Reduced Adult Hippocampal Neurogenesis and Working Memory Deficits in the Dgcr8-Deficient Mouse Model of 22q11.2 Deletion-Associated Schizophrenia Can Be Rescued by IGF2

The Mouse Brain in Stereotaxic Coordinates

Paxinos, G. (2001) · Cited by 12,859 · see citing works

Mammalian neural stem cells.

Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 3,949 · see citing works

Mechanisms and Functional Implications of Adult Neurogenesis

Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007 · see citing works

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Liu, J.-P., Baker, J. C., Perkins, A. S., Robertson, E. J., & Efstratiadis, A. (1993) · Cell · doi:10.1016/s0092-8674(05)80084-4 · Cited by 2,854 · see citing works

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

Ming, G.-L., & Song, H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.001 · Cited by 2,651 · see citing works

Role of insulin-like growth factors in embryonic and postnatal growth

Baker, J., Liu, J.-P., Robertson, E. J., & Efstratiadis, A. (1993) · Cell · doi:10.1016/s0092-8674(05)80085-6 · Cited by 2,463 · see citing works

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

Deng, W., Aimone, J. B., & Gage, F. H. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2822 · Cited by 2,120 · see citing works

MicroRNA biogenesis: coordinated cropping and dicing

Kim, V. N. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1644 · Cited by 2,019 · see citing works

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

Sahay, A., Scobie, K. N., Hill, A. S., O'Carroll, C. M., Kheirbek, M. A., Burghardt, N. S., Fenton, A. A., Dranovsky, A., & Hen, R. (2011) · Nature · doi:10.1038/nature09817 · Cited by 1,567 · see citing works

High rates of schizophrenia in adults with velo-cardio-facial syndrome

Murphy, K. C., Jones, L. A., & Owen, M. J. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.10.940 · Cited by 1,024 · see citing works

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

Mao, Y., Ge, X., Frank, C. L., Madison, J. M., Koehler, A. N., Doud, M. K., Tassa, C., Berry-Scott, E., Soda, T., Singh, K. K., et al. (2009) · Cell · doi:10.1016/j.cell.2008.12.044 · Cited by 768 · see citing works

Untitled work

(2003) · doi:10.1542/peds.112.1.101 · Cited by 695 · see citing works

The cerebrospinal fluid provides a proliferative niche for neural progenitor cells

Lehtinen, M. K., Zappaterra, M. W., Chen, X., Yang, Y. J., Hill, A. D., Lun, M., Maynard, T., Gonzalez, D., Kim, S., Ye, P., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.023 · Cited by 648 · see citing works

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

Stark, K. L., Xu, B., Bagchi, A., Lai, W.-S., Liu, H., Hsu, R., Wan, X., Pavlidis, P., Mills, A. A., Karayiorgou, M., et al. (2008) · Nature Genetics · doi:10.1038/ng.138 · Cited by 648 · see citing works

Neural stem cell proliferation is decreased in schizophrenia, but not in depression

Reif, A., Fritzen, S., Finger, M., Strobel, A., Lauer, M., Schmitt, A., & Lesch, K.-P. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001791 · Cited by 630 · see citing works

Short‐term and long‐term survival of new neurons in the rat dentate gyrus

Dayer, A. G., Ford, A. A., Cleaver, K. M., Yassaee, M., & Cameron, H. A. (2003) · Journal of Comparative Neurology · doi:10.1002/cne.10675 · Cited by 628 · see citing works

Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.Preprint

Lau, M. M., Stewart, C. E., Liu, Z., Bhatt, H., Rotwein, P. S., & Stewart, C. L. (1994) · Genes & Development · doi:10.1101/gad.8.24.2953 · Cited by 602 · see citing works

A new syndrome involving cleft palate, cardiac anomalies, typical facies, and learning disabilities: velo-cardio-facial syndrome.

Shprintzen, R. J., Goldberg, R. B., Lewin, M. L., Sidoti, E. J., Berkman, M. D., Argamaso, R. V., & Young, D. (1978) · PubMed · Cited by 593 · see citing works

BACE1 Deficiency Rescues Memory Deficits and Cholinergic Dysfunction in a Mouse Model of Alzheimer's Disease

Ohno, M., Sametsky, E. A., Younkin, L. H., Oakley, H., Younkin, S. G., Citron, M., Vassar, R., & Disterhoft, J. F. (2004) · Neuron · doi:10.1016/s0896-6273(03)00810-9 · Cited by 549 · see citing works

Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus

Mira, H., Andreu, Z., Suh, H., Lie, D. C., Jessberger, S., Consiglio, A., San Emeterio, J., Hortigüela, R., Marqués-Torrejón, M. Á., Nakashima, K., et al. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.04.016 · Cited by 480 · see citing works

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

Karayiorgou, M., Simon, T. J., & Gogos, J. A. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2841 · Cited by 474 · see citing works

Psychotic Illness in Patients Diagnosed with Velo-Cardio-Facial Syndrome and Their Relatives

Pulver, A. E., Nestadt, G., Goldberg, R. B., Shprintzen, R. J., Lamacz, M., Wolyniec, P. S., Morrow, B. E., Karayiorgou, M., Antonarakis, S. E., Housman, D. E., et al. (1994) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199408000-00010 · Cited by 421 · see citing works

A critical role for IGF-II in memory consolidation and enhancement

Chen, D. Y., Stern, S. A., García‐Osta, A., Saunier-Rebori, B., Pollonini, G., Bambah-Mukku, D., Blitzer, R. D., & Alberini, C. M. (2011) · Nature · doi:10.1038/nature09667 · Cited by 421 · see citing works

Early age-related changes in adult hippocampal neurogenesis in C57 mice

Abdallah, N. M. ‐. B., Slomianka, L., Vyssotski, A. L., & Lipp, H. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.03.002 · Cited by 368 · see citing works

A new concept of the cellular basis of immunity

Cooper, M. D., Peterson, R. D. A., & Good, R. A. (1965) · The Journal of Pediatrics · doi:10.1016/s0022-3476(65)81796-6 · Cited by 364 · see citing works

BrdU assay for neurogenesis in rodents

Wojtowicz, J. M., & Kee, N. (2006) · Nature Protocols · doi:10.1038/nprot.2006.224 · Cited by 349 · see citing works

Genetics of mouse growth

Efstratiadis, A. (1998) · The International Journal of Developmental Biology · doi:10.1387/ijdb.9853827 · Cited by 349 · see citing works

The Adult Mouse Hippocampal Progenitor Is Neurogenic But Not a Stem Cell

Bull, N. D., & Bartlett, P. F. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3249-05.2005 · Cited by 242 · see citing works

Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning

Guo, W., Allan, A. M., Zong, R.-T., Zhang, L., Johnson, E. B., Schaller, E., Murthy, A. C., Goggin, S. L., Eisch, A. J., Oostra, B. A., et al. (2011) · Nature Medicine · doi:10.1038/nm.2336 · Cited by 221 · see citing works

Quantitative autoradiographic localization of [125I]insulin‐like growth factor I, [125I]insulin‐like growth factor II, and [125I]insulin receptor binding sites in developing and adult rat brain

Kar, S., Chabot, J., & Quirion, R. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903330306 · Cited by 210 · see citing works

Molecular profiles of schizophrenia in the CNS at different stages of illness

Narayan, S., Tang, B., Head, S. R., Gilmartin, T. J., Sutcliffe, J. G., Dean, B., & Thomas, E. A. (2008) · Brain Research · doi:10.1016/j.brainres.2008.08.023 · Cited by 204 · see citing works

Gene Expression Profiling of Neural Stem Cells and Their Neuronal Progeny Reveals IGF2 as a Regulator of Adult Hippocampal Neurogenesis

Bracko, O., Singer, T., Aigner, S., Knobloch, M., Winner, B., Ray, J., Clemenson, G. D., Suh, H., Couillard‐Després, S., Aigner, L., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.4248-11.2012 · Cited by 201 · see citing works

Programmed Cell Death of Adult-Generated Hippocampal Neurons Is Mediated by the Proapoptotic Gene Bax

Sun, W., Winseck, A. K., Vinsant, S. L., Park, O., Kim, H., & Oppenheim, R. W. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1436-04.2004 · Cited by 197 · see citing works

Disease Biomarkers in Cerebrospinal Fluid of Patients with First-Onset Psychosis

Huang, J. T.-J., Leweke, F. M., Oxley, D., Wang, L., Harris, N., Koethe, D., Gerth, C. W., Nolden, B. M., Gross, S., Schreiber, D., et al. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030428 · Cited by 169 · see citing works

Pax6 is required for production and maintenance of progenitor cells in postnatal hippocampal neurogenesis

Maekawa, M., Takashima, N., Arai, Y., Nomura, T., Inokuchi, K., Yuasa, S., & Osumi, N. (2005) · Genes to Cells · doi:10.1111/j.1365-2443.2005.00893.x · Cited by 156 · see citing works

A hippocampal insulin‐growth factor 2 pathway regulates the extinction of fear memories

Agís‐Balboa, R. C., Arcos-Díaz, D. P., Wittnam, J. L., Govindarajan, N., Blom, K., Burkhardt, S., Haladyniak, U., Agbemenyah, H. Y., Zovoilis, A., Salinas-Riester, G., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.293 · Cited by 145 · see citing works

IGF-II Promotes Stemness of Neural Restricted Precursors

Ziegler, A. N., Schneider, J., Qin, M., Tyler, W. A., Pintar, J. E., Fraidenraich, D., Wood, T. L., & Levison, S. W. (2012) · Stem Cells · doi:10.1002/stem.1095 · Cited by 89 · see citing works

Type 1 insulin‐like growth factor receptor signaling is essential for the development of the hippocampal formation and dentate gyrus

Liu, W., Ye, P., OʼKusky, J. R., & D’Ercole, A. J. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22129 · Cited by 84 · see citing works

Hormones and schizophrenia

Kulkarni, J., Hayes, E., & Gavrilidis, E. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328350360e · Cited by 74 · see citing works

Expression of insulin‐like growth factor system genes during the early postnatal neurogenesis in the mouse hippocampus

Zhang, J., Moats‐Staats, B. M., Ye, P., & D’Ercole, A. J. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21289 · Cited by 52 · see citing works

Serotonin receptor 2C (HTR2C) and schizophrenia: Examination of possible medication and genetic influences on expression levels

Castensson, A., Åberg, K. A., McCarthy, S., Saetre, P., Andersson, B., & JAZIN, E. E. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30151 · Cited by 36 · see citing works

Reduction of Angiotensin-Converting Enzyme in Substantia Nigra in Early-Onset Schizophrenia

Arregui, A., Mackay, A. V. P., Iversen, L. L., et al. (1979) · New England Journal of Medicine · doi:10.1056/nejm197903013000921 · Cited by 34 · see citing works

Running wheel exercises accelerate neuronal turnover in mouse dentate gyrus

Kitamura, T., & Sugiyama, H. (2006) · Neuroscience Research · doi:10.1016/j.neures.2006.05.006 · Cited by 23 · see citing works

Gene expression elucidates functional impact of polygenic risk for schizophrenia

Fromer, M., Roussos, P., Sieberts, S. K., Johnson, J. S., Kavanagh, D. H., Perumal, T. M., Ruderfer, D. M., Oh, E. C., Topol, A., Shah, H. R., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4399 · Cited by 1,091 · see citing works

Emerging role of microRNAs in major depressive disorder: diagnosis and therapeutic implications

Dwivedi, Y. (2014) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2014.16.1/ydwivedi · Cited by 169 · see citing works

Hippocampal Neurogenesis and Ageing

Couillard‐Després, S. (2012) · Current topics in behavioral neurosciences · doi:10.1007/7854_2012_232 · Cited by 27 · see citing works

Neurogenesis within the adult hippocampus under physiological conditions and in depression.

Dokter, M., & Halbach, O. V. B. U. (2012) · Europe PMC (PubMed Central) · doi:10.3969/j.issn.1673-5374.2012.07.013 · Cited by 19 · see citing works

Review: adult neurogenesis contributes to hippocampal plasticity

Toda, T., & Gage, F. H. (2017) · Cell and Tissue Research · doi:10.1007/s00441-017-2735-4 · Cited by 262 · see citing works

Metabolic tuning of inhibition regulates hippocampal neurogenesis in the adult brain

Wang, X., Liu, H., Morstein, J., Novak, A. J. E., Trauner, D. H., Xiong, Q., Yu, Y., & Ge, S. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2006138117 · Cited by 23 · see citing works

Modeling the influence of heavy ion beams on neurogenesis and functioning of hippocampal neural networks

Kolesnikova, E. A., & Bugay, A. N. (2019) · EPJ Web of Conferences · doi:10.1051/epjconf/201920404007