Is Personality a Key Predictor of Missing Study Data? An Analysis From a Randomized Controlled Trial
Open accessAbstract
PURPOSE: Little is known regarding the effects of psychological factors on data collection in research studies. We examined whether Five Factor Model (FFM) personality factors-Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness-predicted missing data in a randomized controlled trial (RCT). METHODS: Individuals (N = 415) aged 40 years and older with various chronic conditions, plus basic activity impairment, depressive symptoms, or both, were recruited from a primary care network and enrolled in a 6-week RCT of an illness self-management intervention, delivered by means of home visits or telephone calls or usual care. Random effects logistic regression modeling was used to examine whether FFM factors predicted missing illness management self-efficacy data at any scheduled follow-up (2, 4, and 6 weeks, and 6 and 12 months), controlling for disease burden, study arm, and sociodemographic characteristics. RESULTS: Across all follow-up points, the missing data rate was 4.5%. Higher levels of Openness (adjusted odds ratio [AOR] for 1-SD increase = 0.24; 95% CI, 0.12-0.46; P <.001), Agreeableness (AOR = 0.29; CI 0.14-0.60; P=.001), and Conscientiousness (AOR = 0.24; CI 0.15-0.50; P <.001) were independently associated with fewer missing data. Accuracy of the missing data prediction model increased when personality variables were added (change in area under the receiver operating characteristic curve from 0.71 to 0.77; chi(2)(1)=6.6; P=.01). CONCLUSIONS: Personality was a powerful predictor of missing study data in this RCT. Assessing personality could inform efforts to enhance data completion and adjust analyses for bias caused by missing data.
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Adherence to medication and study drop-out appear to be related to personality characteristics.
“Adherence to medication and study drop-out alike appears to be related to personality characteristics [265–267].”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [266]
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Self-citation
- Authors
- Jerant, A., Chapman, B. P., Duberstein, P., & Franks, P.
- Affiliations
- University of California Davis Medical Center (US)
- University of Rochester Medicine (US)
- Venue
- The Annals of Family Medicine
- Publisher
- Annals of Family Medicine
- Published
- 2009-03-01
- Volume
- 7
- Issue
- 2
- Pages
- 148-156
- ISSN
- 1544-1709 (ISSN-L)
- 1544-1717
- PMC
- PMC2653957
- OpenAlex
- W2136787969
- Cited by
- 29
- References
- 58
- Citations by year
- 2026: 3 · 2025: 1 · 2023: 1 · 2022: 1 · 2017: 3 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 2 · 2012: 2
- FWCI
- 4.96
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- The Annals of Family Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Agency for Healthcare Research and Quality (R01HS013603)
- National Institute on Aging (K08AG031328, L30 AG031021)
- National Institute of Mental Health (K24MH072712, T32MH073452)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Social Sciences › Sociology and Political Science › Survey Methodology and Nonresponse
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Keywords
- missing data, personality, Big Five personality traits, openness to experience, agreeableness, conscientiousness, self-efficacy, data completion, chronic disease, depressive symptoms, primary care
- MeSH terms
- Adult, Aged, Aged, 80 and over, Data Interpretation, Statistical, Female, Humans, Male, Middle Aged, Patient Compliance, Patient Dropouts, Personality, Primary Health Care, Psychometrics, Self Care, Bias, Logistic Models, Randomized Controlled Trials as Topic
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