A Research Strategy to Discover the Environmental Causes of Autism and Neurodevelopmental Disabilities
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Direct evidence linking any specific EDC to a clearly defined clinical disorder involving the social brain is sparse, and no single chemical has yet been definitively implicated.
“Direct evidence linking any specific EDC to a clearly defined clinical disorder involving the social brain is sparse, and no single chemical has yet been definitively implicated (18, 21–25).”
From Endocrine Disruption of Vasopressin Systems and Related Behaviors (2017) · cites this paper as [18]
Single genetic anomalies account for only a small proportion of affected ASD cases.
“Although ASD is considered one of the most heritable neurodevelopmental disorders [ 12 , 13 ], single genetic anomalies account for only a small proportion of affected cases [ 14 , 15 ].”
From DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders? (2016) · cites this paper as [15]
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- Authors
- Landrigan, P. J., Lambertini, L., & Birnbaum, L. S.
- Affiliations
- National Institutes of Health (US)
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-07-01
- Volume
- 120
- Issue
- 7
- Pages
- a258-a260
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- PMC
- PMC3404655
- OpenAlex
- W2037056332
- Cited by
- 230
- References
- 36
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 9 · 2023: 15 · 2022: 16 · 2021: 14 · 2020: 23 · 2019: 21 · 2018: 22 · 2017: 23 · 2016: 19 · 2015: 18 · 2014: 26 · 2013: 9 · 2012: 5
- FWCI
- 1.47
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- public-domain
- creativecommons.org/licenses/by/4.0/ (vor, 2007 d)
- Locations
- Environmental Health Perspectives (publishedVersion, public-domain)
- Europe PMC (PubMed Central) (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Keywords
- autism spectrum disorder, neurodevelopmental disorders, environmental causes, environmental risk factors, research strategies
- MeSH terms
- Autistic Disorder, Developmental Disabilities, Environmental Exposure, Humans
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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