Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value

Research domain criteria (RDoC): toward a new classification framework for research on mental disorders

Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S., Quinn, K., Sanislow, C., & Wang, P. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09091379 · Cited by 7,067 · see citing works

Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors

Berk, M., Kapczinski, F., Andreazza, A. C., Dean, O. M., Giorlando, F., Maes, M., Yücel, M., Gama, C. S., Dodd, S., Dean, B., et al. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.001 · Cited by 1,178 · see citing works

Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions

McGorry, P. D., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2006) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2006.01860.x · Cited by 919 · see citing works

Cognitive–behavioural therapy for severe and recurrent bipolar disorders: Randomised controlled trial

Scott, J., Paykel, E., Morriss, R., Bentall, R., Kinderman, P., Johnson, T., Abbott, R., & Hayhurst, H. (2006) · British Journal of Psychiatry · doi:10.1192/bjp.188.4.313 · Cited by 566 · see citing works

Can bipolar disorder be viewed as a multi-system inflammatory disease?

Leboyer, M., Soreca, I., Scott, J., Frye, M., Henry, C., Tamouza, R., & Kupfer, D. J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.12.049 · Cited by 417 · see citing works

Clinical implications of a staging model for bipolar disorders

Kapczinski, F. P., Dias, V. V., Kauer‐Sant’Anna, M., Frey, B. N., Grassi‐Oliveira, R., Colom, F., & Berk, M. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.31 · Cited by 263 · see citing works

Staging: a neglected dimension in psychiatric classification

Fava, G. A., & Kellner, R. (1993) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1993.tb03362.x · Cited by 252 · see citing works

Setting the stage: from prodrome to treatment resistance in bipolar disorder

Berk, M., Conus, P., Lucas, N., Hallam, K. T., Malhi, G. S., Dodd, S., Yatham, L. N., Yung, A. R., & McGorry, P. D. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00484.x · Cited by 239 · see citing works

Applying clinical staging to young people who present for mental health care

Hickie, I. B., Scott, E. M., Hermens, D. F., Naismith, S. L., Guastella, A. J., Kaur, M., Sidis, A., Whitwell, B., Glozier, N., Davenport, T., et al. (2013) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2012.00366.x · Cited by 229 · see citing works

Frontal lobe changes occur early in the course of affective disorders in young people

Lagopoulos, J., Hermens, D. F., Naismith, S. L., Scott, E. M., & Hickie, I. B. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-4 · Cited by 51 · see citing works

Cognitive-Behavioural Therapy for Severe and Recurrent Bipolar Disorders: Randomised Controlled Trial

Scott, J. L., Paykel, E. S., Morriss, R. K., Bentall, R. P., Kinderman, P., Johnson, T. L., Abbott, R., & Hayhurst, H. (2007) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.5.1.64 · Cited by 48 · see citing works

Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated recommendations from the British Association for Psychopharmacology

Barnes, T. R. E., Drake, R., Paton, C., Cooper, S. J., Deakin, J. F. W., Ferrier, I. N., Gregory, C. J., Haddad, P. M., Howes, O. D., Jones, I. R., et al. (2019) · Journal of Psychopharmacology · doi:10.1177/0269881119889296 · Cited by 607 · see citing works

Transdiagnostic psychiatry: a systematic review

Fusar‐Poli, P., Solmi, M., Brondino, N., Davies, C., Chae, C., Politi, P., Borgwardt, S., Lawrie, S. M., Parnas, J., & McGuire, P. (2019) · World Psychiatry · doi:10.1002/wps.20631 · Cited by 409 · see citing works

Has the time come for a staging model to map the course of eating disorders from high risk to severe enduring illness? An examination of the evidence

Treasure, J., Stein, D., & Maguire, S. (2015) · Early Intervention in Psychiatry · doi:10.1111/eip.12170 · Cited by 353 · see citing works

Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management

Berk, M., Köhler‐Forsberg, O., Turner, M., Penninx, B. W. J. H., Wrobel, A., Firth, J., Loughman, A., Reavley, N. J., McGrath, J. J., Momen, N. C., et al. (2023) · World Psychiatry · doi:10.1002/wps.21110 · Cited by 336 · see citing works

Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics

Alda, M. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.4 · Cited by 317 · see citing works

Transdiagnostic clinical staging in youth mental health: a first international consensus statement

Shah, J. L., Scott, J., McGorry, P. D., Cross, S. P. M., Keshavan, M. S., Nelson, B., Wood, S. J., Marwaha, S., Yung, A. R., Scott, E. M., et al. (2020) · World Psychiatry · doi:10.1002/wps.20745 · Cited by 291 · see citing works

Youth Mental Health Should Be a Top Priority for Health Care in Canada

Malla, A., Shah, J., Iyer, S., Boksa, P., Joober, R., Andersson, N., Lal, S., & Fuhrer, R. (2018) · The Canadian Journal of Psychiatry · doi:10.1177/0706743718758968 · Cited by 232 · see citing works

Sleep in patients with remitted bipolar disorders: a meta-analysis of actigraphy studies

Geoffroy, P. A., Scott, J. L., Boudebesse, C., Lajnef, M., Henry, C., Leboyer, M., Bellivier, F., & Étain, B. (2014) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12367 · Cited by 240 · see citing works

A life span perspective on borderline personality disorder

Videler, A. C., Hutsebaut, J., Schulkens, J. E. M., Sobczak, S., & van Alphen, S. P. J. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1040-1 · Cited by 236 · see citing works

Staging systems in bipolar disorder: an <scp>I</scp>nternational <scp>S</scp>ociety for <scp>B</scp>ipolar <scp>D</scp>isorders <scp>T</scp>ask <scp>F</scp>orce <scp>R</scp>eport

Kapczinski, F., Magalhães, P. V. S., Balanzá‐Martinez, V., Dias, V. V., Frangou, S., Gama, C. S., Gonzalez‐Pinto, A., Grande, I., Ha, K., Kauer‐Sant'Anna, M., et al. (2014) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12305 · Cited by 217 · see citing works

Multisite prediction of 4-week and 52-week treatment outcomes in patients with first-episode psychosis: a machine learning approach

Koutsouleris, N., Kahn, R. S., Chekroud, A. M., Leucht, S., Falkai, P., Wobrock, T., Derks, E. M., Fleischhacker, W., & Hasan, A. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)30171-7 · Cited by 217 · see citing works

Right care, first time: a highly personalised and measurement‐based care model to manage youth mental health

Hickie, I. B., Scott, E. M., Cross, S. P., Iorfino, F., Davenport, T. A., Guastella, A. J., Naismith, S. L., Carpenter, J. S., Rohleder, C., Crouse, J. J., et al. (2019) · Medical Journal of Australia · doi:10.5694/mja2.50383 · Cited by 208 · see citing works

Clinical Stage Transitions in Persons Aged 12 to 25 Years Presenting to Early Intervention Mental Health Services With Anxiety, Mood, and Psychotic Disorders

Iorfino, F., Scott, E. M., Carpenter, J. S., Cross, S. P., Hermens, D. F., Killedar, M., Nichles, A., Zmicerevska, N., White, D., Guastella, A. J., et al. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.2360 · Cited by 188 · see citing works

Childhood Trauma in Schizophrenia: Current Findings and Research Perspectives

Popovic, D., Schmitt, A., Kaurani, L., Senner, F., Papiol, S., Malchow, B., Fischer, A., Schulze, T. G., Koutsouleris, N., & Falkai, P. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00274 · Cited by 188 · see citing works

The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research

Rizzo, L. B., Costa, L. G., Mansur, R. B., Swardfager, W., Belangero, S. I., Grassi-Oliveira, R., McIntyre, R. S., Bauer, M. E., & Brietzke, E. (2014) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.02.004 · Cited by 183 · see citing works

Depressive and anxiety disorders in concert–A synthesis of findings on comorbidity in the NESDA study

ter Meulen, W. G., Draisma, S., van Hemert, A. M., Schoevers, R. A., Kupka, R., Beekman, A. T. F., & Penninx, B. W. J. H. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.02.004 · Cited by 178 · see citing works

A systematic review and meta‐analysis of prospective transition from major depression to bipolar disorder

Ratheesh, A., Davey, C., Hetrick, S., Alvarez‐Jimenez, M., Voutier, C., Bechdolf, A., McGorry, P. D., Scott, J., Berk, M., & Cotton, S. M. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12686 · Cited by 142 · see citing works

Early intervention service systems for youth mental health: integrating pluripotentiality, clinical staging, and transdiagnostic lessons from early psychosis

Shah, J. L., Jones, N., van Os, J., McGorry, P. D., & Gülöksüz, S. (2022) · The Lancet Psychiatry · doi:10.1016/s2215-0366(21)00467-3 · Cited by 109 · see citing works

An evidence map of psychosocial interventions for the earliest stages of bipolar disorder

Vallarino, M., Henry, C., Étain, B., Gehue, L. J., Macneil, C. A., Scott, E. M., Barbato, A., Conus, P., Hlastala, S. A., Fristad, M. A., et al. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(15)00156-x · Cited by 108 · see citing works

Canadian response to need for transformation of youth mental health services: ACCESS Open Minds (Esprits ouverts)

Malla, A., Iyer, S., Shah, J., Joober, R., Boksa, P., Lal, S., Fuhrer, R., Andersson, N., Abdel‐Baki, A., Hutt‐MacLeod, D., et al. (2019) · Early Intervention in Psychiatry · doi:10.1111/eip.12772 · Cited by 107 · see citing works

Association of an Early Intervention Service for Psychosis With Suicide Rate Among Patients With First-Episode Schizophrenia-Spectrum Disorders

Chan, S. K. W., Chan, S. W. Y., Pang, H. H., Yan, K. K., Hui, C. L. M., Chang, W. C., Lee, E. H. M., & Chen, E. Y. H. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.0185 · Cited by 95 · see citing works

The etiologic, theory-based, ontogenetic hierarchical framework of alcohol use disorder: A translational systematic review of reviews.

Boness, C. L., Watts, A. L., Moeller, K. N., & Sher, K. J. (2021) · Psychological Bulletin · doi:10.1037/bul0000333 · Cited by 95 · see citing works

Five‐year follow‐up of cognitive impairment in older adults with bipolar disorder

Schouws, S. N., Comijs, H. C., Dols, A., Beekman, A. T., & Stek, M. L. (2016) · Bipolar Disorders · doi:10.1111/bdi.12374 · Cited by 90 · see citing works

A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don’t work well enough?

Dodd, S., Bauer, M., Carvalho, A. F., Eyre, H. A., D, M. F. M., Kasper, S. F., Kennedy, S. H., Khoo, J., López‐Jaramillo, C., Malhi, G. S., et al. (2020) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2020.1851052 · Cited by 95 · see citing works

Toward a Comprehensive Clinical Staging Model for Bipolar Disorder: Integrating the Evidence

Duffy, A. C. (2014) · The Canadian Journal of Psychiatry · doi:10.1177/070674371405901208 · Cited by 90 · see citing works

The Amygdala in Schizophrenia and Bipolar Disorder: A Synthesis of Structural MRI, Diffusion Tensor Imaging, and Resting-State Functional Connectivity Findings

Ho, N. F., Chong, P. L. H., Lee, D. R., Chew, Q. H., Chen, G., & Sim, K. (2019) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000207 · Cited by 89 · see citing works

Towards recovery-oriented psychosocial interventions for bipolar disorder: Quality of life outcomes, stage-sensitive treatments, and mindfulness mechanisms

Murray, G., Leitan, N. D., Thomas, N., Michalak, E. E., Johnson, S. L., Jones, S., Perich, T., Berk, L., & Berk, M. (2017) · Clinical Psychology Review · doi:10.1016/j.cpr.2017.01.002 · Cited by 87 · see citing works

All the world’s a (clinical) stage: rethinking bipolar disorder from a longitudinal perspective

Frank, E., Nimgaonkar, V. L., Phillips, M. L., & Kupfer, D. J. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.71 · Cited by 87 · see citing works

Pluripotential Risk and Clinical Staging: Theoretical Considerations and Preliminary Data From a Transdiagnostic Risk Identification Approach

Hartmann, J., McGorry, P. D., Destrée, L., Amminger, G. P., Chanen, A. M., Davey, C. G., Ghieh, R., Polari, A. R., Ratheesh, A., Yuen, H. P., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.553578 · Cited by 86 · see citing works

Is the Clinical High-Risk State a Valid Concept? Retrospective Examination in a First-Episode Psychosis Sample

Shah, J. L., Crawford, A., Mustafa, S., Iyer, S. N., Joober, R., & MALLA, A. K. (2017) · Psychiatric Services · doi:10.1176/appi.ps.201600304 · Cited by 80 · see citing works

At-risk studies and clinical antecedents of psychosis, bipolar disorder and depression: a scoping review in the context of clinical staging

Hartmann, J., Nelson, B., Ratheesh, A., Treen, D., & McGorry, P. D. (2018) · Psychological Medicine · doi:10.1017/s0033291718001435 · Cited by 79 · see citing works

The role of rumination in illness trajectories in youth: linking trans-diagnostic processes with clinical staging models

Grierson, A. B., Hickie, I. B., Naismith, S. L., & Scott, J. L. (2016) · Psychological Medicine · doi:10.1017/s0033291716001392 · Cited by 79 · see citing works

Development of a Novel Staging Model for Affective Disorders Using Partial Least Squares Bootstrapping: Effects of Lipid-Associated Antioxidant Defenses and Neuro-Oxidative Stress

Maes, M. H. J., Moraes, J. B., Congio, A. C., Bonifácio, K. L., Barbosa, D. S., Vargas, H. O., Michelin, A. P., Carvalho, A. F., & Nunes, S. O. V. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1552-z · Cited by 69 · see citing works

Personalized medicine in psychiatry

Wium‐Andersen, I. K., Vinberg, M., Kessing, L. V., & McIntyre, R. S. (2016) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2016.1216163 · Cited by 91 · see citing works

Delayed sleep onset in depressed young people

Glozier, N., O’Dea, B., McGorry, P. D., Pantelis, C., Amminger, G. P., Hermens, D. F., Purcell, R., Scott, E. M., & Hickie, I. B. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-33 · Cited by 73 · see citing works

Online mindfulness-based intervention for late-stage bipolar disorder: pilot evidence for feasibility and effectiveness

Murray, G., Leitan, N., Berk, M., Thomas, N., Michalak, E. E., Berk, L., Johnson, S. L., Jones, S. H., Perich, T., Allen, N. B., et al. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.02.024 · Cited by 71 · see citing works

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

Byrne, E. M., Zhu, Z., Qi, T., Skene, N., Bryois, J., Pardiñas, A. F., Stahl, E. A., Smoller, J. W., Rietschel, M., Owen, M. J., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0705-9 · Cited by 72 · see citing works

Trends in Psychiatry and Psychotherapy

(2020) · Trends in Psychiatry and Psychotherapy · doi:10.47626/2237-6089 · Cited by 70 · see citing works

Methylene blue treatment for residual symptoms of bipolar disorder: Randomised crossover study

Alda, M., McKinnon, M. C., Blagdon, R. A., Garnham, J. S., MacLellan, S., O’Donovan, C., Hájek, T., Nair, C., Dursun, S. M., & MacQUEEN, G. M. (2016) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.115.173930 · Cited by 67 · see citing works

Treatment patterns and short‐term outcomes in an early intervention youth mental health service

Cross, S. P. M., Hermens, D. F., & Hickie, I. B. (2014) · Early Intervention in Psychiatry · doi:10.1111/eip.12191 · Cited by 64 · see citing works

Psychological therapy for anxiety in bipolar spectrum disorders: A systematic review

Stratford, H. J., Cooper, M. J., Di Simplicio, M., Blackwell, S. E., & Holmes, E. A. (2015) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.11.002 · Cited by 63 · see citing works

Candidate Risks Indicators for Bipolar Disorder: Early Intervention Opportunities in High-Risk Youth

Duffy, A. C., Jones, S. H., Goodday, S., & Bentall, R. P. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv071 · Cited by 61 · see citing works

Transforming youth mental health: a Canadian perspective

Iyer, S. N., Boksa, P., Lal, S., Shah, J. L., Marandola, G., Jordan, G., Doyle, M., Joober, R., & MALLA, A. K. (2015) · Irish Journal of Psychological Medicine · doi:10.1017/ipm.2014.89 · Cited by 61 · see citing works

False dogmas in mood disorders research: Towards a nomothetic network approach

Maes, M. H. J., & Stoyanov, D. (2022) · World Journal of Psychiatry · doi:10.5498/wjp.v12.i5.651 · Cited by 54 · see citing works

Clinical staging for youth at‐risk for serious mental illness

Addington, J., Liu, L., Goldstein, B. I., Wang, J., Kennedy, S. H., Bray, S., Lebel, C. A., Stowkowy, J., & MacQUEEN, G. M. (2019) · Early Intervention in Psychiatry · doi:10.1111/eip.12786 · Cited by 60 · see citing works

Clinical staging for mental disorders: a new development in diagnostic practice in mental health

Hickie, I. B., Scott, J. L., & McGorry, P. D. (2013) · The Medical Journal of Australia · doi:10.5694/mja13.10431 · Cited by 60 · see citing works

Functional impairment in adolescents and young adults with emerging mood disorders

Scott, J. L., Scott, E. M., Hermens, D. F., Naismith, S. L., Guastella, A. J., White, D., Whitwell, B. G., Lagopoulos, J., & Hickie, I. B. (2014) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.113.134262 · Cited by 60 · see citing works

Quality of life in stabilized outpatients with bipolar I disorder: Associations with resilience, internalized stigma, and residual symptoms

Post, F., Pardeller, S., Frajo-Apor, B., Kemmler, G., Sondermann, C., Hausmann, A., Fleischhacker, W. W., Mizuno, Y., Uchida, H., & Hofer, A. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.05.055 · Cited by 58 · see citing works

Staging 2.0: refining transdiagnostic clinical staging frameworks to enhance reliability and utility for youth mental health

Scott, J. L., Iorfino, F., Capon, W., Crouse, J. J., Nelson, B., Chanen, A. M., Dwyer, D., Conus, P., Bechdolf, A., Ratheesh, A., et al. (2024) · The Lancet Psychiatry · doi:10.1016/s2215-0366(24)00060-9 · Cited by 59 · see citing works

Brain-derived neurotrophic factor increase during treatment in severe mental illness inpatients

Nuernberg, G. L., de Aguiar, B. W., Bristot, G., Fleck, M. P. D. A., & da Rocha, N. S. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.227 · Cited by 56 · see citing works

Cannabis Use and Hypomania in Young People: A Prospective Analysis

Marwaha, S., Winsper, C., Bebbington, P., & Smıth, D. J. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx158 · Cited by 56 · see citing works

Early intervention for adolescents at-risk for bipolar disorder: A pilot randomized trial of Interpersonal and Social Rhythm Therapy (IPSRT)

Goldstein, T. R., Merranko, J. A., Krantz, M. L., Garcia, M., Franzen, P. L., Levenson, J. C., Axelson, D., Birmaher, B. B., & Frank, E. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.049 · Cited by 55 · see citing works

Impairments in Peripheral Blood T Effector and T Regulatory Lymphocytes in Bipolar Disorder Are Associated with Staging of Illness and Anti-cytomegalovirus IgG Levels

Maes, M. H. J., Nani, J. V. S., Noto, C. D. S., Rizzo, L. B., Hayashi, M. A. F., & Brietzke, E. M. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02110-1 · Cited by 54 · see citing works

Taking the fuel out of the fire: Evidence for the use of anti-inflammatory agents in the treatment of bipolar disorders

Ayorech, Z., Tracy, D. K., Baumeister, D., & Giaroli, G. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.12.015 · Cited by 53 · see citing works

Diagnosis, prognosis, and treatment of brief psychotic episodes: a review and research agenda

Fusar‐Poli, P., de Pablo, G. S., Rajkumar, R. P., López‐Díaz, Á., Malhotra, S., Heckers, S., Lawrie, S. M., & Pillmann, F. (2021) · The Lancet Psychiatry · doi:10.1016/s2215-0366(21)00121-8 · Cited by 52 · see citing works

Evaluating differential developmental trajectories to adolescent-onset mood and psychotic disorders

Hickie, I. B., Hermens, D. F., Naismith, S. L., Guastella, A. J., Glozier, N., Scott, J., & Scott, E. M. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-303 · Cited by 51 · see citing works

Consensus on nomenclature for clinical staging models in bipolar disorder: A narrative review from the International Society for Bipolar Disorders (ISBD) Staging Task Force

Kupka, R., Duffy, A. C., Scott, J. L., Almeida, J., Balanzá‐Martínez, V., Birmaher, B. B., Bond, D. J., Brietzke, E. M., Chendo, I., Frey, B. N., et al. (2021) · Bipolar Disorders · doi:10.1111/bdi.13105 · Cited by 49 · see citing works

The next stage for diagnosis: validity through utility

McGorry, P. D. (2013) · World Psychiatry · doi:10.1002/wps.20080 · Cited by 51 · see citing works

Resting-state fMRI signals in offspring of parents with bipolar disorder at the high-risk and ultra-high-risk stages and their relations with cognitive function

Lin, K., Shao, R., Lu, R., Chen, K., Lu, W., Li, T., Kong, J., So, K., & Xu, G. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.01.001 · Cited by 49 · see citing works

Predicting early transition from sub-syndromal presentations to major mental disorders

Cross, S. P. M., Scott, J. L., & Hickie, I. B. (2017) · BJPsych Open · doi:10.1192/bjpo.bp.117.004721 · Cited by 47 · see citing works

Do the Trajectories of Bipolar Disorder and Schizophrenia Follow a Universal Staging Model?

Duffy, A., Malhi, G. S., & Grof, P. (2017) · The Canadian Journal of Psychiatry · doi:10.1177/0706743716649189 · Cited by 46 · see citing works

The Prevalence of Negative Symptoms Across the Stages of the Psychosis Continuum

Sauvé, G., Brodeur, M. B., Shah, J. L., & Lepage, M. (2018) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000184 · Cited by 46 · see citing works

The underlying neurobiology of key functional domains in young people with mood and anxiety disorders: a systematic review

Iorfino, F., Hickie, I. B., Lee, R. S. C., Lagopoulos, J., & Hermens, D. F. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0852-3 · Cited by 44 · see citing works

A systematic review on sleep alterations anticipating the onset of bipolar disorder

Pancheri, C., Verdolini, N., Pacchiarotti, I., Samalin, L., Chiaie, R. D., Biondi, M., Carvalho, A. F., Valdes, M., Ritter, P. S., Vieta, E., et al. (2019) · European Psychiatry · doi:10.1016/j.eurpsy.2019.02.003 · Cited by 45 · see citing works

Cognitive dysfunction in a psychotropic medication-naïve, clinical high-risk sample from the ShangHai-At-Risk-for-Psychosis (SHARP) study: Associations with clinical outcomes

Cui, H., Giuliano, A. J., Zhang, T., Xu, L., Wei, Y., Tang, Y., Qian, Z., Stone, L., Li, H., Whitfield, S., et al. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.06.018 · Cited by 45 · see citing works

Early psychosis research at Orygen, The National Centre of Excellence in Youth Mental Health

Cotton, S., Filia, K., Ratheesh, A., Pennell, K., Goldstone, S. D., & McGorry, P. D. (2015) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-015-1140-0 · Cited by 44 · see citing works

A Multi-Dimensional and Integrative Approach to Examining the High-Risk and Ultra-High-Risk Stages of Bipolar Disorder

Lin, K., Xu, G., Wong, N. M. L., Wu, H., Li, T., Lu, W., Chen, K., Chen, X., Lai, B., Zhong, L., et al. (2015) · EBioMedicine · doi:10.1016/j.ebiom.2015.06.027 · Cited by 43 · see citing works

Recent Advances in Sleep-Wake Cycle and Biological Rhythms in Bipolar Disorder

Robillard, R., Naismith, S. L., & Hickie, I. B. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-013-0402-3 · Cited by 43 · see citing works

Telomere length in bipolar disorder and lithium response

Squassina, A., Pisanu, C., Corbett, N., & Alda, M. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.10.008 · Cited by 43 · see citing works

Using New and Innovative Technologies to Assess Clinical Stage in Early Intervention Youth Mental Health Services: Evaluation Study

Ospina‐Pinillos, L., Davenport, T. A., Iorfino, F., Tickell, A. M., Cross, S. P. M., Scott, E. M., & Hickie, I. B. (2018) · Journal of Medical Internet Research · doi:10.2196/jmir.9966 · Cited by 43 · see citing works

What clinical features precede the onset of bipolar disorder?

Perich, T., Lau, P., Hadzi-Pavlovic, D., Roberts, G. M. P., Frankland, A., Wright, A., Green, M. J., Breakspear, M. J., Corry, J., Radlinska, B., et al. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.01.017 · Cited by 42 · see citing works

A systematic review of gender‐specific rates of unipolar and bipolar disorders in community studies of pre‐pubertal children

Douglas, J. L., & Scott, J. L. (2013) · Bipolar Disorders · doi:10.1111/bdi.12155 · Cited by 41 · see citing works

Staging bipolar disorder: what data and what models are needed?

Kupfer, D. J., Frank, E., & Ritchey, F. C. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(15)00096-6 · Cited by 40 · see citing works

Immunological and neurotrophic markers of risk status and illness development in high-risk youth: understanding the neurobiological underpinnings of bipolar disorder

Duffy, A. C., Horrocks, J., Doucette, S., Keown‐Stoneman, C. D. G., Grof, P., Andreazza, A. C., & Young, L. T. (2014) · International Journal of Bipolar Disorders · doi:10.1186/2194-7511-2-4 · Cited by 39 · see citing works

Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders

Aas, M., Dieset, I., Mørch, R. H., Steen, N. E., Hope, S., Reponen, E. J., Laskemoen, J. F., Ueland, T., Aukrust, P., Melle, I. S., et al. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.08.007 · Cited by 38 · see citing works

Impact of Anxiety and/or Depressive Disorders and Chronic Somatic Diseases on disability and work impairment

Bokma, W. A., Batelaan, N. M., van Balkom, A. J. L. M., & Penninx, B. W. J. H. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.01.004 · Cited by 37 · see citing works

Creating an innovative youth mental health service in the United Kingdom: The Norfolk Youth Service

Wilson, J., Clarke, T., Lower, R., Ugochukwu, U., Maxwell, S., Hodgekins, J., Wheeler, K., Goff, A., Mack, R., Horne, R., et al. (2018) · Early Intervention in Psychiatry · doi:10.1111/eip.12452 · Cited by 37 · see citing works

The diagnosis that should speak its name: why it is ethically right to diagnose and treat personality disorder during adolescence

Hutsebaut, J., Clarke, S. L., & Chanen, A. M. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1130417 · Cited by 36 · see citing works

A comparison of the cumulative incidence and early risk factors for psychotic disorder in young adults in the Northern Finland Birth Cohorts 1966 and 1986

Filatova, S., Marttila, R., Koivumaa-Honkanen, H. T., Nordström, T., Veijola, J. M., Maki, P. M., Khandaker, G. M., Isohanni, M. K., Jääskeläinen, E., Moilanen, K., et al. (2016) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796016000123 · Cited by 36 · see citing works

Clinical staging models: From general medicine to mental disorders

Scott, J. L., & Henry, C. (2017) · BJPsych Advances · doi:10.1192/apt.bp.116.016436 · Cited by 35 · see citing works

Adverse effects of obesity on cognitive functions in individuals at ultra high risk for bipolar disorder: Results from the global mood and brain science initiative

McIntyre, R. S., Mansur, R. B., Lee, Y. L., Japiassú, L., Chen, K., Lu, R., Lu, W., Chen, X., Li, T., Xu, G., et al. (2017) · Bipolar Disorders · doi:10.1111/bdi.12491 · Cited by 34 · see citing works

Designing a range of mentalizing interventions for young people using a clinical staging approach to borderline pathology

Hutsebaut, J., Debbané, M., & Sharp, C. (2020) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-020-0121-4 · Cited by 34 · see citing works

M c L ean O n T rack: a transdiagnostic program for early intervention in first‐episode psychosis

Shinn, A. K., Bolton, K. W., Karmacharya, R., Lewandowski, K. E., Yüksel, Ç., Baker, J. T., Chouinard, V., Pingali, S. M., Bye, H., Cederbaum, K., et al. (2015) · Early Intervention in Psychiatry · doi:10.1111/eip.12299 · Cited by 33 · see citing works

Prodrome or risk syndrome: what’s in a name?

Geoffroy, P. A., & Scott, J. L. (2017) · International Journal of Bipolar Disorders · doi:10.1186/s40345-017-0077-5 · Cited by 33 · see citing works

The identification of biomarkers predicting acute and maintenance lithium treatment response in bipolar disorder: A plea for further research attention

Fornaro, M., Berardis, D. D., Anastasia, A., Novello, S., Fusco, A., Cattaneo, C. I., Solmi, M., Monaco, F., Veronese, N., Kim, Y., et al. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.08.034 · Cited by 33 · see citing works

Study protocol for a prospective cohort study examining the predictive potential of dynamic symptom networks for the onset and progression of psychosis: the Mapping Individual Routes of Risk and Resilience (Mirorr) study

Booij, S. H., Wichers, M., de Jonge, P., Sytema, S., van Os, J., Wunderink, L., & Wigman, J. T. W. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-019059 · Cited by 32 · see citing works

Challenges and developments in research of the early stages of bipolar disorder

Brietzke, E. M., Rosa, A. R., Pedrini, M., Noto, M. N., Kapczinski, F. P., & Scott, J. L. (2016) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2016-1975 · Cited by 31 · see citing works

Using Staged Care to Provide “Right Care First Time” to People With Common Affective Disorders

Sawrikar, V., Stewart, E. M., LaMonica, H. M., Iorfino, F., Davenport, T. A., Cross, S. P. M., Scott, E. M., Naismith, S. L., Mowszowski, L., Guastella, A. J., et al. (2021) · Psychiatric Services · doi:10.1176/appi.ps.202000145 · Cited by 31 · see citing works

Individualized prediction of three- and six-year outcomes of psychosis in a longitudinal multicenter study: a machine learning approach

de Nijs, J., Burger, T. J., Janssen, R. J., Kia, S. M., van Opstal, D. P. J., de Koning, M. B., de Haan, L., GROUP investigators, Alizadeh, B. Z., Bartels‐Velthuis, A. A., et al. (2021) · Schizophrenia · doi:10.1038/s41537-021-00162-3 · Cited by 31 · see citing works

Neuroticism and facial emotion recognition in healthy adults

Petrović, S. A., Marić, N. P., Knežević, G., Mihaljevic, M. M., Mirjanić, T., Velthorst, E., & van Os, J. (2015) · Early Intervention in Psychiatry · doi:10.1111/eip.12212 · Cited by 30 · see citing works

Clinical characteristics and influence of childhood trauma on the prodrome of bipolar disorder

Noto, M. N., Noto, C. D. S., Caribé, A. C., Miranda‐Scippa, Â., Nunes, S. O. V., Chaves, A. C., Amino, D., Grassi‐Oliveira, R., Correll, C. U., & Brietzke, E. M. (2015) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2014-1641 · Cited by 30 · see citing works

Using Digital Technologies to Facilitate Care Coordination Between Youth Mental Health Services: A Guide for Implementation

Iorfino, F., Piper, S. E., Prodan, A., LaMonica, H. M., Davenport, T. A., Lee, G. Y., Capon, W., Scott, E. M., Occhipinti, J., & Hickie, I. B. (2021) · Frontiers in Health Services · doi:10.3389/frhs.2021.745456 · Cited by 29 · see citing works

Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia

Scott, E. M., Hermens, D. F., White, D., Naismith, S. L., Gehue, J., Whitwell, B. G., Glozier, N., & Hickie, I. B. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-007066 · Cited by 29 · see citing works

Between wellness, relapse, and remission: Stages of illness in anorexia nervosa

Steinglass, J. E., Glasofer, D. R., Dalack, M., & Attia, E. (2020) · International Journal of Eating Disorders · doi:10.1002/eat.23237 · Cited by 28 · see citing works

The identification of a risk profile for young people with borderline personality pathology: a review of recent literature

Hutsebaut, J., & Aleva, A. (2020) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2020.06.004 · Cited by 28 · see citing works

Illness, at-risk and resilience neural markers of early-stage bipolar disorder

Lin, K., Shao, R., Geng, X., Chen, K., Lu, R., Gao, Y., Bi, Y., Lu, W., Guan, L., Kong, J., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.05.017 · Cited by 27 · see citing works

Strategies and foundations for scientific discovery in longitudinal studies of bipolar disorder

McInnis, M. G., Andreassen, O. A., Andreazza, A. C., Alon, U., Berk, M., Brister, T. S., Burdick, K. E., Cui, D., Frye, M. A., Leboyer, M., et al. (2022) · Bipolar Disorders · doi:10.1111/bdi.13198 · Cited by 26 · see citing works

Differential impact of current diagnosis and clinical stage on attendance at a youth mental health service

Cross, S. P. M., Hermens, D. F., Scott, J. L., Salvador‐Carulla, L., & Hickie, I. B. (2016) · Early Intervention in Psychiatry · doi:10.1111/eip.12319 · Cited by 26 · see citing works

Sleep–wake cycle phenotypes in young people with familial and non‐familial mood disorders

Scott, J. L., Naismith, S. L., Grierson, A. B., Carpenter, J. S., Hermens, D. F., Scott, E. M., & Hickie, I. B. (2016) · Bipolar Disorders · doi:10.1111/bdi.12450 · Cited by 26 · see citing works

Differences in cognitive deficits in individuals with subthreshold syndromes with and without family history of bipolar disorder

Lin, K., Lu, R., Chen, K., Li, T., Lu, W., Kong, J., & Xu, G. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.05.005 · Cited by 26 · see citing works

Clinical staging models: From general medicine to mental disorders

Scott, J. L., & Henry, C. (2017) · BJPsych Advances · doi:10.1192/apt.bp.116.016436 · Cited by 35 · see citing works

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Bélteczki, Z., Kocsis, C., van der Wijk, I., & Rihmer, Z. (2023) · PubMed

Clinical staging: a heuristic model for psychiatry and youth mental health

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Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions

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Staging in bipolar disorder: from theoretical framework to clinical utility

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