Repetitive transcranial magnetic stimulation and drug addiction
Open accessAbstract
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique that is now being tested for its ability to treat addiction. This review discusses current research approaches and results of studies which measured the therapeutic use of rTMS to treat tobacco, alcohol and illicit drug addiction. The research in this area is limited and therefore all studies evaluating the therapeutic use of rTMS in tobacco, alcohol or illicit drug addiction were retained including case studies through NCBI PubMed ( http://www.ncbi.nlm.nih.gov ) and manual searches. A total of eight studies were identified that examined the ability of rTMS to treat tobacco, alcohol and cocaine addiction. The results of this review indicate that rTMS is effective in reducing the level of cravings for smoking, alcohol, and cocaine when applied at high frequencies to the dorsolateral prefrontal cortex (DLPFC). Furthermore, these studies suggest that repeated sessions of high frequency rTMS over the DLPFC may be most effective in reducing the level of smoking and alcohol consumption. Although work in this area is limited, this review indicates that rTMS is a promising modality for treating drug addiction.
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TMS applications to investigate and modulate SUD-related networks have grown exponentially across alcohol, cocaine, methamphetamine, opioid, cannabis, and tobacco use disorders.
“there has been an exponential growth in the application of TMS to investigate and modulate these networks in populations with SUDs including alcohol, cocaine, methamphetamine, opioid, cannabis, and tobacco use disorder [11,12,25–29].”
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- Authors
- Barr, M. S., Farzan, F., Wing, V. C., George, T. P., Fitzgerald, P. B., & Daskalakis, Z. J.
- Affiliations
- Centre for Addiction and Mental Health (CA)
- Beth Israel Deaconess Medical Center (US)
- Monash Alfred Psychiatry Research centre (AU)
- Corresponding author
- Daskalakis, Zafiris J.
- Venue
- International Review of Psychiatry
- Publisher
- Informa UK Limited
- Published
- 2011-10
- Volume
- 23
- Issue
- 5
- Pages
- 454-466
- ISSN
- 0954-0261 (ISSN-L)
- 1369-1627
- OpenAlex
- W2150822776
- Cited by
- 78
- References
- 130
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 4 · 2019: 7 · 2018: 8 · 2017: 6 · 2016: 5 · 2015: 11 · 2014: 11 · 2013: 6 · 2012: 4
- FWCI
- 0.59
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Review of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research
- National Institute on Drug Abuse (U01DA020830)
- Topics
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Keywords
- repetitive transcranial magnetic stimulation, drug addiction, tobacco dependence, alcoholism, cocaine dependence, craving reduction, dorsolateral prefrontal cortex, high-frequency rTMS, non-invasive brain stimulation, smoking cessation
- MeSH terms
- Appointments and Schedules, Clinical Trials as Topic, Humans, Outcome and Process Assessment, Health Care, Tobacco Use Disorder, Behavior, Addictive, Treatment Outcome, Prefrontal Cortex, Cocaine-Related Disorders, Alcohol-Related Disorders, Transcranial Magnetic Stimulation
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