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Sex Hormones in Acquired Immunity and Autoimmune Disease

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Copper activates HIF-1α/GPER/VEGF signalling in cancer cells

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Nuclear Alternate Estrogen Receptor GPR30 Mediates 17β-Estradiol–Induced Gene Expression and Migration in Breast Cancer–Associated Fibroblasts

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Estrogen receptor alpha and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models

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Rapid steroid hormone actions initiated at the cell surface and the receptors that mediate them with an emphasis on recent progress in fish models

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Effects of bisphenol A and triclocarban on brain-specific expression of aromatase in early zebrafish embryos

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Estrogen Receptor Signaling in Lung Cancer

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GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer

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GPER Mediates Activation of HIF1α/VEGF Signaling by Estrogens

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Exercise and the Regulation of Endocrine Hormones

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Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells

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17β-Estradiol and Agonism of G-protein-Coupled Estrogen Receptor Enhance Hippocampal Memory via Different Cell-Signaling Mechanisms

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The G Protein-coupled Receptor 30 Is Up-regulated by Hypoxia-inducible Factor-1α (HIF-1α) in Breast Cancer Cells and Cardiomyocytes

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Position paper: The membrane estrogen receptor GPER – Clues and questions

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GPCRs and cancer

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Estrogen, a female hormone involved in spermatogenesis

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GPER Function in Breast Cancer: An Overview

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Sex hormones and skeletal muscle weakness

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G Protein-coupled Estrogen Receptor Mediates the Up-regulation of Fatty Acid Synthase Induced by 17β-Estradiol in Cancer Cells and Cancer-associated Fibroblasts

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GPR30, the Non-Classical Membrane G Protein Related Estrogen Receptor, Is Overexpressed in Human Seminoma and Promotes Seminoma Cell Proliferation

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Insulin-like growth factor-I regulates GPER expression and function in cancer cells

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GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice

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The steroid hormone 20-hydroxyecdysone binds to dopamine receptor to repress lepidopteran insect feeding and promote pupation

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GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells

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MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells

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Oleuropein and hydroxytyrosol activate GPER / GPR 30‐dependent pathways leading to apoptosis of ER ‐negative SKBR 3 breast cancer cells

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Neonatal exposure to genistein adversely impacts the ontogeny of hypothalamic kisspeptin signaling pathways and ovarian development in the peripubertal female rat

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Estrogen and the aging brain: an elixir for the weary cortical network

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Beyond the Antioxidant Activity of Dietary Polyphenols in Cancer: the Modulation of Estrogen Receptors (ERs) Signaling

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New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer

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Detection of an estrogen derivative in two breast cancer cell lines using a single core multimodal probe for imaging (SCoMPI) imaged by a panel of luminescent and vibrational techniques

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GPR30 Regulates Glutamate Transporter GLT-1 Expression in Rat Primary Astrocytes

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Effects of Atrazine on Estrogen Receptor α – and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts

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Cross-talk between GPER and growth factor signaling

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Come Fly with Me: An overview of dopamine receptors in Drosophila melanogaster

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SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer

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<scp>G</scp>‐Protein Oestrogen Receptor 1: Trials and Tribulations of a Membrane Oestrogen Receptor

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Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish

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Hypoxia: The force of endometriosis

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Emerging roles for the novel estrogen-sensing receptor GPER1 in the CNS

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Enhanced Antitumor Efficacy and Reduced Toxicity of Docetaxel Loaded Estradiol Functionalized Stealth Polymeric Nanoparticles

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Sex Steroid Receptors in Male Human Bladder: Expression and Biological Function

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GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response

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Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells

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Bisphenol A and Related Alkylphenols Exert Nongenomic Estrogenic Actions Through a G Protein-Coupled Estrogen Receptor 1 (Gper)/Epidermal Growth Factor Receptor (Egfr) Pathway to Inhibit Meiotic Maturation of Zebrafish Oocytes1

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Estrogen Signaling as a Therapeutic Target in Neurodevelopmental Disorders

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Pioglitazone rapidly reduces neuropathic pain through astrocyte and nongenomic PPARγ mechanisms

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Idiopathic scoliosis

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GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells

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Estradiol modulates myosin regulatory light chain phosphorylation and contractility in skeletal muscle of female mice

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Gper and ESRs are expressed in rat round spermatids and mediate oestrogen‐dependent rapid pathways modulating expression of cyclin B1 and Bax

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The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs)

Pupo, M., Vivacqua, A., Perrotta, I. D., Pisano, A., Aquila, S., Abonante, S., Gasperi‐Campani, A., Pezzi, V., & Maggiolini, M. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.05.023 · Cited by 69 · see citing works

Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes

Rago, V., Romeo, F., Giordano, F., Maggiolini, M., & Carpino, A. (2011) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-9-135 · Cited by 68 · see citing works

Intra-Testicular Signals Regulate Germ Cell Progression and Production of Qualitatively Mature Spermatozoa in Vertebrates

Meccariello, R., Chianese, R., Chioccarelli, T., Ciaramella, V., Fasano, S., Pierantoni, R., & Cobellis, G. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00069 · Cited by 69 · see citing works

Baicalein suppresses 17-β-estradiol-induced migration, adhesion and invasion of breast cancer cells via the G protein-coupled receptor 30 signaling pathway

SHANG, D., Li, Z., Zhu-xia, Z., Chen, H., Zhao, L., Wang, X., & Chen, Y. (2015) · Oncology Reports · doi:10.3892/or.2015.3786 · Cited by 67 · see citing works

Endocrine disrupting chemicals promote the growth of ovarian cancer cells via the ER‐CXCL12‐CXCR4 signaling axis

Hall, J. M., & Korach, K. S. (2012) · Molecular Carcinogenesis · doi:10.1002/mc.21913 · Cited by 67 · see citing works

Estrogen Facilitates Spinal Cord Synaptic Transmission via Membrane-bound Estrogen Receptors

Zhang, Y., Xiao, X., Zhang, X.-M., Zhao, Z.-Q., & Zhang, Y.-Q. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.368142 · Cited by 62 · see citing works

Deciphering the selective androgen receptor modulators paradigm

Zhang, X., & Sui, Z. (2012) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2013.741582 · Cited by 64 · see citing works

GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs)

Pupo, M., Pisano, A., Abonante, S., Maggiolini, M., & Musti, A. M. (2013) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2013.11.011 · Cited by 64 · see citing works

Neuronal Control of Breathing: Sex and Stress Hormones

Behan, M., & Kinkead, R. (2011) · Comprehensive physiology · doi:10.1002/cphy.c100027 · Cited by 74 · see citing works

G Protein-Coupled Estrogen Receptor Mediates Cell Proliferation through the cAMP/PKA/CREB Pathway in Murine Bone Marrow Mesenchymal Stem Cells

Chuang, S., Chen, C., Chou, Y., Ho, M., & Chang, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186490 · Cited by 63 · see citing works

Pregnancy Augments G Protein Estrogen Receptor (GPER) Induced Vasodilation in Rat Uterine Arteries via the Nitric Oxide - cGMP Signaling Pathway

Tropea, T., Francesco, E. M. D., Rigiracciolo, D. C., Maggiolini, M., Wareing, M., Osol, G., & Mandalà, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141997 · Cited by 62 · see citing works

Pathological functions of hypoxia in endometriosis

Hsiao, K.-Y. (2015) · Frontiers in Bioscience · doi:10.2741/e736 · Cited by 61 · see citing works

17β-estradiol inhibits the production of infectious particles of hepatitis C virus

Hayashida, K., Shoji, I., Deng, L., Jiang, D., Ide, Y.-H., & Hotta, H. (2010) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2010.00268.x · Cited by 61 · see citing works

Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome

Krakstad, C., Trovik, J., Wik, E., Engelsen, I. B., Werner, H. M. J., Birkeland, E. E., Raeder, M. B., Oyan, A. M., Stefansson, I. M., Kalland, K. H., et al. (2012) · British Journal of Cancer · doi:10.1038/bjc.2012.91 · Cited by 61 · see citing works

Estrogen receptor (ER) expression and function in the pregnant human myometrium: estradiol via ERα activates ERK1/2 signaling in term myometrium

Welsh, T. N., Johnson, M. D., Yi, L., Tan, H., Rahman, R., Merlino, A. A., Zakár, T., & Mesiano, S. A. (2011) · Journal of Endocrinology · doi:10.1530/joe-11-0358 · Cited by 61 · see citing works

G protein-coupled receptors function as cell membrane receptors for the steroid hormone 20-hydroxyecdysone

Zhao, X.-F. (2020) · Cell Communication and Signaling · doi:10.1186/s12964-020-00620-y · Cited by 60 · see citing works

GPR30: A G protein-coupled receptor for estrogen

Prossnitz, E. R., Arterburn, J. B., & Sklar, L. A. (2007) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.12.010 · Cited by 310 · see citing works

The ins and outs of GPR30: A transmembrane estrogen receptor

Prossnitz, E. R., Oprea, T. I., Sklar, L. A., & Arterburn, J. B. (2008) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2008.03.006 · Cited by 149 · see citing works

Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?

Luo, J., & Liu, D. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00148 · Cited by 147 · see citing works

Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30

Prossnitz, E. R., Arterburn, J. B., Smith, H. O., Oprea, T. I., Sklar, L. A., & Hathaway, H. J. (2008) · Annual Review of Physiology · doi:10.1146/annurev.physiol.70.113006.100518 · Cited by 590 · see citing works

Position paper: The membrane estrogen receptor GPER – Clues and questions

Barton, M. (2012) · Steroids · doi:10.1016/j.steroids.2012.04.001 · Cited by 112 · see citing works