Heart Failure With Preserved Ejection Fraction: Prevention and Management
Open accessAbstract
Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome that constitutes nearly half of all heart failure cases. Because of lack of effective pharmacological targets to improve outcomes, the emphasis of the management and prevention of HFpEF should be through control of risk factors. This review will use the framework proposed by the American Heart Association on 7 simple measures ("Life's Simple 7") that involves diet and lifestyle changes to achieve ideal cardiovascular health. These 7 measures include (1) smoking, (2) obesity, (3) exercise, (4) diet, (5) blood pressure, (6) cholesterol, and (7) glucose control, which can help control the most common comorbidities and risk factors associated with HFpEF, such as hypertension, diabetes, and obesity. Therefore, application of these 7 simple measures would be a patient-centered and cost-effective way of prevention and management of HFpEF.
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Benefit in HFpEF may be obtained through control of associated morbidities and risk factors, mainly by implementation of a healthy lifestyle including smoking cessation, weight reduction, exercise, and healthy diet.
“Benefit may be obtained through control of associated morbidities and risk factors, mainly by implementation of a healthy lifestyle including smoking cessation, weight reduction, exercise, and healthy diet [115].”
From Dysregulated epicardial adipose tissue as a risk factor and potential therapeutic target of heart failure with preserved ejection fraction in diabetes (2022) · cites this paper as [115]
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Toprak, Ö., Kurt, H., Sarı, Y., Şarkış, C., Us, H., & Kırık, A. (2017) · Kidney & Blood Pressure Research · doi:10.1159/000468530 · Cited by 29,769 · see citing works
McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Čelutkienė, J., Chioncel, O. D., et al. (2021) · PubMed · doi:10.1093/eurheartj/ehab670 · Cited by 19,618 · see citing works
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1504720 · Cited by 12,315 · see citing works
Ahmed, A., Jorna, T., & Bhandari, S. (2016) · The Nephron journals/Nephron journals · doi:10.1159/000447068 · Cited by 11,782 · see citing works
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G. F., Coats, A. J. S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw128 · Cited by 11,429 · see citing works
A Randomized Trial of Intensive versus Standard Blood-Pressure Control
The SPRINT Research Group (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1511939 · Cited by 6,325 · see citing works
A Clinical Trial of the Effects of Dietary Patterns on Blood Pressure
Appel, L. J., Moore, T. J., Obarzanek, E., Vollmer, W. M., Svetkey, L. P., Sacks, F. M., Bray, G. A., Vogt, T. M., Cutler, J. A., Windhauser, M. M., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704173361601 · Cited by 5,981 · see citing works
Lloyd-Jones, D. M., Hong, Y., Labarthe, D., Mozaffarian, D., Appel, L. J., Van Horn, L., Greenlund, K., Daniels, S., Nichol, G., Tomaselli, G. F., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192703 · Cited by 4,750 · see citing works
DeFronzo, R. A., & Ferrannini, E. (1991) · Diabetes Care · doi:10.2337/diacare.14.3.173 · Cited by 4,555 · see citing works
Trends in Prevalence and Outcome of Heart Failure with Preserved Ejection Fraction
Owan, T., Hodge, D. O., Herges, R. M., Jacobsen, S. J., Roger, V. L., & Redfield, M. M. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052256 · Cited by 4,191 · see citing works
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31829e8807 · Cited by 3,304 · see citing works
Inzucchi, S. E., Bergenstal, R. M., Buse, J. B., Diamant, M., Ferrannini, E., Nauck, M., Peters, A. L., Tsapas, A., Wender, R., & Matthews, D. R. (2015) · Diabetes Care · doi:10.2337/dc14-2441 · Cited by 3,066 · see citing works
Yusuf, S., Pfeffer, M. A., Swedberg, K., Granger, C. B., Held, P., McMurray, J. J., Michelson, E. L., Olofsson, B., & Östergren, J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14285-7 · Cited by 2,994 · see citing works
Spironolactone for heart failure with preserved ejection fraction
Pitt, B., Pfeffer, M. A., Assmann, S. F., Boineau, R., Anand, I. S., Claggett, B., Clausell, N., Desai, A. S., Diaz, R., Fleg, J. L., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1313731 · Cited by 2,809 · see citing works
Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes
Green, J. B., Bethel, M. A., Armstrong, P. W., Buse, J. B., Engel, S. S., Garg, J., Josse, R., Kaufman, K. D., Koglin, J., Korn, S., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1501352 · Cited by 2,577 · see citing works
O'Connor (2009) · doi:10.1001/jama.2009.454 · Cited by 2,173 · see citing works
Irbesartan in patients with heart failure and preserved ejection fraction
Massie, B. M., Carson, P. E., McMurray, J. J., Komajda, M., McKelvie, R., Zile, M. R., Anderson, S., Donovan, M., Iverson, E., Staiger, C., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0805450 · Cited by 1,960 · see citing works
Oxidative Stress and Diabetic Vascular Complications
Giugliano, D., Ceriello, A., & Paolisso, G. (1996) · Diabetes Care · doi:10.2337/diacare.19.3.257 · Cited by 1,938 · see citing works
The perindopril in elderly people with chronic heart failure (PEP-CHF) study
Cleland, J. G. F. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl250 · Cited by 1,502 · see citing works
Rosuvastatin in older patients with systolic heart failure
Kjekshus, J., Apetrei, E., Barrios, V., Böhm, M., Cleland, J. G. F., Cornel, J. H., Dunselman, P., Fonseca, C., Goudev, A., Grande, P., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa0706201 · Cited by 1,487 · see citing works
Lipotoxic heart disease in obese rats: Implications for human obesity
Zhou, Y.-T., Grayburn, P., Karim, A., Shimabukuro, M., Higa, M., Baetens, D., Orci, L., & Unger, R. H. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.4.1784 · Cited by 1,265 · see citing works
New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part I
Zile, M. R., & Brutsaert, D. L. (2002) · Circulation · doi:10.1161/hc1102.105289 · Cited by 1,183 · see citing works
Redfield, M. M., Chen, H. H., Borlaug, B. A., Semigran, M. J., Lee, K. L., Lewis, G. D., LeWinter, M. M., Rouleau, J. L., Bull, D. A., Mann, D. L., et al. (2013) · JAMA · doi:10.1001/jama.2013.2024 · Cited by 1,156 · see citing works
GISSI-HF investigators (2008) · The Lancet · doi:10.1016/s0140-6736(08)61240-4 · Cited by 1,106 · see citing works
Belardinelli, R., Georgiou, D., Cianci, G., & Purcaro, A. (1999) · Circulation · doi:10.1161/01.cir.99.9.1173 · Cited by 1,099 · see citing works
Kitzman, D. W., Brubaker, P., Morgan, T., Haykowsky, M., Hundley, G., Kraus, W. E., Eggebeen, J., & Nicklas, B. J. (2016) · JAMA · doi:10.1001/jama.2015.17346 · Cited by 921 · see citing works
Yancy, C. W., Jessup, M. L., Bozkurt, B., Butler, J., Casey, D. E., Colvin, M. M., Drazner, M. H., Filippatos, G. S., Fonarow, G. C., Givertz, M. M., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000435 · Cited by 899 · see citing works
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus
Salpeter, S. R., Greyber, E., Pasternak, G. A., & Salpeter (posthumous), E. E. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002967.pub4 · Cited by 893 · see citing works
Endothelial dysfunction — A major mediator of diabetic vascular disease
Sena, C. M., Pereira, A. M., & Seiça, R. M. F. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.08.006 · Cited by 796 · see citing works
Edelmann, F., Wachter, R., Schmidt, A. G., Kraigher‐Krainer, E., Colantonio, C., Kamke, W., Duvinage, A., Stahrenberg, R., Durstewitz, K., Löffler, M., et al. (2013) · JAMA · doi:10.1001/jama.2013.905 · Cited by 742 · see citing works
Flynn, K. E., Piña, I. L., Whellan, D. J., Lin, L., Blumenthal, J. A., Ellis, S. J., Fine, L. J., Howlett, J. G., Keteyian, S. J., Kitzman, D. W., et al. (2009) · JAMA · doi:10.1001/jama.2009.457 · Cited by 737 · see citing works
Scirica, B. M., Braunwald, E., Raz, I., Cavender, M. A., Morrow, D. A., Jarolim, P., Udell, J. A., Mosenzon, O., Im, K., Umez-Eronini, A. A., et al. (2014) · Circulation · doi:10.1161/circulationaha.114.010389 · Cited by 725 · see citing works
Yancy, C. W., Jessup, M. L., Bozkurt, B., Butler, J., Casey, D. E., Colvin, M. M., Drazner, M. H., Filippatos, G. S., Fonarow, G. C., Givertz, M. M., et al. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.05.011 · Cited by 614 · see citing works
Ahmed, A., Rich, M. W., Fleg, J. L., Zile, M. R., Young, J. B., Kitzman, D. W., Love, T. E., Aronow, W. S., Adams, K. F., & Gheorghiade, M. (2006) · Circulation · doi:10.1161/circulationaha.106.628347 · Cited by 605 · see citing works
Heart failure prevalence, incidence, and mortality in the elderly with diabetes
Bertoni, A. G., Hundley, W. G., Massing, M. W., Bonds, D. E., Burke, G. L., & Goff, D. C. (2004) · Diabetes Care · doi:10.2337/diacare.27.3.699 · Cited by 596 · see citing works
Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction
Redfield, M. M., Anstrom, K. J., Levine, J. A., Koepp, G. A., Borlaug, B. A., Chen, H. H., LeWinter, M. M., Joseph, S. M., Shah, S. J., Semigran, M. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1510774 · Cited by 547 · see citing works
From, A. M., Scott, C. G., & Chen, H. H. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.12.003 · Cited by 469 · see citing works
The relationship between cholesterol and survival in patients with chronic heart failure
Rauchhaus, M., Clark, A. L., Doehner, W., Davos, C. H., Bolger, A. P., Sharma, R. K., Coats, A. J. S., & Anker, S. D. (2003) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.07.016 · Cited by 444 · see citing works
Szczepaniak, L. S., Dobbins, R. L., Metzger, G. J., Sartoni‐D'Ambrosia, G., Arbique, D., Vongpatanasin, W., Unger, R. H., & Victor, R. G. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10372 · Cited by 441 · see citing works
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus
Salpeter, S. R., Greyber, E., Pasternak, G. A., & Salpeter, E. E. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002967.pub3 · Cited by 435 · see citing works
Exercise Training in Older Patients With Heart Failure and Preserved Ejection Fraction
Kitzman, D. W., Brubaker, P. H., Morgan, T. M., Stewart, K. P., & Little, W. C. (2010) · Circulation Heart Failure · doi:10.1161/circheartfailure.110.958785 · Cited by 410 · see citing works
Body Mass Index, Abdominal Fatness, and Heart Failure Incidence and Mortality
Aune, D., Sen, A., Norat, T., Janszky, I., Romundstad, P., Tonstad, S., & VATTEN, L. J. (2016) · Circulation · doi:10.1161/circulationaha.115.016801 · Cited by 381 · see citing works
Kitzman, D. W., Brubaker, P. H., Herrington, D. M., Morgan, T. M., Stewart, K. P., Hundley, W. G., Abdelhamed, A., & Haykowsky, M. J. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.04.033 · Cited by 369 · see citing works
Novel Metabolic Risk Factors for Incident Heart Failure and Their Relationship With Obesity
Bahrami, H., Bluemke, D. A., Kronmal, R. A., Bertoni, A. G., Lloyd‐Jones, D. M., Shahar, E., Szklo, M., & Lima, J. A. C. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.12.048 · Cited by 365 · see citing works
Thiazolidinediones and Cardiovascular Outcomes in Older Patients With Diabetes
Lipscombe, L. L., Gomes, T., Lévesque, L. E., Hux, J. E., Juurlink, D. N., & Alter, D. A. (2007) · JAMA · doi:10.1001/jama.298.22.2634 · Cited by 345 · see citing works
Pan, A., Wang, Y., Talaei, M., & Hu, F. B. (2015) · Circulation · doi:10.1161/circulationaha.115.017926 · Cited by 343 · see citing works
Palmieri, V., Bella, J. N., Arnett, D. K., Liu, J. E., Oberman, A., Schuck, M.-Y., Kitzman, D. W., Hopkins, P. N., Morgan, D., Rao, D. C., et al. (2001) · Circulation · doi:10.1161/01.cir.103.1.102 · Cited by 339 · see citing works
Solomon, S. D., Janardhanan, R., Verma, A. K., Bourgoun, M., Daley, W. L., Purkayastha, D., Lacourcière, Y., Hippler, S. E., Fields, H., Naqvi, T. Z., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60980-5 · Cited by 329 · see citing works
Dietary Magnesium Intake in Relation to Plasma Insulin Levels and Risk of Type 2 Diabetes in Women
Song, Y., Manson, J. E., Buring, J. E., & Liu, S. (2004) · Diabetes Care · doi:10.2337/diacare.27.1.59 · Cited by 302 · see citing works
Statin Therapy May Be Associated With Lower Mortality in Patients With Diastolic Heart Failure
Fukuta, H., Sane, D. C., Brucks, S., & Little, W. C. (2005) · Circulation · doi:10.1161/circulationaha.104.519876 · Cited by 294 · see citing works
Song, Y., He, K., Levitan, E. B., Manson, J. E., & Liu, S. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01852.x · Cited by 266 · see citing works
10-Year Exercise Training in Chronic Heart Failure
Belardinelli, R., Georgiou, D., Cianci, G., & Purcaro, A. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.06.036 · Cited by 263 · see citing works
Relationship Between Left Ventricular Structural and Metabolic Remodeling in Type 2 Diabetes
Levelt, E., Mahmod, M., Piechnik, S. K., Ariga, R., Francis, J. M., Rodgers, C. T., Clarke, W. T., Sabharwal, N. K., Schneider, J. E., Karamitsos, T. D., et al. (2015) · Diabetes · doi:10.2337/db15-0627 · Cited by 254 · see citing works
Ouwens, D. M., Diamant, M., Fodor, M., Habets, D. D. J., Pelsers, M. M. A. L., Hasnaoui, M. E., Dang, Z., van den Brom, C. E., Vlasblom, R., Rietdijk, A., et al. (2007) · Diabetologia · doi:10.1007/s00125-007-0735-8 · Cited by 233 · see citing works
Effects of Bariatric Surgery on Cardiovascular Function
Ashrafian, H., le Roux, C. W., Darzi, A. W., & Athanasiou, T. (2008) · Circulation · doi:10.1161/circulationaha.107.721027 · Cited by 228 · see citing works
Influence of diabetes mellitus on heart failure risk and outcome
Bauters, C., Lamblin, N., Fadden, E. P. M., BELLE, E. V., Millaire, A., & de Groote, P. (2003) · Cardiovascular Diabetology · doi:10.1186/1475-2840-2-1 · Cited by 213 · see citing works
Metformin Use and Mortality in Ambulatory Patients With Diabetes and Heart Failure
Aguilar, D. A., Chan, W., Bozkurt, B., Ramasubbu, K., & Deswal, A. M. (2010) · Circulation Heart Failure · doi:10.1161/circheartfailure.110.952556 · Cited by 204 · see citing works
Beneficial Cardiovascular Effects of Bariatric Surgical and Dietary Weight Loss in Obesity
Rider, O. J., Francis, J. M., Ali, M. K., Petersen, S. E., Robinson, M., Robson, M. D., Byrne, J. P., Clarke, K., & Neubauer, S. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.02.086 · Cited by 201 · see citing works
Longitudinal Tracking of Left Ventricular Mass Over the Adult Life Course
Lieb, W., Xanthakis, V., SULLIVAN, L. M., Aragam, J. R., Pencina, M. J., Larson, M. G., Benjamin, E. J., & Vasan, R. S. (2009) · Circulation · doi:10.1161/circulationaha.108.824243 · Cited by 201 · see citing works
Hummel, S. L., Seymour, E. M., Brook, R. D., Sheth, S. S., Ghosh, E., Zhu, S., Weder, A. B., Kovács, S. J., & Kolias, T. J. (2013) · Circulation: Heart Failure · doi:10.1161/circheartfailure.113.000481 · Cited by 190 · see citing works
RAnoLazIne for the Treatment of Diastolic Heart Failure in Patients With Preserved Ejection Fraction
Maier, L. S., Layug, B., Karwatowska‐Prokopczuk, E., Belardinelli, L., Lee, S. J., Sander, J., Lang, C., Wachter, R., Edelmann, F., Hasenfuss, G. P., et al. (2013) · JACC Heart Failure · doi:10.1016/j.jchf.2012.12.002 · Cited by 179 · see citing works
Suskin, N., Sheth, T., Negassa, A., & Yusuf, S. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01195-0 · Cited by 173 · see citing works
Udell, J. A., Bhatt, D. L., D, E. B. M., Cavender, M. A., Mosenzon, O., Steg, P. G., Davidson, J. A., Nicolau, J. C., Corbalan, R. L., Hirshberg, B., et al. (2014) · Diabetes Care · doi:10.2337/dc14-1850 · Cited by 163 · see citing works
Hummel, S. L., Seymour, E. M., Brook, R. D., Kolias, T. J., Sheth, S. S., Rosenblum, H. R., Wells, J. M., & Weder, A. B. (2012) · Hypertension · doi:10.1161/hypertensionaha.112.202705 · Cited by 161 · see citing works
Physical fitness and risk for heart failure and coronary artery disease
Berry, J. D., Pandey, A., Gao, A., Leonard, D., Farzaneh-Far, R., Ayers, C., DeFina, L., & Willis, B. (2013) · Circulation: Heart Failure · doi:10.1161/circheartfailure.112.000054 · Cited by 149 · see citing works
The epidemiology of left ventricular hypertrophy in type 2 diabetes mellitus
Dawson, A., Morris, A. D., & Struthers, A. D. (2005) · Diabetologia · doi:10.1007/s00125-005-1896-y · Cited by 137 · see citing works
Solomon, S. D., Verma, A. K., Desai, A. S., Hassanein, A. H., Izzo, J. L., Oparil, S., Lacourcière, Y., Lee, J., Seifu, Y., Hilkert, R. J., et al. (2009) · Hypertension · doi:10.1161/hypertensionaha.109.138529 · Cited by 127 · see citing works
Epidemiology of Heart Failure with Preserved Ejection Fraction
Dhingra, A., Garg, A., Kaur, S., Chopra, S., Batra, J. S., Pandey, A., Chaanine, A. H., & Agarwal, S. K. (2014) · Current Heart Failure Reports · doi:10.1007/s11897-014-0223-7 · Cited by 121 · see citing works
Impact of obesity on the risk of heart failure and survival after the onset of heart failure
Kenchaiah, S., Gaziano, J. M., & Vasan, R. S. (2004) · Medical Clinics of North America · doi:10.1016/j.mcna.2004.04.011 · Cited by 120 · see citing works
Samuelsson, A., Bollano, E., Mobini, R., Larsson, B.-M., Ömerovic, E., Fu, M. L. X., Waagstein, F., & Holmäng, A. B. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00974.2005 · Cited by 117 · see citing works
Jeong, E.-M., & Dudley, S. C. (2015) · Circulation Journal · doi:10.1253/circj.cj-15-0064 · Cited by 113 · see citing works
Chacko, S. A., Sul, J. H., Song, Y., Li, X., LeBlanc, J. F., You, Y., Butch, A. W., & Liu, S. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.002949 · Cited by 105 · see citing works
Association of Cardiorespiratory Fitness With Left Ventricular Remodeling and Diastolic Function
Brinker, S., Pandey, A., Ayers, C. R., Barlow, C. E., DeFina, L. F., Willis, B. L., Radford, N. B., Farzaneh‐Far, R., de Lemos, J. A., Drazner, M. H., et al. (2014) · JACC Heart Failure · doi:10.1016/j.jchf.2014.01.004 · Cited by 101 · see citing works
Aguilar, D., Deswal, A., Ramasubbu, K., Mann, D. L., & Bozkurt, B. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.09.041 · Cited by 96 · see citing works
Concomitant Diabetes Mellitus and Heart Failure
Dei, A., Fonarow, G. C., Gheorghiade, M., & Butler, J. (2014) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2014.09.002 · Cited by 92 · see citing works
Butler, J., Kalogeropoulos, A. P., Georgiopoulou, V. V., Bibbins-Domingo, K. B., Najjar, S. S., Sutton‐Tyrrell, K., Harris, T. B., Kritchevsky, S. B., Lloyd‐Jones, D. M., Newman, A. B., et al. (2011) · Heart · doi:10.1136/hrt.2011.225482 · Cited by 89 · see citing works
Left ventricular diastolic dysfunction in elderly hypertensives: results of the APROS-diadys study
Zanchetti, A., Cuspidi, C., Comarella, L., et al. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e3282eee9cf · Cited by 79 · see citing works
Cholesterol levels and in-hospital mortality in patients with acute decompensated heart failure
Horwich, T. B., Hernandez, A. F., Dai, D., Yancy, C. W., & Fonarow, G. C. (2008) · American Heart Journal · doi:10.1016/j.ahj.2008.07.004 · Cited by 78 · see citing works
Progressive Regression of Left Ventricular Hypertrophy Two Years after Bariatric Surgery
Algahim, M. F., Lux, T. R., Leichman, J. G., Boyer, A. F., Miller, C. C., Laing, S. T., Wilson, E. B., Scarborough, T. K., Yu, S. C., Snyder, B., et al. (2010) · The American Journal of Medicine · doi:10.1016/j.amjmed.2009.11.020 · Cited by 75 · see citing works
Heart Failure in North America
Blair, J. E., Huffman, M. D., & Shah, S. J. (2013) · Current Cardiology Reviews · doi:10.2174/1573403x11309020006 · Cited by 67 · see citing works
Prognostic Impact of Statin Use in Patients With Heart Failure and Preserved Ejection Fraction
Nochioka, K., Sakata, Y., Miyata, S., Miura, M., Takada, T., Tadaki, S., Ushigome, R., Yamauchi, T., Takahashi, J. A., Shimokawa, H., et al. (2015) · Circulation Journal · doi:10.1253/circj.cj-14-0865 · Cited by 65 · see citing works
Meta-Analysis of the Effect of Statins on Mortality in Patients With Preserved Ejection Fraction
Liu, G., Zheng, X., Xu, Y.-L., Ru, J., Hui, R., & Huang, X. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.12.023 · Cited by 63 · see citing works
Joshy, G., Korda, R., Attia, J., Liu, B. C., Bauman, A. E., & Banks, E. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.192 · Cited by 58 · see citing works
Total cholesterol levels and mortality risk in nonischemic systolic heart failure
Afsarmanesh, N., Horwich, T. B., & Fonarow, G. C. (2006) · American Heart Journal · doi:10.1016/j.ahj.2006.06.015 · Cited by 55 · see citing works
Lincoff, A. M., Wolski, K., Nicholls, S. J., & Nissen, S. E. (2007) · JAMA · doi:10.1001/jama.298.10.1180 · Cited by 52 · see citing works
Comorbidities and Differential Diagnosis in Heart Failure with Preserved Ejection Fraction
Campbell, R. T., & McMurray, J. J. V. (2014) · Heart Failure Clinics · doi:10.1016/j.hfc.2014.04.009 · Cited by 47 · see citing works
Cannon, M. V., Silljé, H. H. W., Sijbesma, J. W. A., Khan, M. A. F., Steffensen, K. R., van Gilst, W. H., & de Boer, R. A. (2015) · Diabetologia · doi:10.1007/s00125-015-3827-x · Cited by 44 · see citing works
Shah, R. V., Murthy, V. L., Abbasi, S. A., Eng, J., Wu, C. O., Ouyang, P., Kwong, R. Y. K., Goldfine, A. B., Bluemke, D. A., Lima, J. A. C., et al. (2014) · European Journal of Preventive Cardiology · doi:10.1177/2047487314541731 · Cited by 41 · see citing works
HbA1c and Heart Failure Risk Among Diabetic Patients
Zhao, W., Katzmarzyk, P. T., Horswell, R. L., Wang, Y., Johnson, J. L., & Hu, G. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-3325 · Cited by 41 · see citing works
Taveira, T. H., Ouellette, D., Gulum, A. H., Choudhary, G., Eaton, C. B., Liu, S., & Wu, W. (2016) · Circulation Heart Failure · doi:10.1161/circheartfailure.115.002698 · Cited by 37 · see citing works
Self-citationCocco, G., & Pandolfi, S. (2011) · The Journal of Clinical Hypertension · doi:10.1111/j.1751-7176.2010.00380.x · Cited by 32 · see citing works
Adipose tissue inflammation in diabetes and heart failure
Shimizu, I., Yoshida, Y., Katsuno, T., & Minamino, T. (2012) · Microbes and Infection · doi:10.1016/j.micinf.2012.10.012 · Cited by 30 · see citing works
Current Perspectives on Systemic Hypertension in Heart Failure with Preserved Ejection Fraction
Oktay, A. A., & Shah, S. J. (2014) · Current Cardiology Reports · doi:10.1007/s11886-014-0545-9 · Cited by 29 · see citing works
Treatment of diastolic dysfunction in hypertension
Ginelli, P., & Bella, J. N. (2012) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2012.04.016 · Cited by 25 · see citing works
Hypertension as an Underlying Factor in Heart Failure With Preserved Ejection Fraction
Volpe, M., McKelvie, R. S., & Drexler, H. (2010) · Journal of Clinical Hypertension · doi:10.1111/j.1751-7176.2009.00253.x · Cited by 21 · see citing works
Pharmacotherapy of Heart Failure with Preserved Ejection Fraction
Basaraba, J. E., & Barry, A. R. (2015) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1556 · Cited by 21 · see citing works
Acute effects of cigarette smoking on the cardiac diastolic functions
Alshehri, A., Azoz, A. M., Shaheen, H. A., et al. (2013) · Journal of the Saudi Heart Association · doi:10.1016/j.jsha.2013.03.003 · Cited by 16 · see citing works
Relationship Between Dietary Magnesium Intake and Incident Heart Failure Among Older Women: The WHI
Wu, W., Huang, M., Taveira, T. H., et al. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.013570 · Cited by 15 · see citing works
Self-citationThe Future Diagnosis of Heart Failure with Normal Ejection Fraction: Less Imaging, More Biomarkers?
Franssen, C., & Paulus, W. J. (2011) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfr106 · Cited by 14 · see citing works
Exercise Training in Patients With Heart Failure and Preserved Ejection Fraction
Keteyian, S. J. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.01.098 · Cited by 9 · see citing works
Low-density lipoprotein cholesterol lowering in the prevention of CHD: How low should we go?
Isley, W. L. (2006) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-006-0050-6 · Cited by 8 · see citing works
Ohte, N., & Little, W. C. (2015) · Circulation Journal · doi:10.1253/circj.cj-15-0016 · Cited by 7 · see citing works
Joffe, S., & Phillips, R. A. (2013) · Current Heart Failure Reports · doi:10.1007/s11897-013-0137-9 · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [41]41. Taveira TH, Ouellette D, Gulum A, Choudhary G, Eaton CB, Wu WCH. The relationship between dietary magnesium - intake and heart failure hospitalizations in African American adults: the Jackson Heart Study. Circulation . 2014;130:A19379.
Cited by
Sorted by citations
Salvatore, T., Galiero, R., Caturano, A., Vetrano, E., Rinaldi, L., Coviello, F., Di Martino, A., Albanese, G., Colantuoni, S., Medicamento, G., et al. (2022) · Biomolecules · doi:10.3390/biom12020176 · Cited by 62 · see citing works
Elsanhoury, A., Nelki, V., Kelle, S., Van Linthout, S., & Tschöpe, C. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.720690 · Cited by 51 · see citing works
- Authors
- Cilia, L., Saeed, A., Ganga, H. V., & Wu, W.-C.
- Affiliations
- United States Department of Veterans Affairs (US)
- Corresponding author
- Wu, Wen-Chih
- Venue
- American Journal of Lifestyle Medicine
- Publisher
- SAGE Publications
- Published
- 2017-02-01
- Volume
- 13
- Issue
- 2
- Pages
- 182-189
- ISSN
- 1559-8276 (ISSN-L)
- 1559-8284
- PMC
- PMC6378503
- OpenAlex
- W2593243969
- Cited by
- 18
- References
- 104
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 5 · 2021: 6 · 2020: 2
- FWCI
- 0.42
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- American Journal of Lifestyle Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Veterans Affairs
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- heart failure with preserved ejection fraction, Life's Simple 7, cardiovascular risk factors, lifestyle modification, smoking, obesity, physical activity, diet, blood pressure, cholesterol, glycemic control, hypertension, diabetes mellitus
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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