Cited by 872Health Policy Implementation ScienceHealth and Medical Research ImpactsInterdisciplinary Research and Collaboration

The DOI matches its Crossref record; 86 of the 87 references it cites were found in a registry or an index; none of the 41 sources its claims cite is checked for support yet.

Reenvisioning Clinical Science: Unifying the Discipline to Improve the Public Health

Open access

Abstract

We present a vision of clinical science, based on a conceptual framework of intervention development endorsed by the Delaware Project. This framework is grounded in an updated stage model that incorporates basic science questions of mechanisms into every stage of clinical science research. The vision presented is intended to unify various aspects of clinical science toward the common goal of developing maximally potent and implementable interventions, while unveiling new avenues of science in which basic and applied goals are of equally high importance. Training in this integrated, translational model may help students learn how to conduct research in every domain of clinical science and at each stage of intervention development. This vision aims to propel the field to fulfill the public health goal of producing implementable and effective treatment and prevention interventions.

Overview

Integrity signals

Registry

Crossref · 10.1177/2167702613497932

Cites

86 of 86 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

48 Own interpretation · 27 Not checked yet · 15 No basis given

Verify all 41 references — free account

Show all 41 claims

  • It may state two separate claims as one. 24
  • Probably not a substantial claim. 36
49 of 49
  • The paper relies on this without support.

    Complex treatments delivered with high fidelity in research settings by research therapists tend to lose strength when delivered in community settings by community providers.

    “Complex treatments administered with a high degree of fidelity in research settings with research therapists seem destined to weaken when implemented in community settings with community providers.”
  • The paper relies on this without support.

    Most clinical researchers were not trained in an integrative outlook and are too embedded in current clinical research pressures to change quickly.

    “Realistically, the large majority of clinical researchers, sympathetic as they may be to this sort of integrative vision, were not trained in this kind of outlook and are far too ensconced in the intense pressure of contemporary clinical research to change rapidly.”
  • The paper relies on this without support.

    Clinical science training currently produces excellent basic scientists, intervention developers and testers, effectiveness researchers, and implementation scientists.

    “Moreover, clinical science training now produces excellent basic scientists, intervention generators and testers, effectiveness researchers, and implementation scientists.”
  • The paper relies on this without support.

    It is generally considered necessary to demonstrate that an intervention is effective before moving to implementation and dissemination in real-world settings.

    “It is generally considered necessary to show that an intervention is effective before proceeding to implementation and dissemination in the real world.”
  • The paper relies on this without support.

    Basic science plays a major role in intervention development.

    “Basic science, considered to be Stage 0, plays a major role in intervention development.”
5 of 5

Claims other papers make about this one

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Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

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Citations

Cites

Show all 87 references

Research works printed but not linked: 3

  1. Institute of Medicine, 2006, Improving the quality of health care for mental and substance-use conditions: Quality chasm series
  2. Kringlen E., 1970, Seminars in Psychiatry, 2, 403
  3. McFall R. M., 2007, Psychological clinical science: Recent advances in theory and practice. Integrative perspectives in honor of Richard M. McFall, 363

Cited by

Sorted by citations

Items 101–124 of 124

Metadata

Authors
Onken, L. S., Carroll, K. M., Shoham, V., Cuthbert, B. N., & Riddle, M.
Affiliations
  • National Institute on Drug Abuse (US)
  • Yale University (US)
  • National Institute of Mental Health (US)
  • National Institute of Dental and Craniofacial Research (US)
Corresponding author
Onken, Lisa S.
Venue
Clinical Psychological Science
Published
2013-12-11
Volume
2
Issue
1
Pages
22-34
ISSN
  • 2167-7026 (ISSN-L)
  • 2167-7034
OpenAlex
W2013335489
Cited by
872
References
87
Citations by year
2026: 93 · 2025: 123 · 2024: 107 · 2023: 117 · 2022: 90 · 2021: 101 · 2020: 70 · 2019: 58 · 2018: 35 · 2017: 40 · 2016: 18 · 2015: 12 · 2014: 6 · 2013: 2
FWCI
22.82
Type
journal article
Language
en
Open access
Locations
  • Clinical Psychological Science (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (Z99 DA999999)
  • National Institute on Drug Abuse (P50DA009241, U10DA015831, R01DA015969)
Topics
  • Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
  • Social Sciences › Arts and Humanities › History and Philosophy of Science › Interdisciplinary Research and Collaboration
Keywords
clinical science, intervention development, stage model, intervention mechanisms, translational research, research training, implementation, prevention interventions, therapeutic interventions

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