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Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing
Abstract
MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle, ligament, tendon, and adipose. MSCs are rare in bone marrow, representing ∼1 in 10,000 nucleated cells. Although not immortal, they have the ability to expand manyfold in culture while retaining their growth and multilineage potential. MSCs are identified by the expression of many molecules including CD105 (SH2) and CD73 (SH3/4) and are negative for the hematopoietic markers CD34, CD45, and CD14. The properties of MSCs make these cells potentially ideal candidates for tissue engineering. It has been shown that MSCs, when transplanted systemically, are able to migrate to sites of injury in animals, suggesting that MSCs possess migratory capacity. However, the mechanisms underlying the migration of these cells remain unclear. Chemokine receptors and their ligands and adhesion molecules play an important role in tissue-specific homing of leukocytes and have also been implicated in trafficking of hematopoietic precursors into and through tissue. Several studies have reported the functional expression of various chemokine receptors and adhesion molecules on human MSCs. Harnessing the migratory potential of MSCs by modulating their chemokine-chemokine receptor interactions may be a powerful way to increase their ability to correct inherited disorders of mesenchymal tissues or facilitate tissue repair in vivo. The current review describes what is known about MSCs and their capacity to home to tissues together with the associated molecular mechanisms involving chemokine receptors and adhesion molecules. Disclosure of potential conflicts of interest is found at the end of this article.
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1 retracted
Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells
Reyes, M., Lund, T., Lenvik, T., Aguiar, D., Koodie, L., & Verfaillie, C. M. (2001) · Blood · doi:10.1182/blood.v98.9.2615 · Cited by 1,185
RetractedMultilineage potential of adult human mesenchymal stem cells
Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052
Human Adipose Tissue Is a Source of Multipotent Stem Cells
Zuk, P. A., Zhu, M., Ashjian, P., De Ugarte, D. A., Huang, J. I., Mizuno, H., Alfonso, Z. C., Fraser, J. K., Benhaim, P., & Hedrick, M. H. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-02-0105 · Cited by 6,664
Caplan, A. I. (1991) · Journal of Orthopaedic Research · doi:10.1002/jor.1100090504 · Cited by 6,548
Bone marrow cells regenerate infarcted myocardium
Orlic, D., Kajstura, J., Chimenti, S., Jakoniuk, I., Anderson, S. M., Li, B., Pickel, J., McKay, R., Nadal-Ginard, B., Bodine, D. M., et al. (2001) · Nature · doi:10.1038/35070587 · Cited by 5,155
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
Prockop, D. J. (1997) · Science · doi:10.1126/science.276.5309.71 · Cited by 4,629
Human mesenchymal stem cells modulate allogeneic immune cell responses
Aggarwal, S., & Pittenger, M. F. (2005) · Blood · doi:10.1182/blood-2004-04-1559 · Cited by 4,511
Di Nicola, M., Carlo-Stella, C., Magni, M., Milanesi, M., Longoni, P. D., Matteucci, P., Grisanti, S., & Gianni, A. M. (2002) · Blood · doi:10.1182/blood.v99.10.3838 · Cited by 3,226
Le Blanc, K., Rasmusson, I., Sundberg, B., Götherström, C., Hassan, M., Uzunel, M., & Ringdén, O. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16104-7 · Cited by 2,734
Chemokines and leukocyte traffic
Baggiolini, M. (1998) · Nature · doi:10.1038/33340 · Cited by 2,709
The many roles of chemokines and chemokine receptors in inflammation
Charo, I. F., & Ransohoff, R. M. (2006) · New England Journal of Medicine · doi:10.1056/nejmra052723 · Cited by 2,523
Adult rat and human bone marrow stromal cells differentiate into neurons
Woodbury, D., Schwarz, E. J., Prockop, D. J., & Black, I. B. (2000) · Journal of Neuroscience Research · doi:10.1002/1097-4547(20000815)61:4<364::aid-jnr2>3.0.co;2-c · Cited by 2,434
Bartholomew, A., Sturgeon, C., Siatskas, M., Ferrer, K., McIntosh, K., Patil, S., Hardy, W., Devine, S., Ucker, D., Deans, R., et al. (2002) · Experimental Hematology · doi:10.1016/s0301-472x(01)00769-x · Cited by 2,295
Mobilized bone marrow cells repair the infarcted heart, improving function and survival
Orlic, D., Kajstura, J., Chimenti, S., Limana, F., Jakoniuk, I., Quaini, F., Nadal-Ginard, B., Bodine, D. M., Leri, A., & Anversa, P. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.181177898 · Cited by 2,086
A new class of membrane-bound chemokine with a CX3C motif
Bazan, J. F., Bacon, K. B., Hardiman, G., Wang, W., Soo, K., Rossi, D., Greaves, D. R., Zlotnik, A., & Schall, T. J. (1997) · Nature · doi:10.1038/385640a0 · Cited by 2,013
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
Jackson, K. A., Majka, S. M., Wang, H., Pocius, J., Hartley, C. J., Majesky, M. W., Entman, M. L., Michael, L. H., Hirschi, K. K., & Goodell, M. A. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12150 · Cited by 1,960
Horwitz, E. M., Prockop, D. J., Fitzpatrick, L. A., Koo, W. W. K., Gordon, P. L., Neel, M., Sussman, M., Orchard, P., Marx, J. C., Pyeritz, R. E., et al. (1999) · Nature Medicine · doi:10.1038/6529 · Cited by 1,824
Human mesenchymal stem cells modulate B-cell functions
Corcione, A., Benvenuto, F., Ferretti, E., Giunti, D., Cappiello, V., Cazzanti, F., Risso, M., Gualandi, F., Mancardi, G. L., Pistoia, V., et al. (2006) · Blood · doi:10.1182/blood-2005-07-2657 · Cited by 1,767
Chen, J., Li, Y., Wang, L., Zhang, Z., Lu, D., Lu, M., & Chopp, M. (2001) · Stroke · doi:10.1161/01.str.32.4.1005 · Cited by 1,764
Fibroblast precursors in normal and irradiated mouse hematopoietic organs.
Friedenstein, A. J., Jf, G., & Nn, K. (1976) · PubMed · Cited by 1,658
Horwitz, E. M., Gordon, P. L., Koo, W. K. K., Marx, J. C., Neel, M. D., McNall, R. Y., Muul, L., & Hofmann, T. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.132252399 · Cited by 1,650
Kopen, G. C., Prockop, D. J., & Phinney, D. G. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.19.10711 · Cited by 1,636
Le Blanc, K., Tammik, C., Rosendahl, K., Zetterberg, E., & Ringdén, O. (2003) · Experimental Hematology · doi:10.1016/s0301-472x(03)00110-3 · Cited by 1,623
Krampera, M., Glennie, S., Dyson, J., Scott, D., Laylor, R., Simpson, E., & Dazzi, F. (2003) · Blood · doi:10.1182/blood-2002-07-2104 · Cited by 1,598
Ortiz, L. A., Gambelli, F., McBride, C., Gaupp, D., Baddoo, M., Kaminski, N., & Phinney, D. G. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432929100 · Cited by 1,445
Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
Zappia, E., Casazza, S., Pedemonte, E., Benvenuto, F., Bonanni, I., Gerdoni, E., Giunti, D., Ceravolo, A., Cazzanti, F., Frassoni, F., et al. (2005) · Blood · doi:10.1182/blood-2005-04-1496 · Cited by 1,430
Le Blanc, K., Tammik, L., Sundberg, B., Haynesworth, S. E., & Ringdén, O. (2003) · Scandinavian Journal of Immunology · doi:10.1046/j.1365-3083.2003.01176.x · Cited by 1,368
Qin, S., Rottman, J. B., Myers, P., Kassam, N., Weinblatt, M., Loetscher, M., Koch, A. E., Moser, B., & Mackay, C. R. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1422 · Cited by 1,359
Campagnoli, C., Roberts, I. A. G., Kumar, S., Bennett, P. R., Bellantuono, I., & Fisk, N. M. (2001) · Blood · doi:10.1182/blood.v98.8.2396 · Cited by 1,348
Jiang, X.-X., Zhang, Y., Liu, B., Zhang, S.-X., Wu, Y., Yu, X.-D., & Mao, N. (2005) · Blood · doi:10.1182/blood-2004-02-0586 · Cited by 1,346
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
Petit, I., Szyper-Kravitz, M., Nagler, A., Lahav, M., Peled, A., Habler, L., Ponomaryov, T., Taichman, R. S., Arenzana-Seisdedos, F., Fujii, N., et al. (2002) · Nature Immunology · doi:10.1038/ni813 · Cited by 1,332
Chondrogenic Differentiation of Cultured Human Mesenchymal Stem Cells from Marrow
Mackay, A. M., Beck, S. C., Murphy, J. M., Barry, F. P., Chichester, C. O., & Pittenger, M. F. (1998) · Tissue Engineering · doi:10.1089/ten.1998.4.415 · Cited by 1,301
Liechty, K. W., MacKenzie, T. C., Shaaban, A. F., Radu, A., Moseley, A. B., Deans, R., Marshak, D. R., & Flake, A. W. (2000) · Nature Medicine · doi:10.1038/81395 · Cited by 1,215
Barbash, I. M., Chouraqui, P., Baron, J., Feinberg, M. S., Etzion, S., Tessone, A., Miller, L., Guetta, E., Zipori, D., Kedes, L. H., et al. (2003) · Circulation · doi:10.1161/01.cir.0000084828.50310.6a · Cited by 1,197
Yamaguchi, J.-I., Kusano, K. F., Masuo, O., Kawamoto, A., Silver, M., Murasawa, S., Bosch-Marce, M., Masuda, H., Losordo, D. W., Isner, J. M., et al. (2003) · Circulation · doi:10.1161/01.cir.0000055313.77510.22 · Cited by 1,149
Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5‐azacytidine
Wakitani, S., Saito, T., & Caplan, A. I. (1995) · Muscle & Nerve · doi:10.1002/mus.880181212 · Cited by 1,076
Beyth, S., Borovsky, Z., Mevorach, D., Liebergall, M., Gazit, Z., Aslan, H., Galun, E., & Rachmilewitz, J. (2005) · Blood · doi:10.1182/blood-2004-07-2921 · Cited by 1,034
Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow
Colter, D. C., Class, R., DiGirolamo, C. M., & Prockop, D. J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.070034097 · Cited by 1,019
Sørensen, T. L., Tani, M., Jensen, J., Pierce, V., Lucchinetti, C., Folcik, V. A., Qin, S., Rottman, J., Sellebjerg, F., Strieter, R. M., et al. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5150 · Cited by 1,002
Peister, A., Mellad, J. A., Larson, B. L., Hall, B. M., Gibson, L. F., & Prockop, D. J. (2004) · Blood · doi:10.1182/blood-2003-09-3070 · Cited by 994
Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery
Hofstetter, C. P., Schwarz, E. J., Hess, D., Widenfalk, J., El Manira, A., Prockop, D. J., & Olson, L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.042678299 · Cited by 967
The Dynamic in vivo Distribution of Bone Marrow-Derived Mesenchymal Stem Cells after Infusion
Gao, J., Dennis, J. E., Muzic, R. F., Lundberg, M., & Caplan, A. I. (2001) · Cells Tissues Organs · doi:10.1159/000047856 · Cited by 951
Ponte, A. L., Marais, E., Gallay, N., Langonné, A., Delorme, B., Hérault, O., Charbord, P., & Domenech, J. (2007) · STEM CELLS · doi:10.1634/stemcells.2007-0054 · Cited by 947
(2002) · PubMed · Cited by 903
Minguell, J. J., Erices, A., & Conget, P. (2001) · Experimental Biology and Medicine · doi:10.1177/153537020122600603 · Cited by 871
Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny
Castro-Malaspina, H., Gay, R., Resnick, G., Kapoor, N., Meyers, P., Chiarieri, D., McKenzie, S., Broxmeyer, H., & Moore, M. (1980) · Blood · doi:10.1182/blood.v56.2.289.289 · Cited by 852
The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
Campbell, J. J., Haraldsen, G., Pan, J., Rottman, J., Qin, S., Ponath, P., Andrew, D. P., Warnke, R., Ruffing, N., Kassam, N., et al. (1999) · Nature · doi:10.1038/23495 · Cited by 841
Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation
in `t Anker, P. S., Scherjon, S. A., Kleijburg-van der Keur, C., Noort, W. A., Claas, F. H. J., Willemze, R., Fibbe, W. E., & Kanhai, H. H. H. (2003) · Blood · doi:10.1182/blood-2003-04-1291 · Cited by 807
Lazarus, H. M., Koc, O. N., Devine, S. M., Curtin, P., Maziarz, R. T., Holland, H. K., Shpall, E. J., McCarthy, P., Atkinson, K., Cooper, B. W., et al. (2005) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2005.02.001 · Cited by 803
Abbott, J. D., Huang, Y., Liu, D., Hickey, R., Krause, D. S., & Giordano, F. J. (2004) · Circulation · doi:10.1161/01.cir.0000147780.30124.cf · Cited by 783
Wynn, R. F., Hart, C. A., Corradi-Perini, C., O'Neill, L., Evans, C. A., Wraith, J. E., Fairbairn, L. J., & Bellantuono, I. (2004) · Blood · doi:10.1182/blood-2004-02-0526 · Cited by 773
Lévesque, J.-P., Hendy, J., Takamatsu, Y., Simmons, P. J., & Bendall, L. J. (2003) · Journal of Clinical Investigation · doi:10.1172/jci15994 · Cited by 761
Mesenchymal precursor cells in the blood of normal individuals
Zvaifler, N. J., Marinova-Mutafchieva, L., Adams, G., Edwards, C. J., Moss, J., Burger, J. A., & Maini, R. N. (2000) · Arthritis Research & Therapy · doi:10.1186/ar130 · Cited by 750
Transcytosis and Surface Presentation of IL-8 by Venular Endothelial Cells
Middleton, J., Neil, S., Wintle, J., Clark-Lewis, I., Moore, H., Lam, C., Auer, M., Hub, E., & Rot, A. (1997) · Cell · doi:10.1016/s0092-8674(00)80422-5 · Cited by 729
Self-citationHonczarenko, M., Le, Y., Swierkowski, M., Ghiran, I., Glodek, A. M., & Silberstein, L. E. (2006) · Stem Cells · doi:10.1634/stemcells.2005-0319 · Cited by 722
Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells
Conget, P. A., & Minguell, J. J. (1999) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199910)181:1<67::aid-jcp7>3.0.co;2-c · Cited by 711
Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1
Doitsidou, M., Reichman-Fried, M., Stebler, J., Köprunner, M., Dörries, J., Meyer, D., Esguerra, C. V., Leung, T., & Raz, E. (2002) · Cell · doi:10.1016/s0092-8674(02)01135-2 · Cited by 697
Chemokines in pathology and medicine
Baggiolini, M. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00867.x · Cited by 677
Lymphotactin: a Cytokine that Represents a New Class of Chemokine
Kelner, G. S., Kennedy, J., Bacon, K. B., Kleyensteuber, S., Largaespada, D. A., Jenkins, N. A., Copeland, N. G., Bazan, J. F., Moore, K. W., Schall, T. J., et al. (1994) · Science · doi:10.1126/science.7973732 · Cited by 648
Haynesworth, S. E., Barer, M. A., & Caplan, A. I. (1992) · Bone · doi:10.1016/8756-3282(92)90363-2 · Cited by 643
Kunkel, E. J., Campbell, J. J., Haraldsen, G., Pan, J., Boisvert, J., Roberts, A. I., Ebert, E. C., Vierra, M. A., Goodman, S. B., Genovese, M. C., et al. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.5.761 · Cited by 638
Leukocyte polarization in cell migration and immune interactions
Sanchez-Madrid, F. (1999) · The EMBO Journal · doi:10.1093/emboj/18.3.501 · Cited by 616
Freyman, T., Polin, G., Osman, H., Crary, J., Lu, M., Cheng, L., Palasis, M., & Wilensky, R. L. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehi818 · Cited by 613
Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells
Jones, E. A., Kinsey, S. E., English, A., Jones, R. A., Straszynski, L., Meredith, D. M., Markham, A. F., Jack, A., Emery, P., & McGonagle, D. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10696 · Cited by 612
Sordi, V., Malosio, M. L., Marchesi, F., Mercalli, A., Melzi, R., Giordano, T., Belmonte, N., Ferrari, G., Leone, B. E., Bertuzzi, F., et al. (2005) · Blood · doi:10.1182/blood-2004-09-3507 · Cited by 602
Formation of Bone and Cartilage by Marrow Stromal Cells in Diffusion Chambers in Vivo
ASHTON, B. A., ALLEN, T. D., HOWLETT, C. R., EAGLESOM, C. C., HATTORI, A., & OWEN, M. (1980) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-198009000-00040 · Cited by 600
Self-citationKawada, H., Fujita, J., Kinjo, K., Matsuzaki, Y., Tsuma, M., Miyatake, H., Muguruma, Y., Tsuboi, K., Itabashi, Y., Ikeda, Y., et al. (2004) · Blood · doi:10.1182/blood-2004-04-1488 · Cited by 566
Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells
Rüster, B., Göttig, S., Ludwig, R. J., Bistrian, R., Müller, S., Seifried, E., Gille, J., & Henschler, R. (2006) · Blood · doi:10.1182/blood-2006-05-025098 · Cited by 562
Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI
Arbab, A. S., Yocum, G. T., Kalish, H., Jordan, E. K., Anderson, S. A., Khakoo, A. Y., Read, E. J., & Frank, J. A. (2004) · Blood · doi:10.1182/blood-2004-02-0655 · Cited by 529
Mesenchymal stem cells: paradoxes of passaging
Javazon, E. H., Beggs, K. J., & Flake, A. W. (2004) · Experimental Hematology · doi:10.1016/j.exphem.2004.02.004 · Cited by 527
Nagaya, N., Fujii, T., Iwase, T., Ohgushi, H., Itoh, T., Uematsu, M., Yamagishi, M., Mori, H., Kangawa, K., & Kitamura, S. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01071.2003 · Cited by 519
Anker, P. S. I. `., Noort, W. A., Scherjon, S. A., der Keur, C. K., Kruisselbrink, A. B., van Bezooijen, R. L., Beekhuizen, W., Willemze, R., Kanhai, H. H. H., & Fibbe, W. E. (2003) · PubMed · Cited by 518
Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection
Baddoo, M., Hill, K., Wilkinson, R., Gaupp, D., Hughes, C., Kopen, G. C., & Phinney, D. G. (2003) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10594 · Cited by 494
Zabel, B. A., Agace, W. W., Campbell, J. J., Heath, H. M., Parent, D., Roberts, A. I., Ebert, E. C., Kassam, N., Qin, S., Zovko, M., et al. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.9.1241 · Cited by 488
Mahmood, A., Lu, D., Lu, M., & Chopp, M. (2003) · Neurosurgery · doi:10.1227/01.neu.0000079333.61863.aa · Cited by 478
Le Blanc, K., & Ringdén, O. (2005) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2005.01.005 · Cited by 471
Frid, M. G., Brunetti, J. A., Burke, D. L., Carpenter, T. C., Davie, N. J., Reeves, J. T., Roedersheimer, M. T., van Rooijen, N., & Stenmark, K. R. (2006) · The American Journal of Pathology · doi:10.2353/ajpath.2006.050599 · Cited by 449
D’Ambrosio, D., Iellem, A., Bonecchi, R., Mazzeo, D., Sozzani, S., Mantovani, A., & Sinigaglia, F. (1998) · PubMed · Cited by 438
Cyrne, L., Guerreiro, P., Cardoso, A. C., Rodrigues-Pousada, C., & Soares, H. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00240-2 · Cited by 433
Devine, S. M., Bartholomew, A. M., Mahmud, N., Nelson, M., Patil, S., Hardy, W., Sturgeon, C., Hewett, T., Chung, T., Stock, W., et al. (2001) · Experimental Hematology · doi:10.1016/s0301-472x(00)00635-4 · Cited by 430
Millán, J., Hewlett, L., Glyn, M., Toomre, D., Clark, P., & Ridley, A. J. (2006) · Nature Cell Biology · doi:10.1038/ncb1356 · Cited by 414
François, S., Bensidhoum, M., Mouiseddine, M., Mazurier, C., Allenet, B., Semont, A., Frick, J., Saché, A., Bouchet, S., Thierry, D., et al. (2006) · Stem Cells · doi:10.1634/stemcells.2005-0260 · Cited by 382
Hanada, K., Dennis, J. E., & Caplan, A. I. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.10.1606 · Cited by 377
D’Ambrosio, D., Iellem, A., Bonecchi, R., Mazzeo, D., Sozzani, S., Mantovani, A., & Sinigaglia, F. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.10.5111 · Cited by 372
Ringe, J., Strassburg, S., Neumann, K., Endres, M., Notter, M., Burmester, G., Kaps, C., & Sittinger, M. (2007) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21172 · Cited by 371
Kortesidis, A. (2005) · Blood · doi:10.1182/blood-2004-11-4349 · Cited by 363
Galmiche, M., Koteliansky, V., Briere, J., Herve, P., & Charbord, P. (1993) · Blood · doi:10.1182/blood.v82.1.66.bloodjournal82166 · Cited by 362
Gronthos, S., Simmons, P. J., Graves, S. E., & G. Robey, P. (2001) · Bone · doi:10.1016/s8756-3282(00)00424-5 · Cited by 356
Djouad, F., Fritz, V., Apparailly, F., Louis‐Plence, P., Bony, C., Sany, J., Jorgensen, C., & Noël, D. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21012 · Cited by 352
Homey, B., Wang, W., Soto, H., Buchanan, M. E., Wiesenborn, A., Catron, D., Müller, A., McClanahan, T. K., Dieu-Nosjean, M.-C., Orozco, R., et al. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.7.3465 · Cited by 332
Mesenchymal stem cells for bone, cartilage, tendon and skeletal muscle repair
Krampera, M., Pizzolo, G., Aprili, G., & Franchini, M. (2006) · Bone · doi:10.1016/j.bone.2006.04.020 · Cited by 321
Multipotential Mesenchymal Stem Cells Are Mobilized into Peripheral Blood by Hypoxia
Rochefort, G. Y., Delorme, B., Lopez, A., Hérault, O., Bonnet, P., Charbord, P., Eder, V., & Domenech, J. (2006) · STEM CELLS · doi:10.1634/stemcells.2006-0164 · Cited by 315
Kohyama, J., Abe, H., Shimazaki, T., Koizumi, A., Nakashima, K., Gojo, S., Taga, T., Okano, H., Hata, J.-I., & Umezawa, A. (2001) · Differentiation · doi:10.1046/j.1432-0436.2001.680411.x · Cited by 295
Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues
Ebert, L. M., Schaerli, P., & Moser, B. (2005) · Molecular Immunology · doi:10.1016/j.molimm.2004.06.040 · Cited by 294
Identification of a Novel Chemokine (CCL28), which Binds CCR10 (GPR2)
Wang, W., Soto, H., Oldham, E. R., Buchanan, M. E., Homey, B., Catron, D., Jenkins, N., Copeland, N. G., Gilbert, D. J., Nguyen, N., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001461200 · Cited by 293
Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils
Gerber, B. O., Zanni, M. P., Uguccioni, M., Loetscher, M., Mackay, C. R., Pichler, W. J., Yawalkar, N., Baggiolini, M., & Moser, B. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00371-x · Cited by 279
Bruder, S. P., Ricalton, N. S., Boynton, R. E., Connolly, T. J., Jaiswal, N., Zaia, J., & Barry, F. P. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.4.655 · Cited by 271
Osteogenesis versus chondrogenesis by BMP-2 and BMP-7 in adipose stem cells
Knippenberg, M., Helder, M. N., Zandieh Doulabi, B., Wuisman, P. I. J. M., & Klein-Nulend, J. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.052 · Cited by 263
In vivo cardiovasculogenesis by direct injection of isolated adult mesenchymal stem cells
Gojo, S. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(03)00132-0 · Cited by 255
Immunologic properties of human fetal mesenchymal stem cells
Götherström, C., Ringdén, O., Tammik, C., Zetterberg, E., Westgren, M., & Le Blanc, K. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2003.07.022 · Cited by 245
Matsumoto, R., Omura, T., Yoshiyama, M., Hayashi, T., Inamoto, S., Koh, K.-R., Ohta, K., Izumi, Y., Nakamura, Y., Akioka, K., et al. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000165696.25680.ce · Cited by 224
Horita, Y., Honmou, O., Harada, K., Houkin, K., Hamada, H., & Kocsis, J. D. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.21056 · Cited by 216
In vitro differentiation of bone and hypertrophic cartilage from periosteal-derived cells*1
NAKAHARA, H. (1991) · Experimental Cell Research · doi:10.1016/0014-4827(91)90401-f · Cited by 216
Mesenchymal stem cell adhesion to cardiac microvascular endothelium: activators and mechanisms
Segers, V. F. M., Van Riet, I., Andries, L. J., Lemmens, K., Demolder, M. J., De Becker, A. J. M. L., Kockx, M. M., & De Keulenaer, G. W. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00523.2005 · Cited by 204
Lüttichau, I. V., Notohamiprodjo, M., Wechselberger, A., Peters, C., Henger, A., Seliger, C., Djafarzadeh, R., Huss, R., & Nelson, P. J. (2005) · Stem Cells and Development · doi:10.1089/scd.2005.14.329 · Cited by 202
Mansilla, E., Marı́n, G. H., Drago, H., Sturla, F., Salas, E., Gardiner, C., Bossi, S., Lamonega, R., Guzmán, A., Nuñez, A., et al. (2006) · Transplantation Proceedings · doi:10.1016/j.transproceed.2006.02.053 · Cited by 201
Price, M. J., Chou, C.-C., Frantzen, M., Miyamoto, T., Kar, S., Lee, S., Shah, P. K., Martin, B. J., Lill, M., Forrester, J. S., et al. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2005.07.036 · Cited by 195
Migration of mesenchymal stem cells to heart allografts during chronic rejection
Wu, G. D., Nolta, J. A., Jin, Y.-S., Barr, M. L., Yu, H., Starnes, V. A., & Cramer, D. V. (2003) · Transplantation · doi:10.1097/01.tp.0000048488.35010.95 · Cited by 173
BMP Responsiveness in Human Mesenchymal Stem Cells
Diefenderfer, D. L., Osyczka, A. M., Reilly, G. C., & Leboy, P. S. (2003) · Connective Tissue Research · doi:10.1080/03008200390181825 · Cited by 154
Kinetics and differentiation of marrow stromal cells in diffusion chambers in vivo
Bab, I., Ashton, B. A., Gazit, D., Marx, G. S., Williamson, M. C., & Owen, M. E. (1986) · Journal of Cell Science · doi:10.1242/jcs.84.1.139 · Cited by 139
Self-citationHauger, O., Frost, E. E., van Heeswijk, R. B., Deminière, C., Xue, R., Delmas, Y., Combe, C., MOONEN, C. T. W., Grenier, N., & Bulte, J. W. M. (2006) · Radiology · doi:10.1148/radiol.2381041668 · Cited by 138
Yang, J., Zhou, W., Zheng, W., Ma, Y., Lin, L., Tang, T., Liu, J., Yu, J., Zhou, X., & Hu, J. (2006) · Cardiology · doi:10.1159/000093609 · Cited by 129
Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions
Gutierrez‐Ramos, J. C., Lloyd, C. M., & Gonzalo, J. A. (1999) · Immunology Today · doi:10.1016/s0167-5699(99)01522-4 · Cited by 123
A subset of human rapidly self-renewing marrow stromal cells preferentially engraft in mice
Lee, R. H., Hsu, S. C., Munoz, J. R., Jung, J. S., Lee, N. R., Pochampally, R. R., & Prockop, D. J. (2005) · Blood · doi:10.1182/blood-2005-07-2701 · Cited by 119
Mesenchymal stem cells transmigrate over the endothelial barrier
Schmidt, A., Ladage, D., Steingen, C., Brixius, K., Schinköthe, T., Klinz, F., Schwinger, R. H. G., Mehlhorn, U., & Bloch, W. (2006) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2006.05.015 · Cited by 115
Hou, Z., Nguyen, Q., Frenkel, B., Nilsson, S. K., Milne, M. L., van Wijnen, A. J., Stein, J. L., Quesenberry, P. J., Lian, J. B., & Stein, G. S. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7294 · Cited by 112
Marinova-Mutafchieva, L., Taylor, P. C., Funa, K., Maini, R. N., & Zvaifler, N. J. (2000) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200009)43:9<2046::aid-anr16>3.0.co;2-8 · Cited by 100
Mobilisation of mesenchymal cells into blood in response to skeletal muscle injury
Ramírez, M. R., Lucía, A., Gómez‐Gallego, F., Esteve-Lanao, J., Pérez‐Martínez, A., Foster, C., Andreu, A. L., Martín, M. A., Madero, L., Arenas, J., et al. (2006) · British Journal of Sports Medicine · doi:10.1136/bjsm.2006.028639 · Cited by 62
Zhang, X. S., Linkhart, T. A., Chen, S., Peng, H., Wergedal, J. E., Guttierez, G. G., Sheng, M. H. ‐., Lau, K. ‐. W., & Baylink, D. J. (2004) · The Journal of Gene Medicine · doi:10.1002/jgm.477 · Cited by 61
Identification of cultured progenitor cells from human marrow stroma
Shur, I., Marom, R., Lokiec, F., Socher, R., & Benayahu, D. (2002) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10267 · Cited by 43
Grabovsky, V., Dwir, O., & Alon, R. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201763200 · Cited by 29
Cited by
Németh, K., Leelahavanichkul, A., Yuen, P. S. T., Mayer, B., Parmelee, A., Doi, K., Robey, P. G., Leelahavanichkul, K., Koller, B. H., Brown, J. M., et al. (2009) · Nature Medicine · doi:10.1038/nm.1905 · Cited by 2,364
Ren, G., Zhang, L., Zhao, X., Xu, G., Zhang, Y., Roberts, A. I., Zhao, R. C., & Shi, Y. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2007.11.014 · Cited by 2,101
Stewart, F. A., Akleyev, A. V., Hauer-Jensen, M., Hendry, J. H., Kleiman, N. J., MacVittie, T. J., Aleman, B. M., Edgar, A. B., Mabuchi, K., Muirhead, C. R., et al. (2012) · Annals of the ICRP · doi:10.1016/j.icrp.2012.02.001 · Cited by 1,604
Hare, J. M., Traverse, J. H., Henry, T. D., Dib, N., Strumpf, R. K., Schulman, S. P., Gerstenblith, G., DeMaria, A. N., Denktas, A. E., Gammon, R. S., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.06.055 · Cited by 1,350
Mesenchymal Stromal Cells: Current Understanding and Clinical Status
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Metadata
- Authors
- Chamberlain, G., Fox, J., Ashton, B., & Middleton, J.
- Venue
- Stem Cells
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-07-26
- Volume
- 25
- Issue
- 11
- Pages
- 2739-2749
- ISSN
- 1066-5099 (ISSN-L)
- 1549-4918
- OpenAlex
- W1965425745
- Cited by
- 2,381
- References
- 121
- FWCI
- 43.44
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
