Roles of PDGF in animal development

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X.-F., Breitman, M. L., & Schuh, A. C. (1995) · Nature · doi:10.1038/376062a0 · Cited by 3,931

Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor

Heldin, C.-H., & Westermark, B. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.4.1283 · Cited by 2,496

PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors

Heinrich, M. C., Corless, C. L., Duensing, A., McGreevey, L., Chen, C.-J., Joseph, N., Singer, S., Griffith, D. J., Haley, A., Town, A., et al. (2003) · Science · doi:10.1126/science.1079666 · Cited by 2,301

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

Lindahl, P., Johansson, B. R., Levéen, P., & Betsholtz, C. (1997) · Science · doi:10.1126/science.277.5323.242 · Cited by 2,226

A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro

Ross, R., Glomset, J., Kariya, B., & Harker, L. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.4.1207 · Cited by 1,847

Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

Hellström, M., Kalén, M., Lindahl, P., Abramsson, A., & Betsholtz, C. (1999) · Development · doi:10.1242/dev.126.14.3047 · Cited by 1,700

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

Waterfield, M. D., Scrace, G. T., Whittle, N., Stroobant, P., Johnsson, A., Wasteson, Å., Westermark, B., Heldin, C.-H., Huang, J. S., & Deuel, T. F. (1983) · Nature · doi:10.1038/304035a0 · Cited by 1,616

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

Doolittle, R. F., Hunkapiller, M. W., Hood, L. E., Devare, S. G., Robbins, K. C., Aaronson, S. A., & Antoniades, H. N. (1983) · Science · doi:10.1126/science.6304883 · Cited by 1,536

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF

Benjamin, L. E., Hemo, I., & Keshet, E. (1998) · Development · doi:10.1242/dev.125.9.1591 · Cited by 1,265

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.

Levéen, P., Pekny, M., Gebre-Medhin, S., Swolin, B., Larsson, E., & Betsholtz, C. (1994) · Genes & Development · doi:10.1101/gad.8.16.1875 · Cited by 1,131

Neural Crest Cells Contribute to Normal Aorticopulmonary Septation

Kirby, M. L., Gale, T. F., & Stewart, D. E. (1983) · Science · doi:10.1126/science.6844926 · Cited by 1,113

Lack of Pericytes Leads to Endothelial Hyperplasia and Abnormal Vascular Morphogenesis

Hellström, M., Gerhardt, H., Kalén, M., Li, X., Eriksson, U., Wolburg, H., & Betsholtz, C. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.153.3.543 · Cited by 1,100

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

Soriano, P. (1994) · Genes & Development · doi:10.1101/gad.8.16.1888 · Cited by 989

PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis

Boström, H., Willetts, K., Pekny, M., Levéen, P., Lindahl, P., Hedstrand, H., Pekna, M., Hellström, M., Gebre-Medhin, S., Schalling, M., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81270-2 · Cited by 864

Signal transduction via platelet-derived growth factor receptors

Heldin, C.-H., Östman, A., & Rönnstrand, L. (1998) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/s0304-419x(98)00015-8 · Cited by 742

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

Dai, C., Celestino, J. C., Okada, Y., Louis, D. N., Fuller, G. N., & Holland, E. C. (2001) · Genes & Development · doi:10.1101/gad.903001 · Cited by 708

The PDGFα receptor is required for neural crest cell development and for normal patterning of the somites

Soriano, P. (1997) · Development · doi:10.1242/dev.124.14.2691 · Cited by 707

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops.

Hermanson, M., Funa, N. S., Hartman, M., Claesson, L., Heldin, C., Westermark, B., & Nistér, M. (1992) · PubMed · Cited by 705

PDGF-C is a new protease-activated ligand for the PDGF α-receptor

Li, X., Pontén, A., Aase, K., Karlsson, L., Abramsson, A., Uutela, M., Bäckström, G., Hellström, M., Boström, H., Li, H., et al. (2000) · Nature Cell Biology · doi:10.1038/35010579 · Cited by 623

LRP: Role in Vascular Wall Integrity and Protection from Atherosclerosis

Boucher, P., Gotthardt, M., Li, W.-P., Anderson, R. G. W., & Herz, J. (2003) · Science · doi:10.1126/science.1082095 · Cited by 581

PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor

Bergsten, E., Uutela, M., Li, X., Pietras, K., Östman, A., Heldin, C.-H., Alitalo, K., & Eriksson, U. (2001) · Nature Cell Biology · doi:10.1038/35074588 · Cited by 562

Extracellular matrix regulates Sertoli cell differentiation, testicular cord formation, and germ cell development in vitro.

Hadley, M. A., Byers, S. W., Suárez-Quian, C. A., Kleinman, H. K., & Dym, M. (1985) · The Journal of cell biology · doi:10.1083/jcb.101.4.1511 · Cited by 538

Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo

Calver, A. R., Hall, A. C., Yu, W.-P., Walsh, F. S., Heath, J. K., Betsholtz, C., & Richardson, W. D. (1998) · Neuron · doi:10.1016/s0896-6273(00)80469-9 · Cited by 501

Guidance of Cell Migration by the Drosophila PDGF/VEGF Receptor

Duchek, P., Somogyi, K., Jékely, G., Beccari, S., & Rørth, P. (2001) · Cell · doi:10.1016/s0092-8674(01)00502-5 · Cited by 475

Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice

Fruttiger, M., Karlsson, L., Hall, A. C., Abramsson, A., Calver, A. R., Boström, H., Willetts, K., Bertold, C.-H., Heath, J. K., Betsholtz, C., et al. (1999) · Development · doi:10.1242/dev.126.3.457 · Cited by 441

Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development

Lindahl, P., Karlsson, L., Hellström, M., Gebre-Medhin, S., Willetts, K., Heath, J. K., & Betsholtz, C. (1997) · Development · doi:10.1242/dev.124.20.3943 · Cited by 420

Pdgfr-α mediates testis cord organization and fetal Leydig cell development in the XY gonad

Brennan, J., Tilmann, C., & Capel, B. (2003) · Genes & Development · doi:10.1101/gad.1052503 · Cited by 409

PDGF-D, a new protease-activated growth factor

LaRochelle, W. J., Jeffers, M., McDonald, W. F., Chillakuru, R. A., Giese, N. A., Lokker, N. A., Sullivan, C., Boldog, F. L., Yang, M., Vernet, C., et al. (2001) · Nature Cell Biology · doi:10.1038/35074593 · Cited by 402

Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy

Enge, M. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf418 · Cited by 402

Role of neural crest in congenital heart disease.

Kirby, M. L., & Waldo, K. L. (1990) · Circulation · doi:10.1161/01.cir.82.2.332 · Cited by 382

Developmental roles of platelet‐derived growth factors

Betsholtz, C., Karlsson, L., & Lindahl, P. (2001) · BioEssays · doi:10.1002/bies.1069 · Cited by 372

Paracrine PDGF-B/PDGF-Rβ signaling controls mesangial cell development in kidney glomeruli

Lindahl, P., Hellström, M., Kalén, M., Karlsson, L., Pekny, M., Pekna, M., Soriano, P., & Betsholtz, C. (1998) · Development · doi:10.1242/dev.125.17.3313 · Cited by 365

Cooperativity between Sertoli cells and testicular peritubular cells in the production and deposition of extracellular matrix components.

Skinner, M. K., Tung, P. S., & Fritz, I. B. (1985) · The Journal of Cell Biology · doi:10.1083/jcb.100.6.1941 · Cited by 339

Abnormal gastrointestinal development in PDGF-A and PDGFR-α deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis

Karlsson, L., Lindahl, P., Heath, J. K., & Betsholtz, C. (2000) · Development · doi:10.1242/dev.127.16.3457 · Cited by 316

Developmental Control of Blood Cell Migration by the Drosophila VEGF Pathway

Cho, N. K., Keyes, L., Johnson, E., Heller, J., Ryner, L., Karim, F., & Krasnow, M. A. (2002) · Cell · doi:10.1016/s0092-8674(02)00676-1 · Cited by 276

Cell autonomous requirement for PDGFRα in populations of cranial and cardiac neural crest cells

Tallquist, M. D., & Soriano, P. (2003) · Development · doi:10.1242/dev.00241 · Cited by 272

Early myotome specification regulates PDGFA expression and axial skeleton development

Tallquist, M. D., Weismann, K. E., Hellström, M., & Soriano, P. (2000) · Development · doi:10.1242/dev.127.23.5059 · Cited by 260

PDGF Mediates a Neuron–Astrocyte Interaction in the Developing Retina

Fruttiger, M., Calver, A. R., Krüger, W. H., Mudhar, H. S., Michalovich, D., Takakura, N., Nishikawa, S. I., & Richardson, W. D. (1996) · Neuron · doi:10.1016/s0896-6273(00)80244-5 · Cited by 258

A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells

Morrison-Graham, K., Schatteman, G. C., Bork, T., Bowen-Pope, D. F., & Weston, J. A. (1992) · Development · doi:10.1242/dev.115.1.133 · Cited by 256

Leydig Cell Loss and Spermatogenic Arrest in Platelet-Derived Growth Factor (Pdgf)-a–Deficient Mice

Gnessi, L., Basciani, S., Mariani, S., Arizzi, M., Spera, G., Wang, C., Bondjers, C., Karlsson, L., & Betsholtz, C. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.5.1019 · Cited by 244

Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo

Orr-Urtreger, A., & Lonai, P. (1992) · Development · doi:10.1242/dev.115.4.1045 · Cited by 240

Angiogenesis stimulated by PDGF‐CC, a novel member in the PDGF family, involves activation of PDGFR‐aa and ‐ap receptors

Cao, R., Bråkenhielm, E., Li, X., Pietras, K., Widenfalk, J., Östman, A., Eriksson, U., & Cao, Y. (2002) · The FASEB Journal · doi:10.1096/fj.02-0319com · Cited by 229

Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle

Karlsson, L., Bondjers, C., & Betsholtz, C. (1999) · Development · doi:10.1242/dev.126.12.2611 · Cited by 228

Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.

Hermanson, M., Funa, K., Koopmann, J., et al. (1996) · PubMed · Cited by 224

Evidence for Distinct Signaling Properties and Biological Responses Induced by the PDGF Receptor α and β Subtypes

Rosenkranz, S., & Kazlauskas, A. (1999) · Growth Factors · doi:10.3109/08977199909002130 · Cited by 198

An Allelic Series at the PDGFαR Locus Indicates Unequal Contributions of Distinct Signaling Pathways During Development

Klinghoffer, R. A., Hamilton, T. G., Hoch, R., & Soriano, P. (2002) · Developmental Cell · doi:10.1016/s1534-5807(01)00103-4 · Cited by 196

Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling

Heuchel, R., Berg, A., Tallquist, M., Åhlén, K., Reed, R. K., Rubin, K., Claesson-Welsh, L., Heldin, C.-H., & Soriano, P. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11410 · Cited by 188

Divergent Vascular Mechanisms Downstream of Sry Establish the Arterial System in the XY Gonad

Brennan, J., Karl, J., & Capel, B. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0578 · Cited by 186

A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila

Kraut, R., Menon, K., & Zinn, K. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00124-5 · Cited by 183

Invasive cell migration is initiated by guided growth of long cellular extensions

Fulga, T. A., & Rørth, P. (2002) · Nature Cell Biology · doi:10.1038/ncb848 · Cited by 159

PVF1, a PDGF/VEGF homolog, is sufficient to guide border cells and interacts genetically with Taiman

McDonald, J. A., Pinheiro, E. M., & Montell, D. J. (2003) · Development · doi:10.1242/dev.00574 · Cited by 151

The Two PDGF Receptors Maintain Conserved Signaling In Vivo despite Divergent Embryological Functions

Klinghoffer, R. A., Mueting-Nelsen, P. F., Faerman, A., Shani, M., & Soriano, P. M. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00182-4 · Cited by 151

Control of progenitor cell number by mitogen supply and demand

van Heyningen, P., Calver, A. R., & Richardson, W. D. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00075-6 · Cited by 146

PDGFB Regulates the Development of the Labyrinthine Layer of the Mouse Fetal Placenta

OHLSSON, R. I., Falck, P., Hellström, M., Lindahl, P., Boström, H., Franklin, G. C., Ährlund‐Richter, L., Pollard, J. W., Soriano, P. M., & Betsholtz, C. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9306 · Cited by 134

Chromosomal Location, Exon Structure, and Vascular Expression Patterns of the Human PDGFC and PDGFD Genes

Uutela, M., Laurén, J., Bergsten, E., Li, X., Horelli‐Kuitunen, N., Eriksson, U., & Alitalo, K. K. (2001) · Circulation · doi:10.1161/01.cir.103.18.2242 · Cited by 134

Platelet-derived growth factor plays a key role in proliferative vitreoretinopathy.

Andrews, A., Balciunaite, E., Leong, F. L., Tallquist, M. D., Soriano, P. M., Refojo, M. F., & Kazlauskas, A. (1999) · PubMed · Cited by 132

Platelet-Derived Growth Factor A Chain Is Maternally Encoded in Xenopus Embryos

Mercola, M. A., Melton, D. A., & Stiles, C. D. (1988) · Science · doi:10.1126/science.3413486 · Cited by 131

Emphysematous Lesions, Inflammation, and Fibrosis in the Lungs of Transgenic Mice Overexpressing Platelet-Derived Growth Factor

Hoyle, G. W., Li, J., Finkelstein, J. B., Eisenberg, T., Liu, J., Lasky, J. A., Athas, G., Morris, G. F., & Brody, A. R. (1999) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65432-6 · Cited by 131

Intracellular signals and cytoskeletal elements involved in oligodendrocyte progenitor migration

Simpson, P. B., & Armstrong, R. C. (1999) · Glia · Cited by 120

PVF2, a PDGF/VEGF‐like growth factor, induces hemocyte proliferation in Drosophila larvae

Munier, A., Doucet, D., Perrodou, E., Zachary, D., Meister, M. F., Hoffmann, J. A., Janeway, C. A., & Lagueux, M. (2002) · EMBO Reports · doi:10.1093/embo-reports/kvf242 · Cited by 119

The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesis

Ding, H., Wu, X., Kim, I., et al. (2000) · Mechanisms of Development · doi:10.1016/s0925-4773(00)00425-1 · Cited by 118

The Drosophila VEGF receptor homolog is expressed in hemocytes

Heino, T. I., Kärpänen, T., Wahlström, G., Pulkkinen, M., Eriksson, U., Alitalo, K. K., & Roos, C. (2001) · Mechanisms of Development · doi:10.1016/s0925-4773(01)00510-x · Cited by 117

PDGF signalling is required for gastrulation of Xenopus laevis

Ataliotis, P., Symes, K., Chou, M. M., Ho, L., & Mercola, M. A. (1995) · Development · doi:10.1242/dev.121.9.3099 · Cited by 113

Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages

Crosby, J. R., Seifert, R. A., Soriano, P. M., & Bowen‐Pope, D. F. (1998) · Nature Genetics · doi:10.1038/ng0498-385 · Cited by 112

Developmental Expression of Platelet-Derived Growth Factor α-Receptor in Neurons and Glial Cells of the Mouse CNS

Nait‐Oumesmar, B., Vignais, L., & Evercooren, A. B. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00125.1997 · Cited by 110

Walking the Walk

Traver, D. J., & Zon, L. I. (2002) · Cell · doi:10.1016/s0092-8674(02)00686-4 · Cited by 106

Promoter haplotype combinations of the platelet-derived growth factor α-receptor gene predispose to human neural tube defects

Joosten, P. H. L. J., Toepoel, M., Mariman, E. C. M., & van Zoelen, E. J. J. (2001) · Nature Genetics · doi:10.1038/84867 · Cited by 103

Two closely linked genes in the mouse

Grüneberg, H., & Truslove, G. M. (1960) · Genetics Research · doi:10.1017/s0016672300000094 · Cited by 100

Involvement of Platelet-Derived Growth Factor Receptor-α in Hair Canal Formation

Takakura, N., Yoshida, H., Kunisada, T., Nishikawa, S., & Nishikawa, S.-I. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12371802 · Cited by 88

Diminished Matrix Metalloproteinase 2 (MMP-2) in Ectomesenchyme-Derived Tissues of the Patch Mutant Mouse: Regulation of MMP-2 by PDGF and Effects on Mesenchymal Cell Migration

Robbins, J. R., McGuire, P. G., Wehrle‐Haller, B., & Rogers, S. L. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9373 · Cited by 81

Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice

Kaminski, W. E., Lindahl, P., Lin, N. L., Broudy, V. C., Crosby, J. R., Hellström, M., Swolin, B., Bowen-Pope, D. F., Martin, P. J., Ross, R., et al. (2001) · Blood · doi:10.1182/blood.v97.7.1990 · Cited by 77

PDGF-C Expression in the Developing and Normal Adult Human Kidney and in Glomerular Diseases

Eitner, F., Ostendorf, T., Kretzler, M., Cohen, C. D., Eriksson, U., Gröne, H., & Floege, J. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000062964.75006.a8 · Cited by 75

Interaction between undulated and Patch leads to an extreme form of spina bifida in double-mutant mice

Helwig, U., Imai, K., Schmahl, W., Thomas, B., Varnum, D. S., Nadeau, J. H., & Balling, R. (1995) · Nature Genetics · doi:10.1038/ng0995-60 · Cited by 74

A human YAC transgene rescues craniofacial and neural tube development inPDGFRα knockout mice and uncovers a role for PDGFRα in prenatal lung growth

Sun, T., Jayatilake, D., Afink, G., Ataliotis, P., Nistér, M., Richardson, W. D., & Smith, H. K. (2000) · Development · doi:10.1242/dev.127.21.4519 · Cited by 71

Expression analysis of PDGF-C in adult and developing mouse tissues

Aase, K., Abramsson, A., Karlsson, L., Betsholtz, C., & Eriksson, U. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(01)00560-3 · Cited by 65

Chronic allograft nephropathy is prevented by inhibition of platelet-derived growth factor receptor: tyrosine kinase inhibitors as a potential therapy

Savikko, J., Taskinen, E., & von Willebrand, E. (2003) · Transplantation · doi:10.1097/01.tp.0000062836.93496.ce · Cited by 65

Caenorhabditis elegans receptors related to mammalian vascular endothelial growth factor receptors are expressed in neural cells

Popovici, C., Isnardon, D., Birnbaum, D., & Roubin, R. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00595-5 · Cited by 59

An in vivo gene therapy approach for experimental proliferative vitreoretinopathy using the truncated platelet-derived growth factor alpha receptor.

Ikuno, Y., & Kazlauskas, A. (2002) · PubMed · Cited by 58

Over-expression of platelet-derived growth factor in human diabetic nephropathy

Langham, R. G., Kelly, D. J., Maguire, J. A., et al. (2003) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfg177 · Cited by 57

Overexpression of PDGF-A in the Lung Epithelium of Transgenic Mice Produces a Lethal Phenotype Associated with Hyperplasia of Mesenchymal Cells

Li, J., & Hoyle, G. W. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0441 · Cited by 56

Embryonic mesoderm cells spread in response to platelet-derived growth factor and signaling by phosphatidylinositol 3-kinase.

Symes, K., & Mercola, M. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9641 · Cited by 52

Localization of PDGF A and PDGFRα mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells

Ho, L., Symes, K., Yordán, C., et al. (1994) · Mechanisms of Development · doi:10.1016/0925-4773(94)90057-4 · Cited by 50

Complement components C1r/C1s, bone morphogenic protein 1 and Xenopus laevis developmentally regulated protein UVS.2 share common repeats

Bork, P. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)80433-4 · Cited by 49

Spina bifida occulta in homozygous Patch mouse embryos

Payne, J., Shibasaki, F., & Mercola, M. A. (1997) · Developmental Dynamics · Cited by 44

The Family of Caenorhabditis elegans Tyrosine Kinase Receptors: Similarities and Differences with Mammalian ReceptorsPreprint

Popovici, C., Roubin, R., Coulier, F., Pontarotti, P., & Birnbaum, D. (1999) · Genome Research · doi:10.1101/gr.9.11.1026 · Cited by 44

Platelet-derived growth factor A modulates limb chondrogenesis both in vivo and in vitro

Ataliotis, P. (2000) · Mechanisms of Development · doi:10.1016/s0925-4773(00)00321-x · Cited by 43

Retinoic Acid Inhibits Cardiac Neural Crest Migration by Blocking c-Jun N-Terminal Kinase Activation

Li, J., Molkentin, J. D., & Colbert, M. C. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0203 · Cited by 40

Neuron-Specific Ablation of PDGF-B Is Compatible with Normal Central Nervous System Development and Astroglial Response to Injury

Enge, M., Wilhelmsson, U., Abramsson, A., Stakeberg, J., Kühn, R., Betsholtz, C., & Pekny, M. (2003) · Neurochemical Research · doi:10.1023/a:1022421001288 · Cited by 39

Platelet-derived growth factor effects on purified testicular peritubular myoid cells: binding, cytosolic Ca2+ increase, mitogenic activity, and extracellular matrix production enhancement

Gnessi, L., Emidi, A., Scarpa, S., Palleschi, S., Ragano‐Caracciolo, M., Silvestroni, L., Modesti, A., & Spera, G. (1993) · Endocrinology · doi:10.1210/en.133.4.1880 · Cited by 37

PDGF-α receptor is expressed by mature neurones of the central nervous system

Vignais, L., Nait‐Oumesmar, B., & Evercooren, A. B. (1995) · Neuroreport · doi:10.1097/00001756-199510010-00010 · Cited by 35

Platelet-derived Growth Factor Receptor β Regulates Migration and DNA Synthesis in Metanephric Mesenchymal Cells

Arar, M. Y., Xu-Dubois, Y.-C., Elshihabi, I., Barnes, J. L., Choudhury, G. G., & Abboud, H. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9527 · Cited by 33

Platelet-derived growth factor receptor alpha (pdgfr-α) gene in zebrafish embryonic development

Liu, L., Chong, S., Balasubramaniyan, N. V., Korzh, V. P., & Ge, R. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(02)00142-9 · Cited by 30

Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF‐B in myelinating tracts

Forsberg‐Nilsson, K., Erlandsson, A., Zhang, X., Ueda, H., Svensson, K., Nistér, M., Trapp, B. D., Peterson, A. C., & Westermark, B. (2003) · Glia · doi:10.1002/glia.10191 · Cited by 22

Quality Control of Receptor-Kinase Signaling Complexes

Bonifacino, J. S. (2002) · Developmental Cell · doi:10.1016/s1534-5807(01)00114-9 · Cited by 14

Identification of new signaling components in the Drosophila genome sequence

Pietrokovski, S., & Shilo, B. (2001) · Functional & Integrative Genomics · doi:10.1007/s101420000023 · Cited by 9

Endothelial/Pericyte Interactions

Armulik, A., Abramsson, A., & Betsholtz, C. (2005) · Circulation Research · doi:10.1161/01.res.0000182903.16652.d7 · Cited by 2,048

The brain tumor microenvironment

Charles, N. A., Holland, E. C., Gilbertson, R., Glass, R., & Kettenmann, H. (2011) · Glia · doi:10.1002/glia.21136 · Cited by 718

Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst

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