Communication among Oral Bacteria

Kolenbrander, Paul E.; Andersen, Roxanna N.; Blehert, David S.; Egland, Paul G.; Foster, Jamie S.; Palmer, Robert J.

doi:10.1128/mmbr.66.3.486-505.2002

Cited by 1,022Bacterial biofilms and quorum sensingOral microbiology and periodontitis researchBacterial Genetics and Biotechnology

Communication among Oral Bacteria

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Kolenbrander, Paul E., Andersen, Roxanna N., Blehert, David S., Egland, Paul G., Foster, Jamie S., Palmer, Robert J.·2002·Microbiology and Molecular Biology Reviews

DOI 10.1128/mmbr.66.3.486-505.2002PMC PMC120797

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Abstract

SUMMARY: Human oral bacteria interact with their environment by attaching to surfaces and establishing mixed-species communities. As each bacterial cell attaches, it forms a new surface to which other cells can adhere. Adherence and community development are spatiotemporal; such order requires communication. The discovery of soluble signals, such as autoinducer-2, that may be exchanged within multispecies communities to convey information between organisms has emerged as a new research direction. Direct-contact signals, such as adhesins and receptors, that elicit changes in gene expression after cell-cell contact and biofilm growth are also an active research area. Considering that the majority of oral bacteria are organized in dense three-dimensional biofilms on teeth, confocal microscopy and fluorescently labeled probes provide valuable approaches for investigating the architecture of these organized communities in situ. Oral biofilms are readily accessible to microbiologists and are excellent model systems for studies of microbial communication. One attractive model system is a saliva-coated flowcell with oral bacterial biofilms growing on saliva as the sole nutrient source; an intergeneric mutualism is discussed. Several oral bacterial species are amenable to genetic manipulation for molecular characterization of communication both among bacteria and between bacteria and the host. A successful search for genes critical for mixed-species community organization will be accomplished only when it is conducted with mixed-species communities.

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Fusobacterium nucleatum usually resides in the middle of dental biofilms where it bridges early and late colonizers.
“Fusobacterium nucleatum, a spindle-shaped bacterium with multi-species coaggregation interactions [20,21] that usually resides in the middle of dental biofilms where it bridges early and late colonizers [22]”
From Coaggregation of oral pathogens by postbiotic lactobacilli (2025) · cites this paper as [20]
The ‘F. nucleatum and Late Colonizers’ section explicitly says that F. nucleatum bridges early and late colonizers. The ‘In Vivo’ section reports preferential colonization of the middle and deep zones of unattached subgingival plaque, but does not establish that it usually resides in the middle of dental biofilms generally. (LLM, conf=0.85)
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Phylogenetic identification and in situ detection of individual microbial cells without cultivation
Amann, R., Ludwig, W., & Schleifer, K. (1995) · Microbiological reviews · doi:10.1128/mr.59.1.143-169.1995 · Cited by 9,508 · see citing works
Quorum Sensing in Bacteria
Miller, M. B., & Bassler, B. L. (2001) · Annual Review of Microbiology · doi:10.1146/annurev.micro.55.1.165 · Cited by 5,127 · see citing works
Microbial complexes in subgingival plaque
Socransky, S. S., Haffajee, A. D., Cugini, M. A., Smith, C., & Kent, R. L. (1998) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1998.tb02419.x · Cited by 5,050 · see citing works
Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations
Amann, R., Binder, B. J., Olson, R. J., Chisholm, S. W., Devereux, R., & Stahl, D. A. (1990) · Applied and Environmental Microbiology · doi:10.1128/aem.56.6.1919-1925.1990 · Cited by 3,998 · see citing works
Bacterial Biofilms in Nature and Disease
Costerton, J. W., Cheng, K. J., Geesey, G. G., Ladd, T. I., Nickel, J. C., Dasgupta, M., & Marrie, T. J. (1987) · Annual Review of Microbiology · doi:10.1146/annurev.mi.41.100187.002251 · Cited by 3,145 · see citing works
Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators
Fuqua, W. C., Winans, S. C., & Greenberg, E. P. (1994) · Journal of Bacteriology · doi:10.1128/jb.176.2.269-275.1994 · Cited by 2,941 · see citing works
A Molecular View of Microbial Diversity and the Biosphere
Pace, N. R. (1997) · Science · doi:10.1126/science.276.5313.734 · Cited by 2,735 · see citing works
Bacteriocins of gram-positive bacteria
Jack, R. W., Tagg, J. R., & Ray, B. (1995) · Microbiological Reviews · doi:10.1128/mr.59.2.171-200.1995 · Cited by 2,711 · see citing works
Extracellular DNA Required for Bacterial Biofilm Formation
Whitchurch, C. B., Tolker-Nielsen, T., Ragas, P. C., & Mattick, J. S. (2002) · Science · doi:10.1126/science.295.5559.1487 · Cited by 2,203 · see citing works
Bacterial Diversity in Human Subgingival Plaque
Paster, B. J., Boches, S. K., Galvin, J. L., Ericson, R. E., Lau, C. N., Levanos, V. A., Sahasrabudhe, A., & Dewhirst, F. E. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.12.3770-3783.2001 · Cited by 2,008 · see citing works
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences
Tatusova, T. A., & Madden, T. L. (1999) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1999.tb13575.x · Cited by 1,789 · see citing works
Genetic diversity in Sargasso Sea bacterioplankton
Giovannoni, S. J., Britschgi, T. B., Moyer, C. L., & Field, K. G. (1990) · Nature · doi:10.1038/345060a0 · Cited by 1,654 · see citing works
Structural identification of a bacterial quorum-sensing signal containing boron
Chen, X., Schauder, S., Potier, N., DORSSELAER, A. V., Pelczer, I., Bassler, B. L., & Hughson, F. M. (2002) · Nature · doi:10.1038/415545a · Cited by 1,572 · see citing works
The bacteria of periodontal diseases
Moore, W. E., & Moore, L. V. H. (1994) · Periodontology 2000 · doi:10.1111/j.1600-0757.1994.tb00019.x · Cited by 1,077 · see citing works
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule
Schauder, S., Shokat, K. M., Surette, M. G., & Bassler, B. L. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02532.x · Cited by 1,039 · see citing works
Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production
Surette, M. G., Miller, M. B., & Bassler, B. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1639 · Cited by 980 · see citing works
Oral Microbial Communities: Biofilms, Interactions, and Genetic Systems
Kolenbrander, P. E. (2000) · Annual Review of Microbiology · doi:10.1146/annurev.micro.54.1.413 · Cited by 894 · see citing works
Self-citation
Optical sectioning of microbial biofilms
Lawrence, J. R., Korber, D. R., Hoyle, B. D., Costerton, J. W., & Caldwell, D. E. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.20.6558-6567.1991 · Cited by 828 · see citing works
Fluorescence in situ hybridization (FISH) for direct visualization of microorganisms
Moter, A., & Göbel, U. B. (2000) · Journal of Microbiological Methods · doi:10.1016/s0167-7012(00)00152-4 · Cited by 786 · see citing works
Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi
Bassler, B. L., Greenberg, E. P., & Stevens, A. M. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.12.4043-4045.1997 · Cited by 757 · see citing works
Molecular Analysis of Bacterial Species Associated with Childhood Caries
Becker, M. R., Paster, B. J., Leys, E. J., Moeschberger, M. L., Kenyon, S. G., Galvin, J. L., Boches, S. K., Dewhirst, F. E., & Griffen, A. L. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.3.1001-1009.2002 · Cited by 735 · see citing works
Adhere today, here tomorrow: oral bacterial adherence
Kolenbrander, P. E., & London, J. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.11.3247-3252.1993 · Cited by 717 · see citing works
Self-citation
Multiple signalling systems controlling expression of luminescence in Vibrio harveyi : sequence and function of genes encoding a second sensory pathway
Bassler, B. L., Wright, M. E., & Silverman, M. R. (1994) · Molecular Microbiology · doi:10.1111/j.1365-2958.1994.tb00422.x · Cited by 701 · see citing works
Combination of Fluorescent In Situ Hybridization and Microautoradiography—a New Tool for Structure-Function Analyses in Microbial Ecology
Lee, N., Nielsen, P. H., Andreasen, K., et al. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.3.1289-1297.1999 · Cited by 657 · see citing works
Bacterial diversity within the human subgingival crevice
Kroes, I., Lepp, P. W., & Relman, D. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.25.14547 · Cited by 606 · see citing works
Cell-cell signaling in bacteria
Dunny, G. M., & Winans, S. C. (1999) · ASM Press eBooks · Cited by 543 · see citing works
Natural Genetic Transformation of Streptococcus mutans Growing in Biofilms
Li, Y.-H., Lau, P. C. Y., Lee, J. H., Ellen, R. P., & Cvitkovitch, D. G. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.3.897-908.2001 · Cited by 526 · see citing works
Streptococcus gordonii Biofilm Formation: Identification of Genes that Code for Biofilm Phenotypes
Loo, C., Corliss, D. A., & Ganeshkumar, N. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.5.1374-1382.2000 · Cited by 491 · see citing works
Microbiology of the early colonization of human enamel and root surfaces in vivo
Nyvad, B., & Kilian, M. (1987) · European Journal Of Oral Sciences · doi:10.1111/j.1600-0722.1987.tb01627.x · Cited by 484 · see citing works
A Quorum-Sensing Signaling System Essential for Genetic Competence in Streptococcus mutans Is Involved in Biofilm Formation
Li, Y.-H., Tang, N., Aspiras, M., Lau, P. C. Y., Lee, J. H., Ellen, R. P., & Cvitkovitch, D. G. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.10.2699-2708.2002 · Cited by 480 · see citing works
The languages of bacteriaPreprint
Schauder, S., & Bassler, B. L. (2001) · Genes & Development · doi:10.1101/gad.899601 · Cited by 462 · see citing works
Structure of the Cell Wall Anchor of Surface Proteins in Staphylococcus aureus
Schneewind, O., Fowler, A. V., & Faull, K. F. (1995) · Science · doi:10.1126/science.7701329 · Cited by 447 · see citing works
Interactions between Periodontal Bacteria and Human Oral Epithelial Cells: Fusobacterium nucleatum Adheres to and Invades Epithelial Cells
Han, Y. W., Shi, W., Huang, G. T.-J., Kinder Haake, S., Park, N.-H., Kuramitsu, H., & Genco, R. J. (2000) · Infection and Immunity · doi:10.1128/iai.68.6.3140-3146.2000 · Cited by 435 · see citing works
MECHANISMS OF ADHESION BY ORAL BACTERIA
Whittaker, C. J., Klier, C. M., & Kolenbrander, P. E. (1996) · Annual Review of Microbiology · doi:10.1146/annurev.micro.50.1.513 · Cited by 424 · see citing works
Self-citation
Inducible Expression of Human β-Defensin 2 byFusobacterium nucleatumin Oral Epithelial Cells: Multiple Signaling Pathways and Role of Commensal Bacteria in Innate Immunity and the Epithelial Barrier
Krisanaprakornkit, S., Kimball, J. R., Weinberg, A., Darveau, R. P., Bainbridge, B. W., & Dale, B. A. (2000) · Infection and Immunity · doi:10.1128/iai.68.5.2907-2915.2000 · Cited by 419 · see citing works
Conservation of a hexapeptide sequence in the anchor region of surface proteins from Gram‐positive cocci
Fischetti, V. A., Pancholi, V., & Schneewind, O. (1990) · Molecular Microbiology · doi:10.1111/j.1365-2958.1990.tb02072.x · Cited by 411 · see citing works
Response of marine bacterioplankton to differential filtration and confinement
Ferguson, R. L., Buckley, E. N., & Palumbo, A. V. (1984) · Applied and Environmental Microbiology · doi:10.1128/aem.47.1.49-55.1984 · Cited by 399 · see citing works
The Oral Microbiota of Man From Birth to Senility
Socransky, S. S., & Manganiello, S. D. (1971) · Journal of Periodontology · doi:10.1902/jop.1971.42.8.485 · Cited by 395 · see citing works
Evidence of bacterial etiology: a historical perspective
Socransky, S. S., & Haffajee, A. D. (1994) · Periodontology 2000 · doi:10.1111/j.1600-0757.1994.tb00016.x · Cited by 375 · see citing works
DNA as a Nutrient: Novel Role for Bacterial Competence Gene Homologs
Finkel, S. E., & Kolter, R. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.21.6288-6293.2001 · Cited by 356 · see citing works
Role of Fusobacterium nucleatum and Coaggregation in Anaerobe Survival in Planktonic and Biofilm Oral Microbial Communities during Aeration
Bradshaw, D. J., Marsh, P. D., Watson, G. K., & Allison, C. (1998) · Infection and Immunity · doi:10.1128/iai.66.10.4729-4732.1998 · Cited by 351 · see citing works
The LuxS‐dependent autoinducer AI‐2 controls the expression of an ABC transporter that functions in AI‐2 uptake in Salmonella typhimurium
Taga, M. E., Semmelhack, J. L., & Bassler, B. L. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02669.x · Cited by 347 · see citing works
Genome Sequence and Analysis of the Oral Bacterium Fusobacterium nucleatum Strain ATCC 25586
Kapatral, V., Anderson, I., Ivanova, N., Reznik, G., Los, T., Lykidis, A., Bhattacharyya, A., Bartman, A. E., Gardner, W. L., Grechkin, G., et al. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.7.2005-2018.2002 · Cited by 347 · see citing works
Comparison of the Initial Streptococcal Microflora on Dental Enamel in Caries-Active and in Caries-Inactive Individuals
Nyvad, B., & Kilian, M. (2009) · Caries Research · doi:10.1159/000261281 · Cited by 337 · see citing works
Combined Microautoradiography–16S rRNA Probe Technique for Determination of Radioisotope Uptake by Specific Microbial Cell Types In Situ
Ouverney, C., & Fuhrman, J. A. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.4.1746-1752.1999 · Cited by 337 · see citing works
Depth Penetration and Detection of pH Gradients in Biofilms by Two-Photon Excitation Microscopy
Vroom, J. M., De Grauw, K. J., Gerritsen, H. C., Bradshaw, D. J., Marsh, P. D., Watson, G. K., Birmingham, J. J., & Allison, C. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.8.3502-3511.1999 · Cited by 303 · see citing works
Coaggregation of Fusobacterium nucleatum, Selenomonas flueggei, Selenomonas infelix, Selenomonas noxia, and Selenomonas sputigena with strains from 11 genera of oral bacteria
Kolenbrander, P. E., Andersen, R. N., & Moore, L. V. (1989) · Infection and Immunity · doi:10.1128/iai.57.10.3194-3203.1989 · Cited by 298 · see citing works
Self-citation
Identification of the streptococcal competence‐pheromone receptor
Håvarstein, L. S., Gaustad, P., Nes, I. F., & Morrison, D. A. (1996) · Molecular Microbiology · doi:10.1046/j.1365-2958.1996.521416.x · Cited by 289 · see citing works
Streptococcal Adhesion and Colonization
Jenkinson, H. F., & Lamont, R. J. (1997) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411970080020601 · Cited by 272 · see citing works
DNA Microarray-Based Identification of Genes Controlled by Autoinducer 2-Stimulated Quorum Sensing in Escherichia coli
DeLisa, M. P., Wu, C., Wang, L., et al. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.18.5239-5247.2001 · Cited by 267 · see citing works
The oral cavity as a reservoir of bacterial pathogens for focal infections
Gendron, R., Grenier, D., & Maheu-Robert, L.-F. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)00391-9 · Cited by 253 · see citing works
Architecture of Intact Natural Human Plaque Biofilms Studied by Confocal Laser Scanning Microscopy
Wood, S. R., Kirkham, J., Marsh, P. D., Shore, R. F., Nattress, B. R., & Robinson, C. (2000) · Journal of Dental Research · doi:10.1177/00220345000790010201 · Cited by 253 · see citing works
Structure, function and immunogenicity of streptococcal antigen I/II polypeptides
Jenkinson, H. F., & Demuth, D. R. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.2021577.x · Cited by 247 · see citing works
Mutualism versus Independence: Strategies of Mixed-Species Oral Biofilms In Vitro Using Saliva as the Sole Nutrient Source
Palmer, R. J., Jr., Kazmerzak, K. M., Hansen, M. C., & Kolenbrander, P. E. (2001) · Infection and Immunity · doi:10.1128/iai.69.9.5794-5804.2001 · Cited by 244 · see citing works
Self-citation
Intergeneric Coaggregation Among Human Oral Bacteria And Ecology Of Dental Plaque
Kolenbrander, P. E. (1988) · Annual Review of Microbiology · doi:10.1146/annurev.mi.42.100188.003211 · Cited by 244 · see citing works
Self-citation
Survival of Oral Bacteria
Bowden, G. H., & Hamilton, I. R. (1998) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411980090010401 · Cited by 241 · see citing works
Cell Density Modulates Acid Adaptation in Streptococcus mutans : Implications for Survival in Biofilms
Li, Y.-H., Hanna, M. N., Svensäter, G., Ellen, R. P., & Cvitkovitch, D. G. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.23.6875-6884.2001 · Cited by 239 · see citing works
Confocal Microscopy Study of Undisturbed and Chlorhexidine-treated Dental Biofilm
Zaura-Arite, E., van Marle, J., & ten Cate, J. M. (2001) · Journal of Dental Research · doi:10.1177/00220345010800051001 · Cited by 220 · see citing works
Assessment of GFP fluorescence in cells of Streptococcus gordonii under conditions of low pH and low oxygen concentration
Hansen, M. C., Palmer, R. J., Jr., Udsen, C., White, D. C., & Molin, S. (2001) · Microbiology · doi:10.1099/00221287-147-5-1383 · Cited by 207 · see citing works
The Group I Strain of Streptococcus mutans , UA140, Produces Both the Lantibiotic Mutacin I and a Nonlantibiotic Bacteriocin, Mutacin IV
Qi, F., Chen, P., & Caufield, P. W. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.1.15-21.2001 · Cited by 204 · see citing works
Regulation of autoinducer production in Salmonella typhimurium
Surette, M. G., & Bassler, B. L. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01199.x · Cited by 198 · see citing works
Intra- and Interspecies Regulation of Gene Expression byActinobacillus actinomycetemcomitansLuxS
Fong, K. P., Chung, W. O., Lamont, R. J., & Demuth, D. R. (2001) · Infection and Immunity · doi:10.1128/iai.69.12.7625-7634.2001 · Cited by 196 · see citing works
Periodontal Pathogens Produce Quorum Sensing Signal Molecules
Frías, J., Olle, E., & Alsina, M. (2001) · Infection and Immunity · doi:10.1128/iai.69.5.3431-3434.2001 · Cited by 194 · see citing works
Dental Caries
Gibbons, R. J., & van Houte, J. (1975) · Annual Review of Medicine · doi:10.1146/annurev.me.26.020175.001005 · Cited by 194 · see citing works
Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes
Lyon, W. R., Madden, J. C., Levin, J. C., Stein, J. L., & Caparon, M. G. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02616.x · Cited by 191 · see citing works
Mechanism of coaggregation between Actinomyces viscosus T14V and Streptococcus sanguis 34
McIntire, F. C., VATTER, A. E., Baros, J., & Arnold, J. (1978) · Infection and Immunity · doi:10.1128/iai.21.3.978-988.1978 · Cited by 183 · see citing works
Molecular characterization of a surface protein antigen gene from serotype c Streptococcus mutans, implicated in dental caries
Okahashi, N., Sasakawa, C., Yoshikawa, M., et al. (1989) · Molecular Microbiology · doi:10.1111/j.1365-2958.1989.tb00215.x · Cited by 178 · see citing works
Delineation of a segment of adsorbed salivary acidic proline-rich proteins which promotes adhesion of Streptococcus gordonii to apatitic surfaces
Gibbons, R. J., Hay, D. I., & Schlesinger, D. H. (1991) · Infection and Immunity · doi:10.1128/iai.59.9.2948-2954.1991 · Cited by 172 · see citing works
THE GENUSVEILLONELLAI
Rogosa, M. (1964) · Journal of Bacteriology · doi:10.1128/jb.87.1.162-170.1964 · Cited by 157 · see citing works
Transfer of a conjugative transposon, Tn 5397 in a model oral biofilm
Roberts, A. P., Pratten, J. R., Wilson, M., & Mullany, P. P. (1999) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1999.tb13714.x · Cited by 157 · see citing works
Chemistry of sex attraction.
Roelofs, W. L. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.1.44 · Cited by 156 · see citing works
Establishment of Streptococcus sanguis in the mouths of infants
Carlsson, J., Grahnén, H., Jonsson, G., & Wikner, S. (1970) · Archives of Oral Biology · doi:10.1016/0003-9969(70)90005-1 · Cited by 156 · see citing works
Invasion of dentinal tubules by oral streptococci is associated with collagen recognition mediated by the antigen I/II family of polypeptides
Love, R. M., McMillan, M. D., & Jenkinson, H. F. (1997) · Infection and Immunity · doi:10.1128/iai.65.12.5157-5164.1997 · Cited by 153 · see citing works
Intra- and Interspecies Signaling between Streptococcus salivarius and Streptococcus pyogenes Mediated by SalA and SalA1 Lantibiotic Peptides
Upton, M., Tagg, J. R., Wescombe, P. A., & Jenkinson, H. F. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.13.3931-3938.2001 · Cited by 153 · see citing works
LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence
Burgess, N. A., Kirke, D. F., Williams, P. M., Winzer, K., Hardie, K. R., Meyers, N. L., Aduse‐Opoku, J., Curtis, M. A., & Cámara, M. (2002) · Microbiology · doi:10.1099/00221287-148-3-763 · Cited by 153 · see citing works
Identification and Characterization of hsa , the Gene Encoding the Sialic Acid-Binding Adhesin of Streptococcus gordonii DL1
Takahashi, Y., Konishi, K., Cisar, J. O., & Yoshikawa, M. (2002) · Infection and Immunity · doi:10.1128/iai.70.3.1209-1218.2002 · Cited by 145 · see citing works
Signaling System in Porphyromonas gingivalis Based on a LuxS Protein
Chung, W. O., Park, Y., Lamont, R. J., et al. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.13.3903-3909.2001 · Cited by 144 · see citing works
Sequence analysis of the cloned streptococcal cell surface antigen I/II
Kelly, C., Evans, P., Bergmeier, L. A., Lee, S. F., Progulske‐Fox, A., Hams, A. C., Aitken, A., Bleiweis, A. S., & Lehner, T. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)81632-1 · Cited by 143 · see citing works
Tandem genes encode cell‐surface polypeptides SspA and SspB which mediate adhesion of the oral bacterium Streptococcus gordonii to human and bacterial receptors
Demuth, D. R., Duan, Y., Brooks, W., Holmes, A. R., McNab, R., & Jenkinson, H. F. (1996) · Molecular Microbiology · doi:10.1111/j.1365-2958.1996.tb02627.x · Cited by 138 · see citing works
Intrageneric coaggregation among strains of human oral bacteria: potential role in primary colonization of the tooth surface
Kolenbrander, P. E., Andersen, R. N., & Moore, L. V. H. (1990) · Applied and Environmental Microbiology · doi:10.1128/aem.56.12.3890-3894.1990 · Cited by 136 · see citing works
Self-citation
The Growth of Oral Bacteria on Saliva
Jong, M. H. D., & van der Hoeven, J. S. (1987) · Journal of Dental Research · doi:10.1177/00220345870660021901 · Cited by 136 · see citing works
Symbiosis of Streptococcus mutans and Veillonella alcalescens in mixed continuous cultures
Mikx, F. H. M., & van der Hoeven, J. S. (1975) · Archives of Oral Biology · doi:10.1016/0003-9969(75)90224-1 · Cited by 132 · see citing works
The indigenous oral flora of man—I
McCarthy, C. M., Snyder, M. L., & Parker, R. B. (1965) · Archives of Oral Biology · doi:10.1016/0003-9969(65)90058-0 · Cited by 124 · see citing works
The primary structures of six human salivary acidic proline-rich proteins (PRP-1, PRP-2, PRP-3, PRP-4, PIF-s and PIF-f)
Hay, D. I., Bennick, A., Schlesinger, D. H., Minaguchi, K., Madapallimattam, G., & Schluckebier, S. K. (1988) · Biochemical Journal · doi:10.1042/bj2550015 · Cited by 123 · see citing works
Community structure and co-operation in biofilms
Allison, D., Gilbert, P., Lappin-Scott, H. M., & Wilson, M. (2000) · ePrints Soton (University of Southampton) · Cited by 120 · see citing works
Nutritional relationships between oral bacteria
Grenier, D., & Mayrand, D. (1986) · Infection and Immunity · doi:10.1128/iai.53.3.616-620.1986 · Cited by 116 · see citing works
Fate of Free DNA and Transformation of the Oral Bacterium Streptococcus gordonii DL1 by Plasmid DNA in Human Saliva
Mercer, D. K., Scott, K. P., Bruce-Johnson, W. A., Glover, L. A., & Flint, H. J. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.1.6-10.1999 · Cited by 110 · see citing works
Mixed infection with Porphyromonas gingivalis and Fusobacterium nucleatum in a murine lesion model: potential synergistic effects on virulence
Feuille, F., Ebersole, J. L., Kesavalu, L. N., Stepfen, M. J., & Holt, S. C. (1996) · Infection and Immunity · doi:10.1128/iai.64.6.2094-2100.1996 · Cited by 109 · see citing works
Role of Streptococcus gordonii Amylase-Binding Protein A in Adhesion to Hydroxyapatite, Starch Metabolism, and Biofilm Formation
Rogers, J. D., Palmer, R. J., Jr., Kolenbrander, P. E., & Scannapieco, F. A. (2001) · Infection and Immunity · doi:10.1128/iai.69.11.7046-7056.2001 · Cited by 108 · see citing works
Self-citation
Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site
Hilgers, M. T., & Ludwig, M. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.191223098 · Cited by 107 · see citing works
Identification of oral streptococci using PCR-based, reverse-capture, checkerboard hybridization
Paster, B. J., Bartoszyk, I. M., & Dewhirst, F. E. (1998) · Methods in Cell Science · doi:10.1023/a:1009715710555 · Cited by 107 · see citing works
Enterococcal sex pheromone precursors are part of signal sequences for surface lipoproteins
Clewell, D. B., An, F. Y., Flannagan, S. E., et al. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01687.x · Cited by 105 · see citing works
The Localization of Periodontal-disease-associated Bacteria in Human Periodontal Pockets
Noiri, Y., Li, L., & Ebisu, S. (2001) · Journal of Dental Research · doi:10.1177/00220345010800101301 · Cited by 101 · see citing works
A novel technique for monitoring the development of bacterial biofilms in human periodontal pockets
Wecke, J., Kersten, T., Madela, K., Moter, A., GÃ¶bel, U. B., Friedmann, A., & Bernimoulin, J. (2000) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2000.tb09324.x · Cited by 97 · see citing works
Discrete Protein Determinant Directs the Species-Specific Adherence of Porphyromonas gingivalis to Oral Streptococci
Demuth, D. R., Irvine, D. C., Costerton, J. W., Cook, G. S., & Lamont, R. J. (2001) · Infection and Immunity · doi:10.1128/iai.69.9.5736-5741.2001 · Cited by 97 · see citing works
Early Establishment of Streptococcus salivarius in the Mouths of Infants
Carlsson, J., Grahnén, H., Jonsson, G., et al. (1970) · Journal of Dental Research · doi:10.1177/00220345700490023601 · Cited by 94 · see citing works
Coinvasion of Dentinal Tubules by Porphyromonas gingivalis and Streptococcus gordonii Depends upon Binding Specificity of Streptococcal Antigen I/II Adhesin
Love, R. M., McMillan, M. D., Park, Y., et al. (2000) · Infection and Immunity · doi:10.1128/iai.68.3.1359-1365.2000 · Cited by 93 · see citing works
Identification of oral streptococci using PCR-based, reverse-capture, checkerboard hybridization
Paster, B. J., Bartoszyk, I. M., & Dewhirst, F. E. (1998) · Springer eBooks · doi:10.1007/978-94-017-2258-2_25 · Cited by 90 · see citing works
Identification of a Streptococcus gordonii SspB domain that mediates adhesion to Porphyromonas gingivalis
Brooks, W., Demuth, D. R., Gil, S., & Lamont, R. J. (1997) · Infection and Immunity · doi:10.1128/iai.65.9.3753-3758.1997 · Cited by 88 · see citing works
Interbacterial binding among strains of pathogenic and commensal oral bacterial species
Yao, E. S., Lament, R. J., Leu, S. P., & Weinberg, A. (1996) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1996.tb00334.x · Cited by 88 · see citing works
Establishment of Defined Microbial Ecosystems in Germ-Free Rats
Mikx, F. H. M., van der Hoeven, J. S., König, K. G., et al. (2009) · Caries Research · doi:10.1159/000259801 · Cited by 87 · see citing works
Transfer of Tn 916 -Like Elements in Microcosm Dental Plaques
Roberts, A. P., Cheah, G., Ready, D. R., et al. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.10.2943-2946.2001 · Cited by 85 · see citing works
Inactivation of the gene encoding surface protein SspA in Streptococcus gordonii DL1 affects cell interactions with human salivary agglutinin and oral actinomyces
Jenkinson, H. F., Terry, S. D., McNab, R., & Tannock, G. W. (1993) · Infection and Immunity · doi:10.1128/iai.61.8.3199-3208.1993 · Cited by 84 · see citing works
Sequence and structural analysis of surface protein antigen I/II (SpaA) of Streptococcus sobrinus
LaPolla, R. J., Haron, J. A., Kelly, C. G., Taylor, W. R., Bohart, C., Hendricks, M., Pyati, J. P., Graff, R. T., Ma, J. K., & Lehner, T. (1991) · Infection and Immunity · doi:10.1128/iai.59.8.2677-2685.1991 · Cited by 84 · see citing works
Spatial Arrangements and Associative Behavior of Species in an In Vitro Oral Biofilm Model
Guggenheim, M., Shapiro, S., Gmür, R., & Guggenheim, B. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.3.1343-1350.2001 · Cited by 84 · see citing works
Lectin recognition of host-like saccharide motifs in streptococcal cell wall polysaccharides
Cisar, J. O., Sandberg, A. L., Abeygunawardana, C., Reddy, G. P., & Bush, C. A. (1995) · Glycobiology · doi:10.1093/glycob/5.7.655 · Cited by 83 · see citing works
Identification of the cAD1 Sex Pheromone Precursor in Enterococcus faecalis
An, F. Y., & Clewell, D. B. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.7.1880-1887.2002 · Cited by 80 · see citing works
A special relationship between spherical and filamentous microorganisms in mature human dental plaque
Jones, S. J. (1972) · Archives of Oral Biology · doi:10.1016/0003-9969(72)90081-7 · Cited by 79 · see citing works
Conservation of the gene encoding streptococcal antigen I/II in oral streptococci
Ma, J. K., Kelly, C. G., MUNRO, G. H., et al. (1991) · Infection and Immunity · doi:10.1128/iai.59.8.2686-2694.1991 · Cited by 79 · see citing works
A specific cell surface antigen of Streptococcus gordonii is associated with bacterial hemagglutination and adhesion to alpha2-3-linked sialic acid-containing receptors
Takahashi, Y., Sandberg, A. L., Rühl, S., Muller, J., & Cisar, J. O. (1997) · Infection and Immunity · doi:10.1128/iai.65.12.5042-5051.1997 · Cited by 78 · see citing works
Structural and antigenic types of cell wall polysaccharides from viridans group streptococci with receptors for oral actinomyces and streptococcal lectins
Cisar, J. O., Sandberg, A. L., Reddy, G. P., Abeygunawardana, C., & Bush, C. A. (1997) · Infection and Immunity · doi:10.1128/iai.65.12.5035-5041.1997 · Cited by 75 · see citing works
Attachment of Fusobacterium nucleatum PK1594 to mammalian cells and its coaggregation with periodontopathogenic bacteria are mediated by the same galactose‐binding adhesin
Weiss, E. I., Shaniztki, B., Dotan, M., Ganeshkumar, N., Kolenbrander, P. E., & Metzger, Z. (2000) · Oral Microbiology and Immunology · doi:10.1034/j.1399-302x.2000.150606.x · Cited by 73 · see citing works
Self-citation
An overview of biofilms as functional communities
WIMPENNY, J. W. T. (2000) · Cambridge University Press eBooks · doi:10.1017/cbo9780511754814.002 · Cited by 73 · see citing works
Acquisition of Plasmin Activity by Fusobacterium nucleatum subsp. nucleatum and Potential Contribution to Tissue Destruction during Periodontitis
Darenfed, H., Grenier, D., & Mayrand, D. (1999) · Infection and Immunity · doi:10.1128/iai.67.12.6439-6444.1999 · Cited by 72 · see citing works
Identification of Independent Streptococcus gordonii SspA and SspB Functions in Coaggregation with Actinomyces naeslundii
Egland, P. G., Dû, L. D., & Kolenbrander, P. E. (2001) · Infection and Immunity · doi:10.1128/iai.69.12.7512-7516.2001 · Cited by 69 · see citing works
Self-citation
Helicobacter pylori adheres selectively to Fusobacterium spp
Andersen, R. N., Ganeshkumar, N., & Kolenbrander, P. E. (1998) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1998.tb00751.x · Cited by 68 · see citing works
Self-citation
A quantitative method to study co-adhesion of microorganisms in a parallel plate flow chamber: basic principles of the analysis
Bos, R., van der Mei, H. C., Meinders, J. M., & Busscher, H. J. (1994) · Journal of Microbiological Methods · doi:10.1016/0167-7012(94)90053-1 · Cited by 67 · see citing works
Role of interbacterial adherence in colonization of the oral cavities of gnotobiotic rats infected with Streptococcus mutans and Veillonella alcalescens
McBride, B. C., & van der Hoeven, J. S. (1981) · Infection and Immunity · doi:10.1128/iai.33.2.467-472.1981 · Cited by 66 · see citing works
An immunohistochemical study on the localization of Porphyromonas gingivalis, Campylobacter rectus and Actinomyces viscosus in human periodontal pockets
Noiri, Y., Ozaki, K., Nakae, H., Matsuo, T., & Ebisu, S. (1997) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1997.tb00937.x · Cited by 66 · see citing works
Ultrastructure of the attachment device between coccal and filamentous microorganisms in “corn cob” formations of dental plaque
Listgarten, M. A., Mayo, H. E., & Amsterdam, M. (1973) · Archives of Oral Biology · doi:10.1016/0003-9969(73)90105-2 · Cited by 65 · see citing works
Host modulation of tissue destruction caused by periodontopathogens: effects on a mixed microbial infection composed ofPorphyromonas gingivalisandFusobacterium nucleatum
Ebersole, J. L., Feuille, F., Kesavalu, L. N., et al. (1997) · Microbial Pathogenesis · doi:10.1006/mpat.1996.0129 · Cited by 61 · see citing works
Identification of Saliva-Regulated Genes of Streptococcus gordonii DL1 by Differential Display Using Random Arbitrarily Primed PCR
Dû, L. D., & Kolenbrander, P. E. (2000) · Infection and Immunity · doi:10.1128/iai.68.8.4834-4837.2000 · Cited by 60 · see citing works
Self-citation
Complete nucleotide sequence of the gene for a surface protein antigen of Streptococcus sobrinus
Tokuda, M., Okahashi, N., Takahashi, I., et al. (1991) · Infection and Immunity · doi:10.1128/iai.59.9.3309-3312.1991 · Cited by 59 · see citing works
[24] Spatial organization of oral bacteria in biofilms
Kolenbrander, P. E., Andersen, R. N., Kazmerzak, K. M., Wu, R., & Palmer, R. J., Jr. (1999) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(99)10026-0 · Cited by 56 · see citing works
Self-citation
Symbiotic Relationship of Veillonella alcalescens and Streptococcus mutans in Dental Plaque in Gnotobiotic Rats
van der Hoeven, J. S., Toorop, A. I., & Mikx, F. H. M. (2009) · Caries Research · doi:10.1159/000260324 · Cited by 56 · see citing works
Sequential deglycosylation and utilization of the N-linked, complex- type glycans of human alpha1-acid glycoprotein mediates growth of Streptococcus oralis
Byers, H. (1999) · Glycobiology · doi:10.1093/glycob/9.5.469 · Cited by 56 · see citing works
Oral bacterial ecology: the molecular basis.
Kuramitsu, H. K., & Ellen, R. P. (2000) · Cited by 53 · see citing works
Transformation of an oral bacterium via chromosomal integration of free DNA in the presence of human saliva
Mercer, D. K., Scott, K. P., Melville, C. M., et al. (2001) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2001.tb10709.x · Cited by 53 · see citing works
Utilization of Sialic Acid by Viridans Streptococci
Byers, H. L., Homer, K. A., & Beighton, D. (1996) · Journal of Dental Research · doi:10.1177/00220345960750080701 · Cited by 53 · see citing works
[21] Use of constant depth film fermentor in studies of biofilms of oral bacteria
Wilson, M. (1999) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(99)10023-5 · Cited by 48 · see citing works
A flowcell for the study of plaque removal and regrowth
Palmer, R. J., Jr., & Caldwell, D. E. (1995) · Journal of Microbiological Methods · doi:10.1016/0167-7012(95)00068-2 · Cited by 47 · see citing works
Comparison of the distribution of Actinomyces in dental plaque on inserted enamel and natural tooth surfaces in periodontal health and disease
Liljemark, W. F., Bloomquist, C. G., Bandt, C. L., Pihlstrom, B. L., Hinrichs, J. E., & Wolff, L. F. (1993) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1993.tb00536.x · Cited by 46 · see citing works
Saliva-mediated aggregation of Enterococcus faecalis transformed with a Streptococcus sanguis gene encoding the SSP-5 surface antigen
Demuth, D. R., Berthold, P., Leboy, P. S., et al. (1989) · Infection and Immunity · doi:10.1128/iai.57.5.1470-1475.1989 · Cited by 45 · see citing works
[27] Retrieval of biofilms from the oral cavity
Palmer, R. J., Jr., Wu, R., Gordon, S. M., Bloomquist, C. G., Liljemark, W. F., Kilian, M., & Kolenbrander, P. E. (2001) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(01)37028-3 · Cited by 44 · see citing works
Self-citation
Expression of Green Fluorescent Protein in Streptococcus gordonii DL1 and Its Use as a Species-Specific Marker in Coadhesion with Streptococcus oralis 34 in Saliva-Conditioned Biofilms In Vitro
Aspiras, M., Kazmerzak, K. M., Kolenbrander, P. E., McNab, R., Hardegen, N. J., & Jenkinson, H. F. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.9.4074-4083.2000 · Cited by 44 · see citing works
Self-citation
Stimulation of in vitro Growth of Treponema denticola by Extracellular Growth Factors Produced by Porphyromonas gingivalis
Nilius, A. M., Spencer, S. C., & Simonson, L. G. (1993) · Journal of Dental Research · doi:10.1177/00220345930720060601 · Cited by 40 · see citing works
Streptococcal Transformation: Essential Features and Applications of a Natural Gene Exchange System
Lunsford, R. D. (1998) · Plasmid · doi:10.1006/plas.1997.1323 · Cited by 40 · see citing works
Expression and Functional Properties of the Streptococcus intermedius Surface Protein Antigen I/II
Petersen, F. C., Pasco, S., Ogier, J., Klein, J. P., ASSEV, S., & Scheie, A. A. (2001) · Infection and Immunity · doi:10.1128/iai.69.7.4647-4653.2001 · Cited by 37 · see citing works
Coaggregation and coadhesion in oral biofilms
Kolenbrander, P. E., Andersen, R. N., Kazmerzak, K. M., & Palmer, R. J., Jr. (2000) · Cambridge University Press eBooks · doi:10.1017/cbo9780511754814.006 · Cited by 36 · see citing works
Self-citation
Dominant Cross-reactive Antibodies Generated during the Response to a Variety of Oral Bacterial Species Detect Phosphorylcholine
Gmür, R., Thumheer, T., & Guggenheim, B. (1999) · Journal of Dental Research · doi:10.1177/00220345990780011201 · Cited by 36 · see citing works
Effect of saliva on coaggregation of oral Actinomyces and Streptococcus species
Kolenbrander, P. E., & Phucas, C. S. (1984) · Infection and Immunity · doi:10.1128/iai.44.2.228-233.1984 · Cited by 32 · see citing works
Self-citation
Defining antibody targets in Streptococcus oralis infection
Burnie, J., Brooks, W., Donohoe, M., et al. (1996) · Infection and Immunity · doi:10.1128/iai.64.5.1600-1608.1996 · Cited by 31 · see citing works
Prevalence of the Amylase-Binding Protein A Gene ( abpA ) in Oral Streptococci
Brown, A. E., Rogers, J. D., Haase, E. M., Zelasko, P. M., & Scannapieco, F. A. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.12.4081-4085.1999 · Cited by 30 · see citing works
Establishment of Defined Microbial Ecosystems in Germ-Free Rats
Mikx, F. H. M., van der Hoeven, J. S., Plasschaert, A. J. M., et al. (2009) · Caries Research · doi:10.1159/000260188 · Cited by 30 · see citing works
Possible Release of an ArgGlyArgProGln Pentapeptide with Innate Immunity Properties from Acidic Proline-Rich Proteins by Proteolytic Activity in Commensal Streptococcus and Actinomyces Species
Li, T., Bratt, P., Jonsson, P. A., Ryberg, M., Johansson, I., Griffiths, W. J., Bergman, T., & Strömberg, N. (2000) · Infection and Immunity · doi:10.1128/iai.68.9.5425-5429.2000 · Cited by 28 · see citing works
[22] Use of continuous flow techniques in modeling dental plaque biofilms
Bradshaw, D. J., & Marsh, P. D. (1999) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(99)10024-7 · Cited by 26 · see citing works
Adhesin receptors of human oral bacteria and modeling of putative adhesin-binding domains
Cassels, F. J., Hughes, C. V., & Nauss, J. L. (1995) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/bf01569823 · Cited by 26 · see citing works
Environmental conditions modulate the expression of the sspA and sspB genes in Streptococcus gordonii
El-Sabaeny, A., Demuth, D. R., Park, Y., & Lamont, R. J. (2000) · Microbial Pathogenesis · doi:10.1006/mpat.2000.0369 · Cited by 24 · see citing works
Cloning and DNA sequencing of the surface protein antigen I/II (PAa) of Streptococcus cricetus
Tamura, H., Kikuchi, T., Shirato, R., & Kato, H. (2001) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2001.tb10573.x · Cited by 20 · see citing works
Intergeneric rosettes: sequestered surface recognition among human periodontal bacteria
Kolenbrander, P. E., & Andersen, R. N. (1988) · Applied and Environmental Microbiology · doi:10.1128/aem.54.4.1046-1050.1988 · Cited by 19 · see citing works
Self-citation
Biosynthetic enzymes regulating ratios of sex pheromone components in female redbanded leafroller moths
Roelofs, W. L., & Jurenka, R. A. (1996) · Bioorganic & Medicinal Chemistry · doi:10.1016/0968-0896(96)00026-0 · Cited by 18 · see citing works
Bacterial interactions in periodontal diseases
Mayrand, D., & Grenier, D. (1998) · Bulletin de l Institut Pasteur · doi:10.1016/s0020-2452(98)80006-7 · Cited by 17 · see citing works
Biofilms in the New Millennium: musings from a peak in Xanadu
Costerton, J. W. (2000) · Cambridge University Press eBooks · doi:10.1017/cbo9780511754814.017 · Cited by 14 · see citing works
TNF-α release by monocytic THP-1 cells through cross-linking of the extended V-region of the oral streptococcal protein I/II
Chatenay‐Rivauday, C., Yamodo, I. H., Sciotti, M., et al. (2000) · Journal of Leukocyte Biology · doi:10.1002/jlb.67.1.81 · Cited by 14 · see citing works
Bacteriocin production and sensitivity among coaggregating and noncoaggregating oral streptococci
Tompkins, G. R., Peavey, M. A., Birchmeier, K. R., & Tagg, J. R. (1997) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1997.tb00624.x · Cited by 11 · see citing works
Regulation of Streptococcus gordonii sspB by the sspA Gene Product
El-Sabaeny, A., Demuth, D. R., & Lamont, R. J. (2001) · Infection and Immunity · doi:10.1128/iai.69.10.6520-6522.2001 · Cited by 10 · see citing works

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An ecological and evolutionary perspective on human–microbe mutualism and disease
Dethlefsen, L., McFall-Ngai, M., & Relman, D. A. (2007) · Nature · doi:10.1038/nature06245 · Cited by 1,660 · see citing works
Oral multispecies biofilm development and the key role of cell–cell distance
Kolenbrander, P. E., Palmer, R. J., Periasamy, S., & Jakubovics, N. S. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2381 · Cited by 1,309 · see citing works
Self-citation
Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology
Hajishengallis, G., & Lamont, R. J. (2012) · Molecular Oral Microbiology · doi:10.1111/j.2041-1014.2012.00663.x · Cited by 1,267 · see citing works
Dental plaque as a biofilm and a microbial community—Implications for health and disease
Marsh, P. D. (2006) · BMC Oral Health · doi:10.1186/1472-6831-6-s1-s14 · Cited by 1,094 · see citing works
Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the ‘red complex’, a prototype polybacterial pathogenic consortium in periodontitis
Holt, S. C., & Ebersole, J. L. (2005) · Periodontology 2000 · doi:10.1111/j.1600-0757.2005.00113.x · Cited by 932 · see citing works
Bacterial interactions and successions during plaque development
Kolenbrander, P. E., Palmer, R. J., Rickard, A. H., Jakubovics, N. S., Chalmers, N. I., & Diaz, P. I. (2006) · Periodontology 2000 · doi:10.1111/j.1600-0757.2006.00187.x · Cited by 791 · see citing works
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Bacterial coaggregation: an integral process in the development of multi-species biofilms
Rickard, A. H., Gilbert, P., High, N. J., Kolenbrander, P. E., & Handley, P. S. (2003) · Trends in Microbiology · doi:10.1016/s0966-842x(02)00034-3 · Cited by 765 · see citing works
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Dental Plaque as a Microbial Biofilm
Marsh, P. D. (2004) · Caries Research · doi:10.1159/000077756 · Cited by 763 · see citing works
Oral Candidiasis: A Disease of Opportunity
Vila, T., Sultan, A. S., Montelongo-Jauregui, D., & Jabra-Rizk, M. A. (2020) · Journal of Fungi · doi:10.3390/jof6010015 · Cited by 537 · see citing works
Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis
Duran-Pinedo, A. E., Chen, T., Teles, R., Starr, J. R., Wang, X., Krishnan, K., & Frias-Lopez, J. (2014) · The ISME Journal · doi:10.1038/ismej.2014.23 · Cited by 327 · see citing works
Streptococcus gordonii Modulates Candida albicans Biofilm Formation through Intergeneric Communication
Bamford, C. V., d'Mello, A., Nobbs, A. H., Dutton, L. C., Vickerman, M. M., & Jenkinson, H. F. (2009) · Infection and Immunity · doi:10.1128/iai.00438-09 · Cited by 291 · see citing works
Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans
Vanhatalo, A., Blackwell, J. R., L’Heureux, J. E., Williams, D. W., Smith, A., van der Giezen, M., Winyard, P. G., Kelly, J., & Jones, A. M. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.05.078 · Cited by 256 · see citing works
Metabolite Cross-Feeding Enhances Virulence in a Model Polymicrobial Infection
Ramsey, M. M., Rumbaugh, K. P., & Whiteley, M. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002012 · Cited by 238 · see citing works
Active invasion of Porphyromonas gingivalis and infection-induced complement activation in ApoE-/- mice brains
Poole, S., Singhrao, S. K., Chukkapalli, S., Rivera, M., Velsko, I., Kesavalu, L., & Crean, S. (2014) · Journal of Alzheimer's Disease · doi:10.3233/jad-140315 · Cited by 215 · see citing works
Interaction of Candida albicans Cell Wall Als3 Protein with Streptococcus gordonii SspB Adhesin Promotes Development of Mixed-Species Communities
Silverman, R. J., Nobbs, A. H., Vickerman, M. M., Barbour, M. E., & Jenkinson, H. F. (2010) · Infection and Immunity · doi:10.1128/iai.00685-10 · Cited by 219 · see citing works
Microbial signature profiles of periodontally healthy and diseased patients
Lourenço, T. G. B., Heller, D., Silva‐Boghossian, C. M., Cotton, S. L., Paster, B. J., & Colombo, A. P. V. (2014) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12302 · Cited by 185 · see citing works
Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stage
Velsko, I. M., Fellows Yates, J. A., Aron, F., Hagan, R. W., Frantz, L. A. F., Loe, L., Martinez, J. B. R., Chaves, E., Gosden, C., Larson, G., et al. (2019) · Microbiome · doi:10.1186/s40168-019-0717-3 · Cited by 170 · see citing works
Using DGGE profiling to develop a novel culture medium suitable for oral microbial communities: DGGE profiling for culture medium development
Tian, Y., He, X., Torralba, M., Yooseph, S., Nelson, K. E., Lux, R., McLean, J. S., Yu, G., & Shi, W. (2010) · Molecular Oral Microbiology · doi:10.1111/j.2041-1014.2010.00585.x · Cited by 133 · see citing works
Biofilm and dental implant: The microbial link
Dhir, S. (2013) · Journal of Indian Society of Periodontology · doi:10.4103/0972-124x.107466 · Cited by 129 · see citing works
The influence of oral Veillonella species on biofilms formed by Streptococcus species
Mashima, I., & Nakazawa, F. (2014) · Anaerobe · doi:10.1016/j.anaerobe.2014.05.003 · Cited by 125 · see citing works
Structure, viability and bacterial kinetics of an in vitro biofilm model using six bacteria from the subgingival microbiota: An in vitro subgingival biofilm model
Sánchez, M. C., Llama-Palacios, A., Blanc, V., León, R., Herrera, D., & Sanz, M. (2011) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2010.01341.x · Cited by 119 · see citing works
Porphyromonas gingivalis and Treponema denticola Synergistic Polymicrobial Biofilm Development
Zhu, Y., Dashper, S. G., Chen, Y.-Y., Crawford, S., Slakeski, N., & Reynolds, E. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071727 · Cited by 121 · see citing works
Mini-review: Microbial coaggregation: ubiquity and implications for biofilm development
Katharios-Lanwermeyer, S., Xi, C., Jakubovics, N. S., & Rickard, A. H. (2014) · Biofouling · doi:10.1080/08927014.2014.976206 · Cited by 104 · see citing works
Screening of probiotic candidates in human oral bacteria for the prevention of dental disease
Terai, T., Okumura, T., Imai, S., Nakao, M., Yamaji, K., Ito, M., Nagata, T., Kaneko, K., Miyazaki, K., Okada, A., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0128657 · Cited by 99 · see citing works
ZnO and TiO2 nanoparticles as novel antimicrobial agents for oral hygiene: a review
Khan, S. T., Al-Khedhairy, A. A., & Musarrat, J. (2015) · Journal of Nanoparticle Research · doi:10.1007/s11051-015-3074-6 · Cited by 100 · see citing works
Denitrification in human dental plaque
Schreiber, F., Stief, P., Gieseke, A., Heisterkamp, I. M., Verstraete, W., de Beer, D., & Stoodley, P. (2010) · BMC Biology · doi:10.1186/1741-7007-8-24 · Cited by 90 · see citing works
Specific Lactobacillus/Mutans Streptococcus Co-aggregation
Lang, C., Böttner, M., Holz, C., Veen, M., Ryser, M., Reindl, A., Pompejus, M., & Tanzer, J. M. (2010) · Journal of Dental Research · doi:10.1177/0022034509356246 · Cited by 83 · see citing works
Visualization of initial bacterial colonization on dentine and enamel in situ
Jung, D. J., Al-Ahmad, A., Follo, M., Spitzmüller, B., Hoth-Hannig, W., Hannig, M., & Hannig, C. (2010) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2010.03.002 · Cited by 61 · see citing works
DNA from human ancient bacteria: a novel source of genetic evidence from archaeological dental calculus
DE LA FUENTE, C., FLORES, S., & MORAGA, M. (2013) · Archaeometry · doi:10.1111/j.1475-4754.2012.00707.x · Cited by 57 · see citing works
Metabolic Interactions between Bacteria and Fungi in Commensal Oral Biofilms
Lof, M., Janus, M., & Krom, B. (2017) · Journal of Fungi · doi:10.3390/jof3030040 · Cited by 51 · see citing works
Genetic analysis of Treponema denticola ATCC 35405 biofilm formation
Vesey, P. M., & Kuramitsu, H. K. (2004) · Microbiology · doi:10.1099/mic.0.26816-0 · Cited by 45 · see citing works
Coaggregation of oral pathogens by postbiotic lactobacilli
Golletz, P., Jensen, S. D., Collignon, M., Hall, C., Khamas, A. B., Møllebjerg, A., Schlafer, S., Meyer, R. L., & Tykwinska, K. (2025) · Journal of oral microbiology · doi:10.1080/20002297.2025.2508483 · Cited by 10 · see citing works
“…of halitosis [15–17] and gingivitis [18,19] (1) Fusobacterium nucleatum , a spindle-shaped bacterium with multi-species coaggregation interactions [20,21] that usually resides in the middle of dental biofilms where it bridges early and late colonizers [22], and recruits (2) Porphyromonas…”
Flipping DNA to generate and regulate microbial consortia
Ramadas, R., & Thattai, M. (2010) · Genetics · doi:10.1534/genetics.109.105999 · Cited by 7 · see citing works

Advances in studies of quorum-sensing autoinducer and its inhibitors
Chen, W. (2007) · Shengming kexue · Cited by 1 · see citing works
Small Molecule Inhibitors of Bacterial Quorum Sensing and Biofilm Formation
Geske, G. D., Wezeman, R. J., Siegel, A. P., et al. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0530321 · Cited by 320 · see citing works
LuxS quorum sensing: more than just a numbers game
Xavier, K. B., & Bassler, B. L. (2003) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(03)00028-6 · Cited by 750 · see citing works
A review article: Anti-quorum sensing agents as a potential replacement for antibiotics in Phytobacteriology
Verma, R., Das, A. K., Sarmah, D., et al. (2021) · The Pharma Innovation · doi:10.22271/tpi.2021.v10.i11b.9200 · Cited by 9 · see citing works
Quorum Sensing in Bacteria
Miller, M. B., & Bassler, B. L. (2001) · Annual Review of Microbiology · doi:10.1146/annurev.micro.55.1.165 · Cited by 5,127 · see citing works

Authors: Kolenbrander, P. E., Andersen, R. N., Blehert, D. S., Egland, P. G., Foster, J. S., & Palmer, R. J.
Affiliations: National Institutes of Health (US)
Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892
ORCID: Blehert, David S.
Egland, Paul G.
Foster, Jamie S.
Venue: Microbiology and Molecular Biology Reviews
Publisher: American Society for Microbiology
Published: 2002-09
Volume: 66
Issue: 3
Pages: 486-505
ISSN: 1092-2172 (ISSN-L)
1098-5557
DOI: 10.1128/mmbr.66.3.486-505.2002
PMC: PMC120797
OpenAlex: W2123937142
Cited by: 1,022
References: 156
Citations by year: 2026: 18 · 2025: 28 · 2024: 40 · 2023: 28 · 2022: 49 · 2021: 56 · 2020: 67 · 2019: 64 · 2018: 55 · 2017: 49 · 2016: 34 · 2015: 36 · 2014: 66 · 2013: 53 · 2012: 50
FWCI: 1.88
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Microbiology and Molecular Biology Reviews (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Keywords: bacterial communication, quorum sensing, oral bacteria, dental plaque, autoinducer-2, cell-to-cell communication, adhesins, biofilm structure, host-bacteria interactions, gene expression regulation
MeSH terms: Amino Acid Sequence, Antigens, Bacterial, Bacteria, Homoserine, Humans, Lactones, Models, Biological, Molecular Sequence Data, Mouth, Streptococcus, Signal Transduction, Bacterial Physiological Phenomena

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