Cited by 468Schizophrenia research and treatmentCounseling, Therapy, and Family DynamicsPsychiatric care and mental health services

Early intervention services, cognitive–behavioural therapy and family intervention in early psychosis: systematic review

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Bird, Victoria, Premkumar, Preethi, Kendall, Tim, Whittington, Craig, Mitchell, Jonathan, Kuipers, Elizabeth·2010·British Journal of Psychiatry

Abstract

Background: Early intervention services for psychosis aim to detect emergent symptoms, reduce the duration of untreated psychosis, and improve access to effective treatments. Aims: To evaluate the effectiveness of early intervention services, cognitive–behavioural therapy (CBT) and family intervention in early psychosis. Method: Systematic review and meta-analysis of randomised controlled trials of early intervention services, CBT and family intervention for people with early psychosis. Results: Early intervention services reduced hospital admission, relapse rates and symptom severity, and improved access to and engagement with treatment. Used alone, family intervention reduced relapse and hospital admission rates, whereas CBT reduced the severity of symptoms with little impact on relapse or hospital admission. Conclusions: For people with early psychosis, early intervention services appear to have clinically important benefits over standard care. Including CBT and family intervention within the service may contribute to improved outcomes in this critical period. The longer-term benefits of this approach and its component treatments for people with early and established psychosis need further research.

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  1. [18]Ventura J, Lukoff KH, Neuchterlein KH, Liberman RP, Green MF, Shaner A. Manual for the Expanded Brief Psychiatric Rating Scale. Int J Methods Psychiatr Res 1993; 3: 227–44.
  2. [27]Wang C, Li Y, Zhao Z, Pan M, Feng Y, Sun F, et al. Controlled study on long-term effect of cognitive behavior intervention on first episode schizophrenia. Chinese Ment Health J 2003; 17: 200–2.

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Authors
Bird, V., Premkumar, P., Kendall, T., Whittington, C., Mitchell, J., & Kuipers, E.
Affiliations
  • Centre for Mental Health (GB)
  • King's College London (GB)
  • Royal College of Psychiatrists (GB)
  • University College London (GB)
  • Sheffield Health and Social Care NHS Foundation Trust (GB)
Corresponding author
Bird, Victoria
Venue
British Journal of Psychiatry
Published
2010-11
Volume
197
Issue
5
Pages
350-356
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
OpenAlex
W2135059788
Cited by
468
References
60
Citations by year
2026: 20 · 2025: 19 · 2024: 28 · 2023: 30 · 2022: 21 · 2021: 28 · 2020: 39 · 2019: 40 · 2018: 39 · 2017: 35 · 2016: 31 · 2015: 34 · 2014: 34 · 2013: 33 · 2012: 22
FWCI
3.09
Type
journal article
Language
en
Open access
Locations
  • The British Journal of Psychiatry (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • Nottingham Trent University's Institutional Repository (Nottingham Trent Repository) (submittedVersion)
  • Research Portal (King's College London) (submittedVersion, cc-by-nc)
  • Queen Mary Research Online (Queen Mary University of London) (submittedVersion, cc-by-nc)
Funders
Wellcome Trust (067427/z/02/z.)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Clinical Psychology › Counseling, Therapy, and Family Dynamics
  • Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
Keywords
early psychosis, early intervention services, cognitive behavioral therapy, family intervention, relapse, hospitalization, symptom severity, treatment engagement, duration of untreated psychosis
MeSH terms
Family Therapy, Hospitalization, Humans, Mental Health Services, Patient Acceptance of Health Care, Psychiatric Status Rating Scales, Psychotic Disorders, Severity of Illness Index, Time Factors, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome, Early Diagnosis, Secondary Prevention

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