Amygdalar Inactivation Blocks Stress-Induced Impairments in Hippocampal Long-Term Potentiation and Spatial Memory

Kim, Jeansok J.; Koo, Ja Wook; Lee, Hongjoo J.; Han, Jung-Soo

doi:10.1523/jneurosci.4623-04.2005

Cited by 184Memory and Neural MechanismsStress Responses and CortisolNeuroscience and Neuropharmacology Research

Amygdalar Inactivation Blocks Stress-Induced Impairments in Hippocampal Long-Term Potentiation and Spatial Memory

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Kim, Jeansok J., Koo, Ja Wook, Lee, Hongjoo J., Han, Jung-Soo·2005·The Journal of Neuroscience

DOI 10.1523/jneurosci.4623-04.2005PMC PMC6725997

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Abstract

Electrolytic lesions to the amygdala, a limbic structure implicated in stress-related behaviors and memory modulation, have been shown to prevent stress-induced impairments of hippocampal long-term potentiation (LTP) and spatial memory in rats. The present study investigated the role of intrinsic amygdalar neurons in mediating stress effects on the hippocampus by microinfusing the GABA(A) receptor agonist muscimol into the amygdala and examining stress effects on Schaffer collateral/commissural-CA1 LTP and spatial memory. The critical period of the amygdalar contribution to stress effects on hippocampal functions was determined by applying muscimol either before stress or immediately after stress. Our results indicate that intra-amygdalar muscimol infusions before uncontrollable restraint-tailshock stress effectively blocked stress-induced physiological and behavioral effects. Specifically, hippocampal slices prepared from vehicle-infused stressed animals exhibited markedly impaired LTP, whereas slices obtained from muscimol-infused stressed animals demonstrated robust LTP comparable with that of unstressed animals. Correspondingly, vehicle-infused stressed animals displayed impaired spatial memory (on a hidden platform version of the Morris water maze task), whereas muscimol-infused stressed animals revealed unimpaired spatial memory. In contrast to prestress muscimol effects, however, immediate poststress infusions of muscimol into the amygdala failed to interfere with stress impairments of LTP and spatial memory. Together, these results suggest that the amygdalar neuronal activity during stress, but not shortly after stress, is essential for the emergence of stress-induced alterations in hippocampal LTP and memory.

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Damage to, or inactivation of, the amygdala blocks stress effects on hippocampal LTP and spatial memory.
“damage to, or inactivation of, the amygdala blocks stress effects on hippocampal LTP and spatial memory (Almaguer-Melian et al. [214]; Kim et al. [154]; Korz and Frey [215]; Kim and Jung [21]).”
From The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007) · cites this paper as Kim et al. [154]
A strong stressor generates a powerful inhibitory influence on hippocampal memory processing for events occurring 30-60 minutes after the onset of a stressful experience.
“Overall, these findings, in conjunction with related work by Kim et al. [154] support our hypothesis that a strong stressor generates a powerful inhibitory influence on hippocampal memory processing for events occurring 30–60 minutes after the onset of a stressful experience.”
From The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007) · cites this paper as Kim et al. [154]

Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path
Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,460 · see citing works
LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
Scoville, W. B., & Milner, B. (1957) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.20.1.11 · Cited by 7,322 · see citing works
The Organization of Behavior; A Neuropsychological Theory.
Attneave, F., B., M., & Hebb, D. O. (1950) · The American Journal of Psychology · doi:10.2307/1418888 · Cited by 5,146 · see citing works
Memory - A century of consolidation
McGaugh, J. L. (2000) · Science · doi:10.1126/science.287.5451.248 · Cited by 4,250 · see citing works
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
Morris, R. G. M., Anderson, E., Lynch, G. S., & Baudry, M. (1986) · Nature · doi:10.1038/319774a0 · Cited by 3,640 · see citing works
Long-Term Potentiation--A Decade of Progress?
Malenka, R. C., & Nicoll, A. R. A. (1999) · Science · doi:10.1126/science.285.5435.1870 · Cited by 2,729 · see citing works
Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation
REUL, J. M. H. M., & KLOET, E. R. D. (1985) · Endocrinology · doi:10.1210/endo-117-6-2505 · Cited by 2,580 · see citing works
Learned helplessness: Theory and evidence
Maier, S. F., & Seligman, M. E. (1976) · Journal of Experimental Psychology: General · doi:10.1037/0096-3445.105.1.3 · Cited by 2,494 · see citing works
Failure to escape traumatic shock.
Seligman, M. E., & Maier, S. F. (1967) · Journal of Experimental Psychology · doi:10.1037/h0024514 · Cited by 1,981 · see citing works
Stress and cognitive function
McEwen, B. S., & Sapolsky, R. M. (1995) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(95)80028-x · Cited by 1,889 · see citing works
Mechanisms of emotional arousal and lasting declarative memory.
Cahill, L., & McGaugh, J. L. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01214-9 · Cited by 1,575 · see citing works
The stressed hippocampus, synaptic plasticity and lost memories
Kim, J. J., & Diamond, D. M. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn849 · Cited by 1,543 · see citing works
Self-citation
Structure and function of declarative and nondeclarative memory systems
Squire, L. R., & Zola, S. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13515 · Cited by 1,327 · see citing works
Stress and glucocorticoids impair retrieval of long-term spatial memory
de Quervain, D. J.-F., Roozendaal, B., & McGaugh, J. L. (1998) · Nature · doi:10.1038/29542 · Cited by 1,182 · see citing works
The hippocampus—what does it do?
Eichenbaum, H., Otto, T., & Cohen, N. J. (1992) · Behavioral and Neural Biology · doi:10.1016/0163-1047(92)90724-i · Cited by 867 · see citing works
Untitled work
(1992) · Cited by 777 · see citing works
Inverted-U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation
Diamond, D. M., Bennett, M. C., Fleshner, M., & Rose, G. M. (1992) · Hippocampus · doi:10.1002/hipo.450020409 · Cited by 688 · see citing works
Effects of adverse experiences for brain structure and function
McEwen, B. S. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00964-1 · Cited by 639 · see citing works
Amygdala modulation of hippocampal-dependent and caudate nucleus-dependent memory processes
Packard, M. G., Cahill, L., & McGaugh, J. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.18.8477 · Cited by 544 · see citing works
Amygdala is critical for stress-induced modulation of hippocampal long-term potentiation and learning
Kim, J. J., Lee, H. J., Han, J.-S., & Packard, M. G. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05222.2001 · Cited by 537 · see citing works
Self-citation
Projections from the amygdaloid complex and adjacent olfactory structures to the entorhinal cortex and to the subiculum in the rat and cat
Krettek, J. E., & Price, J. L. (1977) · The Journal of Comparative Neurology · doi:10.1002/cne.901720409 · Cited by 535 · see citing works
Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats
Bodnoff, S., Humphreys, A., Lehman, J., Diamond, D. M., Rose, G., & Meaney, M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00061.1995 · Cited by 522 · see citing works
Localization of a Memory Trace in the Mammalian Brain
Krupa, D. J., Thompson, J. K., & Thompson, R. F. (1993) · Science · doi:10.1126/science.8493536 · Cited by 515 · see citing works
Behavioural stress facilitates the induction of long-term depression in the hippocampus
Xu, L., Anwyl, R., & Rowan, M. J. (1997) · Nature · doi:10.1038/387497a0 · Cited by 509 · see citing works
Twenty-two kHz alarm cries to presentation of a predator, by laboratory rats living in visible burrow systems
Blanchard, R. J., Blanchard, D. C., Agullana, R., & Weiss, S. M. (1991) · Physiology & Behavior · doi:10.1016/0031-9384(91)90423-l · Cited by 461 · see citing works
Inescapable versus escapable shock modulates long-term potentiation in the rat hippocampus
Shors, T. J., Seib, T. B., Levine, S., & Thompson, R. F. (1989) · Science · doi:10.1126/science.2704997 · Cited by 458 · see citing works
Principles of Neuropsychopharmacology
Feldman, R. S., Meyer, J. S., & Quenzer, L. F. (1997) · Cited by 437 · see citing works
Behavioral stress impairs long-term potentiation in rodent hippocampus
Foy, M. R., Stanton, M. E., Levine, S., & Thompson, R. F. (1987) · Behavioral and Neural Biology · doi:10.1016/s0163-1047(87)90664-9 · Cited by 436 · see citing works
Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation.
Kim, J. J., Foy, M. R., & Thompson, R. F. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.10.4750 · Cited by 435 · see citing works
Self-citation
Stress: metaplastic effects in the hippocampus
Kim, J. J., & Yoon, K. S. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01322-8 · Cited by 403 · see citing works
Self-citation
Mind and body; The theories of their relation.
Bain, A. (1877) · D. Appleton and company eBooks · doi:10.1037/12850-000 · Cited by 393 · see citing works
Role of the amygdala in the coordination of behavioral, neuroendocrine, and prefrontal cortical monoamine responses to psychological stress in the rat
Goldstein, L. E., Rasmusson, A. M., Bunney, B. S., & Roth, R. H. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-15-04787.1996 · Cited by 387 · see citing works
Functional inactivation of the lateral and basal nuclei of the amygdala by muscimol infusion prevents fear conditioning to an explicit conditioned stimulus and to contextual stimuli.
Muller, J., Corodimas, K. P., Fridel, Z., & LeDoux, J. E. (1997) · Behavioral Neuroscience · doi:10.1037/0735-7044.111.4.683 · Cited by 382 · see citing works
Functional inactivation of the lateral and basal nuclei of the amygdala by muscimol infusion prevents fear conditioning to an explicit conditioned stimulus and to contextual stimuli.
Muller, J., Corodimas, K. P., Fridel, Z., & LeDoux, J. E. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.4.683 · Cited by 382 · see citing works
Effects of glucocorticoids and norepinephrine on the excitability in the hippocampus
Joëls, M., & de Kloet, E. R. (1989) · Science · doi:10.1126/science.2781292 · Cited by 375 · see citing works
Yeast and apoptosis
Jin, C., & Reed, J. C. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm832 · Cited by 340 · see citing works
The hippocampus mediates glucocorticoid-induced impairment of spatial memory retrieval: Dependence on the basolateral amygdala
Roozendaal, B., Griffith, Q. K., Buranday, J., de Quervain, D. J.-F., & McGaugh, J. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337480100 · Cited by 291 · see citing works
Exposing Rats to a Predator Blocks Primed Burst Potentiation in the Hippocampus<i>In Vitro</i>
Mesches, M. H., Fleshner, M., Heman, K. L., Rose, G. M., & Diamond, D. M. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-14-j0004.1999 · Cited by 276 · see citing works
Corticosteroid Modulation of Hippocampal Potentials: Increased Effect with Aging
Kerr, D. S., Campbell, L. W., Hao, S.-Y., & Landfield, P. W. (1989) · Science · doi:10.1126/science.2781293 · Cited by 271 · see citing works
Effects of muscimol applied to the basolateral amygdala on acquisition and expression of contextual fear conditioning in rats.
Helmstetter, F. J., & Bellgowan, P. S. F. (1994) · Behavioral Neuroscience · doi:10.1037//0735-7044.108.5.1005 · Cited by 265 · see citing works
Biphasic Modulation of Hippocampal Plasticity by Behavioral Stress and Basolateral Amygdala Stimulation in the Rat
Akirav, I., & Richter-Levin, G. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-23-10530.1999 · Cited by 250 · see citing works
Long-term potentiation and memory
Morris, R. G. M. (2003) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1230 · Cited by 232 · see citing works
Functional Inactivation of the Amygdala before But Not after Auditory Fear Conditioning Prevents Memory Formation
Wilensky, A. E., Schafe, G. E., & LeDoux, J. E. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-24-j0006.1999 · Cited by 217 · see citing works
The amygdala is essential for the expression of conditional hypoalgesia.
Helmstetter, F. J. (1992) · Behavioral Neuroscience · doi:10.1037//0735-7044.106.3.518 · Cited by 203 · see citing works
Stress Impairs LTP and Hippocampal‐Dependent Memorya
Diamond, D. M., & ROSE, G. M. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb39271.x · Cited by 195 · see citing works
Amygdalar NMDA Receptors Are Critical for the Expression of Multiple Conditioned Fear Responses
Lee, H. J., Choi, J.-S., Brown, T. H., & Kim, J. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-11-04116.2001 · Cited by 195 · see citing works
Self-citation
Basolateral Amygdala Is Involved in Modulating Consolidation of Memory for Classical Fear Conditioning
Vazdarjanova, A., & McGaugh, J. D. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-15-06615.1999 · Cited by 194 · see citing works
Brain slice preparation: Hippocampus
Teyler, T. J. (1980) · Brain Research Bulletin · doi:10.1016/s0361-9230(80)80009-8 · Cited by 192 · see citing works
The Amygdala Is Essential for the Development of Neuronal Plasticity in the Medial Geniculate Nucleus during Auditory Fear Conditioning in Rats
Maren, S., Yap, S. A., & Goosens, K. A. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-06-j0001.2001 · Cited by 186 · see citing works
In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus
Pittenger, C., & Kandel, E. R. (2003) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1247 · Cited by 174 · see citing works
Behavioural responses of laboratory rats to playback of 22 kHz ultrasonic calls
Brudzyński, S. M., & Chiu, E. M. C. (1995) · Physiology & Behavior · doi:10.1016/0031-9384(95)00003-2 · Cited by 159 · see citing works
A description of the amygdalo-hippocampal interconnections in the macaque monkey
Aggleton, J. P. (1986) · Experimental Brain Research · doi:10.1007/bf00340489 · Cited by 155 · see citing works
Attenuated hippocampal long-term potentiation in basolateral amygdala-lesioned rats
Ikegaya, Y., Saitō, H., & Abe, K. (1994) · Brain Research · doi:10.1016/0006-8993(94)91377-3 · Cited by 142 · see citing works
Unilateral Block of NMDA Receptors in the Amygdala Prevents Predator Stress-Induced Lasting Increases in Anxiety-Like Behavior and Unconditioned Startle—Effective Hemisphere Depends on the Behavior
Adamec, R. E., Burton, P., Shallow, T., & Budgell, J. (1998) · Physiology & Behavior · doi:10.1016/s0031-9384(98)00225-x · Cited by 137 · see citing works
The Production of Ultrasonic Sounds by Laboratory Rats and Other Mammals
Anderson, J. W. (1954) · Science · doi:10.1126/science.119.3101.808 · Cited by 118 · see citing works
Long Ultrasonic Calls in Male Rats Following Mating, Defeat and Aversive Stimulation: Frequency Modulation and Bout Structure
van der Poel, A. M., & Miczek, K. A. (1991) · Behaviour · doi:10.1163/156853991x00409 · Cited by 112 · see citing works
Effects of stress and long-term potentiation (LTP) on subsequent LTP and the theta burst response in the dentate gyrus
Shors, T. J., & Dryver, E. T. (1994) · Brain Research · doi:10.1016/0006-8993(94)90777-3 · Cited by 111 · see citing works
Modulation of Hippocampal Long-Term Potentiation by the Amygdala: A Synaptic Mechanism Linking Emotion and Memory
Abe, K. (2001) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.86.18 · Cited by 106 · see citing works
The Basomedial and Basolateral Amygdaloid Nuclei Contribute to the Induction of Long‐term Potentiation in the Dentate Gyrus In Vivo
Ikegaya, Y., Saitō, H., & Abe, K. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01327.x · Cited by 105 · see citing works
A method to measure the effective spread of focally injected muscimol into the central nervous system with electrophysiology and light microscopy
Arikan, R., Blake, N. M. J., Erinjeri, J. P., Woolsey, T. A., Giraud, L., & Highstein, S. M. (2002) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(02)00143-7 · Cited by 99 · see citing works
Startle-inducing acoustic stimuli evoke ultrasonic vocalization in the rat
Kaltwasser, M.-T. (1990) · Physiology & Behavior · doi:10.1016/0031-9384(90)90253-z · Cited by 98 · see citing works
Effect of Adrenalectomy and Demedullation on the Stress-Induced Impairment of Long-Term Potentiation
Shors, T. J., Levine, S., & Thompson, R. F. (2008) · Neuroendocrinology · doi:10.1159/000125318 · Cited by 87 · see citing works
Time-dependent blockade of STP and LTP in hippocampal slices following acute stress in mice
Garcia, R., Musleh, W., Tocco, G., Thompson, R. F., & Baudry, M. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00621-6 · Cited by 83 · see citing works
Ultrasonic vocalization induced by intracerebral carbachol in rats: Localization and a dose-response study
Brudzyński, S. M. (1994) · Behavioural Brain Research · doi:10.1016/0166-4328(94)90084-1 · Cited by 77 · see citing works
Basolateral amygdala lesions block the disruptive effects of long-term adrenalectomy on spatial memory
Roozendaal, B., Sapolsky, R. M., & McGaugh, J. L. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00538-1 · Cited by 56 · see citing works
Quinpirole and d-amphetamine administration posttraining enhances memory on spatial and cued discriminations in a water maze
Packard, M. G., & McGaugh, J. L. (1994) · Psychobiology · doi:10.3758/bf03327080 · Cited by 51 · see citing works
Amygdaloid lesions attenuate neurogenic gastric mucosal erosions but do not alter gastric secretory changes induced by intracisternal bombesin
Grijalva, C. V., Taché, Y., Gunion, M. W., Walsht, J. H., & Geiselman, P. J. (1986) · Brain Research Bulletin · doi:10.1016/0361-9230(86)90012-2 · Cited by 36 · see citing works
Bain on Neural Networks
Wilkes, A. L., & Wade, N. J. (1997) · Brain and Cognition · doi:10.1006/brcg.1997.0869 · Cited by 35 · see citing works
Attenuation of shock-induced ulcers after lesions in the medial amygdala☆
Henke, P. G. (1981) · Physiology & Behavior · doi:10.1016/0031-9384(81)90311-5 · Cited by 34 · see citing works
Amygdala N-methyl-d-aspartate receptors participate in the induction of long-term potentiation in the dentate gyrus in vivo
Ikegaya, Y., Saitō, H., & Abe, K. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)11643-b · Cited by 29 · see citing works
Untitled work
Merchenthaler (1999) · doi:10.1002/(sici)1096-9861(19990111)403:2
Untitled work
(1997) · doi:10.1002/(sici)1098-2396(199707)26:3

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McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 4,981 · see citing works
Stress, memory and the amygdala
Roozendaal, B., McEwen, B. S., & Chattarji, S. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2651 · Cited by 1,760 · see citing works
The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course
McEwen, B. S., & Morrison, J. H. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.028 · Cited by 1,079 · see citing works
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Diamond, D. M., Campbell, A. M., Park, C. R., Halonen, J., & Zoladz, P. R. (2007) · Neural Plasticity · doi:10.1155/2007/60803 · Cited by 762 · see citing works
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Stress and Memory: Behavioral Effects and Neurobiological Mechanisms
Sandi, C., & Pinelo-Nava, M. T. (2007) · Neural Plasticity · doi:10.1155/2007/78970 · Cited by 611 · see citing works
Stress and anxiety: Structural plasticity and epigenetic regulation as a consequence of stress
McEwen, B. S., Eiland, L., Hunter, R. G., & Miller, M. M. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.07.014 · Cited by 596 · see citing works
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Mitra, R., & Sapolsky, R. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705615105 · Cited by 409 · see citing works
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Self-citation
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Hippocampal long-term depression mediates spatial reversal learning in the Morris water maze
Dong, Z., Bai, Y., Wu, X., Li, H., Gong, B., Howland, J. G., Huang, Y., He, W., Li, T., & Wang, Y. T. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.06.027 · Cited by 219 · see citing works
Hippocampal long-term depression mediates acute stress-induced spatial memory retrieval impairment
Wong, T. P., Howland, J. G., Robillard, J. M., Ge, Y., Yu, W. K., Titterness, A. K., Brebner, K., Liu, L., Weinberg, J., Christie, B. R., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702308104 · Cited by 218 · see citing works
Social Transmission of Fear in Rats: The Role of 22-kHz Ultrasonic Distress Vocalization
Kim, E. J., Kim, E. S., Covey, E., & Kim, J. J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015077 · Cited by 216 · see citing works
Self-citation
Acute predator stress impairs the consolidation and retrieval of hippocampus-dependent memory in male and female ratsPreprint
Park, C. R., Zoladz, P. R., Conrad, C. D., Fleshner, M., & Diamond, D. M. (2008) · Learning & Memory · doi:10.1101/lm.721108 · Cited by 170 · see citing works
Stress Impairs 5-HT2A Receptor-Mediated Serotonergic Facilitation of GABA Release in Juvenile Rat Basolateral Amygdala
Jiang, X., Xing, G., Yang, C., Verma, A. M., Zhang, L., & Li, H. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.71 · Cited by 143 · see citing works
LTP after Stress: Up or Down?
Joëls, M., & Krugers, H. J. (2007) · Neural Plasticity · doi:10.1155/2007/93202 · Cited by 138 · see citing works
Modulation of stress consequences by hippocampal monoaminergic, glutamatergic and nitrergic neurotransmitter systems
Joca, S. R. L., Ferreira, F. R., & Guimarães, F. S. (2007) · Stress · doi:10.1080/10253890701223130 · Cited by 137 · see citing works
Stress-induced metaplasticity: From synapses to behavior
Schmidt, M. V., Abraham, W. C., Maroun, M., Stork, O., & Richter‐Levin, G. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.06.059 · Cited by 134 · see citing works
Object recognition and Morris water maze to detect cognitive impairment from mild hippocampal damage in rats: A reflection based on the literature and experience
Lissner, L. J., Wartchow, K. M., Toniazzo, A. P., Gonçalves, C., & Rodrigues, L. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173273 · Cited by 133 · see citing works
Amygdala and bed nucleus of the stria terminalis circuitry: Implications for addiction-related behaviors
Stamatakis, A. M., Sparta, D. R., Jennings, J. H., McElligott, Z. A., Decot, H., & Stuber, G. D. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.05.046 · Cited by 132 · see citing works
Competitive interactions between endogenous LTD and LTP in the hippocampus underlie the storage of emotional memories and stress‐induced amnesia
Diamond, D., Park, C. R., Campbell, A. M., & Woodson, J. C. (2005) · Hippocampus · doi:10.1002/hipo.20107 · Cited by 128 · see citing works
Neurocognitive effects of stress: a metaparadigm perspective
Kim, E. J., & Kim, J. J. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-01986-4 · Cited by 136 · see citing works
Self-citation
Stress-induced alterations in hippocampal plasticity, place cells, and spatial memory
Kim, J. J., Lee, H. J., Welday, A. C., Song, E., Cho, J., Sharp, P. E., Jung, M. W., & Blair, H. T. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708644104 · Cited by 119 · see citing works
Self-citation
Analysis of the Stress Response in Rats Trained in the Water-Maze: Differential Expression of Corticotropin-Releasing Hormone, CRH-R1, Glucocorticoid Receptors and Brain-Derived Neurotrophic Factor in Limbic Regions
Aguilar‐Valles, A., Sánchez, E., de Gortari, P., Balderas, I., Ramı́rez-Amaya, V., Bermúdez‐Rattoni, F., & Joseph‐Bravo, P. (2005) · Neuroendocrinology · doi:10.1159/000093129 · Cited by 121 · see citing works
Oxytocin Protects Hippocampal Memory and Plasticity from Uncontrollable Stress
Lee, S.-Y., Park, S.-H., Chung, C., Kim, J. J., Choi, S.-Y., & Han, J.-S. (2015) · Scientific Reports · doi:10.1038/srep18540 · Cited by 119 · see citing works
Self-citation
Functional Connectivity from the Amygdala to the Hippocampus Grows Stronger after Stress
Ghosh, S., Laxmi, T. R., & Chattarji, S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0638-13.2013 · Cited by 107 · see citing works
Prenatal exposure to noise stress: Anxiety, impaired spatial memory, and deteriorated hippocampal plasticity in postnatal life
Barzegar, M., Sajjadi, F. S., Talaei, S. A., Hamidi, G. A., & Salami, M. (2014) · Hippocampus · doi:10.1002/hipo.22363 · Cited by 108 · see citing works
Amygdala-hippocampal interactions in synaptic plasticity and memory formation
Roesler, R., Parent, M. B., LaLumiere, R. T., & McIntyre, C. K. (2021) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2021.107490 · Cited by 108 · see citing works
Effects of stress and corticosterone on activity and plasticity in the amygdala
Kavushansky, A., & Richter‐Levin, G. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.21058 · Cited by 106 · see citing works
Establishing an Agenda for Translational Research on PTSD
MILLER, M. M., & McEWEN, B. S. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.023 · Cited by 101 · see citing works
Emotional tagging--a simple hypothesis in a complex reality.
Bergado, J., Lucas, M., & Richter-Levin, G. (2011) · Progress in neurobiology · doi:10.1016/j.pneurobio.2011.03.004 · Cited by 85 · see citing works
Pre-learning stress differentially affects long-term memory for emotional words, depending on temporal proximity to the learning experience
Zoladz, P. R., Clark, B., Warnecke, A., Smith, L., Tabar, J., & Talbot, J. N. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.01.016 · Cited by 102 · see citing works
Converging effects of acute stress on spatial and recognition memory in rodents: A review of recent behavioural and pharmacological findings
Cazakoff, B. N., Johnson, K. J., & Howland, J. G. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.04.002 · Cited by 87 · see citing works
Antidepressant-like activity of magnesium in the chronic mild stress model in rats: alterations in the NMDA receptor subunits
Pochwat, B., Szewczyk, B., Sowa-Kućma, M., Siwek, A., Doboszewska, U., Piekoszewski, W., Gruca, P., Papp, M., & Nowak, G. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713001089 · Cited by 83 · see citing works
Effects of stressors in adolescence on learning and memory in rodent models
Green, M. R., & McCormick, C. M. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.09.012 · Cited by 81 · see citing works
Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress‐induced amnesia
Zoladz, P. R., Park, C. R., Halonen, J. D., Salim, S., Alzoubi, K. H., Srivareerat, M., Fleshner, M., Alkadhi, K. A., & Diamond, D. M. (2011) · Hippocampus · doi:10.1002/hipo.20922 · Cited by 79 · see citing works
Critical brain circuits at the intersection between stress and learning
Bangasser, D. A., & Shors, T. J. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.02.002 · Cited by 78 · see citing works
Impact of glucocorticoids on brain function: Relevance for mood disorders
Joëls, M. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.03.004 · Cited by 77 · see citing works
Is all motivation good for learning? Dissociable influences of approach and avoidance motivation in declarative memoryPreprint
Murty, V. P., LaBar, K. S., Hamilton, D. A., & Adcock, R. A. (2011) · Learning & Memory · doi:10.1101/lm.023549.111 · Cited by 77 · see citing works
Amygdala inactivation reverses fear's ability to impair divided attention and make time stand still.
Meck, W. H., & MacDonald, C. J. (2007) · Behavioral Neuroscience · doi:10.1037/0735-7044.121.4.707 · Cited by 76 · see citing works
Glucocorticoid receptors and β-adrenoceptors in basolateral amygdala modulate synaptic plasticity in hippocampal dentate gyrus, but not in area CA1
Vouimba, R., Yaniv, D., & Richter‐Levin, G. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.07.007 · Cited by 70 · see citing works
Exposure to Stressors Facilitates Long-Term Synaptic Potentiation in the Lateral Habenula
Park, H.-Y., Rhee, J., Park, K., Han, J., Malinow, R., & Chung, C. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.2281-16.2017 · Cited by 70 · see citing works
Self-citation
Biphasic ERK1/2 activation in both the hippocampus and amygdala may reveal a system consolidation of contextual fear memory
Trifilieff, P., Calandreau, L., Herry, C., Mons, N. E., & Micheau, J. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.05.004 · Cited by 68 · see citing works
Glucocorticoid Hyper‐ and Hypofunction
Kim, J. J., & Haller, J. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1391.014 · Cited by 66 · see citing works
Self-citation
Activation of phenotypically distinct neuronal subpopulations in the anterior subdivision of the rat basolateral amygdala following acute and repeated stress
Reznikov, L. R., Reagan, L. P., & Fadel, J. R. (2008) · The Journal of Comparative Neurology · doi:10.1002/cne.21687 · Cited by 65 · see citing works
Recovery after chronic stress within spatial reference and working memory domains: correspondence with hippocampal morphology
Hoffman, A. N., Krigbaum, A. M., Ortiz, J. B., Mika, A., Hutchinson, K. M., Bimonte‐Nelson, H. A., & Conrad, C. D. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07820.x · Cited by 63 · see citing works
Permissive Influence of Stress in the Expression of a U-Shaped Relationship between Serum Corticosterone Levels and Spatial Memory Errors in Rats
Park, C. R., Campbell, A. M., Woodson, J. C., Smith, T. P., Fleshner, M., & Diamond, D. M. (2006) · Dose-Response · doi:10.2203/dose-response.004.01.005.park · Cited by 63 · see citing works
Stress-Induced Reinstatement of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity in the Basolateral Amygdala
Nygard, S. K., Hourguettes, N. J., Sobczak, G. G., Carlezon, W. A., & Bruchas, M. R. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0953-16.2016 · Cited by 61 · see citing works
Role of the Amygdala in Antidepressant Effects on Hippocampal Cell Proliferation and Survival and on Depression-like Behavior in the Rat
Castro, J. E., Varea, E., Márquez, C., Cordero, M. I., Poirier, G. L., & Sandi, C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008618 · Cited by 60 · see citing works
Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway
Rei, D., Mason, X. L., Seo, J., Gräff, J., Rudenko, A., Wang, J., Rueda, R., Siegert, S., Cho, S., Canter, R. G., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1415845112 · Cited by 60 · see citing works
c-Jun N-terminal kinases in memory and synaptic plasticity
Sherrin, T., Blank, T., & Todorovic, C. (2011) · Reviews in the Neurosciences · doi:10.1515/rns.2011.032 · Cited by 56 · see citing works
Strain and sex differences in fear conditioning: 22 kHz ultrasonic vocalizations and freezing in rats.
Graham, L. K., Yoon, T., Lee, H. J., & Kim, J. J. (2009) · Psychology & Neuroscience · doi:10.3922/j.psns.2009.2.015 · Cited by 55 · see citing works
Self-citation
The adaptive and maladaptive continuum of stress responses – a hippocampal perspective
Suri, D., & Vaidya, V. A. (2015) · Reviews in the Neurosciences · doi:10.1515/revneuro-2014-0083 · Cited by 58 · see citing works
The Endocannabinoid System and Anxiety
Lisboa, S. F. D. S., Gomes, F. V., Terzian, A. L. B., de Aguiar, D. C., Moreira, F. A., Resstel, L. B. M., & Guimarães, F. S. (2016) · Vitamins and hormones · doi:10.1016/bs.vh.2016.09.006 · Cited by 56 · see citing works
Chewing ameliorates stress-induced suppression of hippocampal long-term potentiation
Ono, Y., Kataoka, T., Miyake, S., Cheng, S., Tachibana, A., Sasaguri, K., & Onozuka, M. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.04.057 · Cited by 53 · see citing works
Effects of stress, corticosterone, and epinephrine administration on learning in place and response tasks
Sadowski, R. N., Jackson, G. R., Wieczorek, L., & Gold, P. E. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.06.027 · Cited by 51 · see citing works
Acute stress throughout the memory cycle: Diverging effects on associative and item memory.
Goldfarb, E. V., Tompary, A., Davachi, L., & Phelps, E. A. (2018) · Journal of Experimental Psychology General · doi:10.1037/xge0000472 · Cited by 51 · see citing works
The dose makes the poison: From glutamate-mediated neurogenesis to neuronal atrophy and depression
Rubio-Casillas, A., & Fernández-Guasti, A. (2016) · Reviews in the Neurosciences · doi:10.1515/revneuro-2015-0066 · Cited by 49 · see citing works
Neuronal localization of the 5-HT2 receptor family in the amygdaloid complex
Bombardi, C. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00068 · Cited by 48 · see citing works
Stress time-dependently influences the acquisition and retrieval of unrelated information by producing a memory of its own
Cadle, C. E., & Zoladz, P. R. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.00910 · Cited by 47 · see citing works
Effects of repeated prenatal glucocorticoid exposure on long‐term potentiation in the juvenile guinea‐pig hippocampus
Setiawan, E., Jackson, M. F., MacDonald, J. F., & Matthews, S. G. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2006.127381 · Cited by 47 · see citing works
Basolateral amygdalar inactivation blocks chronic stress-induced lamina-specific reduction in prefrontal cortex volume and associated anxiety-like behavior
Tripathi, S. J., Chakraborty, S., Srikumar, B. N., Raju, T. R., & Shankaranarayana Rao, B. S. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.07.016 · Cited by 43 · see citing works
Chronic Clomipramine Treatment Reverses Core Symptom of Depression in Subordinate Tree Shrews
Wang, J., Chai, A., Zhou, Q., Lv, L., Wang, L., Yang, Y., & Xu, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080980 · Cited by 45 · see citing works
Amygdala activation and GABAergic gene expression in hippocampal sub-regions at the interplay of stress and spatial learning
Hadad-Ophir, O., Albrecht, A., Stork, O., & Richter‐Levin, G. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00003 · Cited by 45 · see citing works
17β Estradiol increases resilience and improves hippocampal synaptic function in helpless ovariectomized rats
Bredemann, T. M., & McMahon, L. L. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.01.004 · Cited by 43 · see citing works
Do Stress and Long-Term Potentiation Share the Same Molecular Mechanisms?
Huang, C., Yang, C., & Hsu, K. (2005) · Molecular Neurobiology · doi:10.1385/mn:32:3:223 · Cited by 44 · see citing works
Stress impairs optimal behavior in a water foraging choice task in ratsPreprint
Graham, L. K., Yoon, T., & Kim, J. J. (2009) · Learning & Memory · doi:10.1101/lm.1605510 · Cited by 42 · see citing works
Self-citation
Neonatal isolation stress alters bidirectional long-term synaptic plasticity in amygdalo-hippocampal synapses in freely behaving adult rats
Blaise, J. H., Koranda, J. L., Chow, U., Haines, K. E., & Dorward, E. C. (2007) · Brain Research · doi:10.1016/j.brainres.2007.11.049 · Cited by 41 · see citing works
Stress within a Restricted Time Window Selectively Affects the Persistence of Long-Term Memory
Yang, C., Liu, J., Chai, B.-S., Fang, Q., Chai, N., Zhao, L., Xue, Y.-X., Luo, Y., Jian, M., Han, Y., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059075 · Cited by 38 · see citing works
The dynamic impact of repeated stress on the hippocampal spatial map
Tomar, A., Polygalov, D., Chattarji, S., & McHugh, T. J. (2014) · Hippocampus · doi:10.1002/hipo.22348 · Cited by 36 · see citing works
The expression of TRH, its receptors and degrading enzyme is differentially modulated in the rat limbic system during training in the Morris water maze
Aguilar‐Valles, A., Sánchez, E., de Gortari, P., García-Vázquez, A., Ramı́rez-Amaya, V., Bermúdez‐Rattoni, F., & Joseph‐Bravo, P. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2006.09.009 · Cited by 39 · see citing works
Hippocampal structural plasticity accompanies the resulting contextual fear memory following stress and fear conditioningPreprint
Giachero, M., Calfa, G. D., & Molina, V. A. (2013) · Learning & Memory · doi:10.1101/lm.031724.113 · Cited by 40 · see citing works
Influence of Pre-Training Predator Stress on the Expression of c-fos mRNA in the Hippocampus, Amygdala, and Striatum Following Long-Term Spatial Memory Retrieval
VanElzakker, M., Zoladz, P., Thompson, V. M., Park, C. R., Halonen, J. D., Spencer, R. L., & Diamond, D. (2011) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2011.00030 · Cited by 41 · see citing works
Linear and Non-Linear Dose-Response Functions Reveal a Hormetic Relationship between Stress and Learning
Zoladz, P. R., & Diamond, D. M. (2008) · Dose-Response · doi:10.2203/dose-response.08-015.zoladz · Cited by 37 · see citing works
Enhancement of spatial learning by predator odor in mice: Involvement of amygdala and hippocampus
Galliot, E., Vaillant, M. L., Béard, E., Millot, J., & Pourié, G. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.09.011 · Cited by 36 · see citing works
Pre-learning stress that is temporally removed from acquisition exerts sex-specific effects on long-term memory.
Zoladz, P., Warnecke, A. J., Woelke, S., Burke, H. M., Frigo, R. M., Pisansky, J. M., Lyle, S. M., & Talbot, J. N. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2012.12.012 · Cited by 35 · see citing works
Stressful stimuli modulate memory formation in Lymnaea stagnalis
Martens, K., Caigny, P. D., Parvez, K., Amarell, M., Wong, C., & Lukowiak, K. (2006) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2006.10.005 · Cited by 35 · see citing works
Temporal modulation of hippocampal excitatory transmission by corticosteroids and stress
Chaouloff, F., & Groc, L. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.07.004 · Cited by 36 · see citing works
Stimulus intensity-dependent modulations of hippocampal long-term potentiation by basolateral amygdala priming
Li, Z., & Richter‐Levin, G. (2012) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2012.00021 · Cited by 35 · see citing works
Amygdalar Stimulation Produces Alterations on Firing Properties of Hippocampal Place Cells
Kim, E. J., Kim, E. S., Park, M.-J., Cho, J., & Kim, J. J. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1108-12.2012 · Cited by 34 · see citing works
Self-citation
Stress and Glucocorticoid Contributions to Normal and Pathological Aging
Goosens, K. A., & Sapolsky, R. M. (2007) · CRC Press eBooks · doi:10.1201/9781420005523-13 · Cited by 35 · see citing works
Activation pattern of the limbic system following spatial learning under stress
Kogan, I., & Richter‐Levin, G. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06034.x · Cited by 34 · see citing works
Chewing ameliorates stress-induced suppression of spatial memory by increasing glucocorticoid receptor expression in the hippocampus
Miyake, S., Yoshikawa, G., Yamada, K., Sasaguri, K., Yamamoto, T., Onozuka, M., & Sato, S. (2012) · Brain Research · doi:10.1016/j.brainres.2012.01.011 · Cited by 34 · see citing works
Know thy SEFL: Fear sensitization and its relevance to stressor-related disorders
Nishimura, K., Poulos, A. M., Drew, M. R., & Rajbhandari, A. K. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104884 · Cited by 33 · see citing works
Inactivation of basolateral amygdala prevents chronic immobilization stress-induced memory impairment and associated changes in corticosterone levels
Tripathi, S. J., Chakraborty, S., Srikumar, B. N., Raju, T. R., & Rao, B. S. S. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.05.005 · Cited by 34 · see citing works
Early postnatal stress alters extracellular signal‐regulated kinase signaling in the corticolimbic system modulating emotional circuitry in adult rats
Ishikawa, S., Saito, Y., Yanagawa, Y., Otani, S., Hiraide, S., Shimamura, K., Matsumoto, M., & Togashi, H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07921.x · Cited by 33 · see citing works
Canadian Association of Neurosciences Review: Learning at a Snail's Pace
Parvez, K., Rosenegger, D. G., Orr, M. V., Martens, K., & Lukowiak, K. (2006) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100005291 · Cited by 33 · see citing works

Spatial Memory
Kim, J. J., Koo, J. W., Lee, H. J., & Han, J.-S. (2013)
Self-citation
Amygdala is critical for stress-induced modulation of hippocampal long-term potentiation and learning
Kim, J. J., Lee, H. J., Han, J.-S., & Packard, M. G. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05222.2001 · Cited by 537 · see citing works
Self-citation
M (2001) Amygdala is critical for stressinduced modulation of hippocampal long-term potentiation and learning
Kim, J. J., Lee, H. J., Han, J.-S., & Packard, M. G. (2013)
Self-citation
Effects of inescapable stress on LTP in the amygdala versus the dentate gyrus of freely behaving rats
Vouimba, R., Yaniv, D., Diamond, D., & Richter‐Levin, G. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03294.x · Cited by 114 · see citing works
Neurofascin Knock Down in the Basolateral Amygdala Mediates Resilience of Memory and Plasticity in the Dorsal Dentate Gyrus Under Stress
Saha, R., Kriebel, M., Volkmer, H., Richter‐Levin, G., & Albrecht, A. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-0930-2 · Cited by 10 · see citing works

Authors: Kim, J. J., Koo, J. W., Lee, H. J., & Han, J.-S.
Affiliations: University of Washington (US)
Yale University (US)
Johns Hopkins University (US)
ORCID: Kim, Jeansok J.
Koo, Ja Wook
Lee, Hongjoo J.
Han, Jung-Soo
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 2005-02-09
Volume: 25
Issue: 6
Pages: 1532-1539
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.4623-04.2005
PMC: PMC6725997
OpenAlex: W2053502537
Cited by: 184
References: 71
Citations by year: 2026: 2 · 2025: 2 · 2024: 1 · 2023: 2 · 2022: 4 · 2021: 8 · 2020: 3 · 2019: 4 · 2018: 6 · 2017: 6 · 2016: 12 · 2015: 6 · 2014: 14 · 2013: 19 · 2012: 16
FWCI: 7.12
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-sa
creativecommons.org/licenses/by-nc-sa/4.0/ (vor, 181 d)
Locations: Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Whitehall Foundation
National Institute of Mental Health (MH64457, R01MH064457, 1R01 MH64457)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: amygdala, stress, hippocampal long-term potentiation, spatial memory, muscimol, GABAA receptor, stress-induced memory impairment, limbic system
MeSH terms: Amygdala, Animals, Corticosterone, Drug Administration Schedule, Electroshock, Hippocampus, Male, Memory Disorders, Muscimol, Stress, Physiological, Vocalization, Animal, Rats, Sprague-Dawley, Long-Term Potentiation, GABA Agonists, Maze Learning, Rats, GABA-A Receptor Agonists

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Amygdalar Inactivation Blocks Stress-Induced Impairments in Hippocampal Long-Term Potentiation and Spatial Memory

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