The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
GABA Concentration Is Reduced in Visual Cortex in Schizophrenia and Correlates with Orientation-Specific Surround Suppression
Open accessAbstract
The neural mechanisms underlying cognitive deficits in schizophrenia remain essentially unknown. The GABA hypothesis proposes that reduced neuronal GABA concentration and neurotransmission results in cognitive impairments in schizophrenia. However, few in vivo studies have directly examined this hypothesis. We used magnetic resonance spectroscopy (MRS) at high field to measure visual cortical GABA levels in 13 subjects with schizophrenia and 13 demographically matched healthy control subjects. We found that the schizophrenia group had an ∼10% reduction in GABA concentration. We further tested the GABA hypothesis by examining the relationship between visual cortical GABA levels and orientation-specific surround suppression (OSSS), a behavioral measure of visual inhibition thought to be dependent on GABAergic synaptic transmission. Previous work has shown that subjects with schizophrenia exhibit reduced OSSS of contrast discrimination (Yoon et al., 2009). For subjects with both MRS and OSSS data ( n = 16), we found a highly significant positive correlation ( r = 0.76) between these variables. GABA concentration was not correlated with overall contrast discrimination performance for stimuli without a surround ( r = −0.10). These results suggest that a neocortical GABA deficit in subjects with schizophrenia leads to impaired cortical inhibition and that GABAergic synaptic transmission in visual cortex plays a critical role in OSSS.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Furthermore, the authors found that this reduction predicted better (less biased) performances in the surround suppression task by observing that the lower rates of GABA observed in patients correlated with their tendency to be more accurate in contrast discrimination despite a misleading context.”
From What visual illusions teach us about schizophrenia (2014) · cites this paper as Yoon et al., 2010
Experimental — accuracy not yet measuredIn the citing paper
“and GABA-related functional deficits are seen even in their visual cortex (68–71).”
From Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons (2015) · cites this paper as [69]
In the citing paper
“Interestingly, using magnetic resonance spectroscopy, Yoon et al. revealed that patients who suffer from schizophrenia exhibited a reduced GABA concentration in the visual cortex compared with healthy controls (Yoon et al., 2010).”
From What visual illusions teach us about schizophrenia (2014) · cites this paper as Yoon et al., 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
NEURONAL CIRCUITS OF THE NEOCORTEX
Douglas, R. J., & Martin, K. A. C. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144152 · Cited by 1,886
Akbarian, S. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950160008002 · Cited by 1,002
Hashimoto, T., Volk, D. W., Eggan, S. M., Mirnics, K., Pierri, J. N., Sun, Z., Sampson, A. R., & Lewis, D. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-15-06315.2003 · Cited by 938
Circuits for local and global signal integration in primary visual cortex
Angelucci, A., Levitt, J. B., Walton, E. J. S., Hupé, J.-M., Bullier, J., & Lund, J. S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-19-08633.2002 · Cited by 789
Nature and Interaction of Signals From the Receptive Field Center and Surround in Macaque V1 Neurons
Cavanaugh, J. R., Bair, W., & Movshon, J. A. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00692.2001 · Cited by 784
Lateral inhibition between orientation detectors in the cat's visual cortex
Blakemore, C. B., & Tobin, E. (1972) · Experimental Brain Research · doi:10.1007/bf00234129 · Cited by 703
Volk, D. W., Austin, M. C., Pierri, J. N., Sampson, A. R., & Lewis, D. A. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.3.237 · Cited by 697
Impairments in frontal cortical γ synchrony and cognitive control in schizophrenia
CHO, R. Y., Konecky, R. O., & Carter, C. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609440103 · Cited by 586
Self-citationAsada, H., Kawamura, Y., Maruyama, K., Kume, H., Ding, R.-G., Kanbara, N., Kuzume, H., Sanbo, M., Yagi, T., & Obata, K. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.12.6496 · Cited by 556
Quantitation of magnetic resonance spectroscopy signals: the jMRUI software package
Stefan, D., Cesare, F. D., Andrasescu, A., Popa, E., Lazariev, A., Vescovo, E., Štrbák, O., Williams, S. R., Starčuk, Z., Cabañas, M. E., et al. (2009) · Measurement Science and Technology · doi:10.1088/0957-0233/20/10/104035 · Cited by 514
Cited by
Sorted by citations
Normalization as a canonical neural computation
Carandini, M., & Heeger, D. J. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3136 · Cited by 1,906
Interneuron dysfunction in psychiatric disorders
Marín, O. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3155 · Cited by 1,190
Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia
Lewis, D. A., Curley, A. A., Glausier, J. R., & Volk, D. W. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2011.10.004 · Cited by 1,071
Edden, R. A. E., Puts, N. A. J., Harris, A. D., Barker, P. B., & Evans, J. (2013) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24478 · Cited by 625
Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA
Mullins, P. G., McGonigle, D. J., Tuura, R., Puts, N. A. J., Vidyasagar, R., Evans, J., & Edden, R. A. E. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.12.004 · Cited by 555
In vivo magnetic resonance spectroscopy of GABA: A methodological review
Puts, N. A. J., & Edden, R. A. E. (2011) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/j.pnmrs.2011.06.001 · Cited by 394
Schür, R. R., Draisma, L. W. R., Wijnen, J. P., Boks, M. P., Koevoets, M., Joëls, M., Klomp, D. W. J., Kahn, R. S., & Vinkers, C. H. (2016) · Human Brain Mapping · doi:10.1002/hbm.23244 · Cited by 372
Krause, B., & Kadosh, R. C. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00025 · Cited by 378
Rubin, D. B., Hooser, S. D. V., & Miller, K. D. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.026 · Cited by 337
Mao, X. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1519 · Cited by 296
Curley, A. A., Arion, D., Volk, D. W., Asafu-Adjei, J. K., Sampson, A. R., Fish, K. N., & Lewis, D. A. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11010052 · Cited by 283
Alterations in cortical interneurons and cognitive function in schizophrenia
Dienel, S. J., & Lewis, D. A. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.06.020 · Cited by 281
Gaetz, W., Bloy, L., Wang, D. J., Port, R. G., Blaskey, L., Levy, S. E., & Roberts, T. P. L. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2013.05.068 · Cited by 267
MR Spectroscopic Studies of the Brain in Psychiatric Disorders
Maddock, R. J., & Buonocore, M. H. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_197 · Cited by 277
Self-citationAlterations of cortical GABA neurons and network oscillations in schizophrenia
Gonzalez-Burgos, G., Hashimoto, T., & Lewis, D. A. (2010) · Current Psychiatry Reports · doi:10.1007/s11920-010-0124-8 · Cited by 260
Krause, B., Márquez‐Ruiz, J., & Kadosh, R. C. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00602 · Cited by 280
Amblyopia and the binocular approach to its therapy
Hess, R. F., & Thompson, B. S. (2015) · Vision Research · doi:10.1016/j.visres.2015.02.009 · Cited by 264
Minzenberg, M. J., Firl, A. J., Yoon, J. H., Gomes, G. C., Reinking, C., & Carter, C. S. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.150 · Cited by 247
Self-citationGABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia
González‐Burgos, G., Fish, K. N., & Lewis, D. A. (2011) · Neural Plasticity · doi:10.1155/2011/723184 · Cited by 250
Cohen, S. M., Tsien, R. W., GOFF, D. C., & Halassa, M. M. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2014.12.026 · Cited by 249
The neurochemical profile quantified by in vivo 1H NMR spectroscopy
Duarte, J. M. N., Lei, H., Mlynárik, V., & Rolf Gruetter, A. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.12.038 · Cited by 230
Circular inferences in schizophrenia
Jardri, R., & Denève, S. (2013) · Brain · doi:10.1093/brain/awt257 · Cited by 201
The neurobiology and treatment of first-episode schizophrenia
Kahn, R. S., & Sommer, I. E. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.66 · Cited by 219
Deidda, G., Bozarth, I. F., & Cancedda, L. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00119 · Cited by 192
Krystal, J. H., Anticevic, A., Yang, G., Dragoi, G., Driesen, N. R., Wang, X., & Murray, J. D. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.01.004 · Cited by 201
GABA shapes the dynamics of bistable perception
van Loon, A. M., Knapen, T., Scholte, H. S., St. John-Saaltink, E., Donner, T. H., & Lamme, V. A. F. (2013) · Current Biology · doi:10.1016/j.cub.2013.03.067 · Cited by 189
GABA level, gamma oscillation, and working memory performance in schizophrenia
Chen, C. A., Stanford, A. D., Mao, X., Abi‐Dargham, A., Shungu, D. C., Lisanby, S. H., Schroeder, C. E., & Kegeles, L. S. (2014) · NeuroImage Clinical · doi:10.1016/j.nicl.2014.03.007 · Cited by 181
Acute Modulation of Cortical Glutamate and GABA Content by Physical Activity
Maddock, R. J., Casazza, G. A., Fernandez, D. H., & Maddock, M. I. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3455-15.2016 · Cited by 185
Self-citationSilverstein, S. M., & Rosen, R. B. (2015) · Schizophrenia Research Cognition · doi:10.1016/j.scog.2015.03.004 · Cited by 189
Big GABA: Edited MR spectroscopy at 24 research sites
Mikkelsen, M. E., Barker, P. B., Bhattacharyya, P. K., Brix, M. K., Buur, P. F., Cecil, K. M., Chan, K. L., Chen, D. Y. T., Craven, A. R., Cuypers, K., et al. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.07.021 · Cited by 184
GABAergic Mechanisms in Schizophrenia: Linking Postmortem and In Vivo Studies
de Jonge, J. C., Vinkers, C. H., Pol, H. E. H., & Marsman, A. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00118 · Cited by 203
What visual illusions teach us about schizophrenia
Notredame, C.-E., Pins, D., Deneve, S., & Jardri, R. (2014) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2014.00063 · Cited by 177
Individual Differences in Subconscious Motor Control Predicted by GABA Concentration in SMA
Boy, F., Evans, J., Edden, R. A. E., Singh, K. D., Husain, M., & Sumner, P. (2010) · Current Biology · doi:10.1016/j.cub.2010.09.003 · Cited by 179
Translating the MAM model of psychosis to humans
Modinos, G., Allen, P., Grace, A. A., & McGuire, P. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2014.12.005 · Cited by 165
Neuroimaging studies of GABA in schizophrenia: a systematic review with meta-analysis
Egerton, A., Modinos, G., Ferrera, D., & McGuire, P. K. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.124 · Cited by 162
Are hallucinations due to an imbalance between excitatory and inhibitory influences on the brain?
Jardri, R., Hugdahl, K., Hughes, M., Brunelin, J., Waters, F., Alderson-Day, B., Smailes, D., Sterzer, P., Corlett, P. R., Leptourgos, P., et al. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw075 · Cited by 157
Deficits in Transcriptional Regulators of Cortical Parvalbumin Neurons in Schizophrenia
Volk, D. W., Matsubara, T., Li, S., Sengupta, E. J., Georgiev, D. D., Minabe, Y., Sampson, A. R., Hashimoto, T., & Lewis, D. A. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12030305 · Cited by 161
Nakahara, T., Tsugawa, S., Noda, Y., Ueno, F., Honda, S., Kinjo, M., Segawa, H., Hondo, N., Mori, Y., Watanabe, H., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01297-6 · Cited by 171
A computational perspective on autism
Rosenberg, A., Patterson, J. S., & Angelaki, D. E. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1510583112 · Cited by 156
In Vivo Measurements of Glutamate, GABA, and NAAG in Schizophrenia
Rowland, L. M., Kontson, K. L., West, J., Edden, R. A. E., Zhu, H., Wijtenburg, S. A., Holcomb, H. H., & Barker, P. B. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs092 · Cited by 150
GABA and glutamate in schizophrenia: A 7 T 1H-MRS study
Marsman, A., Mandl, R. C. W., Klomp, D. W. J., Bohlken, M. M., Boer, V. O., Андрейченко, А. Е., Cahn, W., Kahn, R. S., Luijten, P. R., & Pol, H. E. H. (2014) · NeuroImage Clinical · doi:10.1016/j.nicl.2014.10.005 · Cited by 159
McNally, J. M., & McCarley, R. W. (2016) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000244 · Cited by 153
Visual Perception Disturbances in Schizophrenia: A Unified Model
Silverstein, S. M. (2016) · Nebraska Symposium on Motivation/The Nebraska symposium on motivation · doi:10.1007/978-3-319-30596-7_4 · Cited by 147
Which “neural activity” do you mean? fMRI, MEG, oscillations and neurotransmitters
Singh, K. D. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.01.028 · Cited by 141
Boy, F., Evans, J., Edden, R. A. E., Lawrence, A. D., Singh, K. D., Husain, M., & Sumner, P. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.05.030 · Cited by 141
Glutamate-glutamine and GABA in brain of normal aged and patients with cognitive impairment
Huang, D., Liu, D., Yin, J., Qian, T., Shrestha, S., & Ni, H. (2016) · European Radiology · doi:10.1007/s00330-016-4669-8 · Cited by 127
GABA abnormalities in schizophrenia: A methodological review of in vivo studies
Taylor, S. F., & Tso, I. F. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.10.011 · Cited by 132
Yoon, J. H., Grandelis, A., & Maddock, R. J. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1970-16.2016 · Cited by 130
Self-citationTadin, D., Silvanto, J., Pascual‐Leone, Á., & Battelli, L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4121-10.2011 · Cited by 120
Visual Surround Suppression in Schizophrenia
Tibber, M. S., Anderson, E. J., Bobin, T., Antonova, E., Seabright, A., Wright, B., Carlin, P., Shergill, S. S., & Dakin, S. C. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00088 · Cited by 116
About individual differences in vision
Grzeczkowski, L., Clarke, A., Francis, G., Mast, F. W., & Herzog, M. H. (2017) · Vision Research · doi:10.1016/j.visres.2016.10.006 · Cited by 120
Thootkur, M., Kraguljac, N. V., & Lahti, A. C. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.02.001 · Cited by 114
Cortical GABA Levels in Primary Insomnia
MORGAN, P. T., Pace-Schott, E. F., Mason, G. F., Forselius, E., Fasula, M. K., Valentine, G. W., & Sanacora, G. (2012) · SLEEP · doi:10.5665/sleep.1880 · Cited by 117
A Fluorescent Sensor for GABA and Synthetic GABAB Receptor Ligands
Masharina, A., Reymond, L., Maurel, D., Umezawa, K., & Johnsson, K. (2012) · Journal of the American Chemical Society · doi:10.1021/ja306320s · Cited by 112
In Vivo Measurement of GABA Transmission in Healthy Subjects and Schizophrenia Patients
Frankle, W. G., Cho, R. Y., Prasad, K. M. R., Mason, N. S., Paris, J., Himes, M. L., Walker, C. P. R., Lewis, D. A., & Narendran, R. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.14081031 · Cited by 113
Zalesky, A., Fornito, A., Egan, G. F., Pantelis, C., & Bullmore, E. T. (2011) · Human Brain Mapping · doi:10.1002/hbm.21379 · Cited by 108
Visual Masking in Schizophrenia: Overview and Theoretical Implications
Green, M. F., Lee, J., Wynn, J. K., & Mathis, K. I. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr051 · Cited by 115
Microstructural and Functional Connectivity in the Developing Preterm Brain
Lubsen, J., Vohr, B. R., Myers, E. H., Hampson, M., Lacadie, C., Schneider, K. C., Katz, K. H., Constable, R. T., & Ment, L. R. (2011) · Seminars in Perinatology · doi:10.1053/j.semperi.2010.10.006 · Cited by 117
Decreased γ-aminobutyric acid levels in the parietal region of patients with Alzheimer's disease
Bai, X., Edden, R. A. E., Gao, F., Wang, G., Wu, L., Zhao, B., Wang, M., Chan, Q., Chen, W., & Barker, P. B. (2014) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24665 · Cited by 108
Porges, E. C., Jensen, G., Foster, B. M., Edden, R. A. E., & Puts, N. A. J. (2021) · eLife · doi:10.7554/elife.62575 · Cited by 109
Visual context processing in schizophrenia
Yang, E., Tadin, D., Glasser, D. M., Hong, S. W., Blake, R., & Park, S. (2013) · Clinical Psychological Science · doi:10.1177/2167702612464618 · Cited by 104
GABA System in Schizophrenia and Mood Disorders: A Mini Review on Third-Generation Imaging Studies
Chiapponi, C., Piras, F., Piras, F., Caltagirone, C., & Spalletta, G. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00061 · Cited by 109
Rowland, L. M., Krause, B. W., Wijtenburg, S. A., McMahon, R. P., Chiappelli, J., Nugent, K. L., Nisonger, S. J., Korenic, S. A., Kochunov, P., & Hong, L. E. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.34 · Cited by 102
Decision-making in schizophrenia: A predictive-coding perspective
Sterzer, P., Voss, M., Schlagenhauf, F., & Heinz, A. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.05.074 · Cited by 105
GABA-Based Evaluation of Neurologic Conditions: MR Spectroscopy
Levy, L. M., & Degnan, A. J. (2012) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2902 · Cited by 97
Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons
Morishita, H., Cabungcal, J.-H., Chen, Y., Do, K. Q., & Hensch, T. K. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.12.026 · Cited by 92
Molecular substrates of schizophrenia: homeostatic signaling to connectivity
Landek‐Salgado, M. A., Faust, T. E., & Sawa, A. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.141 · Cited by 95
On the functions, mechanisms, and malfunctions of intracortical contextual modulation
Phillips, W. A., Clark, A., & Silverstein, S. M. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.02.010 · Cited by 94
Snijders, T. M., Milivojevic, B., & Kemner, C. (2013) · NeuroImage Clinical · doi:10.1016/j.nicl.2013.06.015 · Cited by 92
de la Fuente‐Sandoval, C., Reyes-Madrigal, F., Mao, X., León-Ortíz, P., Rodríguez-Mayoral, O., Solís‐Vivanco, R., Favila, R., Graff‐Guerrero, A., & Shungu, D. C. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv105 · Cited by 89
Ding, Z., Li, J., Spiegel, D. P., Chen, Z., Chan, L. Y. L., Luo, G., Yuan, J., Deng, D., Yu, M., & Thompson, B. S. (2016) · Scientific Reports · doi:10.1038/srep19280 · Cited by 86
The Clinical Translation of a Measure of Gain Control: The Contrast-Contrast Effect Task
Barch, D. M., Carter, C. S., Dakin, S. C., Gold, J. M., Luck, S. J., MacDonald, A. W., Ragland, J. D., Silverstein, S. M., & Strauss, M. E. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr154 · Cited by 85
Self-citationMeasuring T2 in vivo with J‐difference editing: Application to GABA at 3 tesla
Edden, R. A. E., Intrapiromkul, J., Zhu, H., Cheng, Y., & Barker, P. B. (2011) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.22865 · Cited by 84
Thakkar, K. N., Rösler, L., Wijnen, J. P., Boer, V. O., Klomp, D. W. J., Cahn, W., Kahn, R. S., & Neggers, S. F. W. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.04.007 · Cited by 82
Opposite Dynamics of GABA and Glutamate Levels in the Occipital Cortex during Visual Processing
Kurcyus, K., Birtwistle, E., Hanning, N. M., Harris, A. D., Oeltzschner, G., Edden, R. A. E., & Riedl, V. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1214-18.2018 · Cited by 84
Wijtenburg, S. A., Yang, S., Fischer, B. A., & Rowland, L. M. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.01.007 · Cited by 83
Kovács, Z., D’Agostino, D. P., Diamond, D. M., Kindy, M. S., Rogers, C. Q., & Ari, C. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00363 · Cited by 87
Kelemen, O., Kiss, I., Benedek, G., & Kéri, S. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.07.024 · Cited by 80
Phencyclidine/Schizophrenia: One View Toward the Past, The Other to the Future
Domino, E. F., & Luby, E. D. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs011 · Cited by 81
Suppression and facilitation of human neural responses
Schallmo, M., Kale, A. M., Millin, R., Flevaris, A. V., Brkanac, Z., Edden, R. A. E., Bernier, R., & Murray, S. O. (2018) · eLife · doi:10.7554/elife.30334 · Cited by 78
Sterzer, P., Mishara, A. L., Voss, M., & Heinz, A. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00502 · Cited by 76
Occipital GABA levels in older adults and their relationship to visual perceptual suppression
Pitchaimuthu, K., Wu, Q., Carter, O. L., Nguyen, B. N., Ahn, S., Egan, G. F., & McKendrick, A. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-14577-5 · Cited by 76
Phillips, W. A., & Silverstein, S. M. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00307 · Cited by 75
de la Fuente‐Sandoval, C., Reyes-Madrigal, F., Mao, X., León-Ortíz, P., Rodríguez-Mayoral, O., Jung-Cook, H. H., Solís‐Vivanco, R., Graff‐Guerrero, A., & Shungu, D. C. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.09.028 · Cited by 73
Song, C., Schwarzkopf, D. S., & Rees, G. E. (2013) · Nature Communications · doi:10.1038/ncomms3201 · Cited by 74
Aufhaus, E., Weber‐Fahr, W., Sack, M., Tunc‐Skarka, N., Oberthuer, G., Hoerst, M., Meyer‐Lindenberg, A., Boettcher, U., & Ende, G. (2012) · Magnetic Resonance in Medicine · doi:10.1002/mrm.24257 · Cited by 73
Reproducibility of prefrontal γ‐aminobutyric acid measurements with J‐edited spectroscopy
Geramita, M. A., van der Veen, J. W. C., Barnett, A. S., Farmer, A. S., Shen, J., Weinberger, D. R., & Marenco, S. (2011) · NMR in Biomedicine · doi:10.1002/nbm.1662 · Cited by 72
Suppressive mechanisms in visual motion processing: From perception to intelligence
Tadin, D. (2015) · Vision Research · doi:10.1016/j.visres.2015.08.005 · Cited by 71
Salavati, B., Rajji, T. K., Price, R., Sun, Y., Graff‐Guerrero, A., & Daskalakis, Z. J. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu132 · Cited by 71
Altered Contextual Modulation of Primary Visual Cortex Responses in Schizophrenia
Seymour, K. J., Stein, T., Sanders, L. L. O., Guggenmos, M., Theophil, I., & Sterzer, P. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.168 · Cited by 71
Violante, I. R., Ribeiro, M. J., Edden, R. A. E., Guimarães, P., Bernardino, I., Rebola, J., Cunha, G., Silva, E., & Castelo-Branco, M. S. (2013) · Brain · doi:10.1093/brain/aws368 · Cited by 74
Individual differences in GABA content are reliable but are not uniform across the human cortex
Greenhouse, I., Noah, S., Maddock, R. J., & Ivry, R. B. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.06.007 · Cited by 76
Self-citationSchwerk, A. M. K., Alves, F. D. S., Pouwels, P. J. W., & van Amelsvoort, T. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12398 · Cited by 68
CSF GABA is reduced in first-episode psychosis and associates to symptom severity
Orhan, F., Fatouros‐Bergman, H., Goiny, M., Malmqvist, A., Piehl, F., Červenka, S., Collste, K., Victorsson, P. I., Sellgren, C. M., Flyckt, L., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.25 · Cited by 66
Ribeiro, M. J., Violante, I. R., Bernardino, I., Edden, R. A. E., & Castelo-Branco, M. S. (2014) · Cortex · doi:10.1016/j.cortex.2014.10.019 · Cited by 72
Schallmo, M., Sponheim, S. R., & Olman, C. A. (2015) · Psychological Medicine · doi:10.1017/s0033291715001439 · Cited by 63
Mitchell, A., Jiang, Y., Peter, C. J., & Akbarian, S. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.10.020 · Cited by 65
Iwata, Y., Nakajima, S., Plitman, E., Mihashi, Y., Caravaggio, F., Chung, J. K., Kim, J., Gerretsen, P., Mimura, M., Remington, G. J., et al. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.03.016 · Cited by 60
Bustillo, J. (2013) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2013.15.3/jbustillo · Cited by 60
Kühn, S., Schubert, F., Mekle, R., Wenger, E., Ittermann, B., Lindenberger, U., & Gallinat, J. (2016) · Brain Structure and Function · doi:10.1007/s00429-015-1057-0 · Cited by 59
Metadata
- Authors
- Yoon, J. H., Maddock, R. J., Rokem, A., Silver, M. A., Minzenberg, M. J., Ragland, J. D., & Carter, C. S.
- Affiliations
- University of California, Davis (US)
- University of California, Berkeley (US)
- Corresponding author
- Yoon, Jong H.
- ORCID
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2010-03-10
- Volume
- 30
- Issue
- 10
- Pages
- 3777-3781
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC2846788
- OpenAlex
- W2047100861
- Cited by
- 408
- References
- 41
- Citations by year
- 2026: 13 · 2025: 9 · 2024: 21 · 2023: 23 · 2022: 23 · 2021: 27 · 2020: 17 · 2019: 35 · 2018: 18 · 2017: 33 · 2016: 31 · 2015: 34 · 2014: 28 · 2013: 38 · 2012: 22
- FWCI
- 20.50
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Eli Lilly and Company
- Pfizer
- National Alliance for Research on Schizophrenia and Depression
- National Institutes of Health
- National Institute of Mental Health (K08MH076174)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Keywords
- schizophrenia, GABA, visual cortex, cortical inhibition, GABAergic neurotransmission, contrast discrimination, cognitive impairment, magnetic resonance spectroscopy
- MeSH terms
- Adolescent, Adult, Female, gamma-Aminobutyric Acid, Humans, Male, Synaptic Transmission, Orientation, Photic Stimulation, Schizophrenia, Visual Cortex, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
