Cited by 111Inflammatory Bowel DiseaseGastrointestinal motility and disordersPediatric Pain Management Techniques

Pain management in patients with inflammatory bowel disease: insights for the clinician

Open access
Srinath, Arvind Iyengar, Walter, Chelsea, Newara, Melissa C., Szigethy, Eva M.·2012·Therapeutic Advances in Gastroenterology

Abstract

Abdominal pain is a common symptom in patients with inflammatory bowel disease (IBD) and has a profound negative impact on patients' lives. There are growing data suggesting that pain is variably related to the degree of active inflammation. Given the multifactorial etiologies underlying the pain, the treatment of abdominal pain in the IBD population is best accomplished by individualized plans. This review covers four clinically relevant categories of abdominal pain in patients with IBD, namely, inflammation, surgical complications, bacterial overgrowth, and neurobiological processes and how pain management can be addressed in each of these cases. The role of genetic factors, psychological factors, and psychosocial stress in pain perception and treatment will also be addressed. Lastly, psychosocial, pharmacological, and procedural pain management techniques will be discussed. An extensive review of the existing literature reveals a paucity of data regarding pain management specific to IBD. In addition, there is growing consensus suggesting a spectrum between IBD and irritable bowel syndrome (IBS) symptoms. Thus, this review for adult and pediatric clinicians also incorporates the literature for the treatment of functional abdominal pain and the clinical consensus from IBD and IBS experts on pharmacological, behavioral, and procedural methods to treat abdominal pain in this population.

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Crossref · 10.1177/1756283x12446158

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138 of 138 references verified0 citation errors · 0 not checkable

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Authors
Srinath, A. I., Walter, C., Newara, M. C., & Szigethy, E. M.
Affiliations
  • Children's Hospital of Pittsburgh (US)
  • University of Pittsburgh (US)
Venue
Therapeutic Advances in Gastroenterology
Published
2012-05-17
Volume
5
Issue
5
Pages
339-357
ISSN
  • 1756-283X (ISSN-L)
  • 1756-2848
OpenAlex
W2130155416
Cited by
111
References
138
Citations by year
2026: 4 · 2025: 3 · 2024: 6 · 2023: 6 · 2022: 10 · 2021: 10 · 2020: 16 · 2019: 14 · 2018: 7 · 2017: 7 · 2016: 4 · 2015: 10 · 2014: 10 · 2013: 3 · 2012: 1
FWCI
4.61
Type
journal article
Language
en
Open access
Locations
  • Therapeutic Advances in Gastroenterology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
University of Pittsburgh
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
Keywords
inflammatory bowel disease, abdominal pain, pain management, irritable bowel syndrome, bacterial overgrowth, surgical complications, psychological factors, psychosocial stress, functional abdominal pain, pharmacological pain management, behavioral pain management, procedural pain management

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