Fetal androgen excess provides a developmental origin for polycystic ovary syndrome
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Our 14-year study of a nonhuman primate model for polycystic ovary syndrome (PCOS) has provided substantial, experimentally derived evidence for fetal origins of PCOS that leads to lifelong reprodu...
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Prenatal androgen exposure may play a role in the pathogenesis of PCOS-like syndromes in animal models.
“Extensive experimental evidence suggests that prenatal androgen exposure may play a role in the pathogenesis of PCOS-like syndromes in animal models [19,44,45,46].”
From Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment (2022) · cites this paper as [45]
In utero genomic programming of metabolic and endocrine pathways can increase the susceptibility of offspring to develop PCOS following exposure to specific nutritional and environmental conditions.
“In utero genomic programming of metabolic and endocrine pathways can increase the susceptibility of offspring to develop PCOS following exposure to specific nutritional and environmental conditions [45].”
From Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment (2022) · cites this paper as [45]
This research has resulted in a proposed two hit hypothesis for the development of PCOS phenotypes.
“This research has resulted in a proposed “two hit” hypothesis for the development of PCOS phenotypes [43,45].”
From Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment (2022) · cites this paper as [45]
Cites
(2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.10.004 · Cited by 9,050 · see citing works
The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group (2004) · Human Reproduction · doi:10.1093/humrep/deh098 · Cited by 6,138 · see citing works
Franks, S. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509283331307 · Cited by 2,463 · see citing works
Azziz, R., Carmina, E., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Futterweit, W., Janssen, O. E., Legro, R. S., Norman, R. J., Taylor, A. E., et al. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.06.035 · Cited by 2,132 · see citing works
Norman, R. J., Dewailly, D., Legro, R. S., & Hickey, T. E. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61345-2 · Cited by 1,360 · see citing works
Lawrence, J., Douglas, P., & Gandy, J. (2016) · doi:10.1002/9781119163411.ch73 · Cited by 1,014 · see citing works
A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome
Boomsma, C. M., Eijkemans, M. J. C., Hughes, E. G., Visser, G. H. A., Fauser, B. C. J. M., & Macklon, N. S. (2006) · Human Reproduction Update · doi:10.1093/humupd/dml036 · Cited by 852 · see citing works
Heritability of polycystic ovary syndrome in a Dutch twin-family study
Vink, J. M., Sadrzadeh, S., Lambalk, C. B., & Boomsma, D. I. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1494 · Cited by 647 · see citing works
Abbott, D. H., Barnett, D. K., Bruns, C. M., & Dumesic, D. A. (2005) · Human Reproduction Update · doi:10.1093/humupd/dmi013 · Cited by 555 · see citing works
Self-citationGranulosa Cell Production of Anti-Müllerian Hormone Is Increased in Polycystic Ovaries
Pellatt, L. J., Hanna, L., Brincat, M., Galea, R., Brain, H., Whitehead, S. A., & Mason, H. D. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1582 · Cited by 518 · see citing works
Developmental origin of polycystic ovary syndrome—a hypothesis
Abbott, D., Dumesic, D., & Franks, S. (2002) · Journal of Endocrinology · doi:10.1677/joe.0.1740001 · Cited by 504 · see citing works
Self-citationPolycystic ovary syndrome and cardiovascular disease: a premature association?
Legro, R. S. (2003) · Endocrine Reviews · doi:10.1210/er.2003-0004 · Cited by 466 · see citing works
Coviello, A. D., Legro, R. S., & Dunaif, A. E. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1666 · Cited by 446 · see citing works
Broekmans, F. J., Knauff, E. A. H., Valkenburg, O., Laven, J. S. E., Eijkemans, M. J. C., & Fauser, B. C. J. M. (2006) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2006.01008.x · Cited by 445 · see citing works
Insulin resistance, polycystic ovary syndrome, and type 2 diabetes mellitus
Ovalle, F., & Azziz, R. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)03111-4 · Cited by 428 · see citing works
Polycystic ovary syndrome and endometrial carcinoma
Hardiman, P. J., Pillay, O., & Atiomo, W. (2003) · The Lancet · doi:10.1016/s0140-6736(03)13409-5 · Cited by 414 · see citing works
Sir‐Petermann, T. (2002) · Human Reproduction · doi:10.1093/humrep/17.10.2573 · Cited by 412 · see citing works
(1997) · PubMed · Cited by 363 · see citing works
Sullivan, S. D., & Moenter, S. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308058101 · Cited by 309 · see citing works
Wood, J. R., Dumesic, D. A., Abbott, D. H., & Strauss, J. F. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2123 · Cited by 307 · see citing works
Self-citationBarnes, R. B., Rosenfield, R. L., Ehrmann, D. A., Cara, J. F., Cuttler, L., Levitsky, L. L., & Rosenthal, I. M. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.79.5.7962325 · Cited by 304 · see citing works
The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome
Blank, S. K., McCartney, C. R., & Marshall, J. C. (2006) · Human Reproduction Update · doi:10.1093/humupd/dml017 · Cited by 301 · see citing works
Goy, R. W. (1988) · Hormones and Behavior · doi:10.1016/0018-506x(88)90058-x · Cited by 294 · see citing works
Identifying Children at Risk for Polycystic Ovary Syndrome
Rosenfield, R. L. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2012 · Cited by 288 · see citing works
In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development
Goto, M. (2006) · Journal of Clinical Investigation · doi:10.1172/jci25091 · Cited by 284 · see citing works
Polycystic ovary syndrome and its developmental origins
Dumesic, D. A., Abbott, D. H., & Padmanabhan, V. (2007) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-007-9046-0 · Cited by 283 · see citing works
Self-citationYıldız, B. O., Yaralı́, H., Oğuz, H., & Bayraktar, M. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021499 · Cited by 273 · see citing works
Adolescent Obesity and Puberty: The “Perfect Storm”
Jasik, C. B., & Lustig, R. H. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1429.009 · Cited by 265 · see citing works
Manikkam, M., Crespi, E. J., Doop, D. D., Herkimer, C., Lee, J. S., Yu, S., Brown, M. B., Foster, D. L., & Padmanabhan, V. (2003) · Endocrinology · doi:10.1210/en.2003-0478 · Cited by 254 · see citing works
Extracellular matrix of the developing ovarian follicle
Rodgers, R., Irving-Rodgers, H., & Russell, D. (2003) · Reproduction · doi:10.1530/rep.0.1260415 · Cited by 253 · see citing works
Fetal growth, length of gestation, and polycystic ovaries in adult life
Cresswell, J., Barker, D., Osmond, C., Egger, P., Phillips, D., & Fraser, R. (1997) · The Lancet · doi:10.1016/s0140-6736(97)06062-5 · Cited by 241 · see citing works
Jakimiuk, A. J., Weitsman, S. R., Navab, A., & Magoffin, D. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.3.7318 · Cited by 234 · see citing works
Abbott, D. H., Dumesic, D. A., Eisner, J. R., Colman, R. J., & Kemnitz, J. W. (1998) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(98)00019-8 · Cited by 228 · see citing works
Self-citationBirth weight in offspring of mothers with polycystic ovarian syndrome
Sir‐Petermann, T., Hitchsfeld, C., Maliqueo, M. A., Ethel Codner, D., Echiburú, B., Gazitúa, R., Recabarren, S. E., & CASSORLA, F. G. (2005) · Human Reproduction · doi:10.1093/humrep/dei009 · Cited by 211 · see citing works
Polycystic ovary syndrome in adolescents
Franks, S. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.61 · Cited by 210 · see citing works
Hagenfeldt, K., Janson, P. O., Holmdahl, G., Falhammar, H., Filipsson, H., Frisen, L., Thoren, M., & Nordenskjold, A. (2008) · Human Reproduction · doi:10.1093/humrep/den118 · Cited by 205 · see citing works
An update of congenital adrenal hyperplasia
NEW, M. I. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1315.009 · Cited by 178 · see citing works
Abbott, D. H., Tarantal, A. F., & Dumesic, D. A. (2009) · American Journal of Primatology · doi:10.1002/ajp.20679 · Cited by 177 · see citing works
Self-citationPrenatal testosterone and gender-related behaviour
Hines, M. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02236 · Cited by 173 · see citing works
Eisner, J. R., Dumesic, D. A., Kemnitz, J. W., & Abbott, D. H. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.3.6453 · Cited by 173 · see citing works
Self-citationFoecking, E. M., Szabo, M., Schwartz, N. B., & Levine, J. E. (2005) · Biology of Reproduction · doi:10.1095/biolreprod.105.039800 · Cited by 165 · see citing works
van Hooff, M. H. A. (2004) · Human Reproduction · doi:10.1093/humrep/deh079 · Cited by 162 · see citing works
Body size from birth to adulthood as a predictor of self-reported polycystic ovary syndrome symptoms
Laitinen, J., Taponen, S., Martikainen, H. K., Pouta, A., Millwood, I. Y., Hartikainen, A., Ruokonen, A., Sovio, U., McCarthy, M. I., Franks, S., et al. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802301 · Cited by 160 · see citing works
Beck‐Peccoz, P., Padmanabhan, V., Baggiani, A., CORTELAZZI, D., Buscaglia, M., MEDRI, G., Marconi, A. M., Pardi, G., & Beitins, I. Z. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-3-525 · Cited by 139 · see citing works
Increased Adiposity in Female Rhesus Monkeys Exposed to Androgen Excess During Early Gestation
Eisner, J. R., Dumesic, D. A., Kemnitz, J. W., Colman, R. J., & Abbott, D. H. (2003) · Obesity Research · doi:10.1038/oby.2003.42 · Cited by 133 · see citing works
Self-citationIntra-follicular activin availability is altered in prenatally-androgenized lambs
West, C. R., Foster, D. L., Evans, N. P., Robinson, J. E., & Padmanabhan, V. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00632-3 · Cited by 116 · see citing works
Urbanek, M., Sam, S., Legro, R. S., & Dunaif, A. E. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0761 · Cited by 111 · see citing works
Dumesic, D. A., Schramm, R. D., Peterson, E., Paprocki, A. M., Zhou, R., & Abbott, D. H. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.3.8287 · Cited by 105 · see citing works
Self-citationHuman ovarian theca cells in culture
Wickenheisser, J. K., Nelson-DeGrave, V. L., & McAllister, J. M. (2006) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2006.01.003 · Cited by 102 · see citing works
Abbott, D. H., Barnett, D. K., Levine, J. E., Padmanabhan, V., Dumesic, D. A., Jacoris, S., & Tarantal, A. F. (2008) · Biology of Reproduction · doi:10.1095/biolreprod.108.067702 · Cited by 102 · see citing works
Self-citationHerman, R. A., Jones, B., Mann, D. R., & Wallen, K. (2000) · Hormones and Behavior · doi:10.1006/hbeh.2000.1608 · Cited by 101 · see citing works
Extracellular Matrix of the Developing Ovarian Follicle
Irving‐Rodgers, H. F., & Rodgers, R. J. (2006) · Seminars in Reproductive Medicine · doi:10.1055/s-2006-948549 · Cited by 99 · see citing works
Oocyte quality in polycystic ovaries revisited: Identification of a particular subgroup of women
Cano, F., García-Velasco, J. A., Millet, A., Remohi, J. A., Simón, C., & Pellicer, A. (1997) · Journal of Assisted Reproduction and Genetics · doi:10.1007/bf02765826 · Cited by 97 · see citing works
Sexual Differentiation and Feedback Control of Luteinizing Hormone Secretion in the Rhesus Monkey1
Steiner, R. A., Clifton, D. K., Spies, H. G., & Resko, J. A. (1976) · Biology of Reproduction · doi:10.1095/biolreprod15.2.206 · Cited by 91 · see citing works
Sadrzadeh, S. A. (2003) · Human Reproduction · doi:10.1093/humrep/deg409 · Cited by 89 · see citing works
Zehr, J. L., Meter, P. E. V., & Wallen, K. (2005) · Biology of Reproduction · doi:10.1095/biolreprod.104.027755 · Cited by 87 · see citing works
Insulin Resistance and Impaired Insulin Secretion in Prenatally Androgenized Male Rhesus Monkeys
Bruns, C. M., Baum, S. T., Colman, R. J., Eisner, J. R., Kemnitz, J. W., Weindruch, R. H., & Abbott, D. H. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0918 · Cited by 86 · see citing works
Self-citationVariations in Adrenal Androgen Production Among (Nonhuman) Primates
Conley, A. J., Pattison, J. C., & Bird, I. M. (2004) · Seminars in Reproductive Medicine · doi:10.1055/s-2004-861548 · Cited by 83 · see citing works
Zhou, R., Bird, I. M., Dumesic, D. A., & Abbott, D. H. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0691 · Cited by 80 · see citing works
Self-citationMetabolic Phenotype in the Brothers of Women with Polycystic Ovary Syndrome
Sam, S., Coviello, A. D., Sung, Y., Legro, R. S., & Dunaif, A. E. (2008) · Diabetes Care · doi:10.2337/dc07-2190 · Cited by 80 · see citing works
Baron, D., Montfort, J., Houlgatte, R., Fostier, A., & Guiguen, Y. (2007) · BMC Genomics · doi:10.1186/1471-2164-8-357 · Cited by 67 · see citing works
Puberty and polycystic ovary syndrome
Witchel, S. F. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.04.028 · Cited by 61 · see citing works
Human Fetal Ovary Development Involves the Spatiotemporal Expression of P450c17 Protein
Cole, B., Hensinger, K., Maciel, G. A. R., Chang, R. J., & Erickson, G. F. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0641 · Cited by 61 · see citing works
Jiang, F., & Wang, Z. (2003) · Endocrinology · doi:10.1210/en.2002-220718 · Cited by 58 · see citing works
Shapiro, E., Huang, H.-Y., & Wu, X. (2000) · The Journal of Urology · doi:10.1016/s0022-5347(05)67247-3 · Cited by 58 · see citing works
Laurich, V. M., Trbovich, A. M., O’Neill, F. H., Houk, C. P., Sluss, P. M., Payne, A. H., Donahoe, P. K., & Teixeira, J. M. (2002) · Endocrinology · doi:10.1210/en.2001-211352 · Cited by 55 · see citing works
Foong, S. C., Abbott, D. H., Zschunke, M. A., Lesnick, T. G., Phy, J. L., & Dumesic, D. A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2142 · Cited by 53 · see citing works
Self-citationZhou, R., Bruns, C. M., Bird, I. M., Kemnitz, J. W., Goodfriend, T. L., Dumesic, D. A., & Abbott, D. H. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2006.12.009 · Cited by 48 · see citing works
Self-citationPrenatal testosterone propionate and postnatal ovarian activity in the rat
Slob, A. K., Hamer, R., Woutersen, P. J. A., & ten Bosch, J. J. V. D. W. (1983) · European Journal of Endocrinology · doi:10.1530/acta.0.1030420 · Cited by 44 · see citing works
Bruns, C. M., Baum, S. T., Colman, R. J., Dumesic, D. A., Eisner, J., Jensen, M. D., Whigham, L. D., & Abbott, D. H. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803638 · Cited by 44 · see citing works
Self-citationEllinwood, W. E., Baughman, W. L., & Resko, J. A. (1982) · Endocrinology · doi:10.1210/endo-110-1-183 · Cited by 42 · see citing works
Manlove, H. A., Guillermo, C. J., & Gray, P. B. (2008) · Annals of Human Biology · doi:10.1080/03014460802337067 · Cited by 35 · see citing works
Structural and regulatory macromolecules in sex differentiation of gonads
Pelliniemi, L. J., & Fröjdman, K. (2001) · Journal of Experimental Zoology · doi:10.1002/jez.1096 · Cited by 35 · see citing works
Polycystic Ovary Syndrome with Endometrial Hyperplasia in a Cynomolgus Monkey (Macaca fascicularis)
Arifin, E., Shively, C. A., Register, T. C., & Cline, J. M. (2008) · Veterinary Pathology · doi:10.1354/vp.45-4-512 · Cited by 34 · see citing works
France, J. T., Mason, J. I., Magness, R. R., Murry, B. A., & Rosenfeld, C. R. (1987) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(87)90371-2 · Cited by 32 · see citing works
Estradiol Synthesis by Fetal Monkey Ovaries Correlates with Antral Follicle Formation 1
Ellinwood, W. E., McClellan, M. C., Brenner, R., & Resko, J. A. (1983) · Biology of Reproduction · doi:10.1095/biolreprod28.2.505 · Cited by 29 · see citing works
Foong, S. C., Abbott, D. H., Lesnick, T. G., Session, D. R., Walker, D. L., & Dumesic, D. A. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.11.041 · Cited by 17 · see citing works
Self-citationSMAD3 inhibits SF-1-dependent activation of the CYP17 promoter in H295R cells
Derebecka, N., Lehmann, T. P., Hołysz, M., & Trzeciak, W. H. (2007) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-007-9585-4 · Cited by 13 · see citing works
Arnaud, J., Brun, H., Llobera, R., & Constans, J. (1991) · Annals of Human Biology · doi:10.1080/03014469100001352 · Cited by 10 · see citing works
Polycystic ovary syndrome as a developmental disorder
Goverde, A. J., Westerveld, H. E., Veltman-Verhulst, S. M., & Fauser, B. C. J. M. (2008) · Expert Review of Obstetrics & Gynecology · doi:10.1586/17474108.3.6.775 · Cited by 8 · see citing works
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Homburg, R. (2009) · Human Reproduction · doi:10.1093/humrep/dep049 · Cited by 134 · see citing works
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parker, J., O'Brien, C., Hawrelak, J., & Gersh, F. (2021) · doi:10.20944/preprints202112.0088.v1 · Cited by 113 · see citing works
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“In utero genomic programming of metabolic and endocrine pathways can increase the susceptibility of offspring to develop PCOS following exposure to specific nutritional and environmental conditions [45].”
BackgroundInfluentialAbbott, D. H., Bruns, C. M., Barnett, D. K., Dunaif, A. E., Goodfriend, T. L., Dumesic, D. A., & Tarantal, A. F. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00058.2010 · Cited by 97 · see citing works
Self-citationHogg, K., Young, J. M., Oliver, E. M., de Souza, C. J. H., McNeilly, A. S., & Duncan, W. C. (2011) · Endocrinology · doi:10.1210/en.2011-1607 · Cited by 64 · see citing works
Hogg, K., McNeilly, A. S., & Duncan, W. C. (2011) · Endocrinology · doi:10.1210/en.2010-1219 · Cited by 62 · see citing works
Lightner, D. J., Fox, J. A., & Klingele, C. J. (2010) · Urology · doi:10.1016/j.urology.2009.12.061 · Cited by 55 · see citing works
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- Authors
- Abbott, D. H., & Dumesic, D. A.
- Affiliations
- University of Wisconsin–Madison (US)
- Venue
- Expert Review of Obstetrics & Gynecology
- Publisher
- Informa UK Limited
- Published
- 2009-01
- Volume
- 4
- Issue
- 1
- Pages
- 1-7
- ISSN
- 1747-4108 (ISSN-L)
- 1747-4116
- OpenAlex
- W2123772566
- Cited by
- 11
- References
- 80
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Expert Review of Obstetrics & Gynecology (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Keywords
- polycystic ovary syndrome, developmental origins of health and disease, nonhuman primate model, fetal programming, androgen exposure, reproductive health
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