A Physical Activity and Diet Program Delivered by Artificially Intelligent Virtual Health Coach: Proof-of-Concept Study
Open accessPublished version of a preprint
Abstract
Background: Poor diet and physical inactivity are leading modifiable causes of death and disease. Advances in artificial intelligence technology present tantalizing opportunities for creating virtual health coaches capable of providing personalized support at scale. Objective: This proof of concept study aimed to test the feasibility (recruitment and retention) and preliminary efficacy of physical activity and Mediterranean-style dietary intervention (MedLiPal) delivered via artificially intelligent virtual health coach. Methods: This 12-week single-arm pre-post study took place in Adelaide, Australia, from March to August 2019. Participants were inactive community-dwelling adults aged 45 to 75 years, recruited through news stories, social media posts, and flyers. The program included access to an artificially intelligent chatbot, Paola, who guided participants through a computer-based individualized introductory session, weekly check-ins, and goal setting, and was available 24/7 to answer questions. Participants used a Garmin Vivofit4 tracker to monitor daily steps, a website with educational materials and recipes, and a printed diet and activity log sheet. Primary outcomes included feasibility (based on recruitment and retention) and preliminary efficacy for changing physical activity and diet. Secondary outcomes were body composition (based on height, weight, and waist circumference) and blood pressure. Results: Over 4 weeks, 99 potential participants registered expressions of interest, with 81 of those screened meeting eligibility criteria. Participants completed a mean of 109.8 (95% CI 1.9-217.7) more minutes of physical activity at week 12 compared with baseline. Mediterranean diet scores increased from a mean of 3.8 out of 14 at baseline, to 9.6 at 12 weeks (mean improvement 5.7 points, 95% CI 4.2-7.3). After 12 weeks, participants lost an average 1.3 kg (95% CI –0.1 to –2.5 kg) and 2.1 cm from their waist circumference (95% CI –3.5 to –0.7 cm). There were no significant changes in blood pressure. Feasibility was excellent in terms of recruitment, retention (90% at 12 weeks), and safety (no adverse events). Conclusions: An artificially intelligent virtual assistant-led lifestyle-modification intervention was feasible and achieved measurable improvements in physical activity, diet, and body composition at 12 weeks. Future research examining artificially intelligent interventions at scale, and for other health purposes, is warranted.
AI snapshot
Written from the paper’s full text.
TL;DR
This 12-week single-arm proof-of-concept study tested an artificially intelligent virtual health coach, Paola, delivering a physical activity and Mediterranean-style diet program to inactive adults aged 45–75. The intervention was feasible and was associated with improvements in physical activity, diet adherence, weight, and waist circumference, with no significant blood pressure changes.
Key findings
- Feasibility was strong: 99 potential participants expressed interest within 4 weeks, 31 were enrolled, and retention was 90% at 12 weeks (28/31 attended); no adverse events occurred.
- Physical activity increased by 109.8 minutes/week from baseline to week 12 (95% CI 1.9–217.7, P=.005).
- Mediterranean diet adherence rose from 3.8/14 at baseline to 9.6/14 at 12 weeks, a mean improvement of 5.7 points (95% CI 4.2–7.3, P<.001).
- Participants lost an average 1.3 kg (95% CI –2.5 to –0.1, P=.01) and 2.1 cm in waist circumference (95% CI –3.5 to –0.7, P=.003); blood pressure did not change significantly. Engagement averaged 6.9 of 11 weekly check-ins (64%), below the a priori 70% target.
Methods
- Design: 12-week single-arm pre-post proof-of-concept study conducted in Adelaide, Australia, from March to August 2019.
- Participants: 31 inactive community-dwelling adults aged 45–75 recruited through news stories, social media, and flyers; eligibility required not meeting Australian physical activity guidelines and not following a Mediterranean dietary pattern.
- Intervention and analysis: participants used Paola, a natural language processing virtual health coach built with IBM Watson and deployed on Slack, plus a Garmin Vívofit4 tracker, MedLiPal website, and diet/activity log. Feasibility was analyzed descriptively; efficacy used unadjusted repeated measures ANOVA on an intention-to-treat basis with last observation carried forward, plus complete-case sensitivity analyses.
Limitations
- Stated in the paper: the pre-post design lacked a randomized control comparator, and follow-up was limited to three months.
- Evident from the text: the sample was small (n=31) and mostly women (21/31), primary outcomes were self-reported via the Active Australia Survey and a Mediterranean diet questionnaire, engagement fell below the a priori target (64% vs 70%), and 3 participants had minimal smartphone skills while technical problems with Slack or the software sometimes interrupted check-ins.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
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Claims the paper makes
0 of 27 cited sources checked · 0 supported · 0 flagged
- Findingnone given
No adverse events related to study participation were experienced.
“No adverse events related to study participation were experienced.”
Quote in the paperNot a substantial claim - Findingown data
Overall, from baseline to 12 weeks, physical activity increased by 109.8 minutes (95% CI 1.9 to 217.7, P=.005).
“Thus overall, from baseline to 12 weeks, physical activity increased by 109.8 minutes (95% CI 1.9 to 217.7, P=.005).”
- Also stated in: § Results · plain
“Participants completed a mean of 109.8 (95% CI 1.9-217.7) more minutes of physical activity at week 12 compared with baseline.”
Quote in the paperSubstantial claim - Also stated in: § Results · plain
- Findingown data
Engagement with the virtual health coach was slightly lower than the a priori threshold of ≥70% (actual completion rate 64%).
“Engagement with the virtual health coach (based on completed weekly check-ins) was slightly lower than our a priori threshold of ≥70% (actual completion rate 64%).”
Quote in the paperSubstantial claim - Findingown data
Mean change in Mediterranean diet adherence from baseline to 12 weeks was 5.7 points (95% CI 4.2 to 7.3, P<.001).
“(mean change baseline to 12 weeks 5.7, 95% CI 4.2 to 7.3, P<.001).”
- Also stated in: § Results · plain
“Mediterranean diet scores increased from a mean of 3.8 out of 14 at baseline, to 9.6 at 12 weeks (mean improvement 5.7 points, 95% CI 4.2-7.3).”
Quote in the paperSubstantial claim - Also stated in: § Results · plain
- Findingown data
Participants completed an average of 6.9 out of 11 possible weekly check-ins (64%, range 1-11).
“Out of a maximum of 11 possible check-ins, participants completed an average of 6.9 (64%, range 1-11).”
Quote in the paperNot a substantial claim
- Findingown data
No adverse events occurred.
“Feasibility was excellent in terms of recruitment, retention (90% at 12 weeks), and safety (no adverse events).”
Quote in the paperSubstantial claim - Findingown data
There was no change in blood pressure (diastolic or systolic) at either time point.
“There was no change in blood pressure (diastolic or systolic) at either time point.”
Quote in the paperNot a substantial claim - Findingown data
Participants who completed the first weekly check-in had significantly higher engagement across the intervention period than those who did not (mean 7.4, SD 3.4 vs mean 4.6, SD 2.6; P=.03).
“Participants who completed the first weekly check-in had significantly higher engagement across the intervention period than those who did not complete the first weekly check-in (mean 7.4, SD 3.4 vs mean 4.6, SD 2.6; P=.03).”
Quote in the paperNot a substantial claim - Findingown data
Retention was 90% at 12 weeks.
“Feasibility was excellent in terms of recruitment, retention (90% at 12 weeks), and safety (no adverse events).”
Quote in the paperSubstantial claim - Findingown data
Systolic blood pressure did not change significantly across the 12-week intervention (overall F(2,29)=0.11, P=.90).
“| SBPc (mmHg) | 125.7 (12.8) | 124.9 (14.5) | 125.5 (13.8) | 0.11,.90 | –0.8 (–4.9 to 3.4) | –0.2 (–5.7 to 5.3) |”
Quote in the paperNot a substantial claim - Findingown data
Diastolic blood pressure did not change significantly across the 12-week intervention (overall F(2,29)=0.64, P=.54).
“| DBPd (mmHg) | 82.8 (7.9) | 81.8 (9.3) | 81.8 (8.8) | 0.64, .54 | –1.0 (–3.4 to 1.3) | –1.0 (–4.3 to 2.4) |”
Quote in the paperNot a substantial claim - Findingcitation
The sample had physical activity rates comparable to other Australian studies of older adults measured using the AAS.
“and physical activity rates comparable to other Australian studies of older adults measured using the AAS [31-33].”
Quote in the paperNot a substantial claim0 of 3 sources checked - Findingcitation
The sample exhibited above-average rates of obesity and overweight compared with population norms.
“They also exhibited above-average rates of obesity and overweight compared with population norms [30]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [30] 2019, Canberra, AIHW
Not checked in the free run.
- Findingcitation
The sample had poor adherence to Australian healthy eating guidelines (baseline average self-reported vegetable servings 2.2/day and fruit 1.3/day compared to recommended 5 and 2 servings/day).
“Our sample had poor adherence to Australian healthy eating guidelines (baseline average self-reported vegetable servings was 2.2/day and fruit 1.3/day compared to the recommended 5 and 2 servings per day, respectively) [29].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [29] 2013, Canberra, NHRMC
Not checked in the free run.
- Study design and conductnone given
For efficacy outcomes, the sample size of n=30, assuming 80% power, an alpha of 0.05, and a single group design with three repeated measures, was able to detect an effect size of d=0.48.
“For efficacy outcomes, this sample size, assuming 80% power, an alpha of 0·05, and a single group design with three repeated measures, was able to detect an effect size of d=0.48.”
Quote in the paperSubstantial claim - Interpretationreasoning
To the authors' knowledge, there are currently no published studies examining fully automated, natural language processing artificial intelligence health coaches for lifestyle modification.
“To our knowledge, there are currently no published studies examining fully automated, natural language processing artificial intelligence health coaches for lifestyle modification.”
Quote in the paperSubstantial claim - Study design and conductcitation
The Australian Mediterranean diet adherence tool has been validated relative to the Mediterranean diet score calculated from a 3-day weighed food record, with r=0.44.
“The Australian Mediterranean diet adherence tool has been validated relative to the Mediterranean diet score calculated from a 3-day weighed food record r=0.44 [26].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] source
Not checked in the free run.
- Interpretationown data
The study found high retention across the 12-week study period.
“The study found a high level of interest in the technology-based intervention approach amongst the target demographic and high retention across the 12-week study period.”
Quote in the paperSubstantial claim - Interpretationown data
The study found a high level of interest in the technology-based intervention approach amongst the target demographic.
“The study found a high level of interest in the technology-based intervention approach amongst the target demographic and high retention across the 12-week study period.”
Quote in the paperNot a substantial claim - Premisecitation
Health systems' finite budgets typically limit access to specialized support services from health professionals to specific patient populations, such as those with established chronic disease.
“However, health systems’ finite budgets typically limit access to such services to specific patient populations, such as those with established chronic disease [5].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [5] Chronic Disease Management - Provider InformationAustralian Government, Department of Health20142019-08-31https://www1.health.gov.au/internet/main/publishing.nsf/Content/mbsprimarycare-factsheet-chronicdisease.htm
Not checked in the free run.
- Interpretationreasoning
This population appears ideally suited to this type of new offering, given they are not unwell enough to qualify for face-to-face services yet have modifiable risk factors for chronic diseases.
“This population appears to be ideally suited to this type of new offering, given that they are not unwell enough to qualify for face-to-face services through the health system, yet have modifiable risk factors for the future development of chronic diseases such as type 2 diabetes and cardiovascular disease.”
Quote in the paperSubstantial claim- Rests on an assumption: The study sample is representative of older adults generally.
- Study design and conductnone given
The study used intention-to-treat analysis, which ensures that the intervention effects are not over-estimated.
“Other study strengths include its mostly hands-off approach (thus improving the ecological validity of the study compared with a study with a high level of human contact), the use of objective health measures, and the use of intention-to-treat analysis, which ensures that the intervention effects are not over-estimated.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Artificial intelligence technology may be able to provide practical, supportive dietary counseling at a low cost.
“These exciting findings suggest that artificial intelligence technology may be able to provide practical, supportive dietary counseling at a low cost.”
Quote in the paperSubstantial claim - Interpretationcitation
Improvement in Mediterranean diet adherence was much more significant than those achieved by previous technology-based Mediterranean diet interventions.
“Improvement in Mediterranean diet adherence was much more significant than those achieved by previous technology-based Mediterranean diet interventions [40,41].”
Quote in the paperSubstantial claim0 of 2 sources checked - Study design and conductnone given
The study used objective health measures.
“Other study strengths include its mostly hands-off approach (thus improving the ecological validity of the study compared with a study with a high level of human contact), the use of objective health measures, and the use of intention-to-treat analysis, which ensures that the intervention effects are not over-estimated.”
Quote in the paperNot a substantial claim - Study design and conductnone given
Follow-up was limited to three months.
“Limitations include the pre-post design, which meant the study lacked a randomized control comparator, and follow-up is limited to three months.”
Quote in the paperNot a substantial claim - Interpretationcitation
The degree of behavior change achieved was approximately in line with that reported in previous studies using intensive one-on-one dietary counseling.
“The degree of behavior change achieved was approximately in line with that reported in previous studies using intensive one-on-one dietary counseling [26,42].”
Quote in the paperSubstantial claim0 of 2 sources checked - Interpretationown data
Results suggest there is considerable enthusiasm amongst older adults for this style of intervention.
“Results suggest there is considerable enthusiasm amongst older adults for this style of intervention and confirm that most older adults have sufficient skills to access a virtual health coach program and use it effectively to achieve sizeable behavior and health change.”
Quote in the paperSubstantial claim- Rests on an assumption: The study sample is representative of older adults generally.
- Interpretationown data
Getting participants to complete their first independent check-in successfully may be a strong predictor of ongoing engagement.
“It appears that getting participants to complete their first independent check-in successfully may be a strong predictor of ongoing engagement, and a specific target in future program iterations.”
Quote in the paperSubstantial claim
- May combine two claims. 33
- Classified as probably not a substantial claim. 15
May combine two claims.
Findingown dataFrom baseline to week 6, weekly physical activity increased by approximately one hour, and then by a further 50 minutes at 12 weeks.
“From baseline to week 6, weekly physical activity increased by approximately one hour, and then by a further 50 minutes at 12 weeks.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataAround 70% of participants completed check-ins in weeks two, three, four and 12, with engagement sliding to around 50% through weeks eight and nine, before rising again in the final weeks.
“Around 70% of participants completed the check-ins in weeks two, three, four and 12, with engagement gradually sliding to around 50% through weeks eight and nine, before rising again in the final weeks of the program.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
FindingcitationUsing an identical search strategy, the authors updated the review in January 2020 and identified a further 11 studies; most recent studies were aimed at mental health self-management (n=5).
“Using an identical search strategy, we updated this review in January 2020 and identified a further 11 studies. Similar to the previous review, most recent studies were aimed at mental health self-management (n=5) [10-12].”
Quote in the paperNot a substantial claim0 of 3 sources checkedMay combine two claims.
Findingown dataWeekly total moderate and vigorous physical activity increased from baseline to week 12 by 109.8 minutes (95% CI 1.9 to 217.7), with overall model F(2,29)=6.45, P=.005.
“| Weekly total MVPAb minutes (min) | 206.1 (166.5) | 266.8 (207.2) | 315.9 (261.7) | 6.45, .005 | 60.8 (–21.7 to 143.3) | 109.8 (1.9 to 217.7) |”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataWaist circumference decreased from baseline to week 6 by 1.0 cm (95% CI -1.8 to -0.1) and to week 12 by 2.1 cm (95% CI -3.5 to -0.7), overall F(2,29)=7.13, P=.003.
“| Waist circumference (cm) | 96.0 (16.0) | 95.1 (15.8) | 93.9 (15.8) | 7.13,.003 | –1.0 (–1.8 to –0.1) | –2.1 (–3.5 to –0.7) |”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataOf 31 participants enrolled, 3 had minimal smartphone skills and were reliant on partners or children to use their phones as part of the study.
“Of the 31 participants meeting all eligibility criteria and enrolled in the study, it became clear during baseline appointments that 3 participants had minimal smartphone skills (eg, did not know how to send a text message or download an app). These participants were reliant on their partners or children to use their phones as part of the study.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe first 38 potential participants completed the eligibility screening interview, of which 31 (82%) were eligible.
“The first 38 potential participants completed the eligibility screening interview, of which 31 (82%) were eligible.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataWeight decreased from baseline to week 6 by 1.1 kg (95% CI -2.0 to -0.3) and to week 12 by 1.3 kg (95% CI -2.5 to -0.1), overall F(2,29)=5.41, P=.01.
“| Weight (kg) | 83.6 (19.0) | 82.4 (18.3) | 82.3 (18.1) | 5.41,.01 | –1.1 (–2.0 to –0.3) | –1.3 (–2.5 to –0.1) |”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataA total of 99 potential participants formally expressed their interest in the study within four weeks of recruitment opening, at which point expressions of interest were closed.
“A total of 99 potential participants formally expressed their interest in the study within four weeks of recruitment opening, at which point expressions of interest were closed.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataWaist circumference decreased by 1 cm from baseline to week 6, and then another 1 cm to week 12, leading to an overall loss of -2.1 cm (95% CI -3.5 to -0.7, P=.003).
“Similarly, waist circumference decreased by 1 cm from baseline to week 6, and then another 1 cm to week 12, leading to an overall loss of –2.1cm (95% CI –3.5 to –0.7, P=.003).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataOn average, participants lost 1.1 kg from baseline to week 6, and then lost a further 0.2 kg to week 12, resulting in an overall average loss of 1.3 kg (95% CI -2.5 to -0.7, P=.01).
“On average, participants lost 1.1 kg from baseline to week 6, and then lost a further 0.2 kg to week 12, resulting in an overall average loss of 1.3 kg (95% CI –2·5 to –0·7, P=.01).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataMediterranean diet adherence score increased from baseline to week 6 by 6.0 points (95% CI 4.3 to 7.7) and to week 12 by 5.7 points (95% CI 4.2 to 7.3), overall F(2,29)=44.56, P<.001.
“| Mediterranean diet adherence score (out of 14) | 3.8 (1.8) | 9.8 (3.7) | 9.6 (3.1) | 44.56, <.001 | 6.0 (4.3 to 7.7) | 5.7 (4.2 to 7.3) |”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataParticipants were sequentially booked for baseline assessments until the study quota of 30 participants was filled, with n=31 ultimately enrolled.
“Participants were sequentially booked for baseline assessments until the study quota of 30 participants was filled, with n=31 ultimately enrolled.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataMediterranean diet adherence increased markedly from baseline to week 6 and then was approximately maintained from week 6 to week 12.
“Mediterranean diet adherence increased markedly from baseline to week 6 and then was approximately maintained at this level from week 6 to week 12”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe most significant drop off with the virtual health coach occurred between the baseline appointment and week two, with around a quarter of participants failing to complete the first weekly check-in.
“Interestingly, the most significant drop off with the virtual health coach occurred between the baseline appointment and week two of the program (ie, the first check-in participants were supposed to complete on their own), with around a quarter of participants failing to complete the first weekly check-in.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataAt the 6-week assessment, several participants reported difficulty consuming the recommended number of food group servings due to feeling satiated.
“At the 6-week assessment, several participants reported difficultly consuming the recommended number of food group servings (due to feeling satiated).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingnone givenTechnical problems with Slack or the software interrupted attempts to check in, which generally were rectified after week 1.
“In some cases, technical problems with Slack or the software interrupted attempts to check in, which generally were rectified after week 1.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThree participants who enrolled had very low smartphone literacy at baseline, which impacted their ability to use the program as intended.
“Three participants who enrolled in the study were found to have very low smartphone literacy at the baseline session, which impacted their ability to use the program as intended.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationThe study attracted mostly women, who were similar to national averages for socioeconomic advantage.
“Our study attracted mostly women, who were similar to national averages for socioeconomic advantage (national average 1000) [28].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [28] Australian Bureau of Statistics (ABS)ABS2033.0.55.001 - Census of Population and Housing: Socio-economic Indexes for Areas (SEIFA)20162019-09-20https://www.abs.gov.au/AUSSTATS/abs@.nsf/DetailsPage/2033.0.55.0012016?OpenDocumOpe
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May combine two claims.
Interpretationown dataFeasibility was excellent in terms of recruitment, retention, and safety.
“Feasibility was excellent in terms of recruitment, retention (90% at 12 weeks), and safety (no adverse events).”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataAn artificially intelligent virtual assistant-led lifestyle-modification intervention was feasible and achieved measurable improvements in physical activity, diet, and body composition at 12 weeks.
“An artificially intelligent virtual assistant-led lifestyle-modification intervention was feasible and achieved measurable improvements in physical activity, diet, and body composition at 12 weeks.”
Quote in the paperSubstantial claim- Rests on an assumption: The observed improvements in physical activity, diet, and body composition are attributable to the MedLiPal intervention rather than to secular trends, regression to the mean, or other factors.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationIn highly developed countries, over ninety percent of Australian adults fail the recommended daily intake of vegetables and fruit, and approximately two-thirds do not meet guidelines of 30 min of physical activity most days.
“In highly developed countries, these unfavorable health behaviors are pervasive; for example, over ninety percent of Australian adults fail the recommended daily intake of vegetables and fruit, and approximately two-thirds do not meet guidelines of 30 min of physical activity most days [2,3].”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [2] 4364.0.55.003 - Australian Health Survey: Updated Results, 2011-2012. Daily Intake of Fruit and Vegetables20132019-09-01Australian Bureau of Statisticshttps://www.abs.gov.au/ausstats/abs@.nsf/Lookup/C549D4433F6B74D7CA257B8200179569?opendocument
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- cites [3] 4364.0.55.001 - Australian Health Survey: First Results, 2011-1220122019-08-31Australian Bureau of Statisticshttps://www.abs.gov.au/ausstats/abs@.nsf/Lookup/4364.0.55.001main+features12011-12
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May combine two claims.
PremisecitationLaranjo and colleagues' 2018 systematic review of studies evaluating natural language processing virtual assistants in healthcare identified just 14 studies, most of which focused on mental health (n=6) or clinician decision making (n=4).
“Laranjo and colleagues’ 2018 systematic review of studies evaluating natural language processing virtual assistants in healthcare identified just 14 studies, most of which focused on mental health (n=6) or clinician decision making (n=4) [9].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] source
Not checked in the free run.
May combine two claims.
PremisecitationWeight-loss virtual assistant Lark led to significant weight loss, comparable in magnitude to that achieved in in-person lifestyle interventions.
“For example, weight-loss virtual assistant “Lark” led to significant weight loss, comparable in magnitude to that achieved in in-person lifestyle interventions.[6]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [6] source
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
Study design and conductnone givenThe target sample size was set at n=30, which was considered adequate to answer feasibility research questions.
“The target sample size was set at n=30, which was considered adequate to answer feasibility research questions.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationPerceived relevance and the inclusion of social support are associated with increased effect sizes in digital behavior change interventions.
“Compared to more traditional knowledge transfer methods in digital health (eg, tailored modules), the conversational methods in virtual assistance may be perceived as more personally relevant and humanistic, which is critical given that perceived relevance and the inclusion of social support are associated with increased effect sizes in digital behavior change interventions [7,8].”
Quote in the paperSubstantial claim0 of 2 sources checkedMay combine two claims.
Interpretationown dataPreliminary evidence suggests that the intervention led to sizable improvements in physical activity, diet, and body composition across 12 weeks.
“Preliminary evidence suggests that the intervention led to sizable improvements in physical activity, diet, and body composition across 12 weeks.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataMissing data were imputed using the last observation carried forward.
“Given that a small amount of data was missing (16% missing data at week 6, 10% at week 12 for primary outcomes), imputation was achieved using the last observation carried forward.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationLark only allowed users to respond to program-directed questions and did not allow users to ask questions.
“However, Lark only allowed users to respond to program-directed questions and did not allow users to ask questions.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [6] source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataSensitivity analyses using complete cases were conducted.
“Sensitivity analyses using complete cases were also conducted.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationPoor diet and physical inactivity are among the leading modifiable causes of death and disease and increase the risk of chronic health conditions such as type 2 diabetes, cardiovascular disease, obesity, cancers, depression, and anxiety.
“Poor diet and physical inactivity are amongst the leading modifiable causes of death and disease and increase the risk of developing chronic health conditions such as type 2 diabetes, cardiovascular disease, obesity, cancers, depression, and anxiety [1].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Remington, P, 2010, Chronic Disease Epidemiology and Control source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataAttendance for the 6- and 12-week assessments was 29 and 28, respectively.
“Attendance for the 6- and 12-week assessments was 29 and 28, respectively (Figure 2).”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductnone givenEfficacy was assessed using an unadjusted repeated measures ANOVA, conducted on an intention-to-treat principle.
“Efficacy was assessed using an unadjusted repeated measures ANOVA, conducted on an intention-to-treat principle.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductreasoningThe study had a pre-post design, which meant the study lacked a randomized control comparator.
“Limitations include the pre-post design, which meant the study lacked a randomized control comparator, and follow-up is limited to three months.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataThe study confirmed that a virtual health coach diet and physical activity intervention is feasible for older adults and leads to sizable health behavior change and improvements in body composition.
“This ground-breaking study confirmed that a virtual health coach diet and physical activity intervention is feasible for older adults and leads to sizable health behavior change and improvements in body composition.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataMost older adults have sufficient skills to access a virtual health coach program and use it effectively to achieve sizeable behavior and health change.
“Results suggest there is considerable enthusiasm amongst older adults for this style of intervention and confirm that most older adults have sufficient skills to access a virtual health coach program and use it effectively to achieve sizeable behavior and health change.”
Quote in the paperSubstantial claim- Rests on an assumption: The study sample is representative of older adults generally.
May combine two claims.
Study design and conductreasoningThe study had a mostly hands-off approach, improving ecological validity compared with a study with a high level of human contact.
“Other study strengths include its mostly hands-off approach (thus improving the ecological validity of the study compared with a study with a high level of human contact), the use of objective health measures, and the use of intention-to-treat analysis, which ensures that the intervention effects are not over-estimated.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. May combine two claims.
PremisereasoningThe virtual health coach used natural language processing, which allows users to converse using freely written language, representing a significant advancement over previous computer-tailoring approaches.
“Our virtual health coach used natural language processing, which allows users to converse using freely written language, representing a significant advancement over previous computer-tailoring approaches, which typically rely on multiple choice.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataThe magnitude of change in physical activity was similar to or larger than that achieved in previous computer-tailoring interventions.
“The magnitude of change in physical activity was similar to [36,37] or larger than [38,39] that achieved in previous computer-tailoring interventions.”
Quote in the paperSubstantial claim0 of 4 sources checked
The paper relies on this without support.
A future definitive trial with a dedicated recruitment budget should be able to recruit approximately 400 participants over a year if 30 participants can be recruited in 6 weeks with no advertising budget.
“We sought to recruit 30 participants to the study within 6 weeks, on the rationale that if this could be achieved with no advertising budget, a future definitive trial with a dedicated recruitment budget should be able to recruit approximately 400 participants over a year.”
The paper relies on this without support.
The observed improvements in physical activity, diet, and body composition are attributable to the MedLiPal intervention rather than to secular trends, regression to the mean, or other factors.
“An artificially intelligent virtual assistant-led lifestyle-modification intervention was feasible and achieved measurable improvements in physical activity, diet, and body composition at 12 weeks.”
The paper relies on this without support.
The virtual health coach intervention is the first study to evaluate an advanced virtual assistant technology for delivering a personalized lifestyle intervention among older adults.
“To our knowledge, this is the first study to evaluate the capacity of an advanced virtual assistant technology to deliver a personalized lifestyle intervention amongst older adults.”
The paper relies on this without support.
The study sample is representative of older adults generally.
“Results suggest there is considerable enthusiasm amongst older adults for this style of intervention and confirm that most older adults have sufficient skills to access a virtual health coach program and use it effectively to achieve sizeable behavior and health change.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Among non-RCT studies, Maher et al and Brar Prayaga et al reported highest compliance (5/9, 56%), followed by Masaki et al, Prochaska et al, and To et al (4/9, 44%).
“Among the non-RCT studies, the studies by Maher et al [22] and Brar Prayaga et al [30] reported the highest compliance (5/9, 56%), followed closely by the studies by Masaki et al [25], Prochaska et al [31], and To et al [32] (4/9, 44%).”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
The Methods (Power and Statistical Analyses; page unavailable) describe a single-group design, supporting the classification of Maher et al as a non-RCT study. The paper does not report compliance of 5/9 (56%) or compare its compliance with the other named studies; those parts of the citing sentence are not supported by this source. (LLM, conf=0.82)
Experimental — accuracy not yet measuredIn one of these studies, the engagement rates decreased gradually as the intervention progressed, and in the other study, the engagement rates decreased significantly by midprogram but increased to 70% in the final week, that is, the 12th week.
“In one of these studies, the engagement rates decreased gradually as the intervention progressed [23], and in the other study, the engagement rates decreased significantly by midprogram but increased to 70% in the final week, that is, the 12th week [22].”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredThe need for greater interactivity can also be associated with the fluctuations in user engagement found in 13% (2/15) of studies.
“The need for greater interactivity can also be associated with the fluctuations in user engagement found in 13% (2/15) of studies [22,23].”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
The Results section, “Engagement With the Virtual Health Coach” (page unavailable), reports that weekly check-in engagement fell from around 70% to 50% before rising again, supporting the reported fluctuation. The paper does not link that pattern to a need for greater interactivity; its Discussion instead considers first-check-in difficulties, smartphone literacy, and technical problems. As a single study, it also does not report the citing document’s 2/15-studies figure. (LLM, conf=0.86)
Experimental — accuracy not yet measuredIn 20% (3/15) of studies, the humanistic yet nonhumanistic construct of AI chatbots provided a safe space for the users to discuss, share, and ask for information on sensitive issues.
“Third, in 20% (3/15) of studies, the humanistic yet nonhumanistic construct of AI chatbots provided a safe space for the users to discuss, share, and ask for information on sensitive issues [5,22,23,35].”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
The Introduction (page unavailable) says conversational virtual assistants may feel more humanistic, and Results > Other Feasibility Issues (page unavailable) reports that participants were encouraged to ask the coach for dietary advice. Neither passage establishes that the coach provided a safe space to discuss or share sensitive issues; searches for that experience found no supporting passage. The 3/15 figure describes the citing authors’ set of studies, rather than a result this individual study would be expected to report. (LLM, conf=0.79)
Experimental — accuracy not yet measuredMaher et al reported an increase in physical activity by 109.8 minutes (P=.005) and a decrease in average weight and waist circumference by 1.3 kg (P=.01) and 2.1 cm (P=.003), respectively.
“Maher et al [22] reported an increase in physical activity by 109.8 minutes (P=.005) and a decrease in the average weight and waist circumference by 1.3 kg (P=.01) and 2.1 cm (P=.003), respectively.”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
Maher et al reported an increase in the mean of Mediterranean diet scores by 5.7 points (P<.001).
“Maher et al [22] reported an increase in the mean of Mediterranean diet (healthy meal) scores by 5.7 points (P<.001).”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
Of the 15 studies, 7 (47%) targeted healthy lifestyles, and 5 (33%) assessed efficacy of AI chatbots in promoting healthy lifestyles.
“Out of the 15 studies, 7 (47%) studies [5,21,22,28,29,32,33] targeted healthy lifestyles, and 5 (33%) studies [21,22,28,32,33] assessed the efficacy of AI chatbots in promoting healthy lifestyles through (1) physical activity levels, (2) healthy diet, (3) blood pressure, and (4) BMI.”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
20% (3/15) of studies reported an improvement in diet.
“Second, 20% (3/15) of studies [22,28,33] reported an improvement in diet.”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
Maher et al assessed blood pressure after intervention as a secondary outcome; mean improvement in systolic blood pressure (-0.2 mmHg; P=.90) and diastolic blood pressure (−1.0 mmHg; P=.54) were not significant.
“Third, Maher et al [22] assessed blood pressure level after intervention as a secondary outcome; however, the mean improvement in systolic blood pressure (-0.2 mmHg; P=.90) and diastolic blood pressure (−1.0 mmHg; P=.54) were not significant.”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
Of the 15 studies, 11 (73%) reported feasibility of AI chatbots in terms of safety, messages exchanged, retention rate, and duration of engagement.
“Out of the 15 studies, 11 (73%) reported the feasibility of AI chatbots in terms of (1) safety [22] (ie, no adverse events were reported), (2) messages exchanged with the chatbot [6,26,29,31,32], (3) retention rate [22,26], and (4) duration of engagement.”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
Only 7% (1/15) of studies reported the chatbot's safety in terms of absence of adverse events.
“Only 7% (1/15) of studies [22] reported the chatbot’s safety in terms of the absence of adverse events.”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
Only 7% (1/15) of studies, that is, the study by Maher et al, reported safety in terms of the absence of adverse events.
“Only 7% (1/15) of studies, that is, the study by Maher et al [22], reported safety in terms of the absence of adverse events.”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
In the case of feasibility, evidence on the safety of chatbots was quite less because only 7% (1/15) of studies reported safety.
“In the case of feasibility, evidence on the safety of chatbots was quite less because only 7% (1/15) of studies reported safety [22].”
From Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review. (2023) · cites this paper as [22]
The Results (Adverse Events; page unavailable) report no adverse events in this study. The Introduction mentions a review of 14 studies, but neither passage says that only 1 of 15 studies reported safety; searches for the 7% figure and safety reporting across studies found no supporting passage. (LLM, conf=0.78)
Experimental — accuracy not yet measuredIn a proof-of-concept study of the Paola chatbot, participants reported relevant weight loss and improved diet.
“The results showed that participants reported relevant weight loss and improved diet.”
AI chatbots have great potential to increase the accessibility and efficacy of personalized lifestyle modification programs.
“These limitations can be overcome by utilizing AI chatbots, which have great potential to increase the accessibility and efficacy of personalized lifestyle modification programs [20, 21].”
From A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss (2021) · cites this paper as [20]
One chatbot communicated only on a weekly basis.
“One chatbot communicated only on a weekly basis [20], and 1 communicated daily, weekly, on weekends or weekdays or at a scheduled date and time [35].”
From A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss (2021) · cites this paper as [20]
AI chatbots provide new communication modalities for individuals to receive, comprehend, and utilize information, suggestions, and assistance on a personal level.
“Furthermore, AI chatbots provide new communication modalities for individuals to receive, comprehend, and utilize information, suggestions, and assistance on a personal level [20, 22], which can help overcome one’s lack of self-efficacy or social support [20].”
From A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss (2021) · cites this paper as [20]
AI chatbots can help overcome a person's lack of self-efficacy or social support.
“Furthermore, AI chatbots provide new communication modalities for individuals to receive, comprehend, and utilize information, suggestions, and assistance on a personal level [20, 22], which can help overcome one’s lack of self-efficacy or social support [20].”
From A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss (2021) · cites this paper as [20]
One study used multi-intervention components, and participants had access to an AI chatbot along with a study website with educational materials.
“One study used multi-intervention components, and participants had access to an AI chatbot along with a study website with educational materials [20].”
From A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss (2021) · cites this paper as [20]
The effect measured by the Fitbits appeared to be smaller, as the average step count only increased by approximately 600 steps/day or 4200 steps/week, which roughly corresponds to an increase of 42 minutes of physical activity per week.
“However, the effect measured by the Fitbits appeared to be smaller, as the average step count only increased by approximately 600 steps/day or 4200 steps/week, which roughly corresponds to an increase of 42 minutes of physical activity per week (assuming it takes approximately 10 minutes to take 1000 steps) [20].”
From Feasibility, Usability, and Effectiveness of a Machine Learning–Based Physical Activity Chatbot: Quasi-Experimental Study (2021) · cites this paper as [20]
The effect on self-reported physical activity in this study (approximately 160 min/week) was similar to an increase of approximately 110 min/week of physical activity measured by accelerometers after a 12-week intervention in another study.
“The effect on self-reported physical activity in this study (approximately 160 min/week) was similar to an increase of approximately 110 min/week of physical activity measured by accelerometers after a 12-week intervention in another study [20].”
From Feasibility, Usability, and Effectiveness of a Machine Learning–Based Physical Activity Chatbot: Quasi-Experimental Study (2021) · cites this paper as [20]
These findings are consistent with those from another Australian study examining a combined diet and physical activity chatbot using natural language processing.
“These findings are consistent with those from another Australian study examining a combined diet and physical activity chatbot using natural language processing [20].”
From Feasibility, Usability, and Effectiveness of a Machine Learning–Based Physical Activity Chatbot: Quasi-Experimental Study (2021) · cites this paper as [20]
That study also included a large dietary component and allowed more time (12 weeks) for weight loss to occur.
“However, that study also included a large dietary component and allowed more time (12 weeks) for weight loss to occur [20].”
From Feasibility, Usability, and Effectiveness of a Machine Learning–Based Physical Activity Chatbot: Quasi-Experimental Study (2021) · cites this paper as [20]
This is different from the other Australian chatbot-based physical activity interventions, which showed a significant decrease in weight at week 12.
“This is different from the other Australian chatbot-based physical activity interventions, which showed a significant decrease in weight at week 12 [20].”
From Feasibility, Usability, and Effectiveness of a Machine Learning–Based Physical Activity Chatbot: Quasi-Experimental Study (2021) · cites this paper as [20]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Average check-in completion percentage does not match the count
MinorAn average of 6.9 out of 11 check-ins is 62.7%, not 64%; rounding the reported average to one decimal place cannot account for the difference.
Reported 64 · recomputed 62.727273
“Out of a maximum of 11 possible check-ins, participants completed an average of 6.9 (64%, range 1-11).”
Study design described as both case-controlled and single-arm
MinorThe Methods calls the study case-controlled, but the abstract describes it as a single-arm pre-post study. A single-arm study has no control group.
“The case-controlled study was approved by the University of South Australia Human Research Ethics Committee (ref 201724).”
“This 12-week single-arm pre-post study took place in Adelaide, Australia, from March to August 2019.”
Weight-loss confidence interval differs from Table 2
MinorThe Results text gives an upper confidence limit of -0.7 kg for the 12-week weight change, whereas Table 2 gives -0.1 kg.
“resulting in an overall average loss of 1.3 kg (95% CI –2·5 to –0·7, P=.01).”
“–1.3 (–2.5 to –0.1)”
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- Authors
- Maher, C. A., Davis, C. R., Curtis, R. G., Short, C. E., & Murphy, K. J.
- Affiliations
- University of South Australia (AU)
- The University of Melbourne (AU)
- Corresponding author
- Maher, Carol Ann
- ORCID
- Venue
- JMIR mHealth and uHealth
- Publisher
- JMIR Publications Inc.
- Published
- 2020-07-10
- Volume
- 8
- Issue
- 7
- Pages
- e17558
- ISSN
- 2291-5222 (ISSN-L)
- PMC
- PMC7382010
- OpenAlex
- W3021104312
- Semantic Scholar
- 91d0e592da91fb71eb86f81c409d9529875b3c30
- Cited by
- 165
- References
- 35
- Citations by year
- 2026: 38 · 2025: 51 · 2024: 22 · 2023: 29 · 2022: 12 · 2021: 11 · 2020: 2
- FWCI
- 14.05
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- JMIR mhealth and uhealth (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- UniSA Research Outputs Repository (University of South Australia) (submittedVersion, other-oa)
- Funders
- University of South Australia
- Medical Research Council
- National Health and Medical Research Council (1125913)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Health Professions › Health Information Management › Innovation in Digital Healthcare Systems
- Keywords
- artificial intelligence, chatbots, physical activity, Mediterranean diet, lifestyle modification, body composition, weight loss, blood pressure, older adults, feasibility, recruitment and retention, wearable activity trackers, personalized health interventions, goal setting, community-dwelling adults, sedentary behavior, diet quality, waist circumference, body mass index, digital health interventions, proof of concept
- MeSH terms
- Proof of Concept Study, Adult, Aged, Artificial Intelligence, Australia, Blood Pressure, Body Composition, Diet, Female, Health Promotion, Humans, Male, Middle Aged, Exercise
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