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Social Transmission of Fear in Rats: The Role of 22-kHz Ultrasonic Distress Vocalization
Open accessAbstract
BACKGROUND: Social alarm calls alert animals to potential danger and thereby promote group survival. Adult laboratory rats in distress emit 22-kHz ultrasonic vocalization (USV) calls, but the question of whether these USV calls directly elicit defensive behavior in conspecifics is unresolved. METHODOLOGY/PRINCIPAL FINDINGS: The present study investigated, in pair-housed male rats, whether and how the conditioned fear-induced 22-kHz USVs emitted by the 'sender' animal affect the behavior of its partner, the 'receiver' animal, when both are placed together in a novel chamber. The sender rats' conditioned fear responses evoked significant freezing (an overt evidence of fear) in receiver rats that had previously experienced an aversive event but not in naïve receiver rats. Permanent lesions and reversible inactivations of the medial geniculate nucleus (MGN) of the thalamus effectively blocked the receivers' freeezing response to the senders' conditioned fear responses, and this occurred in absence of lesions/inactivations impeding the receiver animals' ability to freeze and emit 22-kHz USVs to the aversive event per se. CONCLUSIONS/SIGNIFICANCE: These results--that prior experience of fear and intact auditory system are required for receiver rats to respond to their conspecifics' conditioned fear responses--indicate that the 22-kHz USV is the main factor for social transmission of fear and that learning plays a crucial role in the development of social signaling of danger by USVs.
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“Observer mice did not have experience with foot-shock (i.e., “priming”) prior to demonstrator conditioning (cf. 7–9).”
From Oxytocin enhances observational fear in mice (2017) · cites this paper as [8]
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Cites
Rescorla, R. A. (1972) · Medical Entomology and Zoology · Cited by 7,268
Hölldobler, B., & Wilson, E. O. (1990) · Springer eBooks · doi:10.1007/978-3-662-10306-7 · Cited by 5,476
Crouching as an index of fear.
Blanchard, R. J., & Blanchard, D. C. (1969) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0026779 · Cited by 1,077
Antipredator defensive behaviors in a visible burrow system
Blanchard, R. J., & Blanchard, D. C. (1989) · Journal of comparative psychology · doi:10.1037/0735-7036.103.1.70 · Cited by 663
Olsson, A., & Phelps, E. A. (2007) · Nature Neuroscience · doi:10.1038/nn1968 · Cited by 622
Ultrasonic vocalizations as indices of affective states in rats
Knutson, B., Burgdorf, J., & Panksepp, J. (2002) · Psychological Bulletin · doi:10.1037/0033-2909.128.6.961 · Cited by 618
Romanski, L. M., & LeDoux, J. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-11-04501.1992 · Cited by 470
Precise auditory–vocal mirroring in neurons for learned vocal communication
Prather, J. F., Peters, S., Nowicki, S., & Mooney, R. (2008) · Nature · doi:10.1038/nature06492 · Cited by 463 · cited 1×
“Obviously, manipulations that can selectively inhibit USVs without altering other postshock fear responses (currently unavailable) will be required to further test this notion of auto-conditioning, perhaps analogous to auditory mirroring hypothesized in birds [40].”
BackgroundBlanchard, R. J., Blanchard, D. C., Agullana, R., & Weiss, S. M. (1991) · Physiology & Behavior · doi:10.1016/0031-9384(91)90423-l · Cited by 461
Goldstein, L. E., Rasmusson, A. M., Bunney, B. S., & Roth, R. H. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-15-04787.1996 · Cited by 387
Kim, J. J., DeCola, J. P., Landeira-Fernández, J., & Fanselow, M. S. (1991) · Behavioral Neuroscience · doi:10.1037/0735-7044.105.1.126 · Cited by 301
Self-citationInactivation of the Interoceptive Insula Disrupts Drug Craving and Malaise Induced by Lithium
Contreras, M., Ceric, F., & Torrealba, F. (2007) · Science · doi:10.1126/science.1145590 · Cited by 297
Rat 22kHz ultrasonic vocalizations as alarm cries
Litvin, Y., Blanchard, D. C., & Blanchard, R. J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.11.038 · Cited by 242
Amygdalar NMDA Receptors Are Critical for the Expression of Multiple Conditioned Fear Responses
Lee, H. J., Choi, J.-S., Brown, T. H., & Kim, J. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-11-04116.2001 · Cited by 197
Self-citationEthology: The Mechanisms and Evolution of Behavior
Gould, J. L. (1982) · Medical Entomology and Zoology · Cited by 193
Kim, J. J., Koo, J. W., Lee, H. J., & Han, J.-S. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.4623-04.2005 · Cited by 184
Self-citationBorta, A., Wöhr, M., & Schwarting, R. K. W. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.08.009 · Cited by 173
Sadananda, M., Wöhr, M., & Schwarting, R. K. W. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.02.002 · Cited by 169
Social modulation of learning in ratsPreprint
Knapska, E., Mikosz, M., Werka, T., & Maren, S. (2009) · Learning & Memory · doi:10.1101/lm.1670910 · Cited by 162
Behavioural responses of laboratory rats to playback of 22 kHz ultrasonic calls
Brudzyński, S. M., & Chiu, E. M. C. (1995) · Physiology & Behavior · doi:10.1016/0031-9384(95)00003-2 · Cited by 159
Howland, J. G., Taepavarapruk, P., & Phillips, A. G. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-03-01137.2002 · Cited by 155
Odors released by stressed rats produce opioid analgesia in unstressed rats.
Fanselow, M. S. (1985) · Behavioral Neuroscience · doi:10.1037//0735-7044.99.3.589 · Cited by 152
The medial geniculate, not the amygdala, as the root of auditory fear conditioning
Weinberger, N. M. (2010) · Hearing Research · doi:10.1016/j.heares.2010.03.093 · Cited by 148
Odors released by stressed rats produce opioid analgesia in unstressed rats.
Fanselow, M. S. (1985) · Behavioral Neuroscience · doi:10.1037/0735-7044.99.3.589 · Cited by 138
Fear conditioning by-proxy: Social transmission of fear during memory retrieval
Bruchey, A. K., Jones, C. E., & Monfils, M.-H. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.04.047 · Cited by 128
The Production of Ultrasonic Sounds by Laboratory Rats and Other Mammals
Anderson, J. W. (1954) · Science · doi:10.1126/science.119.3101.808 · Cited by 118
van der Poel, A. M., & Miczek, K. A. (1991) · Behaviour · doi:10.1163/156853991x00409 · Cited by 112
Choi, J.-S., & Brown, T. H. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08713.2003 · Cited by 107
A thalamo‐cortico‐amygdala pathway mediates auditory fear conditioning in the intact brain
Boatman, J. A., & Kim, J. J. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04965.x · Cited by 104
Self-citationCentral C-Fos Expression Following 20kHz/Ultrasound Induced Defence Behaviour in the Rat
Beckett, S. R. G., Duxon, M. S., Aspley, S., & Marsden, C. A. (1997) · Brain Research Bulletin · doi:10.1016/s0361-9230(96)00332-2 · Cited by 96
Perirhinal Cortex Supports Delay Fear Conditioning to Rat Ultrasonic Social Signals
Lindquist, D. H., Jarrard, L. E., & Brown, T. H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4839-03.2004 · Cited by 95
Cruikshank, S. J., Edeline, J., & Weinberger, N. M. (1992) · Behavioral Neuroscience · doi:10.1037//0735-7044.106.3.471 · Cited by 92
Language and Animal Communication: Parallels and Contrasts
(1995) · The MIT Press eBooks · doi:10.7551/mitpress/1975.003.0022 · Cited by 88
Are rats predisposed to learn 22kHz calls as danger-predicting signals?
Endres, T., Widmann, K., & Fendt, M. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.07.012 · Cited by 78
The effect of 22 kHz calls and artificial 38 kHz signals on activity in rats
Sales, G. (1991) · Behavioural Processes · doi:10.1016/0376-6357(91)90001-g · Cited by 77
Cruikshank, S. J., Edeline, J., & Weinberger, N. M. (1992) · Behavioral Neuroscience · doi:10.1037/0735-7044.106.3.471 · Cited by 76
Seyfarth, R. M., & Cheney, D. L. (1992) · Scientific American · doi:10.1038/scientificamerican1292-122 · Cited by 75
Social modulation of associative fear learning by pheromone communicationPreprint
Bredy, T. W., & Barad, M. (2008) · Learning & Memory · doi:10.1101/lm.1226009 · Cited by 68
Ultrasonic calling during fear conditioning in the rat: no evidence for an audience effect
Wöhr, M., & Schwarting, R. K. W. (2008) · Animal Behaviour · doi:10.1016/j.anbehav.2008.04.017 · Cited by 59
Graham, L. K., Yoon, T., Lee, H. J., & Kim, J. J. (2009) · Psychology & Neuroscience · doi:10.3922/j.psns.2009.2.015 · Cited by 55
Self-citationComparison between cholinergically and naturally induced ultrasonic vocalization in the rat.
Brudzyński, S. M., Ociepa, D., & Bihari, F. (1991) · PubMed · Cited by 43
Single-unit responses to 22kHz ultrasonic vocalizations in rat perirhinal cortex
Allen, T. A., Furtak, S. C., & Brown, T. H. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.03.009 · Cited by 43
Social Transmission of Avoidance Behavior under Situational Change in Learned and Unlearned Rats
Masuda, A., & Aou, S. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006794 · Cited by 33
Song (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00024 · Cited by 16
13. Four Months of the Ground Squirrel
Sherman, P. W., & Morton, M. L. (1987) · Columbia University Press eBooks · doi:10.7312/topo93832-016 · Cited by 5
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Burkett, J. P., Andari, E., Johnson, Z. V., Curry, D. C., de Waal, F. B. M., & Young, L. J. (2016) · Science · doi:10.1126/science.aac4785 · Cited by 692
Ethotransmission: communication of emotional states through ultrasonic vocalization in rats.
Brudzynski, S. M. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.01.014 · Cited by 416
Wöhr, M., & Schwarting, R. K. W. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1607-9 · Cited by 371
Toward a cross-species understanding of empathy
Panksepp, J., & Panksepp, J. B. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.04.009 · Cited by 309
Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning
Allsop, S. A., Wichmann, R., Mills, F., Burgos-Robles, A., Chang, C.-J., Felix-Ortiz, A. C., Vienne, A., Beyeler, A., Izadmehr, E. M., Glober, G., et al. (2018) · Cell · doi:10.1016/j.cell.2018.04.004 · Cited by 288
Metadata
- Authors
- Kim, E. J., Kim, E. S., Covey, E., & Kim, J. J.
- Affiliations
- University of Washington (US)
- Corresponding author
- Kim, Jeansok J.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2010-12-01
- Volume
- 5
- Issue
- 12
- Pages
- e15077
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC2995742
- OpenAlex
- W1982780621
- Cited by
- 216
- References
- 44
- Citations by year
- 2026: 11 · 2025: 14 · 2024: 13 · 2023: 18 · 2022: 10 · 2021: 14 · 2020: 13 · 2019: 17 · 2018: 27 · 2017: 15 · 2016: 18 · 2015: 10 · 2014: 6 · 2013: 16 · 2012: 9
- FWCI
- 6.59
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Digital Commons - George Fox University (George Fox University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Funders
- National Institute of Mental Health (MH64457, R01 MH64457, R01MH064457)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Vocal Communication and Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Primate Behavior and Ecology
- Keywords
- distress vocalizations, fear conditioning, freezing behavior, medial geniculate body, thalamus, conspecific communication, rats
- MeSH terms
- Anesthetics, Local, Animals, Animal Communication, Behavior, Animal, Conditioning, Classical, Fear, Freezing, Geniculate Bodies, Lidocaine, Male, Social Behavior, Thalamus, Ultrasonics, Vocalization, Animal, Rats
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