The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Historical perspective: phosphatidylserine and phosphatidylethanolamine from the 1800s to the present
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
PSS1 and PSS2 use PE as a substrate to produce PS in the endoplasmic reticulum.
“PSS1 and PSS2 (gene names: Ptdss1 and Ptdss2, respectively) use phosphatidylethanolamine (PE) as a substrate to produce PS in the endoplasmic reticulum (ER) (2, 3).”
From Molecular insights into human phosphatidylserine synthase 2 and its regulation of SREBP pathways (2025) · cites this paper as [2]
Our copy says PS synthase-2 uses PE to make PS and places the active sites of both synthases on the cytosolic face of the ER. It does not support the claim that PSS1 also uses PE; the passage describing PSS1 instead distinguishes PC exchange from PSS2’s PE-to-PS activity. The supplied passages are labeled Abstract and have no page numbers. (LLM, conf=0.88)
Experimental — accuracy not yet measuredPSS2 is an endoplasmic reticulum-associated enzyme that utilizes PE as a substrate.
“As an ER-associated enzyme that utilizes PE as a substrate”
From Molecular insights into human phosphatidylserine synthase 2 and its regulation of SREBP pathways (2025) · cites this paper as [2]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
de Brito, O. M., & Scorrano, L. (2008) · Nature · doi:10.1038/nature07534 · Cited by 2,442
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
Baysal, B. E., Ferrell, R. E., Willett-Brozick, J. E., Lawrence, E. C., Myssiorek, D., Bosch, A., Mey, A. V. D., Taschner, P. E. M., Rubinstein, W. S., Myers, E. N., et al. (2000) · Science · doi:10.1126/science.287.5454.848 · Cited by 1,638
An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen
Kornmann, B., Currie, E., Collins, S. R., Schuldiner, M., Nunnari, J., Weissman, J. S., & Walter, P. (2009) · Science · doi:10.1126/science.1175088 · Cited by 1,275
Identification of Tim4 as a phosphatidylserine receptor
Miyanishi, M., Tada, K., Koike, M., Uchiyama, Y., Kitamura, T., & Nagata, S. (2007) · Nature · doi:10.1038/nature06307 · Cited by 1,180
Endoplasmic reticulum-mitochondria contacts: Function of the junction
Rowland, A. A., & Voeltz, G. K. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3440 · Cited by 1,018 · cited 1×
“MAMs are required not only for PS import into mitochondria and the decarboxylation of PS to PE [reviewed in (105, 130, 145)], but also for regulation of calcium homeostasis because calcium transport between the ER and mitochondria occurs via MAMs (99, 131, 146).”
BackgroundMitochondrial Dysfunction in Neurodegenerative Diseases
Johri, A., & Beal, M. F. (2012) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.112.192138 · Cited by 806
ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells
Lewis, S. C., Uchiyama, L. F., & Nunnari, J. (2016) · Science · doi:10.1126/science.aaf5549 · Cited by 673
Upregulated function of mitochondria‐associated ER membranes in Alzheimer disease
Area‐Gomez, E., del Carmen Lara Castillo, M., Tambini, M. D., Guardia‐Laguarta, C., de Groof, A. J. C., Madra, M., Ikenouchi, J., Umeda, M., Bird, T. D., Sturley, S. L., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.202 · Cited by 638
Tubbs, E., Theurey, P., Vial, G., Bendridi, N., Bravard, A., Chauvin, M.-A., Ji-Cao, J., Zoulim, F., Bartosch, B., Ovize, M., et al. (2014) · Diabetes · doi:10.2337/db13-1751 · Cited by 411
Stone, S. J., Levin, M. C., Zhou, P., Han, J., Walther, T. C., & Farese, R. V. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m805768200 · Cited by 390
Jin, X.-H., Okamoto, Y., Morishita, J., Tsuboi, K., Tonai, T., & Ueda, N. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m606369200 · Cited by 155
OHSAWA, T., NISHIJIMA, M., & KUGE, O. (2004) · Biochemical Journal · doi:10.1042/bj20040443 · Cited by 28
Flagged first, then by citations
Research works printed but not linked: 282
- Danielli, 1935, A contribution to the theory of permeability of thin films, J. Cell. Comp. Physiol., 5, 495, 10.1002/jcp.1030050409 · DOI
- Singer, 1972, The fluid mosaic model of the structure of cell membranes, Science., 175, 720, 10.1126/science.175.4023.720 · DOI
- Simons, 1997, Functional rafts in cell membranes, Nature., 387, 569, 10.1038/42408 · DOI · Paper page
- Berridge, 1984, Inositol trisphosphate, a novel second messenger in cellular signal transduction, Nature., 312, 315, 10.1038/312315a0 · DOI · Paper page
- Nishizuka, 1992, Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C, Science., 258, 607, 10.1126/science.1411571 · DOI
- Kimura, 2013, Phosphatidylserine synthase-2: high efficiency for synthesizing phosphatidylserine containing docosahexaenoic acid, J. Lipid Res., 54, 214, 10.1194/jlr.M031989 · DOI
- Kim, 2007, Novel metabolism of docosahexaenoic acid in neural cells, J. Biol. Chem., 282, 18661, 10.1074/jbc.R700015200 · DOI
- Schick, 1976, Location of phosphatidylethanolamine and phosphatidylserine in the human platelet plasma membrane, J. Clin. Invest., 57, 1221, 10.1172/JCI108390 · DOI
- Op den Kamp, 1979, Lipid asymmetry in membranes, Annu. Rev. Biochem., 48, 47, 10.1146/annurev.bi.48.070179.000403 · DOI
- Deuel, 1957, The Lipids: Their Chemistry and Biochemistry, Interscience Publishers, Inc., New York.
- Vauquelin, 1812, Analyse de la matière cérébrale de l'homme et de quelques animaux, Ann. Chim., 81, 37
- Gobley, 1846, Recherches chimiques sur le jaune d'oed, J. Pharm. Chim., 9, 1
- Diakonow, 1868, Ueber die chemische Constitution des Lecithin [On the chemical constitution of lecithin], Zentr. Med. Wiss., 6, 2
- Thudichum, 1868, Researches on the chemical constitution of the brain, Report of the Medical Officer of the Privy Council and Local Government Board (n.s.) London., 3, 113
- Thudichum, 1884, A Treatise on the Chemical Constitution of Brain, Balliere. Tindall, and Cox, London.
- Thudicum, 1901, obituary, Nature., 64, 527
- Thudicum, 1901, obituary, The Times.
- Taurog, 1944, The choline- and non-choline-containing phospholipids of plasma, J. Biol. Chem., 156, 385, 10.1016/S0021-9258(18)51118-2 · DOI
- Renall, 1913, Über den stickstoffhältigen Bestandteil des Kephalins, Biochem. Zeitschr., 55, 296
- Levene, 1924, Synthetic lecithins, J. Biol. Chem., 60, 677, 10.1016/S0021-9258(18)85195-X · DOI
- Grun, 1927, Synthese der Kephaline, Eur. J. Inorg. Chem., 60, 151
- Folch, 1941, Isolation of phosphatidylserine from brain cephalin, and identification of the serine component, J. Biol. Chem., 139, 973, 10.1016/S0021-9258(18)72967-0 · DOI
- Folch, 1959, A simple method for the isolation and purification of total lipids from animal tissues, J. Biol. Chem., 226, 495
- Artom, 1945, A quantitative method for ethanolamine and serine as a basis for the determination of phosphatidyl ethanolamine and phosphatidyl serine in tissues, J. Biol. Chem., 157, 585, 10.1016/S0021-9258(18)51092-9 · DOI
- MacArthur, 1914, Brain cephalin: I. Distribution of the nitrogeneous hydrolysis products of cephalin, J. Am. Chem. Soc., 36, 2397, 10.1021/ja02188a017 · DOI
- Folch, 1941, An amino acid constituent of ox brain cephalin, J. Biol. Chem., 137, 51, 10.1016/S0021-9258(18)72976-1 · DOI
- Chargaff, 1942, A study of the nitrogenous constitutents of tissue phosphatides, J. Biol. Chem., 144, 343, 10.1016/S0021-9258(18)72515-5 · DOI
- Artom, 1945, Some data on the distribution of individual phospholipids in rat tissues and in human plasma, J. Biol. Chem., 157, 595, 10.1016/S0021-9258(18)51093-0 · DOI
- Nord, 1919, Ueber die katalytische Hydrierung von Cholesterin und Cholesterylen, Biochem. Zeitschr., 99, 281
- Borkenhagen, 1961, Enzymatic formation and decarboxylation of phosphatidylserine, J. Biol. Chem., 236, PC28, 10.1016/S0021-9258(19)63319-3 · DOI
- Chaikoff, 1942, The application of labeling agents to the study of phospholipid metabolism, Physiol. Rev., 22, 291, 10.1152/physrev.1942.22.4.291 · DOI
- Sinclair, 1935, The metabolism of the phospholipids: VIII. the passage of elaidic acid into tissue phospholipids. Evidence of the intermediary role of liver phospholipid into fat metabolism, J. Biol. Chem., 111, 515, 10.1016/S0021-9258(18)75052-7 · DOI
- Schoenheimer, 1937, Deuterium as an indicator in the study of intermediary metabolism: XI. Further studies on the biological uptake of deuterium into organic substances, with special reference to fat and cholesterol formation, J. Biol. Chem., 121, 235, 10.1016/S0021-9258(18)74342-1 · DOI
- Bloch, 1965, The biological synthesis of cholesterol, Science., 150, 19, 10.1126/science.150.3692.19 · DOI
- Cornforth, 1957, Studies on the biosynthesis of cholesterol. IV. Degradation of rings C and D, Biochem. J., 65, 94, 10.1042/bj0650094 · DOI
- Cavanagh, 1939, A study of the passage of fatty acids of food into lipins and glycerides of the body using deuterium as an indicator, Biochem. J., 33, 17, 10.1042/bj0330017 · DOI
- Stevens, 1951, Incorporation of short chain fatty acids into phospholipides by the rat, J. Biol. Chem., 193, 465, 10.1016/S0021-9258(18)50902-9 · DOI
- Artom, 1945, Some data on the distribution of individual phospholipids in rat tissues and human plasma, J. Biol. Chem., 157, 601, 10.1016/S0021-9258(18)51093-0 · DOI
- Fishler, 1941, The synthesis and breakdown of liver phospholipids in vitro with radioactive phosphorus as indicator, J. Biol. Chem., 141, 809, 10.1016/S0021-9258(18)72753-1 · DOI
- Stetten, 1941, Biological relationships of choline, ethanolamine, and related compounds, J. Biol. Chem., 138, 437, 10.1016/S0021-9258(18)51449-6 · DOI
- Kornberg, 1953, Enzymatic esterification of alpha-glycerophosphate by long chain fatty acids, J. Biol. Chem., 204, 345, 10.1016/S0021-9258(18)66143-5 · DOI
- Rodbell, 1955, Lecithin synthesis in liver, J. Biol. Chem., 214, 607, 10.1016/S0021-9258(18)70909-5 · DOI
- Kennedy, 1956, The function of cytidine coenzymes in the biosynthesis of phospholipides, J. Biol. Chem., 222, 193, 10.1016/S0021-9258(19)50785-2 · DOI
- Kalckar, 1954, Nonoxidative and nonproteolytic enzymes; biosynthesis and metabolism of phosphorus compounds, Annu. Rev. Biochem., 23, 527, 10.1146/annurev.bi.23.070154.002523 · DOI
- Kennedy, 1956, New synthesis of lecithin in an isolated enzyme system, Nature., 178, 594, 10.1038/178594a0 · DOI
- Weiss, 1958, The enzymatic formation of lecithin from cytidine diphosphate choline and D-1,2-diglyceride, J. Biol. Chem., 231, 53, 10.1016/S0021-9258(19)77284-6 · DOI
- Kennedy, 1957, Metabolism of lipides, Annu. Rev. Biochem., 26, 119, 10.1146/annurev.bi.26.070157.001003 · DOI
- Folch, 1948, The chemical structure of phosphatidyl serine, J. Biol. Chem., 174, 439, 10.1016/S0021-9258(18)57326-9 · DOI
- Baer, 1955, Phosphatidylserine, J. Biol. Chem., 212, 25, 10.1016/S0021-9258(18)71090-9 · DOI
- Hubscher, 1959, Studies on the biosynthesis of phosphatidylserine, Biochim. Biophys. Acta., 36, 518, 10.1016/0006-3002(59)90194-5 · DOI
- Kanfer, 1964, Metabolism and function of bacterial lipids. II. Biosynthesis of lipids in Escherichia coli, J. Biol. Chem., 239, 1720, 10.1016/S0021-9258(18)91247-0 · DOI
- Gardner, 1999, A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes, J. Biol. Chem., 274, 31671, 10.1074/jbc.274.44.31671 · DOI
- Ansell, 1966, The incorporation of the phosphate esters of N-substituted aminoethanols into the phospholipids of brain and liver, Biochem. J., 98, 303, 10.1042/bj0980303 · DOI
- Spanner, 1982, Activation of glycerophosphocholine phosphodiesterase in rat forebrain by Ca2+, Biochem. J., 208, 845, 10.1042/bj2080845 · DOI
- Barańska, 1982, Biosynthesis and transport of phosphatidylserine in the cell, Adv. Lipid Res., 19, 163, 10.1016/B978-0-12-024919-0.50011-4 · DOI
- Suzuki, 1985, Purification and properties of an ethanolamine-serine base exchange enzyme of rat brain microsomes, J. Biol. Chem., 260, 1394, 10.1016/S0021-9258(18)89604-1 · DOI
- Kuge, 1985, Isolation of a somatic cell mutant defective in phosphatidylserine biosynthesis, Proc. Natl. Acad. Sci. USA., 82, 1926, 10.1073/pnas.82.7.1926 · DOI
- Voelker, 1986, Isolation and characterization of a Chinese hamster ovary cell line requiring ethanolamine or phosphatidylserine for growth and exhibiting defective phosphatidylserine synthase activity, J. Biol. Chem., 261, 1002, 10.1016/S0021-9258(17)36044-1 · DOI
- Kuge, 1997, Phosphatidylserine synthase I and II of mammalian cells, Biochim. Biophys. Acta., 1348, 151, 10.1016/S0005-2760(97)00137-9 · DOI · Paper page
- Kuge, 1997, Cloning of a Chinese hamster ovary (CHO) cDNA encoding phosphatidylserine synthase (PSS) II, overexpression of which suppresses the phosphatidylserine biosynthetic defect of a PSS I-lacking mutant of CHO-K1 cells, J. Biol. Chem., 272, 19133, 10.1074/jbc.272.31.19133 · DOI
- Kuge, 1991, A Chinese hamster cDNA encoding a protein essential for phosphatidylserine synthase I activity, J. Biol. Chem., 266, 24184, 10.1016/S0021-9258(18)54410-0 · DOI
- Stone, 1999, Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2, Biochem. J., 342, 57, 10.1042/bj3420057 · DOI
- Kuge, 2003, Purification and characterization of Chinese hamster phosphatidylserine synthase 2, J. Biol. Chem., 278, 42692, 10.1074/jbc.M307270200 · DOI
- Sturbois-Balcerzak, 2001, Structure and expression of the murine phosphatidylserine synthase-1 gene, J. Biol. Chem., 276, 8205, 10.1074/jbc.M009776200 · DOI
- Bergo, 2002, Defining the importance of phosphatidylserine synthase 2 in mice, J. Biol. Chem., 277, 47701, 10.1074/jbc.M207734200 · DOI
- Stone, 1998, Cloning and expression of mouse liver phosphatidylserine synthase-1 cDNA: overexpression in rat hepatoma cells inhibits the CDP-ethanolamine pathway for phosphatidylethanolamine biosynthesis, J. Biol. Chem., 273, 7293, 10.1074/jbc.273.13.7293 · DOI
- Jelsema, 1978, Distribution of phospholipid biosynthetic enzymes among cell components of rat liver, J. Biol. Chem., 253, 7960, 10.1016/S0021-9258(17)34464-2 · DOI
- Saito, 1996, Immunochemical identification of the pssA gene product as phosphatidylserine synthase I of Chinese hamster ovary cells, FEBS Lett., 395, 262, 10.1016/0014-5793(96)01049-6 · DOI
- Vance, 1990, Phospholipid synthesis in a membrane fraction associated with mitochondria, J. Biol. Chem., 265, 7248, 10.1016/S0021-9258(19)39106-9 · DOI
- Saito, 1998, Genetic evidence that phosphatidylserine synthase II catalyzes the conversion of phosphatidylethanolamine to phosphatidylserine in Chinese hamster ovary cells, J. Biol. Chem., 273, 17199, 10.1074/jbc.273.27.17199 · DOI · Paper page
- Bell, 1981, Lipid topogenesis, J. Lipid Res., 22, 391, 10.1016/S0022-2275(20)34952-X · DOI
- Breslow, 1993, Transgenic mouse models of lipoprotein metabolism and atherosclerosis, Proc. Natl. Acad. Sci. USA., 90, 8314, 10.1073/pnas.90.18.8314 · DOI
- Maeda, 1994, Targeted disruption of the apolipoprotein C–III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia, J. Biol. Chem., 269, 23610, 10.1016/S0021-9258(17)31559-4 · DOI
- Vance, 2009, Physiological consequences of disruption of mammalian phospholipid biosynthetic genes, J. Lipid Res., 50, S132, 10.1194/jlr.R800048-JLR200 · DOI
- Arikketh, 2008, Defining the importance of phosphatidylserine synthase-1 (PSS1): unexpected viabliity of PSS1-deficient mice, J. Biol. Chem., 283, 12888, 10.1074/jbc.M800714200 · DOI · Paper page
- Steenbergen, 2006, Phospholipid homeostasis in phosphatidylserine synthase-2-deficient mice, Biochim. Biophys. Acta., 1761, 313, 10.1016/j.bbalip.2006.03.005 · DOI
- Kanfer, 1988, Regulation of the choline, ethanolamine and serine base exchange enzyme activities of rat brain microsomes by phosphorylation and dephosphorylation, FEBS Lett., 240, 101, 10.1016/0014-5793(88)80347-8 · DOI
- Carman, 1999, Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes, Prog. Lipid Res., 38, 361, 10.1016/S0163-7827(99)00010-7 · DOI
- Tasseva, 2011, N-Myc and SP regulate phosphatidylserine synthase-1 expression in brain and glial cells, J. Biol. Chem., 286, 1061, 10.1074/jbc.M110.158709 · DOI
- Nishijima, 1986, Phosphatidylserine biosynthesis in cultured Chinese hamster ovary cells. I. Inhibition of de novo phosphatidylserine biosynthesis by exogenous phosphatidylserine and its efficient incorporation, J. Biol. Chem., 261, 5784, 10.1016/S0021-9258(17)38450-8 · DOI
- Hasegawa, 1989, Isolation and characterization of a Chinese hamster ovary cell mutant with altered regulation of phosphatidylserine biosynthesis, J. Biol. Chem., 264, 19887, 10.1016/S0021-9258(19)47193-7 · DOI
- Kuge, 1998, Control of phosphatidylserine biosynthesis through phosphatidylserine-mediated inhibition of phosphatidylserine synthase I in Chinese hamster ovary cells, Proc. Natl. Acad. Sci. USA., 95, 4199, 10.1073/pnas.95.8.4199 · DOI
- Kuge, 1999, Control of phosphatidylserine synthase II activity in Chinese hamster ovary cells, J. Biol. Chem., 274, 23844, 10.1074/jbc.274.34.23844 · DOI
- Lenz, 1974, A generalized disorder of the connective tissues with progeria, choanal atresia, symphalangism, hypoplasia of dentine and craniodiaphyseal hypostosis, Birth Defects Orig. Artic. Ser., 10, 133
- Sousa, 2014, Gain-of-function mutations in the phosphatidylserine synthase 1 (PTDSS1) gene cause Lenz-Majewski syndrome, Nat. Genet., 46, 70, 10.1038/ng.2829 · DOI · Paper page
- Whyte, 2015, Lenz-Majewski hyperostotic dwarfism with hyperphosphoserinuria from a novel mutation in PTDSS1 encoding phosphatidylserine synthase 1, J. Bone Miner. Res., 30, 606, 10.1002/jbmr.2398 · DOI
- Sohn, 2016, Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions, Proc. Natl. Acad. Sci. USA., 113, 4314, 10.1073/pnas.1525719113 · DOI
- Piard, 2018, Cutis laxa and excessive bone growth due to de novo mutations in PTDSS1, Am. J. Med. Genet., 176, 668, 10.1002/ajmg.a.38604 · DOI
- Voelker, 1989, Phosphatidylserine translocation to the mitochondrion is an ATP-dependent process in permeabilized animal cells, Proc. Natl. Acad. Sci. USA., 86, 9921, 10.1073/pnas.86.24.9921 · DOI
- Voelker, 1989, Reconstitution of phosphatidylserine import into rat liver mitochondria, J. Biol. Chem., 264, 8019, 10.1016/S0021-9258(18)83144-1 · DOI
- Shiao, 1995, Evidence that phosphatidylserine is imported into mitochondria via a mitochondria-associated membrane and that the majority of mitochondrial phosphatidylethanolamine is derived from decarboxylation of phosphatidylserine, J. Biol. Chem., 270, 11190, 10.1074/jbc.270.19.11190 · DOI
- Bernhard, 1952, Submicroscopical structure of cytoplasmic basophils in the liver, pancreas and salivary gland; study of ultrafine slices by electron microscope, Z. Zellforsch. Mikrosk. Anat., 37, 281, 10.1007/BF00343816 · DOI
- Morré, 1971, Connections between mitochondria and endoplasmic reticulum in rat liver and onion stem, Protoplasma., 73, 43, 10.1007/BF01286410 · DOI
- Fawcett, 1955, Observations on the cytology and electron microscopy of hepatic cells, J. Natl. Cancer Inst., 15, 1475
- Franke, 1971, Outer mitochondrial membrane continuous with endoplasmic reticulum, Protoplasma., 73, 35, 10.1007/BF01286409 · DOI
- Farese, 2009, Lipid droplets finally get a little R-E-S-P-E-C-T, Cell., 139, 855, 10.1016/j.cell.2009.11.005 · DOI
- Shore, 1977, Two fractions of rough endoplasmic reticulum from rat liver, J. Cell Biol., 72, 714, 10.1083/jcb.72.3.714 · DOI
- Rizzuto, 1998, Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses, Science., 280, 1763, 10.1126/science.280.5370.1763 · DOI · Paper page
- van Golde, 1974, Biosynthesis of lipids in Golgi complex and other subcellular fractions from rat liver, Biochim. Biophys. Acta., 360, 179, 10.1016/0005-2760(74)90168-4 · DOI
- Vance, 1988, Compartmentalization of phospholipids for lipoprotein assembly on the basis of molecular species and biosynthetic origin, Biochim. Biophys. Acta., 963, 70, 10.1016/0005-2760(88)90339-6 · DOI
- Rusiñol, 1994, A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins, J. Biol. Chem., 269, 27494, 10.1016/S0021-9258(18)47012-3 · DOI
- Stone, 2000, Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes, J. Biol. Chem., 275, 34534, 10.1074/jbc.M002865200 · DOI
- Vance, 2014, MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond, Biochim. Biophys. Acta., 1841, 595, 10.1016/j.bbalip.2013.11.014 · DOI · Paper page
- Poston, 2013, In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM), J. Proteomics., 79, 219, 10.1016/j.jprot.2012.12.018 · DOI
- Lin, 2017, Fishing for key players in ER-mitochondrial contacts, J. Biol. Chem., 292, 16393, 10.1074/jbc.H117.795286 · DOI
- Cui, 1993, Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase, J. Biol. Chem., 268, 16655, 10.1016/S0021-9258(19)85468-6 · DOI
- Meier, 1981, Isolation and characterization of rough endoplasmic reticulum associated with mitochondria from normal rat liver, Biochim. Biophys. Acta., 646, 283, 10.1016/0005-2736(81)90335-7 · DOI
- Voelker, 1993, The ATP-dependent translocation of phosphatidylserine to the mitochondria is a process that is restricted to the autologous organelle, J. Biol. Chem., 268, 7069, 10.1016/S0021-9258(18)53146-X · DOI
- Ardail, 1990, Mitochondrial contact sites. Lipid composition and dynamics, J. Biol. Chem., 265, 18797, 10.1016/S0021-9258(17)30583-5 · DOI
- Loewen, 2005, A highly conserved binding site in vesicle-associated membrane protein-associated protein (VAP) for the FFAT motif of lipid-binding proteins, J. Biol. Chem., 280, 14097, 10.1074/jbc.M500147200 · DOI
- Wang, 2012, Chloroplast lipid synthesis and lipid trafficking through ER-plastid membrane contact sites, Biochem. Soc. Trans., 40, 457, 10.1042/BST20110752 · DOI
- Zinser, 1991, Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote saccharomyces cerevisiae, J. Bacteriol., 173, 2026, 10.1128/jb.173.6.2026-2034.1991 · DOI
- Schumacher, 2002, Phosphatidylserine transport to the mitochondria is regulated by ubiquitination, J. Biol. Chem., 277, 51033, 10.1074/jbc.M205301200 · DOI
- Herrera-Cruz, 2017, Over six decades of discovery and characterization of the architecture at mitochondria-associated membranes (MAMs), Adv. Exp. Med. Biol., 997, 13, 10.1007/978-981-10-4567-7_2 · DOI
- Area-Gomez, 2014, Assessing the function of mitochondria-associated ER membranes, Methods Enzymol., 547, 181, 10.1016/B978-0-12-801415-8.00011-4 · DOI
- Holthuis, 2005, Lipid traffic: floppy drives and a superhighway, Nat. Rev. Mol. Cell Biol., 6, 209, 10.1038/nrm1591 · DOI
- Shiao, 1998, A mitochondrial membrane protein is required for translocation of phosphatidylserine from mitochondria-associated membranes to mitochondria, Biochem. J., 331, 217, 10.1042/bj3310217 · DOI
- Voelker, 1985, Disruption of phosphatidylserine translocation to the mitochondria in baby hamster kidney cells, J. Biol. Chem., 260, 14671, 10.1016/S0021-9258(17)38623-4 · DOI
- Voelker, 1990, Characterization of phosphatidylserine synthesis and translocation in permeabilized animal cells, J. Biol. Chem., 265, 14340, 10.1016/S0021-9258(18)77306-7 · DOI
- Vance, 1991, Newly made phosphatidylserine and phosphatidylethanolamine are preferentially translocated between rat liver mitochondria and endoplasmic reticulum, J. Biol. Chem., 266, 89, 10.1016/S0021-9258(18)52406-6 · DOI
- Simbeni, 1991, Mitochondrial membrane contact sites of yeast. Characterization of lipid components and possible involvement in intramitochondrial translocation of phospholipids, J. Biol. Chem., 266, 10047, 10.1016/S0021-9258(18)99184-2 · DOI
- Wu, 2004, Reconstitution of phosphatidylserine transport from chemically defined donor membranes to phosphatidylserine decarboxylase 2 implicates specific lipid domains in the process, J. Biol. Chem., 279, 6635, 10.1074/jbc.M311570200 · DOI
- Kannan, 2017, Phosphatidylserine synthesis at membrane contact sites promotes its transport out of the ER, J. Lipid Res., 58, 553, 10.1194/jlr.M072959 · DOI
- Voelker, 1991, Adriamycin disrupts phosphatidylserine import into the mitochondria of permeabilized CHO-K1 cells, J. Biol. Chem., 266, 12185, 10.1016/S0021-9258(18)98878-2 · DOI
- Ardail, 1993, Involvement of mitochondrial contact sites in the subcellular compartmentalization of phospholipid biosynthetic enzymes, J. Biol. Chem., 268, 25985, 10.1016/S0021-9258(19)74483-4 · DOI
- Ardail, 1991, Involvement of contact sites in phosphatidylserine import into liver mitochondria, J. Biol. Chem., 266, 7978, 10.1016/S0021-9258(18)92926-1 · DOI
- Hayashi, 2009, MAM: more than just a housekeeper, Trends Cell Biol., 19, 81, 10.1016/j.tcb.2008.12.002 · DOI · Paper page
- Flis, 2013, Lipid transport between the endoplasmic reticulum and mitochondria, Cold Spring Harb. Perspect. Biol., 5, a013235, 10.1101/cshperspect.a013235 · DOI
- Csordás, 2006, Structural and functional features and significance of the physical linkage between ER and mitochondria, J. Cell Biol., 174, 915, 10.1083/jcb.200604016 · DOI
- de Brito, 2010, An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship, EMBO J., 29, 2715, 10.1038/emboj.2010.177 · DOI
- Levine, 2016, Signalling at membrane contact sites: two membranes come together to handle second messengers, Curr. Opin. Cell Biol., 39, 77, 10.1016/j.ceb.2016.02.011 · DOI
- Nguyen, 2012, Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance, Traffic., 13, 880, 10.1111/j.1600-0854.2012.01352.x · DOI
- Voelker, 2009, Genetic and biochemical analysis of non-vesicular lipid traffic, Annu. Rev. Biochem., 78, 827, 10.1146/annurev.biochem.78.081307.112144 · DOI
- Sugiura, 2013, MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2, Mol. Cell., 51, 20, 10.1016/j.molcel.2013.04.023 · DOI · Paper page
- Hirabayashi, 2017, ER-mitochondria tethering by PDZD8 regulates Ca(2+) dynamics in mammalian neurons, Science., 358, 623, 10.1126/science.aan6009 · DOI
- Simmen, 2005, PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis, EMBO J., 24, 717, 10.1038/sj.emboj.7600559 · DOI
- Steenbergen, 2005, Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects, J. Biol. Chem., 280, 40032, 10.1074/jbc.M506510200 · DOI
- Tasseva, 2013, Phosphatidylethanolamine deficiency in mammalian mitochondria impairs oxidative phosphorylation and alters mitochondrial morphology, J. Biol. Chem., 288, 4158, 10.1074/jbc.M112.434183 · DOI
- Tatsuta, 2014, Mitochondrial lipid trafficking, Trends Cell Biol., 24, 44, 10.1016/j.tcb.2013.07.011 · DOI
- Rizzuto, 1993, Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria, Science., 262, 744, 10.1126/science.8235595 · DOI
- Csordás, 2010, Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface, Mol. Cell., 39, 121, 10.1016/j.molcel.2010.06.029 · DOI · Paper page
- Hamasaki, 2013, Autophagosomes form at ER-mitochondria contact sites, Nature., 495, 389, 10.1038/nature11910 · DOI · Paper page
- Xue, 2017, Endoplasmic reticulum-mitochondria junction is required for iron homeostasis, J. Biol. Chem., 292, 13197, 10.1074/jbc.M117.784249 · DOI
- Area-Gomez, 2009, Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria, Am. J. Pathol., 175, 1810, 10.2353/ajpath.2009.090219 · DOI · Paper page
- Schon, 2011, Mitochondria: the next (neurode)generation, Neuron., 70, 1033, 10.1016/j.neuron.2011.06.003 · DOI · Paper page
- Zampese, 2011, Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk, Proc. Natl. Acad. Sci. USA., 108, 2777, 10.1073/pnas.1100735108 · DOI
- Pera, 2017, Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease, EMBO J., 36, 3356, 10.15252/embj.201796797 · DOI
- Guardia-Laguarta, 2014, α-Synuclein is localized to mitochondria-associated ER membranes, J. Neurosci., 34, 249, 10.1523/JNEUROSCI.2507-13.2014 · DOI · Paper page
- Vance, 2015, Phospholipid synthesis and transport in mammalian cells, Traffic., 16, 1, 10.1111/tra.12230 · DOI
- Prinz, 2014, Bridging the gap: membrane contact sites in signaling, metabolism, and organelle dynamics, J. Cell Biol., 205, 759, 10.1083/jcb.201401126 · DOI
- Phillips, 2016, Structure and function of ER membrane contact sites with other organelles, Nat. Rev. Mol. Cell Biol., 17, 69, 10.1038/nrm.2015.8 · DOI · Paper page
- Levine, 2006, Inter-organelle membrane contact sites: through a glass, darkly, Curr. Opin. Cell Biol., 18, 371, 10.1016/j.ceb.2006.06.011 · DOI
- Nascimbeni, 2017, ER-plasma membrane contact sites contribute to autophagosome biogenesis by regulating local PI3P synthesis, EMBO J., 36, 2018, 10.15252/embj.201797006 · DOI
- Chung, 2015, Intracellular transport. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts, Science., 349, 428, 10.1126/science.aab1370 · DOI
- Goto, 2016, Oxysterol-binding protein activation at endoplasmic reticulum-golgi contact sites reorganizes phosphatidylinositol 4-phosphate pools, J. Biol. Chem., 291, 1336, 10.1074/jbc.M115.682997 · DOI
- Liu, 2017, An inducible ER-Golgi tether facilitates ceramide transport to alleviate lipotoxicity, J. Cell Biol., 216, 131, 10.1083/jcb.201606059 · DOI
- Hua, 2017, VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis, J. Cell Biol., 216, 367, 10.1083/jcb.201608128 · DOI · Paper page
- Wong, 2018, Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis, Nature., 554, 382, 10.1038/nature25486 · DOI
- Vance, 2008, Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically-related aminophospholipids, J. Lipid Res., 49, 1377, 10.1194/jlr.R700020-JLR200 · DOI
- Vance, 2013, Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells, Biochim. Biophys. Acta., 1831, 543, 10.1016/j.bbalip.2012.08.016 · DOI · Paper page
- Sundler, 1974, Quantitative role of base exchange in phosphatidylethanolamine synthesis in isolated rat hepatocytes, FEBS Lett., 43, 303, 10.1016/0014-5793(74)80667-8 · DOI
- Riekhof, 2007, Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae, J. Biol. Chem., 282, 28344, 10.1074/jbc.M705256200 · DOI
- Voelker, 1984, Phosphatidylserine functions as the major precursor of phosphatidylethanolamine in cultured BHK-21 cells, Proc. Natl. Acad. Sci. USA., 81, 2669, 10.1073/pnas.81.9.2669 · DOI
- Miller, 1986, Characterization of the pathways for phosphatidylethanolamine biosynthesis in Chinese hamster ovary mutant and parental cell lines, J. Biol. Chem., 261, 9753, 10.1016/S0021-9258(18)67579-9 · DOI
- Zelinski, 1982, Phosphatidylethanolamine biosynthesis in isolated hamster heart, Can. J. Biochem., 60, 817, 10.1139/o82-102 · DOI
- Tijburg, 1989, Biosynthesis of phosphatidylethanolamine via the CDP-ethanolamine route is an important pathway in isolated rat hepatocytes, Biochem. Biophys. Res. Commun., 160, 1275, 10.1016/S0006-291X(89)80141-X · DOI
- Bleijerveld, 2007, The CDP-ethanolamine pathway and phosphatidylserine decarboxylation generate different phosphatidylethanolamine molecular species, J. Biol. Chem., 282, 28362, 10.1074/jbc.M703786200 · DOI
- Riekhof, 2006, Uptake and utilization of lyso-phosphatidylethanolamine by Saccharomyces cerevisiae, J. Biol. Chem., 281, 36588, 10.1074/jbc.M608851200 · DOI
- Bjerve, 1985, The biosynthesis of phosphatidylserine and phosphatidylethanolamine from L-[3–14C]serine in isolated rat hepatocytes, Biochim. Biophys. Acta., 833, 396, 10.1016/0005-2760(85)90096-7 · DOI
- Fullerton, 2007, Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2), Mol. Cell. Biol., 27, 3327, 10.1128/MCB.01527-06 · DOI
- Fullerton, 2009, The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice, J. Biol. Chem., 284, 25704, 10.1074/jbc.M109.023846 · DOI
- Percy, 1983, Characterization of brain phosphatidylserine decarboxylase: localization in the mitochondrial inner membrane, Arch. Biochem. Biophys., 223, 484, 10.1016/0003-9861(83)90613-6 · DOI
- Zborowski, 1983, Phosphatidylserine decarboxylase is located on the external side of the inner mitochondrial membrane, FEBS Lett., 157, 179, 10.1016/0014-5793(83)81141-7 · DOI
- Snell, 1977, Pyruvate-containing enzymes, Trends Biochem. Sci., 2, 131, 10.1016/0968-0004(77)90441-8 · DOI
- Onguka, 2015, Phosphatidylserine decarboxylase 1 autocatalysis and function does not require a mitochondrial-specific factor, J. Biol. Chem., 290, 12744, 10.1074/jbc.M115.641118 · DOI
- Li, 1988, Structural characterization of Escherichia coli phosphatidylserine decarboxylase, J. Biol. Chem., 263, 11516, 10.1016/S0021-9258(18)37988-2 · DOI
- Trotter, 1995, Phosphatidylserine decarboxylase 2 of Saccharomyces cerevisiae. Cloning and mapping of the gene, heterologous expression and creation of the null allele, J. Biol. Chem., 270, 6071, 10.1074/jbc.270.11.6071 · DOI
- Trotter, 1995, Identification of a non-mitochondrial phosphatidylserine decarboxylase activity (PSD2) in the yeast Saccharomyces cerevisiae, J. Biol. Chem., 270, 6062, 10.1074/jbc.270.11.6062 · DOI
- Friedman, 2018, Lipid homeostasis is maintained by dual targeting of the mitochondrial PE biosynthesis enzyme to the ER, Dev. Cell., 44, 261, 10.1016/j.devcel.2017.11.023 · DOI
- Shiao, 1995, Evidence for an ethanolamine cycle: differential recycling of the ethanolamine moiety of phosphatidylethanolamine derived from phosphatidylserine and ethanolamine, Biochem. J., 310, 673, 10.1042/bj3100673 · DOI
- Achleitner, 1995, Synthesis and intracellular transport of aminoglycerophospholipids in permeabilized cells of the yeast, Saccharomyces cerevisiae, J. Biol. Chem., 270, 29836, 10.1074/jbc.270.50.29836 · DOI
- Osman, 2011, Making heads or tails of phospholipids in mitochondria, J. Cell Biol., 192, 7, 10.1083/jcb.201006159 · DOI
- Sundler, 1975, Ethanolaminephosphate cytidylyltransferase. Purification and characterization of the enzyme from rat liver, J. Biol. Chem., 250, 8585, 10.1016/S0021-9258(19)40710-2 · DOI
- Rontein, 2003, Mitochondrial phosphatidylserine decarboxylase from higher plants. Functional complementation in yeast, localization in plants, and overexpression in Arabidopsis, Plant Physiol., 132, 1678, 10.1104/pp.103.023242 · DOI
- Zhou, 1998, Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast, Biochem. Biophys. Res. Commun., 242, 502, 10.1006/bbrc.1997.7993 · DOI
- Van Veldhoven, 2000, Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22, Biochim. Biophys. Acta., 1487, 128, 10.1016/S1388-1981(00)00079-2 · DOI
- Saba, 1997, The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase, J. Biol. Chem., 272, 26087, 10.1074/jbc.272.42.26087 · DOI
- Hannun, 2001, Enzymes of sphingolipid metabolism: from modular to integrative signaling, Biochemistry., 40, 4893, 10.1021/bi002836k · DOI
- Lykidis, 2001, Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway, J. Biol. Chem., 276, 2174, 10.1074/jbc.M008794200 · DOI
- Tian, 2006, Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2, J. Biol. Chem., 281, 28438, 10.1074/jbc.M605861200 · DOI
- Gustin, 2008, Testis development, fertility, and survival in ethanolamine kinase 2-deficient mice, Endocrinology., 149, 6176, 10.1210/en.2008-0584 · DOI
- Sundler, 1975, Biosynthesis of phosphatidylethanolamines and phosphatidylcholines from ethanolamine and choline in rat liver, Biochem. J., 146, 309, 10.1042/bj1460309 · DOI
- Tijburg, 1992, Ethanolamine phosphate cytidylyltransferase, Methods Enzymol., 209, 258, 10.1016/0076-6879(92)09032-X · DOI
- Cornell, 2000, Regulation of CTP:phosphocholine cytidylyltransferase by amphitropism and relocalization, Trends Biochem. Sci., 25, 441, 10.1016/S0968-0004(00)01625-X · DOI
- Lykidis, 2001, Lipid activation of CTP: phosphocholine cytidylyltransferase alpha: characterization and identification of a second activation domain, Biochemistry., 40, 494, 10.1021/bi002140r · DOI
- Cornell, 2015, CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis, Prog. Lipid Res., 59, 147, 10.1016/j.plipres.2015.07.001 · DOI
- Poloumienko, 2004, Genomic organization and differential splicing of the mouse and human Pcyt2 genes, Gene., 325, 145, 10.1016/j.gene.2003.10.005 · DOI
- Tie, 2007, Alternative splicing of CTP:phosphoethanolamine cytidylyltransferase produces two isoforms that differ in catalytic properties, J. Lipid Res., 48, 2172, 10.1194/jlr.M600536-JLR200 · DOI
- Fullerton, 2010, Complementation of the metabolic defect in CTP:phosphoethanolamine cytidylyltransferase (Pcyt2)-deficient primary hepatocytes, Metabolism., 59, 1691, 10.1016/j.metabol.2010.03.022 · DOI
- Leonardi, 2009, Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis, J. Biol. Chem., 284, 27077, 10.1074/jbc.M109.031336 · DOI
200 of 282 shown
Cited by
Sorted by citations
Long, T., Li, D., Vale, G., Jiang, Y., Schmiege, P., Yang, Z. J., McDonald, J. G., & Li, X. (2024) · Cell · doi:10.1016/j.cell.2024.08.004 · Cited by 31
Phosphatidylserine synthesis controls oncogenic B cell receptor signaling in B cell lymphoma
Omi, J., Kato, T., Yoshihama, Y., Sawada, K., Kono, N., & Aoki, J. (2024) · Journal of Cell Biology · doi:10.1083/jcb.202212074 · Cited by 18
Molecular insights into human phosphatidylserine synthase 2 and its regulation of SREBP pathways
Li, D., Chen, H., Vale, G., Elghobashi-Meinhardt, N., Hatton, A., Rong, S., McDonald, J. G., & Li, X. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2501177122 · Cited by 6
Metadata
- Authors
- Vance, J. E.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 2018
- Volume
- 59
- Issue
- 6
- Pages
- 923-944
- ISSN
- 0022-2275
- Cited by
- 113
- References
- 12
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review