Cited by 245Schizophrenia research and treatmentMental Health Treatment and AccessMental Health and Psychiatry

Self-reported psychotic symptoms in the general population: Results from the longitudinal study of the British National Psychiatric Morbidity Survey

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Wiles, Nicola J., Zammit, Stanley, Bebbington, Paul, Singleton, Nicola, Meltzer, Howard, Lewis, Glyn·2006·British Journal of Psychiatry

Abstract

BACKGROUND: Scarce longitudinal data exist on the occurrence of psychotic symptoms in the general population. AIMS: To estimate the incidence of, and risk factors for, self-reported psychotic symptoms in Great Britain. METHOD: Data from the 18-month follow-up of a national survey were used. Incident cases were those who endorsed one or more items on the Psychosis Screening Questionnaire at follow-up, but not at baseline. The association between factors recorded at baseline and incident self-reported symptoms was examined. RESULTS: At follow-up, 4.4% of the general population reported incident psychotic symptoms. Six factors were independently associated with incident symptoms: living in a rural area; having a small primary support group; more adverse life events; smoking tobacco; neurotic symptoms; and engaging in a harmful pattern of drinking. CONCLUSIONS: A small but not insignificant percentage of the population of Great Britain reported incident psychotic symptoms over 18 months. The risk factors for psychotic symptoms showed some similarities with risk factors for schizophrenia, but there were also some striking differences. The relationship between such risk factors and the factors that perpetuate psychotic symptoms remains to be ascertained.

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  • In the NPMS, the association between cannabis dependence and incident psychotic symptoms attenuated and CIs crossed the null after adjustment for confounders.

    “In the NPMS (21) there was an association between cannabis dependence and incident psychotic symptoms 18 months later in the unadjusted analysis, but this attenuated and CIs crossed the null after adjustment for confounders.”
  • In the NPMS, there was an association between cannabis dependence and incident psychotic symptoms 18 months later in the unadjusted analysis.

    “In the NPMS (21) there was an association between cannabis dependence and incident psychotic symptoms 18 months later in the unadjusted analysis, but this attenuated and CIs crossed the null after adjustment for confounders.”

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Authors
Wiles, N. J., Zammit, S., Bebbington, P., Singleton, N., Meltzer, H., & Lewis, G.
Affiliations
  • University of Bristol (GB)
  • Cardiff University (GB)
  • The Royal Free Hospital (GB)
  • Home Office (GB)
  • Office for National Statistics (GB)
Corresponding author
Wiles, Nicola J.
Venue
British Journal of Psychiatry
Published
2006-06
Volume
188
Issue
6
Pages
519-526
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
OpenAlex
W2120843048
Cited by
245
References
39
Citations by year
2026: 2 · 2025: 2 · 2024: 4 · 2023: 10 · 2022: 9 · 2021: 10 · 2020: 12 · 2019: 5 · 2018: 10 · 2017: 13 · 2016: 13 · 2015: 16 · 2014: 15 · 2013: 13 · 2012: 22
FWCI
8.65
Type
journal article
Language
en
Open access
Locations
  • The British Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
  • Bristol Research (University of Bristol) (submittedVersion)
  • Explore Bristol Research (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords
psychotic symptoms, incidence, risk factors, general population, rural residence, social support, life events, smoking, neurotic symptoms, hazardous drinking, schizophrenia risk factors
MeSH terms
Adolescent, Adult, Aged, Epidemiologic Methods, Female, United Kingdom, Humans, Life Change Events, Male, Middle Aged, Psychiatric Status Rating Scales, Psychotic Disorders, Rural Health, Self Disclosure, Smoking, Social Support, Socioeconomic Factors, Alcohol-Related Disorders

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