Cited by 349Adrenal and Paraganglionic TumorsAdrenal Hormones and DisordersHormonal Regulation and Hypertension

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Nonfunctioning adrenal masses: incidental discovery on computed tomography

Glazer, HS, Weyman, PJ, Sagel, SS, Levitt, RG, McClennan, BL·1982·American Journal of Roentgenology

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Abstract

Sixteen adrenal masses were identified with computed tomography (CT) in patients who had no clinical or biochemical evidence of adrenal pathology. In five patients, an adrenalectomy was performed, disclosing either an adenoma or nodular hyperplasia. Autopsy disclosed a cortical adenoma in one patient who died from unrelated causes. In the remaining 10 patients, follow-up scans 4--16 months later revealed no change in the size of the masses. A management plan of nonfunctioning adrenal masses discovered incidentally on CT is proposed.

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“Glazer et al. 1982 (17) 16/2200 0.60 Printz et al. 1982 (18) 4/1423 0.35 Abecassis et al. 1985 (13) 19/1459 1.30 Belldegrun et al. 1986 (19) 88/12 000 0.70 Herrera et al. 1991 (20) 259/61 054 0.42 Caplan et al. 1994 (21) 33/1779 1.90 Total 531/82 483 0.64 www.eje.org Downloaded from…”
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“functioning adenoma [1].”
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“The clinical relevance of SH is still debated (5).”
Background
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“Glazer 1982 NA 2200 NA NA NA 0.6 NA NA Prinz 1982 1981 1423 41 – 73 44.4 Abdominal 0.6 10-40 0 Abecassis 1985 1983- 1985 1459 NA NA NA 1.3 NA NA Belldegrun 1986 1976- 1983 12000 NA NA Abdominal 0.7 NA NA Herrera 1991 1985- 1989 61054 62 60.2 NA 0.4 25 (10- 110) NA Caplan 1994 NA 1779 NA NA NA 1.90…”
BackgroundInfluential
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Background
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Method
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Untitled work
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Background
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“nologic importance have been widely discussed [2-33].”
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Background
Accuracy of several parameters of hypothalamic-pituitary-adrenal axis activity in predicting before surgery the metabolic effects of the removal of an adrenal incidentaloma.
Eller-Vainicher, C., Morelli, V., Salcuni, A. S., Battista, C., Torlontano, M., Coletti, F., Iorio, L., Cairoli, E., Beck-Peccoz, P., Arosio, M., et al. (2010) · European Journal of Endocrinology · doi:10.1530/eje-10-0602 · Cited by 73
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Singh, P. K., & Buch, H. (2008) · Journal of Clinical Pathology · doi:10.1136/jcp.2006.044313 · Cited by 70
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Dieckmann, K., Hamm, B., Pickartz, H., et al. (1987) · Urology · doi:10.1016/0090-4295(87)90587-5 · Cited by 65
The Adrenal Incidentaloma
Graham, D. J., & McHenry, C. R. (1998) · Surgical Oncology Clinics of North America · doi:10.1016/s1055-3207(18)30243-6 · Cited by 66
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Seppel, T., & Schlaghecke, R. (1994) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1994.tb02575.x · Cited by 63
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Carpenter, P. C. (1986) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)61398-6 · Cited by 63
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Jockenhövel, F., Kuck, W., Hauffa, B. P., Reinhardt, W., Benker, G., Lederbogen, S., Olbricht, T., & REINWEIN, D. (1992) · Journal of Endocrinological Investigation · doi:10.1007/bf03348745 · Cited by 61
Pitfalls of adrenal imaging with chemical shift MRI
Schieda, N., Dandan, O. S. A., Kielar, A. Z., Flood, T. A., McInnes, M. D. F., & Siegelman, E. S. (2014) · Clinical Radiology · doi:10.1016/j.crad.2014.06.020 · Cited by 62
Evaluation of hormonal function in a series of incidentally discovered adrenal masses.
Bondanelli, M., Campo, M., Trasforini, G., Ambrosio, M. R., Zatelli, M. C., Franceschetti, P., Valentini, A., Pansini, R., & Uberti, E. C. D. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90176-1 · Cited by 61
Imaging of incidentally discovered adrenal masses
Peppercorn, P. D., Grossman, A. B., & Reznek, R. H. (1998) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1998.00475.x · Cited by 59
Clinical Study of Adrenal Incidentaloma in Korea
Kim, H. Y., Kim, S. G., Lee, K. W., Seo, J. A., Kim, N. H., Choi, K. M., Baik, S. H., & Choi, D. S. (2005) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2005.20.4.303 · Cited by 62
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Lubitz, C. C., Economopoulos, K. P., Sy, S., Johanson, C., Kunzel, H. E., Reincke, M., Gazelle, G. S., Weinstein, M. C., & Gaziano, T. A. (2015) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.115.002002 · Cited by 63
Evaluation of adrenal masses with gadolinium enhancement and fat‐suppressed MR imaging
Semelka, R. C., Shoenut, J. P., Lawrence, P. H., et al. (1993) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.1880030208 · Cited by 61
Reconsidering the necessity of ipsilateral adrenalectomy during radical nephrectomy for renal cell carcinoma.
Leibovitch, I., Raviv, G., Mor, Y., et al. (1995) · Urology · doi:10.1016/s0090-4295(99)80213-1 · Cited by 62
The adrenal gland
Reznek, R. H., & Armstrong, P. (1994) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1994.tb03006.x · Cited by 57
“…in adrenal disorders not resulting in increased hormonal activity Adenoma Adrenal nodules with a diameter of 1-3 cm are detected incidentally in 0.6-1 % of upper abdominal CT examinations performed for indications other than detecting adrenal disease (Glazer et al., 1982; Ambos et ul., 1981).”
BackgroundMethodInfluential
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Lee, J. A. (2007) · Archives of Surgery · doi:10.1001/archsurg.142.9.870 · Cited by 58
Endocrine activity of the “silent” adrenocortical adenoma is uncovered by response to corticotropin-releasing hormone
Hensen, J., Buhl, M., Bähr, V., & Oelkers, W. (1990) · Journal of Molecular Medicine · doi:10.1007/bf01660959 · Cited by 57
“In about 1% of all abdominal CTs performed, an adrenal mass is discovered incidentally [14, 28].”
Background
MR imaging of the adrenal glands
Hussain, H. K., & KOROBKIN, M. T. (2004) · Magnetic Resonance Imaging Clinics of North America · doi:10.1016/j.mric.2004.03.008 · Cited by 54
“5% of the population during abdominal CT [57].”
Background
How Accurate Is Computed Tomography in Predicting the Real Size of Adrenal Tumors?
Linos, D. A. (1997) · Archives of Surgery · doi:10.1001/archsurg.1997.01430310054009 · Cited by 54
Adrenal "incidentalomas". Need for surgery.
Seddon, J. M., Baranetsky, N., & Boxel, P. V. (1985) · Urology · doi:10.1016/0090-4295(85)90552-7 · Cited by 52
Cortisol Secretion by an Incidentally Discovered Nonfunctional Adrenal Adenoma*
BEYER, H. S., & DOE, R. P. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-62-6-1317 · Cited by 52
The computed tomography-guided adrenal biopsy: An alternative to surgery in adrenal mass diagnosis
Berkman, W. A., Bernardino, M. E., Sewell, C. W., Price, R. B., & Sones, P. J. (1984) · Cancer · doi:10.1002/1097-0142(19840515)53:10 · Cited by 50
DIAGNOSIS AND TREATMENT OF ADRENAL INCIDENTALOMA
Kievit, J., & Haak, H. R. (2000) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70117-1 · Cited by 52
Low dehydroepiandrosterone sulfate (DHEA-S) level is not a good predictor of hormonal activity in nonselected patients with incidentally detected adrenal tumors
Bencsik, Z., Szabolcs, I., Kovács, Z., Ferencz, A., Vörös, A., Kaszás, I., Bor, K., Gönczi, J., Góth, M., Kovács, L., et al. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.5.8626824 · Cited by 49
The value of dehydroepiandrosterone sulfate measurement in the differentiation between benign and malignant adrenal masses
Terzolo, M., Ali, A., Osella, G., Reimondo, G., Pia, A., Peretti, P., Paccotti, P., & Angeli, A. (2000) · European Journal of Endocrinology · doi:10.1530/eje.0.1420611 · Cited by 47
The value of CT scanning and percutaneous fine needle aspiration of adrenal masses in biopsy-proven lung cancer.
Gillams, A., Roberts, C., Shaw, P., et al. (1992) · Clinical Radiology · doi:10.1016/s0009-9260(05)80027-3 · Cited by 58
Imaging evaluation of the non-functioning indeterminate adrenal mass
Sahdev, A., & Reznek, R. H. (2004) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2004.06.012 · Cited by 48
Clinical significance of the large adrenal mass
Khafagi, F. A., Gross, M. D., Shapiro, B., et al. (1991) · British journal of surgery · doi:10.1002/bjs.1800780720 · Cited by 49
State-of-the-art CT and MRI of the adrenal gland
Peppercorn, P. D., & Reznek, R. H. (1997) · European Radiology · doi:10.1007/s003300050214 · Cited by 47
Strategies for the management of recurrent and advanced urologic cancers. Quality of life
Herr, H. W. (1987) · Cancer · doi:10.1002/1097-0142(19870801)60:3+ · Cited by 15
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Rosen, H. N., & Swartz, S. L. (1992) · The American Journal of Medicine · doi:10.1016/0002-9343(92)90115-r · Cited by 42
Differentiation of Adrenal Adenoma and Nonadenoma in Unenhanced CT: New Optimal Threshold Value and the Usefulness of Size Criteria for Differentiation
Park, S. H., Kim, M., Kim, J. H., Lim, J. S., & Kim, K. W. (2007) · Korean Journal of Radiology · doi:10.3348/kjr.2007.8.4.328 · Cited by 39
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Background
Expression of steroidogenic enzyme messenger ribonucleic acids and corticosteroid production in aldosterone-producing and "nonfunctioning" adrenal adenomas
Rácz, K., Pinet, F., Marton, T., Szende, B., Gláz, E., & Corvol, P. L. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.77.3.8370688 · Cited by 43
Computed Tomography of the Body
WITTENBERG, J. (1983) · New England Journal of Medicine · doi:10.1056/nejm198311173092006 · Cited by 39
The indeterminate adrenal lesion
Sahdev, A., Willatt, J. M., Francis, I. R., & Reznek, R. H. (2010) · Cancer Imaging · doi:10.1102/1470-7330.2010.0012 · Cited by 39
“The incidence of adrenal masses increases to 9 13% in patients with a known underlying malignancy([1,2]).”
Background
Scintigraphic studies in adrenal hypertension
Gross, M. D., & Shapiro, B. (1989) · Seminars in Nuclear Medicine · doi:10.1016/s0001-2998(89)80007-8 · Cited by 39
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Bendinelli, C., Lucchi, M., Buccianti, P., et al. (1998) · Journal of Laparoendoscopic & Advanced Surgical Techniques · doi:10.1089/lap.1998.8.119 · Cited by 39
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McAlister, F. A., & Lewanczuk, R. Z. (1998) · Europe PMC (PubMed Central) · Cited by 38
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Little, A. G., & Stitik, F. P. (1990) · CHEST Journal · doi:10.1378/chest.97.6.1431 · Cited by 38
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Bitter, D. A., & Ross, D. S. (1989) · The American Journal of Surgery · doi:10.1016/0002-9610(89)90367-x · Cited by 37
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Wand, G. S., & Ney, R. L. (1985) · Clinics in Endocrinology and Metabolism · doi:10.1016/s0300-595x(85)80064-5 · Cited by 36
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Lavoie, H. B., & Lacroix, A. (1995) · Trends in Endocrinology and Metabolism · doi:10.1016/1043-2760(95)00091-u · Cited by 37
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Ettaieb, M. H. T., Kerkhofs, T. M. A., van Engeland, M., & Haak, H. R. (2020) · Cancers · doi:10.3390/cancers12051218 · Cited by 37
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Murai, M., Baba, S., Nakashima, J., & Tachibana, M. (1999) · World Journal of Urology · doi:10.1007/s003450050098 · Cited by 34
Bilateral adrenal lesions
Gupta, P., Bhalla, A. S., & Sharma, R. (2012) · Journal of Medical Imaging and Radiation Oncology · doi:10.1111/j.1754-9485.2012.02435.x · Cited by 43

Authors: Glazer, H., Weyman, P., Sagel, S., Levitt, R., & McClennan, B.
Venue: American Journal of Roentgenology
Publisher: American Roentgen Ray Society
Published: 1982-07-01
Volume: 139
Issue: 1
Pages: 81-85
ISSN: 0002-9580 (ISSN-L)
0361-803X
1546-3141
DOI: 10.2214/ajr.139.1.81
OpenAlex: W2171882916
Cited by: 347
References: 0
Citations by year: 2025: 6 · 2024: 2 · 2023: 6 · 2022: 4 · 2021: 2 · 2020: 8 · 2019: 4 · 2018: 5 · 2017: 5 · 2016: 6 · 2015: 3 · 2014: 6 · 2013: 2 · 2012: 4
FWCI: 13.86
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Roentgenology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
Keywords: incidental adrenal findings, adrenal adenoma, adrenal nodular hyperplasia, adrenalectomy, follow-up imaging, adrenal cortex
MeSH terms: Adenoma, Adrenal Cortex, Adrenal Cortex Neoplasms, Adult, Aged, Female, Humans, Hyperplasia, Male, Middle Aged, Tomography, X-Ray Computed

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Nonfunctioning adrenal masses: incidental discovery on computed tomography

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