Learning from Action: Reconsidering Movement Signaling in Midbrain Dopamine Neuron Activity
Open accessAbstract
Animals infer when and where a reward is available from experience with informative sensory stimuli and their own actions. In vertebrates, this is thought to depend upon the release of dopamine from midbrain dopaminergic neurons. Studies of the role of dopamine have focused almost exclusively on their encoding of informative sensory stimuli; however, many dopaminergic neurons are active just prior to movement initiation, even in the absence of sensory stimuli. How should current frameworks for understanding the role of dopamine incorporate these observations? To address this question, we review recent anatomical and functional evidence for action-related dopamine signaling. We conclude by proposing a framework in which dopaminergic neurons encode subjective signals of action initiation to solve an internal credit assignment problem.
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DA neurotransmission is essential for diverse behavioral outputs, including motivation, cognition, reward learning, decision making, salience attribution, and voluntary motor control.
“DA neurotransmission is essential for diverse behavioral outputs, including motivation, cognition, reward learning, decision making, salience attribution, and voluntary motor control [121–127].”
From Adolescent nicotine exposure and persistent neurocircuitry changes: unveiling lifelong psychiatric risks (2025) · cites this paper as [125]
Cites
Learning representations by back-propagating errors
Rumelhart, D. E., Hinton, G. E., & Williams, R. J. (1986) · Nature · doi:10.1038/323533a0 · Cited by 31,892 · see citing works
Reinforcement Learning: An Introduction
Sutton, R. S., & Barto, A. G. (1998) · IEEE Transactions on Neural Networks · doi:10.1109/tnn.1998.712192 · Cited by 27,225 · see citing works
Reinforcement Learning: An Introduction
Sutton, R. S., & Barto, A. (2005) · IEEE Transactions on Neural Networks · doi:10.1109/tnn.2004.842673 · Cited by 25,263 · see citing works
A neural substrate of prediction and reward
Schultz, W., Dayan, P., & Montague, P. R. (1997) · Science · doi:10.1126/science.275.5306.1593 · Cited by 9,388 · see citing works
(1982) · Trends in Neurosciences · doi:10.1016/0166-2236(82)90076-5 · Cited by 9,148 · see citing works
Simple Statistical Gradient-Following Algorithms for Connectionist Reinforcement Learning
Williams, R. J. (1992) · Machine Learning · doi:10.1007/bf00992696 · Cited by 7,936 · see citing works
Henry, M. A. (1995) · The Journal of the American Dental Association · doi:10.14219/jada.archive.1995.0108 · Cited by 3,454 · see citing works
Dopamine, learning and motivation.
Wise, R. A. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1406 · Cited by 3,379 · see citing works
Optimal feedback control as a theory of motor coordination
Todorov, E., & Jordan, M. I. (2002) · Nature Neuroscience · doi:10.1038/nn963 · Cited by 3,081 · see citing works
Gerfen, C. R., Engber, T. M., Mahan, L. C., Susel, Z., Chase, T. N., Monsma, F. J., & Sibley, D. R. (1990) · Science · doi:10.1126/science.2147780 · Cited by 2,967 · see citing works
Dopamine in motivational control: rewarding, aversive, and alerting
Bromberg-Martin, E. S., Matsumoto, M., & Hikosaka, O. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.022 · Cited by 2,396 · see citing works
The debate over dopamine’s role in reward: the case for incentive salience
Berridge, K. C. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0578-x · Cited by 2,347 · see citing works
High-Dimensional Continuous Control Using Generalized Advantage Estimation
Schulman, J., Moritz, P., Levine, S., Jordan, M., & Abbeel, P. (2015) · arXiv · doi:10.48550/arxiv.1506.02438 · Cited by 2,103 · see citing works
Modulation of Striatal Projection Systems by Dopamine
Gerfen, C. R., & Surmeier, D. J. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113641 · Cited by 1,700 · see citing works
Neural population dynamics during reaching
Churchland, M. M., Cunningham, J. P., Kaufman, M. T., Foster, J. D., Nuyujukian, P., Ryu, S. I., & Shenoy, K. V. (2012) · Nature · doi:10.1038/nature11129 · Cited by 1,636 · see citing works
Haber, S. N., Fudge, J. L., & McFarland, N. R. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-06-02369.2000 · Cited by 1,610 · see citing works
Goal-directed instrumental action: contingency and incentive learning and their cortical substrates
Balleine, B. W., & Dickinson, A. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00033-1 · Cited by 1,541 · see citing works
The mysterious motivational functions of mesolimbic dopamine
Salamone, J. D., & Correa, M. (2012) · Neuron · doi:10.1016/j.neuron.2012.10.021 · Cited by 1,418 · see citing works
Two types of dopamine neuron distinctly convey positive and negative motivational signals
Matsumoto, M., & Hikosaka, O. (2009) · Nature · doi:10.1038/nature08028 · Cited by 1,378 · see citing works
The control of firing pattern in nigral dopamine neurons: burst firing
Grace, A., & Bunney, B. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-11-02877.1984 · Cited by 1,346 · see citing works
Picciotto, M. R., Zoli, M., Rimondini, R., Léna, C., Marubio, L. M., Pich, E. M., Fuxe, K., & Changeux, J.-P. (1998) · Nature · doi:10.1038/34413 · Cited by 1,320 · see citing works
Schultz, W., Apicella, P., & Ljungberg, T. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-03-00900.1993 · Cited by 1,291 · see citing works
Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning
Tsai, H.-C., Zhang, F., Adamantidis, A., Stuber, G. D., Bonci, A., de Lecea, L., & Deisseroth, K. (2009) · Science · doi:10.1126/science.1168878 · Cited by 1,266 · see citing works
Yin, H. H., Knowlton, B. J., & Balleine, B. W. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03095.x · Cited by 1,226 · see citing works
Whole-Brain Mapping of Direct Inputs to Midbrain Dopamine Neurons
Watabe‐Uchida, M., Zhu, L., Ogawa, S. K., Vamanrao, A., & Uchida, N. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.017 · Cited by 1,221 · see citing works
Surmeier, D. J., Ding, J., Day, M., Wang, Z., & Shen, W. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.03.008 · Cited by 1,203 · see citing works
Neuronal Reward and Decision Signals: From Theories to Data
Schultz, W. (2015) · Physiological Reviews · doi:10.1152/physrev.00023.2014 · Cited by 1,126 · see citing works
Subsecond dopamine release promotes cocaine seeking
Phillips, P. E. M., Stuber, G. D., Heien, M. L. A. V., Wightman, R. M., & Carelli, R. M. (2003) · Nature · doi:10.1038/nature01476 · Cited by 1,113 · see citing works
Dopamine neurons modulate neural encoding and expression of depression-related behaviour
Tye, K. M., Mirzabekov, J. J., Warden, M. R., Ferenczi, E. A., Tsai, H.-C., Finkelstein, J., Kim, S.-Y., Adhikari, A., Thompson, K. R., Andalman, A. S., et al. (2013) · Nature · doi:10.1038/nature11740 · Cited by 1,073 · see citing works
Circuit architecture of VTA dopamine neurons revealed by systematic input-output mapping
Beier, K. T., Steinberg, E. E., DeLoach, K. E., Xie, S., Miyamichi, K., Schwarz, L., Gao, X. J., Kremer, E. J., Malenka, R. C., & Luo, L. (2015) · Cell · doi:10.1016/j.cell.2015.07.015 · Cited by 1,068 · see citing works
Dopamine reward prediction-error signalling: A two-component response
Schultz, W. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2015.26 · Cited by 1,036 · see citing works
A selective role for dopamine in stimulus-reward learning
Flagel, S. B., Clark, J. J., Robinson, T. E., Mayo, L., Czuj, A., Willuhn, I., Akers, C. A., Clinton, S. M., Phillips, P. E. M., & Akil, H. (2011) · Nature · doi:10.1038/nature09588 · Cited by 1,026 · see citing works
Dopamine responses comply with basic assumptions of formal learning theory
Waelti, P., Dickinson, A., & Schultz, W. (2001) · Nature · doi:10.1038/35083500 · Cited by 1,018 · see citing works
Responses of monkey dopamine neurons during learning of behavioral reactions
Ljungberg, T., Apicella, P., & Schultz, W. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.67.1.145 · Cited by 987 · see citing works
(2009) · doi:10.1007/978-3-540-29678-2 · Cited by 900 · see citing works
A causal link between prediction errors, dopamine neurons and learning
Steinberg, E. E., Keiflin, R., Boivin, J. R., Witten, I. B., Deisseroth, K. A., & Janak, P. H. (2013) · Nature Neuroscience · doi:10.1038/nn.3413 · Cited by 879 · see citing works
Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking
Stuber, G. D., Sparta, D. R., Stamatakis, A. M., van Leeuwen, W. A., Hardjoprajitno, J. E., Cho, S., Tye, K. M., Kempadoo, K. A., Zhang, F., Deisseroth, K., et al. (2011) · Nature · doi:10.1038/nature10194 · Cited by 878 · see citing works
Matsuda, W., Furuta, T., Nakamura, K. C., Hioki, H., Fujiyama, F., Arai, R., & Kaneko, T. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4029-08.2009 · Cited by 865 · see citing works
Molecular logic of neocortical projection neuron specification, development and diversity
Greig, L. C., Woodworth, M. B., Galazo, M. J., Padmanabhan, H., & Macklis, J. D. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3586 · Cited by 863 · see citing works
The control of firing pattern in nigral dopamine neurons: single spike firing
Grace, A., & Bunney, B. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-11-02866.1984 · Cited by 862 · see citing works
Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons
Threlfell, S., Lalic, T., Platt, N. J., Jennings, K. A., Deisseroth, K., & Cragg, S. J. (2012) · Neuron · doi:10.1016/j.neuron.2012.04.038 · Cited by 845 · see citing works
Mesolimbic dopamine signals the value of work
Hamid, A., Pettibone, J. R., Mabrouk, O. S., Hetrick, V. L., Schmidt, R., Weele, C. M. V., Kennedy, R. T., Aragona, B. J., & Berke, J. D. (2015) · Nature Neuroscience · doi:10.1038/nn.4173 · Cited by 815 · see citing works
Motor Cortical Representation of Speed and Direction During Reaching
Moran, D. W., & Schwartz, A. B. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.82.5.2676 · Cited by 813 · see citing works
Sign-tracking : the stimulus-reinforcer relation and directed action
Hearst, E. S., & Jenkins, H. M. (1974) · Medical Entomology and Zoology · Cited by 812 · see citing works
Reward and aversion in a heterogeneous midbrain dopamine system
Lammel, S., Lim, B. K., & Malenka, R. C. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.03.019 · Cited by 804 · see citing works
Intact-brain analyses reveal distinct information carried by SNc dopamine subcircuits
Lerner, T. N., Shilyansky, C., Davidson, T. J., Evans, K. E., Beier, K. T., Zalocusky, K. A., Crow, A. K., Malenka, R. C., Luo, L., Tomer, R., et al. (2015) · Cell · doi:10.1016/j.cell.2015.07.014 · Cited by 794 · see citing works
The short-latency dopamine signal: a role in discovering novel actions?
Redgrave, P., & Gurney, K. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn2022 · Cited by 762 · see citing works
Dopaminergic modulation of synaptic transmission in cortex and striatum
Tritsch, N. X., & Sabatini, B. L. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.023 · Cited by 756 · see citing works
Dopamine operates as a subsecond modulator of food seeking
Roitman, M. F., Stuber, G. D., Phillips, P. E. M., Wightman, R. M., & Carelli, R. M. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3823-03.2004 · Cited by 718 · see citing works
Dissociable dopamine dynamics for learning and motivation
Mohebi, A., Pettibone, J. R., Hamid, A., Wong, J.-M. T., Vinson, L. T., Patriarchi, T., Tian, L., Kennedy, R. T., & Berke, J. D. (2019) · Nature · doi:10.1038/s41586-019-1235-y · Cited by 714 · see citing works
Associative learning mediates dynamic shifts in dopamine signaling in the nucleus accumbens
Day, J. J., Roitman, M. F., Wightman, R. M., & Carelli, R. M. (2007) · Nature Neuroscience · doi:10.1038/nn1923 · Cited by 710 · see citing works
From prediction error to incentive salience: mesolimbic computation of reward motivation.
Berridge, K. C. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.07990.x · Cited by 700 · see citing works
Solving the Distal Reward Problem through Linkage of STDP and Dopamine Signaling
Izhikevich, E. M. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhl152 · Cited by 664 · see citing works
Gremel, C. M., & Costa, R. M. (2013) · Nature Communications · doi:10.1038/ncomms3264 · Cited by 618 · see citing works
Start/stop signals emerge in nigrostriatal circuits during sequence learning
Jin, X., & Costa, R. M. (2010) · Nature · doi:10.1038/nature09263 · Cited by 611 · see citing works
Roesch, M. R., Calu, D. J., & Schoenbaum, G. (2007) · Nature Neuroscience · doi:10.1038/nn2013 · Cited by 597 · see citing works
Rapid signalling in distinct dopaminergic axons during locomotion and reward
Howe, M. W., & Dombeck, D. A. (2016) · Nature · doi:10.1038/nature18942 · Cited by 597 · see citing works
Activity of striatal neurons reflects dynamic encoding and recoding of procedural memories
Barnes, T. D., Kubota, Y., Hu, D., Jin, D. Z., & Graybiel, A. M. (2005) · Nature · doi:10.1038/nature04053 · Cited by 595 · see citing works
Dopaminergic neurons inhibit striatal output through non-canonical release of GABA
Tritsch, N. X., Ding, J. B., & Sabatini, B. L. (2012) · Nature · doi:10.1038/nature11466 · Cited by 576 · see citing works
Why Don't We Move Faster? Parkinson's Disease, Movement Vigor, and Implicit Motivation
Mazzoni, P., Hristova, A., & Krakauer, J. W. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0264-07.2007 · Cited by 557 · see citing works
Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors
Jennings, J. H., Ung, R. L., Resendez, S. L., Stamatakis, A. M., Taylor, J. G., Huang, J. H., Veleta, K., Kantak, P. A., Aita, M., Shilling-Scrivo, K. V., et al. (2015) · Cell · doi:10.1016/j.cell.2014.12.026 · Cited by 550 · see citing works
Dopamine neuron activity before action initiation gates and invigorates future movements
da Silva, J. A., Tecuapetla, F., Paixão, V., & Costa, R. M. (2018) · Nature · doi:10.1038/nature25457 · Cited by 550 · see citing works
Midbrain Dopamine Neurons Signal Preference for Advance Information about Upcoming Rewards
Bromberg-Martin, E. S., & Hikosaka, O. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.009 · Cited by 548 · see citing works
Specialized coding of sensory, motor and cognitive variables in VTA dopamine neurons
Engelhard, B., Finkelstein, J., Cox, J., Fleming, W., Jang, H. J., Ornelas, S., Koay, S. A., Thiberge, S. Y., Daw, N. D., Tank, D. W., et al. (2019) · Nature · doi:10.1038/s41586-019-1261-9 · Cited by 544 · see citing works
Winnubst, J., Bas, E., Ferreira, T. A., Wu, Z., Economo, M. N., Edson, P., Arthur, B. J., Bruns, C., Rokicki, K., Schauder, D., et al. (2019) · Cell · doi:10.1016/j.cell.2019.07.042 · Cited by 538 · see citing works
Self-citationA Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System
de Jong, J. W., Afjei, S. A., Dorocic, I. P., Peck, J. R., Liu, C. J., Kim, C. K., Tian, L., Deisseroth, K. A., & Lammel, S. (2018) · Neuron · doi:10.1016/j.neuron.2018.11.005 · Cited by 506 · see citing works
Ambroggi, F., Ishikawa, A., Fields, H. L., & Nicola, S. M. (2008) · Neuron · doi:10.1016/j.neuron.2008.07.004 · Cited by 488 · see citing works
Glutamatergic Afferents of the Ventral Tegmental Area in the Rat
Geisler, S., Derst, C., Veh, R. W., & Zahm, D. S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0012-07.2007 · Cited by 486 · see citing works
A synaptic threshold mechanism for computing escape decisions
Evans, D. A., Stempel, A. V., Vale, R., Ruehle, S., Lefler, Y., & Branco, T. (2018) · Nature · doi:10.1038/s41586-018-0244-6 · Cited by 449 · see citing works
Varazzani, C., San‐Galli, A., Gilardeau, S., & Bouret, S. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0454-15.2015 · Cited by 446 · see citing works
Coordinated and compartmentalized neuromodulation shapes sensory processing in Drosophila
Cohn, R., Morantte, I., & Ruta, V. (2015) · Cell · doi:10.1016/j.cell.2015.11.019 · Cited by 430 · see citing works
Pan, W.-X., Schmidt, R., Wickens, J. R., & Hyland, B. I. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1478-05.2005 · Cited by 429 · see citing works
Zweifel, L. S., Parker, J. G., Lobb, C. J., Rainwater, A., Wall, V. Z., Fadok, J. P., Darvas, M., Kim, M. J., Mizumori, S. J. Y., Paladini, C. A., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813415106 · Cited by 426 · see citing works
Basal ganglia contributions to motor control: a vigorous tutor
Turner, R. S., & Desmurget, M. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.08.022 · Cited by 422 · see citing works
Yin, H. H., Ostlund, S. B., & Balleine, B. W. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06422.x · Cited by 416 · see citing works
Prefrontal cortex output circuits guide reward seeking through divergent cue encoding
Otis, J. M., Namboodiri, V. M. K., Matan, A. M., Voets, E. S., Mohorn, E. P., Kosyk, O., McHenry, J. A., Robinson, J. E., Resendez, S. L., Rossi, M. A., et al. (2017) · Nature · doi:10.1038/nature21376 · Cited by 412 · see citing works
Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo
Hnasko, T. S., Chuhma, N., Zhang, H., Goh, G. Y., Sulzer, D., Palmiter, R. D., Rayport, S., & Edwards, R. H. (2010) · Neuron · doi:10.1016/j.neuron.2010.02.012 · Cited by 405 · see citing works
Olds, J. (1958) · Science · doi:10.1126/science.127.3294.315 · Cited by 404 · see citing works
Palmiter, R. D. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1417.003 · Cited by 375 · see citing works
Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties
Saunders, B. T., Richard, J. M., Margolis, E. B., & Janak, P. H. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0191-4 · Cited by 365 · see citing works
Midbrain dopamine neurons control judgment of time
Soares, S., Atallah, B. V., & Paton, J. J. (2016) · Science · doi:10.1126/science.aah5234 · Cited by 362 · see citing works
Romo, R., & Schultz, W. (1990) · Journal of Neurophysiology · doi:10.1152/jn.1990.63.3.592 · Cited by 353 · see citing works
Reward and choice encoding in terminals of midbrain dopamine neurons depends on striatal target
Parker, N. F., Cameron, C. M., Taliaferro, J. P., Lee, J., Choi, J. Y., Davidson, T. J., Daw, N. D., & Witten, I. B. (2016) · Nature Neuroscience · doi:10.1038/nn.4287 · Cited by 340 · see citing works
Schultz, W., & Romo, R. (1990) · Journal of Neurophysiology · doi:10.1152/jn.1990.63.3.607 · Cited by 334 · see citing works
Deschênes, M., Bourassa, J., & Pinault, D. (1994) · Brain Research · doi:10.1016/0006-8993(94)91974-7 · Cited by 326 · see citing works
A dual operator view of habitual behavior reflecting cortical and striatal dynamics
Smith, K. S., & Graybiel, A. M. (2013) · Neuron · doi:10.1016/j.neuron.2013.05.038 · Cited by 324 · see citing works
Dopamine Is Required for the Neural Representation and Control of Movement Vigor
Panigrahi, B., Martin, K. A., Li, Y., Graves, A. R., Vollmer, A., Olson, L., Mensh, B. D., Karpova, A. Y., & Dudman, J. T. (2015) · Cell · doi:10.1016/j.cell.2015.08.014 · Cited by 315 · see citing works
Self-citationGlutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens
Tecuapetla, F., Patel, J. C., Xenias, H., English, D., Tadros, I., Shah, F., Berlin, J., Deisseroth, K., Rice, M. E., Tepper, J. M., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.0265-10.2010 · Cited by 310 · see citing works
Dopamine neurons share common response function for reward prediction error
Eshel, N., Tian, J., Bukwich, M., & Uchida, N. (2016) · Nature Neuroscience · doi:10.1038/nn.4239 · Cited by 306 · see citing works
Hierarchical Control of Dopamine Neuron-Firing Patterns by Nicotinic Receptors
Mameli-Engvall, M., Evrard, A., Pons, S., Maskos, U., Svensson, T. H., Changeux, J.-P., & Faure, P. (2006) · Neuron · doi:10.1016/j.neuron.2006.05.007 · Cited by 296 · see citing works
Opponent and bidirectional control of movement velocity in the basal ganglia
Yttri, E. A., & Dudman, J. T. (2016) · Nature · doi:10.1038/nature17639 · Cited by 291 · see citing works
Self-citationWhat, If, and When to Move: Basal Ganglia Circuits and Self-Paced Action Initiation
Klaus, A., Alves da Silva, J., & Costa, R. M. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-072116-031033 · Cited by 284 · see citing works
The basal ganglia: from motor commands to the control of vigor
Dudman, J. T., & Krakauer, J. W. (2016) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2016.02.005 · Cited by 282 · see citing works
Self-citationKita, T., & Kita, H. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5717-11.2012 · Cited by 276 · see citing works
Dopamine neurons encode performance error in singing birds
Gadagkar, V., Puzerey, P. A., Chen, R., Baird-Daniel, E., Farhang, A., & Goldberg, J. H. (2016) · Science · doi:10.1126/science.aah6837 · Cited by 270 · see citing works
Corbett, D., & Wise, R. A. (1980) · Brain Research · doi:10.1016/0006-8993(80)90666-6 · Cited by 264 · see citing works
Yan, Z., Song, W., & Surmeier, D. J. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.77.2.1003 · Cited by 259 · see citing works
Dopamine Neuron-Specific Optogenetic Stimulation in Rhesus Macaques
Stauffer, W. R., Lak, A., Yang, A., Borel, M., Paulsen, O., Boyden, E. S., & Schultz, W. (2016) · Cell · doi:10.1016/j.cell.2016.08.024 · Cited by 256 · see citing works
Similar roles of substantia nigra and ventral tegmental dopamine neurons in reward and aversion
Ilango, A., Kesner, A. J., Keller, K. L., Stuber, G. D., Bonci, A., & Ikemoto, S. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1703-13.2014 · Cited by 255 · see citing works
Zener, K. (1937) · The American Journal of Psychology · doi:10.2307/1416644 · Cited by 242 · see citing works
Prensa, L., & Parent, A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-18-07247.2001 · Cited by 238 · see citing works
Dopamine Modulates Release from Corticostriatal Terminals
Bamford, N. S., Robinson, S., Palmiter, R. D., Joyce, J. A., Moore, C., & Meshul, C. K. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2891-04.2004 · Cited by 238 · see citing works
Yun, I. A., Wakabayashi, K. T., Fields, H. L., & Nicola, S. M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5282-03.2004 · Cited by 238 · see citing works
Action initiation shapes mesolimbic dopamine encoding of future rewards
Syed, E. C. J., Grima, L. L., Magill, P. J., Bogacz, R., Brown, P., & Walton, M. E. (2015) · Nature Neuroscience · doi:10.1038/nn.4187 · Cited by 232 · see citing works
Dopaminergic Modulation of Glutamate Release in Striatum as Measured by Microdialysis
Yamamoto, B. K., & Davy, S. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb10048.x · Cited by 228 · see citing works
Independence of Movement Preparation and Movement Initiation
Haith, A. M., Pakpoor, J., & Krakauer, J. W. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.3245-15.2016 · Cited by 225 · see citing works
A basal ganglia circuit for evaluating action outcomes
Stephenson‐Jones, M., Yu, K., Ahrens, S., Tucciarone, J., van Huijstee, A. N., Mejia, L. A., Penzo, M. A., Tai, L.-H., Wilbrecht, L., & Li, B. (2016) · Nature · doi:10.1038/nature19845 · Cited by 217 · see citing works
Kishida, K. T., Sáez, I., Lohrenz, T. M., Witcher, M. R., Laxton, A. W., Tatter, S. B., White, J. P., Ellis, T. L., Phillips, P. E. M., & Montague, P. R. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1513619112 · Cited by 216 · see citing works
Brief optogenetic inhibition of dopamine neurons mimics endogenous negative reward prediction errors
Chang, C. Y., Esber, G. R., Marrero-Garcia, Y., Yau, H., Bonci, A., & Schoenbaum, G. M. (2015) · Nature Neuroscience · doi:10.1038/nn.4191 · Cited by 211 · see citing works
A VTA GABAergic Neural Circuit Mediates Visually Evoked Innate Defensive Responses
Zhou, Z., Liu, X., Chen, S., Zhang, Z., Liu, Y., Montardy, Q., Tang, Y., Wei, P., Liu, N., Li, L., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.027 · Cited by 211 · see citing works
The timing of action determines reward prediction signals in identified midbrain dopamine neurons
Coddington, L. T., & Dudman, J. T. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0245-7 · Cited by 206 · see citing works
Self-citationNicola, S. M., Yun, I. A., Wakabayashi, K. T., & Fields, H. L. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00657.2003 · Cited by 196 · see citing works
The algorithmic anatomy of model-based evaluation
Daw, N. D., & Dayan, P. (2014) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2013.0478 · Cited by 195 · see citing works
Dodson, P. D., Dreyer, J. K., Jennings, K. A., Syed, E. C. J., Wade‐Martins, R., Cragg, S. J., Bolam, J. P., & Magill, P. J. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1515941113 · Cited by 190 · see citing works
The pars reticulata of the substantia nigra: a window to basal ganglia output
Deniau, J., Mailly, P., Maurice, N., & Charpier, S. (2007) · Progress in brain research · doi:10.1016/s0079-6123(06)60009-5 · Cited by 186 · see citing works
Stuber, G. D., Wightman, R. M., & Carelli, R. M. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.036 · Cited by 168 · see citing works
Habenula Lesions Reveal that Multiple Mechanisms Underlie Dopamine Prediction Errors
Tian, J., & Uchida, N. (2015) · Neuron · doi:10.1016/j.neuron.2015.08.028 · Cited by 165 · see citing works
Evolution of the basal ganglia: Dual‐output pathways conserved throughout vertebrate phylogeny
Stephenson‐Jones, M., Ericsson, J., Robertson, B., & Grillner, S. E. (2012) · The Journal of Comparative Neurology · doi:10.1002/cne.23087 · Cited by 165 · see citing works
Temporally Extended Dopamine Responses to Perceptually Demanding Reward-Predictive Stimuli
Nomoto, K., Schultz, W., Watanabe, T., & Sakagami, M. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4828-09.2010 · Cited by 158 · see citing works
Lévesque, M., Charara, A., Gagnon, S., Parent, A., & Deschênes, M. (1996) · Brain Research · doi:10.1016/0006-8993(95)01333-4 · Cited by 151 · see citing works
Pan, W. X., Mao, T., & Dudman, J. T. (2010) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2010.00147 · Cited by 150 · see citing works
Self-citationChiara, M. L. D., Doets, K., Mundici, D., & van Benthem, J. (1997) · Springer eBooks · doi:10.1007/978-94-017-0487-8 · Cited by 145 · see citing works
Cheer, J. F., Heien, M. L. A. V., Garris, P. A., Carelli, R. M., & Wightman, R. M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509607102 · Cited by 143 · see citing works
Beyond reward prediction errors: the role of dopamine in movement kinematics
Barter, J. W., Li, S., Lu, D., Bartholomew, R. A., Rossi, M. A., Shoemaker, C. T., Salas-Meza, D., Gaidis, E., & Yin, H. H. (2015) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2015.00039 · Cited by 137 · see citing works
Dopamine’s Effects on Corticostriatal Synapses during Reward-Based Behaviors
Bamford, N. S., Wightman, R. M., & Sulzer, D. (2018) · Neuron · doi:10.1016/j.neuron.2018.01.006 · Cited by 137 · see citing works
Overriding Phasic Dopamine Signals Redirects Action Selection during Risk/Reward Decision Making
Stopper, C. M., Tse, M. T. L., Montes, D. R., Wiedman, C. R., & Floresco, S. B. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.033 · Cited by 136 · see citing works
The activity of pars compacta neurons of the monkey substantia nigra in relation to motor activation
Schultz, W., Ruffieux, A., & Aebischer, P. (1983) · Experimental Brain Research · doi:10.1007/bf00237874 · Cited by 136 · see citing works
A Basal Ganglia Circuit Sufficient to Guide Birdsong Learning
Xiao, L., Chattree, G., García‐Oscos, F., Cao, M., Wanat, M. J., & Roberts, T. F. (2018) · Neuron · doi:10.1016/j.neuron.2018.02.020 · Cited by 134 · see citing works
Dynamic Nigrostriatal Dopamine Biases Action Selection
Howard, C. D., Li, H., Geddes, C. E., & Jin, X. (2017) · Neuron · doi:10.1016/j.neuron.2017.02.029 · Cited by 123 · see citing works
Miconi, T. (2017) · eLife · doi:10.7554/elife.20899 · Cited by 123 · see citing works
Dopamine Invigorates Reward Seeking by Promoting Cue-Evoked Excitation in the Nucleus Accumbens
du Hoffmann, J., & Nicola, S. M. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.3492-14.2014 · Cited by 122 · see citing works
NMDA Receptors in Dopaminergic Neurons Are Crucial for Habit Learning
Wang, L. P., Li, F. R., Wang, D., Xie, K., Wang, D., Shen, X., & Tsien, J. Z. (2011) · Neuron · doi:10.1016/j.neuron.2011.10.019 · Cited by 122 · see citing works
Invigoration of Reward Seeking by Cue and Proximity Encoding in the Nucleus Accumbens
McGinty, V. B., Lardeux, S., Taha, S. A., Kim, J. J., & Nicola, S. M. (2013) · Neuron · doi:10.1016/j.neuron.2013.04.010 · Cited by 119 · see citing works
Parent, A., Mackey, A., Smith, Y., & Boucher, R. (1983) · Brain Research Bulletin · doi:10.1016/0361-9230(83)90151-x · Cited by 118 · see citing works
Anderson, M. E., & Turner, R. S. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.66.3.879 · Cited by 117 · see citing works
A cortical motor nucleus drives the basal ganglia-recipient thalamus in singing birds
Goldberg, J. H., & Fee, M. S. (2012) · Nature Neuroscience · doi:10.1038/nn.3047 · Cited by 114 · see citing works
Wassum, K. M., Ostlund, S. B., & Maidment, N. T. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.12.019 · Cited by 112 · see citing works
Central Processing of Itch in the Midbrain Reward Center
Su, X., Chen, M., Yuan, Y., Li, Y., Guo, S.-S., Luo, H., Huang, C., Sun, W., Li, Y., Zhu, M. X., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.03.030 · Cited by 106 · see citing works
Dopaminergic modulation of striatal function and Parkinson’s disease
Zhai, S., Shen, W., Graves, S. M., & Surmeier, D. J. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-01997-y · Cited by 100 · see citing works
Parker, J. G., Zweifel, L. S., Clark, J. J., Evans, S. B., Phillips, P. E. M., & Palmiter, R. D. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007827107 · Cited by 96 · see citing works
Limited Encoding of Effort by Dopamine Neurons in a Cost–Benefit Trade-off Task
Pasquereau, B., & Turner, R. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4619-12.2013 · Cited by 94 · see citing works
Nucleus Accumbens Acetylcholine Receptors Modulate Dopamine and Motivation
Collins, A. L., Aitken, T. J., Greenfield, V. Y., Ostlund, S. B., & Wassum, K. M. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.81 · Cited by 94 · see citing works
Shindou, T., Shindou, M., Watanabe, S., & Wickens, J. R. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.13921 · Cited by 92 · see citing works
Dudman, J. T., & Gerfen, C. R. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-374245-2.00017-6 · Cited by 89 · see citing works
Self-citationDopamine neurons learn relative chosen value from probabilistic rewards
Lak, A., Stauffer, W. R., & Schultz, W. (2016) · eLife · doi:10.7554/elife.18044 · Cited by 87 · see citing works
Coordination of rapid cholinergic and dopaminergic signaling in striatum during spontaneous movement
Howe, M. W., Ridouh, I., Mascaro, A. L. A., Larios, A., Azcorra, M., & Dombeck, D. A. (2019) · eLife · doi:10.7554/elife.44903 · Cited by 84 · see citing works
Temporally and Spatially Distinct Thirst Satiation Signals
Augustine, V., Ebisu, H., Zhao, Y., Lee, S., Ho, B., Mizuno, G. O., Tian, L., & Oka, Y. (2019) · Neuron · doi:10.1016/j.neuron.2019.04.039 · Cited by 82 · see citing works
Interplay of β2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion
Avale, M. E., Fauré, P., Pons, S., Robledo, P., Deltheil, T., David, D. J. P., Gardier, A. M., Maldonado, R. J., Granon, S., Changeux, J., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807635105 · Cited by 78 · see citing works
Puryear, C. B., Kim, M. J., & Mizumori, S. J. Y. (2010) · Behavioral Neuroscience · doi:10.1037/a0018865 · Cited by 69 · see citing works
A Common Optimization Principle for Motor Execution in Healthy Subjects and Parkinsonian Patients
Baraduc, P., Thobois, S., Gan, J., Broussolle, E., & Desmurget, M. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.1482-12.2013 · Cited by 68 · see citing works
Multiple Dopamine Systems: Weal and Woe of DopaminePreprint
Watabe‐Uchida, M., & Uchida, N. (2018) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2018.83.037648 · Cited by 68 · see citing works
Cacciapaglia, F., Wightman, R. M., & Carelli, R. M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1340-11.2011 · Cited by 61 · see citing works
Yuan, L., Liang, T.-Y., Deng, J., & Sun, Y.-G. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1483-18.2018 · Cited by 60 · see citing works
Owesson-White, C., Belle, A. M., Herr, N. R., Peele, J. L., Gowrishankar, P., Carelli, R. M., & Wightman, R. M. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0393-16.2016 · Cited by 55 · see citing works
Dopamine neurons encode errors in predicting movement trigger occurrence
Pasquereau, B., & Turner, R. S. (2014) · Journal of Neurophysiology · doi:10.1152/jn.00401.2014 · Cited by 53 · see citing works
A Proposed Circuit Computation in Basal Ganglia: History‐Dependent Gain
Yttri, E. A., & Dudman, J. T. (2018) · Movement Disorders · doi:10.1002/mds.27321 · Cited by 53 · see citing works
Self-citationDegenerate coding in neural systems
Leonardo, A. (2005) · Journal of Comparative Physiology · doi:10.1007/s00359-005-0026-0 · Cited by 52 · see citing works
Conjunctive Processing of Locomotor Signals by the Ventral Tegmental Area Neuronal Population
Wang, D. V., & Tsien, J. Z. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016528 · Cited by 52 · see citing works
Cue‐evoked encoding of movement planning and execution in the rat nucleus accumbens
Taha, S. A., Nicola, S. M., & Fields, H. L. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.140236 · Cited by 52 · see citing works
The missing, the short, and the long: Levodopa responses and dopamine actions
Albin, R. L., & Leventhal, D. (2017) · Annals of Neurology · doi:10.1002/ana.24961 · Cited by 51 · see citing works
Simon, N. W., Wood, J. T., & Moghaddam, B. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00884.2015 · Cited by 50 · see citing works
Cover, K. K., Gyawali, U., Kerkhoff, W. G., Patton, M. H., Mu, C., White, M. G., Marquardt, A. E., Roberts, B. M., Cheer, J. F., & Mathur, B. N. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.01.044 · Cited by 49 · see citing works
Causation, Action, and Counterfactuals
Pearl, J. (1997) · Springer eBooks · doi:10.1007/978-94-017-0487-8_18 · Cited by 46 · see citing works
Ventral pallidal encoding of reward-seeking behavior depends on the underlying associative structure
Richard, J. M., Stout, N., Acs, D., & Janak, P. H. (2018) · eLife · doi:10.7554/elife.33107 · Cited by 44 · see citing works
Wang, D. V., Viereckel, T., Zell, V., Konradsson‐Geuken, Å., Broker, C. J., Talishinsky, A., Yoo, J. H., Galinato, M. H., Arvidsson, E., Kesner, A. J., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.02.062 · Cited by 40 · see citing works
Accumbal Dopamine Release Tracks the Expectation of Dopamine Neuron-Mediated Reinforcement
Covey, D. P., & Cheer, J. F. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.03.055 · Cited by 34 · see citing works
Mineur, Y. S., Brunzell, D. H., Grady, S. R., Lindstrom, J. M., McIntosh, J. M., Marks, M. J., King, S. L., & Picciotto, M. R. (2009) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2008.00468.x · Cited by 33 · see citing works
Unit Activity: Motivation-Dependent Responses from Midbrain Neurons
Phillips, M. I., & Olds, J. (1969) · Science · doi:10.1126/science.165.3899.1269 · Cited by 33 · see citing works
Synchronicity: The Role of Midbrain Dopamine in Whole-Brain Coordination
Beeler, J. A., & Dreyer, J. K. (2019) · eNeuro · doi:10.1523/eneuro.0345-18.2019 · Cited by 31 · see citing works
Hutchison, M. A., Gu, X., Adrover, M. F., LEE, M. R., Hnasko, T. S., Alvarez, V. A., & Lü, W. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.7 · Cited by 29 · see citing works
Farries, M. A., & Wilson, C. J. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00054.2012 · Cited by 27 · see citing works
Momiyama, T., & Nishijo, T. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00042 · Cited by 23 · see citing works
Wood, J. T., Simon, N. W., Koerner, F. S., Kass, R. E., & Moghaddam, B. (2017) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2017.00140 · Cited by 17 · see citing works
Decreases in Cued Reward Seeking After Reward-Paired Inhibition of Mesolimbic Dopamine
Fischbach-Weiss, S., & Janak, P. H. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.04.035 · Cited by 17 · see citing works
Evolution of Motor Systems: Corticospinal, Reticulospinal, Rubrospinal and Vestibulospinal Systems
ten Donkelaar, H. J. (2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_3131 · Cited by 12 · see citing works
A single spectrum of neuronal identities across thalamusPreprint
Phillips, J. W., Schulmann, A., Hara, E., Liu, C., Wang, L., Shields, B. C., Korff, W. L., Lemire, A. L., Dudman, J. T., Nelson, S. B., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/241315 · Cited by 11 · see citing works
Self-citationDopamine: Context and counterfactuals
Platt, M. L., & Pearson, J. M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1522315113 · Cited by 7 · see citing works
Context-dependent multiplexing by individual VTA dopamine neuronsPreprint
Kremer, Y., Flakowski, J., Rohner, C., & Lüscher, C. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/408062 · Cited by 5 · see citing works
VTA Dopamine Neurons Multiplex External with Internal Representations of Goal-Directed ActionPreprint
Kremer, Y., Flakowski, J., Rohner, C., & Lüscher, C. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3249465 · Cited by 4 · see citing works
Hughes, R. N., Watson, G. D. R., Petter, E. A., Kim, N., Bakhurin, K. I., & Yin, H. H. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/678391 · Cited by 2 · see citing works
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Spine dynamics in the brain, mental disorders and artificial neural networks
Kasai, H., Ziv, N. E., Okazaki, H., Yagishita, S., & Toyoizumi, T. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00467-3 · Cited by 180 · see citing works
Unique functional responses differentially map onto genetic subtypes of dopamine neurons
Azcorra, M., Gaertner, Z. A., Davidson, C., He, Q., Kim, H., Nagappan, S., Hayes, C. K., Ramakrishnan, C., Fenno, L. E., Kim, Y. S., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01401-9 · Cited by 170 · see citing works
Dopamine, Updated: Reward Prediction Error and Beyond
Lerner, T. N., Holloway, A. L., & Seiler, J. L. (2020) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.10.012 · Cited by 178 · see citing works
Modulating the Neuromodulators: Dopamine, Serotonin, and the Endocannabinoid System
Peters, K. Z., Cheer, J. F., & Tonini, R. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.02.001 · Cited by 171 · see citing works
Intrinsic dopamine and acetylcholine dynamics in the striatum of mice
Krok, A. C., Maltese, M., Mistry, P. N., Miao, X., Li, Y., & Tritsch, N. X. (2023) · Nature · doi:10.1038/s41586-023-05995-9 · Cited by 144 · see citing works
Mesocorticolimbic Dopamine Pathways Across Adolescence: Diversity in Development
Reynolds, L. M., & Flores, C. (2021) · Frontiers in Neural Circuits · doi:10.3389/fncir.2021.735625 · Cited by 137 · see citing works
Mesolimbic dopamine adapts the rate of learning from action
Coddington, L. T., Lindo, S. E., & Dudman, J. T. (2023) · Nature · doi:10.1038/s41586-022-05614-z · Cited by 118 · see citing works
Self-citationThe dopamine transporter gene SLC6A3: multidisease risks
Reith, M. E. A., Kortagere, S., Wiers, C. E., Sun, H., Kurian, M. A., Galli, A., Volkow, N. D., & Lin, Z. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01341-5 · Cited by 114 · see citing works
Heterogeneity in striatal dopamine circuits: Form and function in dynamic reward seeking
Collins, A. L., & Saunders, B. T. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24587 · Cited by 87 · see citing works
Basal Ganglia Circuits for Action Specification
Park, J., Coddington, L. T., & Dudman, J. T. (2020) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070918-050452 · Cited by 86 · see citing works
Self-citationDopaminergic action prediction errors serve as a value-free teaching signal
Greenstreet, F., Vergara, H. M., Johansson, Y., Pati, S., Schwarz, L., Lenzi, S. C., Geerts, J. P., Wisdom, M., Gubanova, A., Rollik, L. B., et al. (2025) · Nature · doi:10.1038/s41586-025-09008-9 · Cited by 87 · see citing works
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways
Zolin, A., Cohn, R., Pang, R., Siliciano, A. F., Fairhall, A. L., & Ruta, V. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00929-y · Cited by 81 · see citing works
A mosaic of cost–benefit control over cortico-striatal circuitry
Westbrook, A., Frank, M. J., & Cools, R. (2021) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2021.04.007 · Cited by 86 · see citing works
Mesoaccumbal Dopamine Heterogeneity: What Do Dopamine Firing and Release Have to Do with It?
de Jong, J. W., Fraser, K. M., & Lammel, S. (2022) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-110920-011929 · Cited by 81 · see citing works
Interpreting the role of the striatum during multiple phases of motor learning
Cataldi, S., Stanley, A. T., Miniaci, M. C., & Sulzer, D. (2021) · FEBS Journal · doi:10.1111/febs.15908 · Cited by 77 · see citing works
Hamilos, A. E., Spedicato, G., Hong, Y., Sun, F., Li, Y., & Assad, J. A. (2021) · eLife · doi:10.7554/elife.62583 · Cited by 79 · see citing works
Cortical State Fluctuations during Sensory Decision Making
Jacobs, E. A. K., Steinmetz, N. A., Peters, A. J., Carandini, M., & Harris, K. D. (2020) · Current Biology · doi:10.1016/j.cub.2020.09.067 · Cited by 69 · see citing works
Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety
Zhu, Z., Gong, R., Rodriguez, V., Quach, K. T., Chen, X., & Sternson, S. M. (2025) · Science · doi:10.1126/science.adt0773 · Cited by 82 · see citing works
Distributional Reinforcement Learning in the Brain
Lowet, A. S., Qiao, Z., Matias, S., Drugowitsch, J., & Uchida, N. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.09.004 · Cited by 69 · see citing works
Stress relief as a natural resilience mechanism against depression-like behaviors
Dong, Y., Li, Y., Xiang, X., Xiao, Z.-C., Hu, J., Li, Y., Li, H., & Hu, H. (2023) · Neuron · doi:10.1016/j.neuron.2023.09.004 · Cited by 69 · see citing works
Dopamine modulation of sensory processing and adaptive behavior in flies
Siju, K. P., Backer, J. D., & Kadow, I. C. G. (2021) · Cell and Tissue Research · doi:10.1007/s00441-020-03371-x · Cited by 66 · see citing works
Alm, P. A. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.661880 · Cited by 59 · see citing works
Muscarinic Receptor Activators as Novel Treatments for Schizophrenia
Paul, S. M., Yohn, S. E., Brannan, S. K., Neugebauer, N. M., & Breier, A. F. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.03.014 · Cited by 61 · see citing works
Dopamine dynamics are dispensable for movement but promote reward responses
Cai, X., Liu, C., Tsutsui‐Kimura, I., Lee, J.-H., Guo, C., Banerjee, A., Lee, J., Amo, R., Xie, Y., Patriarchi, T., et al. (2024) · Nature · doi:10.1038/s41586-024-08038-z · Cited by 63 · see citing works
State and rate-of-change encoding in parallel mesoaccumbal dopamine pathways
de Jong, J. W., Liang, Y., Verharen, J. P. H., Fraser, K. M., & Lammel, S. (2024) · Nature Neuroscience · doi:10.1038/s41593-023-01547-6 · Cited by 50 · see citing works
A neural circuit architecture for rapid learning in goal-directed navigation
Dan, C., Hulse, B. K., Kappagantula, R., Jayaraman, V., & Hermundstad, A. M. (2024) · Neuron · doi:10.1016/j.neuron.2024.04.036 · Cited by 51 · see citing works
Dopamine Axons in Dorsal Striatum Encode Contralateral Visual Stimuli and Choices
Moss, M. M., Zatka-Haas, P., Harris, K. D., Carandini, M., & Lak, A. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0490-21.2021 · Cited by 47 · see citing works
Thirst recruits phasic dopamine signaling through subfornical organ neurons
Hsu, T. M., Bazzino, P., Hurh, S. J., Konanur, V., Roitman, J. D., & Roitman, M. F. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2009233117 · Cited by 50 · see citing works
Aimon, S., Cheng, K. Y., Gjorgjieva, J., & Kadow, I. C. G. (2023) · eLife · doi:10.7554/elife.85202 · Cited by 49 · see citing works
Nigrostriatal dopamine pathway regulates auditory discrimination behavior
Chen, A. P. F., Malgady, J. M., Chen, L., Shi, K. W., Cheng, E., Plotkin, J. L., Ge, S., & Xiong, Q. (2022) · Nature Communications · doi:10.1038/s41467-022-33747-2 · Cited by 46 · see citing works
Park, A. T., Tooley, U. A., Leonard, J., Boroshok, A. L., McDermott, C. L., Tisdall, M. D., & Mackey, A. P. (2020) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2020.100909 · Cited by 46 · see citing works
Zhai, S., Cui, Q., Simmons, D. V., & Surmeier, D. J. (2023) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2023.102798 · Cited by 44 · see citing works
Renteria, R., Cazares, C., & Gremel, C. M. (2020) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14302 · Cited by 41 · see citing works
New roles for dopamine in motor skill acquisition: lessons from primates, rodents, and songbirds
Wood, A. N. (2021) · Journal of Neurophysiology · doi:10.1152/jn.00648.2020 · Cited by 39 · see citing works
Reinforcement learning links spontaneous cortical dopamine impulses to reward
Foo, C., Lozada, A. F., Aljadeff, J., Li, Y., Wang, J. W., Slesinger, P. A., & Kleinfeld, D. (2021) · Current Biology · doi:10.1016/j.cub.2021.06.069 · Cited by 36 · see citing works
Salvatore, M. F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021131 · Cited by 36 · see citing works
Nigrostriatal dopamine modulates the striatal-amygdala pathway in auditory fear conditioning
Chen, A. P. F., Chen, L., Shi, K. W., Cheng, E., Ge, S., & Xiong, Q. (2023) · Nature Communications · doi:10.1038/s41467-023-43066-9 · Cited by 32 · see citing works
Goedhoop, J. N., van den Boom, B. J. G., Robke, R., Veen, F., Fellinger, L., van Elzelingen, W., Arbab, T., & Willuhn, I. (2022) · eLife · doi:10.7554/elife.82711 · Cited by 29 · see citing works
Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens
Burke, D. A., & Alvarez, V. A. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110795 · Cited by 31 · see citing works
The Concept of Motor Reserve in Parkinson's Disease: New Wine in Old Bottles?
Hoenig, M. C., Dzialas, V., Drzezga, A. E., & van Eimeren, T. (2022) · Movement Disorders · doi:10.1002/mds.29266 · Cited by 31 · see citing works
John, Y. J., Caldwell, L., McCoy, D. E., & Braganza, O. (2023) · Behavioral and Brain Sciences · doi:10.1017/s0140525x23002753 · Cited by 32 · see citing works
Nigrostriatal dopamine signals sequence-specific action-outcome prediction errors
Hollon, N. G., Williams, E., Howard, C. D., Li, H., Traut, T. I., & Jin, X. (2021) · Current Biology · doi:10.1016/j.cub.2021.09.040 · Cited by 28 · see citing works
Köhler, R. M., Binns, T. S., Merk, T., Zhu, G., Yin, Z., Zhao, B., Chikermane, M., Vanhoecke, J., Busch, J. L., Habets, J., et al. (2024) · Brain · doi:10.1093/brain/awae219 · Cited by 28 · see citing works
Dissociable contributions of phasic dopamine activity to reward and prediction
Pan, W. X., Coddington, L. T., & Dudman, J. T. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109684 · Cited by 27 · see citing works
Self-citationDopamine neurons drive spatiotemporally heterogeneous striatal dopamine signals during learning
Engel, L., Wolff, A. R., Blake, M. L., Collins, V. L., Sinha, S., & Saunders, B. T. (2024) · Current Biology · doi:10.1016/j.cub.2024.05.069 · Cited by 27 · see citing works
Striatal BOLD and midfrontal theta power express motivation for action
Algermissen, J., Swart, J. C., Scheeringa, R., Cools, R., & den Ouden, H. E. M. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab391 · Cited by 27 · see citing works
Xiao, Y., Yang, J., Ji, W., He, Q., Mao, L., & Shu, Y. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108399 · Cited by 26 · see citing works
Reynolds, L. M., Faure, P., & Barik, J. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03110-0 · Cited by 26 · see citing works
Distributional coding of associative learning in discrete populations of midbrain dopamine neurons
Avvisati, R., Kaufmann, A.-K., Young, C. J., Portlock, G. E., Cancemi, S., Costa, R. P., Magill, P. J., & Dodson, P. D. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114080 · Cited by 29 · see citing works
Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning
Lopez, G. C., Camp, L. D. V., Kovaleski, R. F., Schaid, M. D., Moreno-Ramos, O. A., Rajeshwar, A. B., Cox, J., & Lerner, T. N. (2025) · Current Biology · doi:10.1016/j.cub.2025.04.006 · Cited by 22 · see citing works
Putaminal dopamine modulates movement motivation in Parkinson’s disease
Banwinkler, M., Dzialas, V., Rigoux, L., Asendorf, A. L., Theis, H., Giehl, K., Tittgemeyer, M., Hoenig, M. C., & van Eimeren, T. (2024) · Brain · doi:10.1093/brain/awae214 · Cited by 21 · see citing works
A neural circuit architecture for rapid behavioral flexibility in goal-directed navigation
Dan, C., Hulse, B. K., Kappagantula, R., Jayaraman, V., & Hermundstad, A. M. (2021) · doi:10.1101/2021.08.18.456004 · Cited by 51 · see citing works
Dopamine mediates the bidirectional update of interval timing.
Jakob, A. M. V., Mikhael, J. G., Hamilos, A. E., Assad, J. A., & Gershman, S. J. (2022) · Behavioral Neuroscience · doi:10.1037/bne0000529 · Cited by 20 · see citing works
Cavallo, A., & Neumann, W. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16222 · Cited by 19 · see citing works
Chang, S., Fermani, F., Lao, C. L., Huang, L., Jakovcevski, M., Giaimo, R. D., Gagliardi, M., Menegaz, D., Hennrich, A. A., Ziller, M. J., et al. (2022) · Science Advances · doi:10.1126/sciadv.abo1023 · Cited by 18 · see citing works
Striatal Dopamine Contributions to Skilled Motor Learning
Phillips, C. D., Hodge, A. T., Myers, C., Leventhal, D., & Burgess, C. R. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.0240-24.2024 · Cited by 17 · see citing works
Dong, X. Z., Sun, Z., Han, L., Yu, L., Li, B. L., Li, N. B., & Luo, H. Q. (2022) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2022.132668 · Cited by 15 · see citing works
Sensory Cues Potentiate VTA Dopamine Mediated Reinforcement
Wolff, A. R., & Saunders, B. T. (2024) · eNeuro · doi:10.1523/eneuro.0421-23.2024 · Cited by 17 · see citing works
Task goals shape the relationship between decision and movement speed
Fievez, F., Cos, I., Carsten, T., Derosière, G., Zénon, A., & Duqué, J. (2024) · Journal of Neurophysiology · doi:10.1152/jn.00126.2024 · Cited by 13 · see citing works
Song, M. R., & Lee, S. W. (2020) · Neural Networks · doi:10.1016/j.neunet.2020.03.005 · Cited by 13 · see citing works
Motor constellation theory: A model of infants’ phonological development
Ekström, A. G. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.996894 · Cited by 13 · see citing works
Rethinking the network determinants of motor disability in Parkinson’s disease
Surmeier, D. J., Zhai, S., Cui, Q., & Simmons, D. V. (2023) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2023.1186484 · Cited by 16 · see citing works
Cataldi, S., Lacefield, C., Shashaank, N., Kumar, G., Boumhaouad, S., & Sulzer, D. L. (2022) · eNeuro · doi:10.1523/eneuro.0169-22.2022 · Cited by 13 · see citing works
Cortical beta oscillations map to shared brain networks modulated by dopaminePreprint
Chikermane, M., Weerdmeester, L., Rajamani, N., Köhler, R. M., Merk, T., Vanhoecke, J., Horn, A., & Neumann, W. (2024) · eLife · doi:10.7554/elife.97184.3 · Cited by 23 · see citing works
Liakoni, V., Lehmann, M. P., Modirshanechi, A., Brea, J., Lutti, A., Gerstner, W., & Preuschoff, K. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118780 · Cited by 14 · see citing works
Preparation of Bimetallic Au-Pd/MWCNTs Electrode for Detection of Dopamine
Zhu, Z., Luk, H., Liu, Y.-S., Wu, R., Chung, M.-H., & Chang, X. (2022) · Minerals · doi:10.3390/min12091145 · Cited by 13 · see citing works
Overexpression of miR‑133b protects against isoflurane‑induced learning and memory impairment
Zhang, Y., Liu, J., Xie, C., & Wu, P. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.10641 · Cited by 12 · see citing works
Integrating across behaviors and timescales to understand the neural control of movement
Gmaz, J. M., Keller, J. A., Dudman, J. T., & Gallego, J. Á. (2024) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2024.102843 · Cited by 12 · see citing works
Self-citationFitzgerald, N. D., & Day, J. J. (2024) · Addiction Neuroscience · doi:10.1016/j.addicn.2024.100191 · Cited by 14 · see citing works
Dynamic dopaminergic activity controls the timing of self-timed movement.
Hamilos, A. E. (2021) · Digital Access to Scholarship at Harvard (DASH) (Harvard University) · Cited by 12 · see citing works
Intrinsic reward-like dopamine and acetylcholine dynamics in striatumPreprint
Krok, A. C., Mistry, P. N., Li, Y., & Tritsch, N. X. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.09.507300 · Cited by 12 · see citing works
Guida, P., Foffani, G., & Obeso, I. (2023) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01954 · Cited by 11 · see citing works
A permissive role for dopamine in the production of vigorous movementsPreprint
Liu, H., Melani, R., Sankaramanchi, A., Zeng, R., Maltese, M., Martin, J. R., & Tritsch, N. X. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.03.514328 · Cited by 10 · see citing works
From avoidance to new action: the multifaceted role of the striatal indirect pathway
Lee, J., & Sabatini, B. L. (2025) · Nature reviews. Neuroscience · doi:10.1038/s41583-025-00925-2 · Cited by 10 · see citing works
Cavallo, A., Köhler, R. M., Busch, J. L., Habets, J., Merk, T., Zvarova, P., Vanhoecke, J., Binns, T. S., Al‐Fatly, B., Marcelino, A. L. D. A., et al. (2025) · Science Advances · doi:10.1126/sciadv.adx6849 · Cited by 11 · see citing works
Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior
Herz, D. M., Bange, M., González‐Escamilla, G., Auer, M., Muthuraman, M., Glaser, M. B., Bogacz, R., Pogosyan, A. H., Tan, H., Groppa, S., et al. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3002140 · Cited by 11 · see citing works
Mantas, I., Contestabile, A., Skara, V., Loiseau, C., Santos, I., Cramb, K. M. L., Filograna, R., Wade‐Martins, R., Magill, P. J., & Meletis, K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.22.629963 · Cited by 10 · see citing works
Quantifying Dopaminergic Innervation in Rodents Using Unbiased Stereology
Reynolds, L. M., Pantoja-Urbán, A. H., MacGowan, D., Manitt, C., Nouel, D., & Flores, C. (2022) · Neuromethods · doi:10.1007/978-1-0716-2799-0_2 · Cited by 8 · see citing works
Kaduk, K., Henry, T., Guitton, J., Meunier, M., Thura, D., & Hadj‐Bouziane, F. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109736 · Cited by 8 · see citing works
Dopamine builds and reveals reward-associated latent behavioral attractors
Naudé, J., Sarazin, M., Mondoloni, S., Hannesse, B., Vicq, É., Amegandjin, F., Mourot, A., Fauré, P., & Delord, B. (2024) · Nature Communications · doi:10.1038/s41467-024-53976-x · Cited by 8 · see citing works
Representation learning with reward prediction errors
Alexander, W. H., & Gershman, S. J. (2022) · Neurons Behavior Data analysis and Theory · doi:10.51628/001c.37270 · Cited by 7 · see citing works
Striatal Dopamine Actions and Movement: Inferences from Parkinson Disease
Albin, R. L., Brissenden, J. A., Lee, T. G., & Leventhal, D. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0022-25.2025 · Cited by 7 · see citing works
Kalhan, S., Garrido, M. I., Hester, R., & Redish, A. D. (2023) · Neural Networks · doi:10.1016/j.neunet.2023.09.032 · Cited by 7 · see citing works
Getachew, B., Hauser, S. R., Bennani, S., Kouhen, N. E., Sari, Y., & Tizabi, Y. (2024) · Advances in Drug and Alcohol Research · doi:10.3389/adar.2024.11881 · Cited by 7 · see citing works
The learning primacy hypothesis of dopamine: reconsidering dopamine’s dual functions
Long, C., & Masmanidis, S. C. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1538500 · Cited by 6 · see citing works
Replay of procedural experience is independent of the hippocampusPreprint
Thompson, E. J., Rollik, L. B., Waked, B., Mills, G., Kaur, J., Geva, B., Carrasco-Davis, R., George, T. M., Dominé, C., Dorrell, W., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.05.597547 · Cited by 6 · see citing works
Neural correlates of vocal initiation in the VTA/SNc of juvenile male zebra finches
Yanagihara, S., Ikebuchi, M., Mori, C., Tachibana, R. O., & Okanoya, K. (2021) · Scientific Reports · doi:10.1038/s41598-021-01955-3 · Cited by 5 · see citing works
Avvisati, R., Kaufmann, A.-K., Young, C. J., Portlock, G. E., Cancemi, S., Costa, R. P., Magill, P. J., & Dodson, P. D. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.18.500429 · Cited by 5 · see citing works
Cortical beta oscillations map to shared brain networks modulated by dopaminePreprint
Chikermane, M., Weerdmeester, L., Rajamani, N., Köhler, R. M., Merk, T., Vanhoecke, J., Horn, A., & Neumann, W. (2024) · eLife · doi:10.7554/elife.97184.2 · Cited by 5 · see citing works
Sulaman, B. A., Chen, E., Crane, A. M., Lee, S.-J., Rothschild, G., & Eban-Rothschild, A. (2025) · Science Advances · doi:10.1126/sciadv.adw7427 · Cited by 4 · see citing works
Free will: An Example of the Dopaminergic System
Ivlieva, N. Y. (2024) · Integrative Psychological and Behavioral Science · doi:10.1007/s12124-024-09828-w · Cited by 4 · see citing works
Xia, L., Stoika, R. S., Li, Y., Zheng, Y., Liu, Y., Li, D., Liu, K., Zhang, X., Shang, X., & Jin, M. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.179212 · Cited by 4 · see citing works
Striatum-wide dopamine encodes trajectory errors separated from value
Brown, E. H., Zi, Y., Vu, M.-A. T., Bouabid, S., Lindsey, J. W., Godfrey-Nwachukwu, C., Attarwala, A., Litwin-Kumar, A., DePasquale, B., & Howe, M. W. (2026) · Nature · doi:10.1038/s41586-025-10083-1 · Cited by 4 · see citing works
Brain neuronal CG9593/ANGPTL4 activation mediates paternally acquired motor disorders
Zhang, J., Wei, T., Xiong, Y.-W., Guan, S.-Z., Zhou, H., Fan, L.-L., Nie, Y., Yuan, Z., Li, H., Wang, K.-W., et al. (2026) · Science Advances · doi:10.1126/sciadv.aea8321 · Cited by 3 · see citing works
TetrODrive: an open-source microdrive for combined electrophysiology and optophysiology
Brosch, M., Vlasenko, A., Ohl, F. W., & Lippert, M. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/abf608 · Cited by 3 · see citing works
McGregor, M. M., & Nelson, A. (2020) · Neuron · doi:10.1016/j.neuron.2020.04.005 · Cited by 3 · see citing works
Cataldi, S., Lacefield, C., Shashaank, N., Kumar, G., & Sulzer, D. L. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.07.447452 · Cited by 3 · see citing works
Monoaminergic neurons share transcriptional identity across Bilaterian animalsPreprint
Goulty, M., Lewis, C., Nicolini, F., Khalid, R., Syed, H., Oliveri, P., Thomas, M. G., Rosato, E., & Feuda, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.10.679534 · Cited by 3 · see citing works
Halfhide, C., Cammarano, T. L., Anderson, K. A., Galik, S. M., Rossignol, J., Dunbar, G. L., & Sandstrom, M. I. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.115121 · Cited by 2 · see citing works
Subtype-specific roles of nigrostriatal dopaminergic neurons in motor and associative learning
Habib, A., Riccobono, G., Tian, L., Basu, D., Sun, L., Chang, L., Smith, V. M. M., Wang, L., Le, W., & Cai, H. (2025) · Ageing and Neurodegenerative Diseases · doi:10.20517/and.2025.26 · Cited by 2 · see citing works
- Authors
- Coddington, L. T., & Dudman, J. T.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Coddington, Luke T.
- Dudman, Joshua T.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2019-10
- Volume
- 104
- Issue
- 1
- Pages
- 63-77
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2979619911
- Cited by
- 150
- References
- 186
- Citations by year
- 2026: 18 · 2025: 24 · 2024: 27 · 2023: 19 · 2022: 24 · 2021: 24 · 2020: 14
- FWCI
- 2.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Howard Hughes Medical Institute
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- dopamine, midbrain dopaminergic neurons, movement initiation, reward prediction, credit assignment
- MeSH terms
- Animals, Humans, Learning, Mesencephalon, Movement, Reward, Dopaminergic Neurons
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