Cited by 238Deep Brain Stimulation and Movement DisordersNeurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.

The Nigrostriatal Pathway in the Rat: A Single-Axon Study of the Relationship between Dorsal and Ventral Tier Nigral Neurons and the Striosome/Matrix Striatal Compartments

Open access

Prensa, Lucı́a, Parent, André·2001·The Journal of Neuroscience

DOI 10.1523/jneurosci.21-18-07247.2001PMC PMC6762986

Open this paper in CoChat — free account Open PDF

Abstract

Axons from dorsal/ventral tiers of substantia nigra pars compacta (SNc), ventral tegmental area (VTA), and retrorubral field (RRF) were traced after injecting their cell body with biotinylated dextran amine. Fifty-three single axons were reconstructed from serial sagittal sections with a camera lucida, and mu-opiate receptor immunostaining served to differentiate the striosome/matrix striatal compartments. Most dorsal tier SNc axons terminate within the matrix of the dorsal striatum, but their patterns of arborization vary markedly; some axons innervate one specific matriceal area, whereas others arborize in multiple discontinuous loci. Some dorsal tier SNc axons also project to both striosomes and matrix. Other dorsal tier SNc axons, as well as VTA axons, innervate the ventral striatum and send collaterals to striosomes lying ventrally in the dorsal striatum or to the ventral sector of the subcallosal streak (SS). Ventral tier SNc axons arborize principally in striosomes, but some ramify in both compartments or in striosomes and the SS. Ventral tier neurons that form deep clusters in substantia nigra pars reticulata innervate principally the matrix and the SS. The amygdala and ventral pallidum receive secondary collaterals from striatal axons of dorsal/ventral tier neurons or RRF neurons. The subthalamic nucleus receives collaterals from striatal axons of SNc clustered neurons, whereas the globus pallidus gets collaterals from striatal axons of dorsal/ventral tier SNc neurons. These findings reveal that the nigrostriatal pathway is composed of several neuronal subsystems, each endowed with a widely distributed axonal arborization that allows them to exert a multifaceted influence on striatal and/or extrastriatal structures.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1523/jneurosci.21-18-07247.2001

Cites

62 of 62 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The rat brain in stereotaxic coordinates
Palkovits, M. (1983) · Neuropeptides · doi:10.1016/0143-4179(83)90049-5 · Cited by 28,959
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.
Hsu, S. M., Raine, L., & Fanger, H. (1981) · Journal of Histochemistry & Cytochemistry · doi:10.1177/29.4.6166661 · Cited by 14,075
EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.
Dahlstroem, A., & Fuxé, K. (1964) · PubMed · Cited by 5,133
AChE-stained horizontal sections of the rat brain in stereotaxic coordinates
Paxinos, G., WATSON, C. R. R., & Emson, P. C. (1980) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(80)90021-7 · Cited by 4,514
Neurotransmitters and neuromodulators in the basal ganglia
Graybiel, A. M. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90104-i · Cited by 1,576
The neostriatal mosaic: multiple levels of compartmental organization
Gerfen, C. R. (1992) · Trends in Neurosciences · doi:10.1016/0166-2236(92)90355-c · Cited by 1,471
The control of firing pattern in nigral dopamine neurons: burst firing
Grace, A., & Bunney, B. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-11-02877.1984 · Cited by 1,346
Catecholamine innervation of the basal forebrain IV. Topography of the dopamine projection to the basal forebrain and neostriatum
Fallon, J. H., & Moore, R. Y. (1978) · The Journal of Comparative Neurology · doi:10.1002/cne.901800310 · Cited by 1,190
The control of firing pattern in nigral dopamine neurons: single spike firing
Grace, A., & Bunney, B. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-11-02866.1984 · Cited by 862

Show all 62 references

Research works printed but not linked: 2

Bjo ¨rklund A, Lindvall O (1984) Dopamine systems in the CNS. In: Hand- book of chemical neuroanatomy, Classical transmitters in the CNS, Part I (Bjo ¨rklund A, Ho ¨kfelt T, eds), pp 55-112. Amsterdam: Elsevier.
Gerfen CR, Wilson CJ (1996) The basal ganglia. In: Handbook of chem- ical anatomy, integrated systems in the CNS, Part III (Swanson LW, Bjo ¨rkulnd A, Ho ¨kfelt T, eds), pp 371-468. Amsterdam: Elsevier.

Sorted by citations

Dopamine neuron systems in the brain: An update
Björklund, A., & Dunnett, S. B. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.03.006 · Cited by 1,777
Selective neuronal vulnerability in Parkinson disease
Surmeier, D. J., Obeso, J. A., & Halliday, G. M. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.178 · Cited by 1,116
Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum
Matsuda, W., Furuta, T., Nakamura, K. C., Hioki, H., Fujiyama, F., Arai, R., & Kaneko, T. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4029-08.2009 · Cited by 865
Functional Neuroanatomy of the Basal GangliaPreprint
Lanciego, J. L., Luquin, N., & Obeso, J. A. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a009621 · Cited by 981
Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications
Olanow, C. W., Obeso, J. A., & Stocchi, F. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70521-x · Cited by 559
Physiology and pharmacology of striatal neurons
Kreitzer, A. C. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135422 · Cited by 530
Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix Compartments
Crittenden, J. R., & Graybiel, A. M. (2011) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2011.00059 · Cited by 470
Cholinergic interneuron characteristics and nicotinic properties in the striatum
Zhou, F., Wilson, C. J., & Dani, J. A. (2002) · Journal of Neurobiology · doi:10.1002/neu.10150 · Cited by 465
Living on the edge with too many mouths to feed: Why dopamine neurons die
Bolam, J. P., & Pissadaki, E. K. (2012) · Movement Disorders · doi:10.1002/mds.25135 · Cited by 439
Neuroanatomical localization of an internal clock: A functional link between mesolimbic, nigrostriatal, and mesocortical dopaminergic systems
Meck, W. H. (2006) · Brain Research · doi:10.1016/j.brainres.2006.06.031 · Cited by 369
The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors
Root, D. H., Meléndez, R. I., Záborszky, L., & Napier, T. C. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.03.005 · Cited by 359
A Corticostriatal Path Targeting Striosomes Controls Decision-Making under Conflict
Friedman, A., Homma, D., Gibb, L. G., Amemori, K.-I., Rubin, S. J., Hood, A. S., Riad, M. H., & Graybiel, A. M. (2015) · Cell · doi:10.1016/j.cell.2015.04.049 · Cited by 309
Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP111-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Song, D. D., Shults, C. W., Sisk, A., Rockenstein, E. M., & Masliah, E. (2003) · Experimental Neurology · doi:10.1016/s0014-4886(03)00342-x · Cited by 301
Space, time and dopamine
Arbuthnott, G. W., & Wickens, J. R. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.12.003 · Cited by 287
Exclusive and common targets of neostriatofugal projections of rat striosome neurons: a single neuron-tracing study using a viral vector
Fujiyama, F., Sohn, J., Nakano, T., Furuta, T., Nakamura, K., Matsuda, W., & Kaneko, T. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07564.x · Cited by 294
Ageing and neurodegenerative diseases
Hung, C.-W., Chen, Y., Hsieh, W.-L., Chiou, S., & Kao, C.-L. (2010) · Ageing Research Reviews · doi:10.1016/j.arr.2010.08.006 · Cited by 257
Classification of midbrain dopamine neurons using single-cell gene expression profiling approaches
Poulin, J.-F., Gaertner, Z., Moreno-Ramos, O. A., & Awatramani, R. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.01.004 · Cited by 238
Midbrain Dopamine Neurons: Projection Target Determines Action Potential Duration and Dopamine D 2 Receptor Inhibition
Margolis, E. B., Mitchell, J., Ishikawa, J., Hjelmstad, G. O., & Fields, H. L. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1526-08.2008 · Cited by 239
Wave-like dopamine dynamics as a mechanism for spatiotemporal credit assignment
Hamid, A., Frank, M. J., & Moore, C. I. (2021) · Cell · doi:10.1016/j.cell.2021.03.046 · Cited by 222
A half century of experimental neuroanatomical tracing
Lanciego, J. L., & Wouterlood, F. G. (2011) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2011.07.001 · Cited by 215
Striatal and extrastriatal dopamine in the basal ganglia: An overview of its anatomical organization in normal and Parkinsonian brains
Smith, Y., & Villalba, R. M. (2008) · Movement Disorders · doi:10.1002/mds.22027 · Cited by 194
Cholinergic interneurons in the dorsal and ventral striatum: anatomical and functional considerations in normal and diseased conditions
Gonzales, K. K., & Smith, Y. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12762 · Cited by 175
Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon
McElvain, L. E., Chen, Y., Moore, J. D., Brigidi, G. S., Bloodgood, B. L., Lim, B. K., Costa, R. M., & Kleinfeld, D. (2021) · Neuron · doi:10.1016/j.neuron.2021.03.017 · Cited by 166
Endogenous Hydrogen Peroxide Regulates the Excitability of Midbrain Dopamine Neurons via ATP-Sensitive Potassium Channels
Avshalumov, M. V., Chen, B. T., Koós, T. Z., Tepper, J. M., & Rice, M. E. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4701-04.2005 · Cited by 167
Inputs to the Dorsal Striatum of the Mouse Reflect the Parallel Circuit Architecture of the Forebrain
Pan, W. X., Mao, T., & Dudman, J. T. (2010) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2010.00147 · Cited by 150
The ability of the mesocortical dopamine system to operate in distinct temporal modes
Lapish, C. C., Kroener, S., Durstewitz, D., Lavı́n, A., & Seamans, J. K. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0527-8 · Cited by 153
BASAL GANGLIA PATHOLOGY IN SCHIZOPHRENIA: DOPAMINE CONNECTIONS and ANOMALIES
Pérez‐Costas, E., Meléndez‐Ferro, M., & Roberts, R. C. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06604.x · Cited by 149
Dynamic regulation of midbrain dopamine neuron activity: intrinsic, synaptic, and plasticity mechanisms
Morikawa, H., & Paladini, C. A. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.023 · Cited by 159
The external globus pallidus: progress and perspectives
Hegeman, D. J., Hong, E. S., Hernández, V. M., & Chan, C. S. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13196 · Cited by 157
Learning from Action: Reconsidering Movement Signaling in Midbrain Dopamine Neuron Activity
Coddington, L. T., & Dudman, J. T. (2019) · Neuron · doi:10.1016/j.neuron.2019.08.036 · Cited by 150
Long-range projection neurons of the mouse ventral tegmental area: a single-cell axon tracing analysis
Aransay, A., Rodríguez-López, C., García‐Amado, M., Clascá, F., & Prensa, L. (2015) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2015.00059 · Cited by 153
The multilingual nature of dopamine neurons
Trudeau, L., Hnasko, T. S., Wallén‐Mackenzie, Å., Morales, M., Rayport, S., & Sulzer, D. L. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63425-2.00006-4 · Cited by 138
Spontaneous firing and evoked pauses in the tonically active cholinergic interneurons of the striatum
Goldberg, J. A., & Reynolds, J. N. J. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.067 · Cited by 148
Single-axon tracing and three-dimensional reconstruction of centre médian-parafascicular thalamic neurons in primates
Parent, M., & Parent, A. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20348 · Cited by 136
The fate of striatal dopaminergic neurons in Parkinson's disease and Huntington's chorea
Huot, P., Lévesque, M., & Parent, A. (2006) · Brain · doi:10.1093/brain/awl332 · Cited by 129
Traumatic Brain Injury in Adult Rats Causes Progressive Nigrostriatal Dopaminergic Cell Loss and Enhanced Vulnerability to the Pesticide Paraquat
Hutson, C. B., Lazo, C. R., Mortazavi, F., Giza, C. C., Hovda, D. A., & Chesselet, M. (2011) · Journal of Neurotrauma · doi:10.1089/neu.2010.1723 · Cited by 133
Cholinergic modulation of striatal microcircuits
Abudukeyoumu, N., Hernández-Flores, T., Garcia-Munoz, M., & Arbuthnott, G. W. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.13949 · Cited by 144
Development, wiring and function of dopamine neuron subtypes
Garritsen, O., van Battum, E. Y., Grossouw, L. M., & Pasterkamp, R. J. (2023) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00669-3 · Cited by 128
Extracellular matrix molecules and synaptic plasticity: immunomapping of intracellular and secreted Reelin in the adult rat brain
Ramos‐Moreno, T., Galazo, M. J., Porrero, C., Martínez‐Cerdeño, V., & Clascá, F. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04567.x · Cited by 133
Three-Dimensional Organization of the Recurrent Axon Collateral Network of the Substantia Nigra Pars Reticulata Neurons in the Rat
Mailly, P., Charpier, S., Menetrey, A., & Deniau, J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-12-05247.2003 · Cited by 129
Neural encoding of cocaine‐seeking behavior is coincident with phasic dopamine release in the accumbens core and shell
Owesson‐White, C. A., Ariansen, J., Stuber, G. D., Cleaveland, N. A., Cheer, J. F., Mark Wightman, R., & Carelli, R. M. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06916.x · Cited by 126
Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals?
Wong, Y. C., Luk, K. C., Purtell, K., Burke, S., Stoessl, A. J., Trudeau, L., Yue, Z., Krainc, D., Oertel, W. H., Obeso, J. A., et al. (2019) · Movement Disorders · doi:10.1002/mds.27823 · Cited by 126
Distinct patterns of neuronal inputs and outputs of the juxtaparaventricular and suprafornical regions of the lateral hypothalamic area in the male rat
Hahn, J. D., & Swanson, L. W. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.02.002 · Cited by 123
Somatodendritic dopamine release: recent mechanistic insights
Rice, M. E., & Patel, J. C. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0185 · Cited by 131
The amygdala: securing pleasure and avoiding pain
Fernando, A. B. P., Murray, J. E., & Milton, A. L. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00190 · Cited by 119
Activity of Neurochemically Heterogeneous Dopaminergic Neurons in the Substantia Nigra during Spontaneous and Driven Changes in Brain State
Brown, M. T. C., Henny, P., Bolam, J. P., & Magill, P. J. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4423-08.2009 · Cited by 106
Dopamine Inhibition Differentially Controls Excitability of Substantia Nigra Dopamine Neuron Subpopulations through T-Type Calcium Channels
Evans, R. C., Zhu, M., & Khaliq, Z. M. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.0117-17.2017 · Cited by 103
Dopamine and Acetylcholine, a Circuit Point of View in Parkinson’s Disease
Rizzi, G., & Tan, K. R. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00110 · Cited by 109
Differential striatal spine pathology in Parkinson’s disease and cocaine addiction: A key role of dopamine?
Villalba, R. M., & Smith, Y. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.07.011 · Cited by 97
Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease
Dong, J., Hawes, S., Wu, J., Le, W., & Cai, H. (2021) · Frontiers in Neural Circuits · doi:10.3389/fncir.2021.645287 · Cited by 93
Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins
Luppi, M. P., Azcorra, M., Caronia, G., Poulin, J.-F., Gaertner, Z. A., Gatica, S., Moreno-Ramos, O. A., Nouri, N., Dubois, M., Ma, Y. C., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109975 · Cited by 103
Pathophysiology of Tourette's syndrome: striatal pathways revisited
Saka, E., & Graybiel, A. M. (2003) · Brain and Development · doi:10.1016/s0387-7604(03)90002-7 · Cited by 92
Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout
Giguère, N., Delignat‐Lavaud, B., Herborg, F., Voisin, A. N., Li, Y., Jacquemet, V., Anand‐Srivastava, M. B., Gether, U., Giros, B., & Trudeau, L. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008352 · Cited by 88
Regulation of autophagy by mitochondrial phospholipids in health and diseases
Hsu, P., & Shi, Y. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.08.003 · Cited by 86
The Degeneration of Dopamine Neurons in Parkinson's Disease: Insights from Embryology and Evolution of the Mesostriatocortical System
Vernier, P., Moret, F., Callier, S., Snapyan, M., Wersinger, C., & Sidhu, A. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1332.015 · Cited by 82
Selective neuronal vulnerability in Parkinson's disease
González‐Rodríguez, P., Zampese, E., & Surmeier, D. J. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2020.02.005 · Cited by 80
Patterns of axonal branching of neurons of the substantia nigra pars reticulata and pars lateralis in the rat
Cebrián, C., Parent, A., & Prensa, L. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20741 · Cited by 80
The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra
Davis, M. I., Crittenden, J. R., Feng, A. Y., Kupferschmidt, D. A., Naydenov, A. V., Stella, N., Graybiel, A. M., & Lovinger, D. M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191436 · Cited by 72
Glutamate Corelease Promotes Growth and Survival of Midbrain Dopamine Neurons
Fortin, G. M., Bourque, M.-J., Méndez, J. A. T., Leo, D., Nordenankar, K., Birgner, C., Arvidsson, E., Rymar, V. V., Bérubé‐Carrière, N., Claveau, A.-M., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1939-12.2012 · Cited by 77
Localization of immunoreactivity for Deleted in Colorectal Cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents
Osborne, P. B., Halliday, G. M., Cooper, H. M., & Keast, J. R. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.11.043 · Cited by 77
Striosome-based map of the mouse striatum that is conformable to both cortical afferent topography and uneven distributions of dopamine D1 and D2 receptor-expressing cells
Miyamoto, Y., Katayama, S., Shigematsu, N., Nishi, A., & Fukuda, T. (2018) · Brain Structure and Function · doi:10.1007/s00429-018-1749-3 · Cited by 75
Respiratory deficits in a rat model of Parkinson’s disease
Cavalleri, M. T., Barna, B. F., Alves-dos-Santos, L., Britto, L. R. G., Chiavegatto, S., Moreira, T. S., & Takakura, A. C. T. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.03.048 · Cited by 76
Compartmental function and modulation of the striatum
Prager, E. M., & Plotkin, J. L. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24522 · Cited by 76
Distributional Reinforcement Learning in the Brain
Lowet, A. S., Qiao, Z., Matias, S., Drugowitsch, J., & Uchida, N. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.09.004 · Cited by 75
Sex-dependent effects of periadolescent exposure to the cannabinoid agonist CP-55,940 on morphine self-administration behaviour and the endogenous opioid system
Fernández, J. M. B., Fernández, B., Higuera‐Matas, A., Miguéns, M., Viveros, M., Garcı́a-Lecumberri, C., & Ambrosio, E. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.01.006 · Cited by 72
Effect of intrastriatal 6-OHDA lesion on dopaminergic innervation of the rat cortex and globus pallidus
Debeir, T., Ginestet, L., François, C., Laurens, S., Martel, J., Chopin, P., Marien, M. R., Colpaert, F. C., & Raisman‐Vozari, R. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.01.007 · Cited by 73
Phasic activation of substantia nigra and the ventral tegmental area by chemical stimulation of the superior colliculus: an electrophysiological investigation in the rat
Coizet, V., Comoli, E., Westby, G. W. M., & Redgrave, P. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02415.x · Cited by 70
Morphological changes of glutamatergic synapses in animal models of Parkinson’s disease
Villalba, R. M., Mathai, A., & Smith, Y. (2015) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2015.00117 · Cited by 70
Dopamine dynamics and cocaine sensitivity differ between striosome and matrix compartments of the striatum
Salinas, A. G., Davis, M. I., Lovinger, D. M., & Mateo, Y. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.03.049 · Cited by 68
A nitric oxide synthase inhibitor decreases 6-hydroxydopamine effects on tyrosine hydroxylase and neuronal nitric oxide synthase in the rat nigrostriatal pathway
Gomes, M. Z., Raisman‐Vozari, R., & Bel, E. A. D. (2008) · Brain Research · doi:10.1016/j.brainres.2008.01.088 · Cited by 66
The substantia nigra and ventral tegmental dopaminergic neurons from development to degeneration
Fu, Y., Paxinos, G., WATSON, C. R. R., & Halliday, G. M. (2016) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2016.02.001 · Cited by 67
Distribution of GABAergic Interneurons and Dopaminergic Cells in the Functional Territories of the Human Striatum
Bernácer, J., Prensa, L., & Giménez‐Amaya, J. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030504 · Cited by 65
Substantia nigra compacta neurons that innervate the reticular thalamic nucleus in the rat also project to striatum or globus pallidus: Implications for abnormal motor behavior
Anaya-Martı́nez, V., Martı́nez-Marcos, A., Martínez‐Fong, D., Aceves, J., & Erlij, D. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.033 · Cited by 65
Novel aspects of the chemical anatomy of the striatum and its efferents projections
Lévesque, M., Bédard, A., Cossette, M., & Parent, A. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2003.07.001 · Cited by 64
Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication
Rolland, A., Tandé, D., Herrero, M. T., Luquín, M. R., Vázquez‐Claverie, M., Karachi, C., Hirsch, É. C., & François, C. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06220.x · Cited by 62
Agouti-Related Protein Neuron Circuits That Regulate Appetite
Sternson, S. M., & Atasoy, D. (2014) · Neuroendocrinology · doi:10.1159/000369072 · Cited by 64
A single-neuron tracing study of arkypallidal and prototypic neurons in healthy rats
Fujiyama, F., Nakano, T., Matsuda, W., Furuta, T., Udagawa, J., & Kaneko, T. (2015) · Brain Structure and Function · doi:10.1007/s00429-015-1152-2 · Cited by 62
Rapid Dopamine Signaling Differentially Modulates Distinct Microcircuits within the Nucleus Accumbens during Sucrose-Directed Behavior
Cacciapaglia, F., Wightman, R. M., & Carelli, R. M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1340-11.2011 · Cited by 63
Cell and circuit complexity of the external globus pallidus
Courtney, C. D., Pamukcu, A., & Chan, C. S. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01368-7 · Cited by 59
On the Diverse Functions of Electrical Synapses
Vaughn, M. J., & Haas, J. S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.910015 · Cited by 65
Modulation of direct pathway striatal projection neurons by muscarinic M4-type receptors
Hernández-Flores, T., Hernández-González, O., Perez-Ramirez, M. B., Lara‐González, E., Arias-García, M. A., Duhne, M., Pérez‐Burgos, A., Prieto, G. A., Figueroa, A., Galarraga, E., et al. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.09.028 · Cited by 54
NTS-Polyplex: a potential nanocarrier for neurotrophic therapy of Parkinson's disease
Martínez‐Fong, D., Bannon, M. J., Trudeau, L., González-Barrios, J. A., Arango-Rodríguez, M. L., Hernández‐Chan, N. G., Reyes-Corona, D., Armendáriz‐Borunda, J., & Navarro-Quiroga, I. (2012) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2012.02.009 · Cited by 56
Control of the Subthalamic Innervation of the Rat Globus Pallidus by D2/3and D4Dopamine Receptors
Hernández, A., Ibáñez-Sandoval, O., Sierra, A., Valdiosera, R., Tapia, D., Anaya, V., Galarraga, E., Bargas, J., & Aceves, J. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00664.2006 · Cited by 55
Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease
Reyes, S., Fu, Y., Double, K. L., Cottam, V., Thompson, L. H., Kirik, D., Paxinos, G., WATSON, C. R. R., Cooper, H. M., & Halliday, G. M. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.07.019 · Cited by 55
The synaptic function of parkin
Sassone, J., Serratto, G. M., Valtorta, F., Silani, V., Passafaro, M., & Ciammola, A. (2017) · Brain · doi:10.1093/brain/awx006 · Cited by 52
KATP Channel Openers Facilitate Glutamate Uptake by GluTs in Rat Primary Cultured Astrocytes
Sun, X., Zeng, X., Zhou, F., Cui-ping, D., Ding, J., & Hu, G. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301501 · Cited by 51
Establishing causality for dopamine in neural function and behavior with optogenetics
Steinberg, E. E., & Janak, P. H. (2012) · Brain Research · doi:10.1016/j.brainres.2012.09.036 · Cited by 56
Advances in the study of cholinergic circuits in the central nervous system
He, G., Yang, L., Deng, H., & Zuo, H. (2023) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51920 · Cited by 49
Organization of midbrain dopamine systems and the pathophysiology of Parkinson's disease
Moore, R. Y. (2003) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(03)00063-4 · Cited by 50
Subcellular and regional localization of mRNA translation in midbrain dopamine neurons
Hobson, B. D., Kong, L., Angelo, M. F., Lieberman, O. J., Mosharov, E. V., Herzog, É., Sulzer, D., & Sims, P. A. (2022) · Cell Reports · doi:10.1016/j.celrep.2021.110208 · Cited by 49
Alcohol Stimulates the Release of Dopamine in the Ventral Pallidum but not in the Globus Pallidus: A Dual-Probe Microdialysis Study
Meléndez, R. I., Rodd, Z. A., McBride, W. J., & Murphy, J. M. (2002) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300081 · Cited by 49
Expression of D4 dopamine receptors in striatonigral and striatopallidal neurons in the rat striatum
Rivera, A., Trias, S., Peñafiel, A., Narváez, J. Á., Dı́az-Cabiale, Z., Moratalla, R., & de la Calle, A. (2003) · Brain Research · doi:10.1016/s0006-8993(03)03328-6 · Cited by 48
Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development
Brignani, S., Raj, D. D. A., Schmidt, E. R. E., Düdükcü, Ö., Adolfs, Y., Ruiter, A. A. D., Rybiczka-Tešulov, M., Verhagen, M. G., van der Meer, C., Broekhoven, M. H., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.05.037 · Cited by 46
Ultrastructural immunocytochemical localization of the dopamine D2 receptor and tyrosine hydroxylase in the rat ventral pallidum
Mengual, E., & Pickel, V. M. (2001) · Synapse · doi:10.1002/syn.10033 · Cited by 47
Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin
Matsui, A., & Alvarez, V. A. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.05.076 · Cited by 46
A cadherin‐based code for the divisions of the mouse basal ganglia
Hertel, N., Krishna‐K, Nuernberger, M., & Redies, C. (2008) · The Journal of Comparative Neurology · doi:10.1002/cne.21696 · Cited by 46
Segregation of dopamine and glutamate release sites in dopamine neuron axons: regulation by striatal target cells
Fortin, G. M., Ducrot, C., Giguère, N., Kouwenhoven, W. M., Bourque, M.-J., Pacelli, C., Varaschin, R. K., Brill, M., Singh, S., Wiseman, P. W., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201800713rr · Cited by 45
Neuronal Subset-Specific Migration and Axonal Wiring Mechanisms in the Developing Midbrain Dopamine System
Brignani, S., & Pasterkamp, R. J. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00055 · Cited by 47
Relationship between axonal collateralization and neuronal degeneration in basal ganglia
Parent, M., & Parent, A. (2006) · Springer eBooks · doi:10.1007/978-3-211-45295-0_14 · Cited by 44
Striatal Cholinergic Interneurons Modulate Spike-Timing in Striosomes and Matrix by an Amphetamine-Sensitive Mechanism
Crittenden, J. R., Lacey, C. J., Weng, F., Garrison, C. E., Gibson, D. J., Lin, Y., & Graybiel, A. M. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00020 · Cited by 42

Authors: Prensa, L., & Parent, A.
Affiliations: Université Laval (CA)
ORCID: Prensa, Lucı́a
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 2001-09-15
Volume: 21
Issue: 18
Pages: 7247-7260
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.21-18-07247.2001
PMC: PMC6762986
OpenAlex: W1925686653
Cited by: 238
References: 62
Citations by year: 2026: 5 · 2025: 6 · 2024: 8 · 2023: 10 · 2022: 8 · 2021: 11 · 2020: 10 · 2019: 8 · 2018: 12 · 2017: 14 · 2016: 16 · 2015: 13 · 2014: 8 · 2013: 6 · 2012: 15
FWCI: 4.74
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Neuroscience (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Medical Research Council Canada
Medical Research Council
Topics: Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: nigrostriatal pathway, substantia nigra pars compacta, substantia nigra pars reticulata, ventral tegmental area, retrorubral field, striosomes, striatal matrix, axonal arborization, striatal projections, subthalamic nucleus, globus pallidus, amygdala, ventral pallidum, mu-opioid receptor
MeSH terms: Animals, Axons, Biotin, Corpus Striatum, Dextrans, Female, Immunohistochemistry, Male, Neural Pathways, Neurons, Substantia Nigra, Organelles, Rats, Sprague-Dawley, Receptors, Opioid, mu, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Nigrostriatal Pathway in the Rat: A Single-Axon Study of the Relationship between Dorsal and Ventral Tier Nigral Neurons and the Striosome/Matrix Striatal Compartments

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks