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Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer’s disease11Abbreviations used: AD, Alzheimer’s disease; Endo III, Endonuclease III; 8OHA, 8-hydroxyadenine; 8OHG, 8-hydroxyguanine; 8OHdG, 8-hydroxy-2′-deoxyguanosine; Fapy-Ade, 4,6-diamino-5-formamidopyrimidine; Fapy-Gua, 2,6,-diamino-4-hydroxy-5-formamidopyrimidine; Fpg, formamidopyrimidine glycosilase; H2O2, hydrogen-peroxide; .OH, hydroxyl radical; PBS, phosphate-buffered saline; ROS, reactive oxygen species; RT, room temperature; SSB, single strand break

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RNAseq Analysis of FABP4 Knockout Mouse Hippocampal Transcriptome Suggests a Role for WNT/β-Catenin in Preventing Obesity-Induced Cognitive Impairment

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Mitochondrial Aconitase Enzymatic Activity: A Potential Long-Term Survival Biomarker in the Blood of ALS Patients

González‐Mingot, C., Mena, F. J. M., Iñarrea, P., Íñiguez, C., Capablo, J. L., Osta, R., Gil-Sánchez, A., Brieva, L., & Larrodé, P. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12103560 · Cited by 11 · see citing works

Metformin-improved cognitive impairment in patients with schizophrenia is correlated with activation of tricarboxylic acid cycle and restored functional connectivity of hippocampus

Cai, J., Xiao, J., Long, Y., Cao, T., Lin, C., Hei, G., Wang, W., Kang, D., Huang, J., Shao, T., et al. (2025) · BMC Medicine · doi:10.1186/s12916-025-04218-4 · Cited by 11 · see citing works

A novel gene selection method using GA/SVM and fisher criteria in Alzheimer's disease

Paylakhi, S. Z., Ozgoli, S., & Paylakhi, S. H. (2015) · Iranian Conference on Electrical Engineering · doi:10.1109/iraniancee.2015.7146349 · Cited by 9 · see citing works

Iron-Regulatory Genes are Associated with Neuroimaging Measures in HIV Infection

Fennema-Notestine, C., Thornton-Wells, T., Hulgan, T., Letendre, S., Ellis, R. J., Franklin, D., Anderson, A. M., Heaton, R., Bloss, C., Grant, I., et al. (2019) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00153-0 · Cited by 8 · see citing works

Redox Status, Procoagulant Activity, and Metabolome of Fresh Frozen Plasma in Glucose 6-Phosphate Dehydrogenase Deficiency

Tzounakas, V. L., Gevi, F., Georgatzakou, H. Τ., Zolla, L., Papassideri, I. S., Kriebardis, A. G., Rinalducci, S., & Antonelou, M. H. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00016 · Cited by 8 · see citing works

Acetylome analyses provide novel insights into the effects of chronic intermittent hypoxia on hippocampus-dependent cognitive impairment

Liu, F., Yan, W., Chen, C., Zeng, Y., Kong, Y., He, X., Pei, P., Wang, S., & Zhang, T. (2024) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1324458 · Cited by 7 · see citing works

Embracing complexity of (brain) aging

Polidori, M. C. (2024) · FEBS Letters · doi:10.1002/1873-3468.14941 · Cited by 8 · see citing works

Flavonoid-enrich extract of Autranella congolensis (Sapotaceae) protects against aluminium chloride-mediated Alzheimer’s disease-like oxidative stress in rat through the antioxidant properties

Ngoumen, D. J. N., Mandob, D. E., Ella, F. A., Ambamba, B. D. A., Nanhah, J. V. K., Fonkoua, M., & Ngondi, J. L. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-01142-x · Cited by 7 · see citing works

Analysis and identification of mitochondria-related genes associated with age-related hearing loss

Ma, T., Zeng, X., Liu, M., Xu, S., Wang, Y., Wu, Q., & Zhang, T. (2025) · BMC Genomics · doi:10.1186/s12864-025-11287-5 · Cited by 6 · see citing works

Molecular events linking cholesterol to Alzheimer's disease and inclusion body myositis in a rabbit model.

Liu, Q. Y., Koukiekolo, R., Zhang, D. L., Smith, B., Ly, D., Lei, J. X., & Ghribi, O. (2016) · Europe PMC (PubMed Central) · Cited by 6 · see citing works

Dynamic immune response characteristics of piglets infected with Actinobacillus pleuropneumoniae through omic

Zhu, R., Jiang, H., Wang, J., Bao, C., Liu, H., Li, F., & Lei, L. (2021) · AMB Express · doi:10.1186/s13568-021-01336-z · Cited by 4 · see citing works

From Lipids to Mitochondria: Shared Metabolic Alterations in Obesity and Alzheimer’s Disease

Uranga, R. M., & Allani, S. K. (2026) · Cells · doi:10.3390/cells15080672 · Cited by 3 · see citing works

Mitochondrial Aconitase enzymatic activity: a potential long survival biomarker in the blood of ALS patientsPreprint

González‐Mingot, C., Mena, F. J. M., Iñarrea, P., Íñiguez, C., Capablo, J. L., Osta, R., Gil-Sánchez, A., Peralta, S., Brieva, L., & Larrodé, P. (2023) · Research Square · doi:10.21203/rs.3.rs-2480485/v1 · Cited by 3 · see citing works

Comparison of Cerebral Cortex Transcriptome Profiles in Ischemic Stroke and Alzheimer’s Disease Models

Song, J. (2022) · Clinical Nutrition Research · doi:10.7762/cnr.2022.11.3.159 · Cited by 2 · see citing works

Obesity as a Neurobiologic Disorder: A Heavyweight Contender

Chávez-Castillo, M., Durán, P., Garrido, B., Díaz, A., Escalona, D., & Cano, C. (2022) · Current Psychiatry Research and Reviews · doi:10.2174/2666082218666220527120848 · Cited by 1 · see citing works

Micronutrients, Frailty, and Cognitive Impairment: Design and Preliminary Results from the CogLife 2.0 Study

Pickert, L., Dias, I. H. K., Thimm, A., Weber, J., Abdullah, S., Deelen, J., & Polidori, M. C. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-240654 · Cited by 1 · see citing works

Metabolic reprogramming in Alzheimer’s disease: Interaction between receptor tyrosine kinase signaling, noncoding RNAs, and Neuron–Glia energy networks

Karmakar, A., Roycowdhury, P., Sengupta, P., & Mukhopadhyay, D. (2026) · International review of neurobiology · doi:10.1016/bs.irn.2026.02.007

1,3-1,6 β-glucans reduce aging hallmarks in multiple organs and rapidly induce mitochondrial biogenesis and autophagy via direct effect on the killifish brain and human neuronsPreprint

Brogi, L., Fronte, B., Tonelli, F., Marchese, M., Cremisi, F., & Cellerino, A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.15.725450

Insights from NMR - based metabolomics elucidates key metabolic dysregulation in pancreatitis-induced acute respiratory distress syndrome: A step towards precision medicine

Marwari, D., Singh, A., Pandey, S., Azim, A., & Sinha, N. (2026) · Biophysical Chemistry · doi:10.1016/j.bpc.2026.107665

Integrated Multi-Omics Analysis Reveals ACO2 as an Oxidative-Stress-Related Biomarker in Alzheimer’s Disease

Dou, W., Chen, X., Hong, H., Liu, Q., Xiao, S., Li, L., Yu, J., & Tang, C. (2026) · Biomolecules · doi:10.3390/biom16101435

O3–01–05: Aconitase activity in lymphocyte mitochondria from AD, MCI and cognitively normal subjects

Mecocci, P., Mangialasche, F., Rinaldi, P., Metastasio, A., Feliziani, F. T., Cecchetti, R., Bastiani, P., Baglioni, M., & Mariani, E. (2006) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2006.05.191

P4‐143: Mitochondrial aconitase of aged and Alzheimer brain as a target for endogenous anti‐ and pro‐oxidants

Karelson, E., Raukas, M., Rebane, R., Bogdanović, N., Zilmer, M., & Jefremov, V. (2009) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2009.04.811

P3‐181: Oxidative damage and mitochondrial dysfunction in patients with mild cognitive impairment and Alzheimer's disease

Baldeiras, I., Santana, I. J., Proença, M. T., Garrucho, M. H., Pascoal, R., Rodrigues, A. S., Duro, D., Silva, D. F., Cardoso, S. M., & Oliveira, C. R. (2010) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2010.05.1679 · Cited by 4 · see citing works

Mitochondrial Alterations in Peripheral Mononuclear Blood Cells from Alzheimer’s Disease and Mild Cognitive Impairment Patients

Delbarba, A., Abate, G., Prandelli, C., Marziano, M., Buizza, L., Varas, N. A., Novelli, A., Cuetos, F., Martínez, C., Lanni, C., et al. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/5923938 · Cited by 80 · see citing works

Peripheral Mitochondrial Dysfunction in Alzheimer’s Disease: Focus on Lymphocytes

Leuner, K., Schulz, K. L., Schuett, T., Pantel, J., Prvulovic, D., Rhein, V. F., Savaskan, E., Czech, C., Eckert, A., & Müller, W. E. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8300-y · Cited by 127 · see citing works