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Cited by 300

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Fusobacterium nucleatum in Periodontal Health and Disease

Open access
·2011·Current Issues in Molecular Biology

Abstract

The pathogenesis of periodontitis involves the interplay of microbiota present in the subgingival plaque and the host responses. Inflammation and destruction of periodontal tissues are considered to result from the response of a susceptible host to a microbial biofilm containing gram-negative pathogens. Antimicrobial peptides are important contributors to maintaining the balance between health and disease in this complex environment. These include several salivary antimicrobial peptides such as β-defensins expressed in the epithelium and LL-37 expressed in both epithelium and neutrophils. Among gram-negative bacteria implicated in periodontal diseases, Fusobacterium nucleatum, is one of the most interesting. This review will focus on expression, function, regulation and functional efficacy of antimicrobial peptides against F. nucleatum. We are looking for how the presence of F. nucleatum induces secretion of peptides which have an impact on host cells and modulate immune response.

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Crossref · 10.21775/cimb.013.025

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Metadata

Venue
Current Issues in Molecular Biology
Publisher
MDPI AG
Published
2011
Volume
13
Issue
2
Pages
25-36
ISSN
1467-3037 (ISSN-L)
OpenAlex
W1419539209
Cited by
300
References
9
FWCI
15.62
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Fusobacterium nucleatum in Periodontal Health and Disease. https://app.cochat.ai/papers/10.21775/cimb.013.025
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Fusobacterium nucleatum in Periodontal Health and Disease. (2011). Current Issues in Molecular Biology. https://doi.org/10.21775/cimb.013.025

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.