Depression in patients with heart disease: the case for more trials

Liu, Stanley S; Ziegelstein, Roy C

doi:10.2217/fca.10.18

Cited by 15Cardiac Health and Mental HealthAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and Access

Depression in patients with heart disease: the case for more trials

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Liu, Stanley S, Ziegelstein, Roy C·2010·Future Cardiology

DOI 10.2217/fca.10.18PMC PMC2926794

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Abstract

Depression is common among patients with heart disease. It is an important comorbidity, both because of its well-known effect on the quality of life and also because it has a significant impact on the ability of patients with heart disease to engage in healthy behaviors and to avoid unhealthy ones. In addition, depression is associated with increased morbidity and mortality in those with established cardiovascular disease. However, no study has demonstrated that treatment of depression improves cardiac outcomes in patients with heart disease. Some have argued that additional trials are not necessary, and that the importance of depression argues for increased recognition and treatment even if it cannot be demonstrated that this improves morbidity and mortality. This article makes the case for more trials in this area, highlighting the importance of using the results of prior trials to generate hypotheses and provide directions for future studies in this area and noting the effect that demonstrating improved survival might have on clinical practice.

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Interventions not informed by consumer preferences are associated with poor treatment retention and low efficacy.
“are not informed by consumer preferences, which is associated with poor treatment retention and low efficacy45 46”
From Acceptance commitment therapy (ACT) for psychological distress associated with inflammatory bowel disease (IBD): protocol for a feasibility trial of the ACTforIBD programme (2022) · cites this paper as [46]
The section “Studying different methods of delivering depression treatment” (page unavailable) says collaborative care considers patients’ preferences and reports improved outcomes, but it does not compare care that ignores preferences or link it to retention or efficacy. The passages on adherence and treatment effects likewise do not establish that association; searches for patient preferences, retention, and efficacy found no passage that does. (LLM, conf=0.72)
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Authors: Liu, S. S., & Ziegelstein, R. C.
Affiliations: Johns Hopkins University (US)
Corresponding author: Ziegelstein, Roy C
ORCID: Ziegelstein, Roy C
Venue: Future Cardiology
Publisher: Informa UK Limited
Published: 2010-07
Volume: 6
Issue: 4
Pages: 547-556
ISSN: 1479-6678 (ISSN-L)
1744-8298
DOI: 10.2217/fca.10.18
PMC: PMC2926794
OpenAlex: W2162401843
Cited by: 15
References: 57
Citations by year: 2024: 1 · 2022: 1 · 2019: 1 · 2018: 3 · 2017: 2 · 2016: 1 · 2014: 2 · 2013: 1 · 2012: 1
FWCI: 0.21
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Future Cardiology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Center for Complementary and Alternative Medicine and by the Miller Family Scholar Program (R24AT004641)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords: depression, heart disease, cardiovascular comorbidity, depression treatment, cardiac outcomes, mortality, morbidity, quality of life, health behavior, clinical trials
MeSH terms: Clinical Trials as Topic, Depression, Depressive Disorder, Heart Diseases, Humans, Comorbidity

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Depression in patients with heart disease: the case for more trials

Abstract

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Record

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