Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Dixon, S. J., Lemberg, K. M., Lamprecht, M. R., Skouta, R., Zaitsev, E. M., Gleason, C. E., Patel, D. N., Bauer, A. J., Cantley, A. M., Yang, W. S., et al. (2012) · Cell · doi:10.1016/j.cell.2012.03.042 · Cited by 18,691 · see citing works

Regulation of Ferroptotic Cancer Cell Death by GPX4

Yang, W. S., SriRamaratnam, R., Welsch, M. E., Shimada, K., Skouta, R., Viswanathan, V. S., Cheah, J. H., Clemons, P. A., Shamji, A. F., Clish, C. B., et al. (2014) · Cell · doi:10.1016/j.cell.2013.12.010 · Cited by 7,713 · see citing works

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Friedmann Angeli, J. P., Schneider, M., Proneth, B., Tyurina, Y. Y., Tyurin, V. A., Hammond, V. J., Herbach, N., Aichler, M., Walch, A., Eggenhofer, E., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb3064 · Cited by 3,732 · see citing works

Ferroptosis: process and function

Xie, Y., Hou, W., Song, X., Yu, Y., Huang, J., Sun, X., Kang, R., & Tang, D. (2016) · Cell Death & Differentiation · doi:10.1038/cdd.2015.158 · Cited by 3,727 · see citing works

Monocyte recruitment during infection and inflammation

Shi, C., & Pamer, E. G. (2011) · Nature Reviews Immunology · doi:10.1038/nri3070 · Cited by 3,015 · see citing works

The ferritins: molecular properties, iron storage function and cellular regulation

Harrison, P. M., & Arosio, P. (1996) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(96)00022-9 · Cited by 2,667 · see citing works

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578 · see citing works

The role of iron and reactive oxygen species in cell death

Dixon, S. J., & Stockwell, B. R. (2014) · Nature Chemical Biology · doi:10.1038/nchembio.1416 · Cited by 2,381 · see citing works

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

Hashimoto, D., Chow, A., Noizat, C., Teo, P., Beasley, M. B., Leboeuf, M., Becker, C. D., See, P., Price, J., Lucas, D., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.04.004 · Cited by 2,311 · see citing works

Glutaminolysis and transferrin regulate ferroptosis

Gao, M., Monian, P., Quadri, N., Ramasamy, R., & Jiang, X. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.06.011 · Cited by 2,069 · see citing works

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

Yang, W. S., & Stockwell, B. R. (2008) · Chemistry & Biology · doi:10.1016/j.chembiol.2008.02.010 · Cited by 1,876 · see citing works

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

Kalyanaraman, B., Darley-Usmar, V. M., Davies, K. J. A., Dennery, P. A., Forman, H. J., Grisham, M. B., Mann, G. E., Moore, K. P., Roberts, L. J., & Ischiropoulos, H. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.030 · Cited by 1,795 · see citing works

Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

Tsou, C.-L., Peters, W., Si, Y., Slaymaker, S., Aslanian, A. M., Weisberg, S. P., Mack, M., & Charo, I. F. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29919 · Cited by 1,152 · see citing works

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

Skouta, R., Dixon, S. J., Wang, J., Dunn, D. E., Orman, M., Shimada, K., Rosenberg, P. A., Lo, D. C., Weinberg, J. M., Linkermann, A., et al. (2014) · Journal of the American Chemical Society · doi:10.1021/ja411006a · Cited by 1,146 · see citing works

Synchronized renal tubular cell death involves ferroptosis

Linkermann, A., Skouta, R., Himmerkus, N., Mulay, S. R., Dewitz, C., De Zen, F., Prokai, A., Zuchtriegel, G., Krombach, F., Welz, P.-S., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1415518111 · Cited by 1,126 · see citing works

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.

Boring, L., Gosling, J., Chensue, S. W., Kunkel, S. L., Farese, R. V., Broxmeyer, H. E., & Charo, I. F. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119798 · Cited by 1,096 · see citing works

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection

Matsushita, M., Freigang, S., Schneider, C., Conrad, M., Bornkamm, G. W., & Kopf, M. (2015) · Journal of Experimental Medicine · doi:10.1084/jem.20140857 · Cited by 672 · see citing works

Health Care–Associated Infection After Red Blood Cell Transfusion

Rohde, J. M., Dimcheff, D. E., Blumberg, N., Saint, S. K., Langa, K. M., Kuhn, L. E., Hickner, A., & Rogers, M. A. M. (2014) · JAMA · doi:10.1001/jama.2014.2726 · Cited by 610 · see citing works

Clinical consequences of red cell storage in the critically ill

Tinmouth, A. T., Fergusson, D. A., Yee, I. C., Hébert, P. C., & ABLE Investigators and the Canadian Critical Care Trials Group (2006) · Transfusion · doi:10.1111/j.1537-2995.2006.01026.x · Cited by 572 · see citing works

Age of transfused blood is an independent risk factor for postinjury multiple organ failure

Zallen, G. S., Offner, P. J., Moore, E. E., Blackwell, J., Ciesla, D. J., Gabriel, J., Denny, C., & Silliman, C. C. (1999) · The American Journal of Surgery · doi:10.1016/s0002-9610(99)00239-1 · Cited by 515 · see citing works

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

Chen, L., Hambright, W. S., Na, R., & Ran, Q. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.680090 · Cited by 498 · see citing works

Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation

Hod, E. A., Zhang, N., Sokol, S. A., Wojczyk, B. S., Francis, R. O., Ansaldi, D., Francis, K. P., Della-Latta, P., Whittier, S., Sheth, S., et al. (2010) · Blood · doi:10.1182/blood-2009-10-245001 · Cited by 485 · see citing works

Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis

Kohyama, M., Ise, W., Edelson, B. T., Wilker, P. R., Hildner, K., Mejia, C., Frazier, W. A., Murphy, T. L., & Murphy, K. M. (2009) · Nature · doi:10.1038/nature07472 · Cited by 479 · see citing works

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages

Haldar, M., Kohyama, M., So, A. Y.-L., KC, W., Wu, X., Briseño, C. G., Satpathy, A. T., Kretzer, N. M., Arase, H., Rajasekaran, N. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.01.069 · Cited by 431 · see citing works

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Theurl, I., Hilgendorf, I., Nairz, M., Tymoszuk, P., Haschka, D., Asshoff, M., He, S., Gerhardt, L. M. S., Holderried, T. A. W., Seifert, M., et al. (2016) · Nature Medicine · doi:10.1038/nm.4146 · Cited by 412 · see citing works

Glucose-6-Phosphate Dehydrogenase Deficiency

Luzzatto, L., Nannelli, C., & Notaro, R. (2016) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2015.11.006 · Cited by 405 · see citing works

Macrophages and Iron Metabolism

Soares, M. P., & Hamza, I. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.016 · Cited by 401 · see citing works

Influence of Storage on Red Blood Cell Rheological Properties

Berezina, T. L., Zaets, S. B., Morgan, C., Spillert, C. R., Kamiyama, M., Spolarics, Z., Deitch, E. A., & Machiedo, G. W. (2002) · Journal of Surgical Research · doi:10.1006/jsre.2001.6306 · Cited by 382 · see citing works

Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease

Carson, J. L., Brooks, M. M., Abbott, J. D., CHAITMAN, B. R., Kelsey, S. F., Triulzi, D. J., SRINIVAS, V. S., Menegus, M. A., Marroquin, O. C., Rao, S. V., et al. (2013) · American Heart Journal · doi:10.1016/j.ahj.2013.03.001 · Cited by 379 · see citing works

Association of mortality with age of blood transfused in septic ICU patients

Purdy, F. R., Tweeddale, M., & Merrick, P. M. (1997) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/bf03012772 · Cited by 358 · see citing works

Increased Rate of Infection Associated With Transfusion of Old Blood After Severe Injury

Offner, P. J. (2002) · Archives of Surgery · doi:10.1001/archsurg.137.6.711 · Cited by 334 · see citing works

Conditional macrophage ablation in transgenic mice expressing a Fas-based suicide gene

Burnett, S. H., Kershen, E. J., Zhang, J., Zeng, L., Straley, S. C., Kaplan, A. M., & Cohen, D. A. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0903442 · Cited by 307 · see citing works

Red cell changes during storage

Hess, J. R. (2010) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2010.05.009 · Cited by 290 · see citing works

Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution

Kovtunovych, G., Eckhaus, M., Ghosh, M. C., Ollivierre, H., & Rouault, T. A. (2010) · Blood · doi:10.1182/blood-2010-03-272138 · Cited by 273 · see citing works

Storage lesion: role of red blood cell breakdown

Kim‐Shapiro, D. B., Lee, J. S., & Gladwin, M. T. (2011) · Transfusion · doi:10.1111/j.1537-2995.2011.03100.x · Cited by 270 · see citing works

Additive Roles for MCP-1 and MCP-3 in CCR2-Mediated Recruitment of Inflammatory Monocytes during Listeria monocytogenes Infection

Jia, T., Serbina, N. V., Brandl, K., Zhong, M., Leiner, I. M., Charo, I. F., & Pamer, E. G. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.10.6846 · Cited by 256 · see citing works

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production

Fortes, G. B., Alves, L. S., de Oliveira, R., Dutra, F. F., Rodrigues, D., Fernandez, P. L., Souto-Padron, T., De Rosa, M. J., Kelliher, M., Golenbock, D., et al. (2012) · Blood · doi:10.1182/blood-2011-08-375303 · Cited by 246 · see citing works

Malaria impairs resistance to Salmonella through heme- and heme oxygenase–dependent dysfunctional granulocyte mobilization

Cunnington, A. J., de Souza, J. B., Walther, M., & Riley, E. M. (2012) · Nature Medicine · doi:10.1038/nm.2601 · Cited by 231 · see citing works

Changes in Physical Properties of Stored Erthrocytes

Hradin, A. R., Weed, R. I., & Reed, C. F. (1969) · Transfusion · doi:10.1111/j.1537-2995.1969.tb04929.x · Cited by 204 · see citing works

Coupling Heme and Iron Metabolism <i>via</i> Ferritin H Chain

Gozzelino, R., & Soares, M. P. (2014) · Antioxidants &amp; Redox Signaling · doi:10.1089/ars.2013.5666 · Cited by 151 · see citing works

Hemolytic Transfusion Reactions

Strobel, E. (2008) · Transfusion Medicine and Hemotherapy · doi:10.1159/000154811 · Cited by 151 · see citing works

Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility

Larraufie, M., Yang, W. S., Jiang, E., Thomas, A. G., Slusher, B. S., & Stockwell, B. R. (2015) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2015.07.018 · Cited by 135 · see citing works

A novel mouse model of red blood cell storage and posttransfusion in vivo survival

Gilson, C. R., Kraus, T. S., Hod, E. A., Hendrickson, J. E., Spitalnik, S. L., Hillyer, C. D., Shaz, B. H., & Zimring, J. C. (2009) · Transfusion · doi:10.1111/j.1537-2995.2009.02173.x · Cited by 121 · see citing works

Transfusion-related immunomodulation: a reappraisal

Youssef, L. A., & Spitalnik, S. L. (2017) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000376 · Cited by 121 · see citing works

Transfusion of 28‐day‐old leucoreduced or non‐leucoreduced stored red blood cells induces an inflammatory response in healthy dogs

Callan, M. B., Patel, R. T., Rux, A. H., Bandyopadhyay, S., Sireci, A. N., O’Donnell, P. A., Ruane, T., Sikora, T. U., Marryott, K., Sachais, B. S., et al. (2013) · Vox Sanguinis · doi:10.1111/vox.12058 · Cited by 77 · see citing works

Autoimmune hemolytic anemia: From lab to bedside

Chaudhary, R., & Das, S. (2014) · Asian Journal of Transfusion Science · doi:10.4103/0973-6247.126681 · Cited by 72 · see citing works

Transfusion and Pneumonia in the Trauma Intensive Care Unit: An Examination of the Temporal Relationship

Vandromme, M. J., McGwin, G., Marques, M. B., Kerby, J. D., Rue, L. W., & Weinberg, J. A. (2009) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0b013e3181a5a8f9 · Cited by 54 · see citing works

Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells

Meinderts, S. M., Oldenborg, P., Beuger, B. M., Klei, T. R. L., Johansson, J., Kuijpers, T. W., Matozaki, T., Huisman, E. J., de Haas, M., van den Berg, T. K., et al. (2017) · Blood Advances · doi:10.1182/bloodadvances.2017004671 · Cited by 48 · see citing works

Murine malaria: blood clearance and organ sequestration of Plasmodium yoelii-infected erythrocytes

Smith, L., Hunter, K. W., Oldfield, E. C., & Strickland, G. T. (1982) · Infection and Immunity · doi:10.1128/iai.38.1.162-167.1982 · Cited by 28 · see citing works

Macrophages clear refrigerator storage–damaged red blood cells and subsequently secrete cytokines in vivo, but not in vitro, in a murine model

Wójczyk, B. S., Kim, N., Bandyopadhyay, S., Francis, R. O., Zimring, J. C., Hod, E. A., & Spitalnik, S. L. (2014) · Transfusion · doi:10.1111/trf.12755 · Cited by 26 · see citing works

Increased susceptibility to infection in sickle cell disease: defects of opsonization and of splenic function.

Rb, J., Sl, N., & Ag, S. (1975) · PubMed · Cited by 13 · see citing works

Ferroptosis in infection, inflammation, and immunity

Chen, X., Kang, R., Kroemer, G., & Tang, D. (2021) · The Journal of Experimental Medicine · doi:10.1084/jem.20210518 · Cited by 829 · see citing works

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

Feng, H., & Stockwell, B. R. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2006203 · Cited by 759 · see citing works

The application of Ferroptosis in diseases

Qiu, Y., Cao, Y., Cao, W., Jia, Y., & Lu, N. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104919 · Cited by 415 · see citing works

Living on the Edge: Efferocytosis at the Interface of Homeostasis and Pathology

Morioka, S., Maueröder, C., & Ravichandran, K. S. (2019) · Immunity · doi:10.1016/j.immuni.2019.04.018 · Cited by 391 · see citing works

Interaction between macrophages and ferroptosis

Yang, Y., Wang, Y., Guo, L., Gao, W., Tang, T., & Yan, M. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04775-z · Cited by 369 · see citing works

Iron in infection and immunity

Nairz, M., & Weiss, G. (2020) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2020.100864 · Cited by 359 · see citing works

Ironing out the role of ferroptosis in immunity

Bell, H. N., Stockwell, B. R., & Zou, W. (2024) · Immunity · doi:10.1016/j.immuni.2024.03.019 · Cited by 234 · see citing works

Programmed death of macrophages in atherosclerosis: mechanisms and therapeutic targets

Meyer, G. R. Y. D., Zurek, M., Puylaert, P., & Martinet, W. (2024) · Nature Reviews Cardiology · doi:10.1038/s41569-023-00957-0 · Cited by 216 · see citing works

In defence of ferroptosis

Alves, F. M., Lane, D. J. R., Nguyen, T. P. M., Bush, A. I., & Ayton, S. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02088-5 · Cited by 197 · see citing works

Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal

Nishizawa, H., Yamanaka, M., & Igarashi, K. (2022) · FEBS Journal · doi:10.1111/febs.16382 · Cited by 163 · see citing works

Challenges and advances in the management of inflammation in atherosclerosis

Xing, Y., & Lin, X. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.06.016 · Cited by 142 · see citing works

Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis

Liu, W., Östberg, N. K., Yalçınkaya, M., Dou, H., Endo‐Umeda, K., Tang, Y., Hou, X., Xiao, T., Fidler, T. P., Abramowicz, S., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci155724 · Cited by 127 · see citing works

Zinc transporter ZIP7 is a novel determinant of ferroptosis

Chen, P., Wu, J., Xu, Y., Ding, C. C., Mestre, A. A., Lin, C., Yang, W., & Chi, J. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03482-5 · Cited by 128 · see citing works

Emerging roles of ferroptosis in the tumor immune landscape: from danger signals to anti‐tumor immunity

Shi, L., Liu, Y., Li, M., & Luo, Z. Y. (2021) · FEBS Journal · doi:10.1111/febs.16034 · Cited by 127 · see citing works

Ferroptosis: an emerging player in immune cells

Xu, S., Min, J., & Wang, F. (2021) · 中国科学通报：英文版 · doi:10.1016/j.scib.2021.02.026 · Cited by 118 · see citing works

Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport

Nemkov, T. G., Reisz, J. A., Xia, Y., Zimring, J. C., & D’Alessandro, A. (2018) · Expert Review of Proteomics · doi:10.1080/14789450.2018.1531710 · Cited by 113 · see citing works

The Role of Macrophage Iron Overload and Ferroptosis in Atherosclerosis

Ma, J., Zhang, H., Chen, Y., Liu, X., Tian, J., & Shen, W. (2022) · Biomolecules · doi:10.3390/biom12111702 · Cited by 116 · see citing works

Embryonal erythropoiesis and aging exploit ferroptosis

Zheng, H., Jiang, L., Tsuduki, T., Conrad, M., & Toyokuni, S. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102175 · Cited by 107 · see citing works

Dysregulation of iron metabolism in cancer stem cells

Recalcati, S., Gammella, E., & Cairo, G. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.07.015 · Cited by 107 · see citing works

Regulated Necrosis in Atherosclerosis

Puylaert, P., Zurek, M., Rayner, K. J., Meyer, G. R. Y. D., & Martinet, W. (2022) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.122.318177 · Cited by 105 · see citing works

Emerging Mechanisms and Disease Implications of Ferroptosis: Potential Applications of Natural Products

Ge, C., Zhang, S., Mu, H., Shaojun, Z., Tan, Z., Huang, X., Chen, X., Zou, J., Zhu, Y., Dong, F., et al. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.774957 · Cited by 77 · see citing works

Programmed Death of Microglia in Alzheimer's Disease: Autophagy, Ferroptosis, and Pyroptosis

Qiu, Z., Zhang, H., Xia, M., Gu, J., Guo, K., Wang, H., & Miao, C. (2023) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2023.3 · Cited by 76 · see citing works

Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds

Wlaschek, M., Singh, K., Sindrilaru, A., Crisan, D., & Scharffetter-Kochanek, K. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.036 · Cited by 76 · see citing works

Macrophages and Iron: A Special Relationship

Recalcati, S., & Cairo, G. (2021) · Biomedicines · doi:10.3390/biomedicines9111585 · Cited by 74 · see citing works

T lymphocyte-derived extracellular vesicles aggravate abdominal aortic aneurysm by promoting macrophage lipid peroxidation and migration via pyruvate kinase muscle isozyme 2

Dang, G., Li, T., Yang, D., Yang, G., Du, X., Yang, J., Miao, Y., Han, L., Ma, X., Song, Y., et al. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102257 · Cited by 75 · see citing works

Iron Metabolism in the Tumor Microenvironment: Contributions of Innate Immune Cells

Liang, W. P., & Ferrara, N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.626812 · Cited by 74 · see citing works

Escherichia coli induced ferroptosis in red blood cells of grass carp (Ctenopharyngodon idella)

Yang, M., Lu, Z., Li, F., Shi, F., Zhan, F., Zhao, L., Li, Y., Li, J., Lin, L., & Qin, Z. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2020.09.036 · Cited by 71 · see citing works

Redox signaling in innate immunity and inflammation: focus on macrophages and neutrophils

Braunstein, I., Motohashi, H., Dallenga, T. K., Schaible, U. E., & Benhar, M. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.06.006 · Cited by 72 · see citing works

Cytoprotective Role of Heme Oxygenase-1 in Cancer Chemoresistance: Focus on Antioxidant, Antiapoptotic, and Pro-Autophagy Properties

Wang, H., Cheng, Q., Bao, L., Li, M., Chang, K., & Yi, X. (2023) · Antioxidants · doi:10.3390/antiox12061217 · Cited by 67 · see citing works

The Multiple Facets of Iron Recycling

Slusarczyk, P., & Mleczko‐Sanecka, K. (2021) · Genes · doi:10.3390/genes12091364 · Cited by 60 · see citing works

Ferroptosis in tumor immunity and therapy

Gong, C., Ji, Q., Wu, M., Tu, Z., Lei, K., Luo, M., Liu, J., Lin, L., Li, K., Li, J., et al. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17529 · Cited by 56 · see citing works

Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation

Olonisakin, T. F., Suber, T. L., Gonzalez-Ferrer, S., Xiong, Z., Peñaloza, H. F., van der Geest, R., Xiong, Y., Osei-Hwedieh, D. O., Tejero, J., Rosengart, M. R., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci137468 · Cited by 54 · see citing works

Erastin‑induced ferroptosis causes physiological and pathological changes in healthy tissues of mice

Zhao, J., Xu, B., Xiong, Q., Feng, Y., & Du, H. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12352 · Cited by 55 · see citing works

Ferroptosis: A Critical Moderator in the Life Cycle of Immune Cells

Wang, P., & Lu, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.877634 · Cited by 56 · see citing works

Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease

Liu, Y., Pal, M., Bao, W., Shi, P. A., Lobo, C. A., An, X., Manwani, D. G., Zhong, H., & Yazdanbakhsh, K. (2021) · Blood · doi:10.1182/blood.2021011629 · Cited by 53 · see citing works

Link of sorafenib resistance with the tumor microenvironment in hepatocellular carcinoma: Mechanistic insights

Tian, X., Yan, T., Liu, F., Liu, Q., Zhao, J., Xiong, H., & Jiang, S. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.991052 · Cited by 53 · see citing works

The Intersection of DNA Damage Response and Ferroptosis—A Rationale for Combination Therapeutics

Chen, P.-H., Tseng, W. H.-S., & Chi, J. (2020) · Biology · doi:10.3390/biology9080187 · Cited by 51 · see citing works

Modulation of Iron Metabolism in Response to Infection: Twists for All Tastes

Gomes, A. C., Moreira, A. C., Mesquita, G., & Gomes, M. S. (2018) · Pharmaceuticals · doi:10.3390/ph11030084 · Cited by 50 · see citing works

Patrolling monocytes scavenge endothelial-adherent sickle RBCs: a novel mechanism of inhibition of vaso-occlusion in SCD

Liu, Y., Zhong, H., Bao, W., Mendelson, A., An, X., Shi, P. A., Chou, S. T., Manwani, D. G., & Yazdanbakhsh, K. (2019) · Blood · doi:10.1182/blood.2019000172 · Cited by 48 · see citing works

Macrophage‐fibroblast circuits in the spleen

Bellomo, A., Gentek, R., Golub, R., & Bajénoff, M. (2021) · Immunological Reviews · doi:10.1111/imr.12979 · Cited by 44 · see citing works

Effect of erythrophagocytosis-induced ferroptosis during angiogenesis in atherosclerotic plaques

Puylaert, P., Roth, L., Praet, M. V., Pintelon, I., Dumitrascu, C., van Nuijs, A. L. N., Klejborowska, G., Guns, P., Berghe, T. V., Augustyns, K., et al. (2023) · Angiogenesis · doi:10.1007/s10456-023-09877-6 · Cited by 46 · see citing works

Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer

Deng, C., Xiong, L., Chen, Y., Wu, K., & Wu, J. (2023) · BMC Pulmonary Medicine · doi:10.1186/s12890-023-02655-6 · Cited by 46 · see citing works

Impaired iron recycling from erythrocytes is an early hallmark of aging

Slusarczyk, P., Mandal, P. K., Zurawska, G., Niklewicz, M., Chouhan, K., Mahadeva, R., Jończy, A., Macias, M., Szybińska, A., Cybulska, M., et al. (2023) · eLife · doi:10.7554/elife.79196 · Cited by 40 · see citing works

Ferroptosis, novel therapeutics in asthma

Lv, X., Dong, M., Tang, W., Qin, J., Wang, W., Li, M., Teng, F., Yi, L., Dong, J., & Wei, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113516 · Cited by 43 · see citing works

Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics.

Li, Z.-H., Zhang, Y., Ji, M.-L., Wu, C.-L., Zhang, Y.-X., & Ji, S. (2024) · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · doi:10.1016/j.biopha.2024.116777 · Cited by 38 · see citing works

Metabolic Consequences of Efferocytosis and Its Impact on Atherosclerosis

Yurdagul, A. (2021) · Immunometabolism · doi:10.20900/immunometab20210017 · Cited by 40 · see citing works

The role of ROS-induced pyroptosis in CVD

Tian, K.-J., Yu, Y., Zhou, K., Deng, N.-H., Tian, Z., Wu, Z.-F., Liu, X., Zhang, F., & Jiang, Z. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1116509 · Cited by 39 · see citing works

Resident macrophages of the lung and liver: The guardians of our tissues

Kulle, A., Thanabalasuriar, A., Cohen, T. S., & Szydlowska, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1029085 · Cited by 39 · see citing works

The Intrinsic Biological Identities of Iron Oxide Nanoparticles and Their Coatings: Unexplored Territory for Combinatorial Therapies

Mulens‐Arias, V., Rojas, J. M., & Barber, D. F. (2020) · Nanomaterials · doi:10.3390/nano10050837 · Cited by 38 · see citing works

The Chemical Basis of Intracerebral Hemorrhage and Cell Toxicity With Contributions From Eryptosis and Ferroptosis

Derry, P. J., Vo, A. T. T., Gnanasekaran, A., Mitra, J., Liopo, A. V., Hegde, M. L., Tsai, A., Tour, J. M., & Kent, T. A. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.603043 · Cited by 40 · see citing works

Targeting reactive oxygen species and fat acid oxidation for the modulation of tumor-associated macrophages: a narrative review

Teng, Y., Xu, L., Li, W., Liu, P., Tian, L., & Liu, M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1224443 · Cited by 37 · see citing works

Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia

Vallelian, F., Buzzi, R. M., Pfefferlé, M., Yalamanoglu, A., Dubach, I. L., Wassmer, A., Gentinetta, T., Hansen, K., Humar, R., Schulthess, N., et al. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-022-00932-1 · Cited by 33 · see citing works

Red Blood Cell Storage: From Genome to Exposome Towards Personalized Transfusion Medicine

D’Alessandro, A., & Hod, E. A. (2023) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2023.150750 · Cited by 35 · see citing works

Erythrophagocytosis by Microglia/Macrophage in Intracerebral Hemorrhage: From Mechanisms to Translation

Liu, J., Zhu, Z., & Leung, G. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.818602 · Cited by 34 · see citing works

Understanding the mechanistic roles of microplastics combined with heavy metals in regulating ferroptosis: Adding new paradigms regarding the links with diseases

Chen, Q., Liu, Y., Bi, L., Jin, L., & Peng, R. (2023) · Environmental Research · doi:10.1016/j.envres.2023.117732 · Cited by 35 · see citing works

Reticulocytes in donor blood units enhance red blood cell alloimmunization

Thomas, T. A., Qiu, A., Kim, C. Y., Gordy, D. E., Miller, A., Tredicine, M., Dzieciątkowska, M., Zotti, F. D., Hod, E. A., D’Alessandro, A., et al. (2023) · Haematologica · doi:10.3324/haematol.2023.282815 · Cited by 33 · see citing works

The dance of macrophage death: the interplay between the inevitable and the microenvironment

Makuch, M., Stepanechko, M., & Bzowska, M. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1330461 · Cited by 33 · see citing works

Thymosin β4 Is an Endogenous Iron Chelator and Molecular Switcher of Ferroptosis

Lachowicz, J. I., Pichiri, G., Piludu, M., Fais, S., Orrù, G., Congiu, T., Piras, M., Faa, G., Fanni, D., Torre, G. D., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23010551 · Cited by 32 · see citing works

Red Blood Cell Omics and Machine Learning in Transfusion Medicine: Singularity Is Near

D’Alessandro, A. (2023) · Transfusion Medicine and Hemotherapy · doi:10.1159/000529744 · Cited by 31 · see citing works

Immune cells dying from ferroptosis: mechanisms and therapeutic opportunities

Liu, J., Dong, R., Yuan, B., Xie, Y., Feng, Z., Zhou, S., Luan, F., & Chen, Y. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-08204-9 · Cited by 32 · see citing works

Interaction between macrophages and ferroptosis: Metabolism, function, and diseases

Jiang, Q., Wan, R., Jiang, J., Li, T., Li, Y., Yu, S., Zhao, B., & Li, Y. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003189 · Cited by 30 · see citing works

Transcriptomic reveals the ferroptosis features of host response in a mouse model of Zika virus infection

Yan, Q., Zheng, W., Jiang, Y., Zhou, P., Lai, Y., Liu, C., Wu, P., Zhuang, H., Huang, H.-T., Li, G., et al. (2022) · Journal of Medical Virology · doi:10.1002/jmv.28386 · Cited by 30 · see citing works

The crosslinks between ferroptosis and autophagy in asthma

Lv, X., Tang, W., Qin, J., Wang, W., Dong, J., & Wei, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1140791 · Cited by 30 · see citing works

Too much iron: A masked foe for leukemias

Brissot, É., Bernard, D. G., Loréal, O., Brissot, P., & Troadec, M. (2019) · Blood Reviews · doi:10.1016/j.blre.2019.100617 · Cited by 28 · see citing works

Emerging insights into the role of ferroptosis in the pathogenesis of autoimmune diseases

Fan, J., Jiang, T., & He, D. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1120519 · Cited by 27 · see citing works

Metabolic Reprogramming of Mouse Bone Marrow Derived Macrophages Following Erythrophagocytosis

Catala, A., Youssef, L. A., Reisz, J. A., Dzieciątkowska, M., Powers, N. E., Marchetti, C., Karafin, M. S., Zimring, J. C., Hudson, K. E., Hansen, K. C., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00396 · Cited by 26 · see citing works

Ferroptosis: a potential target for the treatment of atherosclerosis

Li, C., Liu, R., Xiong, Z., Bao, X., Liang, S., Zeng, H., Wei, J. J., Gong, Q., Liu, L., & Guo, J. (2024) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2024016 · Cited by 25 · see citing works

A double-edged sword with a therapeutic target: iron and ferroptosis in immune regulation

Ni, S., Yuan, Y., Song, S., & Li, X. (2022) · Nutrition Reviews · doi:10.1093/nutrit/nuac071 · Cited by 24 · see citing works

Ferroptosis as an emerging target in sickle cell disease

Fortuna, V., Lima, J. C., Oliveira, G. F., de Oliveira, Y. S. C., Getachew, B., Nekhai, S. A., Aschner, M., & Tizabi, Y. (2024) · Current Research in Toxicology · doi:10.1016/j.crtox.2024.100181 · Cited by 25 · see citing works

The emerging role of ferroptosis in the pathological development and progression of sepsis

Zhou, H., Huang, J., Liu, Y., Wang, J., & Wang, J. (2025) · Military Medical Research · doi:10.1186/s40779-025-00665-5 · Cited by 29 · see citing works

Ferroptosis in periodontitis: mechanisms, impacts, and systemic connections

Guan, P., Ruan, Q., Li, J., Xi, M., Qi, W., Ko, K. I., & Ni, J. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02550-5 · Cited by 25 · see citing works

Ferroptosis of epithelial ovarian cancer: genetic determinants and therapeutic potential

Lin, C., & Chi, J. (2020) · Oncotarget · doi:10.18632/oncotarget.27749 · Cited by 22 · see citing works

HIF-1α/m6A/NF-κB/CCL3 axis-mediated immunosurveillance participates in low level benzene-related erythrohematopoietic development toxicity

Cong, X., Li, X., Xu, K., Yin, L., Liang, G., Sun, R., Pu, Y., & Zhang, J. (2024) · Environment International · doi:10.1016/j.envint.2024.108493 · Cited by 22 · see citing works

The m6A eraser FTO suppresses ferroptosis via mediating ACSL4 in LPS-induced macrophage inflammation

Zhao, Y., Ding, W., Cai, Y., Li, Q., Zhang, W., Bai, Y., Zhang, Y., Xu, Q., & Feng, Z. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167354 · Cited by 21 · see citing works

Myeloperoxidase as a Marker to Differentiate Mouse Monocyte/Macrophage Subsets

Gurski, C. J., & Dittel, B. N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158246 · Cited by 22 · see citing works

Inductively-Coupled Plasma Mass Spectrometry–Novel Insights From an Old Technology Into Stressed Red Blood Cell Physiology

Stephenson, D., Nemkov, T. G., Qadri, S. M., Sheffield, W. P., & D’Alessandro, A. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.828087 · Cited by 19 · see citing works

Crosstalk between ferroptosis and innate immune in diabetic kidney disease: mechanisms and therapeutic implications

Wang, J., Shi, H., Yang, Y. S., & Gong, X. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1505794 · Cited by 21 · see citing works

Novel concepts in red blood cell clearance

Neri, S., Swinkels, D. W., Matlung, H. L., & van Bruggen, R. (2021) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000679 · Cited by 18 · see citing works

Innate Lymphoid Cells and Adaptive Immune Cells Cross-Talk: A Secret Talk Revealed in Immune Homeostasis and Different Inflammatory Conditions

Kumar, V. (2021) · International Reviews of Immunology · doi:10.1080/08830185.2021.1895145 · Cited by 18 · see citing works

A new role for erythropoietin in the homeostasis of red blood cells

Arias, C. F., Valente-Leal, N., Bertocchini, F., Marques, S., Acosta, F. J., & Fernández-Arias, C. (2024) · Communications Biology · doi:10.1038/s42003-023-05758-2 · Cited by 18 · see citing works

Is ferroptosis immunogenic? The devil is in the details!

Kepp, O., & Kroemer, G. (2022) · OncoImmunology · doi:10.1080/2162402x.2022.2127273 · Cited by 17 · see citing works

Nrf2 sensitizes ferroptosis through L-2-hydroxyglutarate-mediated chromatin modifications in sickle cell disease

Xi, C., Pang, J., Zhi, W., Chang, C., Siddaramappa, U., Shi, H., Horuzsko, A., Pace, B. S., & Zhu, X. (2023) · Blood · doi:10.1182/blood.2022018159 · Cited by 16 · see citing works

When might transferrin, hemopexin or haptoglobin administration be of benefit following the transfusion of red blood cells?

Buehler, P. W., & Karnaukhova, E. (2018) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000458 · Cited by 16 · see citing works

TLR7 modulates extramedullary splenic erythropoiesis in P. yoelii NSM-infected mice through the regulation of iron metabolism of macrophages with IFN-γ

Li, J., Liu, L., Xing, J., Chen, D., Fang, C., Mo, F., Gong, Y., Tan, Z., Liang, G., Xiao, W. L., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1123074 · Cited by 15 · see citing works

Post-Transfusion Hemophagocytosis Without Hemophagocytic Lymphohistiocytosis

McGinnis, E., Medvedev, N., Richards, M. J., Chen, L. Y. C., & Wong, M. P. (2019) · Mayo Clinic Proceedings Innovations Quality & Outcomes · doi:10.1016/j.mayocpiqo.2019.07.001 · Cited by 15 · see citing works

Ferroptosis in Oral Cancer: Mechanistic Insights and Clinical Prospects

Lee, J., & Roh, J. (2025) · Cells · doi:10.3390/cells14211685 · Cited by 14 · see citing works

Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation

Schaefer, R. E. M., Callahan, R. C., Atif, S. M., Orlicky, D. J., Cartwright, I. M., Fontenot, A. P., Colgan, S. P., & Onyiah, J. C. (2021) · Mucosal Immunology · doi:10.1038/s41385-021-00474-8 · Cited by 14 · see citing works

Polysaccharide of Atractylodes macrocephala Koidz Alleviates Cyclophosphamide-Induced Thymus Ferroptosis in Gosling

Zhou, X., Cao, N., Xu, D., Tian, Y., Shen, X., Jiang, D., Huang, Y., Li, W., & Li, B. (2022) · Animals · doi:10.3390/ani12233394 · Cited by 14 · see citing works

Ferroptosis of Endothelial Cells Triggered by Erythrophagocytosis Contributes to Thrombogenesis in Uremia

Li, Z., Yan, M., Wang, Z., An, Y., Wei, X., Li, T., Xu, M., Xia, Y., Wang, L., & Gao, C. (2023) · Thrombosis and Haemostasis · doi:10.1055/a-2117-7890 · Cited by 14 · see citing works

Reprogramming of red blood cell metabolism in Zika virus–infected donors

Catala, A., Stone, M., Busch, M. P., & D’Alessandro, A. (2022) · Transfusion · doi:10.1111/trf.16851 · Cited by 14 · see citing works

IL-18 Binding Protein–Producing Cells Attenuate Anemia in Murine Macrophage Activation Syndrome

Harel, M., Fauteux‐Daniel, S., Rodriguez, E., Palmer, G., & Gabay, C. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2300065 · Cited by 12 · see citing works

Autoantibody-Mediated Erythrophagocytosis Increases Tuberculosis Susceptibility in HIV Patients

Dai, Y., Cai, Y., Wang, X., Zhu, J., Liu, X., Liu, H., Li, L., Zhang, Y., Liu, S., Wen, Z., et al. (2020) · mBio · doi:10.1128/mbio.03246-19 · Cited by 13 · see citing works

Metronomic capecitabine with rapamycin exerts an immunosuppressive effect by inducing ferroptosis of CD4+ T cells after liver transplantation in rat

Wang, H., Yang, R., Wang, Z.-L., Cao, L., Kong, D., Sun, Q., Yoshida, S., Ren, J., Chen, T., Duan, J., et al. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110810 · Cited by 12 · see citing works

Ferroptosis contributes to immunosuppression

He, N., Yuan, D., Luo, M., Xu, Q., Wen, Z., Wang, Z., Zhao, J., & Liu, Y. (2024) · Frontiers of Medicine · doi:10.1007/s11684-024-1080-8 · Cited by 13 · see citing works

Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy

Vøls, K. K., Kjelgaard-Hansen, M. J., Ley, C. D., Hansen, A. K., & Petersen, M. (2019) · Haemophilia · doi:10.1111/hae.13672 · Cited by 12 · see citing works

Identification of hub genes and pathways of ferroptosis in Fusarium keratitis by bioinformatics methods

Teng, X., Xiong, X., Sha, X.-Y., Lei, Y., Diao, Y., Liu, J., Tian, Y., Liu, L., & Zhong, J. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1103471 · Cited by 12 · see citing works

Blocking the CD47-SIRPα interaction reverses the disease phenotype in a polycythemia vera mouse model

Lysenko, V., Schürch, P. M., Tuzlak, S., van Wijk, N. W.-V., Kovtonyuk, L. V., Becher, B., Manz, M. G., Kreutmair, S., & Theocharides, A. P. A. (2023) · Leukemia · doi:10.1038/s41375-023-01903-2 · Cited by 12 · see citing works

Disrupting the immune homeostasis: the emerging role of macrophage ferroptosis in autoimmune diseases

Liu, T., Huang, Y., Wang, Y., & Shen, H. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114745 · Cited by 12 · see citing works

Macrophage ferroptosis potentiates GCN2 deficiency induced pulmonary venous arterialization

Zhang, J., Mao, P., Zhou, T., Yue, B., Li, Y., Qiu, Y., Ying, K., Wang, F., Chen, J., & Yang, J. H. (2025) · Nature Communications · doi:10.1038/s41467-025-64035-4 · Cited by 11 · see citing works

Synthesis and Optimization of Nitroxide-Based Inhibitors of Ferroptotic Cell Death in Cancer Cells and Macrophages

Charaschanya, M., Maskrey, T. S., LaPorte, M. G., Janjic, J. M., & Wipf, P. (2022) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.1c00561 · Cited by 11 · see citing works

Increased erythrophagocytosis induces ferroptosis in macrophages and alters the immune response to subsequent stimuli

Youssef, L. A. (2018) · doi:10.7916/d8tb2qxg

Erythrocyte deformability has no influence on the rate of erythrophagocytosis in vitro by autologous human monocytes/macrophages

(1995) · Transfusion Medicine Reviews · doi:10.1016/s0887-7963(05)80044-6 · Cited by 1 · see citing works

S904 THE FUNCTIONAL RESPONSE OF IRON‐RECYCLING AND INFECTION CONTROL‐SPECIALIZED MACROPHAGES IS IMPAIRED BY TRANSFUSIONS AND AMELIORATED BY IRON CHELATION

Passos, S. F., Sparla, R., Rauner, M., Weidner, H., Yazdanbakhsh, K., Platzbecker, U., Muckenthaler, M. U., & Vinchi, F. (2019) · HemaSphere · doi:10.1097/01.hs9.0000561896.88433.31

CD71 + Red Blood Cells Mediate Increased Erythrophagocytosis and Reduce Monocyte Number in a Monocyte Suspension Assay

Li, W., & Acker, J. P. (2026) · Scandinavian Journal of Immunology · doi:10.1111/sji.70087 · Cited by 1 · see citing works

The Role of Nramp1 in Erythrophagocytosis.

Soe-Lin, S., Sheftel, A. D., & Ponka, P. (2007) · Blood · doi:10.1182/blood.v110.11.3851.3851