · doi:10.1038/nature06005 · Cited by 4,364
Intestinal mucosal barrier function in health and disease
Turner, J. R. (2009) · Nature reviews. Immunology · doi:10.1038/nri2653 · Cited by 3,952
Palmer, C. N. A., Irvine, A. D., Terron-Kwiatkowski, A., Zhao, Y., Liao, H., Lee, S. P., Goudie, D. R., Sandilands, A., Campbell, L. E., Smith, F. J. D., et al. (2006) · Nature Genetics · doi:10.1038/ng1767 · Cited by 2,978
Multifunctional strands in tight junctions
Tsukita, S., Furuse, M., & Itoh, M. (2001) · Nature reviews. Molecular cell biology · doi:10.1038/35067088 · Cited by 2,578
Rescigno, M., Urbano, M., Valzasina, B., Francolini, M., Rotta, G., Bonasio, R., Granucci, F., Kraehenbuhl, J.-P., & Ricciardi‐Castagnoli, P. (2001) · Nature Immunology · doi:10.1038/86373 · Cited by 2,554
Bieber, T. (2008) · New England Journal of Medicine · doi:10.1056/nejmra074081 · Cited by 1,780
The cornified envelope: a model of cell death in the skin
Candi, E., Schmidt, R., & Melino, G. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1619 · Cited by 1,776
CX 3 CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance
Niess, J. H., Brand, S., Gu, X., Landsman, L., Jung, S., McCormick, B. A., Vyas, J. M., Boes, M. L., Ploegh, H. L., Fox, J. G., et al. (2005) · Science · doi:10.1126/science.1102901 · Cited by 1,609
Claudin-based tight junctions are crucial for the mammalian epidermal barrier
Furuse, M., Hata, M., Furuse, K., Yoshida, Y., Haratake, A., Sugitani, Y., Noda, T., Kubo, A., & Tsukita, S. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200110122 · Cited by 1,512
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Kobayashi, T., Glatz, M., Horiuchi, K., Kawasaki, H., Akiyama, H., Kaplan, D. H., Kong, H. H., Amagai, M., & Nagao, K. (2015) · Immunity · doi:10.1016/j.immuni.2015.03.014 · Cited by 566
Self-citationToward a new generation of smart skins
Someya, T., & Amagai, M. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0079-1 · Cited by 499
Self-citationSong, H., Yoo, Y., Hwang, J., Na, Y.-C., & Kim, H. S. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.08.021 · Cited by 416
Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis
Thyssen, J. P., & Kežić, S. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.06.014 · Cited by 411
The epithelial immune microenvironment (EIME) in atopic dermatitis and psoriasis
Dainichi, T., Kitoh, A., Otsuka, A., Nakajima, S., Nomura, T., Kaplan, D. H., & Kabashima, K. (2018) · Nature Immunology · doi:10.1038/s41590-018-0256-2 · Cited by 393
Nanoparticles skin absorption: New aspects for a safety profile evaluation
Larese Filon, F., Mauro, M., Adami, G., Bovenzi, M., & Crosera, M. (2015) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2015.05.005 · Cited by 390
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Ansary, T. M., Hossain, M. R., Kamiya, K., Komine, M., & Ohtsuki, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083974 · Cited by 393
Increasing Comorbidities Suggest that Atopic Dermatitis Is a Systemic Disorder
Brunner, P. M., Silverberg, J. I., Guttman‐Yassky, E., Paller, A. S., Kabashima, K., Amagai, M., Luger, T. A., Deleuran, M. S., Werfel, T., Eyerich, K., et al. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.08.022 · Cited by 382
Self-citationDissecting the formation, structure and barrier function of the stratum corneum
Matsui, T., & Amagai, M. (2015) · International Immunology · doi:10.1093/intimm/dxv013 · Cited by 368
Self-citationCytokinocytes: the diverse contribution of keratinocytes to immune responses in skin
Jiang, Y., Tsoi, L. C., Billi, A. C., Ward, N. L., Harms, P. W., Zeng, C., Maverakis, E., Kahlenberg, J. M., & Gudjonsson, J. E. (2020) · JCI Insight · doi:10.1172/jci.insight.142067 · Cited by 370
Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting
Samuelov, L., Sarig, O., Harmon, R. M., Rapaport, D., Ishida‐Yamamoto, A., Isakov, O., Koetsier, J. L., Gat, A., Goldberg, I., Bergman, R., et al. (2013) · Nature Genetics · doi:10.1038/ng.2739 · Cited by 336
Uberoi, A., Bartow‐McKenney, C., Zheng, Q., Flowers, L. J., Campbell, A. E., Knight, S. A. B., Chan, N., Wei, M. H., Lovins, V. M., Bugayev, J., et al. (2021) · Cell Host & Microbe · doi:10.1016/j.chom.2021.05.011 · Cited by 328
Ahlström, M. G., Thyssen, J. P., Wennervaldt, M., Menné, T., & Johansen, J. D. (2019) · Contact Dermatitis · doi:10.1111/cod.13327 · Cited by 315
Noti, M., Kim, B., Siracusa, M. C., Rak, G. D., Kubo, M., Moghaddam, A. E., Sattentau, Q. J., Comeau, M. R., Spergel, J. M., & Artis, D. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.01.021 · Cited by 302
Atopic dermatitis: the skin barrier and beyond
Tsakok, T., Woolf, R., Smith, C. H., Weidinger, S., & Flohr, C. (2018) · British Journal of Dermatology · doi:10.1111/bjd.16934 · Cited by 298
Han, H., Roan, F., & Ziegler, S. F. (2017) · Immunological Reviews · doi:10.1111/imr.12546 · Cited by 285
Sugita, K., Steer, C. A., Martínez-González, I., Altunbulakli, C., Morita, H., Castro-Giner, F., Kubo, T., Wawrzyniak, P., Rückert, B., Sudo, K., et al. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.02.038 · Cited by 277
Egawa, G., & Kabashima, K. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.06.002 · Cited by 265
Elias, P. M., & Wakefield, J. S. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.05.048 · Cited by 238
Kim, K. H. (2013) · Asia Pacific Allergy · doi:10.5415/apallergy.2013.3.2.79 · Cited by 246
Nakagawa, H., Nemoto, O., Igarashi, A., Saeki, H., Kaino, H., & Nagata, T. (2020) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2019.12.015 · Cited by 242
Wawrzyniak, P., Wawrzyniak, M., Wanke, K., Sokolowska, M., Bendelja, K., Rückert, B., Globinska, A., Jakiela, B., Kast, J. I., Idzko, M., et al. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.03.050 · Cited by 241
The cutaneous innate immune response in patients with atopic dermatitis
Kuo, I., Yoshida, T., Benedetto, A. D., & Beck, L. A. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.12.1563 · Cited by 241
The Pathobiology of Skin Aging
Russell-Goldman, E. E., & Murphy, G. F. (2020) · American Journal Of Pathology · doi:10.1016/j.ajpath.2020.03.007 · Cited by 224
Rübsam, M., Mertz, A. F., Kubo, A., Marg, S., Jüngst, C., Goranci-Buzhala, G., Schauss, A. C., Horsley, V., Dufresne, E. R., Moser, M., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01170-7 · Cited by 210
Self-citationThe Skin Barrier and Moisturization: Function, Disruption, and Mechanisms of Repair
Rajkumar, J., Chandan, N., Lio, P., & Shi, V. (2023) · Skin Pharmacology and Physiology · doi:10.1159/000534136 · Cited by 193
Tight junction‐related human diseases
Sawada, N. (2013) · Pathology International · doi:10.1111/pin.12021 · Cited by 177
Kuo, I., Carpenter-Mendini, A. B., Yoshida, T., McGirt, L. Y., Ivanov, A. I., Barnes, K. C., Gallo, R. L., Borkowski, A. W., Yamasaki, K., Leung, D. Y. M., et al. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.437 · Cited by 177
Roth, W., Kumar, V., Beer, H., Richter, M., Wohlenberg, C., Reuter, U., Thiering, S., Staratschek‐Jox, A., Hofmann, A., Kreusch, F., et al. (2012) · Journal of Cell Science · doi:10.1242/jcs.116574 · Cited by 160
Rübsam, M., Broussard, J. A., Wickström, S. A., Nekrasova, O. E., Green, K. J., & Niessen, C. M. (2017) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a029207 · Cited by 151
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Bergmann, M. M., Caubet, J., Boguniewicz, M., & Eigenmann, P. (2012) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2012.11.005 · Cited by 149
Yoshida, K., Kubo, A., Fujita, H., Yokouchi, M., Ishii, K., Kawasaki, H., Nomura, T., Shimizu, H., Kouyama, K., Ebihara, T., et al. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.08.001 · Cited by 145
Self-citationNakagawa, H., Nemoto, O., Igarashi, A., & Nagata, T. (2017) · British Journal of Dermatology · doi:10.1111/bjd.16014 · Cited by 145
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Jiao, Q., Zhi, L., You, B., Wang, G., Wu, N., & Jia, Y. (2024) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.16155 · Cited by 134
Zhu, T. H., Zhu, T. R., Tran, K. A., Sivamani, R. K., & Shi, V. Y. (2018) · British Journal of Dermatology · doi:10.1111/bjd.16734 · Cited by 133
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Kou, K., Okawa, T., Yamaguchi, Y., Ono, J., Inoue, Y., Kohno, M., Matsukura, S., Kambara, T., Ohta, S., Izuhara, K., et al. (2014) · British Journal of Dermatology · doi:10.1111/bjd.12943 · Cited by 125
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Yokouchi, M., Atsugi, T., van Logtestijn, M. D. A., Tanaka, R. J., Kajimura, M., Suematsu, M., Furuse, M., Amagai, M., & Kubo, A. (2016) · eLife · doi:10.7554/elife.19593 · Cited by 124
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Lee, H.-J., & Lee, S. H. (2014) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2014.6.4.276 · Cited by 123
Zuurveld, M., van Witzenburg, N. P., Garssen, J., Folkerts, G., Stahl, B., Land, B. V., & Willemsen, L. E. M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00801 · Cited by 126
Sano, Y., Masuda, K., Tamagawa‐Mineoka, R., Matsunaka, H., Murakami, Y., Yamashita, R., Morita, E., & Katoh, N. (2012) · Clinical & Experimental Immunology · doi:10.1111/cei.12021 · Cited by 121
Sasaki, T., Shiohama, A., Kubo, A., Kawasaki, H., Ishida‐Yamamoto, A., Yamada, T., Hachiya, T., Shimizu, A., Okano, H., Kudoh, J., et al. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.08.027 · Cited by 120
Self-citationEvaluation of immunoresponses and cytotoxicity from skin exposure to metallic nanoparticles
Wang, M., Lai, X., Shao, L., & Li, L. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s170745 · Cited by 116
Kaesler, S., Volz, T., Skabytska, Y., Köberle, M., Hein, U., Chen, K.-M., Guenova, E., Wölbing, F., Röcken, M., & Biedermann, T. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.02.017 · Cited by 115
Yoshida, K., Yokouchi, M., Nagao, K., Ishii, K., Amagai, M., & Kubo, A. (2013) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2013.04.021 · Cited by 115
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Yoon, J., Leyva-Castillo, J. M., Wang, G., Galand, C., Oyoshi, M. K., Kumar, L., Hoff, S., He, R., Chervonsky, A. V., Oppenheim, J. J., et al. (2016) · The Journal of Experimental Medicine · doi:10.1084/jem.20150376 · Cited by 101
Fujii, M. (2019) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b19-00088 · Cited by 107
Sargen, M. R., Hoffstad, O., & Margolis, D. J. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.274 · Cited by 99
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Natsuga, K. (2014) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a018218 · Cited by 84
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Deckers, J., Bosscher, K. D., Lambrecht, B. N., & Hammad, H. (2017) · Immunological Reviews · doi:10.1111/imr.12542 · Cited by 79
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Self-citationGuo, Y., Redmond, C. J., Leacock, K. A., Brovkina, M. V., Ji, S., Jaskula-Ranga, V., & Coulombe, P. A. (2020) · eLife · doi:10.7554/elife.53165 · Cited by 69
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Okano, J., Kojima, H., Katagi, M., Nakagawa, T., Nakae, Y., Terashima, T., Kurakane, T., Kubota, M., Maegawa, H., & Udagawa, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166215 · Cited by 69
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Siddique, M. I., Katas, H., Amin, M. C. I. M., Ng, S., Zulfakar, M. H., & Jamil, A. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.05.005 · Cited by 70
Deckers, J., Sichien, D., Plantinga, M., Moorleghem, J. V., Vanheerswynghels, M., Hoste, E., MALISSEN, B., Dombrowicz, D., Guilliams, M., Bosscher, K. D., et al. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.12.970 · Cited by 70
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Sakamoto, K., Jin, S., Goel, S., Jo, J., Voisin, B., Kim, D. Y., Nadella, V., Liang, H., Kobayashi, T., Huang, X., et al. (2021) · Immunity · doi:10.1016/j.immuni.2021.09.001 · Cited by 62
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Takahashi, S., Ishida, A., Kubo, A., Kawasaki, H., Ochiai, S., Nakayama, M., Koseki, H., Amagai, M., & Okada, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-44866-0 · Cited by 60
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Lee, H.-J., Yoon, N. Y., Lee, N. R., Jung, M., Kim, D. H., & Choi, E. H. (2014) · Experimental Dermatology · doi:10.1111/exd.12525 · Cited by 58
Wang, X., Jiang, X., Yu, X., Liu, H., Tao, Y., Jiang, G., & Hong, M. (2017) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13204 · Cited by 58
Lee, J.-O., Hwang, S.-H., Shen, T., Kim, J. H., You, L., Hu, W., & Cho, J. Y. (2020) · Journal of Ginseng Research · doi:10.1016/j.jgr.2020.12.003 · Cited by 57
Pople, P. V., & Singh, K. K. (2012) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2012.11.026 · Cited by 60
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Tang, L., Gao, J., Cao, X., Chen, L., Wang, H., & Ding, H. (2021) · Experimental Dermatology · doi:10.1111/exd.14464 · Cited by 54
Kim, T., Kim, S. H., Park, J., Choi, W., Sohn, M., Na, H. Y., Lee, M., Lee, J. W., Kim, S. M., Kim, D. Y., et al. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2017.11.003 · Cited by 53
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Kim, T., Kim, S. H., & Lee, M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms19010042 · Cited by 53
Kanoh, H., Ishitsuka, A., Fujine, E., Matsuhaba, S., Nakamura, M., Ito, H., Inagaki, N., Banno, Y., & Seishima, M. (2019) · Journal of Immunology Research · doi:10.1155/2019/3030268 · Cited by 53
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Metadata
- Authors
- Kubo, A., Nagao, K., & Amagai, M.
- Affiliations
- Keio University (JP)
- Corresponding author
- Amagai, Masayuki
- Venue
- Journal of Clinical Investigation
- Published
- 2012-02-01
- Volume
- 122
- Issue
- 2
- Pages
- 440-447
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC3266780
- OpenAlex
- W2157038335
- Cited by
- 378
- References
- 129
- Citations by year
- 2026: 13 · 2025: 20 · 2024: 21 · 2023: 21 · 2022: 25 · 2021: 24 · 2020: 28 · 2019: 26 · 2018: 21 · 2017: 32 · 2016: 30 · 2015: 26 · 2014: 41 · 2013: 34 · 2012: 16
- FWCI
- 7.54
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Investigation (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Keio University
- Ministry of Education, Culture, Sports, Science and Technology
- Japan Society for the Promotion of Science (22249044, 21229014)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Keywords
- skin barrier dysfunction, skin sensitization, atopic dermatitis, atopic diseases, filaggrin mutations, stratum corneum, tight junctions, asthma, allergic rhinitis, food allergy, skin barrier
- MeSH terms
- Filaggrin Proteins, Animals, Dermatitis, Atopic, Epidermis, Humans, Hypersensitivity, Immediate, Intermediate Filament Proteins, Mutation, Skin
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