Distinct transcriptomes define rostral and caudal serotonin neurons

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482 · see citing works

Cluster analysis and display of genome-wide expression patterns

Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 12,617 · see citing works

limma: Linear Models for Microarray Data

Smyth, G. K. (2005) · Statistics for Biology and Health · doi:10.1007/0-387-29362-0_23 · Cited by 5,796 · see citing works

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129 · see citing works

The spectrum of behaviors influenced by serotonin

Lucki, I. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00139-5 · Cited by 1,154 · see citing works

Common genetic variants on 5p14.1 associate with autism spectrum disorders

Wang, K., Zhang, H., Ma, D., Bucan, M., Glessner, J. T., Abrahams, B. S., Salyakina, D., Imielinski, M., Bradfield, J. P., Sleiman, P. M. A., et al. (2009) · Nature · doi:10.1038/nature07999 · Cited by 989 · see citing works

Application of a translational profiling approach for the comparative analysis of CNS cell types

Doyle, J. P., Dougherty, J. D., Heiman, M., Schmidt, E. F., Stevens, T. R., Ma, G., Bupp, S., Shrestha, P., Shah, R. D., Doughty, M. L., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.029 · Cited by 912 · see citing works

Modulating Hox gene functions during animal body patterning

Pearson, J. C., Lemons, D., & McGinnis, W. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1726 · Cited by 879 · see citing works

FGF and Shh Signals Control Dopaminergic and Serotonergic Cell Fate in the Anterior Neural Plate

Ye, W., Shimamura, K., Rubenstein, J. L. R., Hynes, M., & Rosenthal, A. (1998) · Cell · doi:10.1016/s0092-8674(00)81437-3 · Cited by 878 · see citing works

Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system

Hökfelt, T. G. M., Ljungdahl, Å., Steinbusch, H. W. M., Verhofstad, A. A. J., Nilsson, G., Brodin, E., Pernow, B., & Goldstein, M. (1978) · Neuroscience · doi:10.1016/0306-4522(78)90017-9 · Cited by 814 · see citing works

A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism

Arking, D. E., Cutler, D. J., Brune, C. W., Teslovich, T. M., West, K., Ikeda, M., Rea, A., Guy, M., Lin, S., Cook, E. H., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.09.015 · Cited by 590 · see citing works

Disruption of neurexin 1 associated with autism spectrum disorder

Kim, H.-G., Kishikawa, S., Higgins, A. W., Seong, I.-S., Donovan, D. J., Shen, Y., Lally, E., Weiss, L. A., Najm, J., Kutsche, K., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.09.011 · Cited by 578 · see citing works

Molecular taxonomy of major neuronal classes in the adult mouse forebrain

Sugino, K., Hempel, C. M., Miller, M. N., Hattox, A. M., Shapiro, P., Wu, C., Huang, Z. J., & Nelson, S. B. (2006) · Nature Neuroscience · doi:10.1038/nn1618 · Cited by 521 · see citing works

Serotonin and substance P coexist in neurons of the rat's central nervous system

Chan‐Palay, V., JONSSON, G., & Palay, S. L. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.3.1582 · Cited by 487 · see citing works

Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior.

Hendricks, T. J., Fyodorov, D., Wegman, L. J., Lelutiu, N. B., Pehek, E. A., Yamamoto, B., Silver, J., Weeber, E., Sweatt, J., & Deneris, E. S. (2003) · Neuron · doi:10.1016/s0896-6273(02)01167-4 · Cited by 486 · see citing works

A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity

Dasen, J. S., Tice, B. C., Brenner-Morton, S., & Jessell, T. M. (2005) · Cell · doi:10.1016/j.cell.2005.09.009 · Cited by 461 · see citing works

Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development

Joyner, A. L. (1996) · Trends in Genetics · doi:10.1016/0168-9525(96)81383-7 · Cited by 439 · see citing works

Characterization of Potocki-Lupski Syndrome (dup(17)(p11.2p11.2)) and Delineation of a Dosage-Sensitive Critical Interval That Can Convey an Autism Phenotype

Potocki, L., Bi, W., Treadwell‐Deering, D., Carvalho, C. M. B., Eifert, A., Friedman, E. M., Glaze, D. G., Krull, K. R., Lee, J. A., Lewis, R. A., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/512864 · Cited by 425 · see citing works

Genomic imprinting effects on brain development and function

Wilkinson, L. S., Davies, W., & Isles, A. R. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2235 · Cited by 373 · see citing works

Growth retardation and altered autonomic control in mice lacking brain serotonin

Alenina, N. V., Kikic, D., Todiraş, M., Mosienko, V., Qadri, F., Plehm, R., Boyé, P., Vilianovich, L., Sohr, R., Tenner, K., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810793106 · Cited by 349 · see citing works

Serotonin and brain development

Sodhi, M., & Sanders‐Bush, E. (2004) · International review of neurobiology · doi:10.1016/s0074-7742(04)59006-2 · Cited by 337 · see citing works

Neuronal Transcriptome of Aplysia: Neuronal Compartments and Circuitry

Moroz, L. L., Edwards, J. R., Puthanveettil, S. V., Kohn, A. B., Ha, T. J., Heyland, A., Knudsen, B., Sahni, A., Yu, F., Liu, L., et al. (2006) · Cell · doi:10.1016/j.cell.2006.09.052 · Cited by 323 · see citing works

Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum

Davis, C. A., Holmyard, D. P., Millen, K. J., & Joyner, A. L. (1991) · Development · doi:10.1242/dev.111.2.287 · Cited by 321 · see citing works

The MAGE proteins: Emerging roles in cell cycle progression, apoptosis, and neurogenetic disease

Barker, P. A., & Salehi, A. H. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10160 · Cited by 320 · see citing works

Mechanisms of imprinting of the Prader-Willi/Angelman region

Horsthemke, B., & Wagstaff, J. (2008) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32364 · Cited by 320 · see citing works

Defects in Breathing and Thermoregulation in Mice with Near-Complete Absence of Central Serotonin Neurons

Hodges, M. R., Tattersall, G. J., Harris, M. B., McEvoy, S. D., Richerson, D. N., Deneris, E. S., Johnson, R. L., Chen, Z., & Richerson, G. B. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4729-07.2008 · Cited by 320 · see citing works

The ETS Domain Factor Pet-1 Is an Early and Precise Marker of Central Serotonin Neurons and Interacts with a Conserved Element in Serotonergic Genes

Hendricks, T. J., Francis, N. J., Fyodorov, D. V., & Deneris, E. S. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-23-10348.1999 · Cited by 300 · see citing works

An anatomic gene expression atlas of the adult mouse brain

Ng, L., Bernard, A., Lau, C., Overly, C. C., Dong, H., Kuan, C. L., Pathak, D. S., Sunkin, S. M., Dang, C., Bohland, J. W., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2281 · Cited by 279 · see citing works

Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease

Holmes, A. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.03.006 · Cited by 264 · see citing works

[8] Bioconductor: An Open Source Framework for Bioinformatics and Computational Biology

Reimers, M., & Carey, V. J. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)11008-3 · Cited by 263 · see citing works

Coordinated Actions of the Forkhead Protein Foxp1 and Hox Proteins in the Columnar Organization of Spinal Motor Neurons

Rousso, D. L., Gaber, Z. B., Wellik, D. M., Morrisey, E. E., & Novitch, B. G. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.025 · Cited by 254 · see citing works

Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors.Preprint

Pattyn, A., Vallstedt, A., Dias, J. M., Samad, O. A., Krumlauf, R., Rijli, F., Brunet, J., & Ericson, J. (2003) · Genes & Development · doi:10.1101/gad.255803 · Cited by 247 · see citing works

Redefining the serotonergic system by genetic lineage

Jensen, P., Farago, A. F., Awatramani, R. B., Scott, M. M., Deneris, E. S., & Dymecki, S. M. (2008) · Nature Neuroscience · doi:10.1038/nn2050 · Cited by 244 · see citing works

Contributions of the Medullary Raphe and Ventromedial Reticular Region to Pain Modulation and Other Homeostatic Functions

Mason, P. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.737 · Cited by 240 · see citing works

A genetic approach to access serotonin neurons for in vivo and in vitro studies

Scott, M. M., Wylie, C. J., Lerch, J. K., Murphy, R., Lobur, K. J., Herlitze, S., Jiang, W., Conlon, R. A., Strowbridge, B. W., & Deneris, E. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504510102 · Cited by 233 · see citing works

Sleep and breathing in Prader‐Willi syndrome

Nixon, G. M., & Brouillette, R. T. (2002) · Pediatric Pulmonology · doi:10.1002/ppul.10152 · Cited by 210 · see citing works

Immunohistochemical evidence for the presence of γ-aminobutyric acid and serotonin in one nerve cell. A study on the raphe nuclei of the rat using antibodies to glutamate decarboxylase and serotonin

Belin, M., Nanopoulos, D., Didier‐Bazès, M., Aguera, M., Steinbusch, H. W. M., Verhofstad, A. A. J., Maître, M., & Pujol, J. F. (1983) · Brain Research · doi:10.1016/0006-8993(83)90994-0 · Cited by 206 · see citing works

Differential expression of 5HT‐1A, α1b adrenergic, CRF‐R1, and CRF‐R2 receptor mRNA in serotonergic, γ‐aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus

Day, H. E. W., Greenwood, B. N., Hammack, S. E., Watkins, L. R., Fleshner, M., Maier, S. F., & Campeau, S. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20138 · Cited by 201 · see citing works

Neurodevelopmental origins of depressive disorders

Ansorge, M. S., Hen, R., & Gingrich, J. A. (2006) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2006.11.006 · Cited by 189 · see citing works

Transcriptional regulation at a HTR1A polymorphism associated with mental illness

François, B. L., Czesak, M., Steubl, D., & Albert, P. R. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.06.046 · Cited by 185 · see citing works

Genetics of Affective and Anxiety Disorders

Leonardo, E. D., & Hen, R. (2005) · Annual Review of Psychology · doi:10.1146/annurev.psych.57.102904.190118 · Cited by 184 · see citing works

Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase

Prasad, H. C., Zhu, C.-B., McCauley, J. L., Samuvel, D. J., Ramamoorthy, S., Shelton, R. C., Hewlett, W. A., Sutcliffe, J. S., & Blakely, R. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501432102 · Cited by 180 · see citing works

Median and Dorsal Raphe Neurons Are Not Electrophysiologically Identical

Beck, S. G., Pan, Y., Akanwa, A. C., & Kirby, L. G. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00744.2003 · Cited by 166 · see citing works

Distinct Roles for Ceramide and Glucosylceramide at Different Stages of Neuronal Growth

Schwarz, A., & Futerman, A. H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-09-02929.1997 · Cited by 163 · see citing works

Serotonergic neuron diversity: Identification of raphe neurons with discharges time-locked to the hippocampal theta rhythm

Kocsis, B., Varga, V., Dahan, L., & Attila Gabor, S. I. K. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508360103 · Cited by 158 · see citing works

Sphingosine Facilitates SNARE Complex Assembly and Activates Synaptic Vesicle Exocytosis

Darios, F., Wasser, C. R., Shakirzyanova, A., Giniatullin, A., Goodman, K., Muñoz-Bravo, J. L., Raingo, J., Jorgačevski, J., Kreft, M., Zorec, R., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.04.024 · Cited by 157 · see citing works

Mice Lacking Central Serotonergic Neurons Show Enhanced Inflammatory Pain and an Impaired Analgesic Response to Antidepressant Drugs

Zhao, Z.-Q., Chiechio, S., Sun, Y.-G., Zhang, K., Zhao, C., Scott, M. M., Johnson, R. L., Deneris, E. S., Renner, K. J., Gereau, R. W., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1623-07.2007 · Cited by 146 · see citing works

Essential role for the Prader–Willi syndrome protein necdin in axonal outgrowth

Lee, S., Walker, C. L., Karten, B., Kuny, S., Tennese, A. A., O’Neill, M. A., & Wevrick, R. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi059 · Cited by 136 · see citing works

Hmx2 and Hmx3 Homeobox Genes Direct Development of the Murine Inner Ear and Hypothalamus and Can Be Functionally Replaced by Drosophila Hmx

Wang, W., Grimmer, J. F., Water, T. R. V. D., & Lufkin, T. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.06.016 · Cited by 131 · see citing works

Absence ofNdn, Encoding the Prader-Willi Syndrome-Deleted Genenecdin, Results in Congenital Deficiency of Central Respiratory Drive in Neonatal Mice

Ren, J. T., Lee, S., Pagliardini, S., Gérard, M., Stewart, C. L., Greer, J. J., & Wevrick, R. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01569.2003 · Cited by 126 · see citing works

Sphingolipid metabolites in neural signalling and function

Colombaioni, L., & Garcia‐Gil, M. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.07.014 · Cited by 119 · see citing works

Multiple messengers in descending serotonin neurons: localization and functional implications

Hökfelt, T. G. M., Arvidsson, U., Cullheim, S., Millhorn, D. E., Nicholas, A. P., Pieribone, V. A., Seroogy, K. B., & Ulfhake, B. (2000) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(99)00037-x · Cited by 113 · see citing works

Serotonergic transcriptional programming determines maternal behavior and offspring survival

Lerch, J. K., Frierson, D. M. W., Crawford, L. K., Beck, S. G., & Deneris, E. S. (2008) · Nature Neuroscience · doi:10.1038/nn.2176 · Cited by 107 · see citing works

Regionally reduced brain volume, altered serotonin neurochemistry, and abnormal behavior in mice null for the circadian rhythm output gene Magel2

Mercer, R. E., Kwolek, E., Bischof, J. M., van Eede, M., Henkelman, R. M., & Wevrick, R. (2009) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30934 · Cited by 103 · see citing works

Loss of Magel2, a Candidate Gene for Features of Prader-Willi Syndrome, Impairs Reproductive Function in Mice

Mercer, R. E., & Wevrick, R. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004291 · Cited by 102 · see citing works

The serotonergic phenotype is acquired by converging genetic mechanisms within the zebrafish central nervous system

Lillesaar, C., Tannhäuser, B., Stigloher, C., Kremmer, E., & Bally‐Cuif, L. (2007) · Developmental Dynamics · doi:10.1002/dvdy.21095 · Cited by 101 · see citing works

Antibody-based therapies for malaria

Pleass, R. J., & Holder, A. A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1267 · Cited by 99 · see citing works

Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges

Erickson, J. T., Shafer, G. O., Rossetti, M. D., Wilson, C. G., & Deneris, E. S. (2007) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2007.06.002 · Cited by 97 · see citing works

Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis

Jacob, J., Ferri, L., Milton, C. I., Prin, F., Pla, P., Lin, W., Gavalas, A., Ang, S., & Briscoe, J. (2007) · Nature Neuroscience · doi:10.1038/nn1985 · Cited by 90 · see citing works

Necdin Plays a Role in the Serotonergic Modulation of the Mouse Respiratory Network: Implication for Prader-Willi Syndrome

Zanella, S., Françoise Watrin, A., Mebarek, S., Marly, F., Roussel, M., Gire, C., Diene, G., Tauber, M., Muscatelli, F., & Hilaire, G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4334-07.2008 · Cited by 87 · see citing works

Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors

Simon, H. H., Thuret, S., & Alberi, L. A. (2004) · Cell and Tissue Research · doi:10.1007/s00441-004-0973-8 · Cited by 82 · see citing works

Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner

Simon, H. H., Scholz, C., & O’Leary, D. D. M. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.08.016 · Cited by 68 · see citing works

An Integrated Approach for the Analysis of Biological Pathways using Mixed Models

Wang, L., Zhang, B., Wolfinger, R. D., & Chen, X. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000115 · Cited by 62 · see citing works

Immunocytochemical evidence for the existence of substance P receptor (NK1) in serotonin neurons of rat and mouse dorsal raphe nucleus

Lacoste, B., Riad, M., & Descarries, L. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04833.x · Cited by 47 · see citing works

Sizn1 Is a Novel Protein That Functions as a Transcriptional Coactivator of Bone Morphogenic Protein Signaling

Cho, G., Lim, Y., Zand, D. J., & Golden, J. A. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01038-07 · Cited by 38 · see citing works

Evidence that SIZN1 is a candidate X‐linked mental retardation gene

Cho, G., Bhat, S. S., Gao, J., Collins, J. S., Rogers, R. C., Simensen, R. J., Schwartz, C. E., Golden, J. A., & Srivastava, A. K. (2008) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32472 · Cited by 27 · see citing works

Novel genes differentially expressed in cortical regions during late neurogenesis

Mühlfriedel, S., Kirsch, F., Gruß, P., Chowdhury, K., & Stoykova, A. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05639.x · Cited by 25 · see citing works

Brain monoaminergic neurons and ventilatory control in vertebrates

Gargaglioni, L. H., Bícego, K. C., & Branco, L. G. S. (2008) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2008.04.017 · Cited by 23 · see citing works

The brain finger protein gene (ZNF179), a member of the RING finger family, maps within the Smith-Magenis syndrome region at 17p11.2

Kimura, T., Arakawa, Y., Inoue, S., Fukushima, Y., Kondo, I., Koyama, K., Hosoi, T., Orimo, A., Muramatsu, M., Nakamura, Y., et al. (1997) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19970331)69:3 · Cited by 18 · see citing works

Expression profile of differentiating serotonin neurons derived from rhesus embryonic stem cells and comparison to adult serotonin neurons

Bethea, C. L., Reddy, A. P., Pedersen, D., & Tokuyama, Y. (2008) · Gene Expression Patterns · doi:10.1016/j.gep.2008.10.002 · Cited by 12 · see citing works

cDNA Cloning of a Human Brain Finger Protein, BFP/ZNF179, a Member of the RING Finger Protein Family

Seki, N. (1999) · DNA Research · doi:10.1093/dnares/6.5.353 · Cited by 11 · see citing works

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875 · see citing works

Transcriptomic diversity of cell types across the adult human brain

Siletti, K., Hodge, R., Mossi Albiach, A., Lee, K. W., Ding, S.-L., Hu, L., Lönnerberg, P., Bakken, T., Casper, T., Clark, M., et al. (2023) · Science · doi:10.1126/science.add7046 · Cited by 832 · see citing works

Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders

Lesch, K.-P., & Waider, J. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.013 · Cited by 435 · see citing works

Serotonin: a regulator of neuronal morphology and circuitry

Daubert, E. A., & Condron, B. G. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.05.005 · Cited by 326 · see citing works

Embracing diversity in the 5-HT neuronal system

Okaty, B. W., Commons, K. G., & Dymecki, S. M. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0151-3 · Cited by 319 · see citing works

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

Issler, O., Haramati, S., Paul, E. D., Maeno, H., Navon, I., Zwang, R., Gil, S., Mayberg, H. S., Dunlop, B. W., Menke, A., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.05.042 · Cited by 318 · see citing works

Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei

Ren, J., Isakova, A., Friedmann, D., Zeng, J., Grutzner, S. M., Pun, A., Zhao, G. Q., Kolluru, S. S., Wang, R., Lin, R., et al. (2019) · eLife · doi:10.7554/elife.49424 · Cited by 304 · see citing works

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

Hu, H., Haas, S. A., Chelly, J., Esch, H. V., Raynaud, M., de Brouwer, A. P. M., Weinert, S., Froyen, G., Frints, S. G. M., Laumonnier, F., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.193 · Cited by 298 · see citing works

Selective p38α MAPK Deletion in Serotonergic Neurons Produces Stress Resilience in Models of Depression and Addiction

Bruchas, M. R., Schindler, A. G., Shankar, H., Messinger, D. I., Miyatake, M., Land, B. B., Lemos, J. C., Hagan, C. E., Neumaier, J. F., Quintana, A., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.011 · Cited by 266 · see citing works

Central respiratory chemoreception

Guyenet, P. G., Stornetta, R. L., & Bayliss, D. A. (2010) · The Journal of Comparative Neurology · doi:10.1002/cne.22435 · Cited by 249 · see citing works

Functional topography of midbrain and pontine serotonergic systems: implications for synaptic regulation of serotonergic circuits

Hale, M. W., & Lowry, C. A. (2010) · Psychopharmacology · doi:10.1007/s00213-010-2089-z · Cited by 243 · see citing works

Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

Chiu, I. M., Barrett, L. B., Williams, E. K., Strochlic, D. E., Lee, S., Weyer, A. D., Lou, S., Bryman, G. S., Roberson, D. P., Ghasemlou, N., et al. (2014) · eLife · doi:10.7554/elife.04660 · Cited by 237 · see citing works

Multi-Scale molecular deconstruction of the serotonin neuron system

Okaty, B. W., Freret, M. E., Rood, B. D., Brust, R. D., Hennessy, M. L., deBairos, D., Kim, J. C., Cook, M. N., & Dymecki, S. M. (2015) · Neuron · doi:10.1016/j.neuron.2015.10.007 · Cited by 217 · see citing works

Probing the diversity of serotonin neurons

Gaspar, P., & Lillesaar, C. (2012) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2011.0378 · Cited by 196 · see citing works

Autism-Relevant Social Abnormalities and Cognitive Deficits in Engrailed-2 Knockout Mice

Brielmaier, J. M., Matteson, P. G., Silverman, J. L., Senerth, J. M., Kelly, S., Genestine, M., Millonig, J. H., DiCicco-Bloom, E. M., & Crawley, J. N. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040914 · Cited by 156 · see citing works

HDAC6 Regulates Glucocorticoid Receptor Signaling in Serotonin Pathways with Critical Impact on Stress Resilience

Espallergues, J., Teegarden, S. L., Veerakumar, A., Boulden, J., Challis, C., Jochems, J., Chan, M., Petersen, T. L., Deneris, E. S., Matthias, P., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5634-11.2012 · Cited by 147 · see citing works

A Genetically Defined Morphologically and Functionally Unique Subset of 5-HT Neurons in the Mouse Raphe Nuclei

Kiyasova, V., Fernández, S. P., Lainé, J., Stankovski, L., Muzerelle, A., Doly, S., & Gaspar, P. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4080-10.2011 · Cited by 138 · see citing works

Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence

Bortolato, M., & Shih, J. C. (2011) · International review of neurobiology · doi:10.1016/b978-0-12-386467-3.00002-9 · Cited by 136 · see citing works

Functional and Developmental Identification of a Molecular Subtype of Brain Serotonergic Neuron Specialized to Regulate Breathing Dynamics

Brust, R. D., Corcoran, A. E., Richerson, G. B., Nattie, E., & Dymecki, S. M. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.11.027 · Cited by 131 · see citing works

Serotonergic transcriptional networks and potential importance to mental health

Deneris, E. S., & Wyler, S. C. (2012) · Nature Neuroscience · doi:10.1038/nn.3039 · Cited by 125 · see citing works

Direct conversion of human fibroblasts to induced serotonergic neurons

Xu, Z., Jiang, H., Zhong, P., Yan, Z., Chen, S., & Feng, J. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.101 · Cited by 116 · see citing works

Development of the serotonergic cells in murine raphe nuclei and their relations with rhombomeric domains

Alonso, A., Merchán, P., Sandoval, J. E., Sánchez-Arrones, L., Garcia-Cazorla, A., Artuch, R., Ferrán, J. L., Martínez-de-la-Torre, M., & Puelles, L. (2013) · Brain Structure and Function · doi:10.1007/s00429-012-0456-8 · Cited by 113 · see citing works

Identification of serotonergic neuronal modules that affect aggressive behavior

Niederkofler, V., Asher, T. E., Okaty, B. W., Rood, B. D., Narayan, A., Hwa, L. S., Beck, S. G., Miczek, K. A., & Dymecki, S. M. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.10.063 · Cited by 113 · see citing works

Vertebrate Cone Opsins Enable Sustained and Highly Sensitive Rapid Control of G i/o Signaling in Anxiety Circuitry

Masseck, O. A., Spoida, K., Dalkara, D., Maejima, T., Rubelowski, J. M., Wallhorn, L., Deneris, E. S., & Herlitze, S. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.041 · Cited by 111 · see citing works

Serotonin neuron development: shaping molecular and structural identities

Deneris, E. S., & Gaspar, P. (2017) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.301 · Cited by 109 · see citing works

Refining the Role of 5-HT in Postnatal Development of Brain Circuits

Teissier, A., Soiza‐Reilly, M., & Gaspar, P. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00139 · Cited by 101 · see citing works

Multiscale single-cell analysis reveals unique phenotypes of raphe 5-HT neurons projecting to the forebrain

Fernandez, S. P., Cauli, B., Cabezas, C., Muzerelle, A., Poncer, J.-C., & Gaspar, P. (2016) · Brain Structure and Function · doi:10.1007/s00429-015-1142-4 · Cited by 100 · see citing works

Development of raphe serotonin neurons from specification to guidance

Kiyasova, V., & Gaspar, P. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07910.x · Cited by 98 · see citing works

Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells.

Panman, L., Andersson, E., Alekseenko, Z., Hedlund, E., Kee, N., Mong, J., Uhde, C. W., Deng, Q., Sandberg, R., Stanton, L., et al. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.04.001 · Cited by 70 · see citing works

The Disruption ofCelf6, a Gene Identified by Translational Profiling of Serotonergic Neurons, Results in Autism-Related Behaviors

Dougherty, J. D., Maloney, S. E., Wozniak, D. F., Rieger, M. A., Sonnenblick, L. I., Coppola, G., Mahieu, N. G., Zhang, J., Cai, J., Patti, G. J., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4762-12.2013 · Cited by 86 · see citing works

Trehalose-Enhanced Isolation of Neuronal Sub-Types from Adult Mouse Brain

Saxena, A., Wagatsuma, A., Noro, Y., Kuji, T., Asaka-Oba, A., Watahiki, A., Gurnot, C., Fagiolini, M., Hensch, T. K., & Carninci, P. (2012) · BioTechniques · doi:10.2144/0000113878 · Cited by 84 · see citing works

Transcriptional Control of the Terminal Fate of Monoaminergic Neurons

Flames, N., & Hobert, O. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113824 · Cited by 75 · see citing works

Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens

Black, J. B., McCutcheon, S. R., Dube, S., Barrera, A., Klann, T. S., Rice, G., Adkar, S. S., Soderling, S. H., Reddy, T. E., & Gersbach, C. A. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108460 · Cited by 71 · see citing works

The Serotonin Brainstem Hypothesis for the Sudden Infant Death Syndrome

Kinney, H. C., & Haynes, R. L. (2019) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlz062 · Cited by 70 · see citing works

The serotonergic anatomy of the developing human medulla oblongata: Implications for pediatric disorders of homeostasis

Kinney, H. C., Broadbelt, K. G., Haynes, R. L., Rognum, I. J., & Paterson, D. S. (2011) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2011.05.004 · Cited by 69 · see citing works

Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels

Maejima, T., Masseck, O. A., Mark, M. D., & Herlitze, S. (2013) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2013.00040 · Cited by 62 · see citing works

Serotonin Neuron Diversity in the Dorsal Raphe

Andrade, R., & Haj‐Dahmane, S. (2013) · ACS Chemical Neuroscience · doi:10.1021/cn300224n · Cited by 61 · see citing works

Pet-1 Switches Transcriptional Targets Postnatally to Regulate Maturation of Serotonin Neuron Excitability

Wyler, S. C., Spencer, W. C., Green, N. H., Rood, B. D., Crawford, L. K., Craige, C. P., Gresch, P. J., McMahon, D. G., Beck, S. G., & Deneris, E. S. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3798-15.2016 · Cited by 60 · see citing works

Enhancement of Stress Resilience Through Histone Deacetylase 6–Mediated Regulation of Glucocorticoid Receptor Chaperone Dynamics

Jochems, J., Teegarden, S. L., Chen, Y., Boulden, J., Challis, C., Ben-Dor, G. A., Kim, S. F., & Berton, O. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.07.036 · Cited by 57 · see citing works

Firing Properties of Genetically Identified Dorsal Raphe Serotonergic Neurons in Brain Slices

Mlinar, B., Montalbano, A., Piszczek, Ł., Gross, C. T., & Corradetti, R. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00195 · Cited by 53 · see citing works

An intuitive graphical visualization technique for the interrogation of transcriptome data

Bushati, N., Smith, J. C., Briscoe, J., & Watkins, C. J. C. H. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr462 · Cited by 52 · see citing works

5-HT1AReceptor-Mediated Autoinhibition and the Control of Serotonergic Cell Firing

Andrade, R., Huereca, D., Lyons, J. G., Andrade, E. M., & McGregor, K. M. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00034 · Cited by 52 · see citing works

Medullary serotonin neurons are CO2 sensitive in situ

Iceman, K. E., Richerson, G. B., & Harris, M. B. (2013) · Journal of Neurophysiology · doi:10.1152/jn.00288.2013 · Cited by 52 · see citing works

A new look on brain mechanisms of acute illness anorexia

Asarian, L., & Langhans, W. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.04.009 · Cited by 51 · see citing works

A neural circuit associated with anxiety‐like behaviors induced by chronic inflammatory pain and the anxiolytic effects of electroacupuncture

Wu, Z., Shen, Z., Xu, Y., Chen, S., Xiao, S., Ye, J., Zhang, H., Ma, X., Zhu, Y., Zhu, X., et al. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14520 · Cited by 47 · see citing works

Prader–Willi syndrome: From genetics to behaviour, with special focus on appetite treatments

Griggs, J. L., Sinnayah, P., & Mathai, M. L. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.10.003 · Cited by 45 · see citing works

Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm

Fox, J. H., Hassell, J. E., Siebler, P. H., Arnold, M. R., Lamb, A. K., Smith, D. G., Day, H. E. W., Smith, T. M., Simmerman, E. M., Outzen, A. A., et al. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2017.08.014 · Cited by 44 · see citing works

Modulation of rhythmic movement

Jordan, L. M., & Sławińska, U. (2011) · Progress in brain research · doi:10.1016/b978-0-444-53825-3.00017-6 · Cited by 43 · see citing works

DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders

Reif, A., Nguyen, T. T., Weissflog, L., Jacob, C., Romanos, M., Renner, T., Buttenschøn, H., Kittel-Schneider, S., Gessner, A., Weber, H., et al. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.120 · Cited by 27 · see citing works

Engrailed Is Required in Maturing Serotonin Neurons to Regulate the Cytoarchitecture and Survival of the Dorsal Raphe Nucleus

Fox, S. R., & Deneris, E. S. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5829-11.2012 · Cited by 42 · see citing works

Hox genes and region‐specific sensorimotor circuit formation in the hindbrain and spinal cord

Bonito, M. D., Glover, J. C., & Studer, M. (2013) · Developmental Dynamics · doi:10.1002/dvdy.24055 · Cited by 42 · see citing works

Identified Serotonergic Modulatory Neurons Have Heterogeneous Synaptic Connectivity within the Olfactory System of Drosophila

Coates, K. E., Majot, A. T., Zhang, X., Michael, C. T., Spitzer, S. L., Gaudry, Q., & Dacks, A. M. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.0192-17.2017 · Cited by 39 · see citing works

The Wiring Logic of an Identified Serotonergic Neuron That Spans Sensory Networks

Coates, K. E., Calle-Schuler, S. A., Helmick, L. M., Knotts, V. L., Martik, B. N., Salman, F., Warner, L. T., Valla, S. V., Bock, D. D., & Dacks, A. M. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0552-20.2020 · Cited by 36 · see citing works

Alzheimer’s Disease DNA Methylome of Pyramidal Layers in Frontal Cortex: Laser-Assisted Microdissection Study

Hernández, H. G., Sandoval-Hernández, A. G., Garrido‐Gil, P., Labandeira-García, J. L., Zelaya, M. V., Bayón, G. F., Fernández, A. F., Fraga, M. F., Arboleda, G., & Arboleda, H. (2018) · Epigenomics · doi:10.2217/epi-2017-0160 · Cited by 36 · see citing works

Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe

Haugas, M., Tikker, L., Achim, K., Salminen, M., & Partanen, J. M. (2016) · Development · doi:10.1242/dev.136614 · Cited by 34 · see citing works

Molecular genetics of mouse serotonin neurons across the lifespan

Deneris, E. S. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.061 · Cited by 32 · see citing works

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain

Forero, A., Rivero, O., Wäldchen, S., Ku, H.-P., Kiser, D. P., Gärtner, Y., Pennington, L. S., Waider, J., Gaspar, P., Jansch, C., et al. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00307 · Cited by 31 · see citing works

Serotonergic Neurosecretory Synapse Targeting Is Controlled by Netrin-Releasing Guidepost Neurons inCaenorhabditis elegans

Nelson, J. C., & Colón‐Ramos, D. A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3471-12.2012 · Cited by 29 · see citing works

Regulatory Mechanisms Controlling Maturation of Serotonin Neuron Identity and Function

Spencer, W. C., & Deneris, E. S. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00215 · Cited by 28 · see citing works

Differential activation of serotonergic neurons during short- and long-term gregarization of desert locusts

Rogers, S. M., & Ott, S. R. (2014) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2014.2062 · Cited by 25 · see citing works

Effects of chronic caffeine exposure during adolescence and subsequent acute caffeine challenge during adulthood on rat brain serotonergic systems

Arnold, M. R., Williams, P. H., McArthur, J. A., Archuleta, A. R., O’Neill, C. E., Hassell, J. E., Smith, D. G., Bachtell, R. K., & Lowry, C. A. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.12.019 · Cited by 24 · see citing works

Subset specification of central serotonergic neurons

Smidt, M. P., & van Hooft, J. A. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00200 · Cited by 23 · see citing works

STAT3 in the dorsal raphe gates behavioural reactivity and regulates gene networks associated with psychopathology

Reisinger, S. N., Sideromenos, S., Horváth, O., Derdak, S. V., Cicvaric, A., Monje, F. J., Bilban, M., Häring, M., Glat, M. J., & Pollak, D. D. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-00904-2 · Cited by 23 · see citing works

Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line

Honig, G., Liou, A., Berger, M., German, M. S., & Tecott, L. H. (2010) · Journal of Biomedical Science · doi:10.1186/1423-0127-17-82 · Cited by 23 · see citing works

Embryonic development of selectively vulnerable neurons in Parkinson’s disease

Oliveira, M. A. P., Balling, R., Smidt, M. P., & Fleming, R. M. T. (2017) · npj Parkinson s Disease · doi:10.1038/s41531-017-0022-4 · Cited by 23 · see citing works

A simplified method to generate serotonergic neurons from mouse embryonic stem and induced pluripotent stem cells

Shimada, T., Takai, Y., Shinohara, K., Yamasaki, A., Tominaga‐Yoshino, K., Ogura, A., Toi, A., Asano, K., Shintani, N., Hayata‐Takano, A., et al. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2012.07724.x · Cited by 22 · see citing works

Natural and engineered coding variation in antidepressant-sensitive serotonin transporters

Ye, R., & Blakely, R. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.056 · Cited by 21 · see citing works

Pet-1 Controls Tetrahydrobiopterin Pathway andSlc22a3Transporter Genes in Serotonin Neurons

Wyler, S. C., Donovan, L. J., Yeager, M., & Deneris, E. S. (2015) · ACS Chemical Neuroscience · doi:10.1021/cn500331z · Cited by 21 · see citing works

Evidence that preimmunization with a heat-killed preparation of Mycobacterium vaccae reduces corticotropin-releasing hormone mRNA expression in the extended amygdala in a fear-potentiated startle paradigm

Loupy, K. M., Arnold, M. R., Hassell, J. E., Lieb, M. W., Milton, L. N., Cler, K. E., Fox, J. H., Siebler, P. H., Schmidt, D., Noronha, S. I. S. R., et al. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.12.015 · Cited by 20 · see citing works

Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem

Kim, J., Kim, A., Zhao, Z., Liu, X., & Chen, Z. (2014) · Molecular Brain · doi:10.1186/1756-6606-7-48 · Cited by 19 · see citing works

Beyond Gene Inactivation: Evolution of Tools for Analysis of Serotonergic Circuitry

Hainer, C., Mosienko, V., Koutsikou, S., Crook, J. J., Gloss, B. R., Kasparov, S., Lumb, B. M., & Alenina, N. V. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00045 · Cited by 18 · see citing works

EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain

Teng, T., Gaillard, A., Muzerelle, A., & Gaspar, P. (2017) · eNeuro · doi:10.1523/eneuro.0327-16.2017 · Cited by 18 · see citing works

New tricks for an old slug: descending serotonergic system in pain.

Wei, F., Gu, M., & Chu, Y. (2012) · PubMed · Cited by 18 · see citing works

Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice

Ye, R., Carneiro, A. M. D., Airey, D., Sanders‐Bush, E., Williams, R. W., Lu, L., Wang, J., Zhang, B., & Blakely, R. (2013) · Genes Brain & Behavior · doi:10.1111/gbb.12092 · Cited by 17 · see citing works

Distinct projection targets define subpopulations of mouse brainstem vagal neurons that express the autism‐associated MET receptor tyrosine kinase

Kamitakahara, A. K., Wu, H., & Levitt, P. R. (2017) · The Journal of Comparative Neurology · doi:10.1002/cne.24294 · Cited by 16 · see citing works

Fibroblast growth factor deficiencies impact anxiety-like behavior and the serotonergic system

Brooks, L. R., Enix, C. L., Rich, S. C., Magno, J. A., Lowry, C. A., & Tsai, P. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.01.053 · Cited by 16 · see citing works

Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function

Kouwenhoven, W. M., Veenvliet, J. V., van Hooft, J. A., van der Heide, L. P., & Smidt, M. P. (2016) · Biology Open · doi:10.1242/bio.015032 · Cited by 16 · see citing works

Identifying Candidate Genes that Underlie Cellular pH Sensitivity in Serotonin Neurons Using Transcriptomics: A Potential Role for Kir5.1 Channels

Puissant, M. M., Mouradian, G. C., Liu, P., & Hodges, M. R. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00034 · Cited by 15 · see citing works

RGS2 drives male aggression in mice via the serotonergic system

Mark, M. D., Wollenweber, P., Gesk, A., Kösters, K., Batzke, K., Janoschka, C., Maejima, T., Han, J., Deneris, E. S., & Herlitze, S. (2019) · Communications Biology · doi:10.1038/s42003-019-0622-0 · Cited by 14 · see citing works

Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity

Zhang, X. L., Spencer, W. C., Tabuchi, N., Kitt, M. M., & Deneris, E. S. (2022) · eLife · doi:10.7554/elife.75970 · Cited by 14 · see citing works

RNASeq‐derived transcriptome comparisons reveal neuromodulatory deficiency in the CO2 insensitive brown Norway rat

Puissant, M. M., Echert, A. E., Yang, C., Mouradian, G. C., Novotny, T., Liu, P., Liang, M., & Hodges, M. R. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.285171 · Cited by 14 · see citing works

From B1 to B9: a guide through hindbrain serotonin neurons with additional views from multidimensional characterization

Soiza‐Reilly, M., & Gaspar, P. (2020) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-444-64125-0.00002-5 · Cited by 13 · see citing works

Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism

Grünewald, L., Landaas, E. T., Geissler, J. M., Weber, H., Quast, C., Röh, S., Schartner, C., Lesch, K., Romanos, M., Kittel‐Schneider, S., et al. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.113 · Cited by 13 · see citing works

TGF-β Signaling Regulates Development of Midbrain Dopaminergic and Hindbrain Serotonergic Neuron Subgroups

Chleilat, E., Skatulla, L., Rahhal, B., Hussein, M. T., Feuerstein, M., KRIEGLSTEIN, K. G., & Roussa, E. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.04.019 · Cited by 13 · see citing works

Large-scale identification of human cerebrovascular proteins: Inter-tissue and intracerebral vascular protein diversity

Lee, S. J., Kwon, S., Gatti, J. R., Korcari, E., Gresser, T. E., Felix, P. C., Keep, S. G., Pasquale, K. C., Bai, T., Blanchett-Anderson, S., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0188540 · Cited by 12 · see citing works

Expression of the ADHD candidate gene Diras2 in the brain

Grünewald, L., Becker, N., Camphausen, A., O’Leary, A., Lesch, K., Freudenberg, F., & Reif, A. (2018) · Journal of Neural Transmission · doi:10.1007/s00702-018-1867-3 · Cited by 11 · see citing works

Expression of RING Finger Protein 38 in Serotonergic Neurons in the Brain of Nile Tilapia, Oreochromis niloticus

Cham, K. L., Soga, T., & Parhar, I. S. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00109 · Cited by 9 · see citing works

Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons

Yan, R., Huang, T., Xie, Z., Xia, G.-N., Qian, H., Zhao, X., & Cheng, L. (2013) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmt023 · Cited by 8 · see citing works

Kappa Opioid Receptor Mediated Differential Regulation of Serotonin and Dopamine Transporters in Mood and Substance Use Disorder

Varman, D. R., Jayanthi, L. D., & Ramamoorthy, S. (2021) · Handbook of experimental pharmacology · doi:10.1007/164_2021_499 · Cited by 7 · see citing works

Cell type-specific transcriptome profiling in mammalian brains

LoVerso, P., & Cui, F. (2016) · Frontiers in Bioscience · doi:10.2741/4434 · Cited by 5 · see citing works

Cocaine reward and memory after chemogenetic inhibition of distinct serotonin neuron subtypes in mice

Baskin, B. M., Jia, J., Dymecki, S. M., & Kantak, K. M. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05560-6 · Cited by 6 · see citing works

Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons

Chleilat, E., Mallmann, R. T., Spanagel, R., Klugbauer, N., KRIEGLSTEIN, K. G., & Roussa, E. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00427 · Cited by 6 · see citing works

Tumor Spheroids of an Aggressive Form of Central Neurocytoma Have Transit-Amplifying Progenitor Characteristics with Enhanced EGFR and Tumor Stem Cell Signaling

Shin, H. Y., Han, K.-S., Park, H. W., Hong, Y. H., Kim, Y., Moon, H. E., Park, K. W., Park, H. R., Lee, C. J., Lee, K., et al. (2021) · Experimental Neurobiology · doi:10.5607/en21004 · Cited by 5 · see citing works

A human developmental and adult brain atlas benchmarks dopaminergic stem cell models and cell therapy candidatesPreprint

Bocchi, V. D., To, K., Weber, L., Zumbo, P., Kim, L., Shida, I. Y., Yang, D., Storm, P., Fiorenzano, A., Sozzi, E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.19.733041 · Cited by 4 · see citing works

Total Levels of Hippocampal Histone Acetylation Predict Normal Variability in Mouse Behavior

Nesbitt, A. M. I., McCurdy, R. D., Bryant, S. M., & Alter, M. D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094224 · Cited by 3 · see citing works

Life Without Brain Serotonin

Mosienko, V., & Alenina, N. V. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-800050-2.00020-6 · Cited by 3 · see citing works

Spatial and temporal mechanisms of cell fate determination in the developing CNS

Dias, J. M. M. (2011) · Figshare · Cited by 1 · see citing works

Fibroblast growth factor signaling in the developing serotonergic system and anxiety-related behavior

Brooks, L. R. (2014) · CU Scholar (University of Colorado Boulder)

Brain serotonin circuit reverses decline in physical activity with agePreprint

de Morentin, P. B. M., Leeson-Payne, A. T. S., Mu, S., Martynova, Y. V., Mohammadkhani, A., Neyens, D. M., Gonzalez, J. A., Lazovskis, J., Cristiano, C., Crabtree, D. R., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.27.695444

CRISPR/CAS9-MEDIATED LOSS OF VESICULAR GLUTAMATE TRANSPORTER IN SEROTONIN NEURONS OF THE DORSAL RAPHE NUCLEUS LEADS TO SYNAPTIC CHANGES AND ANXIETY-LIKE BEHAVIORSPreprint

Saidi, L., Rioux, V., Wallman, M., Rajan, S. S., Metzakopian, E., Lévesque, M., Proulx, C. D., & Parent, M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.23.707446

Multi-Scale molecular deconstruction of the serotonin neuron system

Okaty, B. W., Freret, M. E., Rood, B. D., Brust, R. D., Hennessy, M. L., deBairos, D., Kim, J. C., Cook, M. N., & Dymecki, S. M. (2015) · Neuron · doi:10.1016/j.neuron.2015.10.007 · Cited by 217 · see citing works

Molecular and Functional Characterization of Diverse Pet1 Lineage-Defined Neuron Subtypes of the Brainstem Raphe System

Freret, M. E. (2017) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Subset specification of central serotonergic neurons

Smidt, M. P., & van Hooft, J. A. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00200 · Cited by 23 · see citing works

Serotonin neuron development: shaping molecular and structural identities

Deneris, E. S., & Gaspar, P. (2017) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.301 · Cited by 109 · see citing works

Deconstructing the Brain Serotonergic System: A Transcriptomic Analysis of 5-HT Neurons Across Space and Time

Sturrock, N. J. (2021) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)