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Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria
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Disruption or dysfunction of MAMs is associated with a variety of pathophysiological conditions, including neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.
“Disruption of contact between the mitochondria and ER is associated with a variety of pathophysiological conditions including neurodegenerative diseases.”
From The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs (2020) · cites this paper as [15]
Impairment or perturbation of MAM function has been implicated in several neurodegenerative disease conditions.
“While impairment or perturbation of MAM function has been implicated in several neurodegenerative disease conditions [13–20, 76], the contributing underlying mechanism(s) remain unknown.”
From The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs (2020) · cites this paper as [15]
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Cites
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Metadata
- Authors
- Area-Gomez, E., de Groof, A. J. C., Boldogh, I., Bird, T. D., Gibson, G. E., Koehler, C. M., Yu, W. H., Duff, K. E., Yaffe, M. P., Pon, L. A., & Schon, E. A.
- Venue
- The American Journal of Pathology
- Publisher
- Elsevier BV
- Published
- 2009-11
- Volume
- 175
- Issue
- 5
- Pages
- 1810-1816
- ISSN
- 0002-9440
- Cited by
- 369
- References
- 4
- Language
- en
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