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Cited by 320

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Major and minor depression in Alzheimer's disease: prevalence and impact

·1997·The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

One hundred nine outpatients with Alzheimer's disease (AD) were neuropsychiatrically evaluated and rated on standardized measures of depression, activities of daily living (ADL), nonmood behavioral disturbance, and burdensome events such as serious wandering, falls, and accidents. Distribution of depression scores revealed three patient groups: very few depressive symptoms (51%), minor depression (27%), and major depression (22%). Major depression was associated with substantially greater impairment in ADL, worse nonmood behavioral disturbance (such as aggression), and more frequent serious wandering, even after adjusting for severity of dementia or comorbid health problems. Minor depression was also associated with nonmood behavioral disturbance and wandering. The authors conclude that both major and minor depression are common in AD and produce considerable mood and nonmood morbidity affecting both patients and caregivers. Efforts are warranted to identify and treat depression in AD.

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Crossref · 10.1176/jnp.9.4.556

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Metadata

Venue
The Journal of Neuropsychiatry and Clinical Neurosciences
Published
1997-11-01
Volume
9
Issue
4
Pages
556-561
ISSN
  • 0895-0172 (ISSN-L)
  • 1545-7222
OpenAlex
W39182999
Cited by
320
References
1
FWCI
6.25
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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