Prevalence of HIV, hepatitis B, and hepatitis C in people with severe mental illness

Stanley D. Rosenberg; L. A. Goodman; Fred C. Osher; Marvin S. Swartz; Susan M. Essock; Marian I. Butterfield; Niel T. Constantine; George Wolford; Michelle P. Salyers

doi:10.2105/ajph.91.1.31

Cited by 589Hepatitis C virus researchHIV, Drug Use, Sexual RiskHIV/AIDS Research and Interventions

Prevalence of HIV, hepatitis B, and hepatitis C in people with severe mental illness

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Stanley D. Rosenberg, L. A. Goodman, Fred C. Osher, Marvin S. Swartz, Susan M. Essock, Marian I. Butterfield, Niel T. Constantine, George Wolford +1 more·2001·American Journal of Public Health

DOI 10.2105/ajph.91.1.31PMC PMC1446494

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Abstract

OBJECTIVES: This study assessed seroprevalence rates of HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) among individuals with severe mental illness. METHODS: Participants (n = 931) were patients undergoing inpatient or outpatient treatment in Connecticut, Maryland, New Hampshire, or North Carolina. RESULTS: The prevalence of HIV infection in this sample (3.1%) was approximately 8 times the estimated US population rate but lower than rates reported in previous studies of people with severe mental illness. Prevalence rates of HBV (23.4%) and HCV (19.6%) were approximately 5 and 11 times the overall estimated population rates for these infections, respectively. CONCLUSIONS: Elevated rates of HIV, HBV, and HCV were found. Of particular concern are the high rates of HCV infection, which are frequently undetected. Individuals with HCV infection commonly fail to receive appropriate treatment to limit liver damage and unknowingly may be a source of infection to others.

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Authors: Rosenberg, S. D., Goodman, L. A., Osher, F. C., Swartz, M. S., Essock, S. M., Butterfield, M. I., Constantine, N. T., Wolford, G., & Salyers, M. P.
Affiliations: Dartmouth Psychiatric Research Center (US)
ORCID: Marvin S. Swartz
Michelle P. Salyers
Venue: American Journal of Public Health
Publisher: American Public Health Association
Published: 2001-01-01
Volume: 91
Issue: 1
Pages: 31-37
ISSN: 0090-0036 (ISSN-L)
1541-0048
DOI: 10.2105/ajph.91.1.31
PMC: PMC1446494
OpenAlex: W1454421715
Cited by: 589
References: 35
Citations by year: 2025: 2 · 2024: 4 · 2023: 9 · 2022: 16 · 2021: 14 · 2020: 11 · 2019: 9 · 2018: 16 · 2017: 56 · 2016: 24 · 2015: 23 · 2014: 25 · 2013: 26 · 2012: 36
FWCI: 19.38
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: American Journal of Public Health (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01mh048103-08, 5r01mh050094-03)
National Institute of Mental Health (P50MH043703, P50-MH43703, R01-MH-50094-03S2, R01-MH48103-05)
Topics: Health Sciences › Medicine › Hepatology › Hepatitis C virus research
Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Keywords: HIV, hepatitis B, hepatitis C, severe mental illness, seroprevalence, viral hepatitis, psychiatric patients, undiagnosed infection, liver injury, infection transmission
MeSH terms: Adolescent, Adult, Mental Disorders, Female, Hepatitis B, Hepatitis C, Humans, Male, Middle Aged, Risk Factors, Sexual Behavior, United States, HIV Infections, Comorbidity, Odds Ratio, Seroepidemiologic Studies, Substance-Related Disorders

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Prevalence of HIV, hepatitis B, and hepatitis C in people with severe mental illness

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