Consumption of low-fat dairy foods for 6 months improves insulin resistance without adversely affecting lipids or bodyweight in healthy adults: a randomized free-living cross-over study
Open accessAbstract
BACKGROUND: Given the highly debated role of dairy food consumption in modulating biomarkers of metabolic syndrome, this study was conducted to examine the influence of long-term (6 month) dairy consumption on metabolic parameters in healthy volunteers under free-living conditions without energy restriction. METHODS: Twenty-three healthy subjects completed a randomized, crossover trial of 12 months. Participants consumed their habitual diets and were randomly assigned to one of two treatment groups: a high dairy supplemented group instructed to consume 4 servings of dairy per day (HD); or a low dairy supplemented group limited to no more than 2 servings of dairy per day (LD). Baseline, midpoint, and endpoint metabolic responses were examined. RESULTS: Endpoint measurements of body weight and composition, energy expenditure, blood pressure, blood glucose, and blood lipid and lipoprotein responses did not differ (p > 0.05) between the LD and HD groups. HD consumption improved (p < 0.05) plasma insulin (-9%) and insulin resistance (-11%, p = 0.03) as estimated by HOMA-IR compared with the LD group. CONCLUSIONS: Study results suggest that high dairy consumption (4 servings/d) may improve insulin resistance without negatively impacting bodyweight or lipid status under free-living conditions. TRIAL REGISTRATION: Clinical Trials.gov: NCT01761955.
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Increased low-fat dairy consumption is associated with lower LDL-C, triglycerides, plasma insulin, insulin resistance, waist circumference, BMI, possibly BP, and reduced diabetes risk.
“However, increased low-fat dairy consumption is associated with lower LDL-C, triglycerides, plasma insulin, insulin resistance, waist circumference, BMI, possibly blood pressure (BP); and reduced diabetes risk (174–182).”
From Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System (2015) · cites this paper as [178]
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- Authors
- Rideout, T. C., Marinangeli, C. P. F., Martin, H., Browne, R. W., & Rempel, C. B.
- Affiliations
- University at Buffalo, State University of New York (US)
- University of Manitoba (CA)
- Corresponding author
- Rideout, Todd C
- Rempel, Curtis B
- Venue
- Nutrition Journal
- Published
- 2013-05-02
- Volume
- 12
- Issue
- 1
- Pages
- 56-56
- ISSN
- 1475-2891 (ISSN-L)
- PMC
- PMC3651862
- OpenAlex
- W2106944445
- Cited by
- 89
- References
- 55
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 4 · 2022: 2 · 2021: 5 · 2020: 8 · 2019: 15 · 2018: 6 · 2017: 10 · 2016: 11 · 2015: 7 · 2014: 10 · 2013: 8
- FWCI
- 12.24
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrition Journal (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Mspace (University of Manitoba) (submittedVersion)
- Funders
- University at Buffalo
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Keywords
- dairy consumption, insulin resistance, metabolic syndrome, plasma insulin, HOMA-IR, serum lipids, lipoproteins, body weight, body composition, energy expenditure, blood pressure, blood glucose, healthy adults, free-living conditions
- MeSH terms
- Adult, Aged, Blood Glucose, Blood Pressure, Body Composition, Body Weight, Dairy Products, Diet, Energy Metabolism, Female, Humans, Insulin, Insulin Resistance, Lipids, Male, Middle Aged, Body Mass Index, Cross-Over Studies, Endpoint Determination, Young Adult
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