The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Genomic Ancestry of North Africans Supports Back-to-Africa Migrations
Open accessAbstract
North African populations are distinct from sub-Saharan Africans based on cultural, linguistic, and phenotypic attributes; however, the time and the extent of genetic divergence between populations north and south of the Sahara remain poorly understood. Here, we interrogate the multilayered history of North Africa by characterizing the effect of hypothesized migrations from the Near East, Europe, and sub-Saharan Africa on current genetic diversity. We present dense, genome-wide SNP genotyping array data (730,000 sites) from seven North African populations, spanning from Egypt to Morocco, and one Spanish population. We identify a gradient of likely autochthonous Maghrebi ancestry that increases from east to west across northern Africa; this ancestry is likely derived from "back-to-Africa" gene flow more than 12,000 years ago (ya), prior to the Holocene. The indigenous North African ancestry is more frequent in populations with historical Berber ethnicity. In most North African populations we also see substantial shared ancestry with the Near East, and to a lesser extent sub-Saharan Africa and Europe. To estimate the time of migration from sub-Saharan populations into North Africa, we implement a maximum likelihood dating method based on the distribution of migrant tracts. In order to first identify migrant tracts, we assign local ancestry to haplotypes using a novel, principal component-based analysis of three ancestral populations. We estimate that a migration of western African origin into Morocco began about 40 generations ago (approximately 1,200 ya); a migration of individuals with Nilotic ancestry into Egypt occurred about 25 generations ago (approximately 750 ya). Our genomic data reveal an extraordinarily complex history of migrations, involving at least five ancestral populations, into North Africa.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“We then used ALDER40 to estimate the time of a putative pulse-like admixture event, which was estimated to have occurred 24 generations ago (700 years ago), consistent with previous results from Henn and colleagues16.”
From Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods (2017) · cites this paper as [16]
The cited source says what the claim attributes to it.
In the citing paper
“By comparing ancient individuals from Abusir el-Meleq with modern Egyptian reference populations, we found an influx of sub-Saharan African ancestry after the Roman Period, which corroborates the findings by Henn and colleagues16.”
From Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods (2017) · cites this paper as [16]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
PLINK: a tool set for whole-genome association and population-based linkage analyses.
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., Maller, J., Sklar, P., de Bakker, P. I. W., Daly, M. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/519795 · Cited by 34,089
Fast model-based estimation of ancestry in unrelated individuals
Alexander, D. H., Novembre, J., & Lange, K. (2009) · Genome Research · doi:10.1101/gr.094052.109 · Cited by 9,898
Browning, S. R., & Browning, B. L. (2007) · The American Journal of Human Genetics · doi:10.1086/521987 · Cited by 3,217
Integrating common and rare genetic variation in diverse human populations
The International HapMap 3 Consortium (2010) · Nature · doi:10.1038/nature09298 · Cited by 3,026
Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation
Li, J. Z., Absher, D. M., Tang, H., Southwick, A. M., Casto, A. M., Ramachandran, S., Cann, H. M., Barsh, G. S., Feldman, M. W., Cavalli-Sforza, L. L., et al. (2008) · Science · doi:10.1126/science.1153717 · Cited by 1,915
Genetics in geographically structured populations: defining, estimating and interpreting FST
Holsinger, K. E., & Weir, B. S. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2611 · Cited by 1,480
A worldwide survey of haplotype variation and linkage disequilibrium in the human genome
Conrad, D. F., Jakobsson, M., Coop, G., Wen, X., Wall, J. D., Rosenberg, N. A., & Pritchard, J. K. (2006) · Nature Genetics · doi:10.1038/ng1911 · Cited by 546
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations
Price, A. L., Tandon, A., Patterson, N., Barnes, K. C., Rafaels, N., Ruczinski, I., Beaty, T. H., Mathias, R., Reich, D., & Myers, S. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000519 · Cited by 539
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
Henn, B. M., Gignoux, C. R., Jobin, M., Granka, J. M., Macpherson, J. M., Kidd, J. M., Rodríguez-Botigué, L., Ramachandran, S., Hon, L., Brisbin, A., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017511108 · Cited by 502
Self-citationGenome-wide patterns of population structure and admixture in West Africans and African Americans
Bryc, K., Auton, A., Nelson, M. R., Oksenberg, J. R., Hauser, S. L., Williams, S., Froment, A., Bodo, J.-M., Wambebe, C., Tishkoff, S. A., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909559107 · Cited by 455
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Inference of population splits and mixtures from genome-wide allele frequency data
Pickrell, J. K., & Pritchard, J. K. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002967 · Cited by 2,731
Genomic insights into the origin of farming in the ancient Near East
Lazaridis, I., Nadel, D., Rollefson, G., Merrett, D. C., Rohland, N., Mallick, S., Fernandes, D., Novak, M., Gamarra, B., Sirak, K., et al. (2016) · Nature · doi:10.1038/nature19310 · Cited by 955
Self-citationA genetic atlas of human admixture history
Hellenthal, G., Busby, G. B. J., Band, G., Wilson, J. F., Capelli, C., Falush, D., & Myers, S. (2014) · Science · doi:10.1126/science.1243518 · Cited by 798
Evaluating the Use of ABBA–BABA Statistics to Locate Introgressed Loci
Martin, S. H., Davey, J. W., & Jiggins, C. D. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu269 · Cited by 740
Did Our Species Evolve in Subdivided Populations across Africa, and Why Does It Matter?
Scerri, E. M. L., Thomas, M., Manica, A., Gunz, P., Stock, J. T., Stringer, C. B., Grove, M. L., Groucutt, H. S., Timmermann, A., Rightmire, G. P., et al. (2018) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2018.05.005 · Cited by 514
Self-citationThe genetics of Mexico recapitulates Native American substructure and affects biomedical traits
Moreno-Estrada, A., Gignoux, C. R., Fernández-López, J. C., Zakharia, F., Sikora, M., Contreras, A. V., Acuña-Alonzo, V., Sandoval, K., Eng, C., Romero-Hidalgo, S., et al. (2014) · Science · doi:10.1126/science.1251688 · Cited by 478
Self-citationNew insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing
Keller, A., Graefen, A., Ball, M., Matzas, M., Boisguerin, V., Maixner, F., Leidinger, P., Backes, C., Khairat, R., Forster, M., et al. (2012) · Nature Communications · doi:10.1038/ncomms1701 · Cited by 437
Self-citationHenn, B. M., Cavalli-Sforza, L. L., & Feldman, M. W. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1212380109 · Cited by 414
Self-citationCharacterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery
Greater Middle East Variome Consortium, Scott, E. M., Halees, A., Itan, Y., Spencer, E. G., He, Y., Azab, M. A., Gabriel, S. B., Belkadi, A., Boisson, B., et al. (2016) · Nature Genetics · doi:10.1038/ng.3592 · Cited by 376
The Geography of Recent Genetic Ancestry across Europe
Ralph, P. L., & Coop, G. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001555 · Cited by 384
Age of the Association between Helicobacter pylori and Man
Moodley, Y., Linz, B., Bond, R. P., Nieuwoudt, M., Soodyall, H., Schlebusch, C. M., Bernhöft, S., Hale, J. L., Suerbaum, S., Mugisha, L., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002693 · Cited by 358
Population Genetics Models of Local Ancestry
Gravel, S. (2012) · Genetics · doi:10.1534/genetics.112.139808 · Cited by 311
Self-citationAdmixture into and within sub-Saharan Africa
Busby, G., Band, G., Le, S. Q., Jallow, M., Bougama, E., Mangano, V. D., Amenga-Etego, L. N.-K., Enimil, A. K., Apinjoh, T. O., Ndila, C., et al. (2016) · eLife · doi:10.7554/elife.15266 · Cited by 293
Toward a new history and geography of human genes informed by ancient DNA
Pickrell, J. K., & Reich, D. (2014) · Trends in Genetics · doi:10.1016/j.tig.2014.07.007 · Cited by 276
Genomic Insights into the Ancestry and Demographic History of South America
Homburger, J. R., Moreno‐Estrada, A., Gignoux, C. R., Nelson, D., Sánchez, E., Ortiz-Tello, P. A., Pons‐Estel, B. A., Acevedo‐Vásquez, E. M., Miranda, P., Langefeld, C. D., et al. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005602 · Cited by 269
Self-citationDistance from sub-Saharan Africa predicts mutational load in diverse human genomes
Henn, B. M., Botigué, L. R., Peischl, S., Dupanloup, I., Lipatov, M., Maples, B. K., Martin, A. R., Musharoff, S. A., Cann, H. M., Snyder, M. P., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1510805112 · Cited by 268
Self-citationUganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa
Gurdasani, D., Carstensen, T., Fatumo, S., Chen, G., Franklin, C. S., Prado-Martinez, J., Bouman, H. J., Abascal, F., Haber, M., Tachmazidou, I., et al. (2019) · Cell · doi:10.1016/j.cell.2019.10.004 · Cited by 255
Dannemann, M., Andrés, A. M., & Kelso, J. (2016) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.11.015 · Cited by 249
Fast and accurate inference of local ancestry in Latino populations
Baran, Y., Paşaniuc, B., Sankararaman, S., Torgerson, D. G., Gignoux, C. R., Eng, C. S., Rodríguez-Cintrón, W., Chapela, R., Ford, J. G., Avila, P. C., et al. (2012) · Bioinformatics · doi:10.1093/bioinformatics/bts144 · Cited by 242
Pagani, L., Kivisild, T., Tarekegn, A., Ekong, R., Plaster, C., Gallego Romero, I., Ayub, Q., Mehdi, S. Q., Thomas, M. G., Luiselli, D., et al. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2012.05.015 · Cited by 230
Fregel, R., Mendez, F. L., Bokbot, Y., Socas, D. M., Massieu, M. D. C., Santana, J., Morales, J., Ávila‐Arcos, M. C., Underhill, P. A., Shapiro, B., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800851115 · Cited by 231
Self-citationPagani, L., Schiffels, S., Gurdasani, D., Danecek, P., Scally, A., Chen, Y., Xue, Y., Haber, M., Ekong, R., Oljira, T., et al. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.04.019 · Cited by 216
Self-citationGenetic Origins of Lactase Persistence and the Spread of Pastoralism in Africa
Ranciaro, A., Campbell, M. C., Hirbo, J. B., Ko, W., Froment, A., Anagnostou, P., Kotze, M. J., Ibrahim, M. E., Nyambo, T., Omar, S. A., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.02.009 · Cited by 215
Schuenemann, V. J., Peltzer, A., Welte, B., van Pelt, W. P., Molak, M., Wang, C.-C., Furtwängler, A., Urban, C., Reiter, E., Nieselt, K., et al. (2017) · Nature Communications · doi:10.1038/ncomms15694 · Cited by 201
Gene flow from North Africa contributes to differential human genetic diversity in southern Europe
Botigué, L. R., Henn, B. M., Gravel, S., Maples, B. K., Gignoux, C. R., Corona, E., Atzmon, G., Burns, E., Ostrer, H., Flores, C., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1306223110 · Cited by 199
Self-citationFan, S., Kelly, D. E., Beltrame, M. H., Hansen, M. E. B., Mallick, S., Ranciaro, A., Hirbo, J., Thompson, S., Beggs, W., Nyambo, T., et al. (2019) · Genome Biology · doi:10.1186/s13059-019-1679-2 · Cited by 194
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population
Chimusa, E. R., Zaitlen, N., Daya, M., Möller, M., van Helden, P. D., Mulder, N., Price, A. L., & Hoal, E. G. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt462 · Cited by 182
Al-Hendy, A. A., Halder, Allah, A., Roshdy, Rajaratnam, & Sabry, M. (2013) · International Journal of Women s Health · doi:10.2147/ijwh.s38800 · Cited by 164
Human Dispersal Out of Africa: A Lasting Debate
López, S., van Dorp, L., & Hellenthal, G. (2015) · Evolutionary Bioinformatics · doi:10.4137/ebo.s33489 · Cited by 168
Genetic Variation and Adaptation in Africa: Implications for Human Evolution and DiseasePreprint
Gomez, F., Hirbo, J. B., & Tishkoff, S. A. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008524 · Cited by 161
Wang, K., Goldstein, S. T., Bleasdale, M., Clist, B., Bostoen, K. A. G., Bakwa-Lufu, P., Buck, L. T., Crowther, A., Dème, A., McIntosh, R. J., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaz0183 · Cited by 145
Tales of Human Migration, Admixture, and Selection in Africa
Schlebusch, C. M., & Jakobsson, M. (2018) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-083117-021759 · Cited by 144
The spatiotemporal patterns of major human admixture events during the European Holocene
Chintalapati, M., Patterson, N. J., & Moorjani, P. (2022) · eLife · doi:10.7554/elife.77625 · Cited by 143
Corbett-Detig, R. B., & Nielsen, R. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006529 · Cited by 134
A Spatial Framework for Understanding Population Structure and Admixture
Bradburd, G. S., Ralph, P. L., & Coop, G. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1005703 · Cited by 126
The Lengths of Admixture Tracts
Liang, M., & Nielsen, R. (2014) · Genetics · doi:10.1534/genetics.114.162362 · Cited by 127
The First Modern Human Dispersals across Africa
Rito, T., Richards, M. B., Fernandes, V., Alshamali, F., Černý, V., Pereira, L., & Soares, P. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080031 · Cited by 118
Martin, A. R., Atkinson, E. G., Chapman, S. B., Stevenson, A., Stroud, R. E., Abebe, T., Akena, D. H., Alemayehu, M., Ashaba, F. K., Atwoli, L., et al. (2021) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2021.03.012 · Cited by 119
Shriner, D. (2013) · Current Protocols in Human Genetics · doi:10.1002/0471142905.hg0123s76 · Cited by 111
African population history: an ancient DNA perspective
Vicente, M., & Schlebusch, C. M. (2020) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2020.05.008 · Cited by 111
The genetic structure of the Turkish population reveals high levels of variation and admixture
Kars, M. E., Başak, A. N., Onat, O. E., Bilgüvar, K., Choi, J., Itan, Y., Çağlar, C., Palvadeau, R. J., Casanova, J., Cooper, D. N., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2026076118 · Cited by 110
Peris, D., Langdon, Q. K., Moriarty, R. V., Sylvester, K., Bontrager, M., Charron, G., Leducq, J., Landry, C. R., Libkind, D., & Hittinger, C. T. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006155 · Cited by 108
The history and evolution of the Denisovan- EPAS1 haplotype in Tibetans
Zhang, X., Witt, K. E., Bañuelos, M. M., Ko, A., Yuan, K., Xu, S., Nielsen, R., & Huerta-Sanchez, E. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2020803118 · Cited by 105
Genomic history of the Sardinian population
Chiang, C. W. K., Marcus, J. H., Sidore, C., Biddanda, A., Al-Asadi, H., Żołędziewska, M., Pitzalis, M., Busonero, F., Maschio, A., Pistis, G., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0215-8 · Cited by 108
Human variation in the shape of the birth canal is significant and geographically structured
Betti, L., & Manica, A. (2018) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2018.1807 · Cited by 104
Complex Ancient Genetic Structure and Cultural Transitions in Southern African Populations
Montinaro, F., Busby, G., González‐Santos, M., Oosthuitzen, O., Oosthuitzen, E., Anagnostou, P., Destro‐Bisol, G., Pascali, V. L., & Capelli, C. (2016) · Genetics · doi:10.1534/genetics.116.189209 · Cited by 102
Bycroft, C., Fernández–Rozadilla, C., Ruíz-Ponte, C., Quintela, I., Carracedo, Á., Donnelly, P., & Myers, S. (2019) · Nature Communications · doi:10.1038/s41467-018-08272-w · Cited by 102
Chromosome Painting In Silico in a Bacterial Species Reveals Fine Population Structure
Yahara, K., Furuta, Y., Oshima, K., Yoshida, M., Azuma, T., Hattori, M., Uchiyama, I., & Kobayashi, I. (2013) · Molecular Biology and Evolution · doi:10.1093/molbev/mst055 · Cited by 98
Capellini, T. D., Chen, H., Cao, J., Doxey, A. C., Kiapour, A. M., Schoor, M., & Kingsley, D. M. (2017) · Nature Genetics · doi:10.1038/ng.3911 · Cited by 100
Kidd, J. M., Gravel, S., Byrnes, J., Moreno-Estrada, A., Musharoff, S., Bryc, K., Degenhardt, J. D., Brisbin, A., Sheth, V., Chen, R., et al. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2012.08.025 · Cited by 95
Self-citationVarela, R., Günther, T., Krzewińska, M., Storå, J., Gillingwater, T. H., MacCallum, M., Arsuaga, J. L., Dobney, K. M., Valdiosera, C. E., Jakobsson, M., et al. (2017) · Current Biology · doi:10.1016/j.cub.2017.09.059 · Cited by 96
Early Back-to-Africa Migration into the Horn of Africa
Hodgson, J. A., Mulligan, C. J., Al‐Meeri, A., & Raaum, R. L. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004393 · Cited by 93
Hollfelder, N., Schlebusch, C. M., Günther, T., Babiker, H. M. A., Hassan, H. Y., & Jakobsson, M. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006976 · Cited by 94
Brandt, S., Hildebrand, E., Vogelsang, R., Wolfhagen, J., & Wang, H. (2016) · Journal of Archaeological Science Reports · doi:10.1016/j.jasrep.2016.09.013 · Cited by 90
Constraint, natural selection, and the evolution of human body form
Savell, K. R. R., Auerbach, B. M., & Roseman, C. C. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1603632113 · Cited by 85
Life in Deserts: The Genetic Basis of Mammalian Desert Adaptation
Rocha, J. L., Godinho, R., Brito, J. C., & Nielsen, R. (2021) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2021.03.007 · Cited by 88
Consanguinity and Inbreeding in Health and Disease in North African Populations
Romdhane, L., Mezzi, N., Hamdi, Y., El‐Kamah, G. Y., Barakat, A., & Abdelhak, S. (2019) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-083118-014954 · Cited by 82
North African Populations Carry the Signature of Admixture with Neandertals
Sánchez‐Quinto, F., Botigué, L. R., Civit, S., Arenas, C., Ávila‐Arcos, M. C., Bustamante, C. D., Comas, D., & Lalueza‐Fox, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047765 · Cited by 86
Self-citationRecent historical migrations have shaped the gene pool of Arabs and Berbers in North Africa
Arauna, L. R., Mendoza‐Revilla, J., Mas-Sandoval, À., Izaabel, H., Bekada, A., Benhamamouch, S., Fadhlaoui‐Zid, K., Zalloua, P., Hellenthal, G., & Comas, D. (2016) · Molecular Biology and Evolution · doi:10.1093/molbev/msw218 · Cited by 82
Self-citationLorente-Galdos, B., Lao, O., Serra-Vidal, G., Santpere, G., Kuderna, L. F. K., Arauna, L. R., Fadhlaoui-Zid, K., Pimenoff, V. N., Soodyall, H., Zalloua, P., et al. (2019) · Genome Biology · doi:10.1186/s13059-019-1684-5 · Cited by 77
Self-citationThe Critical Needs and Challenges for Genetic Architecture Studies in Africa
Martin, A. R., Teferra, S., Möller, M., Hoal, E. G., & Daly, M. J. (2018) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2018.08.005 · Cited by 76
A survey of sub-Saharan gene flow into the Mediterranean at risk loci for coronary artery disease
Álvarez‐Álvarez, M. M., Zanetti, D., Carreras‐Torres, R., Moral, P., & Athanasiadis, G. I. (2017) · European Journal of Human Genetics · doi:10.1038/ejhg.2016.200 · Cited by 79
The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape
Dobón, B., Hassan, H. Y., Laayouni, H., Luisi, P., Ricaño-Ponce, I., Zhernakova, A., Wijmenga, C., Tahir, H., Comas, D., Netea, M. G., et al. (2015) · Scientific Reports · doi:10.1038/srep09996 · Cited by 77
Self-citationMaritime route of colonization of Europe
Paschou, P., Petros Drineas, B., Yannaki, E., Razou, A., Kanaki, K., Tsetsos, F., Padmanabhuni, S. S., Michalodimitrakis, M., Renda, M. C., Pavlović, S., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1320811111 · Cited by 84
Human ancestry correlates with language and reveals that race is not an objective genomic classifier
Baker, J. L., Rotimi, C. N., & Shriner, D. (2017) · Scientific Reports · doi:10.1038/s41598-017-01837-7 · Cited by 78
Ecogeographic variation across morphofunctional units of the human nose
Maddux, S. D., Butaric, L. N., Yokley, T. R., & Franciscus, R. G. (2016) · American Journal of Physical Anthropology · doi:10.1002/ajpa.23100 · Cited by 74
Solé‐Morata, N., García-Fernández, C., Urasin, V., Bekada, A., Fadhlaoui‐Zid, K., Zalloua, P., Comas, D., & Calafell, F. (2017) · Scientific Reports · doi:10.1038/s41598-017-16271-y · Cited by 75
Self-citationThe Archaeological and Genetic Correlates of Amazigh Linguistics
Fentress, E. (2019) · Cambridge University Press eBooks · doi:10.1017/9781108634311.016 · Cited by 66
Inferring ancestry from population genomic data and its applications
Padhukasahasram, B. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00204 · Cited by 68
Asiimwe, I. G., Zhang, E. J., Osanlou, R., Krause, A., Dillon, C., Suarez‐Kurtz, G., Zhang, H., Perini, J. A., Renta, J. Y., Duconge-Soler, J., et al. (2019) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1755 · Cited by 65
Bekada, A., Fregel, R., Cabrera, V. M., Larruga, J. M., Pestano, J., Benhamamouch, S., & González, A. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056775 · Cited by 65
Inference of historical migration rates via haplotype sharing
Palamara, P. F., & Pe’er, I. (2013) · Bioinformatics · doi:10.1093/bioinformatics/btt239 · Cited by 68
Chimusa, E. R., Daya, M., Möller, M., Ramesar, R., Henn, B. M., van Helden, P. D., Mulder, N., & Hoal, E. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073971 · Cited by 66
Self-citationEvolutionary Genetics and Admixture in African Populations
Pfennig, A., Petersen, L. N., Kachambwa, P., & Lachance, J. (2023) · Genome Biology and Evolution · doi:10.1093/gbe/evad054 · Cited by 62
Divorcing the Late Upper Palaeolithic demographic histories of mtDNA haplogroups M1 and U6 in Africa
Pennarun, E., Kivisild, T., Metspalu, E., Metspalu, M., Reisberg, T., Moisan, J., Behar, D. M., Jones, S., & Villems, R. (2012) · BMC Evolutionary Biology · doi:10.1186/1471-2148-12-234 · Cited by 61
Shriner, D., Ayele, F. T., Adeyemo, A., & Rotimi, C. N. (2014) · Scientific Reports · doi:10.1038/srep06055 · Cited by 64
Bosse, M., Megens, H., Madsen, O., Frantz, L., Paudel, Y., Crooijmans, R. P. M. A., & Groenen, M. A. M. (2014) · Molecular Ecology · doi:10.1111/mec.12807 · Cited by 66
Yan-hu, L., Wang, L., Xu, T., Guo, X., Li, Y., Yin, T., Yang, H., Hu, Y., Adeola, A. C., Sanke, O. J., et al. (2017) · Molecular Biology and Evolution · doi:10.1093/molbev/msx258 · Cited by 59
Gebremeskel, E. I., & Ibrahim, M. E. (2014) · European Journal of Human Genetics · doi:10.1038/ejhg.2014.41 · Cited by 57
North African Jewish and non-Jewish populations form distinctive, orthogonal clusters
Campbell, C. L., Palamara, P. F., Dubrovsky, M., Botigué, L. R., Fellous, M., Atzmon, G., Oddoux, C., Pearlman, A. W., Hao, L., Henn, B. M., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1204840109 · Cited by 57
Self-citationsppIDer: A Species Identification Tool to Investigate Hybrid Genomes with High-Throughput Sequencing
Langdon, Q. K., Peris, D., Kyle, B., & Hittinger, C. T. (2018) · Molecular Biology and Evolution · doi:10.1093/molbev/msy166 · Cited by 59
Majara, L., Kalungi, A., Koen, N., Tsuo, K., Wang, Y., Gupta, R., Nkambule, L. L., Zar, H. J., Stein, D. J., Kinyanda, E., et al. (2023) · Human Genetics and Genomics Advances · doi:10.1016/j.xhgg.2023.100184 · Cited by 65
Vicente, M., Priehodová, E., Diallo, I., Podgorná, E., Poloni, E. S., Černý, V., & Schlebusch, C. M. (2019) · BMC Genomics · doi:10.1186/s12864-019-6296-7 · Cited by 58
Northwest African Neolithic initiated by migrants from Iberia and Levant
Simões, L. G., Günther, T., Sánchez, R. M. M., Rodríguez, J. C. V., Iriarte, E., Varela, R., Bokbot, Y., Valdiosera, C. E., & Jakobsson, M. (2023) · Nature · doi:10.1038/s41586-023-06166-6 · Cited by 59
The Arab genome: Health and wealth
Zayed, H. (2016) · Gene · doi:10.1016/j.gene.2016.07.007 · Cited by 54
The peopling of the African continent and the diaspora into the new world
Campbell, M. C., Hirbo, J. B., Townsend, J. P., & Tishkoff, S. A. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2014.09.003 · Cited by 56
A unique Toxoplasma gondii haplotype accompanied the global expansion of cats
Galal, L., Ariey, F., Gouilh, M. A., Dardé, M., Hamidović, A., Letourneur, F., Prugnolle, F., & Mercier, A. (2022) · Nature Communications · doi:10.1038/s41467-022-33556-7 · Cited by 52
Scheinfeldt, L., Soi, S., Lambert, C. A., Ko, W., Coulibaly, A., Ranciaro, A., Thompson, S. R., Hirbo, J. B., Beggs, W. R., Ibrahim, M. E., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1817678116 · Cited by 52
Genome-Wide and Paternal Diversity Reveal a Recent Origin of Human Populations in North Africa
Fadhlaoui-Zid, K., Haber, M., Martínez-Cruz, B., Zalloua, P., Benammar Elgaaied, A., & Comas, D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080293 · Cited by 52
Self-citationAcross language families: Genome diversity mirrors linguistic variation within E urope
Longobardi, G., Ghirotto, S., Guardiano, C., Tassi, F., Benazzo, A., Ceolin, A., & Barbujani, G. (2015) · American Journal of Physical Anthropology · doi:10.1002/ajpa.22758 · Cited by 52
The genomic history of the indigenous people of the Canary Islands
Serrano, J. G., Ordóñez, A. C., Santana, J., Sánchez‐Cañadillas, E., Arnay, M., Rodríguez, A. R., Morales, J., Vázquez, J. V., Barroso, V. A., Delgado‐Darias, T., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-40198-w · Cited by 52
Self-citationGenetic Heterogeneity in Algerian Human Populations
Bekada, A., Arauna, L. R., Deba, T., Calafell, F., Benhamamouch, S., & Comas, D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0138453 · Cited by 47
Self-citationHeterogeneity in Palaeolithic Population Continuity and Neolithic Expansion in North Africa
Serra-Vidal, G., Lucas-Sánchez, M., Fadhlaoui‐Zid, K., Bekada, A., Zalloua, P., & Comas, D. (2019) · Current Biology · doi:10.1016/j.cub.2019.09.050 · Cited by 47
Self-citationSantos, P., Fortes, G. G., Trucchi, E., Ceolin, A., Cordoni, G., Guardiano, C., Longobardi, G., & Barbujani, G. (2020) · Genes · doi:10.3390/genes11121491 · Cited by 47
Early modern human dispersal from Africa: genomic evidence for multiple waves of migration
Tassi, F., Ghirotto, S., Mezzavilla, M., Vilaça, S. T., De Santi, L., & Barbujani, G. (2015) · Investigative Genetics · doi:10.1186/s13323-015-0030-2 · Cited by 41
Giuliani, C., Sazzini, M., Bacalini, M. G., Pirazzini, C., Marasco, E., Fontanesi, E., Franceschi, C., Luiselli, D., & Garagnani, P. (2016) · Genome Biology and Evolution · doi:10.1093/gbe/evw186 · Cited by 49
Nine things to remember about human genome diversity
Barbujani, G., Ghirotto, S., & Tassi, F. (2013) · Tissue Antigens · doi:10.1111/tan.12165 · Cited by 48
The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population
Ouhaïbi-Djellouli, H., Médiène-Benchekor, S., Lardjam-Hetraf, S. A., Hamani-Medjaoui, I., Meroufel, D. N., Boulenouar, H., Hermant, X., Saïdi‐Mehtar, N., Amouyel, P., Houti, L., et al. (2014) · BMC Genetics · doi:10.1186/s12863-014-0134-3 · Cited by 45
The rs1421085 variant within FTO promotes brown fat thermogenesis
Zhang, Z., Chen, N., Yin, N., Liu, R., He, Y., Li, D., Tong, M., Gao, A., Lu, P., Zhao, Y., et al. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00847-2 · Cited by 45
Self-citationEthnic Diversity and Warfarin Pharmacogenomics
Asiimwe, I. G., & Pirmohamed, M. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.866058 · Cited by 44
Metadata
- Authors
- Henn, B. M., Botigué, L. R., Gravel, S., Wang, W., Brisbin, A., Byrnes, J. K., Fadhlaoui-Zid, K., Zalloua, P. A., Moreno-Estrada, A., Bertranpetit, J., Bustamante, C. D., & Comas, D.
- Affiliations
- Stanford University (US)
- Consejo Superior de Investigaciones Científicas (ES)
- Cornell University (US)
- Lebanese American University (LB)
- Corresponding author
- Bustamante, Carlos D.
- Comas, David
- ORCID
- Venue
- PLoS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2012-01-12
- Volume
- 8
- Issue
- 1
- Pages
- e1002397
- ISSN
- 1553-7390 (ISSN-L)
- 1553-7404
- PMC
- PMC3257290
- OpenAlex
- W2059277852
- Cited by
- 331
- References
- 46
- Citations by year
- 2026: 11 · 2025: 25 · 2024: 16 · 2023: 26 · 2022: 11 · 2021: 29 · 2020: 16 · 2019: 28 · 2018: 29 · 2017: 27 · 2016: 29 · 2015: 22 · 2014: 26 · 2013: 23 · 2012: 13
- FWCI
- 16.19
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS Genetics (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RECERCAT (Consorci de Serveis Universitaris de Catalunya) (publishedVersion, other-oa)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- eScholarship (California Digital Library) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Repositori digital de la UPF (Universitat Pompeu Fabra) (submittedVersion, other-oa)
- Greater South Information System
- Funders
- Generalitat de Catalunya (2009SGR1101)
- National Institutes of Health
- National Human Genome Research Institute (R01HG003229)
- National Institute of General Medical Sciences (R01GM083606)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Social Sciences › Anthropology › Race, Genetics, and Society
- Keywords
- Berber populations, migration timing, local ancestry, Morocco
- MeSH terms
- Egypt, Ancient, Africa, Northern, DNA, Mitochondrial, Emigration and Immigration, Europe, Gene Pool, Genotype, Haplotypes, Humans, Middle East, Morocco, Population, Population Dynamics, Genetic Variation, Africa South of the Sahara, Polymorphism, Single Nucleotide, Genomics, Black People, White People, History, Ancient, Gene Flow
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
