NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both In Vitro and In Vivo

Reversible middle cerebral artery occlusion without craniectomy in rats.

Longa, E. Z., Weinstein, P. R., Carlson, S., & Cummins, R. (1989) · Stroke · doi:10.1161/01.str.20.1.84 · Cited by 7,463

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

Monyer, H., Burnashev, N., Laurie, D. J., Sakmann, B., & Seeburg, P. H. (1994) · Neuron · doi:10.1016/0896-6273(94)90210-0 · Cited by 3,535

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

Benveniste, H., Drejer, J., Schousboe, A., & Diemer, N. H. (1984) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1984.tb05396.x · Cited by 2,863

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

Bederson, J. B., Pitts, L. H., Tsuji, M., Nishimura, M. C., Davis, R. L., & Bartkowski, H. (1986) · Stroke · doi:10.1161/01.str.17.3.472 · Cited by 2,681

Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders

Epstein, F. H., Lipton, S. A., & Rosenberg, P. A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199403033300907 · Cited by 2,676

Regulation of neuronal survival by the serine-threonine protein kinase Akt

Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R., Cooper, G. M., Segal, R. A., Kaplan, D. R., & Greenberg, M. E. (1997) · Science · doi:10.1126/science.275.5300.661 · Cited by 2,436

Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain

Ikonomidou, C., Bosch, F., Miksa, M., Bittigau, P., Vöckler, J., Dikranian, K., Tenkova, T. I., Stefovska, V., Turski, L., & Olney, J. W. (1999) · Science · doi:10.1126/science.283.5398.70 · Cited by 2,055

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.

Bonfoco, E., Krainc, D., Ankarcrona, M., Nicotera, P., & Lipton, S. A. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.16.7162 · Cited by 1,958

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

Hardingham, G. E., Fukunaga, Y., & Bading, H. (2002) · Nature Neuroscience · doi:10.1038/nn835 · Cited by 1,686

Functional Repression of cAMP Response Element in 6-Hydroxydopamine-treated Neuronal Cells

Chalovich, E. M., Zhu, J.-H., Caltagarone, J., Bowser, R., & Chu, C. T. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602632200 · Cited by 1,385

Discovery of novel positive allosteric modulators targeting GluN1/2A NMDARs as anti-stroke therapeutic agents

Zhu, H., Chen, X., Zhang, L., liu, X., Ji, C., Zhang, H., & Dong, M. (2024) · RSC Medicinal Chemistry · doi:10.1039/d3md00455d · Cited by 6

Neuroprotective effects of MK-801 against cerebral ischemia reperfusion

Yaghoobi, Z., Ataei, S., Riahi, E., Parviz, M., Sehati, F., Zare, M., Angizeh, R., Ashabi, G., & Hosseindoost, S. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e33821 · Cited by 6

Fluorescence and Bioluminescence Imaging of Subcellular Ca2+ in Aged Hippocampal Neurons

Calvo-Rodríguez, M., Villalobos, C., & Núñez, L. (2015) · Journal of Visualized Experiments · doi:10.3791/53330 · Cited by 6

Spinophilin‐dependent regulation of GluN2B‐containing NMDAR‐dependent calcium influx, GluN2B surface expression, and cleaved caspase expression

Salek, A. B., Claeboe, E. T., Bansal, R., Berbari, N. F., & Baucum, A. J. (2023) · Synapse · doi:10.1002/syn.22264 · Cited by 6

Tonic Activation of NR2D-Containing NMDARs Exacerbates Dopaminergic Neuronal Loss in MPTP-Injected Parkinsonian Mice

Sharma, R., Neupane, C., Phạm, T. L., lee, M., Lee, S., Lee, S. Y., Nam, M., Kim, C., & Park, J. B. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.1955-22.2023 · Cited by 6

Novel rare variations in genes that regulate developmental change in N-methyl-d-aspartate receptor in patients with schizophrenia

Yoshikawa, A., Nishimura, F., Inai, A., Eriguchi, Y., Nishioka, M., Takaya, A., Tochigi, M., Kawamura, Y., Umekage, T., Kato, K., et al. (2018) · Human Genome Variation · doi:10.1038/hgv.2017.56 · Cited by 6

Id1/NR2B Receptor Pathway Regulates Rat Cochlear Sensory Epithelial Cell Survival after Radiation

Chen, J., Zhou, X., Zou, T., Wang, B.-C., Yu, Y., Lin, F., Chen, K., Lai, Y., & Sun, K. (2018) · Audiology and Neurotology · doi:10.1159/000493084 · Cited by 6

Bilateral transcranial direct-current stimulation confers neuroprotection through suppression of PKM2 after mouse cerebral ischemia injury

Ren, J., Gao, J., Yao, X., Wang, X., Kong, X., Lin, T., Wang, H., Ma, W., Glebov, O. O., & Wan, Q. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149353 · Cited by 5

Chemical characterization, neuroprotective effect, and in-silico evaluation of the petroleum ether extract of three palm tree species against glutamate-induced excitotoxicity in rats

Moharram, F. A.-E., Hamed, F. M., El-Sayed, E. K., Mohamed, S. K., Ahmed, A. A., El-Gayed, S. H., Abdelrazek, M., Lai, K.-H., Mansour, Y. E., Mady, M. S., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e39207 · Cited by 5

Amelioration by glycine of brain damage in neonatal rat brain following hypoxia–ischemia

Mori, H., Momosaki, K., Kido, J., Naramura, T., Tanaka, K., Matsumoto, S., Nakamura, K., Mitsubuchi, H., Endo, F., & Iwai, M. (2016) · Pediatrics International · doi:10.1111/ped.13164 · Cited by 5

A beneficial role for elevated extracellular glutamate in Amyotrophic Lateral Sclerosis and cerebral ischemia

Schiel, K. A. (2021) · BioEssays · doi:10.1002/bies.202100127 · Cited by 5

Development and Validation of [3H]OF-NB1 for Preclinical Assessment of GluN1/2B Candidate Drugs

Ahmed, H., Gisler, L., Elghazawy, N. H., Keller, C., Sippl, W., Liang, S. H., Haider, A., & Ametamey, S. M. (2022) · Pharmaceuticals · doi:10.3390/ph15080960 · Cited by 5

N‐methyl‐D ‐aspartic acid receptor 2A functionalized stationary phase: A reliable method for pursuing potential ligands against Alzheimer's disease from natural products

Chen, Y., Xue, Y., Yin, J., Qu, L., Li, H., Li, Q., & Zhao, X. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14101 · Cited by 6

Neuroprotectants Targeting NMDA Receptor Signaling

Vetiska, S., & Tymianski, M. (2014) · Springer eBooks · doi:10.1007/978-1-4614-5836-4_168 · Cited by 5

Adult neural stem/progenitor cells reduce NMDA‐induced excitotoxicity via the novel neuroprotective peptide pentinin

Faijerson, J., Thorsell, A., Strandberg, J., Hanse, E., Sandberg, M., Eriksson, P. S., & Tinsley, R. B. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06016.x · Cited by 4

2B or Not 2B: A Tail of Two NMDA Receptor Subunits

Cepeda, C., & Levine, M. S. (2012) · Neuron · doi:10.1016/j.neuron.2012.04.011 · Cited by 5

Effect of phosphomimetic mutations on the C-terminal sensitivity of glycine transporter GlyT1 to calpain

Miháliková, A., Baliova, M., & Jurský, F. (2014) · Neuroscience Research · doi:10.1016/j.neures.2014.02.007 · Cited by 5

Microdissection and transcriptional profiling

Majer, A., & Booth, S. A. (2014) · Prion · doi:10.4161/pri.27729 · Cited by 6

An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons

Hayashi, Y., Morinaga, S., Liu, X., Zhang, J., Wu, Z., Yokoyama, T., & Nakanishi, H. (2016) · Mediators of Inflammation · doi:10.1155/2016/5079597 · Cited by 5

Cholesterol and Fat Metabolism in Alzheimer’s Disease

Taghibiglou, C., & Khalaj, S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802810-0.00009-x · Cited by 5

Effects of ischemic preconditioning on PDGF-BB expression in the gerbil hippocampal CA1 region following transient cerebral ischemia

Lee, J., Kim, Y. H., Lee, T.-K., Kim, I. H., Cho, J.-H., Cho, G., Shin, B. N., Park, J. H., Ahn, J. H., Shin, M. C., et al. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.6799 · Cited by 5

Chronic Binge Alcohol-Associated Differential Brain Region Modulation of Growth Factor Signaling Pathways and Neuroinflammation in Simian Immunodeficiency Virus-Infected Male Macaques

Maxi, J. K., Mercante, D., Foret, B. L., Oberhelman, S., Ferguson, T. F., Bagby, G. J., Nelson, S., Amedee, A. M., Edwards, S., Simon, L., et al. (2019) · Alcohol and Alcoholism · doi:10.1093/alcalc/agz056 · Cited by 5

Glutamate Attenuates the Survival Property of IGFR through NR2B Containing N-Methyl-D-aspartate Receptors in Cortical Neurons

Zhao, X., Han, C., Zeng, Z., Liu, L., Wang, H., Xu, J., Feng, Z., Little, P. J., Quirion, R., & Zheng, W. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/5173184 · Cited by 5

Protective effect of Achyranthes bidentata polypeptides on NMDA-mediated injury is developmentally regulated via modulating NR2A and NR2B differentially

Hu, W., He, J., Wang, Y., Xu, L., Zhao, Y., Hu, X., & Shen, H. (2021) · Annals of Translational Medicine · doi:10.21037/atm-20-581 · Cited by 5

Change in gene expression levels of GABA, glutamate and neurosteroid pathways due to acoustic trauma in the cochlea

Güneş, M. C., Güneş, M. S., Vural, A., Aybuga, F., Bayramov, R., Bayram, K. K., Şahin, M. İ., Doğan, M. E., Ozdemir, S. Y., & Özkul, Y. (2021) · Journal of Neurogenetics · doi:10.1080/01677063.2021.1904922 · Cited by 5

HIV-Induced Hyperactivity of Striatal Neurons Is Associated with Dysfunction of Voltage-Gated Calcium and Potassium Channels at Middle Age

Khodr, C. E., Chen, L., Al‐Harthi, L., & Hu, X. (2022) · Membranes · doi:10.3390/membranes12080737 · Cited by 5

Possible Effects of Acupuncture in Poststroke Aphasia

Zhuo, B., Deng, S., Li, B., Zhu, W., Zhang, M., Qin, C., & Meng, Z. (2023) · Behavioural Neurology · doi:10.1155/2023/9445381 · Cited by 5

NMDA-gated ion channel research and its therapeutic potentials in neurodegenerative diseases: a review

Chen, H.-S. V., & Majdi, M. (2009) · Journal of Receptor Ligand and Channel Research · doi:10.2147/jrlcr.s4498 · Cited by 5

NMDAR inhibitor preconditioned mesenchymal stromal cell-derived extracellular vesicles enhance post-stroke recovery by targeting excitotoxicity and neuronal regeneration

Zhang, X., Tian, H., Bo, H., & Zhong, L. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1608615 · Cited by 4

Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer’s disease

Imiruaye, O. E., Perez, I. G., Carson, B. C., Crouzet, C., Garcia, J., Han, D., & Bhattacharya, S. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1649625 · Cited by 4

Neurotoxicity of General Anesthetics in the Developing Brain: Insight into the Glutamate and GABA Receptor Signalling

Lei, L., Ji, M., Meng, Q., & Yang, J. (2022) · Journal of Anesthesia and Translational Medicine · doi:10.58888/2957-3912-20220103 · Cited by 4

2-BFI protects against ischemic stroke by selectively acting on NR2B-containing NMDA receptors

Xu, S., Chen, J., Xu, C., Xu, Y., Xu, L., Zhao, M., Xu, T. W., Cao, Y., Li, P., & Han, Z. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149284 · Cited by 4

Synaptic and Extra-Synaptic NMDA Receptors in the CNS

Papouin, T., & Oliet, S. H. R. (2017) · Springer eBooks · doi:10.1007/978-3-319-49795-2_2 · Cited by 4

Researches of the imidazole and indole derivatives cerebroprotective activity and its impact on effects of antidepressants

Абрамец, И. И., Зайка, Т. О., Евдокимов, Д. В., Kuznetsov, Y. V., & Sidorova, Y. V. (2020) · Pharmacokinetics and Pharmacodynamics · doi:10.37489/2587-7836-2020-1-18-24 · Cited by 4

Developmental plasticity of NMDA receptors at the calyx of Held synapse

Gurma, M., Yang, Y., & Wang, L. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108697 · Cited by 4

Intragastric administration of prednisone acetate induced impairment of hippocampal long-term potentiation

Wang, Y., Xiang, S., Zhang, M., Zhang, J., & Ding, X. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148270 · Cited by 4

Pharmacological Potential of 3-Benzazepines in NMDAR-Linked Pathophysiological Processes

Ritter, N., Disse, P., Wünsch, B., Seebohm, G., & Strutz‐Seebohm, N. (2023) · Biomedicines · doi:10.3390/biomedicines11051367 · Cited by 4

Mitochondrial Regulators of Synaptic Plasticity in the Ischemic Brain

Park, H., & Jonas, E. A. (2017) · InTech eBooks · doi:10.5772/67126 · Cited by 4

The positive allosteric modulation of GABAA receptors mRNA in immature hippocampal rat neurons by midazolam affects receptor expression and induces apoptosis

Sinner, B., Steiner, J., Malsy, M., Graf, B. M., & Bundscherer, A. (2019) · International Journal of Neuroscience · doi:10.1080/00207454.2019.1604524 · Cited by 4

Stimulation of GluN receptors decreases the surface density of GluN1/GluN2B subunits in cultured neocortical interneurons

Nörenberg, W., Lindemeyer, A. K., Wilmes, T., Sobottka, H., & Meyer, D. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2012.07718.x · Cited by 4

The role of AMPA receptor-mediated excitotoxicity in ALS: Is deficient RNA editing to blame?

Duncan, K. (2009) · Current Anaesthesia and Critical Care · doi:10.1016/j.cacc.2009.07.010 · Cited by 4

Presenilin-1/γ-Secretase Controls Glutamate Release, Tyrosine Phosphorylation, and Surface Expression of N-Methyl-d-aspartate Receptor (NMDAR) Subunit GluN2B

Zhao, X., Barthet, G., Shioi, J., Xu, J., Georgakopoulos, A., Bruban, J., & Robakis, N. K. R. K. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.499004 · Cited by 4

Decreased levels of pNR1 S897 protein in the cortex of neonatal Sprague Dawley rats with hypoxic-ischemic or NMDA-induced brain damage

Hei, M., Tao, H.-K., Tang, Q., Yu, B., & Zhao, L. (2012) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2012007500100 · Cited by 4

Multitarget Drugs for Stabilization of Calcium Cycling and Neuroprotection in Neurodegenerative Diseases and Stroke

de Diego, A. M. G., Lorrio, S., Hernández-Guijo, J. M., Gandía, L., & de Diego, A. M. G. (2012) · Wiley eBooks · doi:10.1002/9781118185537.ch4 · Cited by 4

Hierarchical Bayesian model of population structure reveals convergent adaptation to high altitude in human populationsPreprint

Foll, M., Gaggiotti, O. E., Daub, J. T., & Excoffier, L. (2014) · arXiv (Cornell University) · Cited by 4

Effects of clitorienolactones from Clitoria ternatea root on calcium channel mediating hippocampal long-term potentiation in rats induced chronic cerebral hypoperfusion

Ahad, M. A., Chear, N. J., Abdullah, M. H., Ching-Ga, T. A. F., Liao, P. H., Wei, S., Murugaiyah, V., & Hassan, Z. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102252 · Cited by 3

Analysis of genetic data in for implementation of compression algorithm in Alzheimer's Disease database

Yassin, A. I. M., Abidin, H. Z., Baharom, R., Saat, E. H. M., & Zabidi, A. (2010) · IEEE-EMBS Conference on Biomedical Engineering and Sciences · doi:10.1109/iecbes.2010.5742291 · Cited by 3

Sex-Dependent Differences in the Ischemia/Reperfusion-Induced Expression of AMPA Receptors

Achzet, L. M., & Jackson, D. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042231 · Cited by 3

The NMDA Receptors: Physiology and Neurotoxicity in the Developing Brain

Gu, Q., & Wang, C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809405-1.00018-3 · Cited by 3

Identification of N-methyl-D-aspartate receptor antagonists using the rat postnatal mixed cortical and hippocampal neurons

Voldřich, J., Matoušová, M., Šmídková, M., Slavı́ková, B., Chodounská, H., Kudová, E., & Mertlíková‐Kaiserová, H. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175056 · Cited by 3

Mechanisms of Calcium Influx Following Stroke

Belrose, J. C., Caetano, F. A., Yang, K., Lockhart, B. M. W., Jackson, M. F., & MacDonald, J. F. (2012) · Springer eBooks · doi:10.1007/978-1-4419-9663-3_2 · Cited by 3

Impact of Early Life Ketamine Exposure on the Developing Brain and Cognitive Sequelae

Kokane, S. S., & Lin, Q. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800212-4.00054-6 · Cited by 3

Regulation of Vulnerability to NMDA Excitotoxicity During Postnatal Maturation

Marks, J. D. (2009) · Contemporary clinical neuroscience · doi:10.1007/978-1-60327-579-8_1 · Cited by 3

The Effect of Glycine max Extract Diets on Changes in NR2B Gene Expression, Cognitive Vitality and Neurotoxicity in High Concentrate Consumption

Shahib, M. N., Syamsunarno, M. R. A. A., Faried, A., Yuliana, D., Anggraeni, D. I., Yuniarti, L., & Tih, F. (2009) · The Kitakanto Medical Journal · doi:10.2974/kmj.60.41 · Cited by 3

Acute Hypoxia Differentially Affects the NMDA Receptor NR1, NR2A and NR2B Subunit mRNA Levels in the Developing Chick Optic Tectum: Stage-Dependent Plasticity in the 2B–2A Ratio

Vacotto, M., Rapacioli, M., Flores, V., & de Plazas, S. F. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0221-4 · Cited by 3

Neuroprotective Effect of Moxibustion on Cerebral Ischemia/Reperfusion Injury in Rats by Downregulating NR2B Expression

Di, Z., Guo, Q., & Zhang, Q. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/5370214 · Cited by 3

NMDA and Dopamine

Jocoy, E. L., Cepeda, C., Levine, M. S., & André, V. M. (2008) · Frontiers in neuroscience · doi:10.1201/9781420044157.ch3 · Cited by 3

Nanoelectronics for Neuroscience

Rastogi, S. K., & Cohen‐Karni, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99893-3 · Cited by 3

Characterization of (R)- and (S)-[18F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl- d -Aspartate Receptors

Ahmed, H., Wallimann, R. H., Gisler, L., Elghazawy, N. H., Gruber, S., Keller, C., Liang, S. H., Sippl, W., Haider, A., & Ametamey, S. M. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00519 · Cited by 2

GluN2A–NMDAR mediated neuronal NFκB activation plays a key role in exacerbating ischemic brain injury under hyperhomocysteinemic conditions

Seelig, S., Paramasivam, P., Gomez, M., Smith, A., Miller, J. W., Paul, S., & Poddar, R. (2025) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x251399012 · Cited by 2

Mechanisms and Implications of Mitochondrial Autophagy in Stroke

Sultan, R., Zou, Q., Cao, Y., Hong, H., Sun, R., Zhuang, C., Zhao, R. C., & Wang, J. (2024) · Neuropharmacology and Therapy · doi:10.15212/npt-2024-0005 · Cited by 2

NP10679: A new horizon for neuroprotection in aneurysmal subarachnoid hemorrhage

García‐Bonilla, L. (2025) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/j.jpet.2025.103390 · Cited by 2

Factors Contributing to Resistance to Ischemia-Reperfusion Injury in Olfactory Mitral Cells

Lee, C. H., Ahn, J. H., & Won, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26115079 · Cited by 2

N-Methyl-D-Aspartate Receptors Mediate Excitotoxicity in Amyloid Beta-Induced Synaptic Pathology of Alzheimer’s Disease

Liu, J., Gao, X., & Wu, Y. (2008) · Neuroembryology and Aging · doi:10.1159/000193851 · Cited by 2

NMDA receptor expression and C terminus structure in the rotifer Brachionus plicatilis and long-term potentiation across the Metazoa

Kenny, N. J., & Dearden, P. K. (2013) · Invertebrate Neuroscience · doi:10.1007/s10158-013-0154-0 · Cited by 2

Effects of L-Dopa and Dopamine D2 Agonists on Recollection and Familiarity in Idiopathic Nondementing Parkinson’s Disease

Edelstyn, N. M. J., Shepherd, T. A., Mayes, A. R., Sherman, S. M., & Ellis, S. J. (2011) · Neuroscience & Medicine · doi:10.4236/nm.2011.24042 · Cited by 2

The influence of NMDA receptor 2B subunit (GRIN2B) on cortical electrical oscillation

Lee, T., Yu, Y. W. ‐., Hong, C., Tsai, S., Wu, H.-C., & Chen, T. (2011) · World Journal of Neuroscience · doi:10.4236/wjns.2011.13006 · Cited by 2

Effects of NMDA Receptors in Synapses and Extrasynapses of Rat Hippocampal Neurons on Amyloid-Beta-Induced Alterations in PSD-95 Expression

Liu, J., Wu, Y., Chang, L., Peng, J., Song, Y., Lu, T., & Gao, X. (2008) · Neuroembryology and Aging · doi:10.1159/000183034 · Cited by 2

Molecular imaging as the main part of our decision-making and treatment strategies in stroke

Kashefi, A. (2007) · Frontiers in bioscience · doi:10.2741/2779 · Cited by 2

Posttraumatic Seizures and Epileptogenesis

Giza, C. C. (2010) · Epilepsy · doi:10.1201/9781420085594-c12 · Cited by 3

Huntington's Disease and Other Choreas

Salman, H., Wild, E. J., & Tabrizi, S. J. (2017) · Neurodegeneration · doi:10.1002/9781118661895.ch21 · Cited by 2

Therapeutic effect of erythropoietin and its derivatives in the treatment of acute ischemic stroke

Rama, R., & Torrella, J. R. (2025) · Exploration of Neuroprotective Therapy · doi:10.37349/ent.2025.1004101 · Cited by 1

Acute liver failure in rats triggers region-specific modulation of NMDAR subunits and induces nNOS-NO-cGMP cascades in the cerebral cortex and cerebellum

Singh, S., Mukherjee, A., Dusmanta, P., & Jeswani, D. (2025) · Brain Mechanisms · doi:10.1016/j.bramec.2025.202519 · Cited by 1

Regulation of Ischemic Long-Term Potentiation in GluN2B and FKBP51 Underlying Cathodal Direct Current Stimulation

Lee, C. J., Tang, C., Chang, C.-H., Chia, C.-M., Hsieh, T.-H., Chi, H., & Lin, H. (2025) · Neurochemical Research · doi:10.1007/s11064-025-04578-6 · Cited by 1

GluN2B-specific NMDAR positive allosteric modulation reverses cognitive and behavioral abnormalities in Mecp2 and Disc1 transgenic mice

Ge, Y., Tian, T., Li, B., Axerio-Cilies, P., Chen, W., Qin, X. Y., Zhao, M., Sun, Q., Li, J., Floresco, S., et al. (2026) · Science Advances · doi:10.1126/sciadv.ady3891 · Cited by 1

Brain Ischemia and Neuronal Excitability

Deng, P., & Xu, Z. C. (2009) · Contemporary clinical neuroscience · doi:10.1007/978-1-60327-579-8_3 · Cited by 1

Amide of Lambertian Acid Suppresses Hyperactivation of Inotropic Glutamate Receptors, but not Synaptic Potentiation in Hippocampal Sections

Vechkapova, S. O., Запара, Т. А., Morozova, E. A., Proskura, A. L., Schul’ts, E. E., Tolstikova, T. G., & Ratushnyak, A. S. (2016) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-016-3509-9 · Cited by 1

The Dichotomous Role of N-methyl-D-Aspartate Receptors in Ischemic Stroke

Balsara, R. D. (2018) · Journal of Cardiology and Cardiovascular Sciences · doi:10.29245/2578-3025/2018/4.1133 · Cited by 1

Effect of Pinealon on Learning and Expression of NMDA Receptor Subunit Genes in the Hippocampus of Rats with Experimental Diabetes

Karantysh, G. V., Фоменко, М. П., Menzheritsky, A. M., Прокофьев, В. Н., Ryzhak, G. A., & Butenko, E. V. (2020) · Neurochemical Journal · doi:10.1134/s181971242003006x · Cited by 1

Changes in NMDA Receptor Function in Rapid Ischemic Tolerance: A Potential Role for Tri-Heteromeric NMDA Receptors

Xie, M., Leng, T., Maysami, S., Pearson, A. N., Simon, R. P., Xiong, Z., & Meller, R. (2022) · Biomolecules · doi:10.3390/biom12091214 · Cited by 1

3′-Daidzein Sulfonate Sodium Protects against Glutamate-induced Neuronal Injuries by Regulating NMDA Receptors

Feng, R., Luo, L., Han, Z., Qi, Y., Xiao, H. T., Huang, C., Peng, W., Liu, R., & Huang, Z. (2024) · Current Pharmaceutical Design · doi:10.2174/0113816128299123240505172222 · Cited by 1

Mechanism of Ammonia‐Induced Brain Damage in Chinese Striped‐Necked Turtle ( Mauremys sinensis )

Xiao, Y., Niu, X., Jiao, X., Lin, L., Shi, H., Hong, M., & Ding, L. (2025) · Integrative Zoology · doi:10.1111/1749-4877.12997 · Cited by 1

Synaptic and extrasynaptic NMDA receptors: Problems and prospects

Kudryashova, I. V. (2007) · Neurochemical Journal · doi:10.1134/s1819712407040022 · Cited by 1

NMDA-induced Excitotoxicity and Lactate Dehydrogenase Assay in Primary Cultured Neurons

Zhang, S., & Wang, Y. T. (2013) · BIO-PROTOCOL · doi:10.21769/bioprotoc.965 · Cited by 1

Antidepressant-like effects of substances with cerebroprotective activity

Зайка, Т. О., Евдокимов, Д. В., Sidorova, Y. V., Абрамец, И. И., & Nalotov, S. V. (2015) · Biological Markers and Guided Therapy · doi:10.12988/bmgt.2015.5117 · Cited by 1

The Increased Channel Activity of N-Methyl-D-Aspartate Receptors at Extrasynaptic Sites in the Anterior Cingulate Cortex of Neonatal Rats Following Prolonged Ketamine Exposure

Jin, J.-H., Wang, R., & Lin, Q. (2021) · Journal of Pain Research · doi:10.2147/jpr.s320674 · Cited by 1

Comparative Investigation of Expression of Glutamatergic and GABAergic Genes in the Rat Hippocampus after Focal Brain Ischemia and Central LPS Administration

Kalinina, T. S., Shishkina, G. T., Lanshakov, D. A., Sukhareva, E. V., Onufriev, M. V., Moiseeva, Y. V., Gulyaeva, N. V., & Дыгало, Н. Н. (2023) · Biochemistry (Moscow) · doi:10.1134/s0006297923040090 · Cited by 1

TRPM2 in the Central Nervous System: Physiological Role and Critical Regulatory Pathways

Belrose, J. C. (2012) · Scholarship@Western (Western University) · Cited by 1

Clinically Tolerated Strategies for NMDA Receptor Antagonism

Chen, H.-S. V., Zhang, D., & Lipton, S. A. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-055-3_8 · Cited by 1

Mitochondrial Ca2+ Dysregulation During Stroke and Cell Death

Sisalli, M. J., Savoia, C., & Scorziello, A. (2012) · Springer eBooks · doi:10.1007/978-1-4419-9663-3_3 · Cited by 1

Dopamine Receptor Modulation of Glutamatergic Neurotransmission

Cepeda, C., André, V. M., Jocoy, E. L., & Levine, M. S. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-333-6_11 · Cited by 1

Testing of neuroprotective compounds in a transgenic mouse model of Huntington's disease

Zádori, D. (2011) · doi:10.14232/phd.644 · Cited by 1

Efectos de los pesticidas organoclorados sobre la neurotransmisión glutamatérgica en cultivos primarios neuronales. Interacciones con el sistema neuroendocrino.

Herrezuelo, V. B. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 1

The role of CaMKII binding NMDARs in synaptic plasticity and memory

Dallapiazza, R. F. (2010) · doi:10.17077/etd.ut2qb8ib

Mechanisms of Neuronal Death Induced by Environmental Toxicants in Murine Cortical Culture

Rush, T. (2011)

An in vitro and in silico investigation of the role of NMDA receptor subtypes following mechanical injury

Singh, P. K. (2011) · ScholarlyCommons (University of Pennsylvania)

Anatomy and Function of Synaptic Zinc in the Striatum

Thackray, S. E. (2015) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/24841

Envolvimento de Rac1 na excitotoxicidade induzida por NMDA na retina de ratos.

Saito, K. C. (2011) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2011.tde-10022012-132908

The Role of Striatal-Enriched Tyrosine Phosphatase in Regulating Excitotoxic Cell Death

Austin, D. R. (2008) · doi:10.14418/wes01.1.297

The prefrontal cortex and information processing : nitric oxide signaling studied in an animal model of schizophrenia

Fejgin, K. (2008) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Subunit-specific effects of NMDA receptor signaling: Implications for stroke

Liu, Y., Wong, T. P., Aarts, M. M., Liu, L., Wu, D., Lu, J., Tymianski, M., & Wang, Y.-T. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9591524.0431

Opposing roles of NMDA receptor subtypes in neuronal fate and novel treatments for ischemic brain injury

Liu, Y. (2010) · cIRcle (University of British Columbia) · doi:10.14288/1.0092964

Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors

von Engelhardt, J., Coserea, I., Pawlak, V., Fuchs, E. C., Köhr, G., Seeburg, P. H., & Monyer, H. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.04.015 · Cited by 151

Molecular mechanisms of NMDA receptor-mediated excitotoxicity: Implications for neuroprotective therapeutics for stroke

Wang, Y., & Li, V. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.194713 · Cited by 55

Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: Evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects

Vizi, E. S., Kisfali, M., & Lőrincz, T. (2012) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2012.10.005 · Cited by 125