The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Alexander Disease
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### Introduction The past decade has witnessed a burst of speculation and data about how astrocyte dysfunction contributes to the phenotypes of the well known neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis, as well as other types of
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“Astrocytes may also exhibit cell-autonomous disturbances8, as happens in astrocytopathies resulting from mutated alleles of astrocytic genes (for example, GFAP in Alexander disease)9, as well as from direct viral infections or exposure to toxic substances that specifically damage astrocytes (for example, ammonium in hepatic encephalopathy)10.”
From Reactive astrocyte nomenclature, definitions, and future directions (2021) · cites this paper as [9]
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Cites
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
Rothstein, J. D., Patel, S., Regan, M. R., Haenggeli, C., Huang, Y. H., Bergles, D. E., Jin, L., Dykes Hoberg, M., Vidensky, S., Chung, D. S., et al. (2005) · Nature · doi:10.1038/nature03180 · Cited by 1,518
New roles for astrocytes: redefining the functional architecture of the brain.
Nedergaard, M., Ransom, B., & Goldman, S. A. (2003) · Trends in Neurosciences · doi:10.1016/j.tins.2003.08.008 · Cited by 1,334 · cited 1×
“On the other hand, white matter astrocytes provide critical metabolic support to oligodendrocytes, which are dependent upon astroglial lactate for their homeostatic maintenance, and astrocytic exchangers for interstitial ion homeostasis (Nedergaard et al., 2003).”
BackgroundSelf-citationA Structural Scaffolding of Intermediate Filaments in Health and Disease
Fuchs, E. V., & Cleveland, D. W. (1998) · Science · doi:10.1126/science.279.5350.514 · Cited by 1,013
Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease
Brenner, M., Johnson, T., Boespflug‐Tanguy, O., Rodriguez, D., Goldman, J. E., & Messing, A. (2001) · Nature Genetics · doi:10.1038/83679 · Cited by 698
Self-citationSheldon, A. L., & Robinson, M. B. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.03.012 · Cited by 593
αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain
Iwaki, T., Kume-Iwaki, A., Liem, R. K. H., & Goldman, J. E. (1989) · Cell · doi:10.1016/0092-8674(89)90173-6 · Cited by 549
Self-citationVesicular release of glutamate from unmyelinated axons in white matter
Ziskin, J. L., Nishiyama, A., Rubio, M. E., Fukaya, M., & Bergles, D. E. (2007) · Nature Neuroscience · doi:10.1038/nn1854 · Cited by 488
Role of plectin in cytoskeleton organization and dynamics
Wiche, G. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.17.2477 · Cited by 423
Buffo, A., Rolando, C., & Ceruti, S. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.09.014 · Cited by 338
Alexander disease: diagnosis with MR imaging.
van der Knaap, M. S., Naidu, S., Breiter, S. N., Blasér, S., Stroink, H., Springer, S., Begeer, J. C., Coster, R. V., Barth, P. G., Thomas, N. H., et al. (2001) · PubMed Central · Cited by 338
Research works printed but not linked: 1
- Rosenthal, 1898, Über eine eigenthümliche, mit syringomyelie complicirte geschwulst des rückenmarks, Bietr Pathol Anat, 23, 111
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Reactive astrocyte nomenclature, definitions, and future directions
Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-020-00783-4 · Cited by 2,513
Self-citationAstrocyte barriers to neurotoxic inflammation
Sofroniew, M. V. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3898 · Cited by 1,202
Glial fibrillary acidic protein: From intermediate filament assembly and gliosis to neurobiomarker
Yang, Z., & Wang, K. K. W. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.04.003 · Cited by 1,050
Hol, E. M., & Pekny, M. (2015) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2015.02.004 · Cited by 917
Blood GFAP as an emerging biomarker in brain and spinal cord disorders
Abdelhak, A., Foschi, M., Abu-Rumeileh, S., Yue, J. K., D’Anna, L., Huss, A., Oeckl, P., Ludolph, A. C., Kuhle, J., Petzold, A., et al. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-021-00616-3 · Cited by 807
Metadata
- Authors
- Messing, A., Brenner, M., Feany, M. B., Nedergaard, M., & Goldman, J. E.
- Affiliations
- University of Wisconsin–Madison (US)
- University of Alabama at Birmingham (US)
- University of Rochester Medicine (US)
- Columbia University (US)
- Corresponding author
- Messing, Albee
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2012-04-11
- Volume
- 32
- Issue
- 15
- Pages
- 5017-5023
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC3336214
- OpenAlex
- W4251359871
- Cited by
- 250
- References
- 55
- Citations by year
- 2026: 14 · 2025: 18 · 2024: 21 · 2023: 17 · 2022: 17 · 2021: 21 · 2020: 11 · 2019: 17 · 2018: 18 · 2017: 15 · 2016: 24 · 2015: 19 · 2014: 19 · 2013: 17 · 2012: 1
- FWCI
- 9.02
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (R01NS060120, NS-42803, NS 22475, R01NS022475, P01NS042803, NS-060120)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD 03352, P01HD076892, R03HD046599, P30HD003352)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
- Keywords
- Alexander disease, astrocyte dysfunction, neurodegenerative diseases, astrocytes, neuroinflammation
- MeSH terms
- Animals, Astrocytes, Brain, Disease Models, Animal, Glial Fibrillary Acidic Protein, Humans, Models, Neurological, Neural Pathways, Age of Onset, Alexander Disease
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