Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625 · see citing works

limma powers differential expression analyses for RNA-sequencing and microarray studies

Ritchie, M. E., Phipson, B., Wu, D., Hu, Y., Law, C. W., Shi, W., & Smyth, G. K. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv007 · Cited by 40,458 · see citing works

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009) · Science · doi:10.1126/science.1160809 · Cited by 16,197 · see citing works

ggplot2: Elegant Graphics for Data Analysis

Wickham, H. (2009) · doi:10.1007/978-0-387-98141-3 · Cited by 14,447 · see citing works

The Molecular Signatures Database Hallmark Gene Set Collection

Liberzon, A., Birger, C., Thorvaldsdóttir, H., Ghandi, M., Mesirov, J. P., & Tamayo, P. (2015) · Cell Systems · doi:10.1016/j.cels.2015.12.004 · Cited by 13,807 · see citing works

Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients

Locatelli, F., Fishbane, S. N., Block, G. A., & Macdougall, I. C. (2017) · American Journal of Nephrology · doi:10.1159/000455166 · Cited by 4,834 · see citing works

On Respiratory Impairment in Cancer Cells

Warburg, O. H. (1956) · Science · doi:10.1126/science.124.3215.269 · Cited by 3,472 · see citing works

Pax7 Is Required for the Specification of Myogenic Satellite Cells

Seale, P., Sabourin, L. A., Girgis-Gabardo, A., Mansouri, A., Gruß, P., & Rudnicki, M. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00066-0 · Cited by 2,345 · see citing works

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

Joe, A. W. B., Yi, L., Natarajan, A., Le Grand, F., So, L., Wang, J., Rudnicki, M. A., & Rossi, F. M. V. (2010) · Nature Cell Biology · doi:10.1038/ncb2015 · Cited by 1,690 · see citing works

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

Khatri, P., Sirota, M., & Butte, A. J. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002375 · Cited by 1,569 · see citing works

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

Gomes, A. P., Price, N. L., Ling, A. J. Y., Moslehi, J. J., Montgomery, M. K., Rajman, L., White, J. P., Teodoro, J. S., Wrann, C. D., Hubbard, B. P., et al. (2013) · Cell · doi:10.1016/j.cell.2013.11.037 · Cited by 1,482 · see citing works

Autophagy maintains stemness by preventing senescence

García-Prat, L., Martínez-Vicente, M., Perdiguero, E., Ortet, L., Rodríguez-Ubreva, J., Rebollo, E., Ruiz-Bonilla, V., Gutarra, S., Ballestar, E., Serrano, A. L., et al. (2016) · Nature · doi:10.1038/nature16187 · Cited by 1,355 · see citing works

ggplot2: Elegant Graphics for Data Analysis (2nd ed.)

Villanueva, R. A. M., & Chen, Z. J. (2019) · Measurement Interdisciplinary Research and Perspectives · doi:10.1080/15366367.2019.1565254 · Cited by 1,323 · see citing works

Cancer metabolism: fatty acid oxidation in the limelight

Carracedo, A., Cantley, L. C., & Pandolfi, P. P. (2013) · Nature reviews. Cancer · doi:10.1038/nrc3483 · Cited by 1,316 · see citing works

NAD ⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

Zhang, H., Ryu, D., Wu, Y., Gariani, K., Wang, X., Luan, P., D’Amico, D., Ropelle, E. R., Lutolf, M. P., Aebersold, R., et al. (2016) · Science · doi:10.1126/science.aaf2693 · Cited by 1,255 · see citing works

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

Murphy, M. M., Lawson, J. A., Mathew, S. J., Hutcheson, D. A., & Kardon, G. (2011) · Development · doi:10.1242/dev.064162 · Cited by 1,249 · see citing works

Arteriolar niches maintain haematopoietic stem cell quiescence

Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J. U., Pinho, S., Zhang, D., Mizoguchi, T., Wei, Q., Lucas, D., Ito, K., et al. (2013) · Nature · doi:10.1038/nature12612 · Cited by 1,236 · see citing works

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

Lepper, C., Partridge, T. A., & Fan, C.-M. (2011) · Development · doi:10.1242/dev.067595 · Cited by 1,105 · see citing works

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

Simsek, T., Kocabas, F., Zheng, J., DeBerardinis, R. J., Mahmoud, A. I., Olson, E. N., Schneider, J. W., Zhang, C. C., & Sadek, H. A. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.07.011 · Cited by 1,101 · see citing works

Metabolic requirements for the maintenance of self-renewing stem cells

Ito, K., & Suda, T. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3772 · Cited by 1,014 · see citing works

Geriatric muscle stem cells switch reversible quiescence into senescence

Sousa-Victor, P., Gutarra, S., García-Prat, L., Rodriguez-Ubreva, J., Ortet, L., Ruiz-Bonilla, V., Jardí, M., Ballestar, E., González, S., Serrano, A. L., et al. (2014) · Nature · doi:10.1038/nature13013 · Cited by 1,010 · see citing works

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

Folmes, C. D. L., Nelson, T. J., Martinez‐Fernandez, A., Arrell, D. K., Lindor, J. Z., Dzeja, P. P., Ikeda, Y., Pérez-Terzic, C. M., & Terzic, A. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.06.011 · Cited by 980 · see citing works

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

Sambasivan, R., Yao, R., Kissenpfennig, A., Van Wittenberghe, L., Paldi, A., Gayraud-Morel, B., Guenou, H., Malissen, B., Tajbakhsh, S., & Galy, A. (2011) · Development · doi:10.1242/dev.067587 · Cited by 939 · see citing works

Hematopoietic stem cell: self‐renewal versus differentiation

Seita, J., & Weissman, I. L. (2010) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.86 · Cited by 925 · see citing works

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

Wu, M., Neilson, A., Swift, A. L., Moran, R., Tamagnine, J., Parslow, D., Armistead, S., Lemire, K., Orrell, J., Teich, J., et al. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00247.2006 · Cited by 922 · see citing works

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

Takubo, K., Goda, N., Yamada, W., Iriuchishima, H., Ikeda, E., Kubota, Y., Shima, H., Johnson, R. S., Hirao, A., Suematsu, M., et al. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.06.020 · Cited by 891 · see citing works

Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

Parmar, K., Mauch, P., Vergilio, J.-A., Sackstein, R., & Down, J. D. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701152104 · Cited by 867 · see citing works

The aged niche disrupts muscle stem cell quiescence

Chakkalakal, J. V., Jones, K. M., Basson, M. A., & Brack, A. S. (2012) · Nature · doi:10.1038/nature11438 · Cited by 851 · see citing works

Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models

Schiaffino, S., & Mammucari, C. (2011) · Skeletal Muscle · doi:10.1186/2044-5040-1-4 · Cited by 816 · cited 1× · see citing works

Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

Takubo, K., Nagamatsu, G., Kobayashi, C. I., Nakamura‐Ishizu, A., Kobayashi, H., Ikeda, E., Goda, N., Rahimi, Y., Johnson, R. S., Soga, T., et al. (2013) · Cell stem cell · doi:10.1016/j.stem.2012.10.011 · Cited by 810 · see citing works

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

Rodgers, J. T., King, K. Y., Brett, J. O., Cromie, M. J., Charville, G. W., Maguire, K. K., Brunson, C., Mastey, N., Liu, L., Tsai, C.-R., et al. (2014) · Nature · doi:10.1038/nature13255 · Cited by 776 · see citing works

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells

Relaix, F., Montarras, D., Zaffran, S., Gayraud-Morel, B., Rocancourt, D., Tajbakhsh, S., Mansouri, A., Cumano, A., & BUCKINGHAM, M. E. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200508044 · Cited by 736 · see citing works

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

Ito, K., Carracedo, A., Weiss, D., Arai, F., Ala, U., Avigan, D., Schafer, Z. T., Evans, R. M., Suda, T., Lee, C., et al. (2012) · Nature Medicine · doi:10.1038/nm.2882 · Cited by 731 · see citing works

Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells

Chen, C.-T., Shih, Y.-R. V., Kuo, T. K., Lee, O. K., & Wei, Y. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0509 · Cited by 709 · see citing works

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

Väremo, L., Nielsen, J., & Nookaew, I. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt111 · Cited by 683 · see citing works

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

Chen, C., Liu, Y., Liu, R., Ikenoue, T., Guan, K.-L., Liu, Y., & Zheng, P. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20081297 · Cited by 682 · see citing works

Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts

Varum, S., Rodrigues, A. S., Moura, M. B., Momcilovic, O., Easley, C. A., Ramalho-Santos, J., Van Houten, B., & Schatten, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020914 · Cited by 671 · see citing works

Pax7 is critical for the normal function of satellite cells in adult skeletal muscle

von Maltzahn, J., Jones, A. E., Parks, R. J., & Rudnicki, M. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307680110 · Cited by 602 · see citing works

Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements

Lepper, C., Conway, S. J., & Fan, C. (2009) · Nature · doi:10.1038/nature08209 · Cited by 580 · see citing works

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

Ryall, J. G., Dell’Orso, S., Derfoul, A., Juan, A., Zare, H., Feng, X., Clermont, D., Koulnis, M., Gutierrez-Cruz, G., Fulco, M., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2014.12.004 · Cited by 575 · see citing works

Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging

Liu, L., Cheung, T. H., Charville, G. W., Hurgo, B. M. C., Leavitt, T., Shih, J., Brunet, A., & Rando, T. A. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.05.043 · Cited by 544 · see citing works

A Subpopulation of Adult Skeletal Muscle Stem Cells Retains All Template DNA Strands after Cell Division

Rocheteau, P., Gayraud-Morel, B., Siegl-Cachedenier, I., Blasco, M. A., & Tajbakhsh, S. (2012) · Cell · doi:10.1016/j.cell.2011.11.049 · Cited by 510 · see citing works

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

Zhang, J., Khvorostov, I., Hong, J. S., Oktay, Y., Vergnes, L., Nuebel, E., Wahjudi, P. N., Setoguchi, K., Wang, G., Do, A., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.401 · Cited by 499 · see citing works

Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells

Cho, Y. M., Kwon, S., Pak, Y. K., Seol, H. W., Choi, Y. M., Park, D. J., Park, K. S., & Lee, H. K. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.08.020 · Cited by 465 · see citing works

Advances in measuring cellular bioenergetics using extracellular flux

Ferrick, D. A., Neilson, A., & Beeson, C. C. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2007.12.008 · Cited by 455 · see citing works

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

Gan, B., HU, J. L., Jiang, S., Liu, Y., Sahin, E., Li, Z., Fletcher-Sananikone, E., Colla, S., Wang, Y., Chin, L., et al. (2010) · Nature · doi:10.1038/nature09595 · Cited by 437 · see citing works

Distinct Regulatory Cascades Govern Extraocular and Pharyngeal Arch Muscle Progenitor Cell Fates

Sambasivan, R., Gayraud-Morel, B., Dumas, G., Cimper, C., Paisant, S., Kelly, R. G., & Tajbakhsh, S. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.05.008 · Cited by 400 · see citing works

Cellular dynamics in the muscle satellite cell niche

Bentzinger, C. F., Wang, Y. X., Dumont, N. A., & Rudnicki, M. A. (2013) · The EMBO Reports · doi:10.1038/embor.2013.182 · Cited by 398 · see citing works

Short-Term Calorie Restriction Enhances Skeletal Muscle Stem Cell Function

Cerletti, M., Jang, Y. C., Finley, L. W. S., Haigis, M. C., & Wagers, A. J. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.04.002 · Cited by 397 · see citing works

New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle

Stephens, F. B., Constantin‐Teodosiu, D., & Greenhaff, P. L. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2006.125799 · Cited by 396 · see citing works

The Peroxisome-Mitochondria Connection: How and Why?

Fransen, M., Lismont, C., & Walton, P. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061126 · Cited by 351 · see citing works

Skeletal muscle stem cells in developmental versus regenerative myogenesis

Tajbakhsh, S. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02158.x · Cited by 333 · see citing works

A High Glycolytic Flux Supports the Proliferative Potential of Murine Embryonic Stem Cells

Kondoh, H., Lleonart, M. E., Nakashima, Y., Yokode, M., Tanaka, M., Bernard, D., Gil, J., & Beach, D. (2007) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.1467 · Cited by 325 · see citing works

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

Naito, A. T., Sumida, T., Nomura, S., Liu, M.-L., Higo, T., Nakagawa, A., Okada, K., Sakai, T., Hashimoto, A., Hara, Y., et al. (2012) · Cell · doi:10.1016/j.cell.2012.03.047 · Cited by 320 · see citing works

The metabolic programming of stem cellsPreprint

Shyh‐Chang, N., & Ng, H. (2017) · Genes & Development · doi:10.1101/gad.293167.116 · Cited by 317 · see citing works

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

Tang, A. H., & Rando, T. A. (2014) · The EMBO Journal · doi:10.15252/embj.201488278 · Cited by 294 · see citing works

The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?

Wessel, T. V., HAAN, A. D., van der Laarse, W. J., & Jaspers, R. T. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1545-0 · Cited by 286 · see citing works

Myf5-Positive Satellite Cells Contribute to Pax7-Dependent Long-Term Maintenance of Adult Muscle Stem Cells

Günther, S., Kim, J., Kostin, S., Lepper, C., Fan, C.-M., & Braun, T. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.07.016 · Cited by 280 · see citing works

Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State

Gu, W., Gaeta, X., Sahakyan, A., Chan, A. B., Hong, C. S., Kim, R., Braas, D., Plath, K., Lowry, W. E., & Christofk, H. R. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.08.008 · Cited by 275 · see citing works

A role for the myogenic determination gene Myf5 in adult regenerative myogenesis

Gayraud-Morel, B., Chrétien, F. C., Flamant, P., Gomès, D., Zammit, P. S., & Tajbakhsh, S. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.08.059 · Cited by 240 · see citing works

Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress

Solanas, G., Peixoto, F. O., Perdiguero, E., Jardı́, M., Ruiz‐Bonilla, V., Datta, D., Symeonidi, A., Castellanos‐Martín, A., Welz, P.-S., Caballero, J. M., et al. (2017) · Cell · doi:10.1016/j.cell.2017.07.035 · Cited by 229 · see citing works

Skeletal muscle mitochondria: A major player in exercise, health and disease

Russell, A. P., Foletta, V. C., Snow, R. J., & Wadley, G. D. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.11.016 · Cited by 223 · see citing works

Molecular and Cellular Regulation of Skeletal Myogenesis

Comai, G., & Tajbakhsh, S. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-405943-6.00001-4 · Cited by 205 · see citing works

Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress

Filosa, S., Fico, A., Paglialunga, F., Balestrieri, M., Crooke, A., Verde, P., Abrescia, P., Bautista, J. M., & Martini, G. (2003) · Biochemical Journal · doi:10.1042/bj20021614 · Cited by 181 · see citing works

Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity

Latil, M., Rocheteau, P., Châtre, L., Sanulli, S., Mémet, S., Ricchetti, M., Tajbakhsh, S., & Chrétien, F. (2012) · Nature Communications · doi:10.1038/ncomms1890 · Cited by 165 · see citing works

Impaired Mitochondrial Dynamics and Bioenergetics in Diabetic Skeletal Muscle

Liu, R., Jin, P., LiqunYu, Wang, Y., Han, L., Shi, T., & Li, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092810 · Cited by 146 · see citing works

Skeletal muscle stem cell birth and properties

Sambasivan, R., & Tajbakhsh, S. (2007) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2007.09.013 · Cited by 143 · see citing works

Protection from oxidative stress by enhanced glycolysis; a possible mechanism of cellular immortalization.

Kondoh, H., LLeonart, M. E., Bernard, D., & Gil, J. (2007) · PubMed · doi:10.14670/hh-22.85 · Cited by 142 · see citing works

Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells

Prigione, A., & Adjaye, J. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.103198ap · Cited by 135 · see citing works

Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK

Merry, T. L., Steinberg, G. R., Lynch, G. S., & McConell, G. K. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00239.2009 · Cited by 122 · see citing works

Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal

Yousef, H., Conboy, M. J., Morgenthaler, A., Schlesinger, C., Bugaj, L. J., Paliwal, P., Greer, C. D., Conboy, I. M., & Schaffer, D. V. (2015) · Oncotarget · doi:10.18632/oncotarget.3851 · Cited by 115 · see citing works

Cancer Usurps Skeletal Muscle as an Energy Repository

Luo, Y., Yoneda, J., Ohmori, H., Sasaki, T., Shimbo, K., Eto, S., KATO, Y. O., Miyano, H., Kobayashi, T., Sasahira, T., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-13-1052 · Cited by 112 · see citing works

Measurement of metabolites in single preimplantation embryos; a new means to study metabolic control in early embryos

Barbehenn, E. K., Wales, R. G., & Lowry, O. H. (1978) · Development · doi:10.1242/dev.43.1.29 · Cited by 112 · see citing works

Coupling organelle inheritance with mitosis to balance growth and differentiation

Asare, A., Levorse, J. M., & Fuchs, E. V. (2017) · Science · doi:10.1126/science.aah4701 · Cited by 94 · see citing works

Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells

Gayraud-Morel, B., Chrétien, F. C., Jory, A., Sambasivan, R., Négroni, E., Flamant, P., Soubigou, G., Coppée, J., Santo, J. P. D., Cumano, A., et al. (2012) · Journal of Cell Science · doi:10.1242/jcs.097006 · Cited by 92 · see citing works

Cell Adhesion Geometry Regulates Non-Random DNA Segregation and Asymmetric Cell Fates in Mouse Skeletal Muscle Stem Cells

Yennek, S., Burute, M., Théry, M., & Tajbakhsh, S. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.04.016 · Cited by 81 · see citing works

More efficient repair of DNA double-strand breaks in skeletal muscle stem cells compared to their committed progeny

Ferdousi, L. V., Rocheteau, P., Chayot, R., Montagne, B., Chaker, Z., Flamant, P., Tajbakhsh, S., & Ricchetti, M. (2014) · Stem Cell Research · doi:10.1016/j.scr.2014.08.005 · Cited by 77 · see citing works

A metabolic link to skeletal muscle wasting and regeneration

Koopman, R., Ly, C. H., & Ryall, J. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00032 · Cited by 77 · see citing works

Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments

Karunadharma, P. P., Basisty, N., Chiao, Y. A., Dai, D., Drake, R., Levy, N., Koh, W. J. H., Emond, M. J., Kruse, S. E., Marcinek, D. J., et al. (2015) · The FASEB Journal · doi:10.1096/fj.15-272666 · Cited by 69 · see citing works

Functional and phenotypic characteristics of CD4+CD25highFoxp3+ Treg clones obtained from peripheral blood of patients with cancer

Strauss, L., Bergmann, C., & Whiteside, T. L. (2007) · International Journal of Cancer · doi:10.1002/ijc.23001 · Cited by 63 · see citing works

Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis

Alonso‐Martín, S., Rochat, A., Mademtzoglou, D., Morais, J., de Reyniès, A., Aurade, F., Chang, T. H., Zammit, P. S., & Relaix, F. (2016) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2016.00058 · Cited by 61 · see citing works

Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4

Sambasivan, R., Comai, G., Roux, I. L., Gomès, D., Konge, J. C., Dumas, G., Cimper, C., & Tajbakhsh, S. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.04.018 · Cited by 58 · see citing works

Energy Metabolism in Nuclear Reprogramming

Folmes, C. D. L., Nelson, T. J., & Terzic, A. (2011) · Biomarkers in Medicine · doi:10.2217/bmm.11.87 · Cited by 56 · see citing works

Thioridazine: a selective inhibitor of peroxisomal β‐oxidation in vivo

Branden, C. V. D., & Roels, F. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)81270-9 · Cited by 48 · see citing works

Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells

Pietrosemoli, N., Mella, S., Yennek, S., Baghdadi, M. B., Sakai, H., Sambasivan, R., Pala, F., Girolamo, D. D., & Tajbakhsh, S. (2017) · Skeletal Muscle · doi:10.1186/s13395-017-0144-8 · Cited by 41 · see citing works

Stereospecificity of the inhibition by etomoxir of fatty acid and cholesterol synthesis in isolated rat hepatocytes

Agius, L., Meredith, E. J., & Sherratt, H. S. A. (1991) · Biochemical Pharmacology · doi:10.1016/0006-2952(91)90507-2 · Cited by 33 · see citing works

The role of sirtuins in the regulation of metabolic homeostasis in skeletal muscle

Ryall, J. G. (2012) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e3283590914 · Cited by 25 · see citing works

Isolation of Muscle Stem Cells from Mouse Skeletal Muscle

Gayraud-Morel, B., Pala, F., Sakai, H., & Tajbakhsh, S. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6771-1_2 · Cited by 24 · see citing works

Hypoxia and Visualization of the Stem Cell Niche

Dalloul, A. H. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-508-8_17 · Cited by 22 · see citing works

Simultaneous Measurement of Mitochondrial and Glycolytic Activity in Quiescent Muscle Stem Cells

Ryall, J. G. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6771-1_13 · Cited by 19 · see citing works

Hypoxia Induces a Metabolic Shift and Enhances the Stemness and Expansion of Cochlear Spiral Ganglion Stem/Progenitor Cells

Chen, H., Lee, J.-T., Shih, C., Chao, T., Sytwu, H., Li, S.-L., Fang, M.-C., Chen, H.-K., Lin, Y., Kuo, C.-Y., et al. (2015) · BioMed Research International · doi:10.1155/2015/359537 · Cited by 17 · see citing works

Control of satellite cell function in muscle regeneration and its disruption in ageing

Sousa-Victor, P., García-Prat, L., & Muñoz-Cánoves, P. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-021-00421-2 · Cited by 476 · see citing works

Ageing and rejuvenation of tissue stem cells and their niches

Brunet, A., Goodell, M. A., & Rando, T. A. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00510-w · Cited by 407 · see citing works

Perspectives on skeletal muscle stem cells

Relaix, F., Bencze, M., Borok, M. J., Vartanian, A. D., Gattazzo, F., Mademtzoglou, D., Perez-Diaz, S., Prola, A., Fernandez, P. C. R., Rotini, A., et al. (2021) · Nature Communications · doi:10.1038/s41467-020-20760-6 · Cited by 389 · see citing works

Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions

Dell'Orso, S., Juan, A. H., Ko, K.-D., Naz, F., Perovanovic, J., Gutierrez-Cruz, G., Feng, X., & Sartorelli, V. (2019) · Development · doi:10.1242/dev.174177 · Cited by 243 · see citing works

Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy

Hong, X., Isern, J., Campanario, S., Perdiguero, E., Ramírez-Pardo, I., Segalés, J., Hernansanz-Agustín, P., Curtabbi, A., Deryagin, O., Pollán, A., et al. (2022) · Cell stem cell · doi:10.1016/j.stem.2022.07.009 · Cited by 213 · see citing works

A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells

Xi, H., Langerman, J., Sabri, S., Chien, P., Young, C. S., Younesi, S., Hicks, M. R., Gonzalez, K. M., Fujiwara, W., Marzi, J., et al. (2020) · Cell stem cell · doi:10.1016/j.stem.2020.04.017 · Cited by 156 · see citing works

Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

Yucel, N., Wang, Y. X., Mai, T., Porpiglia, E., Lund, P. J., Markov, G., Garcia, B. A., Bendall, S. C., Angelo, M., & Blau, H. M. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.092 · Cited by 159 · see citing works

Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Farup, J., Just, J., de Paoli, F. V., Lin, L., Jensen, J., Billeskov, T. B., Sánchez-Román, I., Cömert, C., Møller, A. B., Madaro, L., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.10.001 · Cited by 154 · see citing works

Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

Sahu, A., Clemens, Z. J., Shinde, S. N., Sivakumar, S., Pius, A., Bhatia, A., Picciolini, S., Carlomagno, C., Gualerzi, A., Bedoni, M., et al. (2021) · Nature Aging · doi:10.1038/s43587-021-00143-2 · Cited by 145 · see citing works

Functionally heterogeneous human satellite cells identified by single cell RNA sequencing

Barruet, E., Garcia, S. M., Striedinger, K., Wu, J., Lee, S., Byrnes, L. E., Wong, A., Sun, X., Tamaki, S. J., Brack, A. S., et al. (2020) · eLife · doi:10.7554/elife.51576 · Cited by 142 · see citing works

A Metabolic Roadmap for Somatic Stem Cell Fate

Ly, C., Lynch, G. S., & Ryall, J. G. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.04.022 · Cited by 139 · see citing works

Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease

Giuliani, G., Rosina, M., & Reggio, A. (2021) · FEBS Journal · doi:10.1111/febs.16080 · Cited by 138 · see citing works

Skeletal muscle stem cells in comfort and stress

Evano, B., & Tajbakhsh, S. (2018) · npj Regenerative Medicine · doi:10.1038/s41536-018-0062-3 · Cited by 132 · see citing works

Satellite cells in ageing: use it or lose it

Chen, W. C., Datzkiw, D., & Rudnicki, M. A. (2020) · Open Biology · doi:10.1098/rsob.200048 · Cited by 116 · see citing works

The emergence of the stem cell niche

Hicks, M. R., & Pyle, A. D. (2022) · Trends in Cell Biology · doi:10.1016/j.tcb.2022.07.003 · Cited by 112 · see citing works

Quiescence: Good and Bad of Stem Cell Aging

Tümpel, S., & Rudolph, K. L. (2019) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.05.002 · Cited by 108 · see citing works

Distinct Phases of Postnatal Skeletal Muscle Growth Govern the Progressive Establishment of Muscle Stem Cell Quiescence

Gattazzo, F., Laurent, B., Relaix, F., Rouard, H., & Didier, N. (2020) · Stem Cell Reports · doi:10.1016/j.stemcr.2020.07.011 · Cited by 93 · see citing works

Mitochondrial Dysfunction as an Underlying Cause of Skeletal Muscle Disorders

Chen, T., Koh, K.-Y., Lin, K. M.-C., & Chou, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112926 · Cited by 93 · see citing works

Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice

Sincennes, M., Brun, C. E., Lin, A. Y., Rosembert, T., Datzkiw, D., Saber, J., Hong, M., Kawabe, Y.-I., & Rudnicki, M. A. (2021) · Nature Communications · doi:10.1038/s41467-021-23577-z · Cited by 88 · see citing works

Mitochondrial Function in Muscle Stem Cell Fates

Bhattacharya, D., & Scimè, A. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00480 · Cited by 88 · see citing works

The role of SIRT1 in skeletal muscle function and repair of older mice

Myers, M. J., Shepherd, D. L., Durr, A. J., Stanton, D. S., Mohamed, J. S., Hollander, J. M., & Alway, S. E. (2019) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12437 · Cited by 86 · see citing works

The paradox of metabolism in quiescent stem cells

Coller, H. A. (2019) · FEBS Letters · doi:10.1002/1873-3468.13608 · Cited by 82 · see citing works

Muscle Stem Cell Quiescence: Controlling Stemness by Staying Asleep

Ancel, S., Stuelsatz, P., & Feige, J. N. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.02.006 · Cited by 76 · see citing works

Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis

Shcherbina, A., Larouche, J., Fraczek, P., Yang, B. A., Brown, L. A., Markworth, J. F., Chung, C. H., Khaliq, M., de Silva, K., Choi, J. J., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107964 · Cited by 76 · see citing works

Lipid droplet dynamics regulate adult muscle stem cell fate

Yue, F., Oprescu, S. N., Qiu, J., Gu, L., Zhang, L., Chen, J., Narayanan, N., Deng, M., & Kuang, S. (2022) · Cell Reports · doi:10.1016/j.celrep.2021.110267 · Cited by 78 · see citing works

Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging

Benjamin, D. I., Brett, J. O., Both, P., Benjamin, J. S., Ishak, H. D., Kang, J., Kim, S., Chung, M., Arjona, M., Nutter, C. W., et al. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.02.001 · Cited by 79 · see citing works

Mitochondrial Dysfunction in Cancer Cachexia: Impact on Muscle Health and Regeneration

Beltrà, M., Pin, F., Ballarò, R., Costelli, P., & Penna, F. (2021) · Cells · doi:10.3390/cells10113150 · Cited by 76 · see citing works

CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells

Ruetz, T. J., Pogson, A. N., Kashiwagi, C. M., Gagnon, S. D., Morton, B., Sun, E., Na, J., Yeo, R. W., Leeman, D. S., Morgens, D. W., et al. (2024) · Nature · doi:10.1038/s41586-024-07972-2 · Cited by 71 · see citing works

Stem cell aging in the skeletal muscle: The importance of communication

Hong, X., Campanario, S., Ramírez‐Pardo, I., Grima-Terrén, M., Isern, J., & Muñoz‐Cánoves, P. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101528 · Cited by 69 · see citing works

Interplay between mitochondrial reactive oxygen species, oxidative stress and hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target

Heher, P., Ganassi, M., Weidinger, A., Engquist, E. N., Prüller, J., Nguyen, T. H., Tassin, A., Declèves, A., Mamchaoui, K., Banerji, C. R. S., et al. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102251 · Cited by 65 · see citing works

Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration

Reggio, A., Rosina, M., Krahmer, N., Palma, A., Petrilli, L. L., Maiolatesi, G., Massacci, G., Salvatori, I., Valle, C., Testa, S., et al. (2020) · Life Science Alliance · doi:10.26508/lsa.202000660 · Cited by 62 · see citing works

Metabolomic analysis of primary human skeletal muscle cells during myogenic progression

Kumar, A., Kumar, Y., Sevak, J. K., Kumar, S., Kumar, N., & Gopinath, S. D. (2020) · Scientific Reports · doi:10.1038/s41598-020-68796-4 · Cited by 66 · see citing works

Autophagy as a Therapeutic Target to Enhance Aged Muscle Regeneration

Lee, D. E., Bareja, A., Bartlett, D. B., & White, J. P. (2019) · Cells · doi:10.3390/cells8020183 · Cited by 64 · see citing works

A cross-talk between sestrins, chronic inflammation and cellular senescence governs the development of age-associated sarcopenia and obesity

Livshits, G., & Kalinkovich, A. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101852 · Cited by 55 · see citing works

The Microenvironment Is a Critical Regulator of Muscle Stem Cell Activation and Proliferation

Nguyen, J. H. V., Chung, J. D., Lynch, G. S., & Ryall, J. G. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00254 · Cited by 52 · see citing works

Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance

Harvey, A. J., Caretti, G., Moresi, V., Renzini, A., & Adamo, S. (2019) · Stem Cell Reports · doi:10.1016/j.stemcr.2019.09.003 · Cited by 51 · see citing works

The Multiple Roles of Lactate in the Skeletal Muscle

Bartoloni, B., Mannelli, M., Gamberi, T., & Fiaschi, T. (2024) · Cells · doi:10.3390/cells13141177 · Cited by 51 · see citing works

Metabolic Regulation of Stem Cells and Differentiation: A Forkhead Box O Transcription Factor Perspective

Ludikhuize, M. C., & Colman, M. J. R. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8126 · Cited by 45 · see citing works

BMAL1 drives muscle repair through control of hypoxic NAD+ regeneration in satellite cellsPreprint

Zhu, P., Hamlish, N. X., Thakkar, A. V., Steffeck, A. W. T., Rendleman, E. J., Khan, N. H., Waldeck, N. J., DeVilbiss, A., Martin-Sandoval, M. S., Mathews, T. P., et al. (2022) · Genes & Development · doi:10.1101/gad.349066.121 · Cited by 43 · see citing works

Reduced electron transport chain complex I protein abundance and function in Mfn2‐deficient myogenic progenitors lead to oxidative stress and mitochondria swelling

Luo, N., Yue, F., Jia, Z., Chen, J., Deng, Q., Zhao, Y., & Kuang, S. (2021) · The FASEB Journal · doi:10.1096/fj.202002464r · Cited by 42 · see citing works

Evaluation of fermented soybean meal and edible insect hydrolysates as potential serum replacement in pig muscle stem cell culture

Kim, C. H., Lee, H. J., Jung, D. Y., Kim, M., Jung, H. Y., Hong, H., Choi, Y., Yong, H. I., & Jo, C. (2023) · Food Bioscience · doi:10.1016/j.fbio.2023.102923 · Cited by 37 · see citing works

Role of Metabolic Stress and Exercise in Regulating Fibro/Adipogenic Progenitors

Collao, N., Farup, J., & Lisio, M. D. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00009 · Cited by 37 · see citing works

Mitochondrial mechanisms in the pathogenesis of chronic inflammatory musculoskeletal disorders

Wu, K., Shieh, J.-S., Qin, L., & Guo, J. J. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01259-9 · Cited by 36 · see citing works

PDH‐mediated metabolic flow is critical for skeletal muscle stem cell differentiation and myotube formation during regeneration in mice

Hori, S., Hiramuki, Y., Nishimura, D., Sato, F., & Sehara‐Fujisawa, A. (2019) · The FASEB Journal · doi:10.1096/fj.201802479r · Cited by 36 · see citing works

α‐Synuclein aggregation causes muscle atrophy through neuromuscular junction degeneration

Yang, Q., Wang, Y., Zhao, C., Pang, S., Lu, J., & Chan, P. (2022) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13123 · Cited by 35 · see citing works

Regulation of Skeletal Muscle Satellite Cell Differentiation by Omega-3 Polyunsaturated Fatty Acids: A Critical Review

Isesele, P., & Mazurak, V. C. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.682091 · Cited by 33 · see citing works

Psat1-generated α-ketoglutarate and glutamine promote muscle stem cell activation and regenerationPreprint

Ciuffoli, V., Feng, X., Jiang, K., Acevedo-Luna, N., Ko, K. D., Wang, A. H. J., Riparini, G., Khateb, M., Glancy, B. C., Dell’Orso, S., et al. (2024) · Genes & Development · doi:10.1101/gad.351428.123 · Cited by 37 · see citing works

Skeletal muscle aging – Stem cells in the spotlight

Henze, H., Jung, M. J., Ahrens, H. E., Steiner, S., & von Maltzahn, J. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111283 · Cited by 28 · see citing works

The role of metabolism in cellular quiescence

Du, Y., Gupta, P., Qin, S., & Sieber, M. (2023) · Journal of Cell Science · doi:10.1242/jcs.260787 · Cited by 27 · see citing works

Paxbp1 controls a key checkpoint for cell growth and survival during early activation of quiescent muscle satellite cells

Zhou, S., Han, L., Weng, M., Zhu, H., Heng, Y., Wang, G., Shen, Z., Chen, X., Fu, X., Zhang, M., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2021093118 · Cited by 28 · see citing works

Metabolomics Analysis of Mesenchymal Stem Cells.

Goodarzi, P., Alavi-Moghadam, S., Payab, M., Larijani, B. A., Rahim, F., Gilany, K., Bana, N., Tayanloo-Beik, A., Heravani, N. F., Hadavandkhani, M., et al. (2019) · PubMed Central · doi:10.22088/ijmcm.bums.8.2.30 · Cited by 27 · see citing works

Ethanol-Impaired Myogenic Differentiation is Associated with Decreased Myoblast Glycolytic Function

Levitt, D., Chalapati, N., Prendergast, M. J., Simon, L., & Molina, P. (2020) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.14453 · Cited by 18 · see citing works

Perspectives on mitochondrial dysfunction in the regeneration of aging skeletal muscle

Wang, K., Gan, M., Lei, Y., Liao, T., Li, J., Niu, L., Zhao, Y., Chen, L., Wang, Y., Zhu, L., et al. (2025) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-025-00771-1 · Cited by 33 · see citing works

Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells

Choi, J., Seo, B. J., La, H., Yoon, S. H., Hong, Y. J., Lee, J.-H., Chung, H., Hong, K., & Tae, J. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101437 · Cited by 25 · see citing works

PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity

Cairns, G., Thumiah-Mootoo, M., Abbasi, M. R., Gourlay, M., Racine, J., Larionov, N., Prola, A., Khacho, M., & Burelle, Y. (2024) · Stem Cell Reports · doi:10.1016/j.stemcr.2024.03.004 · Cited by 23 · see citing works

Lactate Metabolism and Satellite Cell Fate

Nalbandian, M., Radak, Z. O., & Takeda, M. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.610983 · Cited by 24 · see citing works

Inhibiting uptake of extracellular vesicles derived from senescent bone marrow mesenchymal stem cells by muscle satellite cells attenuates sarcopenia

Dai, H., Wu, Z., Luo, J., Yu, G., Song, C., Wu, Y., & Xu, J. (2022) · Journal of Orthopaedic Translation · doi:10.1016/j.jot.2022.06.002 · Cited by 23 · see citing works

Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation

Yue, F., Gu, L., Qiu, J., Oprescu, S. N., Beckett, L. M., Ellis, J. M., Donkin, S. S., & Kuang, S. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00397-1 · Cited by 23 · see citing works

Impact of Magnetic Stimulation on Periodontal Ligament Stem Cells

Peluso, V., Rinaldi, L., Russo, T., Oliviero, O., Vito, A. D., Garbi, C., Giudice, A., Santis, R. D., Gloria, A., & D’Antò, V. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010188 · Cited by 22 · see citing works

Intestine-enriched apolipoprotein b orthologs are required for stem cell progeny differentiation and regeneration in planarians

Wong, L., Bruxvoort, C. G., Cejda, N. I., Delaney, M. R., Rodriguez-Otero, J., & Forsthoefel, D. J. (2022) · Nature Communications · doi:10.1038/s41467-022-31385-2 · Cited by 22 · see citing works

TNF‐ α ‐Induced KAT2A Impedes BMMSC Quiescence by Mediating Succinylation of the Mitophagy‐Related Protein VCP

Su, Z., Li, J., Lin, J., Li, Z., Che, Y., Zhang, Z., Guan, Z., Ye, G., Yu, W., Zeng, Y., et al. (2023) · Advanced Science · doi:10.1002/advs.202303388 · Cited by 20 · see citing works

Low-intensity pulsed ultrasound (LIPUS) promotes skeletal muscle regeneration by regulating PGC-1α/AMPK/GLUT4 pathways in satellite cells/myoblasts

Duan, H., Chen, S., Mai, X., Fu, L., Huang, L., Xiao, L., Liao, M., Chen, H., Liu, G., & Xie, L. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111097 · Cited by 20 · see citing works

Sestrins regulate muscle stem cell metabolic homeostasis

Yang, B. A., Castor‐Macias, J. A., Fraczek, P. M., Cornett, A. M., Brown, L. A., Kim, M., Brooks, S. V., Lombaert, I. M. A., Lee, J. H., & Aguilar, C. A. (2021) · Stem Cell Reports · doi:10.1016/j.stemcr.2021.07.014 · Cited by 20 · see citing works

GLUD1 determines murine muscle stem cell fate by controlling mitochondrial glutamate levels

Soro-Arnáiz, I., Fitzgerald, G., Cherkaoui, S., Zhang, J., Gilardoni, P. A., Ghosh, A., Bar‐Nur, O., Masschelein, E., Maechler, P., Zamboni, N., et al. (2024) · Developmental Cell · doi:10.1016/j.devcel.2024.07.015 · Cited by 20 · see citing works

Dormancy, Quiescence, and Diapause: Savings Accounts for Life

Ozguldez, H. O., & Bulut-Karslıoğlu, A. (2024) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-112122-022528 · Cited by 17 · see citing works

Mitochondrial Dynamics Drive Muscle Stem Cell Progression from Quiescence to Myogenic Differentiation

Sommers, O., Tomsine, R. A., & Khacho, M. (2024) · Cells · doi:10.3390/cells13211773 · Cited by 18 · see citing works

Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways

Vial, J., Huchedé, P., Fagault, S., Basset, F., Rossi, M., Geoffray, J., Soldati, H., Bisaccia, J., Elsensohn, M., Creveaux, M., et al. (2020) · Cell Death Discovery · doi:10.1038/s41420-020-00302-1 · Cited by 18 · see citing works

A Long Journey before Cycling: Regulation of Quiescence Exit in Adult Muscle Satellite Cells

Zhou, S., Han, L., & Wu, Z. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031748 · Cited by 18 · see citing works

Stem cell aging: The upcoming era of proteins and metabolites

Schüler, S. C., Gebert, N., & Ori‬‬, A. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111288 · Cited by 18 · see citing works

LMNA Mutations G232E and R482L Cause Dysregulation of Skeletal Muscle Differentiation, Bioenergetics, and Metabolic Gene Expression Profile

Ignatieva, E. V., Ivanova, O. A., Sorokina, M. Y., Khromova, N. V., Polev, D. E., Kostareva, A. A., Sergushichev, A., & Dmitrieva, R. I. (2020) · Genes · doi:10.3390/genes11091057 · Cited by 18 · see citing works

Muscle stem cell aging: identifying ways to induce tissue rejuvenation

Sousa‐Victor, P., Neves, J., & Muñoz‐Cánoves, P. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111246 · Cited by 18 · see citing works

Uncovering the prominent role of satellite cells in paravertebral muscle development and aging by single-nucleus RNA sequencing

Qiu, X., Wang, H., Yang, Z.-Y., Sun, L., Liu, S.-N., Fan, C., & Zhu, F. (2023) · Genes & Diseases · doi:10.1016/j.gendis.2023.01.005 · Cited by 17 · see citing works

3D bioprinted functional skeletal muscle models have potential applications for studies of muscle wasting in cancer cachexia

García‐Lizarribar, A., Villasante, A., Lopez-Martin, J. A., Flández, M., Soler‐Vázquez, M. C., Serra, D., Herrero, L., Sagrera, A. M. A. D. P., Efeyan, A., & Samitier, J. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213426 · Cited by 17 · see citing works

Adult Muscle Stem Cells: Exploring the Links Between Systemic and Cellular Metabolism

Purohit, G., & Dhawan, J. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00312 · Cited by 17 · see citing works

The Role of Mitochondrial and Redox Alterations in the Skeletal Myopathy Associated with Chronic Kidney Disease

Thome, T., Kim, K., Dong, G., & RYAN, T. E. (2022) · Antioxidants and Redox Signaling · doi:10.1089/ars.2022.0143 · Cited by 17 · see citing works

Muscle Injuries Induce a Prostacyclin‐PPARγ/PGC1a‐FAO Spike That Boosts Regeneration

Luo, L., Chua, B. Y.-J., Liu, T., Liang, K., Min‐Wen, J. C., Ma, W., Goh, J., Wang, Y., Su, J., Ho, Y. S., et al. (2023) · Advanced Science · doi:10.1002/advs.202301519 · Cited by 15 · see citing works

Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors

Pérez‐Díaz, S., Koumaiha, Z., Borok, M. J., Aurade, F., Pini, M., Periou, B., Rouault, C., Baba‐Amer, Y., Clément, K., Dérumeaux, G., et al. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.08.006 · Cited by 16 · see citing works

Metabolic regulation in adult and aging skeletal muscle stem cellsPreprint

Sartorelli, V., & Ciuffoli, V. (2024) · Genes & Development · doi:10.1101/gad.352277.124 · Cited by 18 · see citing works

MicroRNAs as the Sentinels of Redox and Hypertrophic Signalling

Kolodziej, F., McDonagh, B., Burns, N. C., & Goljanek‐Whysall, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314716 · Cited by 15 · see citing works

Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with age

Ramírez‐Pardo, I., Campanario, S., Chavda, B., Santiago‐Fernández, O., Flández, M., Grima-Terrén, M., Cisneros, A., Calls, A., Itzhak, D. N., Ngo, B., et al. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01411-w · Cited by 14 · see citing works

Autophagy in Muscle Regeneration: Mechanisms, Targets, and Therapeutic Perspective

Chu, Y., Yuan, X., Tao, Y., Yang, B. T., & Luo, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252211901 · Cited by 16 · see citing works

Single-cell analyses uncover granularity of muscle stem cells

Saber, J., Lin, A. Y., & Rudnicki, M. A. (2020) · F1000Research · doi:10.12688/f1000research.20856.1 · Cited by 13 · see citing works

Non-invasive Optical Biomarkers Distinguish and Track the Metabolic Status of Single Hematopoietic Stem Cells

Zhou, H., Nguyen, L., Arnesano, C., Ando, Y., Raval, M. H., Rodgers, J. T., Fraser, S. E., Lu, R., & Shen, K. (2020) · iScience · doi:10.1016/j.isci.2020.100831 · Cited by 13 · see citing works

Epigenetic metabolites license stem cell states

Somasundaram, L., Levy, S., Hussein, A. M., Ehnes, D. D., Mathieu, J., & Ruohola‐Baker, H. (2020) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2020.02.003 · Cited by 12 · see citing works

Metabolic Regulation of Stem Cells in Aging

Keller, A. R., Temple, T., Sayanjali, B., & Mihaylova, M. M. (2021) · Current Stem Cell Reports · doi:10.1007/s40778-021-00186-6 · Cited by 13 · see citing works

Pyruvate Kinase M2 Supports Muscle Progenitor Cell Proliferation but Is Dispensable for Skeletal Muscle Regeneration after Injury

Blum, J., Gheller, B. J. F., Benvie, A. M., Field, M. S., Panizza, E., Vacanti, N. M., Berry, D. C., & Thalacker‐Mercer, A. E. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab251 · Cited by 13 · see citing works

Epigenetic control of muscle stem cells: time for a new dimension

Bianconi, V., & Mozzetta, C. (2022) · Trends in Genetics · doi:10.1016/j.tig.2022.01.001 · Cited by 13 · see citing works

Dysregulated FOXO1 activity drives skeletal muscle intrinsic dysfunction in amyotrophic lateral sclerosis

Zufiría, M., Pikatza‐Menoio, O., Garciandia-Arcelus, M., Bengoetxea, X., Jiménez-Zúñiga, A., Elicegui, A., Levchuk, M., Arnold-García, O., Ondaro, J., Iruzubieta, P., et al. (2024) · Acta Neuropathologica · doi:10.1007/s00401-024-02794-y · Cited by 13 · see citing works

Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production

Sharrow, A. C., Megill, E., Chen, A. J., Farooqi, A., Tangudu, N. K., Uboveja, A., McGonigal, S. C., Hempel, N., Snyder, N. W., Buckanovich, R. J., et al. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.102031 · Cited by 11 · see citing works

Biophysical factors in the regulation of asymmetric division of stem cells

Barui, A., & Datta, P. (2018) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12479 · Cited by 12 · see citing works

In vitro-generated human muscle reserve cells are heterogeneous for Pax7 with distinct molecular states and metabolic profiles

Bouche, A., Borner, B., Richard, C., Grand, Y., Hannouche, D., & Laumonier, T. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03483-5 · Cited by 11 · see citing works

Importance of Nutrient Availability and Metabolism for Skeletal Muscle Regeneration

Blum, J., Epstein, R., Watts, S. A., & Thalacker‐Mercer, A. E. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.696018 · Cited by 12 · see citing works

Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration

Washington, T. A., Haynie, W. S., Schrems, E. R., Perry, R. A., Brown, L. A., Williams, B. M., Rosa‐Caldwell, M. E., Lee, D. E., & Brown, J. L. (2022) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2022.06.005 · Cited by 10 · see citing works

Fibro-adipogenic progenitor cells in skeletal muscle unloading: metabolic and functional impairments

Sorokina, M. Y., Bobkov, D. E., Хромова, Н. В., Vilchinskaya, N. A., Shenkman, B. S., Kostareva, A. A., & Dmitrieva, R. I. (2024) · Skeletal Muscle · doi:10.1186/s13395-024-00362-2 · Cited by 10 · see citing works

Cancer progression through the lens of age-induced metabolic reprogramming

Lazure, F., & Gomes, A. P. (2025) · Nature reviews. Cancer · doi:10.1038/s41568-025-00845-4 · Cited by 11 · see citing works

Chromatin accessibility profiling identifies evolutionary conserved loci in activated human satellite cells

Chow, L. S., Bosnakovski, D., Mashek, D. G., Kyba, M., Perlingeiro, R. C. R., & Magli, A. (2021) · Stem Cell Research · doi:10.1016/j.scr.2021.102496 · Cited by 9 · see citing works

Pluripotent stem cell-derived skeletal muscle fibers preferentially express myosin heavy-chain isoforms associated with slow and oxidative muscles

Incitti, T., Magli, A., Jenkins, A., Lin, K., Yamamoto, A., & Perlingeiro, R. C. R. (2020) · Skeletal Muscle · doi:10.1186/s13395-020-00234-5 · Cited by 8 · see citing works

Switching ubiquitous and muscle‐specific isoforms of mitochondrial respiratory complex IV in skeletal muscle fine‐tunes complex IV activity

Ye, X., Xie, Y., Shi, Y., Wang, B., Han, X., Zhou, X., Pan, K., Wang, M., & Fang, H. (2023) · The FASEB Journal · doi:10.1096/fj.202201223rr · Cited by 8 · see citing works

Metabolic Changes during In Vivo Maturation of PSC-Derived Skeletal Myogenic Progenitors

Abreu, P., Garay, B. I., Nemkov, T. G., Yamashita, A., & Perlingeiro, R. C. R. (2023) · Cells · doi:10.3390/cells13010076 · Cited by 8 · see citing works

Dynamic shifts in metabolic demand during myogenic progression in porcine skeletal muscle stem cells

Jung, D. Y., Lee, H. J., Lee, Y.-S., Kim, M., Lee, C., & Jo, C. (2025) · npj Science of Food · doi:10.1038/s41538-025-00480-1 · Cited by 7 · see citing works

Metabolic characterisation of skeletal muscle stem cells in distinct physiological states

Pala, F. (2017) · theses.fr (ABES) · doi:10.70675/ba751aadz6065z4221zbe6ez3b3e7cb993cc

Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation

Yue, F., Gu, L., Qiu, J., Oprescu, S. N., Beckett, L. M., Ellis, J. M., Donkin, S. S., & Kuang, S. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00397-1 · Cited by 23 · see citing works

High Throughput Screening of Mitochondrial Bioenergetics in Myoblasts and Differentiated Myotubes

Takeda, K., Takemasa, T., & Fujita, R. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3036-5_7 · Cited by 4 · see citing works

Mitochondria in muscle stem cell biology: gatekeepers of fate, function, and regeneration

Khacho, M., & Burelle, Y. (2026) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00027.2026 · Cited by 2 · see citing works

Mitochondrial Dynamics Drive Muscle Stem Cell Progression from Quiescence to Myogenic Differentiation

Sommers, O., Tomsine, R. A., & Khacho, M. (2024) · Cells · doi:10.3390/cells13211773 · Cited by 18 · see citing works