Cited by 12Ovarian function and disordersSexual Differentiation and DisordersReproductive Biology and Fertility

Fetal androgen excess provides a developmental origin for polycystic ovary syndrome

Open access
Abbott, David H, Dumesic, Daniel A·2009·Expert Review of Obstetrics & Gynecology

Abstract

Our 14-year study of a nonhuman primate model for polycystic ovary syndrome (PCOS) has provided substantial, experimentally derived evidence for fetal origins of PCOS that leads to lifelong reprodu...

Integrity signals

Registry

Crossref · 10.1586/17474108.4.1.1

Cites

80 of 80 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Prenatal androgen exposure may play a role in the pathogenesis of PCOS-like syndromes in animal models.

    “Extensive experimental evidence suggests that prenatal androgen exposure may play a role in the pathogenesis of PCOS-like syndromes in animal models [19,44,45,46].”
  • In utero genomic programming of metabolic and endocrine pathways can increase the susceptibility of offspring to develop PCOS following exposure to specific nutritional and environmental conditions.

    “In utero genomic programming of metabolic and endocrine pathways can increase the susceptibility of offspring to develop PCOS following exposure to specific nutritional and environmental conditions [45].”
  • This research has resulted in a proposed two hit hypothesis for the development of PCOS phenotypes.

    “This research has resulted in a proposed “two hit” hypothesis for the development of PCOS phenotypes [43,45].”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Abbott, D. H., & Dumesic, D. A.
Affiliations
University of Wisconsin–Madison (US)
Venue
Expert Review of Obstetrics & Gynecology
Published
2009-01
Volume
4
Issue
1
Pages
1-7
ISSN
  • 1747-4108 (ISSN-L)
  • 1747-4116
OpenAlex
W2123772566
Cited by
11
References
80
Citations by year
2026: 2 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1
FWCI
1.93
Type
journal article
Language
en
Open access
Locations
Expert Review of Obstetrics & Gynecology (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
Keywords
polycystic ovary syndrome, developmental origins of health and disease, nonhuman primate model, fetal programming, androgen exposure, reproductive health

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review