The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Alexander Disease
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### Introduction The past decade has witnessed a burst of speculation and data about how astrocyte dysfunction contributes to the phenotypes of the well known neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis, as well as other types of
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“Astrocytes may also exhibit cell-autonomous disturbances8, as happens in astrocytopathies resulting from mutated alleles of astrocytic genes (for example, GFAP in Alexander disease)9, as well as from direct viral infections or exposure to toxic substances that specifically damage astrocytes (for example, ammonium in hepatic encephalopathy)10.”
From Reactive astrocyte nomenclature, definitions, and future directions (2021) · cites this paper as [9]
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Cites
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“On the other hand, white matter astrocytes provide critical metabolic support to oligodendrocytes, which are dependent upon astroglial lactate for their homeostatic maintenance, and astrocytic exchangers for interstitial ion homeostasis (Nedergaard et al., 2003).”
BackgroundSelf-citationA Structural Scaffolding of Intermediate Filaments in Health and Disease
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Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease
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αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain
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Alexander disease: diagnosis with MR imaging.
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GFAP mutations, age at onset, and clinical subtypes in Alexander disease
Prust, M. J., Wang, J., Morizono, H., Messing, A., Brenner, M., Gordon, E., Hartka, T., Sokohl, A., Schiffmann, R., Gordish‐Dressman, H., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e3182309f72 · Cited by 264
Self-citationFatal encephalopathy with astrocyte inclusions in GFAP transgenic mice.
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Self-citationGlial Inclusions in CNS Degenerative Diseases
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Adult-onset Alexander disease: a series of eleven unrelated cases with review of the literature
Pareyson, D., Fancellu, R., Mariotti, C., Romano, S., Salmaggi, A., Carella, F., Girotti, F., Gattellaro, G., Carriero, M. R., Farina, L., et al. (2008) · Brain · doi:10.1093/brain/awn178 · Cited by 187
Tang, G., Yue, Z., Tallóczy, Z., Hagemann, T. L., Cho, W., Messing, A., Sulzer, D., & Goldman, J. E. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn042 · Cited by 176
Self-citationHagemann, T. L., Connor, J. X., & Messing, A. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3260-06.2006 · Cited by 167
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GFAP mutations in Alexander disease
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Self-citationUnusual variants of Alexander's disease
van der Knaap, M. S., Salomons, G. S., Li, R., Franzonı, E., Lg, G.-S., Smit, L. M. E., Robinson, R., Ferrie, C. D., Cree, B., Reddy, A. T., et al. (2005) · Annals of Neurology · doi:10.1002/ana.20381 · Cited by 134
Self-citationExpression Specificity of GFAP Transgenes
Su, M., Hu, H., Lee, Y., D’Azzo, A., Messing, A., & Brenner, M. (2004) · Neurochemical Research · doi:10.1007/s11064-004-6881-1 · Cited by 124
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Self-citationNationwide survey of Alexander disease in Japan and proposed new guidelines for diagnosis
The Alexander Disease Study Group in Japan, Yoshida, T., Sasaki, M., Yoshida, M., Namekawa, M., Okamoto, Y., Tsujino, S., Sasayama, H., Mizuta, I., & Nakagawa, M. (2011) · Journal of Neurology · doi:10.1007/s00415-011-6056-3 · Cited by 115
Suppression of GFAP toxicity by αB-crystallin in mouse models of Alexander disease
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Self-citationIdentification of GFAP gene mutation in hereditary adult‐onset Alexander's disease
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Self-citationAdult Alexander Disease With Autosomal Dominant Transmission
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Metadata
- Authors
- Messing, A., Brenner, M., Feany, M. B., Nedergaard, M., & Goldman, J. E.
- Affiliations
- University of Wisconsin–Madison (US)
- University of Alabama at Birmingham (US)
- University of Rochester Medicine (US)
- Columbia University (US)
- Corresponding author
- Messing, Albee
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2012-04-11
- Volume
- 32
- Issue
- 15
- Pages
- 5017-5023
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC3336214
- OpenAlex
- W4251359871
- Cited by
- 250
- References
- 55
- Citations by year
- 2026: 14 · 2025: 18 · 2024: 21 · 2023: 17 · 2022: 17 · 2021: 21 · 2020: 11 · 2019: 17 · 2018: 18 · 2017: 15 · 2016: 24 · 2015: 19 · 2014: 19 · 2013: 17 · 2012: 1
- FWCI
- 9.02
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (R01NS060120, NS-42803, NS 22475, R01NS022475, P01NS042803, NS-060120)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD 03352, P01HD076892, R03HD046599, P30HD003352)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
- Keywords
- Alexander disease, astrocyte dysfunction, neurodegenerative diseases, astrocytes, neuroinflammation
- MeSH terms
- Animals, Astrocytes, Brain, Disease Models, Animal, Glial Fibrillary Acidic Protein, Humans, Models, Neurological, Neural Pathways, Age of Onset, Alexander Disease
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