Psychological treatments for common mental health problems experienced by informal carers of adults with chronic physical health conditions (protocol)
Open accessAbstract
BACKGROUND: Improved life expectancy is resulting in increased outpatient treatment of people with chronic physical health conditions and reliance on the provision of informal care in the community. However, informal care is also associated with increased risk of experiencing common mental health difficulties such as depression and anxiety. Currently there is a lack of evidence-based treatments for such difficulties, resulting in poor health outcomes for both the informal carer and care recipient. METHODS/DESIGN: Electronic databases will be systemically searched for randomised controlled trials examining the effectiveness of psychological interventions targeted at treating depression or anxiety experienced by informal carers of patients with chronic physical health conditions. Database searches will be supplemented by contact with experts, reference and citation checking and grey literature. Both published and unpublished research in English language will be reviewed with no limitations on year or source. Individual, group and patient-carer dyad focused interventions will be eligible. Primary outcomes of interest will be validated self-report or clinician administered measures of depression or anxiety. If data allows a meta-analysis will examine: (1) the overall effectiveness of psychological interventions in relation to outcomes of depression or anxiety; (2) intervention components associated with effectiveness. DISCUSSION: This review will provide evidence on the effectiveness of psychological interventions for depression and anxiety experienced by informal carers of patients with chronic physical health conditions. In addition, it will examine intervention components associated with effectiveness. Results will inform the design and development of a psychological intervention for carers of people with chronic physical health conditions experiencing depression and anxiety. PROSPERO registration number: CRD42012003114.
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Excluding high risk of bias RCTs is a technique used in previous systematic reviews and meta-analyses.
“and is a technique used in previous systematic reviews and meta-analyses.80–82”
From Effectiveness and acceptability of cognitive-behavioural therapy based interventions for maternal peripartum depression: A systematic review, meta-analysis and thematic synthesis protocol (2019) · cites this paper as [82]
The Methods > Inclusion and exclusion criteria passage says the planned review will include only RCTs assessed as having low or unclear risk of bias for random sequence generation and allocation concealment. This supports excluding trials at high risk on those criteria, but the paper is a protocol: it does not show that a completed systematic review or meta-analysis used the technique. (LLM, conf=0.85)
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Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · see citing works
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · see citing works
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859 · see citing works
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763 · see citing works
Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575 · see citing works
Duval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099 · see citing works
Developing and evaluating complex interventions: the new Medical Research Council guidance
Craig, P., Dieppe, P., Macintyre, S., Michie, S., Nazareth, I., & Petticrew, M. (2008) · BMJ · doi:10.1136/bmj.a1655 · Cited by 10,995 · see citing works
Cane, J., O’Connor, D., & Michie, S. (2012) · Implementation Science · doi:10.1186/1748-5908-7-37 · Cited by 4,888 · cited 1× · see citing works
“Additionally, when such components have been identified through approaches such as systematic reviews, it has been reported that too little attention has then been paid to identifying the specific components associated with effectiveness [29,30].”
BackgroundAgeing populations: the challenges ahead
Christensen, K., Doblhammer, G., Rau, R., & Vaupel, J. W. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61460-4 · Cited by 3,764 · see citing works
Framework for design and evaluation of complex interventions to improve health
Campbell, M. (2000) · BMJ · doi:10.1136/bmj.321.7262.694 · Cited by 3,474 · see citing works
Assessing Risk of Bias in Included Studies
Higgins, J. P., & Altman, D. G. (2008) · Cochrane Handbook for Systematic Reviews of Interventions · doi:10.1002/9780470712184.ch8 · Cited by 3,396 · see citing works
Systematic reviews: CRD's guidance for undertaking reviews in health care
Tacconelli, E. (2010) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70065-7 · Cited by 3,237 · see citing works
Pinquart, M., & Sörensen, S. (2003) · Psychology and Aging · doi:10.1037/0882-7974.18.2.250 · Cited by 2,857 · see citing works
Publication and related bias in meta-analysis
Sterne, J. A. C., Gavaghan, D., & Egger, M. (2000) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00242-0 · Cited by 2,282 · see citing works
Michie, S., Johnston, M., Francis, J., Hardeman, W., & Eccles, M. (2008) · Applied Psychology · doi:10.1111/j.1464-0597.2008.00341.x · Cited by 1,789 · see citing works
Evaluating patient-based outcome measures for use in clinical trials.
Fitzpatrick, Davey, Buxton, & Jones (1998) · Health Technology Assessment · doi:10.3310/hta2140 · Cited by 1,715 · see citing works
The IMAGE Study Group, Greaves, C. J., Sheppard, K. E., Abraham, C., Hardeman, W., Roden, M., Evans, P. H., & Schwarz, P. (2011) · BMC Public Health · doi:10.1186/1471-2458-11-119 · Cited by 1,163 · see citing works
Kirkham, J. J., Dwan, K. M., Altman, D. G., Gamble, C., Dodd, S., Smyth, R., & Williamson, P. R. (2010) · BMJ · doi:10.1136/bmj.c365 · Cited by 1,133 · see citing works
How Effective Are Interventions With Caregivers? An Updated Meta-Analysis
Sörensen, S., Pinquart, M., & Duberstein, P. R. (2002) · The Gerontologist · doi:10.1093/geront/42.3.356 · Cited by 1,129 · see citing works
Pinquart, M., & Sörensen, S. (2003) · The Journals of Gerontology: Series B · doi:10.1093/geronb/58.2.p112 · Cited by 1,108 · cited 1× · see citing works
“Such difficulties may include the management of behavioural problems [7], physical impairments [20], cognitive decline [21] and the development of communication techniques [22].”
BackgroundMeta‐Analysis of Psychosocial Interventions for Caregivers of People with Dementia
Brodaty, H., Green, A., & Koschera, A. (2003) · Journal of the American Geriatrics Society · doi:10.1034/j.1600-0579.2003.00210.x · Cited by 952 · see citing works
Pinquart, M., & Sorensen, S. (2006) · International Psychogeriatrics · doi:10.1017/s1041610206003462 · Cited by 827 · see citing works
Evaluating patient-based outcome measures for use in clinical trials.
Fitzpatrick, R., Davey, C., Buxton, M. J., et al. (1998) · PubMed · Cited by 781 · see citing works
Informal care and health care use of older adults
Houtven, C. H. V., & Norton, E. C. (2004) · Journal of Health Economics · doi:10.1016/j.jhealeco.2004.04.008 · Cited by 676 · see citing works
Health, life expectancy, and health care spending among the elderly
Lubitz, J., Cai, L., Kramarow, E., & Lentzner, H. (2003) · New England Journal of Medicine · doi:10.1056/nejmsa020614 · Cited by 513 · see citing works
Hesser, H., Weise, C., Westin, V. Z., & Andersson, G. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.12.006 · Cited by 340 · cited 1× · see citing works
“Consistent with other meta-analyses [51,52] subgroup analyses will be considered statistically significant if a P value of ≤0.”
Caring for Mom and Neglecting Yourself? The Health Effects of Caring for an Elderly Parent
Coe, N. B., & Houtven, C. H. V. (2008) · Health Economics · doi:10.1002/hec.1512 · Cited by 311 · see citing works
Emerging models for mobilizing family support for chronic disease management: a structured review
Rosland, A.-M. M., & Piette, J. D. (2010) · Chronic Illness · doi:10.1177/1742395309352254 · Cited by 207 · see citing works
Cannuscio, C. C., Jones, C., Kawachi, I., Colditz, G. A., Berkman, L., & Rimm, E. (2002) · American Journal of Public Health · doi:10.2105/ajph.92.8.1305 · Cited by 171 · see citing works
Longitudinal analysis of multiple indicators of health decline among spousal caregivers
Shaw, W. S., Patterson, T. L., Semple, S. J., Ho, S., Irwin, M. R., Hauger, R. L., & Grant, I. (1997) · Annals of Behavioral Medicine · doi:10.1007/bf02883326 · Cited by 167 · see citing works
Cognitive reframing for carers of people with dementia
Vernooij-Dassen, M., Draskovic, I., McCleery, J., & Downs, M. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005318.pub2 · Cited by 134 · see citing works
Farrand, P., & Woodford, J. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.11.001 · Cited by 125 · see citing works
Non-pharmacological interventions for caregivers of stroke survivors
Legg, L. A., Quinn, T. J., Mahmood, F., Weir, C. J., Tierney, J. F., Stott, D. J., Smith, L. N., & Langhorne, P. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008179.pub2 · Cited by 102 · see citing works
Hopkinson, J. B., Brown, J. C., Okamoto, I., & Addington-Hall, J. M. (2012) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2011.03.013 · Cited by 96 · see citing works
Van Mierlo, L. D., Meiland, F. J. M., Van der Roest, H. G., & Dröes, R. (2012) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2694 · Cited by 94 · cited 1× · see citing works
“patient carer groups such as stroke [25], cancer [26] and dementia [23,27].”
BackgroundSpecifying Evidence-Based Behavior Change Techniques to Aid Smoking Cessation in Pregnancy
Lorencatto, F., West, R., & Michie, S. (2012) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntr324 · Cited by 85 · see citing works
Murray, J., Young, J. B., Förster, A., & Ashworth, R. D. (2003) · Europe PMC (PubMed Central) · Cited by 81 · see citing works
Changes in Adult Child Caregiver Networks
Szinovacz, M. E., & Davey, A. (2007) · The Gerontologist · doi:10.1093/geront/47.3.280 · Cited by 65 · see citing works
A Bound for Publication Bias Based on the Fraction of Unpublished Studies
Copas, J. B., & Jackson, D. (2004) · Biometrics · doi:10.1111/j.0006-341x.2004.00161.x · Cited by 64 · see citing works
Assessing the potential for outcome reporting bias in a review: a tutorial
Dwan, K. M., Gamble, C. L., Kolamunnage‐Dona, R., Mohammed, S., Powell, C., & Williamson, P. R. (2010) · Trials · doi:10.1186/1745-6215-11-52 · Cited by 64 · see citing works
Symptoms of depression in non‐routine caregivers: The role of caregiver strain and burden
Phillips, A. C., Gallagher, S. M., Hunt, K., Der, G., & Carroll, D. (2009) · British Journal of Clinical Psychology · doi:10.1348/014466508x397142 · Cited by 53 · see citing works
Simon, C., Kumar, S., & Kendrick, T. (2009) · Social Science & Medicine · doi:10.1016/j.socscimed.2009.04.007 · Cited by 49 · see citing works
Routine Assistance to Parents: Effects on Daily Mood and Other Stressors
Savla, J. T., Almeida, D. M., Davey, A., & Zarit, S. H. (2008) · The Journals of Gerontology Series B · doi:10.1093/geronb/63.3.s154 · Cited by 48 · see citing works
Perrin, P. B., Heesacker, M., Stidham, B. S., Rittman, M., & Gonzalez‐Rothi, L. J. (2008) · Rehabilitation Psychology · doi:10.1037/0090-5550.53.1.54 · Cited by 44 · see citing works
Formal support of stroke survivors and their informal carers in the community: a cohort study
Simon, C., Kumar, S., & Kendrick, T. (2008) · Health & Social Care in the Community · doi:10.1111/j.1365-2524.2008.00782.x · Cited by 40 · see citing works
Nonpharmacological Interventions for Caregivers of Stroke Survivors
Legg, L. A., Quinn, T. J., Mahmood, F., Weir, C. J., Tierney, J. F., Stott, D. J., Smith, L. N., & Langhorne, P. (2012) · Stroke · doi:10.1161/strokeaha.111.644914 · Cited by 35 · see citing works
Singleton, N. (2002) · Cited by 35 · see citing works
Unpaid carers' access to and use of primary care services
Arksey, H., & Hirst, M. A. (2005) · Primary Health Care Research & Development · doi:10.1191/1463423605pc230oa · Cited by 33 · see citing works
Caregiving for advanced chronic illness patients
Wilkinson, A., & Lynn, J. (2005) · Techniques in Regional Anesthesia and Pain Management · doi:10.1053/j.trap.2005.06.004 · Cited by 30 · see citing works
Application and investigation of a bound for outcome reporting bias
Williamson, P. R., & Gamble, C. (2007) · Trials · doi:10.1186/1745-6215-8-9 · Cited by 26 · see citing works
Strain and satisfaction in caregivers of veterans with chronic illness
Wakefield, B. J., Hayes, J., Boren, S. A., Pak, Y., & Davis, J. W. (2011) · Research in Nursing & Health · doi:10.1002/nur.21456 · Cited by 24 · see citing works
Family carers 4: designing services to support family carers in Sweden
Lundh, U. (1999) · British Journal of Nursing · doi:10.12968/bjon.1999.8.12.6571 · Cited by 11 · see citing works
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Pettman, D., O'Mahen, H., Skoog Svanberg, A., von Essen, L., Axfors, C., Blomberg, O., & Woodford, J. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-032659 · Cited by 24 · see citing works
Rosell‐Murphy, M., Bonet, J. M., Baena, E., Prieto, G., Serrano, E. B., Solé, F. G., Rubio, M., Krier, I., Torres, P., & Mimoso, S. (2014) · BMC Family Practice · doi:10.1186/1471-2296-15-53 · Cited by 32 · see citing works
Mårtensson, E., Blomberg, O., Pettman, D., Sörensdotter, R., von Essén, L., & Woodford, J. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-036402 · Cited by 22 · see citing works
dos Santos, E. R., Michalski, F., & Norris, D. (2021) · Tropical Conservation Science · doi:10.1177/19400829211045788 · Cited by 17 · see citing works
Farrand, P. A., Matthews, J., Dickens, C. M., Anderson, M. P., & Woodford, J. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-009713 · Cited by 15 · see citing works
Coumoundouros, C., von Essén, L., Sanderman, R., & Woodford, J. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-035406 · Cited by 10 · see citing works
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- Authors
- Woodford, J., Farrand, P., Richards, D., & Llewellyn, D. J.
- Affiliations
- University of Exeter (GB)
- Corresponding author
- Woodford, Joanne
- Venue
- Systematic Reviews
- Published
- 2013-01-31
- Volume
- 2
- Issue
- 1
- Pages
- 9-9
- ISSN
- 2046-4053 (ISSN-L)
- PMC
- PMC3599247
- OpenAlex
- W2167257526
- Cited by
- 7
- References
- 55
- Citations by year
- 2021: 1 · 2020: 2 · 2019: 1 · 2016: 1 · 2014: 1 · 2013: 1
- FWCI
- 0.24
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Systematic Reviews (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Uppsala University Publications (Uppsala University) (submittedVersion, other-oa)
- Figshare (submittedVersion)
- Open Research Exeter (University of Exeter) (submittedVersion, cc-by)
- Funders
- National Institute for Health and Care Research (NF-SI-0611-10203)
- Dunhill Medical Trust
- Association of Medical Research Charities
- Topics
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- informal caregivers, chronic physical illness, depression, anxiety, psychological intervention, caregiver mental health, dyadic intervention, intervention components
- MeSH terms
- Anxiety, Chronic Disease, Depression, Humans, Mental Health, Research Design, Treatment Outcome, Caregivers
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