YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

Gene Ontology: tool for the unification of biology

Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., et al. (2000) · Nature Genetics · doi:10.1038/75556 · Cited by 43,206

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome.

Langmead, B., Trapnell, C., Pop, M., & Salzberg, S. L. (2009) · Genome Biology · doi:10.1186/gb-2009-10-3-r25 · Cited by 21,849

Model-based Analysis of ChIP-Seq (MACS)

Zhang, Y., Liu, T., Meyer, C. A., Eeckhoute, J., Johnson, D. S., Bernstein, B. E., Nusbaum, C., Myers, R. M., Brown, M., Li, W., et al. (2008) · Genome Biology · doi:10.1186/gb-2008-9-9-r137 · Cited by 18,386

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

Cerami, E., Gao, J., Dogrusoz, U., Gross, B. E., Sumer, S. O., Aksoy, B. A., Jacobsen, A., Byrne, C. J., Heuer, M. L., Larsson, E., et al. (2012) · Cancer Discovery · doi:10.1158/2159-8290.cd-12-0095 · Cited by 17,455

Differential expression analysis for sequence count data

Anders, S., & Huber, W. (2010) · Genome Biology · doi:10.1186/gb-2010-11-10-r106 · Cited by 15,581

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Trapnell, C., Williams, B. A., Pertea, G., Mortazavi, A., Kwan, G., van Baren, M. J., Salzberg, S. L., Wold, B. J., & Pachter, L. (2010) · Nature Biotechnology · doi:10.1038/nbt.1621 · Cited by 15,556

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

Gao, J., Aksoy, B. A., Dogrusoz, U., Dresdner, G., Gross, B., Sumer, S. O., Sun, Y., Jacobsen, A., Sinha, R., Larsson, E., et al. (2013) · Science Signaling · doi:10.1126/scisignal.2004088 · Cited by 15,160

The Human Genome Browser at UCSC

Kent, W. J., Sugnet, C. W., Furey, T. S., Roskin, K. M., Pringle, T. H., Zahler, A. M., & Haussler, A. D. (2002) · Genome Research · doi:10.1101/gr.229102 · Cited by 10,400

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Creyghton, M. P., Cheng, A. W., Welstead, G. G., Kooistra, T., Carey, B. W., Steine, E. J., Hanna, J., Lodato, M. A., Frampton, G. M., Sharp, P. A., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016071107 · Cited by 4,302

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

Siepel, A., Bejerano, G., Pedersen, J. S., Hinrichs, A. S., Hou, M., Rosenbloom, K., Clawson, H., Spieth, J., Hillier, L. W., Richards, S., et al. (2005) · Genome Research · doi:10.1101/gr.3715005 · Cited by 3,971 · cited 1×

Integrin‐FAK‐CDC42‐PP1A signaling gnaws at YAP/TAZ activity to control incisor stem cells

Hicks‐Berthet, J., & Varelas, X. (2017) · BioEssays · doi:10.1002/bies.201700116 · Cited by 25

YAP and TAZ, the conductors that orchestrate eye development, homeostasis, and disease

Zhu, J., Lin, S., & Ye, J. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26870 · Cited by 23

Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma

Robinson, M. H., Maximov, V. D., Lallani, S. B., Farooq, H., Taylor, M. D., Read, R. D., & Kenney, A. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-50088-1 · Cited by 24

Loss of ANCO1 repression at AIB1/YAP targets drives breast cancer progression

Kushner, M. H., Ory, V., Graham, G. T., Sharif, G. M., Kietzman, W. B., Thevissen, S., Yuan, M., Schmidt, M. O., Wellstein, A., & Riegel, A. T. (2019) · EMBO Reports · doi:10.15252/embr.201948741 · Cited by 24

Corosolic Acid Inhibits Cancer Progress Through Inactivating YAP in Hepatocellular Carcinoma

Jia, M., Xiong, Y., Li, M., & Mao, Q. (2020) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504020x15853075736554 · Cited by 24

Decoding YAP dependent transcription in the liver

Biagioni, F., Croci, O., Sberna, S., Donato, E., Sabò, A., Bisso, A., Curti, L., Chiesa, A., & Campaner, S. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac624 · Cited by 22

YAP1 Withdrawal in Hepatoblastoma Drives Therapeutic Differentiation of Tumor Cells to Functional Hepatocyte‐Like Cells

Smith, J. L., Rodríguez, T., Mou, H., Kwan, S., Pratt, H., Zhang, X., Cao, Y., Liang, S., Özata, D. M., Yu, T., et al. (2020) · Hepatology · doi:10.1002/hep.31389 · Cited by 23

The Moonlighting Function of Glutaminase 2 Promotes Immune Evasion of Pancreatic Ductal Adenocarcinoma by Tubulin Tyrosine Ligase-like 1-Mediated Yes1 Associated Transcriptional Regulator Glutamylation

Chen, X., Fu, H., Zhu, S., Xiang, Z., Fu, H. Y., Sun, Z., Zhang, S., Zheng, X., Hu, X., Chao, M., et al. (2025) · Gastroenterology · doi:10.1053/j.gastro.2025.01.240 · Cited by 22

Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration

Fetiva, M. C., Liss, F., Gertzmann, D., Thomas, J., Gantert, B., Vogl, M., Sira, N., Weinstock, G., Kneitz, S., Ade, C. P., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad107 · Cited by 22

Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens

Barbosa, I. A. M., Gopalakrishnan, R., Mercan, S., Mourikis, T. P., Martin, T., Wengert, S., Sheng, C., Ji, F., Lopes, R., Knehr, J., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-39527-w · Cited by 23

Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development

Rozengurt, E., & Eibl, G. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i15.1797 · Cited by 22

Reduced growth rate of aged muscle stem cells is associated with impaired mechanosensitivity

Haroon, M. F., Boers, H. E., Bakker, A. D., Bloks, N. G. C., Hoogaars, W. M. H., Giordani, L., Musters, R. J. P., Deldicque, L., Koppo, K., Grand, F. L., et al. (2022) · Aging · doi:10.18632/aging.203830 · Cited by 22

The role of Hippo‐YAP/TAZ signaling in brain development

Terry, B. K., & Kim, S. (2022) · Developmental Dynamics · doi:10.1002/dvdy.504 · Cited by 23

A SMAD1/5-YAP signaling module drives radial glia self-amplification and growth of the developing cerebral cortex

Najas, S., Pijuan, I., Esteve‐Codina, A., Usieto, S., Martinez, J. D., Zwijsen, A., Arbonés, M. L., Martı́, E., & Dréau, G. L. (2020) · Development · doi:10.1242/dev.187005 · Cited by 24

Age-dependent changes in nuclear-cytoplasmic signaling in skeletal muscle

Iyer, S. R., Hsia, R., Folker, E. S., & Lovering, R. M. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111338 · Cited by 22

Investigating underlying molecular mechanisms, signaling pathways, emerging therapeutic approaches in pancreatic cancer

Mustafa, M., Abbas, K., Alam, M., Habib, S., Zulfareen, Hasan, G. M., Islam, S., Shamsi, A., & Hassan, M. I. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1427802 · Cited by 25

Spatial regulation of expanded transcription in the Drosophila wing imaginal disc

Wang, L.-H., & Baker, N. E. (2018) · PLoS ONE · doi:10.1371/journal.pone.0201317 · Cited by 18

DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis

Ritchey, L., Ha, T., Otsuka, A., Kabashima, K., Wang, D., Wang, Y., Lowy, D. R., & Tosato, G. (2019) · Oncogene · doi:10.1038/s41388-019-0944-x · Cited by 17

RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer

Prokakis, E., Jansari, S., Boshnakovska, A., Wiese, M., Kusch, K., Kramm, C. M., Dullin, C., Rehling, P., Glatzel, M., Pantel, K., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06157-5 · Cited by 18

Hippo pathway in cell–cell communication: emerging roles in development and regeneration

Nita, A., & Moroishi, T. (2024) · Inflammation and Regeneration · doi:10.1186/s41232-024-00331-8 · Cited by 23

Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer

Kotagiri, S., Blazanin, N., Xi, Y., Han, Y., Qudratullah, M., Liang, X., Wang, Y., Pandey, P., Mazhar, H., Lam, T., et al. (2024) · Cell chemical biology · doi:10.1016/j.chembiol.2024.09.004 · Cited by 18

Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development

Arriagada, C., Lin, E., Schonning, M. J., & Astrof, S. (2024) · Developmental Cell · doi:10.1016/j.devcel.2024.09.017 · Cited by 17

Research progress of ankyrin repeat domain 1 protein: an updated review

Xu, X., Wang, X., Yu, L., Chen, R., Wen, H., Wang, Y., & Ma, G. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00647-w · Cited by 19

Glucocorticoids Promote Extracellular Matrix Component Remodeling by Activating YAP in Human Retinal Capillary Endothelial Cells

Gu, X., Ge, L., Ren, B., Fang, Y., Li, Y., Wang, Y., & Xu, H. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.738341 · Cited by 16

Expanded Potential Stem Cells from Human Embryos Have an Open Chromatin Configuration with Enhanced Trophoblast Differentiation Ability

Chen, A. C. H., Lee, Y. L., Ruan, H., Huang, W. M., Fong, S. W., Tian, S. I. P., Lee, K. C., Wu, G. M., Tan, Y., Wong, T. C. H., et al. (2023) · Advanced Science · doi:10.1002/advs.202204797 · Cited by 16

Myeloid Zinc Finger 1 and GA Binding Protein Co-Operate with Sox2 in Regulating the Expression of Yes-Associated Protein 1 in Cancer Cells

Verma, N., Gadi, A., Maurizi, G., Roy, U. B., Mansukhani, A., & Basilico, C. (2017) · Stem Cells · doi:10.1002/stem.2705 · Cited by 16

YAP1-mediated regulation of mitochondrial dynamics in IDH1 mutant gliomas

Patrick, S., Gowda, P., Lathoria, K., Suri, V. S., & Sen, E. (2021) · Journal of Cell Science · doi:10.1242/jcs.259188 · Cited by 17

A Yap-dependent mechanoregulatory program sustains cell migration for embryo axis assembly

Sousa‐Ortega, A., Vázquez-Marín, J., Sanabria‐Reinoso, E., Corbacho, J., Polvillo, R., Campoy-López, A., Buono, L., Loosli, F., Almuedo‐Castillo, M., & Martínez‐Morales, J. R. (2023) · Nature Communications · doi:10.1038/s41467-023-38482-w · Cited by 15

Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription

Kulkarni, A., Mohan, V., Tang, T. T.-L., Post, L. E., Chan, Y.-C., Manning, M., Thio, N., Parker, B. L., Dawson, M. A., Rosenbluh, J., et al. (2024) · EMBO Reports · doi:10.1038/s44319-024-00217-3 · Cited by 17

An emergent Wnt5a/YAP/TAZ regulatory circuit and its possible role in cancer

Astudillo, P. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.10.001 · Cited by 14

Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment

Hazra, R., Brine, L., Garcia, L. A., Benz, B. A., Chirathivat, N., Shen, M. M., Wilkinson, J. E., Lyons, S. K., & Spector, D. L. (2022) · Developmental Cell · doi:10.1016/j.devcel.2022.10.002 · Cited by 16

Yap1b, a divergent Yap/Taz family member, cooperates with yap1 in survival and morphogenesis via common transcriptional targets

Vázquez-Marín, J., Gutierrez-Triana, J. A., Almuedo‐Castillo, M., Buono, L., Gómez-Skármeta, J. L., Mateo, J. L., Wittbrodt, J., & Martínez‐Morales, J. R. (2019) · Development · doi:10.1242/dev.173286 · Cited by 15

Clinical potential of the Hippo-YAP pathway in bladder cancer

Cheng, X., Lou, K., Ding, L., Zou, X., Huang, R., Xu, G., Zou, J., & Zhang, G. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.925278 · Cited by 13

HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling

Uppala, R., Sarkar, M. K., Young, K. Z., Ma, F., Vemulapalli, P., Wasikowski, R., Plazyo, O., Swindell, W. R., Maverakis, E. M., Gharaee‐Kermani, M., et al. (2024) · iScience · doi:10.1016/j.isci.2024.108986 · Cited by 13

Osteogenic differentiation of bone mesenchymal stem cells on linearly aligned triangular micropatterns

Zeng, Y., Shen, J., Zhou, X., Ouyang, Z., Zhong, J., Qin, Y., Jin, L., He, X., Li, L., Xie, J., et al. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb01218f · Cited by 13

Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor–Targeted Therapy Drives Resistance in Breast Cancer

Gemma, C., Lai, C., Singh, A. K., Belfiore, A., Portman, N., Milioli, H. H., Periyasamy, M., Raafat, S., Nicholls, A. J., Davies, C. M., et al. (2024) · Cancer Research · doi:10.1158/0008-5472.can-24-0013 · Cited by 15

HNF4α and CDX2 Regulate Intestinal YAP1 Promoter Activity

Larsen, S., Davidsen, J., Dahlgaard, K., Pedersen, O. B., & Troelsen, J. T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20122981 · Cited by 13

A Feedback Loop Regulation Of LINC01433 And YAP Promotes Malignant Behavior In Gastric Cancer Cells

Cao, Z., Qian, H., Liu, K., Zhao, W., & Wang, L. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s222903 · Cited by 13

Emerging Insights Into the Role of the Hippo Pathway in Multiple Myeloma and Associated Bone Disease

Kyriazoglou, A. I., Ntanasis‐Stathopoulos, I., Terpos, E., Fotiou, D., Kastritis, E., Dimopoulos, M. A., & Gavriatopoulou, M. (2019) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/j.clml.2019.09.620 · Cited by 12

Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway

Wan, W., Miao, Y., Niu, Y., Zhu, K., Ma, Y., Pan, M., Ma, B., & Wei, Q. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03273-z · Cited by 13

Activation of Mechanosensitive Transcription Factors in Murine C2C12 Mesenchymal Precursors by Focused Low-Intensity Pulsed Ultrasound (FLIPUS)

Puts, R., Rikeit, P., Ruschke, K., Kadow‐Romacker, A., Hwang, S., Jenderka, K., Knaus, P. I., & Raum, K. (2016) · IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control · doi:10.1109/tuffc.2016.2586972 · Cited by 12

TAZ Represses the Neuronal Commitment of Neural Stem Cells

Robledinos-Antón, N., Escoll, M., Guan, K., & Cuadrado, A. (2020) · Cells · doi:10.3390/cells9102230 · Cited by 12

CRKL Enhances YAP Signaling through Binding and JNK/JUN Pathway Activation in Liver Cancer

Wesener, M. C., Weiler, S. M. E., Bissinger, M., Klessinger, T. F., Rose, F., Merker, S., Luzarowski, M., Ruppert, T., Helm, B., Klingmüller, U., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158549 · Cited by 13

The oncogenic axis YAP/MYC/EZH2 impairs PTEN tumor suppression activity enhancing lung tumorigenicity

Sardo, F. L., Turco, C., Messina, B., Sacconi, A., Auciello, F. R., Pulito, C., Strano, S., Lev, S., & Blandino, G. (2024) · Cell Death Discovery · doi:10.1038/s41420-024-02216-8 · Cited by 12

The TEA domain transcription factors TEAD1 and TEAD3 and WNT signaling determine HLA-G expression in human extravillous trophoblasts

Gu, B., Ferreira, L. M. R., Herrera, S., Brown, L., Lieberman, J., Sherwood, R. I., Meissner, T. B., & Strominger, J. (2025) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2425339122 · Cited by 11

A subset of transposable elements as mechano-response enhancer elements in controlling human embryonic stem cell fate

Sun, T., Xu, Y., Angel, N., Chen, L., Zhang, K., Hoffman, B. D., Ou, J., Meng, Z., Varghese, S., & Diao, Y. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01770-2 · Cited by 12

Heptadecanoic Acid, an Odd-Chain Fatty Acid, Induces Apoptosis and Enhances Gemcitabine Chemosensitivity in Pancreatic Cancer Cells

Kim, H. Y., Moon, J. Y., & Cho, S. K. (2023) · Journal of Medicinal Food · doi:10.1089/jmf.2022.k.0061 · Cited by 12

Hypoxia‐induced YAP activation and focal adhesion turnover to promote cell migration in mesenchymal TNBC cells

Nguyen, T. M. H., Lai, Y., Chen, Y., Lin, T., Nguyen, N. T., & Chiu, W. (2023) · Cancer Medicine · doi:10.1002/cam4.5680 · Cited by 11

The novel YAP target gene, SGK1, upregulates TAZ activity by blocking GSK3β-mediated TAZ destabilization

Yoo, G., Kim, T., Chung, C., Hwang, D.-S., & Lim, D. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.06.092 · Cited by 13

A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth

Kurlishchuk, Y. V., Vranesic, A. C., Jessen, M., Kipping, A., Ritter, C., Kim, K., Cramer, P., & von Eyß, B. (2024) · The EMBO Journal · doi:10.1038/s44318-024-00188-0 · Cited by 10

A Role for the Hippo/ YAP1 Pathway in the Regulation of In Vitro Vasculogenic Mimicry in Glioblastoma Cells

Roy, M.-È., Elimam, R., Zgheib, A., & Annabi, B. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70304 · Cited by 11

Podocyte-specific YAP activation triggers crescentic glomerulonephritis through cross-talk with parietal epithelial cells

Turinsky, L., Rehrl, S., Nguyen, C., Benyahia, S., Kuperwasser, N., Vasseur, F., Arevalo, A. R., Rabant, M., Goudin, N., Mesnard, L., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adq7825 · Cited by 11

α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration

Tang, Y., Thiess, L., Weiler, S. M. E., Tóth, M., Rose, F., Merker, S., Ruppert, T., Schirmacher, P., & Breuhahn, K. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01169-2 · Cited by 10

Adaptation trajectories during adhesion and spreading affect future cell states

Bruekers, S. M. C., Bao, M., Hendriks, J. M. A., Mulder, K. W., & Huck, W. T. S. (2017) · Scientific Reports · doi:10.1038/s41598-017-12467-4 · Cited by 10

Characterization of mice carrying a conditional TEAD1 allele

Wen, T., Yin, Q., Yu, L., Hu, G., Liu, J., Zhang, W., Huang, L., Su, H., Wang, M., & Zhou, J. (2017) · genesis · doi:10.1002/dvg.23085 · Cited by 9

Low complexity domains, condensates, and stem cell pluripotency

Vodnala, M., Choi, E., & Fong, Y. W. (2021) · World Journal of Stem Cells · doi:10.4252/wjsc.v13.i5.416 · Cited by 10

A narrative review for the Hippo-YAP pathway in cancer survival and immunity: the Yin-Yang dynamics

Wang, R., & Zhu, G. (2021) · Translational Cancer Research · doi:10.21037/tcr-21-1843 · Cited by 9

Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities

Ghomlaghi, M., Theocharous, M., Hoang, N., Shin, S., von Kriegsheim, A., Neill, E. O., Zhang, T., & Nguyen, L. K. (2024) · iScience · doi:10.1016/j.isci.2024.109031 · Cited by 10

O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts

Very, N., Boulet, C., Gheeraert, C., Berthier, A., Johanns, M., Saleh, M. B., Guille, L., Bray, F., Strub, J., Bobowski, M., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06773-9 · Cited by 12

Hydrogel Enhanced Organoid Multidirectional Differentiation via Yap/Tead4 Mechanotransduction for Accelerated Tissue Regeneration

Luo, P., Cheng, Y., Luo, Y., Zhang, N., Cao, J., Wang, H., Jiang, X., Wang, Q., Wu, X., Liu, Y., et al. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5c06161 · Cited by 11

The Hippo terminal effector YAP boosts enterovirus replication in type 1 diabetes

Geravandi, S., Liu, H., Pahwa, H., Madduri, M. K., Atawneh, F. H., Feriz, A. M., Rafizadeh, S., Kruf, A. E., Khazaei, M., BAHRAMI, P., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64508-6 · Cited by 10

Luciferase Reporter Assays to Determine YAP/TAZ Activity in Mammalian Cells

Dupont, S. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8910-2_11 · Cited by 9

Heterogeneous RNA editing and influence of ADAR2 on mesothelioma chemoresistance and the tumor microenvironment

Hariharan, A., Qi, W., Rehrauer, H., Wu, L., Ronner, M., Wipplinger, M., Kresoja‐Rakic, J., Sun, S., Oton, L., Sculco, M., et al. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13322 · Cited by 9

Spontaneously evolved progenitor niches escape Yap oncogene addiction in advanced pancreatic ductal adenocarcinomas

Murakami, S., White, S. M., McIntosh, A. T., Nguyen, C. D. K., & Yi, C. (2023) · Nature Communications · doi:10.1038/s41467-023-37147-y · Cited by 9

TEAD4 predicts poor prognosis and transcriptionally targets PLAGL2 in serous ovarian cancer

Tong, X., Liu, Y.-S., Tong, R., Tang, W., Li, X., Wang, C., & Wang, Y. (2023) · Human Cell · doi:10.1007/s13577-023-00908-4 · Cited by 9

Chromatin dynamics underlying the precise regeneration of a vertebrate limb – Epigenetic regulation and cellular memory

Hayashi, S., Tamura, K., & Yokoyama, H. (2019) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2019.04.006 · Cited by 10

Comparative Transcriptome Analysis on the Regulatory Mechanism of Thoracic Ganglia in Eriocheir sinensis at Post-Molt and Inter-Molt Stages

Wang, M., Zhou, J., Su, S., Tang, Y., Xu, G., Li, J., Yu, F. D., Li, H., Song, C., Liang, M., et al. (2022) · Life · doi:10.3390/life12081181 · Cited by 9

Quantitative Real-Time PCR to Measure YAP/TAZ Activity in Human Cells

Cao, X., & Zhao, B. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8910-2_12 · Cited by 9

The stabilization of yes‐associated protein by TGFβ‐activated kinase 1 regulates the self‐renewal and oncogenesis of gastric cancer stem cells

Wang, G., Sun, Q., Zhu, H. H., Bi, Y., Zhu, H., & Xu, A. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16660 · Cited by 8

Human Satellite 3 DNA encodes megabase-scale transcription factor binding platformsPreprint

Franklin, J. M., Dubocanin, D., Chittenden, C., Barillas, A., Lee, R. J., Ghosh, R. P., Gerton, J. L., Guan, K., & Altemose, N. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.22.616524 · Cited by 11

Role of the YAP/TAZ-TEAD Transcriptional Complex in the Metabolic Control of TRAIL Sensitivity by the Mevalonate Pathway in Cancer Cells

Yousfi, Y. E., Mora-Molina, R., López‐Rivas, A., & Yerbes, R. (2023) · Cells · doi:10.3390/cells12192370 · Cited by 8

YAP/TEAD involvement in resistance to paclitaxel chemotherapy in lung cancer

Brosseau, S., Abreu, P., Bouchez, C., Charon, L., Kieffer, Y., Gentric, G., Picant, V., Veith, I., Camonis, J., Descroix, S., et al. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-04949-7 · Cited by 8

Increased ANKRD1 Levels in Early Senescence Mediated by RBMS1-Elicited ANKRD1 mRNA Stabilization

Shin, C. H., Rossi, M. S., Anerillas, C., Martindale, J. L., Yang, X., Ji, E., Pal, A., Munk, R. B., Yang, J., Tsitsipatis, D., et al. (2024) · Molecular and Cellular Biology · doi:10.1080/10985549.2024.2350540 · Cited by 8

Pits and CtBP Control Tissue Growth in Drosophila melanogaster with the Hippo Pathway Transcription Repressor Tgi

Vissers, J. H. A., Dent, L., House, C. M., Kondo, S., & Harvey, K. F. (2020) · Genetics · doi:10.1534/genetics.120.303147 · Cited by 7

The role of Hippo pathway signaling and A-kinase anchoring protein 13 in primordial follicle activation and inhibition

Maher, J. Y., Islam, M. S., Yin, O., Brennan, J. T., Gough, E. K., Driggers, P. H., & Segars, J. H. (2022) · F&S Science · doi:10.1016/j.xfss.2022.03.002 · Cited by 8

De novo identification of universal cell mechanics gene signaturesPreprint

Urbanska, M., Ge, Y., Winzi, M., Abuhattum, S., Ali, S. S., Herbig, M., Kräter, M., Toepfner, N., Durgan, J., Florey, O., et al. (2023) · eLife · doi:10.7554/elife.87930 · Cited by 8

HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury

Yuan, W.-C., Earl, A. S., Ma, S., Alcedo, K., Russell, J. O., Duarte, F. M., Chu, Y.-T., Chang, P.-C., Chen, H.-Y., Chi, H.-H., et al. (2025) · Cell Stem Cell · doi:10.1016/j.stem.2025.04.010 · Cited by 7

Interpreting regulatory mechanisms of Hippo signaling through a deep learning sequence model

Dalal, K., McAnany, C. E., Weilert, M., McKinney, M. C., Krueger, S., & Zeitlinger, J. (2025) · Cell Genomics · doi:10.1016/j.xgen.2025.100821 · Cited by 7

Sustained YAP/TAZ activation promotes aberrant alveolar epithelial cell differentiation and drives persistent fibrotic remodeling

Gaona, I. P., McCall, A. S., Geis, N. M., Colvard, A. C., DiGiovanni, G. T., Sherrill, T. P., Singha, U. K., Nichols, D. S., Serezani, A. P. M., David, H. E., et al. (2026) · JCI Insight · doi:10.1172/jci.insight.198113 · Cited by 10

Interferon-γ selectively promotes survival of alveolar progenitor cells in a human lung organoid model

Dost, A. F. M., Balážová, K., Casellas, C. P., Rooijen, L. V., Epskamp, W., van Son, G. J. F., van de Wetering, W. J., López‐Iglesias, C., Begthel, H., Peters, P. J., et al. (2026) · The EMBO Journal · doi:10.1038/s44318-026-00774-4 · Cited by 7

Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers

Jessen, M., Gertzmann, D., Liss, F., Zenk, F., Bähner, L., Schöffler, V., Schulte, C., Maric, H. M., Ade, C. P., von Eyß, B., et al. (2024) · Oncogene · doi:10.1038/s41388-023-02926-w · Cited by 7

TGFβ and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas

NIPPER, M. J., Xu, Y., Liu, J., Yin, X., Liu, Z., Ye, Z., Zhang, J., Chen, Y., & Wang, P. (2024) · Cells · doi:10.3390/cells13020186 · Cited by 8

Concerted localization-resets precede YAP-dependent transcriptionPreprint

Ghosh, R. P., Franklin, J. M., Shi, Q., Reddick, M. P., & Liphardt, J. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/539049 · Cited by 8

Adenovirus small E1A directs activation of Alu transcription at YAP/TEAD- and AP-1-bound enhancers through interactions with the EP400 chromatin remodeler

Cantarella, S., Vezzoli, M., Carnevali, D., Morselli, M., Zemke, N. R., Montanini, B., Daussy, C. F., Wodrich, H., Teichmann, M., Pellegrini, M. A., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae615 · Cited by 6

Nanofiber-microwell cell culture system for spatially patterned differentiation of pluripotent stem cells in 3D

Tai, Y., Goodrich, R. N., Maldonado, M., Ortiz, J., Martinez, J., Ico, G., Ko, A. Y. M. A., Shih, H.-P., & Nam, J. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101109 · Cited by 6

The JNK and Hippo pathways control epithelial integrity and prevent tumor initiation by regulating an overlapping transcriptome

Mitchell, K. A., Vissers, J. H. A., Pojer, J. M., Brooks, E., Hilmi, A. J. S., Papenfuss, A. T., Schröder, J., & Harvey, K. F. (2024) · Current Biology · doi:10.1016/j.cub.2024.07.060 · Cited by 6

Aggressive high-grade NF2 mutant meningiomas downregulate oncogenic YAP signaling via the upregulation of VGLL4 and FAT3/4

Parrish, A. G., Arora, S., Thirimanne, H. N., Rudoy, D., Schmid, S., Sievers, P., Sahm, F., Holland, E. C., & Szulzewsky, F. (2024) · Neuro-Oncology Advances · doi:10.1093/noajnl/vdae148 · Cited by 6

Mechanical strain treatment improves nuclear transfer reprogramming efficiency by enhancing chromatin accessibility

Chen, Y., Xu, R., Zhou, S. Y., Zhao, C., Hu, Z., Hua, Y., Xiong, Y., Liu, X., Lü, J., Sun, Y., et al. (2023) · Stem Cell Reports · doi:10.1016/j.stemcr.2023.02.007 · Cited by 6

Aberrant expression of NPPB through YAP1 and TAZ activation in mesothelioma with Hippo pathway gene alterations

Sato, T., Akao, K., Sato, A., Tsujimura, T., Mukai, S., & Sekido, Y. (2023) · Cancer Medicine · doi:10.1002/cam4.6056 · Cited by 6

Reuse of Molecules for Glioblastoma Therapy

Koehler, A., Karve, A. S., Desai, P. B., Arbiser, J. L., Plas, D. R., Qi, X., Read, R. D., Sasaki, A. T., Gawali, V. S., Toukam, D. K., et al. (2021) · Pharmaceuticals · doi:10.3390/ph14020099 · Cited by 6

De novo identification of universal cell mechanics gene signaturesPreprint

Urbanska, M., Ge, Y., Winzi, M., Abuhattum, S., Ali, S. S., Herbig, M., Kräter, M., Toepfner, N., Durgan, J., Florey, O., et al. (2023) · eLife · doi:10.7554/elife.87930.1 · Cited by 6

Mud Loss Restricts Yki-Dependent Hyperplasia in Drosophila Epithelia

Parra, A. S., & Johnston, C. A. (2020) · Journal of Developmental Biology · doi:10.3390/jdb8040034 · Cited by 5

Arsenic impairs stem cell differentiation via the Hippo signaling pathway

Perego, M. C., McMichael, B. D., & Bain, L. J. (2023) · Toxicology Research · doi:10.1093/toxres/tfad018 · Cited by 5

The association between the expression of nuclear Yes-associated protein 1 (YAP1) and p53 protein expression profile in breast cancer patients

Cha, Y. J., Kim, D., Bae, S. J., Ahn, S. G., Jeong, J., Cho, M. K., Paik, P. S., Yoo, T.-K. R., Park, W. C., & Yoon, C. I. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250986 · Cited by 5

Specific Overexpression of YAP in Vascular Smooth Muscle Attenuated Abdominal Aortic Aneurysm Formation by Activating Elastic Fiber Assembly via LTBP4

Liu, Y., Lv, X., Chen, X., Meng, Y., Guo, L., Liu, G., Liu, Y., & Jiang, H. (2022) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-022-10278-1 · Cited by 5

Chromatin accessibility profiles of castration-resistant prostate cancers reveal novel subtypes and therapeutic vulnerabilitiesPreprint

Tang, F., Wang, S., Wong, C. K., Lee, C. J., Cohen, S. M., Park, J., Hill, C. E., Eng, K., Bareja, R., Han, T., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.26.355925 · Cited by 4

De novo identification of universal cell mechanics gene signaturesPreprint

Urbanska, M., Ge, Y., Winzi, M., Abuhattum, S., Ali, S. S., Herbig, M., Kräter, M., Toepfner, N., Durgan, J., Florey, O., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.26.441418 · Cited by 5

Multiple gravitational lensing

Laurent Nottale, A., & Chauvineau, B. (1986) · Cited by 5

Proteomic insights into circadian transcription regulation: novel E-box interactors revealed by proximity labelingPreprint

Torres, M., Kirchner, M., Marks, C. G., Mertins, P., & Kramer, A. (2024) · Genes & Development · doi:10.1101/gad.351836.124 · Cited by 4

Hippo in smooth muscle - a therapeutic target in vascular diseases driven by aging and hypertension

Albinsson, S., Rippe, C., Daoud, F., Bastrup, J., Holmberg, J., Jepps, T. A., & Swärd, K. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1674714 · Cited by 4

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

Zanconato, F., Forcato, M., Battilana, G., Azzolin, L., Quaranta, E., Bodega, B., Rosato, A., Bicciato, S., Cordenonsi, M., & Piccolo, S. (2015) · Nature Cell Biology · doi:10.1038/ncb3216 · Cited by 1,219

Abstract B37: Genomic view of YAP1 dependent transcription

Biagioni, F., Croci, O., Donato, E., Sberna, S., Fazio, S., Sabò, A., Amati, B. B., & Campaner, S. (2020) · Molecular Cancer Research · doi:10.1158/1557-3125.hippo19-b37

YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers

Galli, G. G., Carrara, M., Yuan, W.-C., Valdes-Quezada, C., Gurung, B., Pepe-Mooney, B., Zhang, T., Geeven, G., Gray, N. S., de Laat, W., et al. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.09.001 · Cited by 290

Hippo signaling regulates the nuclear behavior and DNA binding times of YAP and TEAD to control transcription

Kroeger, B., Manning, S. A., Mohan, V., Deng, Q., 楼洁琼, Sun, G., Lamont, S., McCann, A. J., François, M., Polo, J. M., et al. (2025) · Science Advances · doi:10.1126/sciadv.adw4974 · Cited by 13

Pharmacological inhibition of SRC-1 phase separation suppresses YAP oncogenic transcription activity

Zhu, G., Xie, J., Fu, Z., Wang, M., Zhang, Q., He, H., Chen, Z., Guo, X., & Zhu, J. (2021) · Cell Research · doi:10.1038/s41422-021-00504-x · Cited by 63