Prevalence, Treatment, and Control of Depressive Symptoms in the United States: Results from the National Health and Nutrition Examination Survey (NHANES), 2005-2008
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BACKGROUND: depression remains a major public health problem that is most often evaluated and treated in primary care settings. The objective of this study was to examine the prevalence, treatment, and control of depressive symptoms in a national data sample using a common primary care screening tool for depression. METHODS: we analyzed a sample of adults (n = 4836) from 2005 to 2008 National Health and Nutrition Examination Survey data. Depressive symptoms were assessed using the Patient Health Questionnaire (PHQ-9) to determine the overall prevalence, rates of treatment, and antidepressant control of mild, moderate, moderately severe, and severe depressive symptoms. RESULTS: of the sample, 20.1% reported significant depressive symptoms (PHQ-9) score, ≥ 5), the majority of whom had mild depressive symptoms (PHQ-9) score, 5-9). Even among individuals with severe depressive symptoms, a large percentage (36.9%) received no treatment from a mental health professional or with antidepressant medication. Of those taking antidepressants, 26.4% reported mild depressive symptoms and 18.8% had moderate, moderately severe, or severe depressive symptoms. CONCLUSIONS: despite greater awareness and treatment of depression in primary care settings, the prevalence of depressive symptoms remains high, treatment levels remain low, and control of depressive symptoms are suboptimal. Primary care providers need to continue to focus their efforts on diagnosing and effectively treating this important disease.
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Most patients with depression report symptoms below the threshold for severe depression.
“This is concerning considering that most patients with depression report symptoms below the threshold for severe depression.12 13”
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- Authors
- Shim, R. S., Baltrus, P., Ye, J., & Rust, G.
- Affiliations
- Morehouse School of Medicine (US)
- Venue
- The Journal of the American Board of Family Medicine
- Published
- 2011-01-01
- Volume
- 24
- Issue
- 1
- Pages
- 33-38
- ISSN
- 1557-2625 (ISSN-L)
- 1558-7118
- PMC
- PMC3161724
- OpenAlex
- W2046197761
- Cited by
- 267
- References
- 28
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 7 · 2023: 8 · 2022: 22 · 2021: 17 · 2020: 22 · 2019: 21 · 2018: 36 · 2017: 14 · 2016: 21 · 2015: 24 · 2014: 20 · 2013: 14 · 2012: 14
- FWCI
- 24.88
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journal of the American Board of Family Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Atlanta Clinical and Translational Science Institute
- Morehouse School of Medicine
- National Institutes of Health (UL1TR000454)
- National Center for Research Resources (UL1RR025008)
- National Center for Advancing Translational Sciences
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- depressive symptoms, depression prevalence, antidepressant treatment, treatment gap, PHQ-9, primary care, depression screening, mental health service utilization
- MeSH terms
- Adolescent, Adult, Antidepressive Agents, Behavior Therapy, Cross-Sectional Studies, Depression, Female, Patient Care, Health Status Indicators, Health Surveys, Humans, Male, Mass Screening, Middle Aged, Nutrition Surveys, Psychometrics, Quality of Health Care, Surveys and Questionnaires, Risk Factors, Severity of Illness Index, United States, Prevalence, Confidence Intervals, Young Adult
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