The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Neuroinflammation and fractalkine signaling in Alzheimer’s disease
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In the normal central nervous system, CX3CL1 and its receptor CX3CR1 form a signaling network between neurons and microglia.
“In the normal CNS, CX3CL1 and its receptor CX3CR1 form signaling network between neurons and microglia [25, 26].”
From CX3CL1/CX3CR1 axis attenuates early brain injury via promoting the delivery of exosomal microRNA-124 from neuron to microglia after subarachnoid hemorrhage (2020) · cites this paper as [26]
The CX3CL1/CX3CR1 axis plays an important role in regulating microglial activation and neuroinflammation.
“many studies have confirmed that the CX3CL1/CX3CR1 axis plays an important role in regulating microglial activation and neuroinflammation [26, 27].”
From CX3CL1/CX3CR1 axis attenuates early brain injury via promoting the delivery of exosomal microRNA-124 from neuron to microglia after subarachnoid hemorrhage (2020) · cites this paper as [26]
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Cites
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Absence of CX3CR1 impairs the internalization of Tau by microglia
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“However, 30 days after injury Cx3cr1−/− mice have significantly greater memory impairment on the Morris water maze as well as significantly elevated pro-inflammatory markers compared to wild-type controls [66].”
BackgroundFractalkine overexpression suppresses tau pathology in a mouse model of tauopathy
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“However, the downstream effects of attenuated CX3CR1 on the microglial phenotype and subsequent mechanisms that impact neurodegenerative pathology in AD remain elusive, in part due to the lack of comprehensive, transgenic animal models [14, 39].”
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Metadata
- Authors
- Finneran, D. J., & Nash, K. R.
- ORCID
- Nash, Kevin R.
- Venue
- Journal of Neuroinflammation
- Published
- 2019-02-11
- Volume
- 16
- Issue
- 1
- ISSN
- 1742-2094
- PMC
- PMC6371521
- Cited by
- 132
- References
- 31
- Language
- en
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