Greater adipose tissue infiltration in skeletal muscle among older men of African ancestry
Open accessAbstract
CONTEXT: There is substantial variability across ethnic groups in the predisposition to obesity and associated metabolic abnormalities. Skeletal muscle fat has been identified as an important depot that increases with aging and may contribute to the development of diabetes. OBJECTIVE: We tested whether men of African ancestry have greater calf intermuscular adipose tissue (IMAT), compared to Caucasian men, and whether IMAT is associated with type 2 diabetes (T2D). DESIGN: We measured fasting serum glucose, body mass index, total body fat by dual-energy x-ray absorptiometry, and calf skeletal muscle composition by quantitative computed tomography in 1105 Caucasian and 518 Afro-Caribbean men aged 65+. RESULTS: Compared to Caucasian men, we found greater IMAT and lower sc adipose tissue in Afro-Caribbean men at all levels of total adiposity (P < 0.0001), including the subset of men matched on age and dual-energy x-ray absorptiometry total body fat percentage (P < 0.001). In addition, IMAT was 29 and 23% greater, whereas sc adipose tissue was 6 and 8% lower among Caucasian and Afro-Caribbean men with T2D, respectively, compared to men without T2D (P < 0.01). Observed differences in intermuscular and sc fat, both ethnic and between men with and without T2D, were independent of age, height, calf skeletal muscle and total adipose tissue, and lifestyle factors. CONCLUSIONS: Our analyses suggest that despite lower total adiposity, skeletal muscle fat infiltration is greater among African than among Caucasian ancestry men and is associated with T2D in both ethnic groups. Additional studies are needed to determine the mechanisms contributing to ethnic differences in skeletal muscle adiposity and to define the metabolic and health implications of this fat depot.
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Miljkovic et al. compared African-Caribbean and older white men and found that men of African ancestry had greater IMAT even when matched by age and total body fat.
“Miljkovic et al. (2009) compared African-Caribbean and older white men and found that men of African ancestry had greater IMAT even when matched by age and total body fat.”
From Myosteatosis in the Context of Skeletal Muscle Function Deficit: An Interdisciplinary Workshop at the National Institute on Aging (2020) · cites this paper as Miljkovic et al., 2009
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Cites
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus* (2002) · Diabetes Care · doi:10.2337/diacare.25.2007.s5 · Cited by 10,320 · see citing works
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (1997) · Diabetes Care · doi:10.2337/diacare.20.7.1183 · Cited by 6,220 · see citing works
Prevalence and trends in obesity among US adults, 1999–2000
Flegal, K. M. (2002) · JAMA · doi:10.1001/jama.288.14.1723 · Cited by 6,190 · see citing works
Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R., Wiedmeyer, H.-M., & Byrd-Holt, D. D. (1998) · Diabetes Care · doi:10.2337/diacare.21.4.518 · Cited by 2,703 · see citing works
Visser, M., Goodpaster, B. H., Kritchevsky, S. B., Newman, A. B., Nevitt, M., Rubin, S. M., Simonsick, E. M., Harris, T. B., & Study, F. T. H. A. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.3.324 · Cited by 1,403 · see citing works
Self-citationAttenuation of skeletal muscle and strength in the elderly: the Health ABC Study
Goodpaster, B. H., Carlson, C. L., Visser, M., Kelley, D. E., Scherzinger, A., Harris, T. B., Stamm, E., & Newman, A. B. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.6.2157 · Cited by 1,226 · see citing works
Self-citationGoodpaster, B. H., Leland Thaete, F., Simoneau, J.-A., & Kelley, D. E. (1997) · Diabetes · doi:10.2337/diacare.46.10.1579 · Cited by 1,012 · see citing works
Self-citationGoodpaster, B. H., Kelley, D. E., Thaete, F. L., He, J., & Ross, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.104 · Cited by 956 · see citing works
Self-citationMorino, K., Petersen, K. F., & Shulman, G. I. (2006) · Diabetes · doi:10.2337/db06-s002 · Cited by 853 · see citing works
Etiology of Insulin Resistance
Petersen, K. F., & Shulman, G. I. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2006.01.009 · Cited by 825 · see citing works
Estimating African American Admixture Proportions by Use of Population-Specific Alleles
Parra, E. J., Marcini, A., Akey, J., Martinson, J., Batzer, M. A., Cooper, R., Forrester, T., Allison, D. B., Deka, R., Ferrell, R. E., et al. (1998) · The American Journal of Human Genetics · doi:10.1086/302148 · Cited by 771 · see citing works
ORWOLL, E. S., Blank, J. B., Barrett-Connor, E. L., Cauley, J. A., Cummings, S. R., Ensrud, K. E., Lewis, C. E., Cawthon, P. M., Marcus, R., Marshall, L. M., et al. (2005) · Contemporary Clinical Trials · doi:10.1016/j.cct.2005.05.006 · Cited by 769 · see citing works
Self-citationObesity, Regional Body Fat Distribution, and the Metabolic Syndrome in Older Men and Women
Goodpaster, B. H., Krishnaswami, S., Harris, T. B., Katsiaras, A., Kritchevsky, S. B., Simonsick, E. M., Nevitt, M., Holvoet, P., & Newman, A. B. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.7.777 · Cited by 637 · see citing works
Self-citationLipid oxidation is reduced in obese human skeletal muscle
Kim, J.-Y., Hickner, R. C., Cortright, R. L., Dohm, G. L., & Houmard, J. A. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.5.e1039 · Cited by 634 · see citing works
Sparks, L. M., Xie, H., Koza, R. A., Mynatt, R., Hulver, M. W., Bray, G. A., & Smith, S. R. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1926 · Cited by 629 · see citing works
Goodpaster, B. H., Krishnaswami, S., Resnick, H., Kelley, D. E., Haggerty, C., Harris, T. B., Schwartz, A. V., Kritchevsky, S., & Newman, A. B. (2003) · Diabetes Care · doi:10.2337/diacare.26.2.372 · Cited by 619 · see citing works
Self-citationOverview of recruitment for the osteoporotic fractures in men study (MrOS)
Blank, J. B., Cawthon, P. M., Carrion-Petersen, M. L., Harper, L., Johnson, J., Mitson, E., & Delay, R. R. (2005) · Contemporary Clinical Trials · doi:10.1016/j.cct.2005.05.005 · Cited by 576 · see citing works
Incident Type 2 Diabetes Mellitus in African American and White Adults
Brancati, F. L., Kao, W. H. L., Folsom, A. R., Watson, R. L., & Szklo, M. (2000) · JAMA · doi:10.1001/jama.283.17.2253 · Cited by 502 · see citing works
Simoneau, J., Veerkamp, J. H., Turcotte, L. P., & Kelley, D. E. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.14.2051 · Cited by 491 · see citing works
Ethnicity, Obesity, and Risk of Type 2 Diabetes in Women
Shai, I., Jiang, R., Manson, J. E., Stampfer, M. J., Willett, W. C., Colditz, G. A., & Hu, F. B. (2006) · Diabetes Care · doi:10.2337/dc06-0057 · Cited by 479 · see citing works
Simoneau, J.-A., & Kelley, D. E. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.83.1.166 · Cited by 441 · see citing works
Bonen, A., Parolin, M. L., Steinberg, G. R., Calles‐Escandon, J., Tandon, N. N., Glatz, J. F. C., Luiken, J. J. F. P., Heigenhauser, G. J. F., & Dyck, D. J. (2004) · The FASEB Journal · doi:10.1096/fj.03-1065fje · Cited by 410 · see citing works
Kelley, D. E., & Goodpaster, B. H. (2001) · Diabetes Care · doi:10.2337/diacare.24.5.933 · Cited by 406 · see citing works
Self-citationRace, Visceral Adipose Tissue, Plasma Lipids, and Lipoprotein Lipase Activity in Men and Women
Després, J., Couillard, C., Gagnon, J., Bergeron, J., Leon, A. S., Rao, D. C., Skinner, J. S., Wilmore, J. H., & Bouchard, C. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.8.1932 · Cited by 386 · see citing works
Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue
Gallagher, D., Kuznia, P., Heshka, S., Albu, J., Heymsfield, S. B., Goodpaster, B., Visser, M., & Harris, T. B. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.4.903 · Cited by 354 · see citing works
Self-citationAbdominal fat distribution and metabolic risk factors: Effects of race
Lovejoy, J. C., de la Bretonne, J. A., Klemperer, M., & Tulley, R. T. (1996) · Metabolism · doi:10.1016/s0026-0495(96)90011-6 · Cited by 345 · see citing works
Reduced physical activity increases intermuscular adipose tissue in healthy young adults
Manini, T. M., Clark, B. C., Nalls, M. A., Goodpaster, B. H., Ploutz-Snyder, L. L., & Harris, T. B. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.377 · Cited by 332 · see citing works
Self-citationDiabetes in Ghana: a community based prevalence study in Greater Accra
Amoah, A. G. B., Owusu, S., & Adjei, S. (2002) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(01)00374-6 · Cited by 249 · see citing works
Cameron-Smith, D., Burke, L. M., Angus, D. J., Tunstall, R. J., Cox, G. R., Bonen, A., Hawley, J. A., & Hargreaves, M. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.2.313 · Cited by 243 · see citing works
Ryan, A. S., & Nicklas, B. (1999) · International Journal of Obesity · doi:10.1038/sj.ijo.0800777 · Cited by 199 · see citing works
van Harmelen, V., Dicker, A., Rydén, M., Hauner, H., Lönnqvist, F., Näslund, E. B., & Arner, P. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2029 · Cited by 188 · see citing works
Comparing Diabetes Prevalence Between African Americans and Whites of Similar Socioeconomic Status
Signorello, L. B., Schlundt, D. G., Cohen, S. S., Steinwandel, M. D., Buchowski, M. S., McLaughlin, J. K., Hargreaves, M. K., & Blot, W. J. (2007) · American Journal of Public Health · doi:10.2105/ajph.2006.094482 · Cited by 181 · see citing works
Albu, J., Kovera, A. J., Allen, L., Wainwright, M., Berk, E. S., Raja-Khan, N. T., Janumala, I., Burkey, B. F., Heshka, S., & Gallagher, D. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.6.1210 · Cited by 181 · see citing works
Skeletal muscle characteristics in sedentary black and Caucasian males
Ama, P. F. M., Simoneau, J. A., Boulay, M. R., Serresse, O., Thériault, G., & Bouchard, C. (1986) · Journal of Applied Physiology · doi:10.1152/jappl.1986.61.5.1758 · Cited by 179 · see citing works
Bunker, C. H., Patrick, A. L., Konety, B. R., Dhir, R., Brufsky, A., Vivas, C., Becich, M. J., Trump, D. L., & Kuller, L. H. (2002) · PubMed · Cited by 172 · see citing works
Self-citationDiabetes in Africans. Part 1: Epidemiology and clinical specificities
Sobngwi, E., Mauvais‐Jarvis, F., Vexiau, P., Mbanya, J. C., & Gautier, J. (2001) · PubMed · doi:10.25405/ncl.34249590 · Cited by 156 · see citing works
Reiner, A. P., Ziv, E., Lind, D. L., Nievergelt, C. M., Schork, N. J., Cummings, S. R., Phong, A., Burchard, E. G., Harris, T. B., Psaty, B. M., et al. (2005) · The American Journal of Human Genetics · doi:10.1086/428654 · Cited by 155 · see citing works
Skeletal muscle lipid oxidation and obesity: influence of weight loss and exercise.
Berggren, J. R., Boyle, K. E., Chapman, W. H., & Houmard, J. A. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00354.2007 · Cited by 151 · see citing works
Yim, J.-E., Heshka, S., Albu, J., Heymsfield, S. B., Kuznia, P., Harris, T. B., & Gallagher, D. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803621 · Cited by 147 · see citing works
Shulman, G. I. (2004) · Physiology · doi:10.1152/physiol.00007.2004 · Cited by 147 · see citing works
Miljkovic-Gacic, I., Gordon, C. L., Goodpaster, B. H., Bunker, C. H., Patrick, A. L., Kuller, L. H., Wheeler, V. W., Evans, R. W., & Zmuda, J. M. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.6.1590 · Cited by 122 · see citing works
Self-citationEffects of Dietary Fat on Muscle Substrates, Metabolism, and Performance in Athletes
VOGT, M., PUNTSCHART, A., HOWALD, H., MUELLER, B., MANNHART, C., GFELLER-TUESCHER, L., MULLIS, P., & HOPPELER, H. (2003) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000069336.30649.bd · Cited by 120 · see citing works
Simonsick, E. M., Maffeo, C. E., Rogers, S. K., Skinner, E. A., Davis, D., Guralnik, J. M., & Fried, L. P. (1997) · The Journals of Gerontology Series A · doi:10.1093/gerona/52a.5.m264 · Cited by 115 · see citing works
Muscle-associated triglyceride measured by computed tomography and magnetic resonance spectroscopy
Larson‐Meyer, D. E., Smith, S. R., Heilbronn, L. K., Kelley, D. E., Ravussin, E., Newcomer, B. R., & The Look AHEAD Adipose Research Group (2006) · Obesity · doi:10.1038/oby.2006.10 · Cited by 111 · see citing works
Association of African Genetic Admixture with Resting Metabolic Rate and Obesity Among Women
Fernández, J. R., Shriver, M. D., Beasley, T. M., Rafla‐Demetrious, N., Parra, E. J., Albu, J., Nicklas, B. J., Ryan, A. S., McKeigue, P., Hoggart, C., et al. (2003) · Obesity Research · doi:10.1038/oby.2003.124 · Cited by 107 · see citing works
Miljkovic-Gacic, I., Ferrell, R., Patrick, A., Kammerer, C., & Bunker, C. (2006) · Human Heredity · doi:10.1159/000089553 · Cited by 105 · see citing works
Self-citationEpidemiology of Type 1 and Type 2 Diabetes in Africa
Motala, A. A., Omar, M. A. K., & Pirie, F. J. (2003) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1177/174182670301000202 · Cited by 103 · see citing works
The molecular mechanism linking muscle fat accumulation to insulin resistance
Hulver, M. W., & Dohm, G. L. (2004) · Proceedings of The Nutrition Society · doi:10.1079/pns2004351 · Cited by 98 · see citing works
Skeletal muscle oxidative capacity in rats fed high-fat diet
Iossa, S., Mollica, M. P., Lionetti, L., Crescenzo, R., Botta, M., & Liverini, G. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0801844 · Cited by 91 · see citing works
Heterogeneity in the Relationship Between Ethnicity, BMI, and Fasting Insulin
Palaniappan, L. P., Carnethon, M. R., & Fortmann, S. P. (2002) · Diabetes Care · doi:10.2337/diacare.25.8.1351 · Cited by 90 · see citing works
Diabetes in a Caribbean population: epidemiological profile and implications
Hennis, A. J. M., Wu, S., Nemesure, B. B., Li, X., & Leske, M. C. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.1.234 · Cited by 89 · see citing works
Durheim, M. T., Slentz, C. A., Bateman, L. A., Mabe, S. K., & Kraus, W. E. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90397.2008 · Cited by 87 · see citing works
Racial Differences in Insulin Resistance and Mid‐Thigh Fat Deposition in Postmenopausal Women
Ryan, A. S., Nicklas, B. J., & Berman, D. M. (2002) · Obesity Research · doi:10.1038/oby.2002.47 · Cited by 79 · see citing works
Diabetes in Africa. Epidemiology of type 1 and type 2 diabetes in Africa.
Motala, A. A., Omar, M. A. K., & Pirie, F. J. (2003) · PubMed · doi:10.1097/01.hjr.0000060843.48106.31 · Cited by 78 · see citing works
Genetic markers for ancestry are correlated with body composition traits in older African Americans
Shaffer, J., Kammerer, C., Reich, D., McDonald, G., Patterson, N., Goodpaster, B., Bauer, D. C., Li, J., Newman, A., Cauley, J., et al. (2007) · Osteoporosis International · doi:10.1007/s00198-006-0316-6 · Cited by 58 · see citing works
Self-citationFatty acid oxidation in African-American and Caucasian women during physical activity
Hickner, R. C., Privette, J., McIver, K. L., & Barakat, H. A. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.6.2319 · Cited by 50 · see citing works
Diet-induced modulation of mitochondrial activity in rat muscle
Didier, L., Yerby, B., Deacon, R. W., & Gao, J. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00263.2007 · Cited by 48 · see citing works
der Merwe, M.-T. V., Panz, V., Crowther, N. J., Schlaphoff, G., Gray, I. P., Froguel, P., Joffe, B. I., & Lönnroth, P. (1999) · International Journal of Obesity · doi:10.1038/sj.ijo.0800969 · Cited by 33 · see citing works
Bower, J. F., Davis, J. M., Hao, E., & Barakat, H. A. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00194.2005 · Cited by 31 · see citing works
Barakat, H. A., Hickner, R. C., Privette, J., et al. (2002) · Metabolism · doi:10.1053/meta.2002.35589 · Cited by 24 · see citing works
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- Parra EJ, Kittles RA, Argyropoulos G, Pfaff CL, Hiester K, Bonilla C, Sylvester N, Parrish-Gause D, Garvey WT, Jin L, McKeigue PM, Kamboh MI, Ferrell RE, Pollitzer WS, Shriver MD 2001 Ancestral proportions and admixture dynamics in geographically defined African Americans living in South Carolina. Am J Phys Anthropol 114:18–29 [DOI] [PubMed] [Google Scholar]
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- Authors
- Miljkovic, I., Cauley, J. A., Petit, M. A., Ensrud, K. E., Strotmeyer, E., Sheu, Y., Gordon, C. L., Goodpaster, B. H., Bunker, C. H., Patrick, A. L., Wheeler, V. W., Kuller, L. H., Faulkner, K. A., Zmuda, J. M., & for the Osteoporotic Fractures in Men (MrOS) Research Group the Tobago Health Studies Research Group
- Affiliations
- University of Minnesota (US)
- McMaster University (CA)
- University of Pittsburgh (US)
- Tobago Health Studies Office (B.H.G., A.L.P., V.W.W.), Scarborough, Tobago, Trinidad and Tobago
- Corresponding author
- Miljkovic, Iva
- ORCID
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2009-08-01
- Volume
- 94
- Issue
- 8
- Pages
- 2735-2742
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- PMC
- PMC2730872
- OpenAlex
- W1977359934
- Cited by
- 79
- References
- 61
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 6 · 2023: 4 · 2022: 4 · 2021: 3 · 2020: 5 · 2019: 8 · 2018: 5 · 2017: 4 · 2016: 2 · 2015: 6 · 2014: 4 · 2013: 8 · 2012: 4
- FWCI
- 2.18
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (U01AG018197, U01AG027810, U01AG042140)
- National Institute of Diabetes and Digestive and Kidney Diseases (K01DK083029)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (U01AR045583, U01AR045580, R01AR049747, U01AR045632, U01AR045654, U01AR045614, U01AR045647, U01AR066160)
- National Center for Research Resources (M01RR000334)
- Topics
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- intermuscular adipose tissue, skeletal muscle fat infiltration, type 2 diabetes, Afro-Caribbean men, African ancestry, ethnic differences, subcutaneous adipose tissue, aging, older men, obesity, triceps surae
- MeSH terms
- Adipose Tissue, Aged, Aging, Body Composition, Humans, Insulin Resistance, Male, Body Mass Index, Walking, Muscle, Skeletal, Black People, White People, Adiposity
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