Notes from the Field: Transmission of Pan-Resistant and Echinocandin-Resistant Candida auris in Health Care Facilities ― Texas and the District of Columbia, January–April 2021
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The first instance of transmission of echinocandin resistance in C. auris was reported with the emergence of pan-resistant C. auris in US healthcare settings.
“The first instance of transmission of echinocandin resistance in C. auris was reported with the emergence of pan-resistant C. auris in US healthcare settings [16].”
From Host–Candida auris interactions in the skin (2026) · cites this paper as [16]
The concluding paragraph of “Notes from the Field” (page not provided) calls the U.S. health care clusters the first evidence suggesting that pan- or echinocandin-resistant C. auris might have been transmitted. The claim omits that uncertainty and presents transmission as established. (LLM, conf=0.84)
Experimental — accuracy not yet measuredThese patients all had prior epidemiological links to health care facilities but no prior echinocandin exposure.
“It is important to note that these patients all had prior epidemiological links to health care facilities but no prior echinocandin exposure (32).”
From Clinical Efficacy and Safety of a Novel Antifungal, Fosmanogepix, in Patients with Candidemia Caused by Candida auris <i>:</i> Results from a Phase 2 Trial (2023) · cites this paper as [32]
Some Candida auris isolates are pan-drug-resistant, tolerating all available antifungal drugs.
“Recently, some C. auris isolates were classified as pan-drug-resistant, tolerating all available antifungal drugs [12,13].”
From Lansoprazole interferes with fungal respiration and acts synergistically with amphotericin B against multidrug-resistant <i>Candida auris</i> (2024) · cites this paper as [13]
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- Authors
- Lyman, M., Forsberg, K., Reuben, J., Dang, T., Free, R., Seagle, E. E., Sexton, D. J., Soda, E., Jones, H., Hawkins, D., Anderson, A., Bassett, J., Lockhart, S. R., Merengwa, E., Iyengar, P., Jackson, B. R., & Chiller, T.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Digital China Health (China) (CN)
- Texas Department of State Health Services (US)
- Corresponding author
- Lyman, Meghan
- ORCID
- Venue
- MMWR. Morbidity and Mortality Weekly Report
- Published
- 2021-07-23
- Volume
- 70
- Issue
- 29
- Pages
- 1022-1023
- ISSN
- 0149-2195 (ISSN-L)
- 1545-861X
- PMC
- PMC8297693
- OpenAlex
- W3186384872
- Cited by
- 104
- References
- 6
- Citations by year
- 2026: 19 · 2025: 12 · 2024: 20 · 2023: 23 · 2022: 20 · 2021: 10
- FWCI
- 5.78
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- MMWR Morbidity and Mortality Weekly Report (publishedVersion)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
- Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
- Keywords
- Candida auris, echinocandin resistance, fungemia, nosocomial transmission, healthcare facilities, antimicrobial resistance, Texas, Washington, D.C.
- MeSH terms
- Amphotericin B, Antifungal Agents, Azoles, Candida, Cross Infection, District of Columbia, Humans, Texas, Drug Resistance, Multiple, Fungal, Echinocandins, Candidiasis, Invasive
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