The DOI matches its Crossref record; 76 of the 77 references it cites were found in a registry or an index.
Clearance Properties of Nano-Sized Particles and Molecules as Imaging Agents: Considerations and Caveats
Open accessAbstract
Nanoparticles possess enormous potential as diagnostic imaging agents and hold promise for the development of multimodality agents with both imaging and therapeutic capabilities. Yet, some of the most promising nanoparticles demonstrate prolonged tissue retention and contain heavy metals. This presents serious concerns for toxicity. The creation of nanoparticles with optimal clearance characteristics will minimize toxicity risks by reducing the duration of exposure to these agents. Given that many nanoparticles possess easily modifiable surface and interior chemistry, if nanoparticle characteristics associated with optimal clearance from the body were well established, it would be feasible to design and create agents with more favorable clearance properties. This article presents a thorough discussion of the physiologic aspects of nanoparticle clearance, focusing on renal mechanisms, and provides an overview of current research investigating clearance of specific types of nanoparticles and nano-sized macromolecules, including dendrimers, quantum dots, liposomes and carbon, gold and silica-based nanoparticles.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Due to the threshold for rapid renal excretion being about 5.5 nm, the hydrodynamic diameters of the prepared nanoparticles need to be larger than this size [168–170].”
From Non-viral delivery systems for CRISPR/Cas9-based genome editing: challenges and opportunities (2018) · cites this paper as [169]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Renal clearance of quantum dots
Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476
A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors
Hardman, R. C. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.8284 · Cited by 2,304
Nanoengineering of optical resonances
Oldenburg, S. J., Averitt, R. D., Westcott, S. L., & Halas, N. J. (1998) · Chemical Physics Letters · doi:10.1016/s0009-2614(98)00277-2 · Cited by 2,266
Particle size-dependent organ distribution of gold nanoparticles after intravenous administration
de Jong, W. H., Hagens, W. I., Krystek, P., Burger, M. C., Sips, A. J. A. M., & Geertsma, R. E. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2007.12.037 · Cited by 1,620
Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)
Szoka, F. C., & Papahadjopoulos, D. (1980) · Annual Review of Biophysics and Bioengineering · doi:10.1146/annurev.bb.09.060180.002343 · Cited by 1,515
Recent advances in iron oxide nanocrystal technology for medical imaging☆
Corot, C., Robert, P., Idée, J., & Port, M. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.09.013 · Cited by 1,461
Gold nanoparticles: a new X-ray contrast agent
Hainfeld, J. F., Slatkin, D. N., Focella, T. M., & Smilowitz, H. M. (2006) · British Journal of Radiology · doi:10.1259/bjr/13169882 · Cited by 1,351
Malik, N., Wiwattanapatapee, R., Klopsch, R., Lorenz, K., Frey, H., Weener, J.-W., Meijer, E. W., Paulus, W., & Duncan, R. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00246-1 · Cited by 1,228
Noninvasive Imaging of Quantum Dots in Mice
Ballou, B. T., Lagerholm, B. C., Ernst, L. A., Bruchez, M. P., & Waggoner, A. S. (2003) · Bioconjugate Chemistry · doi:10.1021/bc034153y · Cited by 1,141
Liu, Z., Davis, C. R., Cai, W., He, L., Chen, X.-Y., & Dai, H. (2008) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0707654105 · Cited by 1,097
Flagged first, then by citations
1 of the 77 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- 10.1021/ja027555 · DOI
- Wisse E DoucetD Van Bossuyt H: A transmission electron microscopic study on the uptake of AMI-25 by sinusoidal liver cells. In: Cells of the Hepatic Sinusoid (Volume 3). Wisse E Knook DL McCuskey RS (Eds.). The Kupffer Cell Foundation Leiden The Netherlands 534–539 (1991).
Cited by
Sorted by citations
Items 601–700 of 1,000
Blau, R., Krivitsky, A., Epshtein, Y., & Satchi‐Fainaro, R. (2016) · Drug Resistance Updates · doi:10.1016/j.drup.2016.06.003 · Cited by 79
Jain, A., Fournier, P. G. J., Mendoza-Lavaniegos, V., Sengar, P., Guerra-Olvera, F. M., Iñiguez, E., Kretzschmar, T. G., Hirata, G. A., & Juárez, P. (2018) · Journal of Nanobiotechnology · doi:10.1186/s12951-018-0359-9 · Cited by 60
Kang, S. J., Jeong, H. Y., Kim, M. W., Jeong, I. H., Choi, M. J., You, Y. M., Im, C. S., Song, I. H., Lee, T. S., & Park, Y. S. (2018) · Nanoscale · doi:10.1039/c8nr05099f · Cited by 60
Platinum nanoplatforms: classic catalysts claiming a prominent role in cancer therapy
García-Peiro, J. I., Bonet‐Aleta, J., Santamarı́a, J., & Hueso, J. L. (2022) · Chemical Society Reviews · doi:10.1039/d2cs00518b · Cited by 59
Serum Protein Adsorption and Excretion Pathways of Metal Nanoparticles
Vinluan, R. D., & Zheng, J. (2015) · Nanomedicine · doi:10.2217/nnm.15.97 · Cited by 60
Biodistribution of Antibody-MS2 Viral Capsid Conjugates in Breast Cancer Models
Aanei, I. L., ElSohly, A. M., Farkas, M. E., Netirojjanakul, C., Regan, M., Murphy, S. T., O’Neil, J. P., Seo, Y., & Francis, M. B. (2016) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.6b00566 · Cited by 59
Kim, S., Lee, B. R., Lee, H., Jo, S. D., Kim, H., Won, Y., & Lee, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-17714-2 · Cited by 59
Thinking about Enhanced Permeability and Retention Effect (EPR)
Leporatti, S. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12081259 · Cited by 58
Not so innocent: Impact of fluorophore chemistry on the in vivo properties of bioconjugates
Usama, S. M., Thapaliya, E. R., Luciano, M., & Schnermann, M. J. (2021) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2021.01.009 · Cited by 58
A biodegradable and rechargeable fiber battery
Mei, T., Wang, C., Liao, M., Li, J., Wang, L., Tang, C., Sun, X., Wang, B., & Peng, H. (2021) · Journal of Materials Chemistry A · doi:10.1039/d1ta01507a · Cited by 59
Aziz, T., Farid, A., Haq, F., Kiran, M., Ullah, N., Faisal, S., Ali, A., Khan, F. U., You, S., Bokhari, A., et al. (2023) · Environmental Research · doi:10.1016/j.envres.2023.115253 · Cited by 58
Inorganic lanthanide nanoprobes for background-free luminescent bioassays
Huang, P., Tu, D., Zheng, W., Zhou, S., Chen, Z., & Chen, X. (2015) · Science China Materials · doi:10.1007/s40843-015-0019-4 · Cited by 58
Focused ultrasound-enabled delivery of radiolabeled nanoclusters to the pons
Ye, D., Sultan, D. H., Zhang, X., Yue, Y., Heo, G. S., Kothapalli, S. V. V. N., Luehmann, H. P., Tai, Y., Rubin, J. B., Liu, Y., et al. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.05.039 · Cited by 58
Jiang, X., Han, Y., Zhang, H., Liu, H., Huang, Q., Wang, T., Sun, Q., & Li, Z. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b15064 · Cited by 58
Aborig, M., Malik, P. R. V., Nambiar, S., Chelle, P., Darko, J., Mutsaers, A. J., Edginton, A. N., Fleck, A., Osei, E. K., & Wettig, S. D. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11040179 · Cited by 61
Lee, H., Shahrivarkevishahi, A., Lumata, J. L., Luzuriaga, M. A., Hagge, L. M., Benjamin, C., Brohlin, O. R., Parish, C. R., Firouzi, H. R., Nielsen, S. O., et al. (2020) · Chemical Science · doi:10.1039/c9sc05510j · Cited by 58
Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs
Kokkinos, J., Ignacio, R. M. C., Sharbeen, G., Boyer, C. A., Gonzales‐Aloy, E., Goldstein, D., Initiative, A. P. C. G., McCarroll, J. A., & Phillips, P. A. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2019.119742 · Cited by 57
Lysosomal nanotoxicity: Impact of nanomedicines on lysosomal function
Uzhytchak, M., Smolková, B., Lunová, M., Frtús, A., Jirsa, M., Dejneka, A., & Lunov, O. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114828 · Cited by 61
Unraveling the in vivo fate of inhaled micro- and nanoplastics with PET imaging
Delaney, S., Rodríguez, C. M. A., Sarrett, S. M., Dayts, E. J., Zeglis, B. M., & Keinänen, O. M. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.166320 · Cited by 58
Spleen-targeted delivery systems and strategies for spleen-related diseases
Huang, Z., Sun, K., Luo, Z., Zhang, J., Zhou, H., Yin, H., Liang, Z., & You, J. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.05.007 · Cited by 56
Ultrathin Iron Oxide Nanowhiskers as Positive Contrast Agents for Magnetic Resonance Imaging
Macher, T., Totenhagen, J. W., Sherwood, J. A., Qin, Y., Gurler, D., Bolding, M., & Bao, Y. (2014) · Advanced Functional Materials · doi:10.1002/adfm.201403436 · Cited by 58
Zhou, Z., & Lu, Z. (2014) · Nanomedicine · doi:10.2217/nnm.14.133 · Cited by 57
de Menezes, F. D., dos Reis, S. R. R., Pinto, S. R., Portilho, F. L., Mello, F. D. V. C. E., Helal‐Neto, E., de Barros, A. O. D. S., Alencar, L. M. R., de Menezes, A. S., dos Santos, C. C., et al. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.04.058 · Cited by 57
Qu, G., Wang, X., Liu, Q. S., Liu, R., Yin, N., Ma, J., Chen, L., He, J., Liu, S., & Jiang, G. (2013) · Journal of Environmental Sciences · doi:10.1016/s1001-0742(12)60252-6 · Cited by 56
Wei, Y., Liao, R., Mahmood, A. A., Xu, H., & Zhou, Q. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.03.046 · Cited by 56
Stenström, P., Manzanares, D., Zhang, Y., Ceña, V., & Malkoch, M. (2018) · Molecules · doi:10.3390/molecules23082028 · Cited by 57
Guo, S., Xu, C., Yin, H., Hill, J. L., Pi, F., & Guo, P. (2019) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1582 · Cited by 57
Surface-Engineered Cancer Nanomedicine: Rational Design and Recent Progress
Ahmad, J., Zafar, A., Ahmad, M. Z., & Akhter, M. H. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200214110645 · Cited by 56
Gold Nanoparticles: A New Golden Era in Oncology?
Gerosa, C., Crisponi, G., Nurchi, V. M., Saba, L., Cappai, R., Cau, F., Faa, G., Eyken, P. V., Scartozzi, M., Floris, G., et al. (2020) · Pharmaceuticals · doi:10.3390/ph13080192 · Cited by 58
Injectables and Depots to Prolong Drug Action of Proteins and Peptides
Ibeanu, N., Egbu, R., Onyekuru, L., Javaheri, H., Khaw, P. T., Williams, G. R., Brocchini, S., & Awwad, S. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12100999 · Cited by 56
Towards a unified approach in the modeling of fibrosis: A review with research perspectives
Amar, M. B., & Bianca, C. (2016) · Physics of Life Reviews · doi:10.1016/j.plrev.2016.03.005 · Cited by 57
Jing, X., Zhi, Z., Zhang, N., Song, H., Xu, Y., Zhou, G., Wang, D., Shao, Y., & Meng, L. (2019) · Chemical Engineering Journal · doi:10.1016/j.cej.2019.123893 · Cited by 55
Kwak, G., Grewal, A., Slika, H., Mess, G., Li, H., Kwatra, M., Poulopoulos, A., Woodworth, G. F., Eberhart, C. G., Ko, H. S., et al. (2024) · ACS Nano · doi:10.1021/acsnano.4c05270 · Cited by 59
Recent advances in nanogels for drug delivery and biomedical applications
Vashist, A., Alvarez, G. P., Camargo, V. A., Raymond, A., Yndart, A., Kolishetti, N., Vashist, A., Manickam, P., Aggarwal, S., & Nair, M. (2024) · Biomaterials Science · doi:10.1039/d4bm00224e · Cited by 55
Biophysical, biopharmaceutical and toxicological significance of biomedical nanoparticles
Aula, S., Lakkireddy, S., Jamil, K., Kapley, A., Swamy, A. V. N., & Reddy, L. H. (2015) · RSC Advances · doi:10.1039/c5ra05889a · Cited by 57
Özçelikkale, A., Ghosh, S., & Han, B. (2013) · Molecular Pharmaceutics · doi:10.1021/mp3005947 · Cited by 55
Gadolinium( iii ) based nanoparticles for T 1 -weighted magnetic resonance imaging probes
Yang, C., Padmanabhan, P., & Gulyás, B. Z. (2016) · RSC Advances · doi:10.1039/c6ra07782j · Cited by 57
Zhang, S., Chen, H., Zhang, G., Kong, X., Yin, S., Li, B., & Wu, L. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb02743e · Cited by 55
Takeuchi, T., Iizumi, Y., Yudasaka, M., Kizaka‐Kondoh, S., & Okazaki, T. (2019) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.9b00088 · Cited by 59
Wang, Z., Zhang, M., Chi, S., Zhu, M., Wang, C., & Liu, Z. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202200521 · Cited by 54
Pevarnik, M., Schiel, M., Yoshimatsu, K., Vlassiouk, I., Kwon, J. S., Shea, K. J., & Siwy, Z. S. (2013) · ACS Nano · doi:10.1021/nn400774e · Cited by 54
Radionanomedicine: Widened perspectives of molecular theragnosis
Lee, D. S., Im, H., & Lee, Y. (2015) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2014.12.010 · Cited by 54
Martinez, J. O., Brown, B. S., Quattrocchi, N., Evangelopoulos, M., Mauro Ferrari, B., & Tasciotti, E. (2012) · Chinese Science Bulletin · doi:10.1007/s11434-012-5387-5 · Cited by 54
Nanoscale “fluorescent stone”: Luminescent Calcium Fluoride Nanoparticles as Theranostic Platforms
Li, Z., Zhang, Y., Huang, L. F., Yang, Y., Zhao, Y., El-Banna, G., & Han, G. (2016) · Theranostics · doi:10.7150/thno.15914 · Cited by 54
Nanoparticle delivery systems, general approaches, and their implementation in multiple myeloma
de la Puente, P., & Azab, A. K. (2017) · European Journal Of Haematology · doi:10.1111/ejh.12870 · Cited by 55
Kefayat, A., Ghahremani, F., Motaghi, H., & Mehrgardi, M. A. (2019) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2019.01.037 · Cited by 54
Comparative study of nanoparticle uptake and impact in murine lung, liver and kidney tissue slices
Bartucci, R., Paramanandana, A., Boersma, Y. L., Olinga, P., & Salvati, A. L. (2020) · Nanotoxicology · doi:10.1080/17435390.2020.1771785 · Cited by 54
Curcumin-loaded nanocomplexes: Acute and chronic toxicity studies in mice and hamsters
Jantawong, C., Priprem, A., Intuyod, K., Pairojkul, C., Pinlaor, P., Waraasawapati, S., Mongkon, I., Chamgramol, Y., & Pinlaor, S. (2021) · Toxicology Reports · doi:10.1016/j.toxrep.2021.06.021 · Cited by 53
Nanomedicines for Overcoming Cancer Drug Resistance
Hu, T., Gong, H., Xu, J., Huang, Y., Wu, F., & He, Z. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14081606 · Cited by 61
Tegafaw, T., Liu, S., Ahmad, M. Y., Saidi, A. K. A. A., Zhao, D., Liu, Y., Nam, S., Chang, Y., & Lee, G. H. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15061745 · Cited by 53
Dixon, A. J., Hu, S., Klibanov, A. L., & Hossack, J. A. (2015) · Small · doi:10.1002/smll.201403398 · Cited by 53
Sun, J., Xu, W., Li, L., Fan, B., Peng, X., Qu, B., Wang, L., Li, T., Li, S., & Zhang, R. (2018) · Nanoscale · doi:10.1039/c8nr01215f · Cited by 53
Non-coding RNAs: emerging biomarkers and therapeutic targets in cancer and inflammatory diseases
Abdelmonem, B. H., Kamal, L. T., Wardy, L. W., Ragheb, M., Hanna, M. M., Elsharkawy, M., & Abdelnaser, A. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1534862 · Cited by 55
Deconvoluting hepatic processing of carbon nanotubes
Alidori, S., Bowman, R. L., Yarilin, D. A., Romin, Y., Barlas, A., Mulvey, J. J., Fujisawa, S., Xu, K., Ruggiero, A., Riabov, V., et al. (2016) · Nature Communications · doi:10.1038/ncomms12343 · Cited by 52
Darvishi, B., Farahmand, L., & Majidzadeh‐A, K. (2017) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2017.03.007 · Cited by 53
Yu, Q., Xiong, X., Zhao, L., Xu, T., Bi, H., Fu, R., & Wang, Q. (2018) · Current Medical Science · doi:10.1007/s11596-018-1989-8 · Cited by 52
Zhu, Q., Xiahou, J., Guo, Y., Li, H., Ding, C., Wang, J., Li, X., Sun, X., & Li, J. (2018) · ACS Applied Bio Materials · doi:10.1021/acsabm.8b00734 · Cited by 52
Kaushik, A. K., Rodriguez, J. E., Rothen, D., Bhardwaj, V., Jayant, R. D., Pattany, P. M., Fuentes, B., Chand, H. S., Kolishetti, N., El‐Hage, N., et al. (2019) · ACS Applied Bio Materials · doi:10.1021/acsabm.9b00592 · Cited by 52
Rai, M., Bonde, S., Yadav, A., Plekhanova, Y. V., Reshetilov, A. N., Gupta, I. R., Golińska, P., Pandit, R., & Ingle, A. P. (2020) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2021.1836961 · Cited by 52
Exosome-like Nanoparticles: A New Type of Nanocarrier
Fernandes, M., Lopes, I., Teixeira, J., Botelho, C., & Gomes, A. C. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867326666190129142604 · Cited by 51
Combination Therapies and Drug Delivery Platforms in Combating Pancreatic Cancer
Lei, F., Xi, X., Batra, S. K., & Bronich, T. K. (2019) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.118.255786 · Cited by 51
Lin, G., Zhou, J., Cheng, H., & Liu, G. (2023) · Small · doi:10.1002/smll.202207973 · Cited by 52
Microfluidic technologies for lipid vesicle generation
Yu, C., Hay, C. D., Mahuttanatan, S. M., Hindley, J. W., Ces, O., & Elani, Y. (2024) · Lab on a Chip · doi:10.1039/d4lc00380b · Cited by 53
Chung, E. J., & Tirrell, M. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201500126 · Cited by 51
Synthesis and characterization of nanoparticles based on negatively charged xanthan gum and lysozyme
Xu, W., Jin, W., Li, Z., Liang, H., Wang, Y., Shah, B. R., Li, Y., & Li, B. (2015) · Food Research International · doi:10.1016/j.foodres.2015.02.007 · Cited by 51
Zhang, Y., Das, G. K., Vijayaragavan, V., Xu, Q. C., Padmanabhan, P., Bhakoo, K. K., Selvan, S. T., & Tan, T. T. Y. (2014) · Nanoscale · doi:10.1039/c4nr01717j · Cited by 51
Meissner, J. M., Toporkiewicz, M., Czogalla, A., Matusewicz, L., Kuliczkowski, K., & Sikorski, A. F. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.11.015 · Cited by 51
Renu, S., Rahman, P. K. S. M., Krishnamoorthy, V., Anusha, C., Kalaiarasi, A., Shivashangari, K. S., & Ravikumar, V. (2016) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2016.09.054 · Cited by 53
Xu, W., Sun, J., Li, L., Peng, X., Zhang, R., & Wang, B. (2017) · Biomaterials Science · doi:10.1039/c7bm00635g · Cited by 51
Locally anchoring enzymes to tissues via extracellular glycan recognition
Farhadi, S. A., Bracho-Sanchez, E., Fettis, M. M., Seroski, D. T., Macias, S. L., Restuccia, A., Keselowsky, B. G., & Hudalla, G. A. (2018) · Nature Communications · doi:10.1038/s41467-018-07129-6 · Cited by 51
Xiong, Y., Sun, F., Liu, P., Yang, Z., Cao, J., Liu, H., Liu, P., Hu, J., Xu, Z., & Yang, S. (2019) · Chemical Engineering Journal · doi:10.1016/j.cej.2019.122172 · Cited by 51
Engineered gadolinium-based nanomaterials as cancer imaging agents
Zeng, Y., Li, H., Li, Z., Luo, Q., Zhu, H., 顾, 忠., Zhang, H., Gong, Q., & Luo, K. (2020) · Applied Materials Today · doi:10.1016/j.apmt.2020.100686 · Cited by 53
Lymphatic immunomodulation using engineered drug delivery systems for cancer immunotherapy
Manspeaker, M. P., & Thomas, S. N. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.10.004 · Cited by 51
Manoharan, D., Wang, L., Chen, Y., Li, W., & Yeh, C. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400746 · Cited by 50
Multistage Nanoparticles for Improved Delivery into Tumor Tissue
Stylianopoulos, T., Wong, C., Bawendi, M. G., Jain, R. K., & Fukumura, D. (2012) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-391860-4.00006-9 · Cited by 52
Kim, H., Kim, J., Lee, M., Choi, H. C., & Kim, W. J. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201600246 · Cited by 50
Bioapplications of renal-clearable luminescent metal nanoparticles
Gong, L., Wang, Y., & Liu, J. (2017) · Biomaterials Science · doi:10.1039/c7bm00257b · Cited by 50
Simón‐Gracia, L., Scodeller, P., Fuentes, S. S., Gómez‐Vallejo, V., Ríos, X., Sebastián, E. S., Sidorenko, V., Silvio, D. D., Suck, M., Lorenzi, F. D., et al. (2018) · Oncotarget · doi:10.18632/oncotarget.24588 · Cited by 52
Yılmaz, M., Karanastasis, A. A., Chatziathanasiadou, Μ. V., Oğuz, M., Kougioumtzi, A., Clemente, N., Kellici, T. F., Zafeiropoulos, N. E., Avgeropoulos, A., Mavromoustakos, T., et al. (2019) · ACS Applied Bio Materials · doi:10.1021/acsabm.8b00748 · Cited by 50
Renal clearance of polymeric nanoparticles by mimicry of glycan surface of viruses
Wyss, P. P., Lamichhane, S. P., Abed, A., Vonwil, D., Kretz, O., Huber, T. B., Sarem, M., & Shastri, V. P. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119643 · Cited by 50
Rayamajhi, S., Marasini, R., Nguyen, T. D. T., Plattner, B. L., Biller, D. S., & Aryal, S. (2020) · Biomaterials Science · doi:10.1039/d0bm00128g · Cited by 50
Wang, L., Wan, Q., Zhang, R., Situ, B., Ni, K., Gao, J., Feng, X., Zhang, P., Wang, Z., Qin, A., et al. (2021) · ACS Nano · doi:10.1021/acsnano.1c01251 · Cited by 49
Ho, S. L., Cha, H., Oh, I. T., Jung, K., Kim, M. H., Lee, Y. J., Miao, X., Tegafaw, T., Ahmad, M. Y., Chae, K. S., et al. (2018) · RSC Advances · doi:10.1039/c8ra00553b · Cited by 49
Dendrimers against fungi – A state of the art review
Młynarczyk, D. T., Długaszewska, J., Kałużna-Młynarczyk, A., & Gośliński, T. A. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.12.021 · Cited by 52
Ultrasmall-in-Nano: Why Size Matters
Mellor, R. D., & Uchegbu, I. F. (2022) · Nanomaterials · doi:10.3390/nano12142476 · Cited by 51
Moradi, S., Akhavan, O., Tayyebi, A., Rahighi, R., Mohammadzadeh, M. J., & Rad, H. R. S. (2015) · RSC Advances · doi:10.1039/c5ra03331d · Cited by 49
Anderson, T., Hu, R., Yang, C., Yoon, H. S., & Yong, K. (2014) · Biomaterials Science · doi:10.1039/c4bm00019f · Cited by 50
Podhorodecki, A., Bański, M., Noculak, A., Sojka, B., Pawlik, G., & Misiewicz, J. (2012) · Nanoscale · doi:10.1039/c2nr32212a · Cited by 49
Zamproni, L. N., Mundim, M. V., Porcionatto, M. A., & Rieux, A. D. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.01.036 · Cited by 49
Developments and future clinical outlook of taxane nanomedicines
Louage, B., Wever, O. D., Hennink, W. E., & Geest, B. G. D. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.03.027 · Cited by 50
Nanotechnologies in Pancreatic Cancer Therapy
Manzur, A., Oluwasanmi, A., Moss, D. M., Curtis, A. D. M., & Hoskins, C. (2017) · Pharmaceutics · doi:10.3390/pharmaceutics9040039 · Cited by 52
Adamiak, L., Touve, M. A., LeGuyader, C. L. M., & Gianneschi, N. C. (2017) · ACS Nano · doi:10.1021/acsnano.7b03686 · Cited by 50
Cyclodextrin polymers as nanocarriers for sorafenib
Giglio, V., Viale, M., Bertone, V., Maric, I., Vaccarone, R., & Vecchio, G. (2017) · Investigational New Drugs · doi:10.1007/s10637-017-0538-9 · Cited by 49
Advances in biomedical and pharmaceutical applications of protein-stabilized gold nanoclusters
El‐Sayed, N., & Schneider, M. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01610a · Cited by 49
Akhter, M. H., Beg, S., Tarique, M., Malik, A., Afaq, S., Choudhry, H., & Hosawi, S. B. I. (2020) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2020.129777 · Cited by 51
Biological Applications of Thermoplasmonics
Ruhoff, V. T., Arastoo, M. R., Moreno-Pescador, G., & Bendix, P. M. (2024) · Nano Letters · doi:10.1021/acs.nanolett.3c03548 · Cited by 48
Color Doppler Ultrasound and Gamma Imaging of Intratumorally Injected 500 nm Iron–Silica Nanoshells
Liberman, A., Wu, Z. B., Barback, C. V., Viveros, R. D., Blair, S. L., Ellies, L. G., Vera, D. R., Mattrey, R. F., Kummel, A. C., & Trogler, W. C. (2013) · ACS Nano · doi:10.1021/nn402507d · Cited by 48
Wang, Y., Ji, L., Zhang, B., Yin, P., Qiu, Y., Song, D., Zhou, J., & Li, Q. (2013) · Nanotechnology · doi:10.1088/0957-4484/24/17/175101 · Cited by 48
Sharma, V. K., Alipour, A., Soran‐Erdem, Z., Aykut, G., & Demir, H. V. (2015) · Nanoscale · doi:10.1039/c5nr00752f · Cited by 50
Bakalova, R., Zhelev, Z., Kokuryo, D., Spasov, L., & Aoki, I. (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s17995 · Cited by 50
Metadata
- Authors
- Longmire, M., Choyke, P. L., & Kobayashi, H.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Kobayashi, Hisataka
- Venue
- Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2008-09-25
- Volume
- 3
- Issue
- 5
- Pages
- 703-717
- ISSN
- 1743-5889 (ISSN-L)
- 1748-6963
- PMC
- PMC3407669
- OpenAlex
- W2150146274
- Cited by
- 2,149
- References
- 77
- Citations by year
- 2026: 84 · 2025: 139 · 2024: 128 · 2023: 157 · 2022: 146 · 2021: 175 · 2020: 181 · 2019: 178 · 2018: 160 · 2017: 170 · 2016: 156 · 2015: 121 · 2014: 99 · 2013: 88 · 2012: 63
- FWCI
- 1.54
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nanomedicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (Z99 CA999999)
- National Cancer Institute (ZIABC010657)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Materials Science › General Materials Science › Nanotechnology research and applications
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Keywords
- nanoparticle clearance, diagnostic imaging agents, renal clearance, nanoparticle toxicity, heavy metals, dendrimers, quantum dots, liposomes, carbon nanoparticles, gold nanoparticles, silica nanoparticles, tissue retention
- MeSH terms
- Biocompatible Materials, Diagnostic Imaging, Gold, Humans, Kidney, Liposomes, Liver, Magnetic Resonance Imaging, Particle Size, Polymers, Silicon Dioxide, Nanotubes, Carbon, Quantum Dots, Dendrimers, Metal Nanoparticles
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
