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Cited by 453

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Obesity and the pubertal transition in girls and boys

Open access
Burt Solorzano, Christine M, McCartney, Christopher R·2010·Reproduction
DOI 10.1530/rep-10-0119
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Abstract

Childhood obesity has become a major health concern in recent decades, especially with regard to metabolic abnormalities that impart a high risk for future cardiovascular disease. Recent data suggest that excess adiposity during childhood may influence pubertal development as well. In particular, excess adiposity during childhood may advance puberty in girls and delay puberty in boys. Obesity in peripubertal girls may also be associated with hyperandrogenemia and a high risk of adolescent polycystic ovary syndrome. How obesity may perturb various hormonal aspects of pubertal development remains unclear, but potential mechanisms are discussed herein. Insulin resistance and compensatory hyperinsulinemia may represent a common thread contributing to many of the pubertal changes reported to occur with childhood obesity. Our understanding of obesity's impact on pubertal development is in its infancy, and more research into pathophysiological mechanisms and longer-term sequelae is important.

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Metadata

Authors
Burt Solorzano, C. M., & McCartney, C. R.
Venue
Reproduction
Publisher
Oxford University Press (OUP)
Published
2010-09-01
Volume
140
Issue
3
Pages
399-410
ISSN
  • 1470-1626 (ISSN-L)
  • 1741-7899
DOI
10.1530/rep-10-0119
OpenAlex
W1974716906
Cited by
453
References
12
FWCI
21.81
Type
journal article
Language
en
Open access
bronze

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