NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both In Vitro and In Vivo

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NMDARs Adapt to Neurotoxic HIV Protein Tat Downstream of a GluN2A–Ubiquitin Ligase Signaling Pathway

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Exploring Cross-Talk Between Oxidative Damage and Excitotoxicity and the Effects of Riluzole in the Rat Cortex After Exposure to Methylmercury

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NMDAR-Mediated Hippocampal Neuronal Death is Exacerbated by Activities of ASIC1a

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Glycine confers neuroprotection through microRNA-301a/PTEN signaling

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Memantine, a Low-Affinity NMDA Receptor Antagonist, Protects against Methylmercury-Induced Cytotoxicity of Rat Primary Cultured Cortical Neurons, Involvement of Ca2+ Dyshomeostasis Antagonism, and Indirect Antioxidation Effects

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Isolation, structure elucidation and neuroprotective effects of caffeoylquinic acid derivatives from the roots of Arctium lappa L.

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Icaritin Alleviates Glutamate-Induced Neuronal Damage by Inactivating GluN2B-Containing NMDARs Through the ERK/DAPK1 Pathway

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Bacopa monnieri Extract (CDRI-08) Modulates the NMDA Receptor Subunits and nNOS-Apoptosis Axis in Cerebellum of Hepatic Encephalopathy Rats

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Blockade of NR2A-Containing NMDA Receptors Induces Tau Phosphorylation in Rat Hippocampal Slices

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Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress

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Up-regulation of GluN2A-containing NMDA receptor protects cultured cortical neuron cells from oxidative stress

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MTEP, a Selective mGluR5 Antagonist, Had a Neuroprotective Effect but Did Not Prevent the Development of Spontaneous Recurrent Seizures and Behavioral Comorbidities in the Rat Lithium–Pilocarpine Model of Epilepsy

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Sensing of amino acids: Critical role of nanomaterials for the efficient biomedical analysis

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Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position

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Lack of efficacy of NMDA receptor-NR2B selective antagonists in the R6/2 model of Huntington disease

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Hypoxia-Induced Activation ofN-methyl-D-aspartate Receptors Causes Retinal Ganglion Cell Death in the Neonatal Retina

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Apolipoprotein D Overexpression Protects Against Kainate-Induced Neurotoxicity in Mice

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Neuroprotective Effects of Flax Lignan Against NMDA ‐Induced Neurotoxicity In Vitro

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Reduced spatial learning in mice treated with NVP-AAM077 through down-regulating neurogenesis

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TFP5 peptide, derived from CDK5-activating cofactor p35, provides neuroprotection in early-stage of adult ischemic stroke

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Chronic Monoarthritis Pain Accelerates the Processes of Cognitive Impairment and Increases the NMDAR Subunits NR2B in CA3 of Hippocampus from 5-month-old Transgenic APP/PS1 Mice

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Electroacupuncture Pretreatment Elicits Tolerance to Cerebral Ischemia/Reperfusion through Inhibition of the GluN2B/m-Calpain/p38 MAPK Proapoptotic Pathway

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Achyranthes bidentata polypeptides prevent apoptosis by inhibiting the glutamate current in cultured hippocampal neurons

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CGX-1007 prevents excitotoxic cell death via actions at multiple types of NMDA receptors

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Carthamus tinctorius L. ameliorates brain injury followed by cerebral ischemia-reperfusion in rats by antioxidative and anti-inflammatory mechanisms.

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Oxidative stress accelerates synaptic glutamate dyshomeostasis and NMDARs disorder during methylmercury‐induced neuronal apoptosis in rat cerebral cortex

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Various facets of excitotoxicity

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Reperfusion and cytoprotective agents are a mutually beneficial pair in ischaemic stroke therapy: an overview of pathophysiology, pharmacological targets and candidate drugs focusing on excitotoxicity and free radical

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Manganese exposure alters the expression of N ‐methyl‐ d ‐aspartate receptor subunit mRNAs and proteins in rat striatum

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The Therapeutic Role of d-Cycloserine in Schizophrenia

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Estrogen Alters the Synaptic Distribution of Phospho-GluN2B in the Dorsolateral Prefrontal Cortex While Promoting Working Memory in Aged Rhesus Monkeys

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Active fraction combination from Liuwei Dihuang decoction (LW-AFC) ameliorates corticosterone-induced long-term potentiation (LTP) impairment in mice in vivo

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Depression, Estrogens, and Neuroinflammation: A Preclinical Review of Ketamine Treatment for Mood Disorders in Women

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Suprachiasmatic nucleus neurons display endogenous resistance to excitotoxicity

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Bidentatide, a Novel Plant Peptide Derived from Achyranthes bidentata Blume: Isolation, Characterization, and Neuroprotection through Inhibition of NR2B-Containing NMDA Receptors

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Lycium barbarum Ameliorates Neural Damage Induced by Experimental Ischemic Stroke and Radiation Exposure

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GABA synaptopathy promotes the elevation of caspases 3 and 9 as pro-apoptotic markers in Egyptian patients with autism spectrum disorder

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N-Methyl- -Aspartate receptor and inflammation in dorsolateral prefrontal cortex in schizophrenia

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Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain

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Synthesis and biological evaluation of radio-iodinated benzimidazoles as SPECT imaging agents for NR2B subtype of NMDA receptor

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Astrocytes increase the activity of synaptic GluN2B NMDA receptors

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Glycine bidirectionally regulates ischemic tolerance via different mechanisms including NR2A‐dependent CREB phosphorylation

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Postsynaptic density-93 deficiency protects cultured cortical neurons from N-methyl- -aspartate receptor-triggered neurotoxicity

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Slice orientation and muscarinic acetylcholine receptor activation determine the involvement of N-methyl D-aspartate receptor subunit GluN2B in hippocampal area CA1 long-term depression

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Anxious phenotypes plus environmental stressors are related to brain DNA damage and changes in NMDA receptor subunits and glutamate uptake

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Psoralidin Stimulates Expression of Immediate-Early Genes and Synapse Development in Primary Cortical Neurons

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Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension

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N-Methyl-D-Aspartate Receptor Signaling-Protein Kinases Crosstalk in Cerebral Ischemia

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Maternal high‐sugar diet results in NMDA receptors abnormalities and cognitive impairment in rat offspring

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Differential regulation of NMDA receptor function by DJ‐1 and PINK1

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Genistein inhibits amyloid peptide 25-35-induced neuronal death by modulating estrogen receptors, choline acetyltransferase and glutamate receptors

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BmK NT1-induced neurotoxicity is mediated by PKC/CaMKⅡ-dependent ERK1/2 and p38 activation in primary cultured cerebellar granule cells

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Amelioration of lipopolysaccharide-induced memory impairment in equilibrative nucleoside transporter-2 knockout mice is accompanied by the changes in glutamatergic pathways

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C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction

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Deciphering the Enigma of Neuron-Glial Interactions in Neurological Disorders

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Alterations in mRNA and Protein Expression of Glutamate Receptor Subunits Following Pentylenetetrazole-induced Acute Seizures in Young Rats

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Two-Chains Tissue Plasminogen Activator Unifies Met and NMDA Receptor Signalling to Control Neuronal Survival

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Bi‐directional regulation of CaMKIIα phosphorylation at Thr286 by NMDA receptors in cultured cortical neurons

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Differential roles of GluN2A- and GluN2B-containing NMDA receptors in neuronal survival and death.

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Dichotomy in the anxiolytic versus antidepressant effect of C-terminal truncation of the GluN2A subunit of NMDA receptors

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NMDA receptor activity determines neuronal fate: location or number?

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NMDA receptors promote neurogenesis in the neonatal rat subventricular zone following hypoxic-ischemic injury

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Comparison of the pharmacological properties of GK11 and MK801, two NMDA receptor antagonists: towards an explanation for the lack of intrinsic neurotoxicity of GK11

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Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists

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Association of concussion history with psychiatric symptoms, limbic system structure, and kynurenine pathway metabolites in healthy, collegiate-aged athletes

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Systemic Administration of an Apelin Receptor Agonist Prevents NMDA-Induced Loss of Retinal Neuronal Cells in Mice

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Rabphilin-3A undergoes phase separation to regulate GluN2A mobility and surface clustering

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Subunit-specific effects of NMDA receptor signaling: Implications for stroke

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Opposing roles of NMDA receptor subtypes in neuronal fate and novel treatments for ischemic brain injury

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Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors

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Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: Evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects

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